Hub : Genes

TMEM50A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3210 0.0420 0.0e+00 0.373 0.322 0.362 0.365 0.367 9.3e-48 4.1e-40 4.7e-46 1.6e-46 6.9e-47
2 GTEx Adrenal Gland 0.3115 0.0764 2.7e-05 0.177 NA 0.114 NA 0.059 6.0e-07 NA 7.2e-05 NA 3.6e-03
3 GTEx Artery Tibial 0.1465 0.0559 1.1e-03 0.001 NA 0.005 NA 0.007 2.4e-01 NA 1.1e-01 NA 8.8e-02
4 GTEx Cells Transformed fibroblasts 0.3600 0.0550 1.3e-15 0.211 NA 0.284 NA 0.262 8.9e-16 NA 1.8e-21 NA 1.0e-19
5 GTEx Esophagus Muscularis 0.1680 0.0600 3.2e-04 0.047 NA 0.064 NA 0.083 7.6e-04 NA 1.0e-04 NA 9.1e-06
6 GTEx Heart Atrial Appendage 0.3420 0.1120 5.4e-03 0.058 NA 0.013 NA -0.003 1.4e-03 NA 7.9e-02 NA 4.8e-01
7 GTEx Lung 0.1358 0.0522 2.1e-03 0.036 NA 0.005 NA 0.000 8.3e-04 NA 1.3e-01 NA 2.9e-01
8 GTEx Nerve Tibial 0.1001 0.0382 3.7e-03 0.017 NA 0.022 NA 0.032 2.0e-02 NA 9.9e-03 NA 2.6e-03
9 GTEx Skin Sun Exposed Lower leg 0.1280 0.0350 4.6e-06 0.136 NA 0.109 NA 0.107 2.4e-11 NA 2.6e-09 NA 3.9e-09
10 GTEx Spleen 0.3450 0.1200 9.8e-03 0.088 NA 0.058 NA 0.111 2.9e-03 NA 1.4e-02 NA 8.9e-04
11 GTEx Thyroid 0.1880 0.0570 4.8e-05 0.108 NA 0.040 NA 0.076 1.4e-08 NA 4.9e-04 NA 2.1e-06
12 GTEx Uterus 0.2860 0.1070 6.2e-03 0.111 NA 0.038 NA 0.011 3.0e-03 NA 6.0e-02 NA 1.9e-01
13 GTEx Whole Blood 0.0810 0.0360 9.1e-03 0.073 NA 0.051 NA 0.070 3.0e-07 NA 1.6e-05 NA 4.7e-07
14 NTR Blood 0.2159 0.0299 0.0e+00 0.044 0.128 0.167 0.162 0.173 4.5e-14 3.6e-39 1.5e-51 6.4e-50 1.8e-53
15 ROSMAP Brain Pre-frontal Cortex 0.0473 0.0208 3.3e-03 0.000 0.009 -0.002 0.011 -0.002 3.0e-01 2.1e-02 6.5e-01 1.2e-02 7.1e-01
16 YFS Blood 0.3692 0.0405 0.0e+00 0.143 0.165 0.190 0.189 0.169 2.2e-44 1.0e-51 8.7e-60 1.1e-59 7.3e-53
17 TCGA Bladder Urothelial Carcinoma 0.0690 0.0520 1.4e-03 0.019 0.017 0.015 NA 0.015 8.4e-03 1.3e-02 1.9e-02 NA 1.8e-02
18 TCGA Breast Invasive Carcinoma 0.1068 0.0511 6.7e-13 0.029 0.032 0.028 NA 0.029 8.5e-07 2.8e-07 1.5e-06 NA 1.3e-06
19 TCGA Cervical Squamous Cell Carcinoma 0.1040 0.0720 8.6e-04 0.042 0.028 0.037 NA 0.036 3.7e-03 1.5e-02 6.1e-03 NA 7.1e-03
20 TCGA Colon Adenocarcinoma 0.2800 0.1240 1.5e-07 0.054 0.049 0.053 NA 0.033 4.4e-04 8.3e-04 4.9e-04 NA 5.1e-03
21 TCGA Head and Neck Squamous Cell Carcinoma 0.0788 0.0488 8.4e-05 0.018 0.022 0.018 NA 0.014 4.0e-03 1.5e-03 4.0e-03 NA 8.4e-03
22 TCGA Kidney Renal Clear Cell Carcinoma 0.0237 0.0205 9.1e-03 0.020 0.012 0.011 NA 0.016 2.3e-03 1.5e-02 1.7e-02 NA 5.2e-03
23 TCGA Lung Adenocarcinoma 0.1122 0.0626 9.4e-07 0.029 0.028 0.025 NA 0.030 2.2e-04 2.7e-04 5.9e-04 NA 1.9e-04
24 TCGA Lung Squamous Cell Carcinoma 0.1484 0.0757 2.4e-10 0.047 0.038 0.046 NA 0.041 4.1e-06 3.7e-05 5.0e-06 NA 1.7e-05
25 TCGA Soft Tissue Sarcoma 0.1400 0.0790 1.8e-05 0.050 0.014 0.044 NA 0.000 6.4e-04 4.7e-02 1.2e-03 NA 3.1e-01
26 TCGA Stomach Adenocarcinoma 0.1460 0.0800 3.3e-04 0.011 0.013 0.003 NA 0.006 5.0e-02 3.4e-02 1.7e-01 NA 1.1e-01
27 TCGA Testicular Germ Cell Tumors 0.3110 0.1260 1.0e-04 0.054 0.030 0.038 NA 0.036 5.6e-03 3.1e-02 1.7e-02 NA 2.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bipolar Disorder (2018) 0.4 0.6 4.7 0.3 -0.6 0.0 0.2 -0.5 1.9 -0.1 0.0 -0.3 -0.1 -0.3 -0.4 0.0 1.5 0.8 2.2 0.2 -0.5 0.4 -0.3 0.3 0.4 0.6 0.2 -0.3 -1.2 0.1
Bipolar Disorder or Schizophrenia 0.4 1.1 4.7 -0.8 0.4 -0.2 1.0 0.1 1.6 1.2 0.7 0.7 1.0 0.7 0.2 0.0 1.8 1.1 2.2 -0.9 -1.3 -0.5 -1.3 -0.8 -0.6 -0.5 -0.8 -1.1 -1.7 -1.1
Depressed Affect (Nagel 2018) 0.2 0.4 3.6 0.1 0.1 1.2 0.2 0.1 0.7 -0.5 -0.1 -0.3 -0.9 -0.3 -0.8 -0.3 0.9 -0.9 1.9 0.2 -0.5 0.3 -0.1 0.3 0.4 0.3 -0.0 -0.5 -1.0 0.0
Depression (Nagel 2018) 0.1 0.2 1.3 0.2 -0.3 -0.2 -0.2 -0.1 -0.2 -0.5 -0.3 -0.1 -0.5 -0.3 -1.2 -0.3 -0.0 0.1 1.0 0.4 -0.1 0.3 0.3 0.5 0.2 0.4 0.3 -0.1 -0.4 0.7
Intelligence (Savage-Jansen 2018) 1.3 4.0 7.6 2.2 -2.8 -1.7 -2.0 -0.7 -1.3 -1.8 -1.4 -1.9 -2.3 -1.9 -2.7 -2.0 -1.5 2.2 0.3 2.3 1.9 2.0 2.2 2.3 1.9 2.2 2.4 1.9 1.5 2.6
Neuroticism (Nagel 2018) 0.2 0.5 2.5 0.8 -0.8 1.0 -0.6 -0.2 0.3 -0.3 -0.5 -0.8 -0.7 -0.8 -1.1 -0.8 0.0 -0.4 1.6 0.8 0.4 0.9 0.5 0.9 0.8 0.9 0.7 0.4 -0.1 0.6
Schizophrenia (2018) 0.6 1.2 2.3 -1.2 1.0 0.0 1.2 0.6 0.5 1.5 1.1 1.2 1.3 1.1 0.4 1.0 1.1 0.7 1.1 -1.3 -1.2 -1.0 -1.4 -1.3 -1.0 -1.1 -1.2 -1.2 -1.2 -1.5
Schizophrenia vs Biploar Disorder 0.5 0.7 4.1 -0.9 0.9 0.0 1.4 1.1 0.0 0.8 1.0 1.1 2.0 1.1 0.4 0.0 0.0 0.2 0.8 -1.0 -0.5 -1.0 0.0 -1.1 -1.1 -0.9 0.0 0.0 -0.0 0.0
Worry (Nagel 2018) 1.0 2.1 6.1 1.9 -1.8 0.1 -1.3 -0.9 0.4 -1.1 -1.2 -1.7 -1.5 -1.8 -1.6 -1.7 0.0 0.4 2.5 1.6 1.0 1.9 1.2 1.7 1.8 1.9 1.6 1.1 0.3 1.3
Alzheimer’s Disease (in mother) 2.5 2.9 7.8 2.2 -2.0 -1.9 -1.6 -1.6 -0.7 -2.4 -1.8 -1.8 -1.4 -1.6 -2.8 -1.7 -0.1 0.6 1.4 1.9 1.1 1.9 1.4 2.0 1.8 2.0 1.8 1.1 0.3 1.9
Alzheimer’s Disease (in father) 0.3 0.3 1.3 -0.4 0.5 0.8 -0.4 0.5 0.2 0.6 0.7 0.4 0.8 0.4 0.7 0.3 -0.3 -0.3 -1.1 -0.5 0.1 -0.5 -0.2 -0.6 -0.4 -0.5 -0.4 0.1 0.6 -0.5
Alzheimer’s Disease (including proxy) 1.1 1.5 3.7 1.6 -1.4 -1.6 -1.8 -0.6 -0.4 -1.9 -0.9 -1.2 -0.7 -1.1 -1.9 -1.2 -0.6 0.4 0.1 1.4 1.1 1.3 1.2 1.3 1.2 1.4 1.4 1.1 0.9 1.4
Crohns Disease (2017) 0.1 0.2 1.2 -0.0 0.3 0.6 0.1 -1.0 -0.4 0.2 -0.5 0.0 -0.0 0.1 -1.1 -0.2 0.4 0.0 -0.3 0.2 -0.5 0.1 -0.0 0.3 0.1 0.2 -0.0 -0.4 -0.9 0.3
Irritable Bowel Disease (IBD) 0.1 0.3 1.8 -0.2 0.2 0.8 -0.3 -0.7 -0.4 -0.3 -0.2 0.2 0.3 0.2 -1.4 -0.1 0.5 0.6 -0.3 0.1 -0.7 -0.0 -0.0 0.3 0.0 -0.0 -0.2 -0.8 -1.2 0.4
Ulcerative Colitis (UC) 0.3 0.5 1.8 -0.8 0.4 1.2 -0.2 0.2 -0.1 0.1 0.6 0.9 0.8 0.8 -0.5 0.6 0.6 0.7 -0.1 -0.5 -1.1 -0.7 -0.5 -0.4 -0.7 -0.8 -0.9 -1.2 -1.3 -0.2
Major Depression (MDD) 5.8 7.0 12.9 -2.8 2.9 2.1 2.9 2.2 3.0 1.7 2.5 2.5 2.6 2.6 3.1 0.0 2.8 -1.8 1.2 -3.2 -2.9 -2.6 -3.4 -3.2 -2.6 -2.6 -2.9 -2.7 -2.6 -3.6
Reaction Time 0.2 0.4 3.2 0.1 -0.2 -0.5 0.8 -0.8 0.4 0.6 -0.4 0.0 0.2 -0.1 -0.1 -0.0 1.8 0.0 1.6 -0.2 -0.6 0.2 -0.5 -0.1 0.2 0.2 -0.2 -0.5 -1.1 -0.4
Verbal and Numeric Reasoning (VNR) 1.6 3.8 8.6 2.2 -2.7 -1.9 -2.2 -1.5 -1.3 -1.8 -1.3 -1.9 -2.1 -1.7 -2.9 -1.9 -1.2 2.6 0.8 2.2 1.6 2.0 2.1 2.3 1.9 2.0 2.0 1.6 1.1 2.4
Breast Cancer 1.7 4.0 7.5 2.1 -1.8 -2.7 -1.4 -1.2 -0.7 -2.0 -1.4 -2.0 -2.3 -2.2 -1.8 -2.0 -2.4 -0.8 -1.4 2.3 2.2 2.1 2.4 2.3 2.0 2.0 2.3 2.0 2.0 2.4
Ovarian Cancer 0.2 0.3 1.2 0.7 -0.3 0.9 -0.4 0.0 0.2 -0.4 -0.2 -0.8 -1.1 -0.8 0.1 -0.7 0.5 -1.1 0.2 0.4 0.4 0.8 0.3 0.4 0.8 0.7 0.5 0.5 0.1 0.1
Prostate Cancer 2.3 3.2 6.4 2.0 -1.8 -2.4 -2.5 -1.0 -2.2 -2.2 -1.6 -1.6 -0.4 -1.7 -1.6 -1.7 -1.7 -0.2 -0.3 2.0 1.9 1.9 1.9 2.0 1.7 2.0 2.2 1.8 1.7 2.1
Age at First Birth 0.5 0.8 3.2 1.2 -0.6 -0.9 -1.2 -0.9 -1.8 0.3 -1.6 -0.9 -0.7 -0.9 -1.5 0.0 -1.6 -1.1 -1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Bipolar Disorder (2011) 0.0 0.0 0.7 -0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.1 0.2 1.3 0.2 -0.3 0.2 -0.6 0.8 -0.4 -0.3 0.2 -0.2 0.2 -0.2 -0.0 0.0 -1.1 0.1 -1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Coronary Artery Disease (CAD) 0.2 0.2 1.2 0.4 -0.8 -0.6 -0.8 0.0 -0.3 0.1 -0.5 -0.1 -1.1 -0.5 -0.6 0.0 -1.0 -0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.2 0.3 1.8 -0.6 0.6 0.0 0.4 -0.9 0.2 1.4 0.5 0.4 -0.0 0.4 -0.0 0.0 0.6 0.8 -0.2 -0.5 -0.6 -0.4 -0.6 -0.5 -0.3 -0.4 -0.6 -0.5 -0.6 -0.6
Mean Putamen Volume 1.5 1.7 4.2 -1.5 1.1 0.4 0.8 2.0 1.0 1.3 1.9 1.6 0.9 1.5 2.0 1.3 -0.2 0.8 -1.1 -1.5 -0.6 -1.4 -1.0 -1.5 -1.4 -1.6 -1.2 -0.8 0.2 -1.5
Fasting Glucose 0.1 0.1 2.2 -0.0 -0.1 0.3 -0.2 -0.2 -0.2 0.4 0.0 0.1 -0.5 -0.0 -0.6 -0.0 0.3 -0.1 1.5 -0.0 -0.3 0.1 -0.2 0.0 0.1 0.1 -0.1 -0.3 -0.5 -0.2
HbA1C 1.0 1.1 3.7 1.1 -1.6 -1.4 -0.3 -0.5 1.0 -1.3 -0.9 -0.4 -0.2 -0.9 -0.0 -0.9 1.2 1.0 1.4 -0.3 -1.3 0.4 -0.1 0.1 1.0 -0.8 -0.8 -1.8 -1.8 -1.9
HDL Cholesterol 0.3 0.4 2.3 0.9 -1.1 -1.5 -0.5 -0.0 -0.1 -1.2 -0.7 -0.9 -1.3 -1.0 -1.0 0.0 -0.6 -0.4 -0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
LDL Cholesterol 9.2 14.5 49.3 6.2 -6.0 -3.8 -5.0 -5.2 -2.9 -5.8 -6.3 -6.0 -4.9 -6.1 -7.0 0.0 -2.6 3.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Lupus 0.2 0.3 1.9 -0.2 0.3 1.0 0.8 -0.6 0.2 0.6 0.1 0.1 -0.7 -0.1 1.1 0.1 0.6 -1.4 -0.0 -0.3 -0.4 -0.2 -0.3 -0.3 -0.1 -0.1 -0.3 -0.3 -0.5 -0.3
Neuroticism (2016) 0.5 0.8 3.3 -0.3 0.3 0.4 0.6 0.8 0.3 0.9 0.6 0.8 0.3 1.0 -0.1 0.9 0.9 -1.8 0.9 -1.0 -1.1 -0.9 -1.0 -1.0 -1.0 -0.9 -0.9 -1.1 -1.1 -0.8
Primary Biliary Cirrhosis 1.3 1.9 3.5 -1.3 1.8 0.5 1.2 0.3 1.4 1.4 1.1 1.5 1.2 1.6 1.1 1.4 1.7 -0.7 0.4 -1.7 -1.5 -1.3 -1.8 -1.7 -1.4 -1.3 -1.5 -1.4 -1.4 -1.9
Rheumatoid Arthritis 1.0 1.3 5.8 -1.7 1.3 1.2 1.7 1.3 2.2 1.4 1.4 1.6 1.1 1.6 2.4 0.0 1.7 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Schizophrenia (2014) 0.8 1.9 3.4 -1.4 1.1 0.0 1.4 0.9 1.0 1.8 1.5 1.5 1.8 1.5 1.0 1.4 1.1 0.8 1.0 -1.6 -1.5 -1.3 -1.8 -1.6 -1.4 -1.1 -1.3 -1.4 -1.4 -1.7
Triglycerides 1.4 2.2 8.6 2.2 -2.0 -0.7 -2.2 -2.8 -1.0 -2.6 -2.4 -1.9 -1.2 -2.1 -2.2 0.0 -1.1 2.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Type 2 Diabetes (T2D) (2012) 0.2 0.2 2.2 -0.2 0.1 0.0 0.3 -0.2 0.3 -0.6 0.3 0.4 0.8 0.2 0.9 0.0 0.6 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.5 0.8 3.5 -0.7 0.6 1.9 0.1 0.8 0.8 0.1 1.2 0.8 0.6 0.7 1.1 0.0 1.5 0.9 0.2 -0.9 -0.9 -0.7 -0.9 -0.9 -0.6 -0.7 -0.9 -0.8 -0.9 -1.1
Blood Eosinophil Count 0.2 1.5 9.1 0.9 -0.5 0.6 -0.1 -0.4 1.9 -1.4 -0.1 -0.3 0.1 -0.5 -0.2 -0.4 3.0 2.8 3.0 -0.1 -0.7 0.7 -0.9 -0.1 0.6 0.7 -0.2 -0.4 -1.6 -1.0
Blood Platelet Count 16.1 187.2 400.0 -12.4 11.7 7.6 16.6 5.9 16.6 10.3 11.7 12.6 11.6 12.7 7.1 12.8 20.0 1.3 11.6 -15.0 -17.9 -12.9 -17.1 -14.2 -12.9 -12.6 -15.4 -17.1 -19.2 -15.6
Blood Red Count 1.2 11.4 25.5 3.0 -3.8 -2.7 -3.5 -1.8 -4.4 -1.0 -3.4 -3.0 -3.2 -3.2 -1.9 -3.1 -5.0 0.9 -2.4 3.6 4.3 3.0 4.1 3.4 3.0 2.9 3.7 4.1 4.8 3.8
Blood White Count 0.1 0.9 4.2 1.2 -1.6 -0.8 -0.2 -1.9 0.2 0.2 -1.6 -0.9 -0.2 -0.8 0.4 -0.7 1.0 2.0 1.8 0.3 0.4 0.9 -0.1 0.3 0.7 1.0 0.8 0.6 0.0 -0.2
Heel T-Score 2.6 20.7 30.5 -5.5 4.7 2.1 4.0 3.8 2.0 5.5 4.5 5.3 5.3 5.4 4.5 5.3 2.4 -2.8 -1.5 -5.3 -4.5 -5.5 -4.8 -5.3 -5.4 -5.4 -5.2 -4.6 -3.3 -4.7
BMI 0.4 2.3 6.6 -1.6 1.6 0.9 1.9 1.4 1.4 1.4 1.9 1.4 0.9 1.3 2.6 1.6 1.1 -1.4 -0.3 -1.9 -1.1 -1.6 -1.7 -1.9 -1.6 -1.6 -1.5 -1.1 -0.5 -2.1
Height 1.3 24.9 50.3 5.5 -6.1 -5.1 -5.8 -7.1 -3.4 -2.6 -5.5 -5.8 -5.0 -5.0 -4.2 -5.5 -2.1 5.5 -0.9 5.4 4.5 5.6 4.9 5.5 5.6 5.5 5.1 4.6 3.1 4.8
Waist Hip Ratio (WHR) 0.6 2.5 7.4 -1.5 1.2 0.6 1.9 0.1 1.5 2.7 1.5 1.7 1.0 1.5 1.7 1.6 1.6 0.8 0.9 -1.9 -1.7 -1.6 -1.9 -1.9 -1.6 -1.6 -1.8 -1.6 -1.4 -2.0
Systolic Blood Pressure 0.8 4.1 10.6 -1.7 1.4 3.2 3.0 0.6 1.7 2.7 1.5 1.1 -0.1 1.1 1.1 1.5 3.2 -2.0 2.4 -2.0 -2.3 -1.5 -2.4 -2.0 -1.4 -1.6 -2.1 -2.1 -2.5 -2.5
Smoking Status 2.6 6.2 13.8 -2.4 2.4 1.5 2.8 1.7 3.7 1.8 2.4 2.3 2.4 2.2 2.9 2.2 3.0 -1.5 2.0 -2.8 -2.7 -2.3 -2.9 -2.8 -2.2 -2.4 -2.8 -2.5 -2.5 -3.2
Allergy or Eczema 0.2 0.4 3.8 0.2 0.0 -0.0 -1.1 -0.7 -2.0 -1.4 -0.9 -0.1 0.4 -0.1 -0.8 -0.4 0.2 0.4 -1.0 0.3 0.1 0.3 0.3 0.4 0.4 0.2 0.1 0.0 -0.1 0.3
Cardiovascular Disease 0.6 1.9 15.4 0.2 -0.5 -0.0 2.3 -0.4 2.0 1.4 0.1 -0.4 -1.4 -0.5 -0.5 -0.1 3.1 0.4 3.9 -0.6 -1.2 0.1 -1.3 -0.5 0.2 0.2 -0.6 -0.9 -1.9 -1.4
Hypothyroidism (self reported) 2.6 6.1 15.2 2.8 -2.9 -1.8 -2.0 -1.0 -1.4 -1.9 -2.2 -2.9 -3.9 -2.9 -2.2 -2.9 -1.6 1.2 0.1 2.8 2.6 2.9 2.6 2.7 2.9 2.9 2.8 2.8 2.1 2.4
Respiratory disease 0.5 1.1 6.7 0.3 -0.4 0.0 -1.6 -0.2 -2.6 -2.4 -0.8 0.2 0.2 0.2 0.4 -0.1 -1.6 0.8 -1.8 0.2 1.1 -0.0 0.5 -0.0 -0.0 0.1 0.5 1.0 1.8 0.2
Type 2 Diabetes (T2D) (2018) 0.4 0.7 5.3 -0.3 0.0 0.1 1.3 -0.8 1.1 -0.1 0.0 0.0 0.4 -0.2 0.8 -0.0 1.7 -0.0 2.3 -0.7 -0.7 -0.1 -0.8 -0.6 0.0 -0.3 -0.7 -0.6 -1.0 -1.3
Lung FEV1/FVC ratio 0.1 0.6 5.0 -0.2 0.8 0.6 1.2 0.4 1.6 2.2 0.3 0.0 0.2 -0.4 -0.3 0.1 0.6 -0.7 1.7 -0.0 -0.5 -0.0 -0.2 0.1 -0.0 -0.0 -0.3 -0.4 -0.8 0.0
Lung FVC 1.0 5.0 9.8 2.9 -3.0 -1.3 -2.0 -0.7 -0.7 -1.5 -2.4 -3.1 -1.3 -3.0 -0.3 -2.9 -0.7 1.9 0.8 2.3 2.5 3.0 2.0 2.2 3.0 3.0 2.6 2.8 1.9 1.4
Neuroticism 0.6 1.5 12.2 1.1 -1.2 0.3 -0.1 -1.6 0.7 -0.4 -1.4 -1.2 -1.6 -1.2 -1.6 -1.2 1.3 -0.1 3.5 0.9 -0.0 1.3 0.4 1.1 1.3 1.2 0.7 0.1 -1.0 0.6
Chronotype (morning person) 2.2 5.1 8.0 -2.8 2.5 1.9 2.4 1.9 0.7 2.3 1.6 2.7 2.2 2.6 2.3 2.6 1.3 -0.4 -1.3 -2.7 -2.3 -2.7 -2.4 -2.6 -2.6 -2.7 -2.7 -2.3 -1.7 -2.5
Hair Pigment 0.0 1.4 4.8 -1.6 0.8 1.0 0.3 0.9 -1.9 0.8 0.3 1.5 2.2 1.5 0.4 1.4 -0.9 -0.3 -2.0 -1.0 -0.7 -1.4 -0.7 -1.0 -1.4 -1.4 -1.0 -0.9 -0.1 -0.5
Tanning 0.1 0.7 11.8 -0.2 0.2 -0.3 0.1 0.8 0.2 0.8 0.6 -0.2 1.4 -0.2 -0.1 0.0 -1.2 -3.4 -0.8 0.2 0.3 -0.2 0.5 0.2 -0.1 -0.2 0.1 0.1 0.5 0.7
Hand grip strength (left) 0.6 1.5 5.1 1.1 -0.9 -1.0 -1.4 -0.7 -1.1 -0.4 -0.8 -1.1 -1.3 -0.9 -0.4 -1.0 -1.9 -0.3 -2.3 1.2 1.6 1.0 1.4 1.1 0.9 1.0 1.3 1.5 1.8 1.3
Number of treatments/medications taken 0.5 0.9 3.5 -0.4 -0.2 -0.6 1.5 -0.1 1.3 0.9 0.0 0.3 -0.2 0.3 1.7 0.3 1.5 -0.1 1.6 -1.1 -0.5 -0.4 -1.2 -1.2 -0.4 -0.5 -0.8 -0.3 -0.4 -1.9
Average weekly spirits intake 0.3 0.3 1.6 -0.4 0.5 -0.1 -0.5 1.2 -0.0 1.1 1.0 0.5 0.5 0.5 0.3 0.3 -1.0 0.2 -1.3 -0.2 0.2 -0.4 0.1 -0.2 -0.4 -0.4 -0.2 0.1 0.6 0.1
Sensitivity / hurt feelings 0.1 0.2 2.9 -0.1 0.4 1.7 -0.1 0.0 -0.2 -0.3 -0.3 -0.0 0.6 -0.0 -0.5 -0.1 -0.2 0.1 0.1 0.2 0.1 0.2 0.2 0.3 0.1 0.1 0.2 -0.0 -0.0 0.3
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.6 0.4 -0.3 0.6 -0.5 0.1 -0.7 -0.9 -0.7 -0.4 -1.3 -0.6 -1.1 -0.5 -0.5 0.1 0.2 0.7 0.3 0.5 0.6 0.7 0.5 0.6 0.6 0.3 0.1 0.8
Hearing difficulty/problems: Yes 4.2 6.5 11.2 -3.0 2.7 1.3 2.7 2.0 1.1 3.4 2.4 3.1 2.8 2.9 2.0 2.9 1.6 -0.9 0.1 -2.9 -2.8 -3.0 -2.7 -2.8 -3.0 -3.0 -2.9 -2.9 -2.3 -2.5
Relative age of first facial hair 0.1 0.2 2.7 -0.0 0.9 -0.1 0.3 0.3 1.6 0.4 0.1 -0.0 -0.4 -0.2 0.1 -0.3 0.4 0.0 -0.8 0.1 -0.1 0.1 0.1 0.2 0.2 0.0 -0.2 -0.1 -0.3 0.1
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 2.7 0.7 -0.3 -0.5 -0.3 -0.3 -1.6 -0.3 -1.3 -0.6 -1.1 -0.7 0.4 -0.7 -1.0 -0.2 -0.4 0.7 1.1 0.7 0.7 0.5 0.7 0.7 0.8 1.1 1.2 0.5
Ever used hormone-replacement therapy (HRT) 0.8 1.0 3.0 1.0 -1.7 -1.7 -0.5 -0.9 0.4 -1.0 -0.8 -1.0 -0.4 -1.1 -1.4 -1.0 -0.0 0.9 1.7 1.0 0.5 1.1 0.7 1.0 1.0 1.1 0.8 0.6 0.1 0.9
Ever had hysterectomy (womb removed) 0.2 0.3 3.3 -0.0 -0.1 1.8 0.4 0.4 0.9 -0.6 0.1 -0.0 -0.4 0.0 1.0 0.1 0.5 -0.3 0.2 -0.3 0.1 -0.0 -0.4 -0.4 -0.0 0.1 -0.1 0.2 0.2 -0.7
Systolic blood pressure, automated reading 0.1 0.4 1.8 -0.1 0.1 1.4 1.2 -0.1 0.3 0.2 0.1 -0.3 -1.1 -0.2 0.7 0.1 1.1 -1.2 1.2 -0.4 -0.2 -0.1 -0.6 -0.5 -0.0 -0.1 -0.3 -0.1 -0.3 -0.9
Eye problems/disorders: Diabetes related eye disease 0.9 1.0 2.0 -1.2 1.1 0.3 1.4 0.8 1.0 -0.2 0.5 1.0 0.1 0.7 0.9 0.9 1.0 -1.1 0.4 -1.2 -1.1 -1.0 -1.1 -1.2 -0.9 -1.1 -1.3 -1.0 -1.0 -1.4
Angina 2.1 2.7 9.0 -1.9 1.7 1.1 1.4 0.9 0.5 3.0 1.7 2.0 1.1 2.0 1.5 2.0 0.7 -0.8 -0.7 -1.8 -1.6 -2.0 -1.6 -1.8 -2.0 -2.0 -1.9 -1.6 -1.1 -1.5
Medication for hormone replacement therapy 0.5 0.6 3.9 0.5 -1.2 -1.5 -0.2 -0.3 -0.3 -0.7 -0.7 -0.4 0.3 -0.3 -1.1 -0.4 0.6 2.0 1.9 0.3 -0.2 0.4 0.0 0.4 0.4 0.5 0.2 -0.1 -0.7 0.2
Vitamin and mineral supplements 0.5 0.6 3.5 -0.5 0.9 0.2 0.4 1.9 1.3 0.6 1.1 0.8 0.8 0.5 1.1 0.6 0.3 -1.6 -0.5 -0.7 -0.4 -0.6 -0.6 -0.7 -0.6 -0.6 -0.5 -0.4 -0.2 -0.8
Supplements: Zinc 0.6 0.6 5.4 0.5 0.1 0.6 -0.0 -0.1 2.0 -0.4 0.7 -0.4 -0.4 -0.4 0.3 -0.5 1.0 -1.7 2.3 0.0 -0.2 0.4 -0.2 0.1 0.5 0.4 0.0 0.0 -0.5 -0.4
Medication: Co-codamol 2.3 2.6 4.5 -1.8 1.3 1.1 1.4 2.1 0.5 1.0 2.0 2.0 2.0 2.0 0.6 2.0 0.9 -0.3 -0.2 -1.8 -1.8 -2.0 -1.7 -1.8 -2.0 -1.9 -1.8 -1.8 -1.5 -1.5
Medication: Metformin 0.5 0.8 5.1 -0.4 0.2 -0.5 1.4 0.1 1.2 0.8 0.4 0.5 0.1 0.3 -0.2 0.5 1.4 0.5 2.3 -0.7 -1.1 -0.5 -0.8 -0.6 -0.4 -0.6 -0.8 -1.0 -1.3 -0.9
Diabetes (father) 1.2 1.4 4.5 1.2 -0.8 -0.2 -1.0 -1.6 -2.1 -1.7 -1.7 -1.2 -1.2 -1.2 -1.1 -1.1 -1.1 -0.4 -0.2 1.2 1.2 1.1 1.2 1.2 1.1 1.2 1.3 1.2 1.1 1.2
Diabetes (mother) 1.0 1.3 2.3 -1.2 1.2 0.7 1.3 0.8 0.7 0.9 1.1 1.4 1.2 1.3 0.4 1.4 1.1 -0.5 0.5 -1.2 -1.5 -1.3 -1.4 -1.2 -1.4 -1.1 -1.3 -1.5 -1.5 -1.0
Severe depression (siblings) 1.8 2.1 3.7 1.7 -1.7 -1.3 -1.4 -1.9 -0.1 -1.1 -1.7 -1.8 -1.2 -1.6 -1.4 -1.8 -0.1 0.1 1.0 1.6 1.2 1.8 1.3 1.6 1.8 1.8 1.6 1.3 0.6 1.4
Pack years adult smoking proportion 2.3 3.4 6.1 -1.7 1.4 1.2 2.1 1.2 1.7 1.4 1.3 1.9 1.9 1.8 1.1 1.9 2.5 -0.6 1.6 -2.2 -2.3 -1.9 -2.4 -2.1 -1.9 -1.8 -2.1 -2.1 -2.2 -2.3
Impedance of leg (right) 4.0 19.5 28.9 5.2 -5.0 -3.0 -4.2 -4.1 -1.2 -4.0 -4.6 -5.0 -4.0 -5.2 -5.1 -5.2 -2.4 3.5 2.5 5.2 4.0 5.2 4.8 5.4 5.2 5.2 4.8 4.1 2.6 4.9
Leg fat-free mass (left) 0.1 0.7 3.6 -0.7 0.5 0.2 0.8 0.1 -0.3 0.7 0.6 0.5 0.3 0.8 1.6 0.7 0.9 0.5 -1.9 -1.1 -0.5 -0.7 -1.0 -1.1 -0.7 -0.8 -0.8 -0.5 -0.3 -1.4
Trunk fat percentage 0.2 0.7 3.5 1.0 -1.0 -0.2 -0.5 -1.9 0.4 -1.0 -0.9 -1.0 -1.0 -1.0 -0.0 -0.8 0.4 1.2 0.3 0.6 0.7 0.9 0.3 0.5 0.9 0.9 0.7 0.8 0.4 0.1
Hand grip strength (right) 0.3 0.7 3.6 0.7 -0.6 -1.4 -0.9 -0.4 -0.9 -0.6 -0.8 -0.7 -1.0 -0.5 -0.2 -0.6 -1.1 -0.1 -1.9 0.7 1.0 0.6 0.8 0.6 0.5 0.6 0.8 1.0 1.1 0.8
Townsend deprivation index at recruitment 0.6 0.9 2.1 -1.2 0.8 1.1 1.4 1.2 0.3 0.7 0.8 1.0 0.9 0.9 0.2 1.0 0.5 -0.2 -0.0 -1.0 -1.0 -1.1 -0.8 -0.9 -1.0 -1.2 -1.3 -1.1 -0.8 -0.9
Current tobacco smoking 0.4 0.6 6.1 -0.0 -0.0 -0.0 0.9 0.0 1.2 0.8 -0.1 0.2 0.4 -0.0 -0.1 0.2 1.5 -0.4 2.5 -0.4 -0.8 -0.1 -0.7 -0.3 -0.1 -0.1 -0.5 -0.7 -1.2 -0.6
Average weekly fortified wine intake 3.2 3.7 5.8 2.0 -1.7 -1.8 -2.0 -1.4 -1.7 -1.6 -2.2 -2.1 -2.4 -2.1 -1.3 -2.1 -1.9 0.9 -0.9 2.1 2.2 2.1 2.2 2.1 2.1 2.0 2.1 2.1 2.0 2.0
Maternal smoking around birth 0.5 0.7 3.3 -0.3 0.3 1.1 0.8 -0.8 0.4 -0.3 -0.6 0.7 1.1 0.4 -0.6 0.3 1.6 1.8 1.6 -0.4 -1.0 -0.2 -0.8 -0.3 -0.3 -0.2 -0.5 -0.9 -1.5 -0.5
Fed-up feelings 0.7 1.4 5.0 1.1 -0.5 0.5 -0.4 -0.0 0.7 -2.2 -1.3 -1.5 -1.2 -1.7 -1.4 -1.6 0.3 -0.4 1.9 1.2 0.6 1.5 1.0 1.4 1.6 1.2 0.9 0.6 -0.2 0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.6 4.1 0.6 -0.4 0.1 -0.3 -0.9 -0.4 -0.6 -1.2 -0.6 -0.5 -0.9 -2.0 -0.8 -0.2 0.4 1.0 0.9 0.1 0.7 0.8 1.1 0.7 0.7 0.5 0.1 -0.5 1.2
Relative age voice broke 0.1 0.2 1.7 0.1 0.4 0.5 0.3 1.2 1.0 0.0 0.0 -0.1 0.1 -0.2 1.3 -0.2 0.4 -0.1 -0.3 -0.1 0.3 0.2 -0.2 -0.2 0.2 0.2 0.1 0.4 0.3 -0.5
Taking other prescription medications 0.7 1.1 3.8 1.4 -1.2 -0.7 -0.7 -0.2 -0.3 -1.9 -1.3 -1.3 -0.2 -1.3 -0.1 -1.4 0.2 -0.4 0.9 0.9 1.1 1.3 0.7 0.8 1.3 1.4 1.1 1.3 0.9 0.4
Age when periods started (menarche) 0.2 0.6 2.2 0.7 -0.4 -0.9 -0.2 -1.4 0.9 0.8 -0.3 -1.0 -1.5 -0.8 0.0 -0.9 0.5 -0.1 1.3 0.5 0.4 0.9 0.4 0.5 0.9 0.8 0.5 0.5 -0.0 0.1
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 3.3 1.3 -1.7 -1.7 -1.3 0.7 -0.5 -0.9 -0.6 -1.3 -1.3 -1.3 0.1 -1.2 -0.9 -0.1 -0.3 1.2 1.7 1.4 1.1 1.0 1.3 1.5 1.5 1.8 1.8 0.9
Heel bone mineral density (BMD) T-score, automated (left) 2.4 5.4 9.1 -2.9 2.7 2.1 1.0 1.6 -0.0 2.9 2.2 2.8 2.6 3.0 2.5 2.8 0.2 -1.0 -2.3 -2.7 -1.9 -2.9 -2.2 -2.8 -2.9 -2.9 -2.5 -2.1 -0.9 -2.3
Tinnitus: Yes, but not now, but have in the past 12.6 13.5 21.3 4.6 -3.7 -3.2 -3.8 -3.5 -1.2 -3.1 -3.8 -4.5 -2.4 -4.4 -3.0 -4.5 -2.3 0.1 0.2 4.2 4.0 4.5 4.1 4.2 4.5 4.3 4.3 4.0 3.1 3.8
Qualifications: CSEs or equivalent 0.2 0.3 1.9 -0.1 0.2 0.5 0.7 0.8 0.6 -0.1 0.0 0.1 0.3 0.1 0.3 0.3 1.4 -0.8 0.7 -0.5 -0.6 -0.1 -0.8 -0.5 -0.2 -0.1 -0.4 -0.5 -0.9 -0.8
Serious illness, injury or assault to yourself 0.1 0.1 1.6 0.1 0.5 -0.2 -0.1 0.2 -0.8 -0.2 -0.5 -0.3 -0.1 -0.3 0.0 -0.1 -0.4 -1.3 -0.1 0.2 0.3 0.1 0.3 0.2 0.2 0.1 0.1 0.3 0.5 0.1
High blood pressure 1.9 5.2 12.6 -1.7 1.0 1.0 3.3 1.3 3.3 3.2 1.9 1.6 0.4 1.5 1.4 1.8 3.5 -0.7 2.9 -2.5 -2.6 -1.8 -2.9 -2.5 -1.8 -1.8 -2.5 -2.3 -2.7 -3.1
Hayfever, allergic rhinitis or eczema 0.5 1.0 5.5 0.8 -0.7 0.5 -1.8 -1.0 -2.4 -2.3 -1.4 -0.4 -0.1 -0.5 -1.3 -0.7 -0.4 0.9 -1.1 0.8 0.6 0.7 0.8 0.8 0.7 0.6 0.6 0.5 0.4 0.8
Multivitamins +/- minerals 0.4 0.5 2.6 0.5 -0.7 -0.1 -0.2 -1.6 -0.9 -0.5 -1.0 -0.8 -1.1 -0.6 -1.1 -0.6 0.2 1.2 0.9 0.6 0.1 0.6 0.5 0.7 0.7 0.6 0.4 0.2 -0.3 0.6
Stomach or abdominal pain in last month 0.3 0.4 6.4 -0.0 -0.0 -0.4 0.7 0.9 0.4 0.8 0.3 0.0 0.1 -0.0 0.6 0.0 -0.6 -2.5 -0.1 -0.1 0.4 0.0 0.0 -0.1 -0.1 -0.0 0.2 0.3 0.7 -0.1
Supplements: Glucosamine 0.6 0.7 2.6 -0.8 0.4 -1.1 0.6 0.2 0.3 0.8 0.6 0.9 0.9 0.7 1.6 0.9 0.6 0.3 0.1 -1.2 -0.7 -0.9 -1.0 -1.2 -0.9 -1.0 -1.0 -0.7 -0.4 -1.4
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 0.8 0.5 -0.7 0.0 -0.8 0.8 0.3 -0.9 -0.1 -0.5 -0.7 -0.5 -0.3 -0.4 -0.8 -0.7 -0.4 0.5 0.7 0.4 0.5 0.4 0.4 0.5 0.6 0.7 0.8 0.5
Medication: Atenolol 1.0 1.2 4.1 -1.1 0.9 0.4 1.5 0.4 2.0 1.8 1.7 1.0 0.1 0.8 1.2 0.9 0.4 -1.8 0.5 -1.1 -0.7 -1.0 -1.0 -1.2 -1.0 -1.1 -1.0 -0.8 -0.4 -1.2
Medication: Levothyroxine sodium 1.1 1.9 3.9 1.4 -1.1 -0.0 -1.5 0.0 -1.7 -0.4 -0.9 -1.2 -2.0 -1.2 -1.8 -1.4 -1.3 1.2 -1.0 1.7 1.4 1.4 1.6 1.7 1.3 1.5 1.7 1.3 1.1 1.9
Sitting height 0.4 2.6 11.6 1.8 -2.6 -1.9 -0.8 -2.6 -0.6 -1.3 -1.6 -1.9 -2.2 -1.6 -1.4 -1.7 0.7 3.4 0.6 1.2 1.0 1.7 1.0 1.3 1.7 1.6 1.2 1.1 0.4 0.7
Chronic bronchitis/emphysema (father) 0.4 0.5 1.1 0.6 -0.7 0.1 -0.8 0.0 0.0 -0.9 -0.5 -0.7 -1.0 -0.6 -0.8 -0.6 -1.0 0.1 0.2 0.9 0.7 0.7 0.9 0.9 0.7 0.7 0.8 0.6 0.5 1.0
High blood pressure (mother) 1.0 1.4 4.1 -1.2 0.9 2.0 1.2 0.3 1.4 1.1 1.2 1.2 0.6 1.1 0.5 1.1 1.2 1.2 1.2 -1.3 -1.4 -1.2 -1.3 -1.2 -1.1 -1.2 -1.3 -1.3 -1.3 -1.3
Body mass index (BMI) 0.5 2.2 3.8 -1.6 1.6 1.1 1.9 1.0 0.9 1.2 1.6 1.6 1.3 1.5 1.8 1.7 1.4 -0.9 -0.5 -1.9 -1.4 -1.7 -1.9 -1.9 -1.7 -1.6 -1.6 -1.4 -1.0 -2.0
Impedance of leg (left) 3.4 16.4 24.7 4.8 -4.5 -2.5 -4.0 -3.9 -1.0 -3.9 -4.2 -4.6 -3.9 -4.7 -4.8 -4.7 -2.1 2.7 2.4 4.8 3.6 4.8 4.3 5.0 4.7 4.7 4.4 3.6 2.1 4.6
Leg predicted mass (left) 0.1 0.7 3.5 -0.7 0.5 0.1 0.7 0.1 -0.3 0.7 0.6 0.5 0.3 0.7 1.5 0.7 0.9 0.5 -1.9 -1.0 -0.5 -0.7 -1.0 -1.1 -0.7 -0.7 -0.8 -0.4 -0.3 -1.4
Trunk fat mass 0.2 1.0 4.4 1.3 -1.3 -0.7 -0.8 -2.1 0.0 -1.0 -1.0 -1.3 -1.4 -1.2 -0.1 -1.1 0.3 1.3 -0.0 0.8 0.9 1.2 0.5 0.7 1.1 1.1 0.9 1.0 0.7 0.2
Waist circumference 0.3 1.1 3.1 -0.9 0.7 0.4 1.4 -0.4 1.1 0.7 0.6 0.8 0.8 0.8 1.6 1.0 1.6 -0.2 0.4 -1.4 -1.0 -1.0 -1.5 -1.4 -1.0 -1.0 -1.2 -0.9 -0.9 -1.8
Number of incorrect matches in round 4.0 6.6 11.8 3.1 -2.9 -3.1 -2.5 -2.8 -1.7 -1.6 -3.4 -3.1 -2.3 -2.9 -0.7 -2.9 -1.7 0.6 0.8 2.7 2.9 3.0 2.6 2.6 2.9 3.0 2.9 3.0 2.5 2.2
Past tobacco smoking 1.7 3.1 4.9 2.2 -2.0 -0.7 -1.7 -0.8 -1.7 -2.2 -2.1 -2.2 -0.9 -2.0 -1.8 -1.8 -1.1 0.3 0.1 2.0 1.7 2.0 1.7 2.0 1.9 2.2 2.1 1.8 1.2 1.9
Alcohol usually taken with meals 1.2 2.0 3.6 -1.9 1.9 1.6 1.0 0.7 0.7 1.0 1.7 1.5 1.4 1.6 1.4 1.5 0.8 0.9 -0.0 -1.6 -1.4 -1.7 -1.4 -1.6 -1.6 -1.7 -1.6 -1.5 -1.1 -1.4
Nervous feelings 0.1 0.2 1.2 0.4 -0.4 0.6 -0.3 -0.1 0.6 0.5 0.3 -0.4 -0.4 -0.3 -0.9 -0.3 -0.0 -0.4 1.1 0.4 0.1 0.4 0.3 0.5 0.3 0.4 0.4 0.1 -0.1 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 1.9 -0.2 0.5 0.6 -0.5 0.3 -1.4 0.2 -0.2 0.3 0.3 0.2 0.1 0.1 -0.7 -1.0 -0.8 0.0 0.2 -0.2 0.2 0.0 -0.2 -0.2 0.1 0.1 0.4 0.3
Hearing difficulty/problems with background noise 2.6 4.1 7.5 -2.1 1.7 1.6 2.1 0.4 1.0 2.7 1.2 2.3 1.8 2.2 0.8 2.2 2.2 -0.1 1.6 -2.2 -2.7 -2.2 -2.4 -2.1 -2.2 -2.1 -2.4 -2.7 -2.7 -2.0
Hair/balding pattern: Pattern 2 6.6 8.4 13.9 2.9 -2.8 -1.9 -3.7 -1.8 -2.5 -3.6 -1.8 -2.6 -2.5 -2.7 -1.3 -3.0 -3.5 2.1 -1.4 3.2 3.7 2.9 3.4 3.1 2.9 2.9 3.4 3.6 3.7 3.2
Had menopause 3.0 3.7 8.5 2.1 -2.3 -1.9 -1.4 -1.3 -0.3 -2.9 -2.2 -2.4 -2.0 -2.5 -1.3 -2.4 -0.4 -0.5 2.0 2.1 1.8 2.3 1.8 2.1 2.4 2.2 1.9 1.9 1.1 1.5
Had other major operations 0.2 0.2 1.0 0.5 -0.0 -0.1 -0.2 0.4 0.7 -0.8 0.2 -0.4 -0.1 -0.5 -0.1 -0.5 -0.2 1.0 -0.0 0.3 0.4 0.5 0.3 0.3 0.5 0.5 0.4 0.5 0.4 0.1
Forced vital capacity (FVC) 2.8 10.9 18.3 4.0 -4.3 -2.4 -3.5 -2.4 -2.5 -2.1 -3.5 -4.2 -3.1 -3.9 -1.2 -4.0 -2.0 1.9 -0.6 3.6 3.8 4.0 3.3 3.4 4.0 4.0 3.8 4.0 3.2 2.8
Heel bone mineral density (BMD) T-score, automated (right) 3.4 7.7 12.5 -3.4 2.9 2.7 1.7 2.1 1.0 3.2 2.8 3.1 3.5 3.4 3.2 3.1 1.2 -1.3 -1.7 -3.3 -2.5 -3.3 -2.8 -3.3 -3.2 -3.3 -3.0 -2.5 -1.5 -3.0
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 2.2 1.2 -1.3 -1.4 -0.8 -0.5 -1.0 -1.0 -1.1 -1.1 -1.0 -1.2 -0.5 -1.1 -1.1 0.1 -0.8 1.1 1.4 1.1 1.2 1.1 1.1 1.1 1.2 1.4 1.5 1.0
Qualifications: None of the above 1.2 2.5 4.5 -1.7 1.5 1.4 1.7 1.2 2.1 1.9 1.9 1.6 1.6 1.4 1.6 1.5 1.1 -1.5 1.2 -1.7 -1.5 -1.6 -1.7 -1.7 -1.5 -1.6 -1.7 -1.5 -1.3 -1.7
Financial difficulties in last 2 years 0.2 0.3 1.4 -0.2 0.4 0.7 0.2 1.2 0.4 -0.4 0.8 0.2 0.3 0.3 0.4 0.2 0.8 -0.6 0.8 -0.5 -0.4 -0.2 -0.7 -0.5 -0.2 -0.3 -0.5 -0.4 -0.5 -0.9
Mouth/teeth dental problems 0.2 0.4 1.9 -0.5 0.6 0.5 -0.1 -0.2 -1.4 -0.1 -0.5 0.6 1.0 0.5 -0.5 0.6 0.6 1.0 0.5 -0.4 -0.7 -0.6 -0.3 -0.3 -0.5 -0.4 -0.5 -0.7 -0.8 -0.0
Heart attack 0.3 0.4 1.5 -0.6 0.4 0.7 1.2 -0.2 -0.3 0.4 0.4 0.8 -0.5 0.5 -0.3 0.8 0.5 -0.0 0.5 -0.7 -0.9 -0.8 -0.7 -0.6 -0.8 -0.7 -0.7 -0.9 -0.8 -0.4
Allergy 0.5 1.3 9.5 -0.8 0.7 -0.6 2.1 1.2 2.3 3.1 1.4 0.5 -0.2 0.5 0.4 0.8 0.6 -0.8 1.1 -0.6 -0.9 -0.7 -0.7 -0.6 -0.8 -0.6 -0.7 -0.9 -1.1 -0.4
Pain all over the body in last month 0.3 0.4 1.4 -0.2 0.4 0.5 0.5 0.6 0.3 -0.1 0.5 0.4 0.2 0.4 0.9 0.4 1.2 -0.5 0.6 -0.7 -0.7 -0.4 -0.9 -0.7 -0.4 -0.4 -0.5 -0.7 -0.8 -0.9
Diabetes (self-reported) 0.3 0.4 3.4 0.0 -0.3 -0.9 1.2 -1.0 -0.2 -0.1 -0.6 -0.2 -0.3 -0.4 0.9 -0.2 1.2 0.1 1.9 -0.4 -0.2 0.2 -0.5 -0.4 0.3 0.0 -0.3 -0.1 -0.4 -1.0
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 3.7 1.0 -0.6 0.4 -0.7 -0.9 -1.1 -1.9 -1.9 -1.0 -1.6 -1.2 -1.5 -1.1 0.1 0.5 0.0 1.1 0.5 1.1 1.0 1.2 1.2 1.0 0.8 0.5 -0.0 1.0
Medication: Ramipril 0.1 0.2 1.0 -0.3 0.0 0.3 1.0 -0.1 -0.0 0.2 -0.2 0.1 -0.8 0.0 -0.9 0.2 0.2 -0.7 0.5 -0.2 -0.3 -0.3 -0.0 -0.1 -0.2 -0.3 -0.3 -0.3 -0.3 0.0
Medication: Simvastatin 1.2 1.8 9.7 1.6 -1.8 -3.1 -0.5 -1.0 0.7 -0.8 -0.7 -1.6 -1.3 -1.7 -0.1 -1.6 -0.3 0.3 1.6 1.1 1.3 1.5 0.9 1.0 1.5 1.5 1.3 1.5 1.1 0.5
Fluid intelligence score 0.9 2.0 6.2 1.2 -1.6 -1.7 -2.0 -1.1 -2.4 -1.2 -1.1 -1.1 -1.4 -0.9 -1.7 -1.0 -1.4 2.5 -0.4 1.3 1.3 1.1 1.4 1.3 1.0 1.1 1.3 1.2 1.2 1.5
Illnesses of siblings 0.4 0.5 3.2 0.5 -0.6 -1.1 -1.0 -1.0 -0.7 -1.1 -0.8 -0.5 -0.1 -0.4 -0.6 -0.4 -0.1 1.8 -0.3 0.6 0.4 0.5 0.5 0.6 0.6 0.6 0.6 0.5 0.2 0.7
Neuroticism score 0.7 1.5 4.8 1.2 -1.1 0.7 -0.7 -1.6 -0.0 -0.6 -1.7 -1.3 -1.7 -1.5 -1.8 -1.5 0.3 -0.1 2.2 1.2 0.5 1.5 1.0 1.4 1.5 1.3 1.0 0.5 -0.3 1.0
Weight 0.0 0.2 1.6 0.5 -0.5 -0.6 0.0 -1.2 0.1 -0.3 -0.3 -0.6 -0.6 -0.4 0.5 -0.3 0.8 0.8 -0.6 -0.0 0.2 0.4 -0.2 -0.1 0.4 0.3 0.1 0.3 0.1 -0.5
Impedance of arm (right) 0.7 3.4 6.4 2.1 -2.0 -0.5 -2.0 -2.5 0.1 -2.0 -2.4 -2.1 -1.6 -2.0 -2.2 -2.1 0.0 1.5 1.9 2.1 1.2 2.2 1.7 2.2 2.2 2.2 1.8 1.3 0.2 2.0
Arm fat percentage (right) 0.2 0.6 1.2 -0.7 0.7 0.9 0.9 -0.1 0.8 0.3 0.7 0.8 0.6 0.7 1.0 0.9 0.8 -0.1 -0.3 -1.0 -0.7 -0.9 -1.0 -1.1 -0.9 -0.8 -0.8 -0.6 -0.4 -1.1
Trunk fat-free mass 0.1 0.6 3.2 0.7 -0.9 -1.6 -0.6 -0.8 -1.0 -0.1 -0.2 -0.8 -0.7 -0.5 0.1 -0.7 -0.2 1.4 -1.8 0.4 0.7 0.6 0.4 0.3 0.6 0.5 0.5 0.8 0.8 0.1
Hip circumference 0.1 0.3 1.5 0.6 -0.5 -0.7 -0.2 -1.2 -0.4 -1.2 -0.9 -0.7 -0.1 -0.6 0.8 -0.5 0.4 0.4 -0.3 0.2 0.5 0.5 0.0 0.0 0.5 0.5 0.4 0.7 0.6 -0.3
Time employed in main current job 0.1 0.1 0.5 -0.3 0.3 0.2 0.2 0.2 0.7 -0.3 0.1 0.2 0.3 0.3 -0.0 0.3 0.2 0.0 0.3 -0.2 -0.2 -0.3 -0.2 -0.2 -0.3 -0.2 -0.2 -0.2 -0.2 -0.1
Alcohol intake versus 10 years previously 0.1 0.1 0.7 0.6 -0.8 -0.2 -0.2 0.6 0.1 -0.2 0.2 -0.5 -0.6 -0.5 0.2 -0.4 0.4 -0.3 0.4 0.1 0.2 0.4 0.0 0.1 0.4 0.4 0.3 0.4 0.2 -0.2
Father’s age at death 0.2 0.3 1.1 -0.7 0.7 0.4 -0.5 -0.2 -0.8 0.8 0.4 0.3 0.4 0.5 0.5 0.4 -0.8 -0.2 -1.1 -0.2 -0.1 -0.5 0.0 -0.2 -0.5 -0.6 -0.3 -0.2 0.3 0.0
Worrier / anxious feelings 0.1 0.1 0.7 -0.3 0.2 0.7 -0.1 0.2 0.7 0.8 0.0 0.2 0.5 0.1 0.3 0.2 0.2 -0.1 0.7 -0.3 -0.2 -0.2 -0.2 -0.3 -0.2 -0.4 -0.3 -0.3 -0.2 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 3.7 0.7 -0.4 -1.2 0.1 0.1 1.0 -1.1 0.2 -0.6 -0.3 -0.6 -1.2 -0.5 0.8 -1.6 1.9 0.5 -0.1 0.6 0.1 0.5 0.6 0.7 0.4 0.0 -0.6 0.3
Falls in the last year 0.4 0.6 1.6 0.5 -0.2 -0.0 -0.7 -1.0 -0.9 -0.5 -0.7 -0.6 -0.7 -0.7 -1.2 -0.6 -0.8 0.9 -0.1 0.9 0.5 0.6 1.0 1.0 0.6 0.6 0.7 0.4 0.3 1.2
Hair/balding pattern: Pattern 3 0.5 0.8 4.3 -0.2 -0.1 -0.5 0.8 1.1 0.9 2.1 0.6 0.1 -1.0 0.3 -0.2 0.5 2.0 -0.9 0.8 -0.7 -0.9 -0.3 -1.1 -0.7 -0.3 -0.2 -0.7 -0.7 -1.2 -1.1
Number of live births 0.2 0.3 2.7 -0.3 0.4 0.0 -0.3 1.6 -0.0 -0.5 0.6 0.4 1.6 0.4 0.6 0.3 0.2 -0.8 -0.5 -0.3 -0.2 -0.3 -0.4 -0.4 -0.3 -0.3 -0.3 -0.2 -0.2 -0.4
Forced expiratory volume in 1-second (FEV1) 3.0 10.1 16.3 3.8 -3.9 -2.0 -3.2 -2.0 -2.1 -1.9 -3.2 -4.0 -2.9 -3.9 -1.1 -3.9 -2.2 2.0 -0.5 3.5 3.8 3.9 3.3 3.4 3.9 3.9 3.7 3.9 3.2 2.8
Pulse rate 2.4 4.1 8.0 -1.9 1.6 0.2 2.6 1.2 0.9 1.4 1.6 2.1 2.0 2.0 1.1 2.2 2.8 -0.9 1.7 -2.3 -2.6 -2.1 -2.6 -2.2 -2.1 -2.0 -2.4 -2.5 -2.7 -2.3
Happiness 0.3 0.4 4.2 -0.1 0.5 2.0 0.6 -0.4 -1.0 0.2 -0.9 0.1 -0.0 -0.1 0.7 0.1 0.4 -1.2 -0.4 -0.2 -0.1 -0.1 -0.3 -0.3 -0.0 -0.1 -0.2 -0.0 -0.0 -0.5
Noisy workplace 0.7 0.9 4.5 1.0 -1.1 -0.4 0.6 -0.9 1.0 -0.6 -1.3 -1.3 -0.4 -1.2 0.1 -1.1 2.0 -0.9 2.1 0.4 0.0 1.1 -0.1 0.4 1.1 1.1 0.4 0.3 -0.7 -0.4
Qualifications: A levels/AS levels or equivalent 0.5 1.1 4.9 0.4 -0.4 -0.8 -1.0 0.1 -1.7 0.9 -0.1 -0.5 -1.2 -0.2 0.4 -0.4 -1.9 1.0 -2.2 0.7 1.4 0.3 1.1 0.5 0.3 0.4 0.9 1.3 2.0 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 2.0 1.3 -1.4 -0.9 -0.9 -1.4 -1.0 -1.4 -1.0 -1.0 -1.3 -0.9 -0.6 -1.1 0.1 0.1 -0.1 0.9 0.8 1.1 0.6 0.8 1.1 1.2 1.0 0.9 0.6 0.5
Mouth/teeth dental problems: Dentures 3.4 5.8 10.4 -2.8 1.7 0.4 2.8 2.0 1.6 2.4 2.5 2.7 1.4 2.6 3.0 2.6 1.8 -1.3 -0.5 -3.0 -2.4 -2.7 -3.0 -3.1 -2.7 -2.7 -2.8 -2.4 -1.7 -3.2
Asthma 0.9 1.7 8.9 1.3 -1.3 -0.2 -2.0 -0.4 -2.1 -3.0 -1.2 -0.8 -0.2 -0.7 -0.9 -1.0 -1.5 0.7 -1.0 1.1 1.4 0.9 1.2 1.0 0.9 1.0 1.3 1.4 1.7 1.2
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.1 0.8 -0.0 0.2 0.4 0.3 0.5 0.6 -0.1 -0.1 -0.0 -0.0 0.1 0.2 0.0 -0.2 0.0 -0.9 -0.0 0.1 -0.1 0.1 -0.0 -0.1 -0.1 0.0 -0.1 0.2 0.0
Medication: Cholesterol lowering 0.9 1.4 4.7 1.2 -1.3 -2.2 -1.1 -0.3 -0.6 -0.6 -0.9 -1.2 -1.8 -1.4 0.4 -1.3 -1.0 -0.8 -0.3 0.9 1.6 1.2 1.0 0.7 1.2 1.2 1.2 1.8 1.8 0.5
Depression (self-reported) 0.8 0.9 9.1 0.5 0.3 0.3 0.5 -0.4 3.0 -1.2 -0.1 -0.2 -0.4 -0.5 -0.4 -0.4 2.1 0.1 2.2 -0.1 -0.7 0.4 -0.6 0.0 0.4 0.5 -0.1 -0.4 -1.4 -0.4
Medication: Lansoprazole 0.2 0.2 1.1 0.2 -0.3 -0.2 -0.5 -0.4 -0.6 -0.2 -1.1 -0.2 -0.2 -0.4 -0.3 -0.3 -0.6 -0.8 -0.5 0.3 0.5 0.3 0.6 0.3 0.4 0.2 0.2 0.4 0.5 0.3
Prospective memory result 0.9 1.1 2.0 -1.1 0.9 1.3 1.4 1.2 1.0 1.1 1.1 0.8 1.1 0.9 1.2 1.0 0.5 -1.4 0.4 -1.1 -0.8 -0.9 -1.0 -1.1 -0.9 -1.0 -1.0 -0.8 -0.5 -1.3
Lung cancer (father) 0.9 1.0 3.5 -1.0 0.6 1.3 1.3 1.1 -1.1 0.6 0.4 0.9 1.9 0.8 1.1 1.1 0.5 -1.7 -0.6 -1.1 -0.6 -1.1 -0.9 -1.2 -1.1 -1.0 -0.9 -0.5 -0.1 -1.0
Illnesses of mother 1.6 1.9 5.0 1.1 -0.7 -1.1 -1.7 -0.7 -1.3 -0.1 -1.1 -1.4 -1.4 -1.2 -0.8 -1.2 -2.2 -0.6 -2.0 1.6 1.7 1.2 1.9 1.6 1.2 1.1 1.4 1.5 1.8 1.9
Forced expiratory volume in 1-second (FEV1), Best measure 2.8 9.1 15.2 3.7 -3.6 -2.7 -2.8 -2.4 -1.8 -1.8 -3.6 -3.9 -2.2 -3.8 -1.3 -3.7 -1.6 1.7 0.7 3.3 3.3 3.8 3.1 3.3 3.8 3.7 3.5 3.5 2.5 2.7
Pulse wave Arterial Stiffness index 0.3 0.3 1.5 0.1 -0.2 -0.5 -0.5 -1.2 -0.4 -0.2 -0.1 -0.3 -0.5 -0.2 -1.2 -0.3 -0.9 -0.5 -0.6 0.6 0.5 0.1 0.8 0.6 0.2 0.1 0.2 0.4 0.6 0.9
Impedance of arm (left) 1.1 5.1 8.9 2.5 -2.4 -0.7 -2.6 -2.8 -0.5 -2.8 -3.0 -2.6 -2.1 -2.5 -2.2 -2.6 -0.6 1.8 1.6 2.6 1.8 2.6 2.2 2.7 2.7 2.6 2.2 1.9 0.9 2.3
Arm fat mass (right) 0.1 0.4 1.3 -0.5 0.4 0.4 0.8 -0.2 0.5 0.3 0.5 0.5 0.4 0.5 1.0 0.7 1.0 0.2 -0.6 -0.9 -0.5 -0.6 -1.0 -1.0 -0.7 -0.6 -0.7 -0.4 -0.3 -1.1
Trunk predicted mass 0.1 0.5 3.0 0.6 -0.8 -1.6 -0.5 -0.7 -0.8 -0.1 -0.1 -0.7 -0.7 -0.4 0.2 -0.6 -0.1 1.3 -1.7 0.3 0.6 0.5 0.3 0.3 0.5 0.5 0.5 0.7 0.7 0.1
Standing height 1.4 13.6 23.3 4.3 -4.5 -4.0 -4.0 -4.8 -2.0 -3.0 -4.0 -4.5 -4.2 -4.0 -2.6 -4.4 -1.2 3.6 -0.4 3.9 3.4 4.3 3.5 3.9 4.4 4.1 3.6 3.6 2.4 3.0
Length of working week for main job 4.0 4.4 8.4 -2.1 2.2 2.7 1.7 2.2 1.4 1.5 2.4 2.3 2.9 2.4 2.5 2.2 1.5 0.2 -0.1 -2.4 -2.0 -2.2 -2.5 -2.5 -2.2 -2.1 -2.1 -1.9 -1.6 -2.5
Exposure to tobacco smoke at home 1.1 1.3 2.3 1.4 -1.0 -0.6 -1.3 0.3 0.5 -1.4 -0.0 -1.4 -1.2 -1.5 -0.6 -1.5 -0.8 -0.8 0.8 1.3 1.3 1.4 1.2 1.2 1.4 1.3 1.2 1.4 1.1 1.0
Breastfed as a baby 3.7 4.6 6.4 -2.4 2.5 0.2 1.7 1.7 2.0 2.4 2.1 2.3 1.3 2.4 2.1 2.2 2.1 -2.4 0.7 -2.5 -2.2 -2.3 -2.5 -2.5 -2.3 -2.3 -2.5 -2.2 -1.9 -2.5
Tense / ‘highly strung’ 3.9 6.5 10.1 3.2 -3.1 -0.4 -2.8 -2.4 -1.0 -2.1 -2.5 -3.0 -3.0 -3.0 -2.8 -3.1 -0.9 0.6 2.1 2.8 2.3 3.1 2.5 2.9 3.1 3.1 2.8 2.4 1.4 2.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 4.8 0.4 -0.5 0.5 0.2 -0.9 1.5 -0.8 -0.7 -0.6 -1.0 -0.7 0.3 -0.7 1.3 0.9 2.2 0.1 0.1 0.6 -0.2 0.1 0.7 0.5 0.1 0.3 -0.3 -0.6
Hair/balding pattern: Pattern 4 6.1 14.9 38.2 -3.8 4.0 3.3 5.0 3.9 4.2 5.9 4.0 3.6 1.7 3.4 1.2 3.9 2.9 -6.2 1.1 -3.8 -4.1 -3.9 -3.8 -3.6 -3.9 -3.8 -3.9 -4.1 -3.8 -3.2
Birth weight of first child 0.2 0.4 1.4 0.3 -0.4 -0.7 -0.4 0.7 -0.7 -0.1 -0.3 -0.5 -0.6 -0.5 -0.0 -0.4 -1.2 -0.3 -1.0 0.6 0.8 0.4 0.7 0.5 0.4 0.5 0.7 0.8 0.9 0.7
Peak expiratory flow (PEF) 1.5 3.5 8.1 1.9 -1.9 -0.5 -1.6 -0.7 -1.4 -1.1 -1.7 -2.2 -1.4 -2.2 -0.0 -2.1 -2.2 0.9 -1.4 1.9 2.7 2.1 2.0 1.7 2.1 2.1 2.2 2.8 2.9 1.5
Pulse wave reflection index 1.9 2.4 7.2 1.2 -1.0 -0.4 -1.6 -1.0 -0.9 -0.9 -1.1 -1.5 -1.4 -1.3 -1.1 -1.4 -2.7 -0.3 -1.5 1.7 2.1 1.3 2.2 1.6 1.3 1.2 1.7 2.0 2.5 2.0
Ever highly irritable/argumentative for 2 days 0.9 1.1 3.2 1.4 -1.6 -0.6 -0.0 -1.4 -0.3 -0.4 -1.6 -1.2 -0.4 -1.3 -0.8 -1.1 0.8 0.8 1.8 0.9 0.5 1.3 0.4 0.9 1.2 1.4 1.0 0.8 -0.1 0.4
Loud music exposure frequency 0.5 0.6 2.3 0.7 -0.6 -0.6 -0.7 -1.3 -0.4 -0.6 -0.9 -0.4 -0.2 -0.6 -1.5 -0.6 0.0 1.3 1.0 0.9 0.2 0.7 0.6 0.9 0.6 0.8 0.7 0.3 -0.3 1.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 2.9 -0.3 0.4 -0.2 -0.1 0.7 -0.9 0.4 0.4 0.3 0.5 0.3 0.4 0.2 -1.0 0.7 -1.7 -0.1 0.5 -0.4 0.2 -0.2 -0.4 -0.3 0.0 0.4 1.0 0.2
Mouth/teeth dental problems: Bleeding gums 3.5 4.5 7.8 2.4 -1.5 -1.5 -2.1 -1.9 -0.5 -1.6 -1.7 -2.5 -2.2 -2.3 -1.9 -2.3 -2.0 -0.4 -0.5 2.6 2.4 2.4 2.6 2.7 2.3 2.4 2.6 2.3 2.0 2.8
Blood clot in the leg (DVT) 0.3 0.4 2.4 -0.2 0.3 -0.3 -0.1 0.9 -0.0 -0.3 0.7 0.1 1.3 0.1 1.5 0.1 0.2 -1.0 -0.2 -0.6 0.1 -0.3 -0.4 -0.7 -0.1 -0.4 -0.5 0.2 0.5 -1.0
Medication: Paracetamol 0.3 0.5 3.0 0.5 -0.8 -1.3 0.3 -0.8 0.8 -1.2 -0.6 -0.5 -0.5 -0.4 0.5 -0.4 1.4 -0.5 1.7 -0.2 -0.3 0.5 -0.6 -0.2 0.4 0.4 -0.1 -0.1 -0.6 -1.0
Headache pain in last month 0.3 0.6 4.5 -0.4 -0.2 -1.4 0.7 -0.7 0.1 1.2 -0.3 0.4 0.1 0.2 -0.6 0.2 1.0 1.0 2.1 -0.4 -0.8 -0.2 -0.5 -0.2 -0.2 -0.3 -0.5 -0.7 -1.1 -0.4
Medication for cholesterol, blood pressure or diabetes 0.3 0.5 2.5 0.3 0.2 1.3 -0.5 -1.2 -0.3 -1.0 -0.7 -0.4 0.7 -0.1 -1.6 -0.3 0.3 1.5 0.4 0.6 -0.3 0.4 0.4 0.8 0.4 0.4 0.2 -0.4 -0.9 0.9
Glaucoma (self-reported) 0.1 0.1 1.0 -0.1 -0.5 0.9 -0.1 -0.2 -0.3 -0.0 0.1 -0.1 -0.3 0.0 0.1 0.0 0.4 1.0 0.1 -0.2 0.0 0.1 -0.2 -0.2 0.1 0.0 -0.1 0.1 0.0 -0.4
Gout (self-reported) 0.6 0.8 1.7 1.1 -1.2 -0.5 -0.6 -0.1 -0.3 -0.7 -0.9 -1.3 -0.9 -1.1 0.1 -1.2 -0.3 0.3 -0.0 0.8 1.2 1.1 0.7 0.7 1.2 1.1 1.0 1.3 1.1 0.4
Hypothyroidism/myxoedema (self-reported) 2.8 5.5 9.7 2.4 -2.1 -1.5 -2.5 -0.7 -2.0 -1.6 -1.9 -2.4 -3.1 -2.4 -2.5 -2.6 -2.1 1.8 -0.9 2.8 2.6 2.6 2.7 2.7 2.5 2.6 2.8 2.6 2.3 2.8
Medication: Amlodipine 1.9 2.6 5.0 -1.7 1.3 0.7 1.7 0.4 1.7 2.2 1.3 1.8 1.0 1.7 1.0 1.7 1.5 -0.1 1.1 -1.9 -2.0 -1.8 -1.9 -1.8 -1.7 -1.8 -2.0 -1.9 -1.8 -1.8
Medication: Ventolin 100micrograms inhaler 0.3 0.4 3.7 0.2 0.3 -0.2 0.4 0.3 -0.1 -0.6 0.1 0.1 1.1 0.1 -0.5 0.2 1.6 -0.2 1.9 -0.3 -0.7 -0.0 -0.5 -0.2 -0.1 0.0 -0.2 -0.7 -1.1 -0.3
Birth weight 1.5 3.3 6.2 -2.2 1.9 1.3 1.9 1.3 2.0 1.2 1.9 1.8 1.0 1.7 2.3 1.6 1.8 -1.4 -0.1 -2.2 -1.9 -1.8 -2.1 -2.2 -1.7 -2.0 -2.2 -1.9 -1.7 -2.5
Chronic bronchitis/emphysema (mother) 0.6 0.8 4.2 -0.6 0.1 1.5 0.9 1.0 -0.6 -0.7 -0.1 1.0 2.0 0.8 0.7 0.9 0.6 0.4 0.7 -0.9 -0.7 -0.7 -1.1 -1.0 -0.8 -0.6 -0.6 -0.6 -0.5 -1.0
High blood pressure (siblings) 0.2 0.2 0.6 0.5 -0.6 -0.5 -0.2 0.2 -0.4 0.0 0.1 -0.5 -0.7 -0.5 -0.3 -0.6 -0.8 -0.5 -0.2 0.4 0.7 0.5 0.5 0.4 0.5 0.3 0.4 0.6 0.8 0.3
Forced vital capacity (FVC), Best measure 3.0 11.0 17.8 4.1 -4.1 -3.2 -3.4 -2.8 -2.3 -2.2 -3.9 -4.2 -2.5 -3.9 -1.4 -4.0 -1.8 1.8 0.3 3.6 3.6 4.1 3.4 3.5 4.0 4.1 3.8 3.8 2.9 2.9
Body fat percentage 0.2 0.6 2.7 1.0 -1.0 -0.1 -0.4 -1.6 0.3 -1.0 -0.8 -0.9 -0.9 -1.0 -0.2 -0.8 0.2 1.1 0.3 0.6 0.7 0.9 0.4 0.6 0.9 0.9 0.7 0.8 0.5 0.2
Leg fat percentage (right) 0.5 1.8 3.8 1.7 -1.6 -0.9 -0.9 -2.0 -0.0 -1.0 -1.2 -1.6 -1.3 -1.8 -0.9 -1.6 -0.4 1.4 0.6 1.4 1.5 1.7 1.2 1.3 1.6 1.6 1.5 1.5 1.2 1.0
Arm fat-free mass (right) 0.1 0.4 3.2 0.4 -0.6 -1.2 -0.2 -0.5 -1.0 -0.1 -0.1 -0.5 -0.8 -0.3 0.6 -0.4 -0.3 1.3 -1.8 0.1 0.6 0.3 0.2 0.0 0.3 0.2 0.3 0.6 0.8 -0.2
Exposure to tobacco smoke outside home 0.5 0.7 5.2 -0.7 0.6 0.3 1.0 1.5 1.7 1.1 0.5 0.2 -0.2 0.3 0.9 0.2 0.6 -2.3 0.2 -0.5 -0.5 -0.3 -0.5 -0.5 -0.2 -0.4 -0.6 -0.4 -0.5 -0.7
Comparative body size at age 10 4.4 12.1 18.2 -4.3 4.1 2.0 3.4 3.1 1.5 3.1 3.6 4.1 3.2 4.1 2.9 4.2 1.7 -3.0 -0.8 -3.9 -3.7 -4.2 -3.6 -3.9 -4.2 -4.3 -4.0 -3.9 -2.8 -3.4
Number of full brothers 0.7 0.9 4.8 1.4 -1.2 -0.4 -0.5 0.3 0.8 -1.4 -0.3 -1.2 -1.4 -1.2 -0.3 -1.1 0.8 -0.4 2.2 0.8 0.4 1.2 0.2 0.8 1.2 1.3 0.8 0.6 -0.2 0.2
Worry too long after embarrassment 0.1 0.2 2.1 0.2 0.1 0.6 -0.0 -0.4 0.2 0.4 -0.1 -0.2 0.4 -0.1 0.8 -0.1 0.0 -1.5 -0.0 -0.1 0.3 0.2 -0.1 -0.2 0.1 0.1 0.1 0.3 0.5 -0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.7 2.2 6.2 1.9 -1.5 -0.1 -0.6 -1.4 0.6 -1.9 -1.7 -1.8 -2.1 -1.8 -2.0 -1.7 1.1 -0.4 2.5 1.5 0.6 1.8 1.0 1.7 1.8 1.8 1.4 0.8 -0.4 1.2
Wheeze or whistling in the chest in last year 0.2 0.3 2.1 -0.3 0.1 -0.8 -0.2 1.5 0.2 -0.2 0.6 0.5 0.6 0.6 0.6 0.5 -0.4 -0.3 -0.5 -0.5 -0.1 -0.5 -0.3 -0.6 -0.6 -0.6 -0.3 -0.2 0.3 -0.5
Number of children fathered 0.3 0.3 2.6 0.4 -0.5 -1.6 -0.8 0.3 0.1 -0.1 0.2 -0.2 -0.5 -0.1 1.3 -0.4 0.1 0.5 -0.2 0.0 0.7 0.4 -0.1 -0.2 0.3 0.4 0.4 0.8 0.9 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 2.3 1.3 -1.4 -0.2 -1.4 -1.2 0.0 -1.1 -0.2 -1.3 -0.2 -1.1 0.1 -1.1 -0.4 1.4 0.4 0.9 1.3 1.1 0.7 0.7 1.1 1.3 1.2 1.5 1.4 0.5
Age at first live birth 0.1 0.1 0.9 -0.2 0.3 -0.2 -0.1 0.1 -0.4 1.0 0.3 0.3 0.2 0.3 -0.5 0.4 0.1 -0.3 -0.4 -0.2 -0.3 -0.3 -0.1 -0.1 -0.3 -0.3 -0.2 -0.3 -0.3 0.0
Pulse wave peak to peak time 0.2 0.2 1.0 0.2 -0.2 0.2 0.1 0.9 0.2 -0.1 -0.2 -0.0 0.2 -0.0 1.0 -0.0 0.7 0.7 0.6 -0.3 -0.2 0.2 -0.6 -0.3 0.1 0.2 0.0 -0.1 -0.4 -0.7
Health satisfaction 0.4 0.5 2.5 -0.2 0.2 0.7 1.0 0.7 1.2 1.1 0.1 0.3 -1.2 -0.1 1.6 0.1 0.6 -1.3 -0.1 -0.6 0.0 -0.1 -0.6 -0.7 -0.1 -0.2 -0.3 0.1 0.3 -1.2
Shortness of breath walking on level ground 0.2 0.2 3.8 0.2 0.1 0.4 0.4 -0.4 -0.2 0.4 -0.5 -0.2 0.0 -0.4 0.5 -0.3 0.6 -1.9 0.5 -0.1 0.1 0.2 -0.1 -0.1 0.3 0.1 -0.1 0.2 0.0 -0.4
Qualifications: College or University degree 0.5 1.5 8.0 0.4 -0.4 -1.2 -1.5 -1.6 -2.5 0.2 -1.4 -0.3 -0.6 -0.1 -0.9 -0.3 -2.1 1.8 -2.8 0.8 1.0 0.2 1.2 0.8 0.2 0.2 0.7 0.7 1.3 1.4
Eye problems/disorders: None of the above 0.6 0.7 3.2 -0.6 1.1 0.6 0.5 -0.3 -0.2 1.1 -0.2 0.5 1.8 0.7 0.3 0.8 1.0 -1.8 0.6 -0.7 -0.9 -0.6 -0.8 -0.6 -0.7 -0.6 -0.6 -0.9 -1.0 -0.6
Mouth/teeth dental problems: Loose teeth 2.9 3.5 13.0 -1.7 1.8 0.9 2.1 1.8 3.1 3.0 2.3 1.4 0.3 1.7 1.1 1.6 1.4 -3.6 0.8 -1.7 -1.8 -1.6 -1.6 -1.6 -1.6 -1.8 -1.8 -1.8 -1.6 -1.5
Emphysema/chronic bronchitis 0.2 0.2 3.5 -0.1 -0.0 0.3 -0.2 0.1 -0.1 -0.5 -0.6 -0.0 -0.3 0.1 0.4 -0.1 -0.5 -1.9 -0.5 -0.0 0.4 -0.0 0.1 -0.1 -0.0 -0.0 0.1 0.4 0.7 -0.1
Medication for pain relief, constipation, heartburn 0.6 1.0 3.7 0.4 -0.3 1.0 -1.3 -0.0 -1.9 0.1 -0.3 -0.3 -0.0 -0.2 -1.2 -0.3 -1.9 1.2 -1.6 1.0 0.9 0.4 1.3 1.0 0.3 0.4 0.9 0.8 1.1 1.6
Neck or shoulder pain in last month 0.2 0.2 1.0 0.2 -0.7 -0.5 -0.8 0.3 -0.6 -0.1 0.4 0.0 -1.0 -0.0 -0.4 -0.1 -1.0 0.1 -0.8 0.3 0.4 0.1 0.5 0.3 0.1 0.1 0.3 0.3 0.5 0.5
Medication: Blood pressure 2.7 4.7 8.4 -2.4 1.6 1.0 2.6 1.7 1.6 2.9 2.3 2.4 0.9 2.2 2.4 2.4 1.6 -2.0 0.2 -2.7 -2.0 -2.5 -2.6 -2.9 -2.4 -2.4 -2.5 -1.9 -1.4 -2.9
Angina (self-reported) 2.1 2.7 8.9 -1.9 1.8 1.0 1.5 1.1 0.4 3.0 1.7 2.0 1.0 2.0 1.6 2.0 0.7 -1.0 -0.9 -1.9 -1.5 -2.0 -1.6 -1.9 -2.0 -2.0 -1.9 -1.6 -1.0 -1.5
Migraine (self-reported) 1.2 1.5 2.9 1.4 -1.3 -1.2 -1.3 -1.0 -1.0 -1.7 -0.9 -1.2 -1.5 -1.4 -0.6 -1.4 -0.4 1.7 0.9 1.2 1.2 1.4 1.1 1.2 1.4 1.4 1.2 1.3 1.0 0.9
Medication: Ibuprofen 0.4 0.4 1.2 0.7 -0.5 -0.4 -0.2 -0.5 -0.2 -0.3 -0.9 -0.7 -0.9 -0.6 -0.1 -0.7 -0.9 0.3 -1.1 0.6 0.9 0.6 0.8 0.5 0.6 0.5 0.8 0.8 1.1 0.5
Medication: Allopurinol 0.4 0.5 1.3 0.9 -1.0 -0.3 -0.4 -0.7 -0.2 -0.6 -1.2 -0.9 -0.4 -0.9 0.1 -0.9 0.7 -0.1 0.8 0.5 0.5 0.9 0.2 0.5 1.0 1.0 0.6 0.8 0.2 0.0
Medication: Omeprazole 0.3 0.3 1.1 -0.5 0.5 0.4 0.4 0.9 1.1 -0.7 0.6 0.5 0.2 0.4 0.4 0.5 0.2 -1.0 0.5 -0.5 -0.4 -0.5 -0.5 -0.6 -0.5 -0.5 -0.4 -0.4 -0.2 -0.6
Medication: Seretide 50 evohaler 0.3 0.4 4.0 0.1 0.1 -0.5 -0.5 1.2 -0.5 -0.8 0.4 -0.1 1.8 0.0 0.2 0.1 -0.4 -2.0 0.1 0.1 0.2 -0.0 0.1 -0.0 -0.1 0.0 0.1 0.2 0.3 0.2
Mean time to correctly identify matches 0.1 0.2 1.3 0.2 -0.4 -1.1 0.0 -0.9 0.2 0.8 -0.4 -0.2 -0.0 -0.3 -0.1 -0.4 0.6 0.4 1.1 0.2 0.1 0.4 0.2 0.3 0.5 0.4 0.2 0.1 -0.2 0.1
Heart disease (mother) 0.3 0.3 2.6 0.3 -0.7 -0.3 0.1 -0.3 0.8 -0.6 0.1 -0.4 -0.3 -0.5 -0.6 -0.6 0.9 1.1 1.6 0.3 -0.2 0.5 0.0 0.3 0.5 0.4 0.1 -0.0 -0.6 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.1 0.1 1.6 -0.1 -0.2 1.3 -0.3 0.3 0.1 -0.3 -0.1 -0.2 0.4 -0.1 0.6 -0.2 -0.2 0.7 0.3 -0.2 0.2 -0.0 0.1 -0.2 0.2 -0.2 -0.3 0.2 0.3 -0.4
Whole body fat mass 0.1 0.5 2.4 0.9 -0.9 -0.5 -0.3 -1.5 0.2 -0.7 -0.7 -0.9 -1.0 -0.9 0.1 -0.8 0.5 1.1 -0.1 0.4 0.6 0.8 0.3 0.4 0.8 0.8 0.6 0.8 0.5 -0.0
Leg fat mass (right) 0.3 1.1 2.8 1.3 -1.3 -0.7 -0.5 -1.7 -0.1 -1.0 -1.1 -1.3 -1.4 -1.4 -0.2 -1.2 0.1 1.4 -0.0 0.9 1.1 1.3 0.7 0.8 1.3 1.2 1.0 1.2 0.9 0.3
Arm predicted mass (right) 0.1 0.4 4.0 0.2 -0.4 -1.0 -0.2 -0.5 -0.9 0.0 0.1 -0.4 -0.7 -0.1 0.6 -0.2 -0.3 1.3 -2.0 -0.0 0.5 0.1 0.1 -0.1 0.2 0.1 0.1 0.5 0.8 -0.3
Pulse rate, automated reading 1.0 3.2 8.0 -1.5 1.1 0.5 2.2 1.4 0.7 1.1 1.3 1.6 1.5 1.7 1.3 1.9 2.8 -1.1 1.8 -2.1 -2.2 -1.7 -2.5 -2.0 -1.8 -1.6 -2.0 -2.1 -2.3 -2.3
Alcohol intake frequency. 0.4 1.0 2.3 -0.5 0.2 0.7 1.2 1.3 1.5 0.9 1.0 0.5 1.5 0.7 -0.0 0.8 1.4 -0.5 1.4 -0.8 -1.3 -0.7 -1.2 -0.8 -0.7 -0.6 -0.9 -1.2 -1.5 -0.9
Comparative height size at age 10 0.1 0.4 2.5 -0.3 -0.4 -1.1 0.2 -0.2 -0.6 0.5 0.1 -0.0 0.4 0.3 1.1 0.2 -0.2 1.5 -1.6 -0.4 0.2 -0.3 -0.1 -0.5 -0.2 -0.4 -0.3 0.2 0.5 -0.5
Number of full sisters 1.4 1.7 4.6 -1.4 2.1 1.2 1.2 1.5 1.2 0.1 1.7 1.3 1.0 1.2 0.7 1.2 1.0 -2.1 0.3 -1.2 -1.4 -1.3 -1.2 -1.2 -1.2 -1.3 -1.4 -1.5 -1.3 -1.2
Suffer from ‘nerves’ 0.6 0.9 2.1 1.1 -1.2 -0.5 -0.9 -0.9 -0.1 0.1 -0.7 -1.1 -1.2 -1.1 -1.0 -1.1 -0.3 -1.1 1.4 1.0 0.8 1.2 0.9 1.0 1.1 1.1 1.1 0.8 0.5 0.8
Overall health rating 0.5 1.0 2.5 1.2 -1.1 -1.0 -0.1 -0.4 -0.1 -0.9 -1.1 -1.1 -1.5 -1.5 -1.3 -1.2 0.5 -0.8 1.6 0.9 0.6 1.3 0.6 1.0 1.3 1.2 0.9 0.7 -0.0 0.5
Chest pain or discomfort 0.4 0.5 1.9 0.6 -0.4 0.7 -0.3 -0.6 0.9 -0.8 0.0 -0.6 -1.4 -0.7 -0.8 -0.7 -0.9 -1.0 0.4 0.8 0.7 0.6 0.9 0.8 0.6 0.6 0.7 0.7 0.7 0.9
Had major operations 1.0 1.2 3.0 0.8 -0.9 -1.3 -0.9 0.4 -0.5 -1.7 -0.9 -1.2 -0.7 -1.3 0.4 -1.4 -1.6 -0.4 -0.1 1.0 1.6 1.2 1.2 0.9 1.3 1.0 1.1 1.5 1.7 0.6
Age at last live birth 0.2 0.2 2.6 0.3 0.1 -0.8 -1.0 0.4 -0.4 -0.1 0.3 -0.3 0.5 -0.1 -0.4 -0.2 -0.2 -1.6 -0.8 0.3 0.2 0.2 0.4 0.3 0.2 0.2 0.3 0.2 0.2 0.4
Family relationship satisfaction 0.1 0.2 1.3 0.3 0.4 0.6 -0.2 -0.2 -1.1 0.8 -0.4 -0.1 0.5 0.1 0.5 0.1 -0.3 -0.5 -0.4 0.1 0.4 0.1 0.1 0.0 0.0 0.2 0.3 0.4 0.6 0.1
Leg pain on walking 0.5 0.6 2.2 -0.5 0.7 0.6 0.7 1.1 0.9 1.3 1.1 0.7 0.6 0.6 1.5 0.5 1.1 0.2 0.5 -0.9 -0.5 -0.5 -0.9 -0.9 -0.5 -0.5 -0.6 -0.4 -0.4 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.9 0.8 -0.1 0.4 -0.7 0.3 1.0 -0.1 0.2 -0.8 -0.6 -0.6 0.4 -0.8 0.6 -0.1 0.2 0.4 0.5 0.8 0.1 0.3 0.8 0.9 0.7 0.7 0.3 0.0
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.8 -0.1 0.3 0.0 0.1 -0.8 -0.7 0.4 -0.7 0.3 0.8 0.1 -0.3 0.1 0.4 -0.5 0.9 -0.0 -0.4 -0.1 -0.2 0.0 -0.1 0.0 -0.0 -0.4 -0.6 0.1
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.3 0.1 -0.8 -0.9 -0.5 -1.1 -0.1 0.1 -0.9 -0.3 -0.5 -0.3 -0.5 -0.4 -0.6 1.2 -0.4 0.6 0.5 0.4 0.7 0.6 0.4 0.4 0.5 0.5 0.5 0.8
Medication: Aspirin 0.4 0.5 2.3 -0.4 0.5 -0.6 1.0 -0.6 1.5 0.8 0.1 0.1 -0.3 0.0 1.5 0.1 1.3 -0.7 0.8 -0.7 -0.5 -0.2 -0.8 -0.8 -0.1 -0.4 -0.7 -0.3 -0.5 -1.3
Supplements: Vitamin C 0.1 0.2 1.2 -0.2 0.0 -0.3 0.1 -0.9 -1.1 0.7 -0.6 0.1 -0.3 0.2 -0.4 0.2 -0.4 0.9 0.1 0.0 0.0 -0.2 0.2 0.0 -0.1 -0.2 -0.1 -0.0 0.1 0.3
Knee pain experienced in last month 1.2 1.8 3.5 -1.8 1.5 1.1 1.3 1.9 0.9 1.1 1.6 1.7 0.8 1.6 1.0 1.5 0.5 -0.1 -0.8 -1.6 -1.3 -1.6 -1.2 -1.5 -1.6 -1.7 -1.5 -1.4 -0.9 -1.3
Hypertension (Self-reported) 1.6 4.4 10.7 -1.5 0.9 0.9 3.3 1.3 3.1 2.8 1.8 1.4 0.4 1.3 1.0 1.6 3.2 -0.4 2.9 -2.3 -2.4 -1.6 -2.6 -2.2 -1.6 -1.6 -2.2 -2.1 -2.5 -2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.5 0.2 -0.6 1.2 -0.4 0.7 0.1 -0.4 -0.1 -0.5 -0.4 -0.6 -0.5 -0.6 -1.1 -0.6 -0.5 0.6 0.7 0.5 0.9 0.7 0.6 0.3 0.5 0.6 0.7 0.7
Illnesses of father: Heart disease 1.5 2.1 6.7 1.5 -1.4 -0.7 -0.8 -1.6 0.2 -2.0 -1.5 -1.6 -1.9 -2.0 -2.6 -1.6 0.2 0.7 1.2 1.7 0.7 1.7 1.4 1.9 1.8 1.6 1.3 0.7 -0.2 1.5
Illnesses of siblings: Diabetes 0.3 0.4 2.0 0.3 -0.3 0.7 0.5 -0.1 0.6 -0.8 0.1 -0.3 0.6 -0.3 0.0 -0.2 1.4 -1.3 1.4 -0.2 -0.4 0.3 -0.5 -0.1 0.3 0.2 -0.2 -0.3 -0.8 -0.7
Smoking status: Previous 1.4 2.1 3.6 -1.9 1.7 0.2 1.4 0.8 1.7 1.2 1.9 1.7 0.7 1.7 1.6 1.4 0.9 -0.5 -0.5 -1.7 -1.4 -1.7 -1.4 -1.7 -1.6 -1.8 -1.7 -1.4 -0.9 -1.6
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.4 6.7 2.3 -2.2 -2.1 -1.7 -2.4 -1.2 -1.7 -2.1 -2.1 -1.3 -1.9 -2.6 -2.0 0.0 1.6 0.3 2.1 1.2 2.1 1.7 2.2 2.1 2.1 1.8 1.3 0.3 1.9
Whole body fat-free mass 0.1 0.3 3.9 -0.0 -0.1 -0.9 0.1 -0.3 -0.8 0.3 0.2 -0.1 -0.2 0.2 0.9 0.1 0.3 0.8 -2.0 -0.4 0.0 -0.1 -0.3 -0.4 -0.1 -0.2 -0.2 0.1 0.2 -0.6
Leg fat-free mass (right) 0.3 1.6 4.0 -1.2 1.2 0.6 1.2 0.5 0.0 1.0 1.1 1.0 0.6 1.4 2.0 1.3 1.3 -0.3 -2.0 -1.6 -1.1 -1.3 -1.6 -1.7 -1.3 -1.3 -1.4 -1.1 -0.8 -1.9
Arm fat percentage (left) 0.1 0.3 1.1 -0.5 0.5 0.8 0.6 -0.4 0.5 -0.1 0.4 0.5 0.3 0.4 1.0 0.6 0.6 0.3 -0.4 -0.8 -0.4 -0.6 -0.8 -0.9 -0.6 -0.6 -0.6 -0.3 -0.1 -0.9
Average weekly red wine intake 0.3 0.4 1.7 -0.7 0.6 0.1 -1.1 1.1 -0.2 0.5 0.7 0.4 -0.3 0.5 0.3 0.2 -1.3 1.1 -1.2 -0.1 0.3 -0.5 0.4 -0.1 -0.3 -0.6 -0.3 0.1 0.7 0.2
Handedness (chirality/laterality): Left-handed 1.6 1.9 7.1 1.4 -1.5 -2.0 -0.8 -1.6 -0.0 -1.1 -1.5 -1.4 -2.1 -1.4 -0.9 -1.6 0.2 2.7 1.2 1.3 0.9 1.6 1.0 1.4 1.6 1.6 1.3 1.0 0.3 0.9
Mood swings 0.6 1.1 5.0 -0.8 1.0 2.2 1.2 0.6 1.6 0.3 0.9 0.7 -0.3 0.7 0.2 0.8 1.4 -0.8 1.3 -0.9 -1.2 -0.6 -1.1 -0.8 -0.7 -0.8 -1.0 -1.3 -1.5 -1.1
Loneliness, isolation 0.4 0.5 3.2 -0.4 0.7 1.8 0.6 -0.1 0.7 -0.5 0.6 0.1 0.1 0.3 -0.1 0.2 0.7 -1.0 1.8 -0.3 -0.7 -0.3 -0.4 -0.3 -0.2 -0.4 -0.6 -0.7 -1.0 -0.4
Long-standing illness, disability or infirmity 0.4 0.7 2.1 -0.5 0.7 -0.6 1.1 1.0 0.1 0.2 0.1 0.7 1.1 0.5 1.1 0.7 1.0 -1.4 0.9 -1.0 -0.6 -0.7 -1.0 -1.1 -0.7 -0.7 -0.7 -0.5 -0.4 -1.2
Ever had bowel cancer screening 1.4 1.6 6.2 -1.3 1.2 1.7 0.3 1.1 0.2 1.8 1.2 1.2 0.8 1.4 2.0 1.3 -0.5 -2.2 -2.5 -1.1 -0.3 -1.3 -0.8 -1.3 -1.4 -1.2 -0.8 -0.4 0.4 -0.8
Diabetes diagnosed by doctor 0.7 1.2 5.4 -0.5 0.2 -0.1 2.1 -0.1 1.1 0.4 0.3 0.4 0.3 0.1 1.2 0.5 2.1 -0.5 2.3 -1.2 -1.1 -0.5 -1.4 -1.1 -0.4 -0.6 -1.1 -0.9 -1.3 -1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 1.2 0.8 -0.5 -1.1 -0.4 -0.7 0.2 -1.0 -0.3 -0.8 -0.3 -0.7 -0.9 -0.6 -0.2 -0.5 0.5 0.7 0.5 0.6 0.6 0.7 0.6 0.8 0.7 0.6 0.3 0.8
Friendships satisfaction 1.6 2.0 7.7 -1.4 2.1 2.0 0.6 1.7 -0.2 1.8 1.5 1.4 1.3 1.3 2.8 1.3 -0.2 -1.6 -1.4 -1.4 -0.4 -1.3 -0.9 -1.5 -1.3 -1.4 -1.1 -0.4 0.5 -1.5
Qualifications: nursing, teaching 1.4 2.2 11.2 0.7 -1.1 -2.0 -1.5 -1.5 -3.3 -0.4 -1.3 -0.8 -0.8 -0.7 -0.6 -0.8 -2.8 0.8 -2.4 1.2 1.6 0.7 1.6 1.1 0.7 0.6 1.1 1.4 2.1 1.5
Commuting to job workplace: Walk 0.7 0.8 4.2 -0.6 0.7 0.5 0.4 2.0 2.0 0.1 1.5 0.5 0.4 0.7 1.4 0.6 0.4 0.3 -0.6 -0.9 -0.4 -0.7 -0.8 -1.0 -0.6 -0.7 -0.7 -0.3 -0.1 -1.1
Eye problems/disorders: Cataract 0.9 1.1 2.9 1.1 -1.1 -1.2 -0.9 -0.1 0.2 -1.0 -0.3 -0.7 -1.7 -0.8 -0.6 -0.9 -1.3 1.6 -1.2 1.1 1.3 0.9 1.2 1.0 0.9 0.8 1.1 1.2 1.4 1.2
Mouth/teeth dental problems: Mouth ulcers 1.3 2.1 4.1 1.4 -1.4 -1.3 -1.1 -0.8 -1.0 -2.0 -1.4 -1.4 -1.8 -1.4 -0.8 -1.5 -2.0 1.1 -0.8 1.5 1.9 1.4 1.7 1.4 1.4 1.2 1.5 1.7 2.0 1.2
Medication for cholesterol 0.8 1.3 12.5 -0.6 1.1 0.2 -1.0 1.0 -2.0 -0.1 0.2 0.7 0.3 0.6 1.2 0.6 -2.1 -1.4 -3.5 -0.1 0.7 -0.5 0.5 -0.2 -0.6 -0.6 0.1 0.5 1.6 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.7 0.7 -0.6 0.3 -0.9 0.2 -1.1 -0.3 -0.4 -0.6 -0.6 -0.8 -1.0 -0.7 -1.3 0.0 0.2 0.9 1.1 0.7 1.0 0.8 0.7 0.9 1.1 1.1 1.2 1.2
Back pain experienced in last month 0.3 0.4 5.7 -0.2 0.6 0.4 0.6 0.9 0.5 0.3 0.3 0.1 0.1 0.2 0.9 0.1 0.8 -2.4 0.7 -0.4 -0.4 -0.2 -0.5 -0.4 -0.1 -0.2 -0.4 -0.3 -0.4 -0.8
Mineral and other dietary supplements 0.1 0.1 1.6 0.1 0.3 1.2 0.4 1.0 0.4 -0.3 0.4 0.1 0.5 0.0 -0.1 0.0 0.2 0.2 0.1 0.1 -0.2 0.0 -0.1 0.1 0.0 0.1 0.0 -0.2 -0.3 0.1
Breast cancer (self-reported) 1.3 1.5 2.6 -1.2 1.2 -0.7 0.9 1.3 0.6 1.0 0.6 1.4 0.9 1.4 1.6 1.3 1.6 0.5 -0.1 -1.5 -1.4 -1.3 -1.6 -1.5 -1.3 -1.2 -1.4 -1.2 -1.2 -1.6
Asthma (self-reported) 0.6 1.3 7.3 1.1 -1.1 -0.2 -1.8 -0.4 -2.1 -2.7 -1.0 -0.5 0.2 -0.5 -0.6 -0.7 -1.3 0.8 -0.8 0.8 1.2 0.7 1.0 0.7 0.6 0.8 1.1 1.2 1.5 0.9
Osteoporosis (self-reported) 0.5 0.6 2.4 0.5 -0.1 0.0 -0.5 -0.0 -0.5 -1.2 -0.7 -0.5 -0.8 -0.8 -0.2 -0.6 -1.1 -1.6 -1.1 0.7 0.9 0.6 0.9 0.6 0.6 0.4 0.6 0.8 1.0 0.6
Osteoarthritis (self-reported) 0.1 0.2 0.7 -0.5 -0.3 0.1 -0.1 -0.1 -0.3 -0.4 0.1 0.5 0.9 0.4 -0.4 0.3 -0.3 0.8 -0.6 -0.2 -0.2 -0.5 -0.1 -0.2 -0.4 -0.5 -0.3 -0.3 0.0 -0.0
Medication: Aspirin 0.6 0.7 2.3 -0.6 0.7 -0.2 1.2 -0.6 1.5 0.6 0.2 0.5 -0.2 0.4 1.4 0.4 1.3 -1.1 0.7 -1.0 -0.8 -0.6 -1.0 -1.0 -0.5 -0.7 -0.9 -0.7 -0.8 -1.4
Medication: Gliclazide 0.4 0.5 1.3 -0.5 0.1 -1.0 0.8 0.1 -0.7 0.6 -0.3 0.5 0.8 0.5 -0.0 0.5 0.8 1.1 0.9 -0.7 -0.8 -0.6 -0.7 -0.6 -0.5 -0.6 -0.8 -0.7 -0.8 -0.8
Illnesses of father: None of the above (group 1) 0.2 0.2 1.6 -0.0 -0.1 -0.1 0.3 0.0 -0.8 0.2 -0.1 -0.0 1.2 0.1 1.2 0.0 -0.3 -0.1 -0.6 -0.2 0.3 -0.1 -0.1 -0.3 -0.1 -0.1 -0.0 0.3 0.6 -0.4
Smoking status: Current 0.5 0.8 6.0 -0.2 0.2 0.3 1.0 0.2 1.5 1.1 0.3 0.4 0.6 0.2 0.3 0.3 1.5 -0.6 2.4 -0.6 -1.0 -0.3 -0.9 -0.5 -0.3 -0.3 -0.7 -0.8 -1.3 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.8 4.5 1.7 -1.5 -2.1 -1.3 -0.9 -1.0 -0.2 -1.6 -2.1 -0.5 -1.9 -0.8 -1.9 -1.4 1.9 -0.1 2.0 1.9 2.0 2.0 2.0 1.9 2.0 2.1 2.0 1.6 2.0
Whole body water mass 0.1 0.3 4.3 -0.1 -0.1 -0.9 0.1 -0.3 -0.8 0.4 0.3 -0.0 -0.2 0.3 0.9 0.1 0.2 0.9 -2.1 -0.4 0.1 -0.2 -0.3 -0.5 -0.2 -0.2 -0.2 0.1 0.3 -0.7
Leg predicted mass (right) 0.3 1.5 3.9 -1.2 1.1 0.5 1.1 0.5 -0.0 1.0 1.1 1.0 0.6 1.3 2.0 1.2 1.4 -0.3 -1.9 -1.6 -1.1 -1.2 -1.5 -1.6 -1.2 -1.3 -1.4 -1.0 -0.7 -1.9
Arm fat mass (left) 0.1 0.4 1.2 -0.4 0.4 0.2 0.7 -0.4 0.5 0.2 0.4 0.4 0.2 0.4 1.1 0.6 0.9 0.4 -0.5 -0.8 -0.5 -0.5 -0.9 -0.9 -0.6 -0.5 -0.6 -0.4 -0.3 -1.1
Number of self-reported non-cancer illnesses 0.4 0.7 2.4 0.8 -1.2 -1.2 -0.2 -0.9 -0.3 -0.6 -1.2 -1.0 -1.5 -0.9 0.1 -1.0 0.0 0.3 0.9 0.4 0.9 0.8 0.4 0.3 0.9 0.8 0.6 1.1 1.0 -0.2
Average weekly champagne plus white wine intake 2.8 3.9 6.3 -2.5 2.4 2.2 2.3 2.0 0.4 1.6 1.8 2.1 1.8 2.1 1.6 2.3 1.1 -2.0 -1.1 -2.1 -2.0 -2.3 -2.0 -2.1 -2.3 -2.2 -2.1 -2.0 -1.5 -1.7
Miserableness 1.7 2.9 5.5 -1.6 1.7 2.0 1.9 1.0 1.6 1.5 1.1 1.6 1.2 1.6 0.2 1.6 2.4 -1.8 1.2 -1.7 -2.2 -1.6 -1.9 -1.6 -1.6 -1.6 -1.8 -2.2 -2.3 -1.7
Guilty feelings 1.0 1.5 3.7 1.3 -1.4 -0.6 -0.9 -1.1 -0.2 -1.2 -1.2 -1.4 -1.9 -1.5 -1.6 -1.5 -0.3 0.2 1.7 1.4 0.9 1.5 1.2 1.5 1.6 1.3 1.0 0.8 0.3 1.1
Wears glasses or contact lenses 1.0 1.1 3.5 1.0 -0.8 -1.0 -1.6 -0.7 -0.7 -1.0 -0.9 -1.1 -1.9 -0.9 -0.4 -1.2 -0.9 0.3 -0.4 1.2 1.2 1.2 1.2 1.1 1.2 1.1 1.1 1.2 1.1 1.0
Ever taken oral contraceptive pill 0.2 0.2 1.1 -0.4 -0.2 -0.9 0.1 0.5 0.4 -0.1 0.7 0.4 0.3 0.5 0.5 0.4 -0.6 0.7 -1.1 -0.4 0.1 -0.5 -0.3 -0.5 -0.5 -0.4 -0.2 0.1 0.5 -0.3
Hearing aid user 1.1 1.3 3.7 -0.8 0.3 0.1 1.4 1.0 1.4 1.8 1.2 1.1 0.3 1.1 0.3 1.0 1.9 0.8 1.1 -1.1 -1.4 -0.9 -1.4 -1.1 -1.0 -0.8 -0.9 -1.3 -1.5 -1.1
Mother’s age at death 0.4 0.5 5.8 -0.6 0.6 -0.6 0.4 0.6 -0.0 0.3 0.3 0.2 0.7 0.2 2.4 0.2 -0.6 -0.9 -1.4 -0.6 0.3 -0.3 -0.3 -0.7 -0.3 -0.5 -0.3 0.3 0.9 -0.9
Financial situation satisfaction 1.5 1.9 3.7 1.6 -1.4 -0.3 -1.2 -0.6 -1.5 -1.5 -1.2 -1.7 -1.5 -1.9 -0.5 -1.8 -0.3 1.1 1.0 1.4 1.5 1.8 1.3 1.4 1.8 1.6 1.4 1.6 1.2 0.8
Tinnitus: Yes, now most or all of the time 1.4 1.7 6.5 -1.6 1.2 2.5 0.9 0.8 0.8 0.9 1.3 1.3 1.6 1.4 1.0 1.4 0.7 -0.7 -0.8 -1.3 -1.3 -1.5 -1.2 -1.3 -1.4 -1.5 -1.5 -1.3 -1.0 -1.2
Commuting to job workplace: Public transport 0.5 0.6 3.7 0.4 -0.3 0.7 -0.4 -0.2 -1.3 -0.9 -0.5 -0.5 -0.5 -0.4 -0.8 -0.3 -1.6 -0.2 -1.9 0.8 0.8 0.3 1.0 0.7 0.3 0.3 0.6 0.7 1.0 1.1
Eye problems/disorders: Glaucoma 1.3 1.6 3.0 -1.3 0.7 1.4 1.4 1.7 0.5 0.6 1.5 1.2 0.1 1.2 0.9 1.3 1.3 0.7 0.4 -1.5 -1.4 -1.3 -1.6 -1.5 -1.2 -1.3 -1.5 -1.3 -1.2 -1.7
Medication: Blood pressure 0.9 1.8 8.0 -0.9 0.3 0.6 2.1 0.1 1.8 1.6 1.1 0.7 1.0 0.8 -0.1 0.9 2.1 0.5 2.8 -1.3 -1.6 -1.0 -1.5 -1.2 -0.9 -1.0 -1.4 -1.5 -1.9 -1.4
Pain type(s) experienced in last month: Hip pain 0.2 0.2 1.0 -0.5 0.0 -0.1 0.1 0.7 -0.5 0.3 -0.1 0.6 0.5 0.6 1.0 0.5 -0.1 -0.5 -0.5 -0.5 -0.1 -0.5 -0.4 -0.6 -0.6 -0.4 -0.2 -0.1 0.3 -0.4
Supplements: Fish oil (including cod liver oil) 0.8 1.0 2.5 0.6 -0.7 -1.6 -1.2 -1.3 -1.3 -0.6 -1.6 -1.0 -0.6 -0.8 -0.2 -0.9 -1.3 -0.1 -1.4 0.7 1.2 0.7 1.0 0.7 0.8 0.6 0.7 1.1 1.4 0.7
High cholesterol (Self-reported) 4.2 7.4 16.6 3.4 -3.6 -3.2 -1.5 -2.3 0.3 -2.8 -2.8 -3.3 -4.1 -3.4 -2.4 -3.2 0.6 1.6 3.4 2.7 2.0 3.4 1.9 2.7 3.4 3.4 2.7 2.3 0.8 1.7
Medication: Bendroflumethiazide 1.0 1.6 11.1 -0.4 0.2 -1.0 1.8 -0.6 2.4 1.9 0.7 0.2 -0.2 0.1 0.1 0.3 2.4 -0.4 3.3 -0.8 -1.3 -0.3 -1.2 -0.7 -0.3 -0.3 -0.8 -1.1 -1.8 -1.1
Medication: Paracetamol 1.1 1.7 4.7 1.6 -1.8 -2.2 -1.0 -1.8 -0.7 -1.9 -1.7 -1.4 -1.9 -1.4 0.1 -1.4 -0.3 0.0 0.7 0.9 1.3 1.5 0.7 0.8 1.4 1.4 1.2 1.4 1.2 0.2
Medication: Lisinopril 5.9 7.6 12.5 -2.9 2.6 2.5 3.3 2.6 2.9 3.5 3.1 2.9 2.4 2.7 2.3 2.9 2.2 -1.2 0.6 -3.1 -2.9 -2.9 -3.0 -3.1 -2.9 -3.0 -3.1 -2.8 -2.4 -3.1
Medication: Atorvastatin 0.2 0.2 1.1 0.2 -0.1 0.6 0.1 -0.3 0.0 0.3 -0.2 -0.3 -0.9 -0.4 1.1 -0.2 0.1 -1.0 0.6 -0.1 0.5 0.2 0.1 -0.2 0.2 0.2 0.2 0.6 0.8 -0.4
Illnesses of father: High blood pressure 0.4 0.5 1.3 -0.5 0.4 -0.1 0.9 0.1 1.1 0.1 0.7 0.8 -0.4 0.7 -0.4 0.7 0.8 0.2 1.1 -0.7 -0.9 -0.7 -0.8 -0.7 -0.7 -0.7 -0.8 -0.9 -1.0 -0.7
Alcohol drinker status: Never 0.4 0.5 1.3 -0.8 0.7 -0.4 1.0 0.2 -0.2 0.6 0.5 0.5 1.1 0.5 0.1 0.7 0.7 -1.0 0.2 -0.7 -0.8 -0.7 -0.7 -0.6 -0.7 -0.7 -0.8 -0.8 -0.8 -0.6
Ever smoked 1.3 2.4 4.6 -1.9 1.8 1.0 1.5 0.5 1.5 2.2 1.8 2.0 0.3 1.6 1.1 1.6 1.0 1.2 0.3 -1.7 -1.6 -1.8 -1.5 -1.6 -1.7 -1.9 -1.9 -1.7 -1.3 -1.5
Basal metabolic rate 0.0 0.3 3.3 0.1 -0.2 -0.7 -0.0 -0.5 -0.6 0.1 0.1 -0.3 -0.3 0.0 0.8 -0.1 0.3 1.0 -1.8 -0.2 0.1 0.0 -0.2 -0.3 0.0 -0.0 -0.1 0.2 0.3 -0.6
Leg fat percentage (left) 0.2 0.9 2.4 1.3 -1.1 -0.4 -0.6 -1.5 0.1 -0.8 -0.8 -1.2 -1.1 -1.3 -0.4 -1.1 -0.1 0.7 0.4 0.9 1.1 1.2 0.8 0.9 1.1 1.2 1.1 1.1 0.9 0.5
Arm fat-free mass (left) 0.0 0.2 2.4 0.0 -0.1 -1.0 0.2 -0.2 -0.4 0.5 0.3 -0.2 -0.3 0.1 0.8 -0.0 0.3 0.9 -1.5 -0.3 0.1 -0.0 -0.3 -0.4 -0.0 -0.1 -0.1 0.1 0.2 -0.7
Number of operations (self-reported) 0.9 1.4 3.8 1.1 -1.1 -0.8 -1.3 0.8 -0.6 -2.0 -0.8 -1.3 -0.5 -1.3 0.4 -1.4 -1.5 0.2 -0.8 1.0 1.7 1.2 1.2 0.9 1.3 1.1 1.1 1.7 1.9 0.5
Average weekly beer plus cider intake 0.7 1.0 2.3 1.1 -1.0 -1.1 -0.5 -1.5 -0.9 -1.5 -1.5 -0.9 -1.2 -1.0 -0.8 -1.0 -0.6 -0.8 0.2 1.0 0.9 1.0 0.9 1.0 0.9 1.0 1.0 0.9 0.7 0.9
Irritability 0.2 0.3 1.3 0.4 -0.5 0.1 -0.2 -1.0 -0.5 0.9 -1.1 -0.3 -1.2 -0.5 -0.8 -0.5 -0.2 -0.9 0.6 0.4 0.2 0.4 0.4 0.5 0.4 0.4 0.4 0.1 -0.0 0.5
Risk taking 0.2 0.3 1.5 -0.2 -0.1 -0.2 -0.2 0.3 -1.1 0.3 -0.2 0.3 0.4 0.2 -1.2 0.1 -0.8 0.7 -1.0 0.3 0.0 -0.1 0.5 0.4 -0.2 -0.2 0.1 -0.2 0.1 0.8
Ever had prostate specific antigen (PSA) test 1.4 1.6 10.4 0.0 -0.0 -0.7 -1.7 -1.2 -1.9 0.0 -1.1 -0.2 -0.5 -0.2 1.2 -0.3 -2.9 -0.4 -3.2 0.4 1.6 0.1 1.1 0.2 0.1 0.1 0.7 1.4 2.4 0.7
Fractured/broken bones in last 5 years 0.4 0.5 2.5 0.2 0.2 0.4 -0.2 1.6 0.8 -1.1 0.8 -0.1 -0.4 -0.1 1.3 -0.2 -0.7 -0.7 -1.0 0.1 0.9 0.2 0.2 -0.1 0.2 0.3 0.4 1.0 1.3 -0.2
Age started oral contraceptive pill 0.5 0.6 3.0 0.4 -0.1 -1.7 -0.3 -0.6 -1.0 0.6 -1.0 -1.0 0.2 -0.6 -0.1 -0.5 -0.8 -1.2 -0.6 0.7 0.8 0.6 0.8 0.7 0.6 0.6 0.7 0.7 0.8 0.7
Diastolic blood pressure, automated reading 0.5 1.5 4.7 -0.9 0.7 0.4 2.2 1.0 0.5 1.4 0.8 0.8 -0.9 0.8 1.7 1.1 1.7 -1.0 0.8 -1.5 -1.0 -1.0 -1.7 -1.6 -1.0 -1.0 -1.2 -0.9 -0.8 -2.1
Ever depressed for a whole week 3.5 4.4 6.6 2.5 -2.6 -2.1 -1.5 -2.3 -1.2 -1.7 -2.2 -2.4 -2.5 -2.4 -1.5 -2.4 -0.7 2.4 0.6 2.2 2.1 2.5 2.0 2.2 2.5 2.4 2.3 2.2 1.6 1.7
Unable to work because of sickness or disability 0.1 0.2 1.9 -0.1 0.2 -0.9 0.1 0.5 0.5 -0.9 -0.4 -0.0 -0.1 0.1 0.1 0.1 0.3 -1.4 0.0 -0.1 -0.2 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 -0.3 -0.1
Commuting to job workplace: Cycle 1.5 1.8 11.8 -1.3 1.4 1.0 0.8 3.4 -0.3 0.4 1.9 1.0 1.1 1.0 1.8 1.2 -0.9 -2.5 -1.9 -1.0 -0.2 -1.2 -0.6 -1.1 -1.2 -1.2 -0.8 -0.3 0.6 -0.8
Myopia 0.8 1.2 4.6 1.4 -0.9 -1.1 -1.5 -1.1 -1.3 -0.5 -0.7 -0.9 -1.3 -0.7 -2.1 -0.8 -0.5 0.7 -0.9 1.3 0.7 1.0 1.1 1.4 0.9 1.1 1.2 0.7 0.4 1.6
Vascular/heart problems diagnosed by doctor 2.1 5.7 12.3 2.0 -1.3 -1.0 -3.5 -1.6 -3.2 -3.2 -2.3 -1.9 -0.7 -1.9 -1.8 -2.1 -3.3 1.1 -2.5 2.8 2.6 2.2 3.1 2.8 2.1 2.1 2.6 2.3 2.5 3.2
Cholesterol lowering medication 2.3 3.3 10.5 2.2 -2.5 -1.5 0.0 -1.9 0.7 -1.5 -1.8 -2.4 -2.4 -2.3 -2.0 -2.2 0.9 1.0 3.2 1.7 1.0 2.2 1.1 1.8 2.2 2.2 1.6 1.2 -0.0 1.1
Medication: Omeprazole (e.g. Zanprol) 0.1 0.1 1.2 0.0 -0.1 0.1 0.2 0.3 0.5 -1.1 -0.1 -0.0 0.0 -0.1 -0.5 -0.1 0.2 -1.0 0.5 -0.0 -0.1 0.1 -0.0 0.0 0.1 -0.0 -0.1 -0.1 -0.2 -0.1
Pain experienced in last month 0.1 0.2 1.7 -0.3 1.0 0.8 0.3 -0.4 -0.5 0.1 0.1 0.2 0.1 0.4 -0.1 0.5 -0.4 -0.8 -1.3 -0.1 -0.1 -0.5 -0.0 -0.2 -0.5 -0.3 -0.2 -0.2 0.1 0.2
Supplements: Calcium 0.1 0.1 1.5 -0.1 0.5 1.2 0.2 0.2 0.3 -1.2 0.2 0.3 -0.4 0.0 0.2 -0.0 0.1 -0.1 -0.3 -0.1 -0.1 -0.1 -0.0 -0.1 0.1 -0.1 -0.2 0.0 -0.1 -0.2
Basal cell carcinoma (self-reported) 1.1 1.3 6.7 -0.6 0.9 0.3 1.4 1.0 2.6 0.4 1.7 0.8 1.6 0.6 0.8 0.7 1.1 -0.8 1.7 -1.0 -1.1 -0.8 -1.1 -1.0 -0.8 -0.7 -0.9 -1.0 -1.1 -1.2
Heart attack/myocardial infarction (self-reported) 0.5 0.7 2.3 -0.8 0.7 0.8 1.5 -0.1 -0.2 0.6 0.4 1.0 -0.2 0.7 -0.1 1.0 0.7 -0.2 0.6 -0.9 -1.1 -1.0 -0.9 -0.9 -1.1 -0.9 -0.9 -1.1 -1.0 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 3.6 -0.3 0.5 -0.0 0.2 1.1 0.3 -0.3 0.8 0.2 1.3 0.2 1.9 0.2 0.2 -1.3 -0.3 -0.8 0.1 -0.4 -0.5 -0.9 -0.2 -0.6 -0.6 0.1 0.5 -1.3
Heart disease (siblings) 0.8 1.0 11.3 -0.7 0.9 1.6 0.8 0.7 1.5 1.1 0.7 0.6 -0.1 0.6 0.8 0.6 0.2 -3.4 -0.4 -0.7 -0.4 -0.7 -0.6 -0.7 -0.7 -0.8 -0.7 -0.5 -0.2 -0.7
Alcohol drinker status: Previous 0.2 0.2 1.3 -0.5 0.3 -0.2 0.2 0.1 -0.3 0.3 -0.2 0.3 0.6 0.4 -0.0 0.5 0.4 -1.1 0.4 -0.4 -0.6 -0.5 -0.5 -0.4 -0.5 -0.4 -0.5 -0.6 -0.6 -0.3
Pack years of smoking 1.9 2.7 4.7 -1.6 1.2 1.0 1.8 1.1 1.3 1.2 1.1 1.8 1.7 1.6 1.1 1.7 2.1 -0.5 1.3 -2.0 -2.0 -1.7 -2.2 -2.0 -1.7 -1.7 -1.9 -1.9 -1.9 -2.1
Impedance of whole body 1.9 9.8 14.6 3.6 -3.4 -1.6 -3.3 -3.3 -0.6 -3.3 -3.6 -3.6 -3.0 -3.6 -3.5 -3.7 -1.3 2.3 2.1 3.7 2.7 3.7 3.3 3.8 3.7 3.6 3.3 2.8 1.5 3.4
Leg fat mass (left) 0.2 0.8 2.0 1.1 -1.1 -0.5 -0.4 -1.4 0.0 -0.9 -0.9 -1.1 -1.3 -1.2 -0.0 -1.0 0.2 1.0 -0.1 0.7 0.9 1.1 0.5 0.6 1.0 1.0 0.9 1.0 0.8 0.2
Arm predicted mass (left) 0.0 0.2 2.2 0.2 -0.3 -1.1 0.1 -0.3 -0.6 0.4 0.2 -0.3 -0.6 -0.1 0.5 -0.2 0.1 0.8 -1.5 -0.1 0.2 0.1 -0.1 -0.2 0.1 0.1 0.0 0.3 0.4 -0.4