[Hub]/) : Traits : Impedance of leg (right) :

chr16:870,950-2,446,021

Best TWAS P=1.64e-08 · Best GWAS P=7.56e-10 conditioned to 3.56e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HN1L 0.08 0.01 blup 487 0.04 2.4e-05 -4.2 5.3 1.2e-07 -0.47 0.32 0.44 FALSE
2 GTEx Cells Transformed fibroblasts TMEM204 0.10 0.01 enet 9 0.03 5.0e-03 -4.4 -5.5 5.2e-08 0.64 0.11 0.66 FALSE
3 ROSMAP Brain Pre-frontal Cortex IFT140 0.11 0.02 bslmm 498 0.07 5.9e-09 0.2 5.2 1.7e-07 -0.73 0.19 0.81 FALSE
4 YFS Blood CRAMP1L 0.02 0.01 lasso 5 0.01 1.6e-04 -4.3 -5.7 1.6e-08 0.77 0.56 0.41 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma TMEM204 0.02 0.01 blup 64 0.01 4.4e-03 -4.2 -5.3 1.0e-07 0.63 0.08 0.44 FALSE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MAPK8IP3 0.18 0.06 blup 77 0.10 8.7e-06 -3.7 -5.3 1.4e-07 0.75 0.10 0.74 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TPSAB1 0.14 0.01 enet 11 0.10 1.6e-05 3.4 -5.2 1.9e-07 0.00 0.00 0.01 TRUE
8 The Cancer Genome Atlas Esophageal Carcinoma CRAMP1L 0.11 0.08 blup 60 0.07 2.2e-03 -4.5 -5.6 2.2e-08 0.87 0.02 0.84 FALSE