TWAS hub - HN1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0820	0.0310	1.0e-04	0.010	0.037	0.018	0.035	0.013	1.7e-02	2.4e-05	2.3e-03	3.7e-05	8.7e-03
2	GTEx	Adipose Subcutaneous	0.1370	0.0440	3.5e-06	0.046	NA	0.083	NA	0.083	1.1e-04	NA	2.8e-07	NA	2.7e-07
3	GTEx	Artery Aorta	0.1370	0.0480	3.1e-04	0.084	NA	0.085	NA	0.117	2.2e-05	NA	1.9e-05	NA	5.4e-07
4	GTEx	Artery Tibial	0.1162	0.0446	6.0e-04	0.078	NA	0.098	NA	0.081	9.7e-07	NA	4.0e-08	NA	6.0e-07
5	GTEx	Muscle Skeletal	0.1101	0.0411	2.7e-04	0.053	NA	0.022	NA	0.043	6.1e-06	NA	2.8e-03	NA	4.1e-05
6	GTEx	Nerve Tibial	0.1636	0.0501	4.8e-05	0.031	NA	0.082	NA	0.107	2.9e-03	NA	2.0e-06	NA	5.8e-08
7	GTEx	Prostate	0.3790	0.1120	3.4e-03	-0.011	NA	-0.003	NA	-0.010	7.7e-01	NA	3.8e-01	NA	7.0e-01
8	METSIM	Adipose	0.0753	0.0312	1.4e-05	0.056	0.037	0.038	0.037	0.048	8.4e-09	2.6e-06	2.0e-06	2.7e-06	8.0e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Illnesses of father: Heart disease	9.0	12.5	21.8	-3.6	-3.9	-4.3	-4.7	-3.5	1.9	-1.6	-3.7
Diabetes (father)	5.3	6.6	10.9	2.1	3.0	2.6	2.3	3.3	-2.4	0.2	3.3
Supplements: Calcium	4.7	5.2	8.9	2.4	2.3	3.0	2.0	2.4	-2.5	-0.5	2.4
Hypothyroidism (self reported)	4.0	9.2	20.4	-4.5	-2.8	-3.6	-2.7	-3.0	1.8	-0.9	-3.4
Ever smoked	3.7	6.5	12.6	-3.6	-2.0	-2.7	-3.5	-2.4	0.5	2.0	-2.4
Depressed Affect (Nagel 2018)	3.6	7.6	11.5	1.4	3.3	2.5	3.4	2.6	-2.2	-2.7	3.4
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	9.7	1.8	1.9	2.7	3.1	2.2	-0.7	-0.8	1.8
Severe depression (siblings)	3.4	3.8	7.0	2.0	2.3	2.2	2.6	1.6	-1.0	0.2	2.4
Fed-up feelings	3.4	6.1	7.6	1.5	2.6	2.6	2.5	2.3	-2.8	-2.6	2.7
Loneliness, isolation	3.4	4.8	8.9	0.5	2.5	2.1	3.0	2.2	-1.6	-2.1	2.5
Prostate Cancer	3.3	4.6	8.2	1.2	2.8	2.2	2.1	1.4	-1.2	-2.5	2.9
Fasting Glucose	3.3	3.9	6.7	1.1	2.2	2.2	1.2	2.6	-2.4	0.1	2.5
Length of working week for main job	3.2	3.6	5.3	-2.2	-1.9	-1.9	-1.6	-2.3	1.1	2.2	-1.8
Serious illness, injury or assault to yourself	3.1	3.8	8.4	1.6	2.3	2.1	0.8	2.1	-2.9	-0.7	2.0
Hypothyroidism/myxoedema (self-reported)	3.1	6.0	14.0	-3.7	-2.3	-2.8	-1.9	-2.7	1.6	-0.6	-2.6
Chronic bronchitis/emphysema (mother)	3.0	3.5	8.5	0.8	2.0	2.1	2.0	2.9	-1.4	0.1	2.2
Hypertension (Self-reported)	3.0	8.4	17.1	-4.1	-3.0	-3.0	-2.8	-3.2	1.3	-1.6	-3.1
Cardiovascular Disease	2.9	9.6	18.6	-4.3	-3.1	-3.3	-3.6	-3.1	1.4	-2.1	-2.9
Illnesses of father: None of the above (group 1)	2.7	3.3	7.8	1.5	1.6	1.7	2.5	1.3	0.7	2.8	1.5
Miserableness	2.7	4.6	8.1	2.0	2.0	1.9	2.8	2.8	-1.7	-1.0	2.4
Medication: Levothyroxine sodium	2.6	4.5	12.9	-3.6	-1.7	-2.7	-1.5	-2.2	0.7	-0.3	-2.2
Age at first live birth	2.6	4.6	9.2	-0.5	-2.0	-2.4	-2.0	-3.0	2.2	1.4	-2.6
Medication: Bendroflumethiazide	2.6	3.9	11.4	-3.4	-2.2	-1.9	-1.7	-1.8	1.4	-0.6	-1.8
Father’s age at death	2.5	3.3	5.4	1.6	1.4	2.3	2.0	2.2	-2.1	0.4	1.8
Depression (self-reported)	2.5	3.0	6.2	1.0	2.1	2.2	1.9	1.9	-0.5	-0.2	2.5
Lung cancer (father)	2.5	2.9	6.6	-0.5	-1.9	-1.7	-1.8	-1.6	2.6	-1.2	-1.7
Medication: Blood pressure	2.5	4.8	13.1	-3.6	-1.6	-2.9	-2.1	-2.3	0.8	-0.6	-1.8
Alzheimer’s Disease (in father)	2.4	2.6	6.4	1.0	0.8	2.5	1.0	1.6	-2.4	-1.4	1.4
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	6.5	-2.5	-1.3	-1.8	-0.7	-1.3	2.0	1.0	-1.1
High blood pressure (siblings)	2.3	3.3	4.7	-2.0	-1.8	-2.1	-2.0	-1.2	2.2	0.5	-1.9
Number of self-reported non-cancer illnesses	2.3	3.9	16.7	-4.1	-0.9	-2.4	-2.2	-0.9	0.5	-1.1	-1.1
Ovarian Cancer	2.2	2.9	7.5	1.0	1.7	1.2	1.0	1.5	-1.8	-2.7	1.9
LDL Cholesterol	2.2	3.4	10.5	1.0	1.5	2.2	3.2	2.5	-0.8	-0.8	1.1
Average weekly spirits intake	2.2	2.7	5.7	-2.4	-1.5	-1.8	-1.7	-1.2	1.8	0.7	-1.6
Vascular/heart problems diagnosed by doctor	2.2	6.1	10.6	3.3	2.3	2.7	2.7	2.6	-1.1	2.5	2.2
High blood pressure	2.1	5.8	12.8	-3.6	-2.3	-2.6	-2.5	-2.6	1.0	-1.6	-2.4
Rheumatoid Arthritis	2.0	2.8	6.0	-1.9	-1.4	-1.9	-0.7	-2.5	2.1	0.6	-1.5
Past tobacco smoking	2.0	3.6	8.6	1.9	1.9	2.0	2.9	1.9	0.2	-1.2	2.0
Illnesses of siblings	2.0	2.7	4.8	1.0	2.2	1.8	1.9	1.4	-1.9	-0.1	1.9
Birth weight of first child	2.0	3.6	7.7	0.6	2.8	2.4	1.8	2.3	-1.5	-0.6	2.0
Triglycerides	1.9	3.0	6.4	0.8	1.6	1.9	2.5	2.4	-0.2	-1.4	1.9
Impedance of arm (right)	1.9	8.7	32.7	5.7	1.8	3.2	3.0	3.0	-1.2	0.5	2.2
Alcohol usually taken with meals	1.8	3.0	6.9	1.2	1.7	1.8	2.6	2.2	-1.0	0.8	1.6
Hair/balding pattern: Pattern 3	1.8	2.7	5.0	-1.4	-1.3	-1.8	-0.7	-2.0	2.2	1.1	-1.9
Impedance of arm (left)	1.8	8.1	31.0	5.6	1.8	3.1	2.6	2.7	-1.4	0.5	2.2
Age at last live birth	1.8	2.6	4.7	-0.7	-1.2	-2.0	-2.2	-2.1	1.0	1.1	-1.8
Eye problems/disorders: Glaucoma	1.8	2.2	7.2	0.3	0.9	1.6	0.9	1.8	-2.7	-0.2	1.6
Ever depressed for a whole week	1.8	2.3	6.8	-2.6	-1.3	-1.4	-1.0	-1.2	1.5	0.7	-1.6
Heart disease (siblings)	1.8	2.2	3.4	-1.8	-1.9	-1.4	-1.3	-1.0	1.4	0.8	-1.8
Headache pain in last month	1.7	2.9	7.3	1.3	1.5	2.3	1.5	2.7	-1.4	0.0	1.5
Relative age voice broke	1.6	2.5	5.9	-1.0	-1.7	-2.4	-1.8	-2.0	-0.3	-0.1	-1.7
Smoking status: Previous	1.6	2.3	4.6	-0.9	-2.1	-1.5	-2.1	-1.8	0.3	0.4	-1.8
Heart attack/myocardial infarction (self-reported)	1.6	2.1	6.8	-1.1	-1.3	-1.5	-0.9	-1.2	0.6	-2.6	-1.3
Qualifications: CSEs or equivalent	1.5	2.0	4.8	2.1	0.6	1.7	2.2	1.5	-0.7	0.2	0.9
Neck or shoulder pain in last month	1.5	2.1	3.5	-1.9	-1.3	-1.7	-1.9	-1.6	1.0	0.8	-1.0
Pack years of smoking	1.5	2.1	3.2	0.9	1.5	1.5	1.5	1.3	-1.4	-1.7	1.8
Bipolar Disorder or Schizophrenia	1.4	3.5	8.1	1.5	2.8	2.2	0.0	2.1	0.0	0.6	2.8
Pack years adult smoking proportion	1.4	2.2	3.5	0.9	1.6	1.6	1.4	1.3	-1.4	-1.6	1.9
Hearing difficulty/problems with background noise	1.4	2.2	5.1	-1.3	1.7	0.4	0.9	1.4	-2.3	-1.9	1.1
Heart attack	1.4	1.9	6.0	-1.1	-1.2	-1.6	-0.9	-1.1	0.4	-2.5	-1.2
Handedness (chirality/laterality): Left-handed	1.4	1.7	5.0	-0.4	2.2	0.8	1.1	1.4	-1.4	-0.5	1.5
Medication: Lisinopril	1.4	1.9	3.4	-1.6	-1.5	-1.4	0.0	-1.9	1.5	0.5	-1.6
Age at First Birth	1.3	1.9	4.2	-1.0	-1.5	-1.8	-2.0	-1.3	0.5	0.1	-1.6
Smoking Status	1.3	3.2	11.2	-2.2	-0.9	-1.9	-3.3	-1.8	-0.5	0.7	-1.0
Sensitivity / hurt feelings	1.3	2.2	6.5	0.5	1.2	1.4	2.5	1.7	-0.4	-1.7	1.4
Angina	1.3	1.7	3.6	-1.5	-1.0	-1.6	-1.9	-1.0	1.1	-0.3	-1.3
Arm fat-free mass (right)	1.3	6.7	11.5	-3.4	-1.9	-2.9	-1.2	-2.8	2.9	2.1	-2.6
Mouth/teeth dental problems: Loose teeth	1.3	1.6	2.5	-0.3	-1.6	-1.2	-1.6	-1.1	1.2	-1.2	-1.4
Neuroticism (Nagel 2018)	1.2	2.7	6.1	-0.3	1.6	1.1	2.2	1.8	-0.5	-2.5	1.9
Schizophrenia (2018)	1.2	2.6	6.6	1.2	2.6	1.9	0.0	1.8	0.0	-0.2	2.4
Systolic Blood Pressure	1.2	5.8	14.3	-3.8	-2.2	-2.0	-3.5	-2.5	0.8	-0.4	-2.0
Townsend deprivation index at recruitment	1.2	1.6	4.2	-0.5	-1.9	-1.3	-2.0	-1.1	0.4	0.4	-1.4
Number of live births	1.2	1.8	4.5	-0.8	2.1	1.1	1.6	1.5	-0.8	0.4	1.4
Tense / ‘highly strung’	1.2	2.0	5.9	0.6	1.5	1.6	2.4	1.5	0.4	-0.7	1.4
Number of full brothers	1.2	1.6	4.6	0.6	-2.1	-0.9	-0.4	-1.1	1.4	0.5	-1.8
Overall health rating	1.2	2.6	6.2	-1.1	-1.5	-2.0	-1.7	-2.5	0.8	-1.3	-1.5
Intelligence (Savage-Jansen 2018)	1.1	3.4	13.4	-3.7	0.0	-1.9	-0.8	-0.2	0.7	2.8	-1.3
Chronic bronchitis/emphysema (father)	1.1	1.3	2.5	-0.7	-1.2	-1.6	-1.2	-1.2	1.0	-0.5	-1.3
Trunk fat-free mass	1.1	6.1	10.1	-3.1	-1.6	-2.6	-0.7	-2.8	3.2	2.6	-2.2
Trunk predicted mass	1.1	6.2	10.2	-3.2	-1.6	-2.6	-0.7	-2.7	3.2	2.5	-2.2
Birth weight	1.1	2.4	6.1	0.7	2.3	1.5	2.5	1.0	-0.6	0.4	2.0
Health satisfaction	1.1	1.4	2.7	-1.1	-1.0	-1.5	-0.8	-1.3	0.3	-1.6	-1.2
Migraine (self-reported)	1.1	1.3	5.6	1.8	-0.2	0.9	0.0	0.9	-0.0	-2.4	0.1
Arm predicted mass (right)	1.1	5.8	9.9	-3.1	-1.8	-2.8	-1.3	-2.6	2.7	2.0	-2.4
Illnesses of father: High blood pressure	1.1	1.4	5.1	-0.7	-0.5	-0.5	-2.3	-0.6	-1.1	-1.8	-0.3
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.2	-2.1	0.3	0.6	0.8	1.4	-1.6	-0.1	0.8
Impedance of whole body	1.1	5.8	33.4	5.8	0.4	2.7	1.2	1.6	-0.5	-0.1	1.0
Schizophrenia vs Biploar Disorder	1.0	1.3	4.6	-2.1	-0.8	-1.9	0.0	-0.7	0.0	0.0	-1.2
Allergy or Eczema	1.0	2.5	5.2	1.0	1.9	2.0	0.9	2.3	-1.2	0.8	1.8
Hearing difficulty/problems: Yes	1.0	1.5	6.6	-2.6	1.1	-0.7	-0.6	0.7	-1.3	-1.1	0.4
Alcohol intake versus 10 years previously	1.0	1.6	3.3	1.3	-1.8	-0.6	-0.8	-1.4	0.6	1.6	-1.2
Breastfed as a baby	1.0	1.3	2.3	-1.0	-1.1	-1.5	-1.1	-0.6	-0.2	1.5	-1.3
Loud music exposure frequency	1.0	1.1	5.4	-1.1	-0.1	-0.9	-0.6	-0.7	0.4	-2.3	-0.3
Glaucoma (self-reported)	1.0	1.2	2.6	0.0	0.7	1.3	0.8	1.5	-1.6	0.4	1.2
Medication: Ventolin 100micrograms inhaler	1.0	1.2	2.7	1.6	1.0	1.3	0.4	1.0	-1.5	0.9	0.5
Eye problems/disorders: None of the above	1.0	1.1	3.6	-1.1	-0.8	-0.9	0.5	-1.0	1.9	0.7	-1.1
Medication: Omeprazole	1.0	1.1	6.2	-2.5	-0.5	-0.2	-0.3	0.7	-1.3	0.5	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	8.3	-0.2	0.3	0.4	-0.1	0.2	-0.8	2.9	0.2
Knee pain experienced in last month	1.0	1.6	4.3	-0.8	-0.8	-2.1	-0.6	-1.4	1.4	1.0	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.0	-0.3	0.7	0.8	-0.7	2.0	-0.4	-1.5	1.3
Whole body fat-free mass	1.0	5.6	10.8	-3.3	-1.4	-2.8	-0.5	-2.4	2.7	2.6	-2.1
Mood swings	1.0	1.9	3.7	1.0	1.3	1.1	1.6	1.0	-0.9	-1.9	1.6
Breast cancer (self-reported)	1.0	1.2	3.8	-1.9	-0.7	-1.4	-1.2	0.1	1.1	0.0	-1.0
Guilty feelings	1.0	1.5	4.5	-2.1	-1.2	-1.2	-0.6	0.2	1.8	-0.1	-1.0
Medication: Paracetamol	1.0	1.6	3.6	1.3	1.0	1.1	1.9	1.7	0.2	-1.2	1.0
Ever had prostate specific antigen (PSA) test	1.0	1.1	2.6	-0.7	-0.8	-0.9	-1.6	-1.3	-0.2	1.3	-1.2
Basal cell carcinoma (self-reported)	1.0	1.2	3.4	-0.9	1.0	1.3	0.5	1.0	-1.9	-0.6	1.1
Arm predicted mass (left)	1.0	5.0	8.3	-2.9	-1.7	-2.7	-0.8	-2.2	2.4	2.2	-2.4
Mean Putamen Volume	0.9	1.0	3.2	0.0	1.6	0.2	0.1	1.8	-0.7	0.1	1.3
Schizophrenia (2014)	0.9	2.0	4.5	1.3	2.1	1.5	0.0	1.8	0.0	0.4	2.1
Chronotype (morning person)	0.9	2.2	4.0	1.7	1.4	1.3	1.5	0.8	-1.7	-1.0	2.0
Number of treatments/medications taken	0.9	1.5	3.2	-1.6	1.0	0.5	-0.4	1.0	-1.8	-1.8	1.0
Impedance of leg (right)	0.9	4.5	28.1	5.3	-1.3	2.3	-0.3	0.5	0.5	-0.7	-0.1
Taking other prescription medications	0.9	1.3	6.7	-2.6	-0.4	-1.1	-1.3	-0.0	-0.5	-0.6	-0.5
Age when periods started (menarche)	0.9	2.1	5.0	0.4	-1.5	-1.2	-0.6	-2.2	0.9	2.0	-1.6
Hayfever, allergic rhinitis or eczema	0.9	1.9	3.5	1.0	1.8	1.7	0.7	1.9	-0.5	1.0	1.7
Multivitamins +/- minerals	0.9	1.1	2.8	1.7	0.9	1.4	1.6	0.4	0.1	0.1	0.7
Impedance of leg (left)	0.9	4.2	22.0	4.7	-2.2	1.2	-1.0	-0.6	1.5	-0.5	-1.1
Nervous feelings	0.9	1.6	2.8	0.3	1.2	1.4	1.7	1.5	-0.5	-1.6	1.4
Worry too long after embarrassment	0.9	1.5	3.1	-1.6	-1.3	-1.5	-0.2	-0.6	1.7	-0.4	-1.3
Pulse wave peak to peak time	0.9	1.1	2.6	-1.4	-0.2	-1.6	-0.6	-0.7	1.6	0.7	-0.3
Angina (self-reported)	0.9	1.2	2.6	-1.4	-0.8	-1.4	-1.6	-0.8	0.9	-0.4	-1.0
Mean time to correctly identify matches	0.9	1.8	3.6	-1.3	-1.9	-1.3	-1.9	-1.1	0.2	-0.6	-1.5
Leg fat-free mass (right)	0.9	4.8	11.3	-3.4	-0.8	-3.1	-0.2	-2.0	2.2	2.3	-1.8
Medication for cholesterol	0.9	1.4	5.2	2.3	0.8	1.4	1.3	1.0	-0.6	0.2	0.7
Osteoarthritis (self-reported)	0.9	1.2	4.8	-0.9	-0.2	-1.3	-0.4	-0.5	2.2	1.4	-0.1
Whole body water mass	0.9	5.3	10.0	-3.2	-1.2	-2.7	-0.4	-2.3	2.6	2.6	-2.0
Leg predicted mass (right)	0.9	4.8	11.6	-3.4	-0.7	-3.1	-0.3	-1.9	2.1	2.3	-1.7
Arm fat-free mass (left)	0.9	4.6	8.6	-2.9	-1.5	-2.5	-0.9	-2.1	2.3	2.0	-2.1
Crohns Disease (2012)	0.8	1.2	3.9	1.2	0.5	1.2	-0.4	0.0	-1.1	-2.0	1.0
Lung FEV1/FVC ratio	0.8	4.1	8.4	-0.7	-1.9	-2.1	-1.9	-2.1	2.4	2.9	-1.6
Medication: Co-codamol	0.8	1.0	2.5	-0.6	1.1	0.3	-0.1	1.6	-1.1	1.4	0.7
Stomach or abdominal pain in last month	0.8	1.0	3.2	-0.1	-1.8	-0.9	-1.0	-0.5	0.8	1.0	-1.1
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.4	-0.9	-1.5	-0.9	-1.1	-1.1	-0.2	0.3	-1.1
Number of incorrect matches in round	0.8	1.3	2.7	-1.2	-0.9	-1.6	-1.6	-1.4	-0.1	0.7	-0.9
Had other major operations	0.8	0.9	2.5	-0.9	1.4	0.6	0.5	0.7	-1.6	0.5	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	2.4	-1.3	-1.6	-1.2	-0.5	-1.2	0.5	-0.8	-1.4
Falls in the last year	0.8	1.1	2.2	-1.3	-0.7	-1.5	-0.6	-1.3	0.7	1.3	-0.7
Standing height	0.8	7.8	21.3	0.5	-1.8	-1.6	0.6	-2.8	4.6	4.5	-2.5
Medication: Paracetamol	0.8	1.4	4.2	0.7	1.0	1.1	1.2	2.1	-0.5	-1.0	1.2
Emphysema/chronic bronchitis	0.8	0.9	2.6	-1.6	-0.3	-1.2	-1.1	-0.6	-0.6	-0.9	-0.1
Number of full sisters	0.8	1.0	3.2	0.2	0.8	0.8	1.8	1.2	-1.1	-0.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	6.4	0.6	-0.3	0.1	0.8	-1.0	2.5	2.3	-0.1
Diabetes diagnosed by doctor	0.8	1.3	4.1	0.7	1.3	0.3	2.0	1.0	0.1	-1.7	0.8
Tinnitus: Yes, now most or all of the time	0.8	1.0	3.2	-1.0	-0.6	-0.3	-1.4	0.2	1.1	-1.8	-0.3
Pain type(s) experienced in last month: Hip pain	0.8	1.1	2.3	0.5	1.5	0.6	0.3	1.1	-1.0	1.2	1.3
Basal metabolic rate	0.8	4.5	7.1	-2.7	-1.2	-2.7	-0.4	-2.0	2.4	2.7	-2.0
Lupus	0.7	1.1	2.1	-1.4	-0.4	-0.7	-1.3	-1.5	1.5	-0.1	-0.7
Blood Red Count	0.7	7.1	12.5	-2.6	-2.8	-3.3	-2.3	-2.1	3.0	0.5	-3.5
Height	0.7	13.4	36.2	-0.2	-2.6	-2.4	0.8	-3.1	6.0	5.9	-3.5
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.5	0.1	0.9	0.9	0.7	1.9	-0.7	-0.4	1.1
Systolic blood pressure, automated reading	0.7	2.1	4.6	-2.1	-1.5	-1.0	-2.1	-1.8	-0.1	-0.7	-1.0
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	1.8	-0.7	-1.1	-0.6	-0.2	-1.2	1.4	0.1	-1.0
Financial difficulties in last 2 years	0.7	0.9	1.8	-0.1	1.0	1.2	1.1	1.0	-0.5	-0.6	1.3
Diabetes (self-reported)	0.7	1.1	3.1	0.7	1.0	0.4	1.8	0.9	0.2	-1.5	0.6
Neuroticism score	0.7	1.5	4.6	0.2	1.1	1.1	2.1	1.6	-0.1	-1.0	1.3
Hip circumference	0.7	2.9	6.6	-0.7	-1.4	-2.6	-1.1	-1.4	0.8	2.5	-2.1
Mouth/teeth dental problems: Dentures	0.7	1.1	2.3	0.2	1.5	0.7	0.9	1.2	-1.3	-0.4	1.3
Pulse wave Arterial Stiffness index	0.7	0.8	2.4	1.2	0.2	1.6	0.7	0.5	-1.2	-0.5	0.3
Gout (self-reported)	0.7	1.0	3.2	-1.8	-0.7	-1.0	-0.2	-0.8	1.2	-0.4	-0.8
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.6	-0.5	1.3	0.2	-0.2	1.2	-1.2	-0.3	1.2
Smoking status: Current	0.7	1.1	4.3	-1.2	-0.3	-0.8	-2.1	-1.0	-0.3	0.8	-0.4
Average weekly champagne plus white wine intake	0.7	0.9	2.4	-1.5	0.7	-0.0	1.1	0.7	-1.6	0.8	-0.2
Diastolic blood pressure, automated reading	0.7	2.2	4.6	-1.9	-1.3	-0.7	-2.1	-1.7	0.3	-1.9	-1.0
Cholesterol lowering medication	0.7	1.1	3.7	-1.9	-0.4	-1.3	-1.1	-0.9	0.6	-0.8	-0.4
Bipolar Disorder (2018)	0.6	0.9	2.3	0.9	1.4	1.2	0.0	0.0	0.0	0.8	1.5
Depression (Nagel 2018)	0.6	1.0	5.3	-0.9	0.2	-0.6	-0.6	-0.8	0.3	-2.3	0.5
Ulcerative Colitis (UC)	0.6	1.1	7.3	2.7	-0.5	0.7	-0.3	0.5	0.1	-0.6	-0.4
Primary Biliary Cirrhosis	0.6	0.8	3.4	1.9	-0.2	-0.1	-0.9	0.4	-0.5	1.5	-0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.7	1.1	1.2	0.2	1.6	1.2	-0.6	-1.1	0.9
Frequency of depressed mood in last 2 weeks	0.6	0.9	5.9	-0.0	0.4	0.2	0.4	-0.2	-0.3	-2.4	0.7
Relative age of first facial hair	0.6	1.2	3.3	-1.0	-0.3	-1.5	-1.8	-1.0	-0.4	-1.3	-0.6
Leg fat-free mass (left)	0.6	3.3	7.2	-2.7	-0.5	-2.5	0.1	-1.4	1.6	2.4	-1.4
Leg predicted mass (left)	0.6	3.3	7.8	-2.8	-0.5	-2.6	0.0	-1.4	1.6	2.3	-1.4
Qualifications: None of the above	0.6	1.3	2.6	1.2	0.3	1.4	0.4	0.7	-1.5	-1.6	1.3
Mouth/teeth dental problems	0.6	0.9	4.0	2.0	-0.7	0.3	0.2	-0.8	1.0	0.8	-0.3
Medication: Simvastatin	0.6	0.9	1.6	-1.1	-1.1	-1.1	-0.7	-1.2	0.8	-0.3	-0.7
Happiness	0.6	0.7	2.5	-1.6	-0.1	-0.9	-0.5	-1.3	-0.3	-0.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.1	-0.8	-0.8	-1.0	-1.0	-0.3	0.8	1.0	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	5.7	0.1	-1.5	-0.3	-0.5	-0.9	1.9	2.4	-1.4
Medication: Amlodipine	0.6	0.8	1.5	-0.8	-1.0	-1.0	-0.3	-0.7	1.2	0.8	-1.1
Number of children fathered	0.6	0.7	3.1	1.1	0.2	0.4	0.5	1.0	-0.2	-1.7	-0.3
Shortness of breath walking on level ground	0.6	0.7	3.7	-0.2	-0.4	-0.3	-0.2	-0.6	1.1	-1.9	-0.3
Pulse rate, automated reading	0.6	2.0	5.1	1.9	-0.1	2.1	-0.5	0.7	-0.7	-2.3	1.2
Alcohol intake frequency.	0.6	1.4	5.4	2.3	0.3	1.6	1.2	0.6	-0.3	-0.5	1.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	3.1	-1.0	1.1	0.2	-0.1	0.3	-1.8	0.5	0.7
Supplements: Vitamin C	0.6	0.7	2.0	0.2	-0.8	0.3	-1.2	-0.3	0.9	-1.4	-0.5
Illnesses of siblings: Diabetes	0.6	0.7	1.3	-0.3	-1.0	-1.1	-1.1	-0.1	0.8	-0.8	-1.0
Qualifications: nursing, teaching	0.6	0.9	3.0	-1.7	-0.3	-0.9	-0.3	-0.9	1.1	-0.2	-0.9
Commuting to job workplace: Walk	0.6	0.7	3.4	-1.9	-0.1	-1.1	0.3	-0.6	0.5	0.1	-0.4
Eye problems/disorders: Cataract	0.6	0.7	3.1	-1.8	-0.1	-0.7	-1.1	-0.5	0.1	-0.8	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.8	3.2	0.5	0.6	0.8	1.8	0.9	0.2	0.7	0.6
Ever taken oral contraceptive pill	0.6	0.6	2.0	0.4	0.9	0.8	0.6	0.3	-0.4	1.4	0.9
High cholesterol (Self-reported)	0.6	1.1	2.3	-1.5	-1.2	-1.1	-1.0	-0.9	0.7	-0.3	-1.1
Number of operations (self-reported)	0.6	1.0	2.5	-0.1	1.2	1.2	0.6	0.9	-1.6	-0.3	1.1
Alzheimer’s Disease (including proxy)	0.5	0.7	1.7	0.8	0.4	1.2	0.5	0.8	-0.7	-1.3	0.6
Verbal and Numeric Reasoning (VNR)	0.5	1.2	5.5	-2.4	0.9	-0.9	-0.3	1.1	0.1	1.1	-0.5
HbA1C	0.5	0.5	1.2	1.1	0.9	0.5	1.0	0.6	0.2	0.2	0.7
Neuroticism (2016)	0.5	0.7	2.0	0.2	0.5	0.2	1.2	1.4	0.3	-1.0	0.8
BMI	0.5	2.9	8.6	-1.3	-0.9	-2.9	-1.1	-1.6	-0.0	2.2	-1.8
Neuroticism	0.5	1.2	2.9	-0.3	1.0	0.6	1.4	1.2	-0.1	-1.7	1.1
Hand grip strength (left)	0.5	1.3	5.9	2.4	1.1	1.1	1.0	-0.2	-0.2	0.3	0.7
Ever had hysterectomy (womb removed)	0.5	0.6	1.6	-0.1	1.0	0.4	1.3	0.8	0.1	-0.7	0.7
Diabetes (mother)	0.5	0.6	3.3	0.8	-0.4	-0.1	-0.5	0.3	0.5	-1.8	-0.2
Current tobacco smoking	0.5	0.8	3.7	-1.1	-0.3	-0.6	-1.9	-1.0	-0.3	0.3	-0.3
Average weekly fortified wine intake	0.5	0.6	1.6	-0.6	-1.2	-0.8	-0.3	-0.6	-0.2	0.5	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	4.2	-0.4	0.6	0.2	-0.0	0.1	0.1	-2.0	0.9
Supplements: Glucosamine	0.5	0.7	2.0	-0.1	1.4	0.7	0.6	1.4	-0.4	-0.4	0.7
High blood pressure (mother)	0.5	0.6	1.9	-0.1	-0.4	-0.8	-0.6	-1.1	0.6	-1.4	-0.6
Waist circumference	0.5	1.8	5.0	-1.0	-1.2	-2.2	-1.0	-0.7	-0.1	1.9	-1.4
Medication: Ramipril	0.5	0.7	3.3	-1.8	0.4	-0.9	0.0	0.0	-0.7	0.7	-0.2
Fluid intelligence score	0.5	1.0	3.1	-1.8	1.4	-0.3	1.2	0.8	-0.4	0.7	0.2
Arm fat percentage (right)	0.5	2.1	4.7	1.8	1.1	0.4	0.9	2.1	-2.2	1.0	1.0
Medication: Lansoprazole	0.5	0.5	2.2	-0.8	0.5	-0.7	-0.2	0.7	-1.5	-0.1	0.2
Exposure to tobacco smoke at home	0.5	0.5	3.1	0.5	-0.2	0.0	0.3	-0.3	-0.8	1.8	-0.4
Blood clot in the leg (DVT)	0.5	0.7	1.1	-1.0	-1.1	-0.8	-0.8	-0.4	0.6	0.7	-1.0
Family relationship satisfaction	0.5	0.6	1.8	-0.5	-0.4	-1.3	0.1	-1.2	0.6	0.0	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	1.4	0.8	-0.6	-0.2	0.4	-0.7	1.2	0.6	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.2	-1.3	0.2	-0.2	0.8	0.3	-0.2	1.5	-0.1
Medication: Aspirin	0.5	0.6	2.8	-1.2	-0.0	-0.4	-0.1	0.4	-0.4	-1.7	-0.1
Medication: Gliclazide	0.5	0.5	1.2	0.4	1.1	0.4	1.0	0.8	-0.4	0.1	0.8
Mother’s age at death	0.5	0.7	1.5	1.2	1.0	0.8	0.7	0.8	-0.7	-0.6	0.5
Financial situation satisfaction	0.5	0.6	2.7	-1.1	-0.2	-0.5	0.1	-0.2	0.6	-1.6	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.4	-0.7	-1.2	-0.7	-0.8	-0.4	0.7	0.6	-1.1
Blood Eosinophil Count	0.4	3.2	14.1	0.3	-1.1	-0.5	-3.8	-0.3	-1.9	-2.5	0.0
Heel T-Score	0.4	3.5	8.5	0.2	-0.6	-2.9	-0.6	-1.4	2.1	-2.9	-1.9
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.5	-0.6	0.0	-1.2	-0.3	-1.0	0.4	0.7	-0.5
Medication for hormone replacement therapy	0.4	0.4	1.9	-0.5	0.0	-0.5	-0.8	0.1	1.4	0.7	-0.1
Supplements: Zinc	0.4	0.4	0.8	0.6	0.7	0.9	0.5	0.2	0.6	-0.8	0.8
Trunk fat percentage	0.4	1.7	7.1	2.7	0.3	0.1	0.4	1.4	-1.4	1.4	0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.5	0.7	-0.5	-0.2	-0.3	0.0	0.3	-1.6	-0.3
Hair/balding pattern: Pattern 2	0.4	0.5	2.5	-0.3	0.3	0.6	0.3	1.6	-0.7	0.2	0.6
Had menopause	0.4	0.5	1.4	0.9	0.5	0.2	-0.0	1.0	0.2	1.2	0.5
Weight	0.4	2.1	6.7	-0.9	-0.9	-2.0	-0.1	-1.0	1.1	2.6	-1.4
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.2	0.9	-1.1	0.1	0.0	-0.4	1.9	2.1	-1.0
Pulse rate	0.4	0.7	2.1	0.7	-0.6	1.2	-1.5	0.4	-0.6	-0.7	0.6
Peak expiratory flow (PEF)	0.4	0.9	2.0	0.0	-0.6	-1.0	-0.8	-1.4	1.4	1.2	-0.5
Pulse wave reflection index	0.4	0.5	1.4	0.8	-0.2	0.6	1.2	-0.3	-0.9	-0.5	-0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	3.2	-1.8	0.6	-0.1	0.5	0.1	-0.6	-0.5	0.4
Exposure to tobacco smoke outside home	0.4	0.5	1.0	-1.0	-0.6	-0.6	0.1	-0.8	0.7	-0.9	-0.5
Comparative height size at age 10	0.4	2.4	9.5	0.2	-1.1	-0.3	0.2	-0.9	2.6	3.1	-0.9
Medication: Aspirin	0.4	0.5	3.4	-0.8	-0.3	-0.2	-0.1	0.3	-0.3	-1.8	-0.3
Arm fat percentage (left)	0.4	1.5	3.3	1.5	1.0	0.1	0.7	1.8	-1.8	1.0	0.8
Ever had bowel cancer screening	0.4	0.5	1.0	-0.6	-0.8	-0.8	-0.8	-0.1	0.3	0.7	-1.0
Friendships satisfaction	0.4	0.5	1.6	-1.2	-0.1	-1.0	0.6	-0.6	-0.1	-0.4	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.4	-1.2	-0.5	-0.8	-0.0	0.0	1.2	0.0	-0.9
Back pain experienced in last month	0.4	0.6	1.9	-0.4	0.2	-0.7	-1.2	0.7	-1.4	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.8	-1.3	-1.1	-0.1	-0.9	-0.2	0.8	1.4	-0.5
Wears glasses or contact lenses	0.4	0.5	1.8	0.5	0.6	-0.1	-0.7	-0.2	-1.3	0.5	0.7
Hearing aid user	0.4	0.4	1.3	-1.1	0.1	0.6	0.3	0.6	-0.6	-0.8	0.7
Commuting to job workplace: Public transport	0.4	0.4	1.1	-0.7	0.1	-0.7	-1.1	0.0	-0.3	1.0	-0.3
Medication: Atorvastatin	0.4	0.6	1.3	-1.1	0.5	0.4	-0.4	0.2	-1.1	-0.9	0.8
Leg fat percentage (left)	0.4	1.5	3.4	0.7	-1.9	-1.7	-1.5	-0.7	0.1	0.1	-1.6
Average weekly beer plus cider intake	0.4	0.6	1.4	-0.9	-0.8	-1.2	-0.5	-1.0	0.7	0.2	-0.7
Risk taking	0.4	0.5	1.7	-0.8	-0.2	-0.5	-1.3	-1.0	-0.6	0.3	-0.2
Age started oral contraceptive pill	0.4	0.5	1.2	0.8	0.6	0.1	1.1	0.9	0.8	-0.1	0.1
Unable to work because of sickness or disability	0.4	0.5	1.5	0.2	0.2	0.5	-1.2	0.9	-0.9	-0.5	0.6
Myopia	0.4	0.6	2.0	0.6	0.1	-0.7	0.8	0.5	1.4	1.0	-0.3
Leg fat mass (left)	0.4	1.4	3.5	0.2	-1.5	-1.9	-0.8	-0.8	0.5	1.2	-1.6
Worry (Nagel 2018)	0.3	0.7	1.8	-0.2	0.6	0.7	1.2	0.8	0.2	-1.3	0.8
Alzheimer’s Disease (in mother)	0.3	0.4	1.2	0.0	-0.3	-1.0	-0.3	-0.5	1.1	0.3	-0.8
Irritable Bowel Disease (IBD)	0.3	0.6	2.6	1.6	-0.8	0.1	-0.6	0.2	0.9	-0.0	-0.8
Reaction Time	0.3	0.6	1.5	-0.4	-1.2	-0.7	-1.2	-0.5	0.1	-0.6	-0.9
Blood Platelet Count	0.3	3.4	13.1	3.6	0.1	2.9	0.1	0.1	-2.2	0.1	1.1
Blood White Count	0.3	2.5	6.2	-1.4	-1.6	-1.0	-2.5	-2.4	-1.0	-0.3	-1.4
Maternal smoking around birth	0.3	0.4	1.1	-0.3	0.6	0.4	0.6	0.3	-0.7	1.1	0.9
Sitting height	0.3	2.3	8.5	1.6	0.1	0.7	2.1	-0.8	2.9	1.3	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	-1.5	-0.2	-0.8	0.0	-0.4	1.0	-0.2	-0.2
Forced vital capacity (FVC)	0.3	1.2	3.8	0.6	-1.0	0.3	0.2	-0.2	1.7	2.0	-1.1
Allergy	0.3	0.6	1.5	-0.3	-0.8	-1.0	-1.0	-1.2	0.2	-0.7	-0.7
Pain all over the body in last month	0.3	0.3	1.2	1.1	-0.0	-0.2	-0.2	-0.3	0.5	0.8	0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.9	-0.9	0.7	0.3	-0.3	-0.0	-0.9	0.9	0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.7	1.6	-0.7	1.0	0.4	0.1	-0.1	-1.1	1.2	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.3	-0.2	-0.2	-0.9	-0.6	-0.2	1.1	0.1	-0.3
Medication: Cholesterol lowering	0.3	0.4	1.6	-1.3	-0.6	-0.4	-0.2	-0.7	-0.3	-0.4	-0.6
Illnesses of mother	0.3	0.4	1.3	0.3	0.2	0.5	0.7	0.0	-1.1	1.0	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	-0.7	0.6	-0.2	1.2	0.7	-0.3	-0.5	0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	0.9	0.9	0.9	0.2	0.3	0.7	-0.0	0.7	0.9
Forced vital capacity (FVC), Best measure	0.3	0.9	4.2	0.4	-0.8	0.5	0.3	-0.2	1.1	2.1	-0.8
Body fat percentage	0.3	1.2	5.7	2.4	0.1	-0.0	0.2	1.2	-1.3	1.0	0.1
Comparative body size at age 10	0.3	0.7	2.3	-0.2	-1.1	-0.8	-0.0	-1.5	0.9	0.3	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	-0.2	0.7	0.7	1.0	0.8	-0.2	0.0	0.7
Medication: Blood pressure	0.3	0.6	1.4	-0.9	-1.1	-0.4	0.0	-0.7	0.7	-0.7	-1.2
Medication: Allopurinol	0.3	0.3	1.4	-1.2	-0.1	-0.7	0.2	-0.3	0.7	-0.2	-0.1
Medication: Seretide 50 evohaler	0.3	0.3	0.8	-0.9	0.7	-0.4	0.5	0.0	0.4	-0.8	0.2
Leg pain on walking	0.3	0.4	1.3	-0.1	-0.4	-0.4	-0.9	-0.6	-0.7	-1.1	-0.3
Long-standing illness, disability or infirmity	0.3	0.5	1.8	-1.3	0.5	-0.3	0.3	1.1	0.0	-0.5	0.2
Mineral and other dietary supplements	0.3	0.4	0.6	-0.8	-0.8	-0.5	0.4	-0.6	0.7	-0.6	-0.6
Alcohol drinker status: Never	0.3	0.4	1.1	0.8	-0.6	0.1	-0.3	0.1	1.0	-0.8	-0.2
Irritability	0.3	0.5	1.0	-0.7	0.9	0.3	1.0	0.1	-0.9	-0.3	0.9
Crohns Disease (2017)	0.2	0.4	0.9	-0.1	-0.8	-0.3	-0.6	-0.5	1.0	-0.3	-0.8
Body Mass Index (BMI) (2010)	0.2	0.3	1.4	0.2	-0.6	-0.4	0.2	-0.4	1.2	0.2	-0.2
HDL Cholesterol	0.2	0.4	1.4	0.4	1.0	0.3	-0.4	0.0	-1.2	-0.1	0.6
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.4	0.6	0.6	0.3	0.0	0.6	0.0	0.5	0.3
Ulcerative Colitis	0.2	0.3	2.0	1.4	0.0	0.5	0.0	0.4	0.0	-0.2	0.2
Waist Hip Ratio (WHR)	0.2	0.8	3.5	-0.0	0.5	0.8	-0.8	0.6	-1.9	0.2	1.0
Lung FVC	0.2	1.0	4.5	0.8	-0.2	2.1	1.0	1.1	-0.3	0.5	0.3
Tanning	0.2	2.2	13.8	3.7	-0.0	0.8	-0.8	-0.4	0.6	-1.4	0.3
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.4	-0.6	-0.5	-0.6	-0.4	-0.1	0.7	0.3	-0.6
Medication: Metformin	0.2	0.3	1.1	-0.2	0.4	-0.7	0.5	0.1	-0.1	1.1	-0.3
Hand grip strength (right)	0.2	0.7	3.3	1.8	0.2	0.4	0.6	-0.9	0.6	0.6	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.5	1.1	1.0	-0.5	-0.3	0.5	-0.4	-1.2	-0.0
Medication: Atenolol	0.2	0.3	0.8	-0.3	-0.6	-0.0	-0.8	-0.3	0.4	-0.9	-0.4
Trunk fat mass	0.2	0.9	4.1	1.4	-0.3	-0.8	0.2	0.3	-0.2	2.0	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.1	1.1	0.4	-0.8	-0.6	0.1	-0.0	-0.9	-0.7
Time employed in main current job	0.2	0.2	1.1	-0.5	0.0	0.0	-1.1	0.3	-0.4	0.4	0.1
Worrier / anxious feelings	0.2	0.3	0.9	-0.8	-0.1	0.2	0.7	0.9	0.6	-0.1	0.0
Noisy workplace	0.2	0.2	0.8	-0.9	0.4	0.2	0.1	0.7	-0.4	-0.1	0.4
Prospective memory result	0.2	0.2	0.5	0.1	0.4	0.3	-0.5	0.4	-0.6	-0.7	0.4
Arm fat mass (right)	0.2	0.7	2.9	0.4	0.5	-0.7	0.3	0.9	-0.9	1.7	-0.0
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-0.5	0.6	0.8	1.0	0.2	0.9	-0.9	0.4
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.3	1.1	-0.2	0.4	0.7	-0.2	0.4	-0.1	-0.1
Leg fat percentage (right)	0.2	0.8	2.2	1.5	-1.2	-0.8	-0.8	0.2	-0.6	0.0	-0.9
Wheeze or whistling in the chest in last year	0.2	0.4	1.3	-0.8	0.7	-0.0	-0.3	0.2	-1.2	-0.4	0.2
Qualifications: College or University degree	0.2	0.5	1.4	-0.2	0.6	-1.2	-0.1	-0.0	0.8	1.2	-0.5
Medication for pain relief, constipation, heartburn	0.2	0.4	1.4	1.2	0.1	0.4	-0.2	-0.8	0.3	0.8	0.0
Medication: Ibuprofen	0.2	0.3	1.6	0.4	0.2	-0.6	-0.1	0.0	1.3	0.2	-0.2
Heart disease (mother)	0.2	0.2	0.6	-0.4	0.3	-0.7	-0.0	-0.4	0.8	-0.3	-0.3
Whole body fat mass	0.2	0.9	3.6	1.2	-0.6	-1.1	-0.1	0.1	-0.1	1.9	-0.9
Leg fat mass (right)	0.2	0.8	1.8	0.6	-1.1	-1.4	-0.4	-0.2	0.0	1.2	-1.3
Suffer from ‘nerves’	0.2	0.3	1.1	-0.2	0.3	0.3	0.7	0.4	1.1	0.4	0.2
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.1	0.5	0.0	-0.1	-0.6	-0.1	-0.1	1.1	-0.2
Fractured/broken bones in last 5 years	0.2	0.3	1.4	0.1	0.2	0.4	-0.4	-0.5	0.1	-1.2	0.6
Pain experienced in last month	0.2	0.4	1.3	0.6	0.1	0.4	0.6	-0.2	1.1	-0.7	0.2
Breast Cancer	0.1	0.3	1.2	0.3	0.2	0.6	0.1	0.9	-1.1	0.0	0.5
Respiratory disease	0.1	0.2	0.6	-0.8	0.5	-0.5	-0.1	0.0	-0.5	-0.3	-0.2
Vitamin and mineral supplements	0.1	0.1	0.6	-0.3	-0.1	0.0	0.8	0.2	0.0	0.2	0.4
Body mass index (BMI)	0.1	0.6	1.8	-1.1	0.0	-1.3	-0.4	0.4	-1.0	0.6	-0.2
Asthma	0.1	0.1	0.6	0.1	0.4	0.3	0.3	0.1	-0.7	0.4	-0.2
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.6	0.1	0.1	0.2	-0.2	-0.6	-0.4	-0.8	-0.1
Chest pain or discomfort	0.1	0.2	0.8	-0.6	-0.2	0.4	0.1	0.3	0.2	0.9	0.2
Had major operations	0.1	0.1	0.5	0.1	-0.5	0.1	-0.7	-0.4	-0.5	0.2	0.0
Asthma (self-reported)	0.1	0.1	0.4	-0.3	0.2	0.2	0.2	0.1	-0.7	0.5	-0.3
Osteoporosis (self-reported)	0.1	0.1	0.2	0.0	0.2	0.2	0.4	-0.1	0.2	0.5	0.5
Arm fat mass (left)	0.1	0.5	2.2	0.1	0.1	-1.1	0.0	0.6	-0.5	1.5	-0.3
Commuting to job workplace: Cycle	0.1	0.2	0.8	-0.1	0.2	-0.0	0.4	0.4	-0.5	0.9	-0.2
Alcohol drinker status: Previous	0.1	0.1	0.3	-0.1	0.3	-0.0	-0.3	0.4	-0.6	0.2	0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.5	2.7	-0.6	-0.5	-0.0	1.6	-0.2	-0.2	0.5	-0.2
Average weekly red wine intake	0.0	0.1	0.2	-0.3	0.4	-0.4	-0.3	-0.3	-0.1	0.1	0.0

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