Best TWAS P=1.64e-08 · Best GWAS P=7.56e-10 conditioned to 3.56e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HN1L | 0.08 | 0.01 | blup | 487 | 0.04 | 2.4e-05 | -4.2 | 5.3 | 1.2e-07 | -0.47 | 0.32 | 0.44 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | TMEM204 | 0.10 | 0.01 | enet | 9 | 0.03 | 5.0e-03 | -4.4 | -5.5 | 5.2e-08 | 0.64 | 0.11 | 0.66 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | IFT140 | 0.11 | 0.02 | bslmm | 498 | 0.07 | 5.9e-09 | 0.2 | 5.2 | 1.7e-07 | -0.73 | 0.19 | 0.81 | FALSE |
| 4 | YFS | Blood | CRAMP1L | 0.02 | 0.01 | lasso | 5 | 0.01 | 1.6e-04 | -4.3 | -5.7 | 1.6e-08 | 0.77 | 0.56 | 0.41 | TRUE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TMEM204 | 0.02 | 0.01 | blup | 64 | 0.01 | 4.4e-03 | -4.2 | -5.3 | 1.0e-07 | 0.63 | 0.08 | 0.44 | FALSE |
| 6 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | MAPK8IP3 | 0.18 | 0.06 | blup | 77 | 0.10 | 8.7e-06 | -3.7 | -5.3 | 1.4e-07 | 0.75 | 0.10 | 0.74 | FALSE |
| 7 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | TPSAB1 | 0.14 | 0.01 | enet | 11 | 0.10 | 1.6e-05 | 3.4 | -5.2 | 1.9e-07 | 0.00 | 0.00 | 0.01 | TRUE |
| 8 | The Cancer Genome Atlas | Esophageal Carcinoma | CRAMP1L | 0.11 | 0.08 | blup | 60 | 0.07 | 2.2e-03 | -4.5 | -5.6 | 2.2e-08 | 0.87 | 0.02 | 0.84 | FALSE |