[Hub]/) : Traits : Impedance of leg (right) : ← →

chr1:24,871,730-26,855,401

Best TWAS P=1.34e-08 · Best GWAS P=1.65e-07 conditioned to 0.00827

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Breast Mammary Tissue (Male)	MTFR1L	0.11	0.00	enet	18	-0.01	4.6e-01	1.5	5.7	1.3e-08	-0.53	0.04	0.30	TRUE
7	GTEx	Testis	TMEM57	0.25	0.11	enet	17	0.12	7.4e-06	-5.1	5.5	4.0e-08	-0.85	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM50A	0.08	0.02	blup	7	0.02	1.5e-03	-5.2	5.4	7.5e-08	-0.96	0.00	0.66	FALSE
20	The Cancer Genome Atlas	Glioblastoma Multiforme	RHCE	0.13	0.02	blup	18	0.04	3.0e-02	-5.2	5.4	8.5e-08	-0.97	0.01	0.38	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	LDLRAP1	0.03	0.01	blup	21	0.01	9.5e-03	-5.1	5.3	8.6e-08	-0.79	0.00	0.70	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	RHCE	0.06	0.05	blup	18	0.03	2.4e-03	-5.2	5.3	9.3e-08	-0.97	0.01	0.95	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	RHCE	0.22	0.11	enet	6	0.12	5.1e-12	-5.1	5.3	1.1e-07	-0.97	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RHCE	0.09	0.05	enet	3	0.04	2.4e-03	-5.2	5.3	1.2e-07	-0.97	0.01	0.86	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	RHCE	0.38	0.20	lasso	3	0.22	4.9e-24	-5.2	5.3	1.2e-07	-0.96	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	RHCE	0.20	0.13	enet	8	0.10	3.7e-06	-5.2	5.3	1.4e-07	-0.99	0.01	0.98	FALSE
38	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RHCE	0.29	0.03	blup	17	0.01	2.0e-01	-5.2	5.3	1.4e-07	-0.97	0.01	0.51	FALSE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	TMEM57	0.06	0.03	enet	6	0.02	1.5e-02	-5.1	5.2	1.5e-07	-0.95	0.01	0.56	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TMEM50A	0.07	0.02	blup	7	0.02	1.3e-02	-5.2	5.2	1.6e-07	-0.96	0.00	0.54	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	RHCE	0.13	0.08	lasso	3	0.08	1.3e-16	-5.2	5.2	1.6e-07	-0.99	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TMEM50A	0.10	0.04	enet	3	0.04	6.1e-03	-5.2	5.2	1.6e-07	-1.00	0.00	0.76	FALSE
3	GTEx	Artery Aorta	TMEM57	0.14	0.15	enet	10	0.14	3.3e-08	-5.0	5.2	1.7e-07	-0.94	0.02	0.98	FALSE
4	GTEx	Breast Mammary Tissue	RP11-335G20.7	0.23	0.10	enet	5	0.09	2.4e-05	-5.2	-5.2	1.7e-07	0.97	0.02	0.98	FALSE
34	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RHCE	0.18	0.14	lasso	2	0.15	3.6e-10	-5.2	5.2	1.7e-07	-0.99	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RHCE	0.12	0.08	lasso	3	0.07	7.8e-04	-5.2	5.2	1.7e-07	-1.00	0.01	0.81	FALSE
37	The Cancer Genome Atlas	Rectum Adenocarcinoma	RHCE	0.23	0.04	blup	17	0.04	4.4e-02	-5.2	5.2	1.7e-07	-0.98	0.00	0.22	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RHCE	0.29	0.34	lasso	4	0.34	2.0e-42	-5.2	5.2	1.8e-07	-0.98	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RHCE	0.41	0.23	enet	8	0.22	3.1e-08	-5.1	5.2	1.8e-07	-0.98	0.01	0.98	FALSE
2	CommonMind	Brain Pre-frontal Cortex	TMEM50A	0.32	0.37	lasso	8	0.37	6.9e-47	-5.2	5.2	1.9e-07	-0.98	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TMEM50A	0.02	0.02	lasso	1	0.02	5.2e-03	-5.2	5.2	1.9e-07	-0.99	0.00	0.54	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM57	0.06	0.02	lasso	3	0.02	2.3e-05	-5.2	5.2	2.0e-07	-0.97	0.01	0.98	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	RHCE	0.16	0.07	blup	18	0.07	8.0e-09	-5.1	5.2	2.0e-07	-0.98	0.01	0.98	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	TMEM57	0.07	0.04	lasso	3	0.05	9.1e-07	-4.9	5.2	2.1e-07	-0.90	0.02	0.97	FALSE
33	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM57	0.02	0.00	blup	20	0.00	2.0e-01	-4.9	5.2	2.1e-07	-0.96	0.01	0.43	FALSE
8	GTEx	Thyroid	TMEM50A	0.19	0.11	lasso	2	0.08	2.0e-06	-5.2	-5.2	2.2e-07	0.99	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RHD	0.07	0.01	blup	7	0.01	6.6e-02	-5.2	-5.2	2.2e-07	0.93	0.00	0.38	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	TMEM50A	0.11	0.03	lasso	2	0.03	1.9e-04	-5.1	5.2	2.2e-07	-0.97	0.00	0.92	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RHCE	0.09	0.06	blup	18	0.06	1.3e-07	-5.1	5.2	2.2e-07	-0.97	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TMEM57	0.04	0.02	blup	20	0.01	3.9e-02	-5.1	5.2	2.2e-07	-0.96	0.01	0.64	FALSE
6	GTEx	Cells Transformed fibroblasts	C1orf63	0.09	0.04	lasso	5	0.03	2.5e-03	-5.1	-5.2	2.3e-07	0.95	0.02	0.97	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	RHCE	0.29	0.36	lasso	7	0.35	6.3e-47	-5.1	5.2	2.4e-07	-0.97	0.02	0.98	FALSE
10	GTEx	Whole Blood	TMEM50A	0.08	0.07	lasso	2	0.07	4.7e-07	-5.2	-5.2	2.5e-07	0.99	0.01	0.98	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RHCE	0.06	0.05	blup	18	0.05	1.4e-06	-5.1	5.2	2.6e-07	-0.98	0.01	0.98	FALSE
9	GTEx	Uterus	TMEM50A	0.29	0.11	enet	15	0.04	6.0e-02	-2.9	-5.1	2.9e-07	0.71	0.03	0.65	FALSE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RHCE	0.10	0.03	blup	18	0.03	1.1e-03	-5.1	5.1	3.0e-07	-0.97	0.01	0.94	FALSE
29	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RHCE	0.21	0.15	blup	18	0.18	6.3e-09	-5.1	5.1	3.0e-07	-0.92	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RHCE	0.15	0.03	blup	18	0.03	1.3e-04	-5.1	5.1	3.1e-07	-0.98	0.01	0.96	FALSE