[Hub]/) : Traits : Impedance of leg (left) : ← →

chr9:94,363,366-97,136,378

Best TWAS P=1.83e-12 · Best GWAS P=7.55e-13 conditioned to 0.000152

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	OGN	0.04	0.04	lasso	4	0.04	2.3e-05	-4.852	-5.6	1.7e-08	-0.01	0.09	0.90	FALSE
2	GTEx	Brain Caudate basal ganglia	PHF2	0.42	0.00	enet	33	0.04	2.4e-02	-0.007	-5.1	2.8e-07	-0.25	0.10	0.06	FALSE
3	GTEx	Brain Cerebellar Hemisphere	IPPK	0.17	0.22	lasso	13	0.16	6.8e-05	-5.669	-5.3	1.5e-07	0.10	0.17	0.76	FALSE
4	GTEx	Brain Cerebellum	ZNF484	0.21	0.01	lasso	9	0.01	1.7e-01	5.926	5.5	3.2e-08	-0.03	0.09	0.24	FALSE
5	GTEx	Brain Cerebellum	BICD2	0.23	0.06	enet	21	0.17	8.5e-06	5.926	5.5	4.4e-08	0.09	0.07	0.31	FALSE
6	GTEx	Cells Transformed fibroblasts	OGN	0.03	0.03	lasso	2	0.01	3.2e-02	-6.084	-6.1	1.2e-09	0.05	0.07	0.89	FALSE
7	GTEx	Esophagus Mucosa	CENPP	0.09	0.01	lasso	5	0.02	2.1e-02	3.963	-5.3	1.2e-07	-0.02	0.19	0.61	FALSE
8	GTEx	Esophagus Muscularis	BICD2	0.09	0.02	enet	26	0.07	5.0e-05	4.409	5.4	6.0e-08	0.11	0.08	0.63	TRUE
9	GTEx	Heart Left Ventricle	ECM2	0.07	0.05	lasso	3	0.02	3.1e-02	6.003	6.1	1.2e-09	-0.01	0.09	0.68	FALSE
10	GTEx	Liver	ECM2	0.16	0.18	enet	8	0.18	7.4e-06	-6.172	6.0	1.9e-09	-0.07	0.06	0.94	FALSE
11	GTEx	Nerve Tibial	OGN	0.08	0.14	lasso	9	0.12	6.3e-09	-5.586	-5.9	3.8e-09	0.09	0.10	0.90	FALSE
12	GTEx	Nerve Tibial	NOL8	0.10	0.02	enet	7	0.03	4.7e-03	-5.344	5.4	6.4e-08	-0.04	0.36	0.52	FALSE
13	GTEx	Pituitary	IPPK	0.16	0.07	lasso	4	0.07	8.5e-03	-5.541	-6.6	4.9e-11	0.10	0.07	0.67	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	CENPP	0.23	0.09	lasso	11	0.07	9.6e-05	5.571	-5.2	1.7e-07	-0.01	0.37	0.54	FALSE
15	GTEx	Skin Sun Exposed Lower leg	CENPP	0.20	0.06	lasso	9	0.14	2.9e-11	5.561	-5.9	4.2e-09	-0.02	0.39	0.61	FALSE
16	GTEx	Small Intestine Terminal Ileum	CENPP	0.29	0.11	enet	11	0.10	2.9e-03	-5.700	-6.4	1.5e-10	0.02	0.09	0.72	FALSE
17	GTEx	Spleen	NOL8	0.29	0.24	lasso	2	0.19	1.1e-05	-5.244	5.3	1.4e-07	-0.06	0.34	0.52	FALSE
18	GTEx	Testis	NOL8	0.19	0.24	lasso	11	0.23	1.3e-10	-4.920	5.1	3.0e-07	-0.09	0.29	0.71	FALSE
19	NTR	Blood	IPPK	0.02	0.01	bslmm	416	0.01	9.9e-06	-6.090	-5.8	8.8e-09	0.07	0.05	0.95	FALSE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CENPP	0.08	0.00	lasso	6	0.00	1.3e-01	-3.750	-5.6	2.5e-08	-0.04	0.04	0.34	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	CENPP	0.07	0.03	lasso	5	0.06	2.1e-11	5.561	-7.0	3.6e-12	0.02	0.06	0.94	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	OGN	0.02	0.02	lasso	1	0.02	2.7e-04	-5.557	-5.6	2.7e-08	0.11	0.04	0.94	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPP	0.21	0.04	enet	16	0.10	1.9e-06	5.571	-6.8	8.6e-12	0.11	0.08	0.75	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPP	0.06	0.02	blup	160	0.04	6.3e-05	5.571	-7.0	1.8e-12	0.03	0.07	0.87	TRUE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	OGN	0.02	0.01	blup	51	0.01	3.4e-02	-5.202	-6.0	1.4e-09	0.06	0.01	0.82	FALSE
26	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	OGN	0.07	0.08	lasso	1	0.06	8.0e-04	-5.375	-5.4	7.7e-08	0.05	0.04	0.85	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	ECM2	0.10	0.04	lasso	2	0.04	4.2e-05	5.630	5.2	2.2e-07	-0.04	0.12	0.53	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	OGN	0.07	0.12	blup	52	0.14	1.2e-15	-5.375	-5.8	5.7e-09	0.05	0.03	0.97	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	OMD	0.04	0.06	lasso	3	0.05	1.1e-06	-5.375	-5.4	7.7e-08	0.05	0.11	0.89	FALSE
30	The Cancer Genome Atlas	Lung Adenocarcinoma	PHF2	0.07	0.03	blup	104	0.05	1.9e-06	-4.264	-5.2	2.2e-07	-0.05	0.83	0.01	FALSE
31	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CENPP	0.06	0.04	blup	160	0.05	5.6e-06	5.571	-6.6	3.1e-11	0.02	0.11	0.87	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OGN	0.02	0.02	blup	52	0.02	2.8e-03	4.940	-5.9	4.9e-09	0.09	0.03	0.90	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CENPP	0.10	0.01	blup	161	0.04	6.3e-04	0.545	-5.9	4.2e-09	-0.01	0.10	0.67	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	OGN	0.05	0.02	blup	52	0.03	2.4e-02	4.940	-5.8	6.3e-09	0.09	0.04	0.52	FALSE
35	The Cancer Genome Atlas	Soft Tissue Sarcoma	PHF2	0.05	0.03	blup	103	0.04	3.5e-03	5.982	-6.9	5.3e-12	-0.56	0.06	0.34	TRUE
36	The Cancer Genome Atlas	Stomach Adenocarcinoma	CENPP	0.14	0.03	blup	160	0.04	6.7e-04	5.561	-5.6	2.3e-08	-0.03	0.17	0.62	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	CENPP	0.22	0.15	blup	158	0.19	3.3e-18	-3.528	-5.4	5.1e-08	-0.02	0.92	0.08	FALSE
38	The Cancer Genome Atlas	Thyroid Carcinoma	IPPK	0.03	0.04	blup	50	0.04	6.7e-05	5.603	-6.2	5.6e-10	0.07	0.02	0.98	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	NOL8	0.02	0.01	blup	38	0.02	7.3e-03	-5.208	5.7	1.6e-08	-0.09	0.02	0.74	FALSE