[Hub]/) : Traits : Impedance of arm (right) :

chr16:19,016,966-20,596,558

Best TWAS P=2.87e-16 · Best GWAS P=1.86e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GPRC5B 0.11 0.05 lasso 5 0.04 5.2e-06 6.9 -6.6 3.9e-11 -0.67 0.44 0.55 FALSE
2 CommonMind Brain Pre-frontal Cortex IQCK 0.06 0.04 lasso 5 0.06 2.3e-07 6.7 -6.2 5.8e-10 -0.67 0.23 0.76 FALSE
3 GTEx Adipose Subcutaneous KNOP1 0.26 0.38 lasso 6 0.40 9.0e-35 6.9 6.9 5.3e-12 0.69 0.37 0.63 FALSE
4 GTEx Adipose Subcutaneous GPRC5B 0.07 0.04 lasso 4 0.03 1.3e-03 7.5 -8.2 2.9e-16 -0.96 0.01 0.98 TRUE
5 GTEx Adipose Subcutaneous AC002550.5 0.41 0.50 enet 17 0.52 7.9e-49 6.9 6.8 1.2e-11 0.74 0.38 0.62 FALSE
6 GTEx Adipose Visceral Omentum KNOP1 0.39 0.52 lasso 3 0.53 9.1e-32 6.9 7.2 5.1e-13 0.75 0.41 0.59 FALSE
7 GTEx Adipose Visceral Omentum AC002550.5 0.40 0.51 lasso 1 0.50 8.1e-30 6.9 6.8 7.3e-12 0.69 0.42 0.58 FALSE
8 GTEx Adrenal Gland KNOP1 0.40 0.34 lasso 4 0.40 1.1e-15 7.3 7.4 1.0e-13 0.79 0.09 0.91 FALSE
9 GTEx Adrenal Gland AC002550.5 0.37 0.39 enet 28 0.40 1.6e-15 6.9 7.2 6.6e-13 0.75 0.38 0.62 FALSE
10 GTEx Artery Aorta KNOP1 0.50 0.48 lasso 8 0.49 4.0e-30 6.9 7.3 2.1e-13 0.76 0.42 0.58 FALSE
11 GTEx Artery Aorta AC002550.5 0.52 0.52 lasso 7 0.49 1.9e-30 6.9 7.2 6.0e-13 0.75 0.42 0.58 FALSE
12 GTEx Artery Coronary KNOP1 0.28 0.25 lasso 7 0.32 2.5e-11 6.9 7.5 5.0e-14 0.82 0.06 0.94 FALSE
13 GTEx Artery Coronary AC002550.5 0.30 0.34 enet 11 0.37 1.5e-13 6.9 7.3 2.9e-13 0.79 0.23 0.77 FALSE
14 GTEx Artery Tibial KNOP1 0.16 0.22 lasso 3 0.22 8.9e-17 6.9 6.9 7.0e-12 0.69 0.47 0.53 FALSE
15 GTEx Artery Tibial AC002550.5 0.31 0.36 lasso 8 0.39 6.8e-32 6.9 7.1 9.5e-13 0.73 0.40 0.60 FALSE
16 GTEx Brain Caudate basal ganglia KNOP1 0.58 0.37 lasso 2 0.39 3.7e-12 6.9 6.8 7.2e-12 0.69 0.44 0.56 FALSE
17 GTEx Brain Caudate basal ganglia AC002550.5 0.64 0.42 lasso 2 0.43 1.0e-13 6.9 6.9 6.4e-12 0.69 0.44 0.56 FALSE
18 GTEx Brain Cerebellar Hemisphere KNOP1 0.46 0.37 lasso 8 0.34 2.0e-09 6.9 6.6 5.0e-11 0.68 0.43 0.57 FALSE
19 GTEx Brain Cerebellar Hemisphere AC002550.5 0.50 0.44 lasso 8 0.43 2.0e-12 6.6 6.7 1.7e-11 0.69 0.47 0.53 FALSE
20 GTEx Brain Cerebellum KNOP1 0.44 0.38 lasso 3 0.34 1.0e-10 6.9 6.4 1.4e-10 0.68 0.40 0.59 FALSE
21 GTEx Brain Cerebellum AC002550.5 0.49 0.52 lasso 2 0.52 9.7e-18 6.9 6.9 6.0e-12 0.69 0.40 0.60 FALSE
22 GTEx Brain Cortex KNOP1 0.30 0.21 lasso 4 0.26 1.1e-07 6.9 6.7 3.0e-11 0.70 0.26 0.72 FALSE
23 GTEx Brain Cortex AC002550.5 0.50 0.46 lasso 6 0.46 3.9e-14 6.9 7.0 3.7e-12 0.71 0.43 0.57 FALSE
24 GTEx Brain Frontal Cortex BA9 KNOP1 0.43 0.33 lasso 14 0.30 1.0e-08 6.9 7.2 6.5e-13 0.76 0.39 0.59 FALSE
25 GTEx Brain Frontal Cortex BA9 AC002550.5 0.53 0.40 enet 15 0.43 9.0e-13 6.9 6.9 4.0e-12 0.71 0.48 0.52 FALSE
26 GTEx Brain Hippocampus KNOP1 0.25 0.25 lasso 7 0.14 3.2e-04 6.9 6.7 2.2e-11 0.70 0.34 0.46 FALSE
27 GTEx Brain Hippocampus AC002550.5 0.25 0.24 lasso 4 0.22 6.9e-06 6.6 6.8 9.8e-12 0.70 0.32 0.49 FALSE
28 GTEx Brain Hypothalamus KNOP1 0.31 0.37 lasso 2 0.34 1.1e-08 6.9 6.8 8.2e-12 0.70 0.18 0.78 FALSE
29 GTEx Brain Hypothalamus AC002550.5 0.37 0.47 lasso 2 0.46 3.1e-12 6.9 7.1 1.3e-12 0.73 0.24 0.76 FALSE
30 GTEx Brain Nucleus accumbens basal ganglia KNOP1 0.34 0.38 lasso 5 0.37 1.0e-10 6.7 7.0 2.7e-12 0.74 0.40 0.60 FALSE
31 GTEx Brain Nucleus accumbens basal ganglia AC002550.5 0.36 0.41 enet 20 0.42 2.2e-12 6.9 6.2 4.7e-10 0.68 0.49 0.51 FALSE
32 GTEx Brain Putamen basal ganglia KNOP1 0.31 0.23 enet 13 0.29 1.3e-07 6.9 5.9 3.0e-09 0.68 0.38 0.54 FALSE
33 GTEx Brain Putamen basal ganglia AC002550.5 0.59 0.48 enet 23 0.58 1.2e-16 6.9 7.2 4.1e-13 0.62 0.46 0.54 FALSE
34 GTEx Breast Mammary Tissue AC002550.5 0.37 0.49 enet 13 0.50 3.3e-29 6.9 7.3 3.3e-13 0.80 0.12 0.88 FALSE
35 GTEx Breast Mammary Tissue (Male) AC002550.5 0.37 0.29 lasso 3 0.35 4.8e-09 7.2 7.6 2.6e-14 0.90 0.04 0.96 FALSE
36 GTEx Breast Mammary Tissue (Female) AC002550.5 0.36 0.26 enet 19 0.33 1.3e-10 7.3 6.7 2.8e-11 0.75 0.06 0.94 FALSE
37 GTEx Cells EBV-transformed lymphocytes KNOP1 0.70 0.58 lasso 7 0.59 2.1e-23 6.7 6.8 1.2e-11 0.70 0.51 0.49 FALSE
38 GTEx Cells EBV-transformed lymphocytes AC002550.5 0.81 0.65 lasso 15 0.64 2.9e-26 6.9 6.9 4.6e-12 0.70 0.49 0.51 FALSE
39 GTEx Cells Transformed fibroblasts KNOP1 0.07 0.08 lasso 5 0.08 2.5e-06 6.9 6.9 6.3e-12 0.69 0.39 0.58 FALSE
40 GTEx Cells Transformed fibroblasts AC002550.5 0.12 0.10 enet 15 0.10 4.3e-08 6.9 6.7 2.2e-11 0.70 0.39 0.61 FALSE
41 GTEx Colon Sigmoid KNOP1 0.32 0.35 lasso 6 0.32 4.9e-12 6.9 7.4 1.4e-13 0.80 0.16 0.84 FALSE
42 GTEx Colon Sigmoid AC002550.5 0.41 0.38 lasso 2 0.35 4.2e-13 6.9 6.6 4.5e-11 0.65 0.42 0.58 FALSE
43 GTEx Colon Transverse KNOP1 0.22 0.23 enet 19 0.24 9.8e-12 6.9 7.2 5.4e-13 0.81 0.16 0.84 FALSE
44 GTEx Colon Transverse AC002550.5 0.35 0.36 enet 15 0.41 5.0e-21 6.9 7.5 6.7e-14 0.81 0.38 0.62 FALSE
45 GTEx Esophagus Gastroesophageal Junction KNOP1 0.51 0.44 enet 22 0.56 5.3e-24 7.3 7.7 1.9e-14 0.84 0.04 0.96 FALSE
46 GTEx Esophagus Gastroesophageal Junction AC002550.5 0.62 0.54 enet 35 0.63 4.4e-29 6.7 7.6 3.1e-14 0.77 0.40 0.60 FALSE
47 GTEx Esophagus Mucosa KNOP1 0.31 0.43 lasso 5 0.43 5.6e-31 6.9 7.1 1.6e-12 0.74 0.43 0.57 FALSE
48 GTEx Esophagus Mucosa AC002550.5 0.38 0.52 lasso 3 0.51 2.6e-39 6.9 6.8 1.3e-11 0.71 0.42 0.58 FALSE
49 GTEx Esophagus Muscularis KNOP1 0.47 0.51 lasso 10 0.56 1.9e-40 6.9 7.2 5.4e-13 0.74 0.40 0.60 FALSE
50 GTEx Esophagus Muscularis AC002550.5 0.40 0.49 lasso 7 0.47 1.4e-31 6.9 7.0 2.9e-12 0.71 0.40 0.60 FALSE
51 GTEx Heart Atrial Appendage KNOP1 0.43 0.45 lasso 3 0.44 6.5e-22 6.9 6.9 5.3e-12 0.70 0.42 0.58 FALSE
52 GTEx Heart Atrial Appendage AC002550.5 0.46 0.50 lasso 2 0.49 7.4e-25 6.9 6.8 7.4e-12 0.69 0.42 0.58 FALSE
53 GTEx Heart Left Ventricle KNOP1 0.34 0.48 lasso 2 0.44 2.3e-25 6.9 7.1 1.6e-12 0.73 0.43 0.57 FALSE
54 GTEx Heart Left Ventricle AC002550.5 0.38 0.41 lasso 2 0.38 2.8e-21 6.9 6.8 7.5e-12 0.69 0.42 0.58 FALSE
55 GTEx Liver KNOP1 0.23 0.21 lasso 7 0.25 1.4e-07 6.7 7.5 7.2e-14 0.81 0.12 0.86 FALSE
56 GTEx Liver AC002550.5 0.43 0.42 enet 13 0.47 1.1e-14 6.7 7.4 1.5e-13 0.85 0.15 0.85 FALSE
57 GTEx Lung KNOP1 0.34 0.48 lasso 8 0.49 4.0e-42 6.9 7.2 7.2e-13 0.76 0.43 0.57 FALSE
58 GTEx Lung GPRC5B 0.08 0.05 lasso 4 0.06 2.4e-05 6.7 -6.7 1.7e-11 -0.73 0.47 0.49 FALSE
59 GTEx Lung AC002550.5 0.43 0.55 lasso 9 0.54 6.4e-48 6.9 7.0 1.9e-12 0.73 0.44 0.56 FALSE
60 GTEx Muscle Skeletal KNOP1 0.29 0.45 lasso 6 0.44 7.0e-48 6.9 6.9 5.8e-12 0.70 0.45 0.55 FALSE
61 GTEx Muscle Skeletal AC002550.5 0.35 0.53 lasso 6 0.52 3.2e-59 6.9 7.1 1.7e-12 0.73 0.44 0.56 FALSE
62 GTEx Nerve Tibial KNOP1 0.44 0.59 lasso 4 0.59 4.6e-51 6.9 6.9 6.8e-12 0.69 0.42 0.58 FALSE
63 GTEx Nerve Tibial AC002550.5 0.39 0.55 lasso 4 0.55 2.0e-45 6.9 6.9 6.5e-12 0.69 0.42 0.58 FALSE
64 GTEx Ovary KNOP1 0.61 0.64 lasso 7 0.57 4.4e-17 6.9 7.2 4.9e-13 0.77 0.40 0.60 FALSE
65 GTEx Ovary AC002550.5 0.66 0.56 lasso 4 0.47 3.6e-13 6.9 6.7 2.9e-11 0.72 0.40 0.60 FALSE
66 GTEx Pancreas KNOP1 0.42 0.37 lasso 11 0.40 4.2e-18 6.7 7.2 5.8e-13 0.84 0.34 0.66 FALSE
67 GTEx Pancreas AC002550.5 0.37 0.36 lasso 12 0.36 3.2e-16 6.9 7.3 2.1e-13 0.76 0.35 0.65 FALSE
68 GTEx Pituitary KNOP1 0.40 0.36 lasso 3 0.30 3.1e-08 6.9 7.2 8.5e-13 0.76 0.25 0.72 FALSE
69 GTEx Pituitary AC002550.5 0.52 0.53 lasso 3 0.52 3.8e-15 6.9 6.8 9.1e-12 0.69 0.42 0.58 FALSE
70 GTEx Prostate KNOP1 0.54 0.32 lasso 11 0.24 9.4e-07 6.9 6.6 4.8e-11 0.68 0.37 0.58 FALSE
71 GTEx Prostate AC002550.5 0.49 0.25 lasso 8 0.33 5.7e-09 6.9 7.1 9.8e-13 0.74 0.32 0.68 FALSE
72 GTEx Skin Not Sun Exposed Suprapubic KNOP1 0.37 0.43 lasso 3 0.41 5.0e-24 6.7 7.0 3.0e-12 0.74 0.69 0.31 FALSE
73 GTEx Skin Not Sun Exposed Suprapubic AC002550.5 0.44 0.43 enet 24 0.43 1.2e-25 6.7 7.3 2.3e-13 0.79 0.55 0.45 FALSE
74 GTEx Skin Sun Exposed Lower leg KNOP1 0.33 0.47 lasso 9 0.48 5.4e-44 6.9 7.2 4.6e-13 0.76 0.46 0.54 FALSE
75 GTEx Skin Sun Exposed Lower leg AC002550.5 0.38 0.56 lasso 6 0.57 8.6e-58 6.9 7.1 1.1e-12 0.74 0.43 0.57 FALSE
76 GTEx Small Intestine Terminal Ileum AC002550.5 0.42 0.32 lasso 2 0.31 1.2e-07 6.9 6.9 6.4e-12 0.69 0.26 0.67 FALSE
77 GTEx Spleen KNOP1 0.45 0.36 lasso 7 0.41 1.2e-11 6.9 7.0 2.0e-12 0.74 0.20 0.80 FALSE
78 GTEx Spleen AC002550.5 0.53 0.44 enet 12 0.46 2.9e-13 6.9 6.9 6.3e-12 0.70 0.40 0.60 FALSE
79 GTEx Stomach KNOP1 0.28 0.21 lasso 6 0.21 1.8e-10 4.3 6.2 6.1e-10 0.77 0.06 0.94 FALSE
80 GTEx Stomach AC002550.5 0.36 0.26 lasso 7 0.32 4.8e-16 6.9 6.5 5.8e-11 0.73 0.43 0.57 FALSE
81 GTEx Testis KNOP1 0.37 0.34 lasso 5 0.30 8.1e-14 6.9 6.9 6.3e-12 0.70 0.42 0.58 FALSE
82 GTEx Testis AC002550.5 0.49 0.57 lasso 5 0.56 7.7e-30 6.9 7.3 3.7e-13 0.77 0.42 0.58 FALSE
83 GTEx Thyroid KNOP1 0.35 0.41 enet 11 0.43 4.7e-36 6.9 6.8 1.1e-11 0.71 0.42 0.58 FALSE
84 GTEx Thyroid AC002550.5 0.43 0.49 enet 36 0.49 8.6e-43 6.9 5.7 1.2e-08 0.65 0.43 0.57 FALSE
85 GTEx Uterus KNOP1 0.29 0.22 enet 10 0.18 1.7e-04 6.9 6.7 1.8e-11 0.73 0.10 0.68 FALSE
86 GTEx Uterus AC002550.5 0.51 0.40 lasso 12 0.36 2.3e-08 6.9 6.9 6.0e-12 0.76 0.19 0.77 FALSE
87 GTEx Vagina KNOP1 0.43 0.35 lasso 5 0.36 4.2e-09 6.9 7.2 5.2e-13 0.74 0.23 0.77 FALSE
88 GTEx Vagina AC002550.5 0.47 0.24 lasso 4 0.38 1.0e-09 6.9 6.7 2.0e-11 0.71 0.34 0.65 FALSE
89 GTEx Whole Blood KNOP1 0.08 0.04 lasso 3 0.04 1.7e-04 6.9 7.6 2.2e-14 0.86 0.09 0.90 FALSE
90 GTEx Whole Blood AC002550.5 0.15 0.10 lasso 4 0.10 6.3e-10 6.9 6.9 5.5e-12 0.69 0.41 0.59 FALSE
91 METSIM Adipose KNOP1 0.15 0.23 bslmm 442 0.24 9.4e-35 6.9 6.8 7.7e-12 0.71 0.47 0.53 FALSE
92 NTR Blood C16orf88 0.03 0.03 bslmm 453 0.03 2.2e-09 6.5 6.6 4.0e-11 0.70 0.52 0.48 FALSE
93 ROSMAP Brain Pre-frontal Cortex KNOP1 0.56 0.72 lasso 6 0.72 3.0e-135 6.9 6.9 5.3e-12 0.68 0.38 0.62 FALSE
94 ROSMAP Brain Pre-frontal Cortex CTD-2380F24.1 0.20 0.29 lasso 1 0.29 2.4e-37 6.8 -6.8 7.9e-12 -0.69 0.53 0.47 FALSE
95 The Cancer Genome Atlas Bladder Urothelial Carcinoma C16orf88 0.08 0.08 lasso 2 0.08 4.9e-07 6.9 7.1 1.2e-12 0.71 0.03 0.97 FALSE
96 The Cancer Genome Atlas Bladder Urothelial Carcinoma IQCK 0.05 0.02 blup 73 0.03 1.0e-03 7.3 7.3 3.8e-13 0.84 0.01 0.96 FALSE
97 The Cancer Genome Atlas Breast Invasive Carcinoma C16orf62 0.04 0.02 lasso 3 0.02 6.6e-06 6.9 6.0 1.7e-09 0.68 0.01 0.98 FALSE
98 The Cancer Genome Atlas Breast Invasive Carcinoma C16orf88 0.10 0.08 lasso 3 0.08 7.1e-17 6.9 7.2 4.3e-13 0.76 0.03 0.97 FALSE
99 The Cancer Genome Atlas Breast Invasive Carcinoma IQCK 0.03 0.03 blup 73 0.03 1.6e-07 6.7 7.1 1.7e-12 0.81 0.03 0.97 FALSE
100 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C16orf88 0.16 0.09 enet 10 0.14 2.2e-07 6.8 6.5 7.7e-11 0.74 0.02 0.97 FALSE
101 The Cancer Genome Atlas Colon Adenocarcinoma C16orf88 0.10 0.04 blup 37 0.04 1.6e-03 6.8 7.1 1.3e-12 0.69 0.03 0.93 FALSE
102 The Cancer Genome Atlas Glioblastoma Multiforme C16orf88 0.34 0.07 lasso 3 0.12 1.5e-04 7.3 6.6 5.5e-11 0.78 0.00 0.92 FALSE
103 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C16orf88 0.22 0.08 lasso 3 0.08 2.0e-09 7.3 7.4 1.8e-13 0.82 0.00 1.00 FALSE
104 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IQCK 0.04 0.03 lasso 2 0.04 7.5e-05 6.9 7.1 1.7e-12 0.69 0.08 0.76 FALSE
105 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C16orf88 0.15 0.10 lasso 4 0.10 8.2e-12 6.9 6.7 2.3e-11 0.66 0.03 0.97 FALSE
106 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C16orf88 0.07 0.05 lasso 2 0.05 7.7e-04 7.3 7.4 1.7e-13 0.83 0.00 0.93 FALSE
107 The Cancer Genome Atlas Brain Lower Grade Glioma C16orf88 0.22 0.30 lasso 8 0.30 1.2e-34 6.9 6.9 5.0e-12 0.69 0.04 0.96 FALSE
108 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C16orf88 0.10 0.12 lasso 2 0.08 9.5e-05 6.9 6.7 2.0e-11 0.69 0.02 0.96 FALSE
109 The Cancer Genome Atlas Lung Adenocarcinoma C16orf62 0.05 0.03 blup 114 0.02 9.6e-04 6.8 5.6 2.4e-08 0.61 0.01 0.97 FALSE
110 The Cancer Genome Atlas Lung Adenocarcinoma C16orf88 0.15 0.12 blup 37 0.12 1.1e-13 6.9 6.7 2.0e-11 0.70 0.04 0.96 FALSE
111 The Cancer Genome Atlas Lung Adenocarcinoma IQCK 0.09 0.04 lasso 6 0.04 4.9e-05 6.6 6.4 1.4e-10 0.73 0.09 0.91 FALSE
112 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C16orf88 0.10 0.10 lasso 3 0.13 3.7e-14 7.3 7.4 1.2e-13 0.80 0.01 0.99 FALSE
113 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IQCK 0.03 0.03 lasso 3 0.02 7.2e-04 7.3 7.4 1.0e-13 0.94 0.01 0.98 FALSE
114 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IQCK 0.07 0.02 blup 73 0.04 1.7e-03 6.6 6.0 2.4e-09 0.67 0.03 0.64 FALSE
115 The Cancer Genome Atlas Pancreatic Adenocarcinoma C16orf88 0.12 0.06 lasso 7 0.05 2.8e-03 6.9 6.9 5.3e-12 0.68 0.04 0.84 FALSE
116 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C16orf88 0.34 0.21 lasso 4 0.17 3.1e-07 7.3 7.4 1.0e-13 0.82 0.00 1.00 FALSE
117 The Cancer Genome Atlas Prostate Adenocarcinoma C16orf88 0.18 0.14 lasso 4 0.14 2.4e-14 6.9 6.6 3.4e-11 0.69 0.04 0.96 FALSE
118 The Cancer Genome Atlas Prostate Adenocarcinoma IQCK 0.04 0.01 blup 73 0.01 1.8e-02 6.8 7.4 1.4e-13 0.77 0.05 0.59 FALSE
119 The Cancer Genome Atlas Soft Tissue Sarcoma C16orf88 0.16 0.14 lasso 3 0.13 5.3e-08 5.2 5.2 2.6e-07 0.61 0.14 0.86 FALSE
120 The Cancer Genome Atlas Testicular Germ Cell Tumors C16orf88 0.09 0.08 lasso 2 0.06 4.2e-03 6.9 7.0 2.2e-12 0.68 0.03 0.80 FALSE
121 The Cancer Genome Atlas Thyroid Carcinoma C16orf88 0.20 0.18 blup 37 0.19 6.3e-18 6.9 6.9 4.2e-12 0.68 0.04 0.96 FALSE
122 The Cancer Genome Atlas Thyroid Carcinoma GPRC5B 0.06 0.01 blup 38 0.01 2.4e-02 6.6 7.2 6.4e-13 0.67 0.01 0.08 FALSE
123 The Cancer Genome Atlas Thyroid Carcinoma IQCK 0.05 0.04 lasso 3 0.03 4.3e-04 6.9 7.0 2.2e-12 0.68 0.10 0.83 FALSE