[Hub]/) : Traits : Impedance of arm (right) :

chr1:172,881,827-175,663,031

Best TWAS P=8.03e-10 · Best GWAS P=1.02e-09 conditioned to 0.0846

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ANKRD45 0.11 0.11 bslmm 303 0.12 7.5e-14 -4.57 5.2 2.0e-07 -0.82 0.94 0.06 FALSE
2 GTEx Adrenal Gland RC3H1 0.12 0.06 lasso 2 0.06 3.2e-03 -5.84 5.9 2.9e-09 -0.98 0.04 0.80 FALSE
3 GTEx Artery Tibial RC3H1 0.09 0.07 lasso 2 0.07 2.6e-06 -5.84 5.9 4.0e-09 -0.98 0.03 0.96 FALSE
4 GTEx Breast Mammary Tissue RC3H1 0.17 0.05 enet 30 0.05 2.2e-03 -5.79 5.7 1.5e-08 -0.77 0.04 0.93 FALSE
5 GTEx Breast Mammary Tissue (Male) RC3H1 0.07 0.11 enet 3 0.07 9.9e-03 -5.97 6.0 2.0e-09 -1.00 0.03 0.56 FALSE
6 GTEx Breast Mammary Tissue (Female) RABGAP1L 0.19 0.00 lasso 3 0.01 2.0e-01 -5.91 -5.7 1.2e-08 0.92 0.06 0.40 FALSE
7 GTEx Esophagus Muscularis RC3H1 0.10 0.08 lasso 13 0.06 1.2e-04 -5.91 5.9 3.1e-09 -0.98 0.03 0.97 FALSE
8 GTEx Nerve Tibial RC3H1 0.09 0.06 enet 7 0.07 7.0e-06 -5.84 5.9 4.7e-09 -0.97 0.04 0.96 FALSE
9 GTEx Ovary RC3H1 0.32 0.03 lasso 8 0.07 8.6e-03 -5.91 5.5 3.5e-08 -0.82 0.03 0.54 FALSE
10 GTEx Testis RC3H1 0.13 0.03 enet 24 0.06 8.0e-04 -5.90 5.8 7.1e-09 -0.88 0.04 0.93 FALSE
11 METSIM Adipose SERPINC1 0.10 0.09 bslmm 271 0.09 1.2e-13 -5.79 -6.1 9.4e-10 0.95 0.04 0.96 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma MRPS14 0.12 0.05 lasso 3 0.03 6.5e-04 -5.25 -5.3 1.4e-07 0.95 0.00 0.98 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma DARS2 0.04 0.00 blup 36 0.01 5.9e-04 -0.12 -5.5 3.7e-08 0.66 0.01 0.44 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma RABGAP1L 0.07 0.01 lasso 3 0.01 1.2e-02 -5.25 -5.3 1.2e-07 0.97 0.03 0.94 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma SERPINC1 0.14 0.09 blup 47 0.09 1.2e-17 -5.79 -6.1 1.1e-09 0.93 0.01 0.99 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DARS2 0.14 0.00 blup 37 0.01 8.2e-02 -5.84 -5.6 1.8e-08 0.75 0.00 0.43 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma SERPINC1 0.10 0.06 blup 47 0.06 1.8e-04 -4.87 -5.5 4.3e-08 0.76 0.02 0.79 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SERPINC1 0.13 0.03 blup 47 0.03 1.7e-04 -5.84 -5.6 1.8e-08 0.93 0.01 0.98 FALSE
19 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SERPINC1 0.31 0.07 lasso 2 0.05 6.8e-04 -5.73 -5.6 2.4e-08 0.93 0.01 0.98 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma SERPINC1 0.06 0.02 blup 48 0.02 1.7e-03 -5.79 -5.2 2.2e-07 0.92 0.01 0.95 FALSE
21 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RC3H1 0.15 0.00 blup 58 0.03 1.8e-02 -5.84 -5.4 8.5e-08 0.89 0.02 0.56 FALSE
22 The Cancer Genome Atlas Lung Adenocarcinoma SERPINC1 0.08 0.04 blup 48 0.05 5.8e-07 -5.91 -6.1 8.0e-10 0.84 0.01 0.99 TRUE
23 The Cancer Genome Atlas Lung Adenocarcinoma ZBTB37 0.07 0.00 blup 47 0.03 2.2e-04 3.16 -5.4 5.6e-08 0.66 0.02 0.54 FALSE
24 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CACYBP 0.11 0.05 lasso 2 0.04 9.6e-04 -5.25 -5.3 1.1e-07 0.95 0.00 0.96 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MRPS14 0.12 0.01 lasso 4 0.01 1.1e-01 -5.25 -5.7 1.3e-08 0.94 0.00 0.91 FALSE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SERPINC1 0.32 0.11 enet 10 0.12 1.6e-05 -5.91 -5.8 7.6e-09 0.84 0.01 0.98 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma SERPINC1 0.08 0.01 blup 47 0.03 1.6e-04 -5.79 -6.1 9.4e-10 0.77 0.01 0.87 FALSE
28 The Cancer Genome Atlas Soft Tissue Sarcoma SERPINC1 0.12 0.08 lasso 5 0.08 2.4e-05 -5.84 -5.7 1.2e-08 0.91 0.01 0.97 FALSE
29 The Cancer Genome Atlas Stomach Adenocarcinoma SERPINC1 0.09 0.04 lasso 5 0.04 5.8e-04 -5.91 -5.4 5.9e-08 0.96 0.01 0.98 FALSE
30 The Cancer Genome Atlas Testicular Germ Cell Tumors RC3H1 0.13 -0.01 blup 58 0.01 1.4e-01 -5.84 -5.6 2.4e-08 0.80 0.01 0.25 FALSE