TWAS hub - C1orf63

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.094	0.039	0.0049	0.042	NA	0.012	NA	0.030	0.00042	NA	0.04	NA	0.0025
2	GTEx	Vagina	0.330	0.106	0.0034	0.005	NA	0.011	NA	-0.012	0.24000	NA	0.18	NA	0.7500

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
LDL Cholesterol	12.3	19.5	38.4	-6.2	0.7
Tinnitus: Yes, but not now, but have in the past	9.7	10.3	18.6	-4.3	1.4
Blood Platelet Count	6.0	69.6	136.9	11.7	-1.5
Hair/balding pattern: Pattern 4	4.5	10.8	18.2	4.3	-1.8
Hair/balding pattern: Pattern 2	4.1	5.2	8.6	-2.9	1.4
Breastfed as a baby	3.9	4.9	5.2	2.1	-2.3
Ever depressed for a whole week	3.5	4.3	6.9	-2.6	1.3
High cholesterol (Self-reported)	3.3	5.9	11.7	-3.4	-0.4
Number of incorrect matches in round	3.1	5.1	8.6	-2.9	1.2
Major Depression (MDD)	3.0	3.7	7.3	2.7	-0.2
Tense / ‘highly strung’	2.9	4.8	9.6	-3.1	-0.0
Medication: Lisinopril	2.9	3.8	6.2	2.5	1.1
Impedance of leg (right)	2.8	13.4	26.8	-5.2	-0.2
Mouth/teeth dental problems: Bleeding gums	2.7	3.4	4.4	-2.1	1.6
Average weekly champagne plus white wine intake	2.7	3.7	6.5	2.5	-1.0
Hearing difficulty/problems: Yes	2.5	3.8	7.4	2.7	0.5
Length of working week for main job	2.5	2.8	4.2	2.0	-1.2
Comparative body size at age 10	2.5	7.0	13.5	3.7	-0.7
Alzheimer’s Disease (in mother)	2.4	2.9	4.0	-2.0	-1.3
Impedance of leg (left)	2.4	11.5	22.8	-4.8	-0.4
Forced expiratory volume in 1-second (FEV1)	2.3	7.9	10.5	-3.2	2.3
Heel bone mineral density (BMD) T-score, automated (right)	2.2	5.0	9.9	3.1	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	7.0	9.7	-3.1	2.1
Forced vital capacity (FVC), Best measure	2.2	8.2	12.7	-3.6	1.9
Prostate Cancer	2.1	2.9	4.5	-2.1	-1.2
Past tobacco smoking	2.1	3.8	6.8	-2.6	-0.9
Forced vital capacity (FVC)	2.1	8.1	12.6	-3.5	1.9
Number of full sisters	2.1	2.6	3.6	1.9	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	2.1	4.3	6.4	-2.5	1.5
Smoking Status	2.0	4.8	6.8	2.6	1.7
Chronic bronchitis/emphysema (father)	2.0	2.3	4.5	-0.5	2.1
Had menopause	2.0	2.6	5.1	-2.3	-0.0
Smoking status: Previous	2.0	2.9	5.9	2.4	-0.1
Alzheimer’s Disease (including proxy)	1.9	2.8	3.4	-1.5	-1.9
HbA1C	1.9	2.2	2.9	-1.2	-1.7
Triglycerides	1.9	3.2	5.0	-2.2	1.1
Mouth/teeth dental problems: Dentures	1.9	3.3	6.6	2.6	-0.0
Birth weight	1.9	4.2	6.7	2.6	-1.3
Medication: Co-codamol	1.8	2.1	3.5	1.9	-0.8
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	2.7	-1.2	-1.6
Medication: Seretide 50 evohaler	1.8	2.0	4.1	0.1	-2.0
Heel T-Score	1.7	13.6	26.9	5.2	-0.6
Height	1.7	32.8	34.1	-5.6	5.8
Angina	1.7	2.3	4.3	2.1	0.4
Average weekly fortified wine intake	1.7	2.0	4.0	-2.0	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	1.7	3.9	7.8	2.8	0.2
Asthma	1.7	3.4	4.8	-1.4	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	1.7	1.9	2.1	-1.4	1.4
Angina (self-reported)	1.7	2.2	4.3	2.1	0.4
Commuting to job workplace: Public transport	1.7	2.0	3.8	-0.5	1.9
Ever smoked	1.7	3.0	3.8	2.0	1.5
Medication for hormone replacement therapy	1.6	1.8	3.4	-0.4	-1.8
Standing height	1.6	16.0	17.6	-4.2	3.8
Peak expiratory flow (PEF)	1.6	3.6	4.9	-1.5	2.2
Cholesterol lowering medication	1.6	2.4	4.5	-2.1	0.5
Diabetes (mother)	1.5	1.9	2.7	1.6	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	2.1	-1.0	1.5
Wears glasses or contact lenses	1.5	1.7	2.4	-1.0	-1.6
Financial situation satisfaction	1.5	1.9	3.6	-1.9	0.3
Hypothyroidism (self reported)	1.4	3.3	6.5	-2.5	-0.4
Hearing difficulty/problems with background noise	1.4	2.3	3.5	1.9	1.0
Respiratory disease	1.3	2.9	5.6	-0.4	-2.4
Multivitamins +/- minerals	1.3	1.6	3.2	-0.2	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.8	-1.7	-0.3
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	4.8	-2.2	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	2.6	-1.6	-0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.6	2.9	1.7	-0.5
Medication: Blood pressure	1.3	2.3	4.6	2.2	0.1
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.2	-1.8	-0.0
Asthma (self-reported)	1.3	2.6	3.7	-1.2	-1.9
Myopia	1.3	1.8	1.9	-1.4	-1.3
Impedance of whole body	1.3	6.4	11.9	-3.5	-1.0
Ovarian Cancer	1.2	1.6	2.8	-0.5	1.7
Chronotype (morning person)	1.2	2.8	5.5	2.3	0.3
Severe depression (siblings)	1.2	1.4	2.7	-1.6	-0.2
Pack years adult smoking proportion	1.2	1.8	1.9	1.4	-1.3
Lung cancer (father)	1.2	1.4	2.4	1.5	-0.7
Friendships satisfaction	1.2	1.4	2.0	1.4	-0.9
Qualifications: nursing, teaching	1.2	1.9	3.3	-0.7	1.8
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.6	1.6	-0.5
Verbal and Numeric Reasoning (VNR)	1.1	2.7	5.3	-2.3	0.4
Fasting Glucose	1.1	1.4	2.7	0.1	-1.7
Rheumatoid Arthritis	1.1	1.5	2.9	1.7	-0.2
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	1.8	1.4	-0.8
Vitamin and mineral supplements	1.1	1.5	3.1	0.2	-1.8
Pulse rate	1.1	1.9	3.7	1.9	0.1
Medication: Cholesterol lowering	1.1	1.7	2.0	-1.4	-1.2
Number of children fathered	1.1	1.2	2.1	-0.6	-1.5
Migraine (self-reported)	1.1	1.3	2.1	-1.5	0.7
Breast Cancer	1.0	2.4	4.7	-2.2	-0.4
Mean Putamen Volume	1.0	1.1	2.2	1.5	-0.4
Primary Biliary Cirrhosis	1.0	1.5	1.6	1.3	1.2
Schizophrenia (2014)	1.0	2.2	2.7	1.3	1.7
Townsend deprivation index at recruitment	1.0	1.4	1.5	1.2	1.1
Maternal smoking around birth	1.0	1.5	2.8	0.4	1.7
Alcohol usually taken with meals	1.0	1.6	3.1	1.8	0.3
Qualifications: None of the above	1.0	2.1	3.7	1.9	-0.7
Number of full brothers	1.0	1.2	2.0	-1.4	-0.6
Arm predicted mass (right)	1.0	5.2	10.2	-0.4	3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.2	-0.5	-1.5
Miserableness	1.0	1.7	1.9	1.4	-1.2
Medication: Paracetamol	1.0	1.5	2.4	-1.5	-0.8
Pack years of smoking	1.0	1.4	1.5	1.2	-1.2
Intelligence (Savage-Jansen 2018)	0.9	2.8	4.5	-2.1	1.1
Medication: Atenolol	0.9	1.1	1.2	1.1	1.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.8	-1.4	0.7
Illnesses of siblings	0.9	1.3	2.4	-0.3	-1.6
Hair/balding pattern: Pattern 3	0.9	1.4	2.7	0.0	-1.6
Medication: Lansoprazole	0.9	1.1	2.1	-0.2	-1.4
Ever highly irritable/argumentative for 2 days	0.9	1.0	1.9	-1.4	0.4
Arm fat-free mass (right)	0.9	4.8	9.2	-0.5	3.0
Wheeze or whistling in the chest in last year	0.9	1.7	3.3	-0.1	-1.8
Qualifications: College or University degree	0.9	2.8	5.0	-0.7	2.2
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.0	-0.5	-1.4
Arm fat-free mass (left)	0.9	4.4	8.7	-0.2	3.0
Age started oral contraceptive pill	0.9	1.1	1.8	-0.7	1.3
Commuting to job workplace: Cycle	0.9	1.1	1.7	1.3	0.7
Worry (Nagel 2018)	0.8	1.6	2.8	-1.7	-0.6
Medication: Levothyroxine sodium	0.8	1.3	1.6	-1.0	-1.3
Sitting height	0.8	5.7	8.9	-1.6	3.0
Allergy	0.8	1.8	2.6	1.0	1.6
Trunk fat-free mass	0.8	4.8	9.0	-0.7	3.0
Time employed in main current job	0.8	0.9	1.8	0.4	-1.3
Trunk predicted mass	0.8	4.7	8.9	-0.7	3.0
Loud music exposure frequency	0.8	0.9	1.3	-0.6	1.2
Knee pain experienced in last month	0.8	1.3	2.5	1.6	-0.2
Illnesses of father: Heart disease	0.8	1.2	1.9	-1.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	1.7	-1.3	1.3
Guilty feelings	0.8	1.2	1.3	-1.0	-1.1
Vascular/heart problems diagnosed by doctor	0.8	2.2	4.5	-2.1	0.0
Arm predicted mass (left)	0.8	3.8	7.5	-0.4	2.7
Coronary Artery Disease (CAD)	0.7	0.9	1.6	-0.4	-1.3
HDL Cholesterol	0.7	1.2	1.8	-0.8	-1.3
Type 2 Diabetes (T2D) (2018)	0.7	1.4	2.6	0.4	1.6
Supplements: Zinc	0.7	0.8	1.5	-0.3	-1.2
Diabetes (father)	0.7	0.8	1.1	-1.1	-0.7
Diabetes (self-reported)	0.7	1.1	2.2	-0.1	1.5
Medication: Simvastatin	0.7	1.1	2.1	-1.5	-0.1
Impedance of arm (left)	0.7	3.0	4.9	-2.2	-1.1
Pulse wave reflection index	0.7	0.8	0.9	-0.9	0.9
Medication: Paracetamol	0.7	1.2	2.2	-0.5	-1.5
Medication: Amlodipine	0.7	1.0	1.9	1.4	-0.1
Medication: Omeprazole	0.7	0.9	1.2	0.7	-1.1
Whole body fat-free mass	0.7	4.1	8.2	-0.1	2.9
Leg fat-free mass (right)	0.7	3.6	5.9	1.2	2.4
Ever had bowel cancer screening	0.7	0.8	1.6	1.3	0.2
Breast cancer (self-reported)	0.7	0.8	1.6	1.3	-0.2
Whole body water mass	0.7	3.8	7.6	0.0	2.8
Basal metabolic rate	0.7	4.0	8.0	-0.2	2.8
Pain experienced in last month	0.7	1.1	1.7	0.7	1.3
Lupus	0.6	0.8	1.6	0.3	1.2
Lung FVC	0.6	2.9	5.8	-2.4	-0.1
Leg fat-free mass (left)	0.6	3.4	6.6	0.6	2.6
Taking other prescription medications	0.6	0.9	1.3	-1.1	-0.8
High blood pressure	0.6	1.6	2.9	1.7	0.5
Leg predicted mass (left)	0.6	3.2	6.2	0.6	2.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.4	-1.2	0.0
Fluid intelligence score	0.6	1.3	2.4	-1.6	0.4
Impedance of arm (right)	0.6	2.7	3.5	-1.9	-1.4
Exposure to tobacco smoke at home	0.6	0.6	1.0	-1.0	-0.5
Leg fat percentage (right)	0.6	2.2	3.9	-2.0	0.8
Eye problems/disorders: Cataract	0.6	0.7	1.5	-1.2	-0.0
Leg predicted mass (right)	0.6	3.4	5.7	1.1	2.4
Alcohol drinker status: Never	0.6	0.8	0.8	0.9	-0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.3	1.1	0.5
Age at First Birth	0.5	0.7	0.9	-1.0	0.6
Neuroticism (2016)	0.5	0.7	1.3	0.3	-1.2
Blood Red Count	0.5	4.8	8.4	-2.9	-1.1
Lung FEV1/FVC ratio	0.5	2.3	4.6	0.3	2.1
Alcohol intake versus 10 years previously	0.5	0.8	1.4	-0.5	-1.2
Qualifications: A levels/AS levels or equivalent	0.5	1.1	2.2	-0.2	1.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	1.3	-0.3	-1.1
Medication for pain relief, constipation, heartburn	0.5	0.9	1.5	-0.5	1.2
Medication: Ibuprofen	0.5	0.6	1.0	-0.3	1.0
Leg fat mass (right)	0.5	2.1	2.4	-1.6	1.3
Suffer from ‘nerves’	0.5	0.9	1.6	-1.2	-0.4
Hypertension (Self-reported)	0.5	1.4	2.2	1.5	0.7
Diabetes diagnosed by doctor	0.5	0.8	1.3	0.5	1.2
Back pain experienced in last month	0.5	0.8	1.3	0.6	-1.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.2	1.1	-0.2
Medication: Blood pressure	0.5	0.9	1.0	1.0	0.9
Medication: Bendroflumethiazide	0.5	0.7	0.8	0.8	0.9
Average weekly beer plus cider intake	0.5	0.7	1.4	-1.2	-0.0
Leg fat mass (left)	0.5	1.8	1.9	-1.4	1.3
Schizophrenia (2018)	0.4	0.8	1.5	1.2	0.3
Crohns Disease (2012)	0.4	0.7	1.1	0.6	1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.1	-1.0	0.2
Fed-up feelings	0.4	0.7	0.9	-1.0	-0.7
Qualifications: CSEs or equivalent	0.4	0.5	1.0	0.2	-1.0
Hayfever, allergic rhinitis or eczema	0.4	0.8	0.8	-0.9	-0.9
Trunk fat mass	0.4	1.7	2.0	-1.4	1.2
Nervous feelings	0.4	0.7	1.3	-0.2	-1.2
Had other major operations	0.4	0.5	1.0	-0.3	1.0
Heart attack	0.4	0.5	0.9	0.9	0.4
Weight	0.4	2.1	3.9	-0.6	2.0
Father’s age at death	0.4	0.5	0.6	0.8	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.0	-0.6	-1.0
Prospective memory result	0.4	0.4	0.9	0.9	-0.1
Blood clot in the leg (DVT)	0.4	0.5	1.1	0.1	-1.0
Gout (self-reported)	0.4	0.6	0.8	-0.9	-0.6
High blood pressure (siblings)	0.4	0.6	1.0	-0.5	1.0
Comparative height size at age 10	0.4	2.3	4.6	0.0	2.1
Supplements: Vitamin C	0.4	0.4	0.8	0.1	0.9
Illnesses of siblings: Diabetes	0.4	0.4	0.5	-0.6	-0.7
Illnesses of father: High blood pressure	0.4	0.5	0.7	0.6	-0.8
Leg fat percentage (left)	0.4	1.4	2.4	-1.5	0.6
Ever had prostate specific antigen (PSA) test	0.4	0.4	0.8	-0.0	0.9
Schizophrenia vs Biploar Disorder	0.3	0.3	0.7	0.8	0.1
Blood White Count	0.3	2.3	2.4	-1.5	1.5
Waist Hip Ratio (WHR)	0.3	1.3	2.2	1.5	-0.7
Systolic Blood Pressure	0.3	1.4	2.8	1.7	0.3
Neuroticism	0.3	0.8	0.9	-1.0	0.9
Hand grip strength (left)	0.3	0.8	1.2	-1.1	-0.6
Age when periods started (menarche)	0.3	0.7	1.1	-0.5	1.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.3	-0.5	-0.6
High blood pressure (mother)	0.3	0.5	0.9	0.9	0.1
Neuroticism score	0.3	0.5	1.0	-1.0	0.0
Happiness	0.3	0.3	0.5	0.4	0.7
Noisy workplace	0.3	0.3	0.6	-0.8	-0.2
Illnesses of mother	0.3	0.3	0.6	-0.8	-0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	0.8	0.4	0.9
Medication: Allopurinol	0.3	0.4	0.8	-0.9	-0.2
Heart disease (mother)	0.3	0.3	0.5	-0.7	0.4
Whole body fat mass	0.3	1.3	1.4	-1.1	1.2
Pulse rate, automated reading	0.3	1.1	2.1	1.5	0.0
Alcohol intake frequency.	0.3	0.7	1.3	0.4	-1.1
Overall health rating	0.3	0.7	1.5	-1.2	0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.7	0.2	-0.8
Mood swings	0.3	0.5	0.7	0.9	0.5
Commuting to job workplace: Walk	0.3	0.3	0.5	0.7	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	0.7	-0.8	0.5
Mother’s age at death	0.3	0.4	0.5	0.6	0.7
Number of operations (self-reported)	0.3	0.4	0.7	-0.8	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.8	0.3	-0.9
Depression (Nagel 2018)	0.2	0.3	0.6	0.2	-0.8
Neuroticism (Nagel 2018)	0.2	0.4	0.6	-0.5	-0.7
Ulcerative Colitis (UC)	0.2	0.4	0.4	0.6	-0.7
Ulcerative Colitis	0.2	0.4	0.4	0.6	0.6
BMI	0.2	1.3	1.8	1.3	-0.9
Medication: Metformin	0.2	0.3	0.4	0.4	0.6
Trunk fat percentage	0.2	0.7	1.4	-1.2	0.3
Stomach or abdominal pain in last month	0.2	0.3	0.5	0.3	-0.7
Supplements: Glucosamine	0.2	0.2	0.4	0.6	-0.3
Body mass index (BMI)	0.2	0.9	1.7	1.3	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.4	0.6	0.4
Financial difficulties in last 2 years	0.2	0.3	0.4	0.4	-0.6
Mouth/teeth dental problems	0.2	0.4	0.7	0.2	-0.8
Number of live births	0.2	0.2	0.4	-0.1	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.4	0.3	0.6
Depression (self-reported)	0.2	0.2	0.4	-0.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.6	-0.4	0.8
Headache pain in last month	0.2	0.3	0.5	0.3	-0.7
Body fat percentage	0.2	0.8	1.4	-1.2	0.3
Shortness of breath walking on level ground	0.2	0.3	0.4	-0.4	-0.7
Eye problems/disorders: None of the above	0.2	0.2	0.4	0.6	0.4
Chest pain or discomfort	0.2	0.3	0.5	-0.7	0.2
Had major operations	0.2	0.3	0.4	-0.7	0.3
Age at last live birth	0.2	0.3	0.4	-0.4	-0.6
Family relationship satisfaction	0.2	0.3	0.5	-0.2	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.4	-0.1	-0.6
Loneliness, isolation	0.2	0.3	0.5	0.7	0.4
Osteoporosis (self-reported)	0.2	0.3	0.4	-0.4	-0.6
Medication: Aspirin	0.2	0.3	0.6	0.8	-0.2
Medication: Gliclazide	0.2	0.2	0.4	0.6	0.2
Number of self-reported non-cancer illnesses	0.2	0.3	0.5	-0.7	-0.0
Ever taken oral contraceptive pill	0.2	0.2	0.2	0.4	-0.4
Medication: Atorvastatin	0.2	0.2	0.3	-0.3	-0.5
Irritability	0.2	0.4	0.6	-0.3	0.8
Diastolic blood pressure, automated reading	0.2	0.7	0.9	0.7	0.9
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.5	0.1	-0.7
Supplements: Calcium	0.2	0.2	0.4	0.6	0.3
Basal cell carcinoma (self-reported)	0.2	0.3	0.5	0.7	0.1
Alcohol drinker status: Previous	0.2	0.2	0.3	0.3	-0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	0.5	0.7	0.4
Depressed Affect (Nagel 2018)	0.1	0.2	0.4	0.1	-0.7
Alzheimer’s Disease (in father)	0.1	0.1	0.3	0.2	-0.5
Crohns Disease (2017)	0.1	0.2	0.3	0.5	0.4
Body Mass Index (BMI) (2010)	0.1	0.1	0.1	-0.2	0.3
Blood Eosinophil Count	0.1	0.7	1.3	-1.1	-0.4
Allergy or Eczema	0.1	0.2	0.3	-0.3	-0.6
Hair Pigment	0.1	1.6	2.2	1.5	-1.0
Number of treatments/medications taken	0.1	0.2	0.2	0.5	0.3
Relative age of first facial hair	0.1	0.1	0.2	-0.2	-0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	-0.0	0.6
Systolic blood pressure, automated reading	0.1	0.2	0.5	0.0	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.1	-0.4	0.3
Relative age voice broke	0.1	0.2	0.3	-0.0	-0.6
Serious illness, injury or assault to yourself	0.1	0.1	0.3	-0.1	0.5
Pain all over the body in last month	0.1	0.1	0.3	0.5	0.2
Medication: Ramipril	0.1	0.2	0.2	0.4	0.4
Arm fat percentage (right)	0.1	0.2	0.3	0.6	-0.4
Hip circumference	0.1	0.5	0.6	-0.8	0.6
Falls in the last year	0.1	0.2	0.2	-0.5	-0.4
Arm fat mass (right)	0.1	0.3	0.5	0.3	0.7
Birth weight of first child	0.1	0.1	0.2	-0.1	-0.5
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	-0.1	0.7
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.3	0.6	-0.1
Exposure to tobacco smoke outside home	0.1	0.1	0.2	0.5	-0.0
Pulse wave peak to peak time	0.1	0.1	0.2	-0.4	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.1	-0.3	-0.3
Neck or shoulder pain in last month	0.1	0.2	0.2	-0.5	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.3	-0.2	0.5
Leg pain on walking	0.1	0.2	0.3	0.5	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.2	-0.4	0.4
Medication: Aspirin	0.1	0.1	0.1	0.4	-0.1
Long-standing illness, disability or infirmity	0.1	0.2	0.3	0.6	0.3
Medication for cholesterol	0.1	0.2	0.4	0.6	-0.0
Mineral and other dietary supplements	0.1	0.1	0.1	-0.3	0.2
Osteoarthritis (self-reported)	0.1	0.2	0.3	0.2	-0.6
Smoking status: Current	0.1	0.1	0.2	0.0	0.4
Arm fat mass (left)	0.1	0.4	0.6	0.3	0.8
Hearing aid user	0.1	0.1	0.1	0.2	0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	0.2	-0.4
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.2	-0.4	-0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.1	-0.2	0.3
Heart disease (siblings)	0.1	0.2	0.3	0.5	-0.2
Bipolar Disorder (2018)	0.0	0.1	0.1	-0.3	0.0
Irritable Bowel Disease (IBD)	0.0	0.1	0.2	0.4	-0.0
Reaction Time	0.0	0.1	0.1	0.1	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	-0.0	-0.1
Cardiovascular Disease	0.0	0.0	0.0	-0.1	-0.2
Tanning	0.0	0.0	0.0	0.2	-0.1
Average weekly spirits intake	0.0	0.0	0.0	-0.1	-0.2
Sensitivity / hurt feelings	0.0	0.1	0.1	0.3	0.3
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.1	-0.2	0.0
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.1	-0.1
Hand grip strength (right)	0.0	0.1	0.2	-0.5	0.2
Current tobacco smoking	0.0	0.0	0.0	-0.2	0.1
Waist circumference	0.0	0.1	0.2	0.5	-0.1
Worrier / anxious feelings	0.0	0.1	0.1	0.3	-0.0
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	0.1	0.2
Glaucoma (self-reported)	0.0	0.1	0.1	-0.3	0.2
Worry too long after embarrassment	0.0	0.0	0.1	0.1	0.3
Age at first live birth	0.0	0.1	0.1	0.2	-0.3
Health satisfaction	0.0	0.0	0.1	0.3	-0.0
Mean time to correctly identify matches	0.0	0.0	0.0	-0.0	0.1
Arm fat percentage (left)	0.0	0.1	0.1	0.4	-0.2
Average weekly red wine intake	0.0	0.1	0.1	0.3	-0.0
Illnesses of father: None of the above (group 1)	0.0	0.0	0.1	0.3	0.1
Risk taking	0.0	0.0	0.0	-0.0	0.0
Unable to work because of sickness or disability	0.0	0.0	0.0	0.1	0.2

Hub : Genes

C1orf63

Models

Trait associations