[Hub]/) : Traits : Impedance of whole body : ← →

chr4:102,852,939-104,815,937

Best TWAS P=1.98e-10 · Best GWAS P=9.93e-09 conditioned to 0.25

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
33	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPE	0.04	0.01	enet	10	0.02	2.6e-03	5.33	-6.4	2.0e-10	-0.79	0.01	0.92	TRUE
15	GTEx	Colon Sigmoid	CISD2	0.20	0.24	enet	15	0.13	2.1e-05	5.52	-6.0	2.4e-09	-0.69	0.06	0.94	FALSE
3	GTEx	Adipose Visceral Omentum	UBE2D3	0.07	0.00	enet	23	0.02	3.2e-02	5.65	-6.0	2.5e-09	-0.47	0.05	0.72	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	UBE2D3	0.05	0.06	blup	337	0.07	5.0e-09	5.49	-5.9	4.1e-09	-0.76	0.04	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SLC9B1	0.13	0.23	enet	24	0.24	4.4e-29	5.67	-5.8	6.0e-09	-0.76	0.05	0.95	FALSE
39	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CISD2	0.05	0.01	blup	18	0.06	1.9e-03	5.60	-5.8	6.0e-09	-0.67	0.01	0.69	FALSE
7	GTEx	Artery Coronary	CISD2	0.14	0.15	lasso	8	0.12	7.4e-05	-4.85	-5.7	9.1e-09	-0.66	0.06	0.89	FALSE
4	GTEx	Adrenal Gland	CISD2	0.08	0.03	lasso	2	0.03	4.1e-02	5.64	-5.7	1.1e-08	-0.62	0.06	0.85	FALSE
11	GTEx	Breast Mammary Tissue (Male)	CISD2	0.15	0.02	lasso	3	-0.01	6.5e-01	5.69	-5.7	1.1e-08	-0.64	0.04	0.41	FALSE
38	The Cancer Genome Atlas	Lung Adenocarcinoma	MANBA	0.13	0.10	blup	69	0.10	4.5e-12	4.94	5.7	1.1e-08	0.73	0.21	0.79	FALSE
26	NTR	Blood	MANBA	0.01	0.00	bslmm	390	0.01	3.1e-03	4.45	5.7	1.4e-08	0.63	0.09	0.13	FALSE
9	GTEx	Brain Cerebellum	CISD2	0.13	0.18	lasso	3	0.17	1.1e-05	5.65	-5.7	1.5e-08	-0.64	0.05	0.94	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	CISD2	0.15	0.34	lasso	9	0.34	1.2e-44	5.64	-5.7	1.5e-08	-0.65	0.05	0.95	FALSE
5	GTEx	Artery Aorta	UBE2D3	0.07	0.06	lasso	5	0.04	3.5e-03	5.65	-5.6	1.7e-08	-0.64	0.06	0.91	FALSE
40	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBE2D3	0.03	0.04	enet	11	0.03	1.4e-04	5.55	-5.6	1.7e-08	-0.67	0.02	0.97	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	CISD2	0.05	0.08	enet	5	0.06	1.9e-06	5.53	-5.6	1.9e-08	-0.65	0.01	0.99	FALSE
14	GTEx	Cells Transformed fibroblasts	UBE2D3	0.11	0.09	enet	13	0.08	2.3e-06	5.53	-5.6	2.0e-08	-0.65	0.06	0.94	FALSE
25	GTEx	Uterus	CISD2	0.34	0.22	enet	25	0.19	8.9e-05	5.49	-5.6	2.0e-08	-0.64	0.05	0.90	FALSE
6	GTEx	Artery Aorta	CISD2	0.10	0.08	lasso	4	0.06	1.8e-04	5.52	-5.6	2.2e-08	-0.64	0.05	0.94	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CISD2	0.12	0.04	enet	12	0.07	5.0e-03	5.40	-5.6	2.3e-08	-0.65	0.06	0.77	FALSE
8	GTEx	Artery Tibial	CISD2	0.11	0.12	lasso	4	0.10	3.1e-08	5.70	-5.5	3.1e-08	-0.60	0.05	0.95	FALSE
18	GTEx	Lung	CISD2	0.06	0.05	enet	10	0.04	5.4e-04	5.49	-5.5	3.6e-08	-0.61	0.05	0.94	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	UBE2D3	0.11	0.00	enet	17	0.00	2.5e-01	0.82	-5.5	3.6e-08	-0.59	0.06	0.75	FALSE
17	GTEx	Esophagus Muscularis	CISD2	0.19	0.22	enet	25	0.21	6.2e-13	5.40	-5.5	3.9e-08	-0.58	0.06	0.94	FALSE
13	GTEx	Cells Transformed fibroblasts	MANBA	0.26	0.22	lasso	9	0.27	1.9e-20	4.55	5.5	4.4e-08	0.70	0.86	0.14	FALSE
24	GTEx	Thyroid	CISD2	0.12	0.07	lasso	3	0.05	8.8e-05	5.49	-5.5	4.7e-08	-0.63	0.05	0.94	FALSE
10	GTEx	Breast Mammary Tissue	CISD2	0.21	0.08	enet	13	0.08	6.0e-05	5.53	-5.5	5.0e-08	-0.59	0.06	0.94	FALSE
23	GTEx	Small Intestine Terminal Ileum	CISD2	0.29	0.19	enet	34	0.15	3.2e-04	5.64	-5.4	5.9e-08	-0.55	0.05	0.85	FALSE
2	GTEx	Adipose Subcutaneous	CISD2	0.06	0.09	enet	12	0.06	7.3e-06	5.47	-5.4	6.7e-08	-0.63	0.06	0.94	FALSE
22	GTEx	Skin Sun Exposed Lower leg	CISD2	0.12	0.20	lasso	14	0.20	1.1e-16	5.45	-5.4	7.9e-08	-0.68	0.06	0.94	FALSE
19	GTEx	Ovary	CISD2	0.12	0.12	lasso	4	0.07	6.9e-03	5.49	-5.3	9.6e-08	-0.63	0.06	0.75	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	MANBA	0.20	0.30	enet	26	0.31	2.3e-40	5.23	-5.3	1.0e-07	-0.76	0.25	0.75	FALSE
16	GTEx	Esophagus Mucosa	CISD2	0.12	0.06	enet	13	0.05	2.1e-04	5.51	-5.3	1.1e-07	-0.61	0.07	0.93	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	CISD2	0.02	0.02	enet	7	0.02	1.3e-03	-4.74	5.3	1.1e-07	0.59	0.01	0.85	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	RP11-10L12.4	0.08	0.10	lasso	7	0.09	5.1e-12	5.45	-5.3	1.5e-07	-0.54	0.05	0.95	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MANBA	0.03	0.03	blup	71	0.04	2.0e-05	4.64	5.2	1.9e-07	0.66	0.04	0.95	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	CENPE	0.06	0.07	lasso	15	0.06	9.4e-09	4.44	5.2	2.0e-07	0.64	0.90	0.10	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	UBE2D3	0.02	0.02	enet	6	0.02	3.7e-03	5.68	-5.2	2.3e-07	-0.49	0.02	0.82	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	MANBA	0.11	0.16	lasso	4	0.16	3.4e-32	4.94	5.1	2.6e-07	0.76	0.26	0.73	FALSE
34	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MANBA	0.15	0.09	lasso	6	0.09	1.0e-10	4.53	5.1	2.7e-07	0.67	0.62	0.38	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	CISD2	0.13	0.14	enet	18	0.10	6.0e-06	5.54	-5.1	2.8e-07	-0.48	0.05	0.95	FALSE