TWAS hub - MAPKBP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1000	0.0250	3.0e-10	0.063	0.101	0.105	0.101	0.098	4.1e-08	2.7e-12	9.6e-13	2.6e-12	5.4e-12
2	GTEx	Artery Aorta	0.1240	0.0490	1.5e-03	0.000	NA	-0.004	NA	-0.004	3.2e-01	NA	6.4e-01	NA	6.2e-01
3	GTEx	Artery Tibial	0.0666	0.0321	3.0e-03	0.008	NA	-0.003	NA	-0.001	7.4e-02	NA	6.4e-01	NA	4.3e-01
4	GTEx	Brain Cerebellum	0.2320	0.0770	6.9e-04	0.090	NA	0.093	NA	0.120	1.3e-03	NA	1.1e-03	NA	2.2e-04
5	GTEx	Brain Cortex	0.2900	0.1070	1.6e-03	-0.003	NA	0.041	NA	0.028	4.1e-01	NA	2.7e-02	NA	5.6e-02
6	GTEx	Nerve Tibial	0.0871	0.0341	1.5e-03	0.048	NA	0.061	NA	0.078	2.7e-04	NA	4.1e-05	NA	3.5e-06
7	GTEx	Pituitary	0.2160	0.0810	3.1e-03	0.062	NA	-0.009	NA	0.068	1.2e-02	NA	6.3e-01	NA	8.6e-03
8	GTEx	Testis	0.2020	0.0750	8.5e-04	0.015	NA	0.042	NA	0.030	6.6e-02	NA	5.8e-03	NA	1.8e-02
9	METSIM	Adipose	0.0804	0.0268	2.3e-06	0.027	0.022	0.011	0.021	0.025	6.1e-05	2.7e-04	6.8e-03	3.7e-04	1.1e-04
10	YFS	Blood	0.0615	0.0141	0.0e+00	0.064	0.077	0.074	0.079	0.081	4.6e-20	4.7e-24	5.3e-23	1.6e-24	4.7e-25

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Lung FEV1/FVC ratio	19.8	100.4	125.4	-11.1	-11.0	-11.2	-9.6	-9.5	-11.1	-8.5	-8.6	-10.0	9.2
Diastolic blood pressure, automated reading	12.7	39.4	53.7	-7.3	-6.2	-6.5	-7.3	-7.0	-6.5	-5.0	-5.2	-6.0	5.3
Alcohol drinker status: Never	9.5	11.4	15.6	-3.0	-3.7	-3.1	-3.0	-4.0	-2.9	-4.0	-3.0	-3.6	3.3
Number of full brothers	8.6	10.8	17.6	-2.6	-2.4	-3.4	-3.1	-3.8	-2.1	-3.4	-3.1	-4.2	4.2
Medication: Gliclazide	8.4	9.5	14.0	-2.8	-3.2	-2.5	-3.7	-3.5	-2.9	-3.5	-2.2	-3.4	2.7
Triglycerides	8.3	13.5	15.9	-3.2	-3.7	-4.0	-3.8	-3.9	-3.7	-3.9	-3.1	-3.7	3.7
Diabetes diagnosed by doctor	7.2	11.8	22.3	-3.8	-4.7	-3.6	-4.0	-3.1	-4.2	-2.6	-1.4	-3.0	2.6
Waist Hip Ratio (WHR)	7.0	31.3	53.3	-5.7	-6.4	-5.5	-7.3	-5.8	-6.3	-5.0	-3.3	-5.2	4.5
Type 2 Diabetes (T2D) (2018)	6.9	13.0	25.7	-4.1	-5.1	-3.8	-4.1	-3.0	-4.8	-2.9	-0.7	-3.0	2.5
HDL Cholesterol	6.8	11.4	19.1	2.6	3.8	4.1	3.6	3.9	4.4	2.9	2.6	2.9	-2.3
Qualifications: NVQ or HND or HNC or equivalent	6.7	8.0	16.7	-3.4	-4.1	-1.6	-3.6	-2.8	-3.8	-1.9	-1.4	-2.2	1.9
Medication: Metformin	6.5	9.2	16.7	-3.2	-4.1	-3.3	-3.7	-3.0	-4.1	-2.1	-1.2	-2.3	1.8
Diabetes (father)	5.9	7.3	11.3	-3.0	-2.8	-2.7	-2.6	-2.6	-2.4	-1.8	-2.4	-3.1	3.4
Diabetes (self-reported)	5.5	8.5	17.5	-3.5	-4.2	-3.2	-3.4	-2.5	-3.7	-2.1	-1.1	-2.1	1.9
Systolic Blood Pressure	5.1	25.3	60.2	-5.5	-4.8	-5.9	-7.8	-6.3	-5.1	-2.9	-3.5	-3.5	2.5
Medication: Paracetamol	5.0	7.7	10.8	-3.2	-3.3	-2.5	-3.1	-2.4	-2.9	-3.0	-1.6	-2.8	2.6
Number of treatments/medications taken	4.5	8.1	12.6	-3.0	-2.9	-2.8	-3.6	-2.7	-2.6	-2.7	-1.7	-3.2	2.9
Medication for pain relief, constipation, heartburn	4.4	7.5	11.3	3.4	2.7	1.9	2.8	2.3	2.5	3.1	2.5	3.0	-2.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.3	5.0	11.2	-2.0	-2.1	-2.4	-2.3	-1.4	-2.0	-3.3	-2.3	-2.1	1.9
Diabetes (mother)	4.2	5.4	9.5	-1.7	-3.1	-2.0	-2.7	-2.1	-2.9	-2.0	-1.9	-2.3	2.1
Medication: Paracetamol	4.2	6.9	11.0	-2.9	-3.3	-2.5	-3.0	-2.4	-3.1	-2.5	-1.5	-2.4	2.1
Father’s age at death	4.0	5.3	10.4	2.1	2.8	2.1	3.2	2.4	2.3	1.1	1.8	2.5	-2.0
Systolic blood pressure, automated reading	3.8	11.1	20.5	-3.6	-2.7	-4.3	-4.5	-4.2	-3.0	-2.2	-3.3	-2.7	1.8
Hearing difficulty/problems with background noise	3.8	6.1	11.9	2.7	2.2	1.6	1.8	2.5	2.0	2.6	2.3	2.9	-3.4
Cardiovascular Disease	3.6	11.9	23.0	-3.4	-4.3	-4.0	-4.8	-3.9	-3.8	-2.0	-1.7	-3.0	2.2
High blood pressure (mother)	3.6	5.0	11.9	-2.0	-3.1	-2.6	-2.7	-2.2	-3.4	-0.8	-1.2	-1.7	0.8
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	8.4	2.1	1.7	2.3	1.9	1.6	1.5	2.9	2.0	2.1	-1.9
Supplements: Zinc	3.4	3.7	7.2	-2.0	-2.7	-1.9	-1.7	-1.9	-2.1	-1.1	-2.1	-1.9	1.5
Bilateral oophorectomy (both ovaries removed)	3.4	3.9	7.2	-2.5	-2.6	-1.6	-1.9	-1.8	-2.7	-1.7	-1.3	-1.5	1.4
Medication: Levothyroxine sodium	3.4	5.8	9.1	-2.4	-2.8	-2.4	-2.3	-2.0	-2.1	-2.2	-1.5	-3.0	2.9
Wears glasses or contact lenses	3.4	3.9	9.7	2.7	2.6	1.8	2.0	0.8	3.1	1.6	0.7	1.4	-1.6
Hypothyroidism (self reported)	3.3	7.6	12.0	-2.7	-2.1	-3.0	-2.8	-2.9	-2.0	-2.3	-2.6	-3.4	3.5
Mother’s age at death	3.3	4.2	8.1	2.1	2.5	2.0	2.8	1.8	2.8	1.3	-0.1	1.9	-1.8
Eye problems/disorders: Diabetes related eye disease	3.2	3.5	7.2	-1.8	-2.1	-0.8	-1.6	-1.1	-1.6	-2.7	-2.1	-1.9	2.2
Hypothyroidism/myxoedema (self-reported)	3.2	6.2	9.5	-2.3	-2.4	-2.5	-2.9	-2.3	-2.1	-2.1	-1.6	-3.1	3.0
High blood pressure	3.1	8.8	16.0	-2.8	-3.5	-3.8	-4.0	-3.2	-3.3	-1.7	-2.1	-2.6	1.5
Headache pain in last month	3.1	5.3	10.2	-2.8	-2.3	-2.8	-1.7	-2.2	-3.2	-1.3	-2.1	-1.9	2.0
Reaction Time	2.9	5.5	10.6	-2.3	-3.1	-1.6	-3.2	-2.6	-3.3	-1.6	-1.3	-1.9	1.5
Hearing difficulty/problems: Yes	2.9	4.5	7.1	2.6	1.6	1.4	1.8	2.2	1.9	1.9	2.5	2.3	-2.7
Medication: Cholesterol lowering	2.9	4.5	9.9	-1.8	-1.6	-1.5	-2.0	-2.0	-0.9	-2.6	-1.5	-3.0	3.1
Average weekly champagne plus white wine intake	2.9	4.0	6.5	1.4	1.3	1.8	2.4	2.0	1.2	2.5	2.3	2.2	-2.3
Fractured/broken bones in last 5 years	2.9	3.7	6.8	-1.5	-1.1	-1.9	-1.7	-1.6	-1.2	-2.0	-2.6	-2.4	2.5
Neuroticism (2016)	2.8	4.1	8.1	-1.7	-2.7	-1.6	-2.0	-1.8	-2.8	-2.1	-1.5	-1.8	1.7
Impedance of leg (right)	2.8	13.4	36.0	-4.0	-4.3	-1.9	-6.0	-3.4	-4.2	-2.6	-0.7	-3.6	3.3
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	6.7	2.0	2.2	1.8	2.2	2.4	2.6	0.8	1.7	1.2	-0.6
Alcohol intake frequency.	2.7	6.4	9.2	-1.6	-3.0	-2.9	-2.6	-2.6	-2.6	-2.5	-1.5	-2.7	2.7
Hypertension (Self-reported)	2.7	7.4	14.1	-2.5	-3.5	-3.5	-3.8	-2.9	-3.2	-1.3	-1.6	-2.2	1.0
Severe depression (siblings)	2.5	2.8	7.1	2.7	0.9	1.4	1.6	1.1	1.1	2.1	0.2	2.0	-2.2
Had other major operations	2.5	3.0	6.0	1.7	1.8	1.8	1.3	1.5	1.8	1.3	2.4	2.0	-1.4
Financial difficulties in last 2 years	2.5	3.3	6.3	-1.6	-2.5	-1.3	-2.1	-1.9	-2.1	-1.8	-0.4	-1.8	2.0
Medication: Ramipril	2.5	3.3	8.7	-1.7	-2.9	-2.3	-2.0	-1.6	-2.9	-0.1	-0.1	-0.4	-0.2
Medication for cholesterol, blood pressure or diabetes	2.5	4.2	7.2	2.0	2.2	2.0	2.4	1.9	1.5	1.8	1.4	2.7	-2.2
Serious illness, injury or assault to yourself	2.4	2.9	5.3	-1.6	-2.3	-1.7	-1.7	-1.8	-1.6	-1.5	-0.9	-1.9	1.8
Alcohol usually taken with meals	2.4	3.9	7.9	1.4	2.8	2.3	2.8	1.5	2.8	1.5	1.3	1.3	-0.8
Average weekly red wine intake	2.4	3.5	8.4	2.1	2.3	2.9	2.2	1.6	1.9	1.1	1.8	1.3	-0.5
Vascular/heart problems diagnosed by doctor	2.4	6.5	13.4	2.5	3.0	3.5	3.7	2.8	2.8	1.2	1.3	2.0	-1.0
Hair/balding pattern: Pattern 4	2.3	5.6	8.5	2.6	2.8	2.9	2.3	2.3	2.6	1.3	1.7	2.3	-2.3
Age at last live birth	2.3	3.4	7.5	2.0	1.3	2.0	2.7	2.2	2.1	1.4	1.2	1.5	-1.2
Major Depression (MDD)	2.2	2.7	6.7	-1.1	-2.5	-1.4	-2.1	-1.5	-2.6	-1.2	-0.4	-1.1	1.0
Ulcerative Colitis	2.2	3.2	4.6	1.9	1.6	2.0	1.8	2.1	1.6	1.5	1.6	1.9	-1.8
Lung FVC	2.2	11.3	23.1	2.6	3.3	2.5	2.7	2.8	2.1	3.9	3.2	4.6	-4.8
Pack years adult smoking proportion	2.2	3.3	5.8	-2.1	-1.6	-2.4	-0.8	-2.0	-1.6	-1.4	-2.1	-1.9	1.9
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	4.7	-2.2	-1.8	-1.1	-1.5	-1.7	-1.6	-1.6	-1.8	-1.8	1.4
Number of full sisters	2.2	2.7	6.7	-1.4	-2.6	-1.8	-1.9	-2.0	-1.8	-0.8	-0.2	-1.2	1.3
Commuting to job workplace: Cycle	2.2	2.6	4.4	1.8	1.7	1.8	1.1	1.5	1.6	1.1	1.4	2.1	-1.8
Age when periods started (menarche)	2.1	5.0	8.5	-2.3	-2.8	-0.9	-2.9	-1.9	-2.9	-1.9	-2.2	-2.0	1.7
Commuting to job workplace: Walk	2.1	2.3	3.9	2.0	1.3	1.6	1.4	1.8	0.7	0.4	2.0	1.7	-1.6
Pack years of smoking	2.1	3.0	5.5	-1.8	-1.4	-2.3	-0.7	-2.0	-1.5	-1.3	-2.1	-1.9	1.8
Crohns Disease (2012)	2.0	3.3	6.6	1.6	1.6	0.9	2.5	2.0	1.9	2.6	1.1	1.8	-1.5
Multivitamins +/- minerals	2.0	2.6	7.2	-1.4	-1.2	-0.1	-0.5	-1.3	-0.6	-1.5	-2.4	-2.2	2.7
Medication: Amlodipine	2.0	2.8	5.9	-1.2	-1.7	-2.0	-2.3	-2.4	-1.9	-1.2	-1.0	-1.3	0.8
Medication: Ibuprofen	2.0	2.3	4.6	-1.7	-1.4	-0.6	-1.3	-1.1	-1.1	-2.1	-1.4	-1.9	1.9
Leg pain on walking	2.0	2.6	6.3	-1.4	-2.5	-1.3	-2.1	-1.2	-2.4	-0.9	0.0	-1.6	1.1
Breast cancer (self-reported)	2.0	2.4	5.8	2.2	2.3	1.7	1.1	1.4	2.4	0.2	0.1	1.0	-1.1
Osteoporosis (self-reported)	2.0	2.5	5.8	1.2	2.4	1.3	1.4	1.3	2.2	1.1	1.1	1.4	-1.7
Medication: Bendroflumethiazide	2.0	3.0	7.4	-2.1	-1.4	-2.3	-2.6	-2.7	-1.9	0.2	-0.9	-0.5	0.0
Ever had prostate specific antigen (PSA) test	2.0	2.3	5.8	-0.9	-0.6	0.8	-1.2	-0.9	-0.3	-2.1	-2.2	-2.1	2.4
Alzheimer’s Disease (in father)	1.9	2.0	5.0	0.6	1.1	2.2	0.5	1.4	0.7	1.0	1.1	2.1	-2.1
Bipolar Disorder (2011)	1.8	1.8	5.3	-1.1	-1.7	-1.2	-1.3	-0.5	-1.5	-1.4	-2.3	-0.8	0.4
Blood Red Count	1.8	17.7	28.5	-3.9	-5.0	-4.5	-4.4	-3.5	-5.3	-2.9	-4.1	-4.3	3.6
Impedance of leg (left)	1.8	8.8	27.0	-3.0	-3.8	-0.9	-5.2	-2.5	-3.5	-1.8	0.0	-2.8	2.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.7	13.7	-3.4	-2.6	-2.4	-2.2	-1.4	-3.7	-1.9	-2.1	-1.6	1.3
High blood pressure (siblings)	1.8	2.5	5.5	-0.8	-0.3	-2.3	-1.1	-2.0	-0.8	-1.7	-2.3	-1.9	1.4
Medication: Atorvastatin	1.8	2.2	4.4	-1.4	-1.5	-1.2	-1.1	-1.2	-1.3	-1.7	-1.1	-1.9	2.1
Overall health rating	1.7	3.7	7.5	-2.1	-2.5	-2.6	-2.0	-2.1	-2.7	-1.4	-0.5	-1.0	0.7
Illness, injury, bereavement, stress in last 2 years	1.7	2.0	4.6	1.0	2.1	1.5	1.6	1.2	1.9	1.2	-0.1	1.4	-1.1
Age at First Birth	1.6	2.3	5.6	1.7	2.2	1.5	1.5	1.3	2.4	0.4	1.6	0.5	-0.0
Fasting Glucose	1.6	1.9	3.8	-1.7	-1.3	-2.0	-1.2	-1.2	-1.2	-1.1	-1.2	-1.5	1.4
Vitamin and mineral supplements	1.6	2.2	5.2	1.8	1.2	0.1	0.7	1.2	0.8	1.3	2.3	1.7	-2.1
Current tobacco smoking	1.6	2.7	3.8	-1.4	-1.8	-1.9	-1.5	-2.0	-1.4	-1.4	-1.3	-1.8	1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.6	6.7	1.9	2.3	1.1	1.5	1.8	2.6	1.9	1.6	1.8	-2.0
Mouth/teeth dental problems: Dentures	1.6	2.7	4.1	-1.7	-1.6	-1.6	-2.0	-1.9	-1.5	-1.6	-1.1	-1.7	1.4
Glaucoma (self-reported)	1.6	1.9	3.0	1.6	1.6	0.9	1.7	1.6	1.6	1.7	0.5	1.2	-0.8
Mineral and other dietary supplements	1.6	2.2	4.4	1.4	1.6	-0.2	2.1	0.6	1.6	1.6	1.6	1.7	-1.4
Smoking status: Current	1.6	2.6	3.7	-1.5	-1.7	-1.8	-1.4	-1.9	-1.4	-1.4	-1.4	-1.7	1.7
Ever used hormone-replacement therapy (HRT)	1.5	1.9	4.6	-2.2	-1.9	-1.4	-1.2	-1.2	-1.8	-0.6	-0.4	-0.9	1.1
Ever had hysterectomy (womb removed)	1.5	1.6	4.5	-0.9	-1.8	-0.3	-1.8	-1.7	-2.1	-1.0	0.3	-0.6	0.6
Illnesses of siblings: Diabetes	1.5	1.8	2.9	-1.2	-1.3	-1.2	-1.6	-1.1	-1.7	-0.9	-1.7	-1.4	1.2
Pulse wave reflection index	1.4	1.7	4.7	-1.0	-0.7	-0.8	-0.5	-1.0	-0.5	-1.4	-1.6	-2.0	2.2
Number of self-reported non-cancer illnesses	1.4	2.4	7.1	-1.6	-1.7	-1.6	-2.7	-2.1	-1.9	-0.5	-0.2	-0.9	0.3
Guilty feelings	1.4	2.1	4.5	-1.2	-2.1	-1.7	-1.5	-0.8	-2.1	-1.1	-0.9	-1.0	1.3
High cholesterol (Self-reported)	1.4	2.5	4.5	-1.0	-1.8	-1.7	-1.7	-1.6	-1.2	-1.1	-1.4	-2.1	1.9
Ever smoked	1.4	2.5	5.6	2.4	1.2	0.8	1.0	0.6	0.8	2.0	2.0	2.0	-1.9
Impedance of whole body	1.4	7.0	22.1	-2.7	-3.2	-0.8	-4.7	-2.4	-3.0	-1.8	-0.2	-2.6	2.4
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	3.9	-1.4	-1.6	-0.5	-1.8	-1.1	-2.0	-0.2	-0.8	-0.3	0.1
Long-standing illness, disability or infirmity	1.3	2.0	6.1	-1.1	-2.2	-1.1	-1.9	-0.4	-2.5	0.8	0.6	0.7	-1.2
Waist circumference	1.2	4.2	9.4	-1.4	-1.6	-3.1	-1.0	-2.0	-1.7	-1.7	-3.0	-2.2	1.9
Ever highly irritable/argumentative for 2 days	1.2	1.5	3.4	-1.1	-1.8	-1.1	-0.3	-0.6	-1.0	-1.2	-1.0	-1.7	1.6
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	6.2	0.8	0.9	2.5	1.6	1.7	0.6	0.8	1.7	1.4	-0.7
Supplements: Fish oil (including cod liver oil)	1.2	1.6	2.6	-1.0	-1.5	0.5	-1.6	-0.5	-1.4	-1.4	-1.3	-1.5	1.5
Rheumatoid Arthritis	1.1	1.6	3.9	1.1	0.6	1.7	0.0	1.1	0.0	2.0	1.8	1.1	-1.3
Chronotype (morning person)	1.1	2.7	7.2	1.7	1.3	0.9	1.4	1.0	0.9	1.7	1.0	2.5	-2.7
Frequency of depressed mood in last 2 weeks	1.1	1.6	4.4	-0.7	-1.9	-1.2	-0.9	-0.8	-2.1	-1.4	-0.5	-1.1	1.0
Townsend deprivation index at recruitment	1.1	1.5	4.6	-0.1	-2.1	-2.0	-1.1	-0.7	-1.9	0.0	0.8	0.5	-0.7
Impedance of arm (right)	1.1	5.0	14.9	-2.1	-2.4	-0.9	-3.9	-1.9	-2.3	-1.7	-0.6	-2.5	2.3
Time employed in main current job	1.1	1.3	3.1	-0.5	-1.8	-1.5	-0.9	-1.3	-1.6	-0.8	-0.8	-0.8	0.2
Birth weight	1.1	2.3	4.9	-2.2	-1.6	-1.3	-1.2	-1.2	-1.9	-1.5	-1.5	-1.4	1.1
Mean time to correctly identify matches	1.1	2.2	5.2	-1.4	-2.0	-1.1	-2.2	-1.6	-2.3	-0.8	-0.4	-1.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	5.8	-2.0	-1.8	-1.8	-1.7	-0.8	-2.4	-1.3	-1.1	-0.1	-0.6
Depressed Affect (Nagel 2018)	1.0	2.2	4.8	2.2	-0.0	1.7	1.7	2.0	0.0	1.5	1.5	1.3	-1.1
Intelligence (Savage-Jansen 2018)	1.0	3.1	9.7	1.5	3.1	1.1	1.6	0.6	2.5	1.5	-0.0	1.9	-1.5
Ovarian Cancer	1.0	1.3	2.4	-1.2	-1.2	-1.1	-1.2	-1.1	-1.5	-1.4	-0.3	-1.0	1.0
Hayfever, allergic rhinitis or eczema	1.0	2.1	4.6	0.5	1.0	1.1	1.9	0.3	1.4	-1.8	-2.1	-1.3	1.9
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	9.9	-2.9	-1.9	-1.7	-1.8	-1.4	-3.1	-1.2	-1.4	-0.9	1.1
Lung cancer (father)	1.0	1.2	2.1	-1.0	-0.2	-1.3	-0.9	-1.5	-0.6	-1.4	-1.0	-1.4	1.0
Exposure to tobacco smoke at home	1.0	1.1	3.2	-1.2	-0.1	-0.9	-0.7	-0.6	0.0	-0.7	-1.4	-1.6	1.8
Medication: Blood pressure	1.0	1.8	3.9	-1.3	-2.0	-1.6	-1.7	-1.3	-1.8	-0.8	-0.3	-1.2	0.5
Hearing aid user	1.0	1.1	2.2	-1.3	-1.5	-0.9	-0.6	-0.6	-0.9	-1.5	-0.3	-1.1	1.1
Medication: Blood pressure	1.0	1.9	5.0	-1.1	-1.2	-2.2	-1.9	-2.0	-1.6	-0.1	-0.9	-0.5	-0.1
Sensitivity / hurt feelings	0.9	1.6	4.7	-0.8	-2.1	-1.7	-1.3	-1.1	-2.2	-0.2	0.1	0.2	-0.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	3.8	-1.0	-1.2	-1.4	-2.0	-0.6	-1.4	0.2	0.7	-0.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.1	-0.7	-1.5	-1.8	-0.8	-1.1	-1.6	-0.5	0.1	-0.8	0.9
Number of live births	0.9	1.3	2.7	-0.2	-1.6	-0.8	-1.5	-1.0	-1.3	-1.2	-1.1	-1.2	0.8
Breastfed as a baby	0.9	1.1	1.8	1.2	1.0	1.0	1.4	1.0	1.3	0.8	1.0	1.0	-0.9
Birth weight of first child	0.9	1.5	2.9	-1.4	-1.2	-1.2	-0.9	-1.5	-1.5	-0.5	-0.2	-1.5	1.7
Peak expiratory flow (PEF)	0.9	2.0	4.3	-2.0	-1.8	-1.1	-0.9	-0.7	-2.1	-0.9	-1.1	-1.2	1.6
Angina (self-reported)	0.9	1.2	2.3	1.3	1.5	0.9	1.3	1.1	1.5	-0.4	1.4	0.3	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	2.0	-0.9	-1.4	-1.4	-1.4	-1.3	-0.9	0.2	-0.5	-0.9	0.6
Comparative height size at age 10	0.9	4.7	10.8	-2.4	-1.8	-1.9	-1.0	-1.3	-1.7	-2.2	-3.3	-2.6	2.4
Irritability	0.9	1.6	4.1	1.8	0.7	1.4	2.0	1.8	1.2	0.7	0.5	0.4	0.0
Pain experienced in last month	0.9	1.5	4.5	1.2	2.1	1.1	0.8	0.5	2.1	0.9	0.5	0.9	-0.6
Height	0.8	14.9	51.0	-1.0	1.1	0.2	1.6	0.9	2.4	-4.0	-5.9	-6.1	7.1
Smoking Status	0.8	1.9	2.6	-1.0	-1.4	-1.3	-1.6	-1.5	-1.2	-1.6	-0.9	-1.6	1.6
Neuroticism	0.8	2.0	4.0	1.8	-0.0	0.7	1.7	1.5	-0.4	1.4	1.4	2.0	-1.6
Medication for hormone replacement therapy	0.8	0.9	2.4	0.2	0.5	1.2	1.5	1.3	0.3	0.9	1.4	0.7	0.1
Taking other prescription medications	0.8	1.2	2.6	-1.2	-1.2	-1.1	-1.6	-1.1	-1.2	-1.2	-0.8	-0.7	0.6
Stomach or abdominal pain in last month	0.8	1.0	3.1	-1.3	-1.7	-0.8	-0.8	0.1	-1.8	-0.8	0.3	-0.5	0.2
Medication: Simvastatin	0.8	1.2	3.3	-0.6	-1.8	-1.1	-1.4	-1.4	-1.0	-0.6	-0.1	-1.1	0.7
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.7	0.6	1.4	1.5	2.2	2.0	1.2	0.8	0.9	1.2	-0.6
Blood clot in the leg (DVT)	0.8	1.1	2.8	-0.4	-0.7	-1.5	-1.3	-1.7	-0.7	-1.2	-0.9	-0.7	0.4
Age at first live birth	0.8	1.4	3.6	0.6	0.9	1.1	1.9	1.7	1.3	1.0	0.4	1.2	-1.0
Medication: Omeprazole	0.8	1.0	2.7	-1.2	-1.1	-0.8	-1.5	-0.6	-1.6	-0.3	-0.3	-0.6	0.5
Medication: Seretide 50 evohaler	0.8	0.9	4.3	0.8	0.0	1.3	0.5	1.0	-0.0	2.1	0.8	0.4	-0.4
Knee pain experienced in last month	0.8	1.2	4.1	-0.9	-2.0	-1.1	-0.6	-0.1	-1.5	-1.0	-0.7	-1.3	0.7
Illnesses of father: Heart disease	0.8	1.1	3.4	1.8	0.4	1.7	0.7	1.4	0.9	0.6	0.8	0.2	0.2
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.3	0.7	-1.1	-0.3	-0.6	0.7	-1.5	0.5	1.5	0.9	-1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.9	-0.3	-0.5	-1.7	-1.1	-1.7	-0.5	-1.1	-0.9	-0.6	0.3
Ulcerative Colitis (UC)	0.7	1.2	4.6	1.2	0.9	2.2	1.0	1.0	1.0	0.5	0.8	1.1	-0.7
Heel T-Score	0.7	5.9	13.8	2.7	3.5	0.7	2.5	2.1	3.7	1.7	2.4	1.8	-1.6
Angina	0.7	0.9	2.0	0.9	1.2	0.6	1.2	0.8	1.4	-0.8	1.1	-0.3	0.5
Medication: Co-codamol	0.7	0.8	2.5	-0.9	-1.5	-0.6	-0.8	-1.0	-1.6	0.2	-0.1	-0.1	-0.4
Relative age voice broke	0.7	1.1	3.2	-0.3	-0.2	-1.4	0.0	-0.4	0.1	-0.9	-1.5	-1.8	1.6
Qualifications: CSEs or equivalent	0.7	0.9	4.6	-0.6	-2.1	-0.4	-0.9	-0.3	-1.6	-0.3	-0.0	-0.2	0.4
Chronic bronchitis/emphysema (father)	0.7	0.9	2.9	1.0	0.7	0.2	0.3	0.6	0.2	0.4	1.2	1.5	-1.7
Allergy	0.7	1.7	3.9	-0.3	-0.5	-0.7	-1.3	-0.1	-1.0	1.9	1.9	1.4	-2.0
Illnesses of siblings	0.7	0.9	2.9	0.4	-0.2	1.7	0.6	1.4	0.7	0.4	1.5	0.9	-0.4
Neuroticism score	0.7	1.4	2.7	1.5	-0.9	-0.2	1.1	0.8	-1.1	1.4	1.0	1.6	-1.4
Alcohol intake versus 10 years previously	0.7	1.0	4.0	-0.6	-2.0	-1.0	-1.4	-0.8	-1.3	0.4	0.3	-0.4	0.1
Falls in the last year	0.7	1.0	3.5	-1.0	-1.2	-0.7	-1.9	-0.2	-0.8	-1.0	0.5	-1.1	0.7
Pulse rate	0.7	1.1	2.6	-1.6	-1.0	-1.5	-1.4	-1.1	-1.2	-0.2	-0.3	-0.3	0.2
Impedance of arm (left)	0.7	3.0	11.8	-1.6	-1.9	-0.3	-3.4	-1.6	-1.8	-1.1	-0.4	-1.7	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.3	-0.9	-1.8	-0.3	-1.1	-0.7	-2.1	-0.3	0.6	-0.2	0.2
Leg fat percentage (right)	0.7	2.5	6.1	-1.0	-1.5	-2.5	-1.0	-1.8	-1.8	-0.8	-2.1	-1.5	1.0
Worry too long after embarrassment	0.7	1.1	3.3	-0.1	-1.1	-0.5	-0.8	-0.3	-1.7	0.5	-0.5	1.5	-1.8
Qualifications: College or University degree	0.7	2.1	5.4	1.2	1.8	2.3	1.3	1.6	1.0	0.9	1.2	1.4	-1.1
Suffer from ‘nerves’	0.7	1.0	4.1	0.9	0.0	0.2	0.3	0.4	-0.6	0.9	0.8	2.0	-1.9
Leg fat-free mass (right)	0.7	3.9	17.8	1.8	2.4	0.4	4.2	2.0	2.2	0.6	-1.4	0.6	-0.1
Leg predicted mass (right)	0.7	3.8	17.7	1.8	2.4	0.4	4.2	2.0	2.2	0.6	-1.5	0.7	-0.2
Miserableness	0.7	1.2	2.0	1.4	-0.8	0.8	1.4	1.2	-0.7	1.3	1.1	1.1	-0.7
Medication: Lisinopril	0.7	0.9	1.9	-1.2	0.0	-1.1	-0.9	-1.4	-0.0	-0.9	-1.1	-1.1	0.5
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.5	-1.3	-1.1	-0.4	-1.4	-0.6	-1.6	-0.3	-0.6	-0.6	0.6
Irritable Bowel Disease (IBD)	0.6	1.5	2.5	1.4	0.9	1.6	1.6	1.5	1.3	1.2	0.3	1.1	-0.9
Verbal and Numeric Reasoning (VNR)	0.6	1.5	6.2	1.1	2.5	0.4	1.5	0.1	1.9	1.0	-0.4	0.9	-0.3
HbA1C	0.6	0.6	1.3	-0.7	-0.8	-0.3	-1.1	-0.6	-0.4	-1.0	-0.6	-0.9	1.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.5	-0.4	-1.4	-0.2	-0.8	-0.9	-1.6	0.0	0.1	-0.6	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.4	1.0	1.4	0.4	0.2	0.7	1.4	1.2	1.2	1.3	-1.6
Mouth/teeth dental problems	0.6	0.8	1.7	-1.0	-0.8	-1.3	-1.2	-1.2	-1.2	0.0	-1.0	-0.2	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.7	-0.6	-1.6	-0.7	-0.7	-0.2	-1.0	-0.8	-0.4	-0.8	1.1
Migraine (self-reported)	0.6	0.8	3.1	-1.3	-1.1	-0.1	-1.2	-0.6	-1.8	-0.2	-0.0	-0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.8	-1.1	-0.4	-0.9	-0.9	-1.4	-1.1	0.3	-0.5	-0.5	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.4	0.1	-1.6	-1.1	-0.3	-0.3	-1.5	0.5	-0.4	0.5	-0.4
Medication for cholesterol	0.6	0.9	2.7	1.0	1.4	1.2	0.9	0.8	1.6	-0.7	-0.2	0.0	0.1
Financial situation satisfaction	0.6	0.8	2.3	-0.8	-1.5	-0.4	-0.5	-0.8	-1.1	-0.6	-0.2	-0.9	1.3
Age started oral contraceptive pill	0.6	0.8	3.2	-0.0	0.3	-0.8	1.1	-0.4	0.9	-0.8	-1.8	-0.6	0.8
Mean Putamen Volume	0.5	0.6	1.4	1.2	-0.1	0.2	1.1	0.5	0.4	1.2	0.5	0.9	-0.6
Blood White Count	0.5	4.0	26.9	0.2	-1.9	-0.7	-5.2	-1.0	-1.9	0.6	1.9	-0.8	-0.2
Allergy or Eczema	0.5	1.4	2.8	0.7	1.2	1.0	1.7	0.3	1.5	-1.4	-1.6	-0.7	1.1
Relative age of first facial hair	0.5	1.1	2.8	-0.5	0.1	-0.8	0.3	-0.3	0.6	-1.4	-1.6	-1.6	1.7
Leg fat-free mass (left)	0.5	2.7	13.4	1.2	1.9	-0.3	3.7	1.3	1.6	0.1	-2.0	0.1	0.3
Trunk fat percentage	0.5	2.2	5.8	-0.4	-1.2	-2.0	-0.4	-1.3	-1.1	-0.9	-2.4	-1.9	1.6
Leg predicted mass (left)	0.5	2.8	13.8	1.3	1.9	-0.3	3.7	1.3	1.7	0.2	-2.0	0.2	0.2
Trunk fat mass	0.5	2.0	7.5	-0.2	-0.7	-2.0	0.6	-0.8	-0.6	-0.9	-2.7	-1.8	1.6
Forced vital capacity (FVC)	0.5	1.8	4.1	0.3	1.4	1.6	0.9	1.6	0.2	1.4	1.3	2.0	-1.5
Worrier / anxious feelings	0.5	0.9	3.3	-0.6	-1.1	-1.2	-0.4	-1.0	-1.8	0.1	0.1	0.8	-1.0
Gout (self-reported)	0.5	0.7	1.0	1.0	0.6	-0.8	0.8	1.0	0.8	1.0	0.6	0.8	-0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.2	-1.0	-0.9	-0.5	-1.5	-0.4	-1.0	-0.6	0.4	-0.4	0.4
Arm fat-free mass (right)	0.5	2.6	12.8	1.2	1.9	0.0	3.6	1.5	1.8	0.1	-1.6	0.1	0.4
Number of children fathered	0.5	0.5	1.6	0.4	0.1	0.2	0.1	0.4	0.4	1.1	1.0	1.0	-1.3
Emphysema/chronic bronchitis	0.5	0.5	1.3	-0.7	0.2	-0.7	-0.2	-0.6	0.2	-1.1	-0.9	-0.8	0.9
Leg fat mass (right)	0.5	1.8	6.8	-0.4	-0.7	-2.2	0.4	-1.0	-0.9	-0.8	-2.6	-1.5	1.1
Arm predicted mass (right)	0.5	2.4	12.4	0.9	1.6	0.0	3.5	1.5	1.6	0.2	-1.6	-0.0	0.6
Had major operations	0.5	0.6	2.2	-0.9	-0.2	-0.4	-0.1	-0.5	0.2	-0.7	-0.1	-1.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.5	-0.9	-0.6	-0.1	-0.5	-0.3	-0.7	-0.8	-1.7	-1.4	1.9
Whole body fat-free mass	0.5	2.7	13.6	1.1	1.9	-0.1	3.7	1.6	1.8	0.1	-1.8	0.0	0.5
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.5	0.4	1.0	0.2	1.4	0.2	1.6	-0.4	0.1	-0.4	0.5
Whole body water mass	0.5	2.8	13.5	1.2	1.9	0.1	3.7	1.7	1.8	0.2	-1.6	0.2	0.3
Commuting to job workplace: Public transport	0.5	0.6	2.0	-1.0	-0.7	-0.7	-0.9	-0.4	-1.4	-0.6	-0.0	0.3	-0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.7	-0.6	-1.3	-0.3	-0.2	-0.9	-1.0	-0.6	1.3	-0.3	0.3
Heart disease (siblings)	0.5	0.7	2.1	-0.2	-0.2	0.1	-0.3	-0.3	-0.6	1.5	1.3	0.9	-1.2
Alcohol drinker status: Previous	0.5	0.6	1.9	0.6	0.9	1.4	0.0	0.8	0.5	0.5	1.1	0.5	-0.2
Bipolar Disorder (2018)	0.4	0.7	1.6	1.0	0.7	1.3	0.4	0.6	0.8	0.9	0.1	1.1	-0.7
Worry (Nagel 2018)	0.4	0.9	3.0	0.8	-0.0	0.5	0.4	0.5	-0.4	0.4	1.3	1.7	-1.7
Lupus	0.4	0.7	2.0	-0.2	-0.9	-0.4	-1.4	-0.2	-1.4	-1.0	-0.5	-0.2	-0.4
Blood Eosinophil Count	0.4	3.4	9.1	-0.6	-0.7	-0.7	-2.4	-1.0	-0.0	-2.7	-1.4	-2.9	3.0
Hand grip strength (right)	0.4	1.2	3.7	-0.1	-1.0	-1.1	0.1	-1.1	-0.7	-0.2	-1.5	-1.5	1.9
Average weekly fortified wine intake	0.4	0.4	1.2	0.3	1.1	1.1	-0.0	0.4	1.1	0.1	0.2	0.4	-0.4
Fed-up feelings	0.4	0.8	2.0	1.1	-1.3	0.5	0.5	0.7	-0.8	1.1	1.4	0.3	0.2
Sitting height	0.4	3.1	10.3	1.0	2.0	1.4	3.2	2.0	2.5	-0.3	-1.4	-0.4	1.0
Past tobacco smoking	0.4	0.6	1.7	-1.3	-0.1	-0.2	0.2	-0.2	0.1	-1.3	-1.3	-0.8	0.9
Nervous feelings	0.4	0.8	2.6	1.0	0.6	0.6	0.6	0.5	-0.1	0.8	1.0	1.6	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.4	-0.5	-1.3	0.2	-1.0	-0.6	-1.6	-0.7	0.3	0.0	0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.1	-0.4	-0.8	-0.2	-0.0	0.3	-1.0	0.2	1.1	0.9	-0.9
Trunk fat-free mass	0.4	2.2	10.4	0.7	1.6	-0.2	3.2	1.3	1.6	-0.3	-1.8	-0.3	0.8
Hip circumference	0.4	1.5	5.5	1.1	1.4	-0.5	2.4	0.8	1.2	0.5	-1.9	-0.0	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	3.1	0.7	-0.3	-0.3	0.6	0.6	-0.1	0.6	1.8	1.1	-0.6
Happiness	0.4	0.5	1.9	-0.1	-0.4	0.6	0.2	0.8	-0.5	1.4	0.8	0.8	-0.5
Depression (self-reported)	0.4	0.5	1.3	1.0	0.6	1.1	0.7	0.7	0.9	-0.4	-0.1	-0.2	0.7
Pulse wave Arterial Stiffness index	0.4	0.5	1.1	-0.4	0.4	-0.1	0.8	-0.0	0.7	-0.5	-0.9	-0.9	1.1
Trunk predicted mass	0.4	2.1	10.3	0.6	1.5	-0.3	3.2	1.3	1.6	-0.3	-1.8	-0.3	0.9
Body fat percentage	0.4	1.7	4.5	-0.4	-1.2	-2.1	-0.4	-1.2	-1.2	-0.7	-2.1	-1.5	1.1
Exposure to tobacco smoke outside home	0.4	0.6	1.5	0.9	1.0	0.1	1.2	0.5	1.2	0.7	-0.3	-0.1	0.3
Pulse wave peak to peak time	0.4	0.5	1.4	0.5	-0.1	0.2	-0.5	0.2	-0.6	0.8	0.9	1.1	-1.2
Shortness of breath walking on level ground	0.4	0.5	1.0	-0.3	-0.4	-0.7	-0.8	-1.0	-0.7	-0.9	-0.4	-0.9	0.3
Whole body fat mass	0.4	1.9	7.3	-0.2	-0.7	-2.0	0.6	-0.8	-0.7	-0.9	-2.7	-1.6	1.4
Chest pain or discomfort	0.4	0.5	2.1	0.4	-0.8	-1.5	-0.8	-0.7	-0.9	-0.1	0.5	-0.3	-0.0
Supplements: Vitamin C	0.4	0.5	2.8	-1.0	-0.4	0.1	-0.0	0.1	0.1	-0.7	-1.7	-0.4	0.4
Eye problems/disorders: Cataract	0.4	0.4	1.1	0.3	-0.3	0.6	0.3	0.9	0.2	0.7	1.0	1.0	-0.4
Back pain experienced in last month	0.4	0.6	1.6	0.6	-0.9	0.1	0.9	0.8	-0.6	0.7	-0.4	1.0	-1.3
Basal metabolic rate	0.4	2.4	11.7	1.0	1.7	-0.2	3.4	1.4	1.6	0.0	-1.9	-0.1	0.6
Leg fat percentage (left)	0.4	1.3	3.6	-0.4	-1.2	-1.9	-0.4	-1.3	-1.3	-0.4	-1.6	-1.1	0.6
Arm fat-free mass (left)	0.4	2.0	10.2	0.9	1.3	-0.0	3.2	1.5	1.4	0.2	-1.5	-0.2	0.8
Number of operations (self-reported)	0.4	0.5	2.6	-0.0	-0.6	0.5	-0.8	-0.5	-0.9	-0.3	1.6	0.2	-0.1
Risk taking	0.4	0.6	2.4	-0.8	-0.9	-0.2	0.0	-0.0	-0.4	-0.8	0.8	-0.8	1.6
Arm predicted mass (left)	0.4	1.9	9.6	0.7	1.1	-0.3	3.1	1.3	1.2	-0.1	-1.8	-0.4	1.0
Bipolar Disorder or Schizophrenia	0.3	0.7	3.3	0.6	0.5	0.2	0.7	0.5	0.4	1.8	-0.1	1.0	-1.0
Neuroticism (Nagel 2018)	0.3	0.8	1.4	0.7	-1.0	0.4	0.3	0.7	-1.1	0.3	1.2	1.1	-1.2
Crohns Disease (2017)	0.3	0.6	1.5	1.0	0.2	0.5	1.2	0.9	0.9	1.1	0.0	0.4	-0.5
Breast Cancer	0.3	0.8	5.2	0.2	0.4	-0.3	2.3	0.3	1.1	0.8	0.5	0.5	-0.3
Prostate Cancer	0.3	0.4	0.9	-0.5	-0.4	0.1	-0.9	-0.7	-0.2	-0.2	-0.9	-0.8	0.9
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	0.3	0.1	-1.0	0.4	-0.4	-0.3	0.4	-0.7	0.9	-0.7
Blood Platelet Count	0.3	3.1	14.9	1.1	0.4	0.7	-2.3	0.5	0.1	2.0	3.9	1.4	-1.6
Supplements: Glucosamine	0.3	0.4	1.3	0.0	0.1	1.1	-0.3	0.7	-0.2	0.3	0.9	0.5	-0.7
Heart attack	0.3	0.4	1.3	-0.6	-0.5	-0.1	-1.1	-0.3	-0.4	-0.4	1.1	-0.0	0.0
Fluid intelligence score	0.3	0.6	1.7	0.2	1.3	-0.8	0.9	-0.7	0.8	0.4	-1.0	0.4	-0.1
Weight	0.3	1.6	5.9	0.5	0.7	-1.2	2.3	0.4	0.7	-0.4	-2.4	-1.0	1.2
Arm fat percentage (right)	0.3	1.4	4.1	-0.2	-1.2	-2.0	-0.2	-1.0	-1.2	-0.5	-1.9	-1.1	0.7
Noisy workplace	0.3	0.3	0.8	0.2	-0.3	-0.5	-0.4	-0.3	-0.9	0.7	0.6	0.5	-0.9
Prospective memory result	0.3	0.3	0.8	-0.9	-0.9	-0.1	-0.6	-0.5	-0.6	0.0	-0.4	-0.6	0.4
Arm fat mass (right)	0.3	1.4	5.3	-0.1	-0.7	-2.0	0.7	-0.6	-0.7	-0.6	-2.3	-1.3	1.1
Length of working week for main job	0.3	0.3	0.9	-0.1	-0.5	-1.0	0.3	-0.2	-0.8	-0.7	-0.4	-0.6	0.5
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.5	1.2	0.6	0.5	0.7	0.6	0.6	0.2	0.3	-0.1	0.4
Medication: Aspirin	0.3	0.4	0.8	-0.7	-0.6	-0.6	-0.9	-0.4	-0.8	-0.2	-0.3	-0.7	0.4
Arm fat percentage (left)	0.3	1.0	3.7	-0.0	-0.9	-1.9	0.1	-0.9	-1.1	-0.3	-1.8	-0.7	0.3
Mood swings	0.3	0.5	2.5	0.4	-1.6	0.2	0.2	0.6	-1.0	0.3	0.4	0.5	-0.2
Eye problems/disorders: Glaucoma	0.3	0.3	1.3	1.1	0.4	0.1	0.6	0.5	0.4	0.9	-0.1	0.3	-0.4
Illnesses of father: High blood pressure	0.3	0.4	2.2	-0.4	-0.4	-0.5	0.3	-0.4	-0.4	-0.2	-1.5	-0.6	0.9
Average weekly beer plus cider intake	0.3	0.5	1.2	0.0	-0.1	-1.0	-0.6	-1.1	-0.3	-0.8	-1.0	-0.8	0.4
Ever depressed for a whole week	0.3	0.4	1.4	-0.6	-1.0	0.6	-0.5	-0.1	-1.2	-0.4	0.6	0.1	-0.3
Unable to work because of sickness or disability	0.3	0.4	1.6	-0.3	-1.3	-0.6	-0.3	-0.3	-0.8	-0.7	0.3	-0.7	0.6
Cholesterol lowering medication	0.3	0.5	1.3	-0.1	-1.2	-0.7	-0.0	-0.3	-1.0	1.0	0.5	0.3	-0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.9	-0.5	-0.4	0.1	-1.1	-0.1	-0.3	-0.3	1.4	0.1	-0.2
Leg fat mass (left)	0.3	1.3	5.0	-0.0	-0.6	-1.9	0.7	-0.7	-0.7	-0.6	-2.2	-1.2	0.8
Schizophrenia vs Biploar Disorder	0.2	0.2	1.3	0.1	-0.1	-0.1	0.4	-0.1	0.1	1.1	0.8	-0.0	-0.5
Alzheimer’s Disease (in mother)	0.2	0.3	1.4	-0.3	0.5	-1.2	0.4	-0.5	0.4	-0.0	-0.5	-0.3	0.2
Coronary Artery Disease (CAD)	0.2	0.3	1.4	0.1	0.1	0.2	-0.3	-0.2	0.5	1.2	0.8	0.1	-0.4
LDL Cholesterol	0.2	0.3	1.2	-0.0	-0.1	-0.0	0.0	-0.3	0.2	-0.9	-0.3	-0.7	1.1
Schizophrenia (2014)	0.2	0.5	3.2	0.1	0.2	-0.5	0.6	0.2	0.1	1.8	0.6	0.7	-0.7
BMI	0.2	1.1	6.3	0.9	0.3	-1.3	2.5	0.4	0.5	-0.0	-1.4	-0.1	0.4
Respiratory disease	0.2	0.5	1.5	-0.3	-0.9	0.2	0.0	-0.4	-0.7	-0.6	-1.0	-0.8	1.2
Average weekly spirits intake	0.2	0.3	1.2	-0.3	-0.9	-0.4	-0.6	0.2	-1.1	0.0	-0.3	0.2	-0.4
Maternal smoking around birth	0.2	0.2	1.7	0.2	-0.1	0.3	-0.4	-0.2	0.1	0.3	1.3	-0.0	0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.1	0.0	-1.0	0.1	0.0	0.1	-1.0	0.4	0.1	0.6	-0.6
Body mass index (BMI)	0.2	0.8	2.8	0.7	0.2	-1.6	1.6	-0.1	0.1	-0.0	-1.7	-0.4	0.2
Number of incorrect matches in round	0.2	0.3	0.9	-0.7	-0.7	-0.2	-0.7	0.2	-0.9	0.1	0.3	0.3	-0.8
Hair/balding pattern: Pattern 2	0.2	0.3	1.5	-0.2	-0.4	-0.8	0.7	-0.1	-0.3	1.2	0.0	0.2	0.2
Qualifications: None of the above	0.2	0.4	1.7	0.8	0.9	-0.3	0.2	0.3	1.3	-0.2	-0.5	-0.0	-0.3
Pain all over the body in last month	0.2	0.2	0.5	-0.3	-0.7	-0.5	-0.7	-0.4	-0.5	0.2	0.6	-0.1	-0.5
Hair/balding pattern: Pattern 3	0.2	0.3	1.3	0.0	0.4	-0.4	-0.7	-0.7	0.5	-1.1	-0.2	-0.3	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.0	0.1	-0.2	-0.6	0.1	0.1	-1.0	-0.1	0.5	0.3	-0.1
Medication: Lansoprazole	0.2	0.2	0.6	0.1	-0.8	0.8	-0.7	0.3	-0.1	0.1	0.1	-0.4	0.2
Standing height	0.2	2.5	8.2	-0.8	0.6	0.3	1.3	0.6	0.9	-1.4	-2.5	-2.1	2.9
Tense / ‘highly strung’	0.2	0.4	1.1	0.7	-0.4	0.2	0.4	0.6	-0.6	0.4	1.1	0.8	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.7	1.8	-0.4	0.3	0.4	0.3	1.3	-0.7	0.7	0.7	1.3	-1.2
Comparative body size at age 10	0.2	0.6	1.5	-0.9	-0.8	-1.2	-0.4	-0.5	-1.1	-1.1	-0.4	-0.4	0.5
Wheeze or whistling in the chest in last year	0.2	0.4	1.3	-0.1	-0.8	-0.9	-0.5	-1.1	-0.7	-0.4	0.0	-0.5	0.1
Health satisfaction	0.2	0.3	1.1	-0.6	-0.8	-0.1	-0.5	-0.4	-1.1	0.4	0.1	-0.2	0.2
Medication: Allopurinol	0.2	0.2	0.5	0.7	0.3	-0.7	0.4	0.6	0.6	0.0	0.4	0.2	-0.6
Heart disease (mother)	0.2	0.2	0.9	0.1	0.0	0.0	-0.1	0.3	-0.2	0.8	0.9	0.3	-0.2
Family relationship satisfaction	0.2	0.2	0.6	-0.4	-0.2	-0.0	0.1	0.4	-0.1	-0.4	0.7	-0.6	0.8
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.8	0.6	0.4	0.1	0.3	0.1	0.8	0.9	0.3	-0.2	0.5
Smoking status: Previous	0.2	0.2	1.0	0.5	-0.2	0.2	-0.6	0.1	-0.4	0.6	1.0	0.3	-0.3
Loneliness, isolation	0.2	0.3	1.1	-0.2	-0.7	-1.0	0.1	-0.3	-1.1	0.0	0.5	0.5	-0.0
Ever had bowel cancer screening	0.2	0.3	1.2	0.4	-0.1	-0.6	0.5	-0.4	0.3	-1.1	-0.4	-0.5	0.3
Friendships satisfaction	0.2	0.3	1.2	0.3	0.2	0.3	0.0	0.5	-0.4	0.3	1.1	0.6	-0.7
Osteoarthritis (self-reported)	0.2	0.2	0.6	-0.5	-0.6	0.4	0.3	0.5	-0.3	-0.6	-0.0	-0.4	0.8
Medication: Aspirin	0.2	0.2	0.7	-0.5	-0.1	-0.4	-0.6	-0.3	-0.4	-0.3	-0.2	-0.8	0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	0.6	-0.8	-0.5	-0.2	-0.6	-0.7	-0.4	-0.6	0.1	-0.6	0.1
Arm fat mass (left)	0.2	1.0	4.3	0.1	-0.4	-1.7	0.9	-0.4	-0.5	-0.4	-2.1	-0.8	0.6
Myopia	0.2	0.3	1.1	-0.0	0.2	0.2	-0.1	-1.1	0.7	-0.4	-0.7	-0.0	-0.5
Supplements: Calcium	0.2	0.2	0.6	0.6	-0.3	0.3	0.2	0.3	0.4	0.7	0.0	-0.5	0.4
Basal cell carcinoma (self-reported)	0.2	0.3	0.9	0.1	0.1	-0.9	-0.2	0.2	-0.5	0.8	0.5	0.2	-0.4
Depression (Nagel 2018)	0.1	0.2	0.7	0.3	-0.2	-0.6	0.1	0.2	-0.6	-0.1	0.8	0.1	-0.2
Schizophrenia (2018)	0.1	0.3	1.4	-0.0	0.0	-0.7	0.5	0.1	-0.1	1.2	-0.3	0.5	-0.7
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	-0.2	0.6	-0.4	0.4	-0.1	0.4	0.2	-0.2	0.2	-0.3
Primary Biliary Cirrhosis	0.1	0.2	0.3	-0.5	-0.5	0.5	-0.3	-0.1	-0.1	-0.3	-0.6	-0.4	0.5
Hand grip strength (left)	0.1	0.1	0.3	0.2	-0.3	0.0	0.2	-0.2	-0.3	0.5	-0.6	-0.4	0.6
Medication: Atenolol	0.1	0.1	0.4	0.3	0.0	0.1	0.0	-0.0	0.4	-0.3	-0.1	0.4	-0.6
Had menopause	0.1	0.1	0.5	-0.3	0.2	-0.7	-0.3	-0.5	-0.1	-0.3	0.4	0.0	0.0
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	0.1	0.2	-0.2	-0.0	-0.3	-0.1	-0.7	-0.3	-0.2	-0.1
Asthma	0.1	0.2	0.7	-0.2	-0.8	0.6	0.0	0.3	-0.6	0.2	0.5	-0.2	0.7
Illnesses of mother	0.1	0.1	0.3	-0.2	0.0	-0.1	0.5	-0.3	0.4	-0.5	-0.5	-0.0	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.2	-0.0	0.2	-0.7	1.1	-0.0	0.3	0.3	0.0	0.1	-0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.5	-0.3	-0.7	-0.5	-0.1	-0.5	-0.6	-0.4	-0.1	-0.3	0.3
Eye problems/disorders: None of the above	0.1	0.1	0.3	0.1	0.5	-0.4	0.2	-0.3	0.1	0.2	-0.4	-0.1	-0.6
Neck or shoulder pain in last month	0.1	0.2	1.1	-0.3	-0.1	1.0	0.2	0.8	-0.2	-0.5	0.2	-0.0	0.1
Pulse rate, automated reading	0.1	0.4	1.2	-0.2	0.0	0.4	-0.5	-0.7	-0.8	1.1	0.5	0.6	-0.7
Qualifications: nursing, teaching	0.1	0.2	0.7	-0.8	0.2	-0.3	0.4	-0.1	0.1	-0.3	-0.6	-0.1	0.4
Asthma (self-reported)	0.1	0.2	0.5	-0.0	-0.7	0.6	0.2	0.3	-0.6	0.3	0.5	-0.1	0.7
Ever taken oral contraceptive pill	0.1	0.1	1.0	-1.0	-0.2	-0.3	-0.4	0.0	0.3	-0.2	-0.2	-0.0	0.3
Hair Pigment	0.0	0.7	1.4	1.1	0.1	1.2	-0.5	0.9	0.5	0.1	1.0	0.9	-1.0
Tanning	0.0	0.5	1.7	-0.0	0.1	-0.2	-0.4	-0.3	-0.5	1.2	0.7	1.0	-1.3
Loud music exposure frequency	0.0	0.0	0.2	0.2	0.1	0.4	-0.2	0.3	-0.2	0.0	0.2	0.1	0.0

Hub : Genes

MAPKBP1

Models

Trait associations