TWAS hub - C16orf62

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1220	0.0420	8.1e-04	0.035	NA	0.025	NA	0.033	7.2e-04	NA	3.7e-03	NA	1.1e-03
2	GTEx	Artery Aorta	0.1740	0.0510	2.4e-05	0.166	NA	0.131	NA	0.139	1.8e-09	NA	1.1e-07	NA	4.4e-08
3	GTEx	Artery Tibial	0.1296	0.0410	8.6e-05	0.088	NA	0.096	NA	0.105	2.1e-07	NA	5.5e-08	NA	1.5e-08
4	GTEx	Cells Transformed fibroblasts	0.2790	0.0530	7.6e-09	0.211	NA	0.220	NA	0.223	9.6e-16	NA	1.9e-16	NA	1.2e-16
5	GTEx	Colon Transverse	0.2290	0.0680	1.9e-04	0.010	NA	0.043	NA	0.041	1.0e-01	NA	4.0e-03	NA	4.7e-03
6	GTEx	Esophagus Mucosa	0.0870	0.0310	1.5e-03	0.066	NA	0.035	NA	0.045	3.4e-05	NA	2.2e-03	NA	5.4e-04
7	GTEx	Esophagus Muscularis	0.1220	0.0440	7.2e-04	0.005	NA	0.011	NA	0.012	1.5e-01	NA	7.0e-02	NA	5.8e-02
8	GTEx	Nerve Tibial	0.2312	0.0554	8.3e-07	0.120	NA	0.094	NA	0.135	8.4e-09	NA	3.8e-07	NA	8.7e-10
9	METSIM	Adipose	0.0903	0.0297	7.8e-05	0.011	0.011	0.027	0.015	0.017	6.3e-03	7.8e-03	5.7e-05	2.1e-03	1.0e-03
10	ROSMAP	Brain Pre-frontal Cortex	0.1229	0.0322	6.8e-06	0.086	0.043	0.070	0.057	0.077	3.5e-11	3.0e-06	2.8e-09	8.0e-08	3.8e-10
11	TCGA	Breast Invasive Carcinoma	0.0364	0.0135	1.1e-05	0.025	0.024	0.022	NA	0.025	6.7e-06	7.3e-06	1.7e-05	NA	6.6e-06
12	TCGA	Cervical Squamous Cell Carcinoma	0.1180	0.0560	9.5e-03	0.012	0.028	-0.005	NA	0.004	8.2e-02	1.5e-02	7.3e-01	NA	2.0e-01
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0745	0.0257	6.3e-07	0.037	0.057	0.045	NA	0.036	5.0e-05	5.3e-07	7.3e-06	NA	5.6e-05
14	TCGA	Brain Lower Grade Glioma	0.0819	0.0284	9.9e-07	0.011	0.041	0.043	NA	0.039	2.0e-02	1.7e-05	1.1e-05	NA	2.5e-05
15	TCGA	Lung Adenocarcinoma	0.0517	0.0221	1.9e-04	0.030	0.023	0.015	NA	0.014	1.8e-04	9.6e-04	6.7e-03	NA	8.1e-03
16	TCGA	Lung Squamous Cell Carcinoma	0.0386	0.0196	2.9e-03	0.008	0.020	0.032	NA	0.024	3.9e-02	2.3e-03	1.4e-04	NA	7.8e-04
17	TCGA	Pheochromocytoma and Paraganglioma	0.1520	0.0720	2.2e-03	0.032	0.059	0.109	NA	0.111	1.9e-02	2.3e-03	4.3e-05	NA	3.5e-05
18	TCGA	Soft Tissue Sarcoma	0.1260	0.0470	1.4e-04	0.066	0.072	0.089	NA	0.057	9.5e-05	4.3e-05	5.9e-06	NA	2.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Comparative body size at age 10	7.8	21.5	55.1	-3.7	-3.0	-4.6	-2.6	-5.0	0.8	-4.0	-3.7	-0.1	-2.1	-7.0	-1.2	-4.3	-5.6	-7.2	-6.6	-7.4	-5.1
Body Mass Index (BMI) (2010)	6.8	9.4	25.2	-1.9	-2.4	-3.2	-2.2	-2.6	1.2	-2.1	-2.6	0.3	-1.8	-4.3	-1.7	-3.1	-4.3	-5.0	-4.0	-4.0	-3.7
Vitamin and mineral supplements	5.6	7.5	12.8	-3.2	-2.9	-2.9	-3.3	-3.6	-1.8	-2.4	-3.3	-1.4	-3.6	-1.8	-0.8	-3.1	-2.8	-2.0	-3.0	-2.0	-3.4
Impedance of leg (left)	4.7	22.8	49.0	4.9	3.2	4.3	3.4	5.6	1.0	4.6	4.5	0.3	3.2	6.8	0.3	4.9	5.7	6.4	6.4	7.0	5.4
Impedance of whole body	4.4	22.6	51.8	4.8	3.0	4.1	3.2	4.8	0.2	4.1	4.4	-0.3	3.5	7.2	1.1	4.7	6.3	6.8	6.1	6.8	5.6
Impedance of leg (right)	4.2	20.2	42.1	4.3	3.1	3.9	3.1	5.5	0.9	4.1	4.2	-0.1	2.9	6.5	-0.3	5.2	5.3	6.3	5.8	6.4	5.1
BMI	4.1	24.0	60.2	-4.3	-2.9	-4.7	-2.4	-4.8	0.1	-5.2	-3.7	1.7	-2.7	-7.8	-0.8	-5.0	-5.7	-7.5	-7.3	-7.2	-4.9
Hearing aid user	3.9	4.4	10.0	-0.9	-2.5	-3.2	-2.1	-1.8	0.2	-0.9	-2.0	1.3	-2.4	-1.7	-3.0	-1.2	-3.0	-1.8	-2.2	-1.8	-2.8
Schizophrenia vs Biploar Disorder	3.8	5.1	11.8	2.3	2.5	3.1	2.2	3.4	0.4	2.4	2.5	2.5	2.0	0.9	1.6	2.2	1.8	1.5	2.9	2.5	1.6
Schizophrenia (2014)	3.6	8.0	15.9	2.8	3.0	4.0	3.1	3.1	3.6	2.5	3.5	2.0	2.9	2.1	0.8	2.6	1.8	1.0	3.9	2.8	3.0
Multivitamins +/- minerals	3.6	4.6	8.8	2.8	2.5	2.2	2.8	2.5	1.7	2.2	3.0	1.1	2.9	0.8	0.0	2.4	1.9	1.2	2.0	1.4	2.7
Tense / ‘highly strung’	3.6	6.0	11.8	2.5	2.3	3.0	2.4	1.8	1.0	1.8	2.6	2.3	2.5	2.1	1.9	2.1	2.7	2.2	3.3	3.4	2.9
Handedness (chirality/laterality): Left-handed	3.6	4.4	9.0	2.4	2.6	2.2	2.3	3.0	2.0	2.4	2.5	2.8	2.8	0.1	0.5	2.2	1.0	0.7	1.8	1.6	2.0
Impedance of arm (left)	3.5	16.4	43.7	3.7	2.3	3.5	2.5	3.5	-0.3	3.0	3.4	-0.6	3.0	6.6	1.6	3.9	5.8	6.3	5.2	5.5	4.9
Age when periods started (menarche)	3.4	8.1	16.6	2.1	2.7	3.5	2.1	3.2	0.3	2.5	2.7	1.0	2.0	4.0	2.0	2.0	3.3	4.1	3.3	3.5	3.7
Major Depression (MDD)	3.2	3.9	8.8	1.2	2.4	2.2	1.6	2.2	2.3	1.1	2.6	3.0	2.6	0.5	-0.5	2.7	1.4	0.8	1.7	2.1	2.1
Medication: Lisinopril	3.2	4.2	10.0	-3.2	-2.3	-2.0	-2.8	-1.8	-2.9	-2.8	-2.5	-2.3	-1.9	-0.7	0.1	-1.2	-0.7	-0.3	-1.7	-1.3	-2.6
Emphysema/chronic bronchitis	3.1	3.4	7.4	1.5	1.9	2.0	1.5	2.0	-0.4	2.1	1.8	-0.8	1.7	1.6	0.9	2.2	2.0	2.7	2.1	2.4	2.1
Had major operations	3.0	3.5	5.8	2.0	1.5	1.8	1.4	1.4	0.6	2.2	2.0	1.7	1.6	2.4	0.6	2.1	2.4	2.4	2.1	1.9	2.2
Smoking status: Previous	3.0	4.5	8.9	1.9	1.9	2.4	1.8	1.4	-0.2	2.3	2.1	-0.5	2.0	2.4	1.4	2.8	3.0	3.0	2.6	1.9	2.6
HDL Cholesterol	2.9	4.9	14.1	1.4	0.8	2.0	1.3	1.7	-0.9	0.7	1.6	-0.2	1.3	3.5	1.6	2.5	3.4	3.8	3.2	3.0	2.3
Body mass index (BMI)	2.9	12.4	24.7	-3.7	-1.9	-3.0	-2.3	-4.0	-0.0	-3.5	-2.9	1.2	-2.9	-5.0	-0.6	-4.5	-4.7	-4.8	-4.9	-4.2	-3.6
Serious illness, injury or assault to yourself	2.7	3.3	6.1	1.7	1.7	1.9	2.0	1.3	0.4	1.8	2.0	2.0	1.4	1.7	0.8	1.9	1.8	2.2	1.7	2.5	2.3
Qualifications: O levels/GCSEs or equivalent	2.7	4.4	10.6	-2.1	-3.3	-2.4	-2.5	-2.1	-1.4	-2.4	-2.8	-1.7	-2.8	0.5	0.0	-2.4	-0.9	-0.7	-1.8	-2.5	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.2	8.7	-1.3	-1.6	-1.5	-1.5	-1.0	1.7	-1.5	-1.8	-1.6	-1.1	-1.9	-1.7	-1.2	-3.0	-2.8	-1.5	-2.3	-2.2
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	5.9	-1.5	-2.1	-1.7	-2.2	-1.4	-1.1	-1.0	-2.1	-0.5	-2.3	-0.8	0.1	-1.7	-1.7	-1.0	-1.4	-2.1	-2.4
Blood clot in the leg (DVT)	2.5	3.3	9.3	-1.8	-1.6	-1.3	-1.7	-2.9	-0.2	-1.7	-1.9	-1.4	-1.4	-0.6	1.3	-3.1	-1.4	-2.0	-1.8	-2.4	-1.6
Risk taking	2.4	3.5	9.7	2.4	2.3	2.2	2.8	0.8	3.1	1.4	2.7	1.9	2.1	0.1	1.7	-0.5	0.4	-0.8	1.3	0.8	2.3
Bipolar Disorder (2018)	2.3	3.7	8.6	2.6	2.2	2.0	2.3	1.3	2.9	2.3	2.7	1.6	2.8	0.3	-0.1	1.1	1.2	-0.3	1.8	0.4	2.3
Impedance of arm (right)	2.3	10.9	36.4	2.8	1.4	2.5	1.5	2.7	-0.7	2.1	2.4	-1.4	2.0	6.0	1.4	3.1	5.0	5.6	4.2	4.3	3.9
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	8.5	-1.7	-1.5	-1.2	-1.6	-2.7	-0.0	-1.6	-1.8	-1.3	-1.1	-0.6	1.4	-2.9	-1.4	-2.0	-1.7	-2.5	-1.6
Leg fat-free mass (left)	2.2	11.6	25.9	-3.9	-2.0	-3.1	-2.2	-3.6	-0.5	-3.7	-3.1	-0.0	-3.1	-4.7	-0.7	-3.9	-4.0	-4.2	-5.1	-4.5	-3.2
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	7.6	1.1	1.0	1.9	0.7	0.3	-0.1	1.1	0.9	0.5	1.0	2.8	0.8	1.8	1.9	2.4	2.7	2.4	1.6
Ulcerative Colitis	2.1	3.0	9.4	2.2	1.5	1.6	2.0	1.9	2.2	1.1	2.1	3.1	2.1	0.2	0.7	1.8	1.0	-0.2	1.3	1.6	1.9
Leg predicted mass (left)	2.1	10.9	24.2	-3.8	-1.9	-3.0	-2.1	-3.5	-0.5	-3.6	-3.0	-0.1	-3.0	-4.6	-0.6	-3.8	-3.9	-4.1	-4.9	-4.4	-3.1
Hair/balding pattern: Pattern 2	2.1	2.7	7.5	1.5	1.6	1.7	1.0	2.4	1.4	2.0	1.4	-0.7	1.4	1.7	-0.8	2.7	1.1	2.0	1.6	1.6	1.5
Number of full brothers	2.1	2.7	6.0	1.8	2.0	2.1	1.7	1.2	1.3	1.9	1.8	2.1	2.0	0.7	0.5	2.4	0.9	0.9	1.6	1.8	1.2
Bipolar Disorder or Schizophrenia	2.0	4.9	12.9	2.5	2.4	2.8	2.3	2.0	3.6	2.3	2.8	1.8	2.7	1.6	0.3	1.6	1.3	0.3	2.7	1.8	2.4
Worry (Nagel 2018)	2.0	4.2	9.3	2.2	1.6	2.4	1.6	1.2	1.2	1.2	2.2	1.8	2.1	2.4	1.3	2.4	2.3	2.1	3.1	2.7	2.1
Alzheimer’s Disease (in father)	2.0	2.1	4.9	1.7	1.6	1.6	1.9	1.9	1.8	1.5	1.7	0.7	2.2	0.5	0.8	1.5	0.8	0.7	1.0	0.7	1.8
Nervous feelings	2.0	3.7	11.8	1.7	1.2	2.3	1.0	1.0	0.8	1.4	1.4	-0.3	1.2	3.4	0.9	1.5	1.9	2.6	3.1	3.3	1.9
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.2	6.6	1.6	2.5	2.4	2.1	2.2	1.9	1.8	2.6	2.3	1.3	0.5	0.3	0.9	0.2	0.9	1.7	2.4	1.7
Arm fat mass (right)	2.0	8.4	18.1	-3.4	-1.6	-2.5	-1.9	-3.4	-0.1	-3.3	-2.5	1.1	-2.8	-3.6	-0.5	-3.9	-3.6	-3.6	-4.2	-3.2	-2.6
Supplements: Vitamin C	2.0	2.3	7.1	1.2	1.7	1.6	1.7	2.7	1.7	1.3	1.7	0.6	1.3	1.4	-0.4	1.7	1.0	1.4	1.5	1.1	2.0
Leg fat-free mass (right)	2.0	10.4	21.8	-3.6	-2.0	-2.9	-2.0	-3.5	-0.5	-3.3	-3.0	0.2	-2.8	-4.6	-0.3	-3.9	-3.8	-4.2	-4.7	-4.3	-3.1
Arm fat mass (left)	2.0	8.3	17.6	-3.2	-1.6	-2.5	-1.8	-3.4	0.0	-3.3	-2.4	0.9	-2.6	-3.7	-0.5	-3.9	-3.7	-3.7	-4.2	-3.2	-2.6
Supplements: Calcium	2.0	2.2	7.6	0.9	1.5	1.2	1.8	2.8	-1.0	1.3	1.3	-1.5	1.2	0.5	1.3	1.9	1.6	1.9	0.6	1.1	1.6
Arm fat percentage (right)	1.9	7.7	16.3	-3.2	-1.9	-2.6	-2.1	-3.4	-0.3	-3.4	-2.5	0.7	-2.7	-2.9	-0.2	-4.0	-3.2	-3.2	-4.0	-3.0	-2.5
Mouth/teeth dental problems: Bleeding gums	1.9	2.5	7.8	1.5	2.3	1.9	2.8	1.3	0.4	1.2	2.2	0.3	2.3	-0.4	2.1	0.1	1.0	0.1	0.6	1.5	2.1
Leg predicted mass (right)	1.9	10.4	21.8	-3.6	-2.0	-2.9	-2.0	-3.5	-0.5	-3.4	-2.9	0.1	-2.8	-4.5	-0.3	-3.9	-3.8	-4.2	-4.7	-4.3	-3.1
Number of treatments/medications taken	1.8	3.3	6.1	2.0	2.3	2.5	1.7	1.3	2.0	1.5	1.9	2.0	2.1	1.9	0.3	1.5	1.4	1.1	2.1	1.7	2.1
Alcohol intake frequency.	1.8	4.2	10.2	1.8	3.2	2.4	1.9	1.5	2.2	2.7	2.8	1.8	2.1	1.3	-0.7	1.4	0.7	1.5	1.9	2.8	2.1
Number of operations (self-reported)	1.8	2.6	6.1	2.1	1.5	1.8	2.1	1.2	1.5	1.6	2.5	1.6	1.7	0.8	0.2	1.8	1.4	0.9	1.8	1.7	1.6
Diastolic blood pressure, automated reading	1.8	5.7	10.4	-1.9	-2.6	-3.0	-2.1	-2.1	-0.7	-3.0	-2.4	0.7	-2.4	-2.4	-0.3	-3.2	-2.7	-2.8	-2.9	-2.5	-2.6
Chronic bronchitis/emphysema (father)	1.7	1.9	7.9	-0.9	-0.9	-0.8	-1.0	-1.1	1.4	-1.2	-1.1	-0.6	-1.5	-0.8	-0.5	-2.8	-2.2	-2.2	-1.2	-1.4	-1.1
Waist circumference	1.7	6.3	14.2	-2.8	-1.1	-2.1	-1.6	-2.8	-0.0	-2.7	-1.9	2.0	-2.5	-3.3	-0.6	-3.6	-3.4	-3.0	-3.8	-2.2	-2.2
Type 2 Diabetes (T2D) (2012)	1.6	1.8	6.4	-1.0	-0.2	-0.5	-0.5	-1.1	1.6	-0.6	-0.7	2.5	0.2	-2.0	-1.0	0.1	-2.2	-2.2	-1.0	-1.6	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	7.5	2.6	1.9	2.0	2.1	1.6	2.0	2.7	2.3	2.4	2.7	-0.1	0.7	2.2	1.0	0.2	1.8	1.1	1.8
Past tobacco smoking	1.6	3.0	7.9	-1.6	-1.4	-1.7	-1.2	-0.7	0.5	-2.3	-1.3	0.9	-1.3	-2.2	-0.7	-2.1	-2.5	-2.8	-1.9	-1.3	-2.1
Happiness	1.6	1.9	4.4	-2.1	-1.1	-1.4	-1.4	-1.6	0.0	-1.9	-1.2	-0.5	-0.9	-1.4	-1.2	0.3	-1.7	-1.2	-1.5	-1.7	-1.8
Leg fat mass (right)	1.6	6.3	14.4	-3.1	-1.3	-2.2	-1.7	-2.7	-0.0	-2.9	-2.1	0.9	-2.7	-3.0	-1.0	-3.4	-3.3	-3.0	-3.8	-2.4	-2.2
Number of full sisters	1.6	1.9	4.0	-1.7	-0.8	-1.0	-1.4	-1.0	-2.0	-1.4	-1.9	-2.0	-0.9	-1.3	0.8	-1.1	-0.6	-0.8	-1.7	-2.0	-1.6
Arm fat percentage (left)	1.6	6.2	14.0	-2.9	-1.5	-2.3	-1.7	-3.2	-0.2	-3.1	-2.1	0.9	-2.2	-2.8	-0.2	-3.6	-2.9	-3.0	-3.7	-2.6	-2.2
Heart attack/myocardial infarction (self-reported)	1.6	2.1	7.7	0.7	1.5	2.4	1.5	0.5	0.3	0.6	1.2	1.3	0.7	1.7	2.8	-0.1	1.4	1.4	1.7	1.0	1.9
Ovarian Cancer	1.5	2.0	4.3	1.1	1.3	1.6	0.9	2.1	-0.1	1.6	1.0	-0.0	1.0	1.9	1.0	0.6	2.0	1.6	1.7	1.7	1.6
Coronary Artery Disease (CAD)	1.5	1.7	4.5	0.2	2.1	1.4	1.4	2.0	2.1	0.8	1.6	1.7	1.4	-0.1	-0.6	1.4	-0.1	0.1	0.5	1.2	1.6
Weight	1.5	7.4	15.3	-3.2	-1.3	-2.1	-1.6	-3.0	0.1	-2.8	-2.4	0.9	-2.8	-3.6	-0.6	-3.8	-3.6	-3.5	-3.9	-3.0	-2.3
Medication for pain relief, constipation, heartburn	1.5	2.5	5.2	-1.1	-1.9	-2.3	-1.1	-1.0	-1.2	-1.5	-1.6	-1.8	-1.2	-2.2	0.2	-0.9	-1.3	-1.5	-2.3	-2.0	-1.8
Suffer from ‘nerves’	1.5	2.4	7.9	1.2	1.1	2.4	1.2	0.6	0.8	0.5	1.5	-0.0	1.4	1.9	1.8	1.3	1.5	1.3	2.8	2.2	1.4
Whole body fat-free mass	1.5	8.5	20.3	-3.4	-1.4	-2.4	-1.6	-2.5	0.3	-2.8	-2.5	0.4	-2.7	-4.5	-1.2	-3.2	-4.0	-4.0	-4.3	-3.8	-2.7
Whole body water mass	1.5	8.6	20.4	-3.4	-1.4	-2.4	-1.6	-2.5	0.4	-2.8	-2.5	0.4	-2.7	-4.5	-1.2	-3.3	-4.1	-4.1	-4.3	-3.8	-2.8
Ever taken oral contraceptive pill	1.5	1.6	4.6	-1.0	-2.1	-1.8	-1.6	-0.5	-0.7	-1.2	-2.0	-1.3	-1.5	-0.4	-0.9	-0.1	-1.1	-0.8	-1.0	-1.2	-1.7
Basal metabolic rate	1.5	8.4	18.6	-3.4	-1.4	-2.4	-1.6	-2.6	0.2	-2.9	-2.5	0.5	-2.8	-4.3	-1.1	-3.4	-3.9	-3.9	-4.3	-3.6	-2.6
Arm fat-free mass (left)	1.5	7.6	16.9	-3.1	-1.3	-2.3	-1.5	-2.1	0.5	-2.4	-2.4	0.5	-2.9	-4.1	-1.6	-3.2	-4.0	-3.8	-3.9	-3.3	-2.6
Basal cell carcinoma (self-reported)	1.5	1.8	4.3	-0.9	-1.5	-1.7	-1.3	-0.8	-0.7	-0.2	-1.6	-0.7	-1.8	-1.6	-2.1	-0.3	-1.9	-1.1	-1.0	-0.6	-2.1
Leg fat mass (left)	1.5	6.0	13.2	-2.8	-1.3	-2.1	-1.6	-2.6	0.1	-2.7	-2.0	1.2	-2.6	-3.1	-0.8	-3.5	-3.3	-3.1	-3.6	-2.3	-2.1
Fasting Glucose	1.4	1.7	3.2	-0.9	-0.7	-1.3	-1.0	-1.7	0.2	-0.8	-1.0	0.6	-0.9	-1.8	-1.2	-1.0	-1.7	-1.8	-1.8	-1.8	-1.7
Townsend deprivation index at recruitment	1.4	1.9	4.2	1.3	1.6	1.8	1.0	0.2	1.1	1.8	1.0	-0.8	1.2	1.5	-0.4	1.4	0.9	1.7	2.0	2.0	1.4
Supplements: Glucosamine	1.4	1.8	6.1	1.6	0.6	-0.5	1.3	1.0	1.4	1.0	1.2	2.1	2.1	-2.5	-0.6	1.3	-0.3	-1.9	-0.8	-1.1	-0.0
Heart attack	1.4	1.8	6.4	0.5	1.4	2.2	1.4	0.5	0.1	0.6	1.1	1.1	0.6	1.6	2.5	0.0	1.4	1.4	1.5	1.0	1.9
Pulse wave peak to peak time	1.4	1.7	3.9	-1.2	-1.5	-1.4	-1.7	-1.5	-0.1	-1.3	-1.5	0.4	-0.8	-1.1	-0.7	-0.8	-1.1	-1.6	-1.2	-2.0	-1.7
Chest pain or discomfort	1.4	2.1	4.6	1.2	1.7	2.2	1.5	1.0	1.3	1.1	1.6	0.4	0.9	1.8	0.6	0.2	1.1	1.5	2.0	1.9	2.0
Commuting to job workplace: Public transport	1.4	1.6	6.1	-0.9	-2.5	-1.0	-1.9	-1.0	0.0	-1.0	-2.0	-1.4	-1.8	2.1	-0.3	-0.9	-0.2	0.3	0.8	-0.3	-0.6
Supplements: Fish oil (including cod liver oil)	1.4	1.8	8.2	1.7	1.2	0.1	1.6	2.9	0.7	1.2	1.6	0.6	2.0	-0.9	-1.5	2.1	0.5	0.0	0.1	0.4	0.9
Arm predicted mass (left)	1.4	7.1	18.7	-2.7	-1.0	-2.2	-1.3	-2.2	0.7	-2.1	-2.1	0.8	-2.5	-4.3	-1.6	-3.0	-4.1	-3.8	-3.8	-3.0	-2.5
Hand grip strength (left)	1.3	3.6	14.4	-1.1	-1.3	-1.3	-0.9	-0.7	0.6	-0.7	-1.4	-0.3	-1.6	-3.5	-0.2	-1.9	-2.4	-3.8	-1.9	-2.9	-2.1
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	5.2	-0.4	0.1	-1.1	-0.1	0.1	0.6	-1.3	0.2	0.8	0.6	-2.3	-0.6	-1.0	-1.4	-2.1	-2.3	-1.4	-1.1
Pulse wave Arterial Stiffness index	1.3	1.6	4.0	1.0	1.2	1.3	1.5	1.4	0.0	1.2	1.3	-0.6	0.6	1.3	0.6	0.7	1.2	1.8	1.3	2.0	1.7
Medication: Amlodipine	1.3	1.8	3.4	1.5	1.5	1.6	1.4	0.7	1.5	1.4	1.5	1.5	1.2	1.3	0.1	1.0	1.0	0.9	1.5	1.8	1.8
Birth weight	1.3	2.8	6.6	1.5	1.9	2.0	1.9	1.7	-0.6	1.5	1.7	-0.0	1.3	1.3	1.9	0.8	2.2	1.9	1.4	1.8	2.6
Qualifications: nursing, teaching	1.3	2.1	4.6	-1.8	-2.1	-1.4	-1.9	-1.3	-0.8	-1.6	-1.9	-1.0	-1.9	-0.4	-0.3	-1.5	-0.9	-1.1	-1.0	-1.8	-1.6
Mouth/teeth dental problems	1.2	1.9	4.7	-1.0	-1.4	-1.9	-1.5	-0.4	-0.1	-0.7	-1.5	-2.0	-1.3	-1.0	-2.2	0.4	-1.3	-0.8	-1.5	-1.9	-1.7
Pain all over the body in last month	1.2	1.3	3.5	1.2	1.9	0.9	1.1	1.1	0.9	1.8	1.4	1.2	1.3	-0.0	-1.1	0.9	-0.1	0.7	0.7	1.3	0.9
Hair/balding pattern: Pattern 3	1.2	1.7	5.1	-0.7	-1.3	-1.8	-0.9	-1.4	-1.7	-1.1	-1.4	0.2	-0.5	-2.3	-0.0	-0.8	-0.6	-1.4	-1.6	-1.7	-1.5
Medication: Lansoprazole	1.2	1.4	5.4	-1.9	-0.7	-1.1	-1.3	-2.3	-1.1	-1.6	-0.8	-0.4	-1.1	-0.3	-0.4	-1.6	-1.1	-0.4	-1.2	-0.6	-0.9
Neck or shoulder pain in last month	1.2	1.7	5.2	-0.4	1.5	2.1	0.4	1.2	-0.3	0.3	1.0	1.3	0.2	2.3	1.5	0.1	1.3	2.3	1.3	1.0	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	9.7	0.3	0.1	0.4	0.3	1.9	0.8	1.2	0.4	-3.1	0.5	0.7	-0.5	1.9	0.2	0.9	1.1	1.6	0.7
Whole body fat mass	1.2	4.9	12.4	-2.6	-0.9	-1.8	-1.2	-2.6	-0.1	-2.6	-1.7	0.9	-2.1	-2.9	-0.2	-3.5	-2.7	-2.7	-3.5	-2.2	-1.6
Breast cancer (self-reported)	1.2	1.4	4.7	-1.2	-1.0	-1.8	-0.8	-0.4	-1.1	-1.4	-1.1	-0.3	-0.3	-1.4	-0.8	-0.7	-0.8	-1.1	-2.2	-2.0	-1.2
Osteoporosis (self-reported)	1.2	1.5	4.6	-1.0	-1.9	-1.2	-1.2	-1.5	-0.3	-1.4	-1.6	-1.4	-0.8	0.6	0.9	-1.4	-0.2	-1.0	-0.9	-2.1	-1.0
HbA1C	1.1	1.2	4.7	-0.5	0.1	-1.1	-0.5	0.3	0.9	-0.3	-0.4	-0.7	0.7	-2.2	-1.1	0.3	-0.7	-1.6	-1.8	-1.9	-0.9
Diabetes (father)	1.1	1.4	3.0	1.1	1.7	0.7	1.6	0.2	1.2	1.6	1.6	1.6	1.7	-0.9	-0.8	1.5	0.1	-0.2	-0.6	0.8	1.0
Trunk fat-free mass	1.1	6.3	16.0	-2.9	-1.0	-2.0	-1.2	-1.8	0.6	-2.2	-2.1	0.4	-2.4	-4.0	-1.6	-2.5	-3.7	-3.5	-3.6	-3.2	-2.3
Trunk predicted mass	1.1	6.1	15.8	-2.9	-1.0	-2.0	-1.2	-1.8	0.6	-2.1	-2.1	0.4	-2.3	-4.0	-1.7	-2.4	-3.7	-3.4	-3.6	-3.1	-2.2
Ever highly irritable/argumentative for 2 days	1.1	1.3	4.7	0.6	1.2	1.4	0.5	0.5	2.2	0.7	0.9	0.7	1.2	1.6	-0.7	1.4	0.3	0.6	1.6	1.5	1.0
Medication: Blood pressure	1.1	2.0	5.1	0.5	2.2	2.2	1.4	1.1	1.8	0.9	1.5	1.8	1.5	0.9	0.5	0.9	0.7	0.5	1.6	1.5	2.0
Arm predicted mass (right)	1.1	5.9	18.7	-2.5	-0.7	-1.9	-0.8	-1.7	0.6	-1.9	-1.7	0.8	-2.0	-4.3	-1.5	-2.6	-3.6	-3.7	-3.7	-2.8	-2.2
Leg pain on walking	1.1	1.4	3.6	1.7	1.6	1.2	1.5	1.9	0.9	1.3	1.7	1.3	1.4	-0.3	0.3	1.1	0.3	0.3	0.4	0.9	0.7
Ulcerative Colitis (UC)	1.0	1.9	8.6	1.7	1.1	0.6	1.9	2.0	1.3	0.3	1.8	2.9	1.8	-0.9	0.4	1.2	0.5	-0.9	0.2	0.9	1.2
Blood Platelet Count	1.0	11.4	31.6	1.8	2.3	4.3	1.7	3.2	-0.7	2.4	2.2	-0.0	1.1	5.6	2.5	2.7	4.3	5.5	5.3	4.3	3.5
Medication for hormone replacement therapy	1.0	1.1	3.3	-1.0	-0.2	-0.7	-0.9	-0.4	1.2	-0.8	-0.7	0.2	-0.5	-0.9	-1.0	-1.0	-1.5	-1.8	-1.2	-1.7	-1.2
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	4.7	0.9	0.9	0.7	1.3	0.9	2.0	1.0	1.0	-2.2	0.5	0.9	-1.5	1.5	0.3	0.6	0.5	0.6	1.0
Medication: Ramipril	1.0	1.3	3.5	1.5	1.1	1.2	1.1	0.9	1.4	0.8	1.2	1.9	1.5	1.0	0.8	0.5	1.0	0.5	0.9	0.2	1.5
Hip circumference	1.0	4.3	9.1	-2.5	-1.2	-1.8	-1.6	-2.6	-0.3	-2.2	-2.0	1.4	-2.4	-2.1	-0.4	-2.9	-2.3	-2.0	-3.0	-2.5	-1.7
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.1	-1.4	-1.1	-1.3	-1.1	-1.1	-0.9	-1.4	-1.2	-0.0	-0.8	-0.6	-0.2	-0.5	-0.7	-0.4	-1.7	-1.8	-1.3
Arm fat-free mass (right)	1.0	5.1	17.1	-2.2	-0.5	-1.6	-0.7	-1.6	0.9	-1.6	-1.5	1.0	-1.8	-4.1	-1.3	-2.5	-3.5	-3.6	-3.4	-2.5	-1.9
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	5.9	0.5	1.0	1.6	0.9	1.2	1.1	0.4	1.2	0.7	0.5	2.4	0.3	0.7	1.2	1.5	1.5	2.2	1.7
Mineral and other dietary supplements	1.0	1.3	6.3	-1.6	-0.6	0.4	-1.4	-2.5	0.0	-0.8	-1.2	-0.1	-2.0	1.3	0.5	-1.8	-0.9	0.2	0.4	0.4	-0.6
Mother’s age at death	1.0	1.3	4.5	1.1	0.9	1.1	0.6	0.7	2.1	1.2	1.0	1.7	1.1	0.5	-0.8	1.2	-0.1	0.1	1.6	1.3	0.9
Irritability	1.0	1.7	6.3	-2.2	-1.2	-0.8	-1.8	-2.5	-0.5	-1.7	-1.6	0.4	-1.8	0.3	-0.5	-1.6	-1.0	-0.4	-0.6	-0.1	-1.0
Age started oral contraceptive pill	1.0	1.3	3.8	-1.0	-1.4	-1.0	-1.4	-0.5	-0.9	-1.1	-1.4	-1.9	-1.7	0.5	-0.3	-1.9	-0.9	-0.1	-0.3	-0.5	-0.9
Schizophrenia (2018)	0.9	2.0	5.0	1.1	1.2	2.0	1.1	1.4	2.2	1.0	1.3	1.2	1.3	1.8	0.4	1.1	0.7	0.6	2.1	1.7	1.3
Average weekly spirits intake	0.9	1.1	4.6	-1.2	-1.5	-1.1	-1.3	-1.3	-2.1	-1.2	-1.3	-1.0	-0.8	0.1	0.0	0.0	0.5	0.5	-0.6	0.5	-1.0
Relative age voice broke	0.9	1.4	5.7	1.3	0.0	0.0	0.6	1.4	1.2	1.3	0.7	0.6	0.6	1.0	-1.8	2.4	0.2	1.0	1.2	1.9	0.5
Medication: Atenolol	0.9	1.1	3.1	0.7	1.7	1.8	1.4	0.2	0.5	0.4	1.5	0.8	1.5	-0.4	1.6	0.6	0.7	-0.1	0.8	0.1	1.1
Lung cancer (father)	0.9	1.1	4.1	-1.0	-0.5	-1.2	-1.0	-0.9	-0.1	-0.7	-0.8	0.6	-0.5	-0.8	-0.1	-1.4	-1.4	-1.2	-2.0	-1.4	-1.2
Leg fat percentage (right)	0.9	3.2	7.2	-2.2	-0.7	-1.5	-1.2	-1.5	0.2	-2.0	-1.3	1.0	-2.1	-2.1	-1.1	-2.4	-2.7	-2.0	-2.7	-1.3	-1.6
Medication: Bendroflumethiazide	0.9	1.3	4.7	-1.7	-0.5	-0.3	-0.6	-1.5	-0.7	-2.2	-0.9	0.3	-1.2	-0.5	1.3	-1.9	-0.6	-0.9	-1.3	-1.3	-0.3
Alcohol drinker status: Previous	0.9	1.1	2.7	1.1	1.3	1.2	1.1	0.3	1.0	1.4	1.1	-0.2	1.6	0.0	-0.0	1.3	0.7	0.1	1.3	1.6	0.7
Breast Cancer	0.8	1.9	5.3	-0.7	-1.4	-1.3	-1.6	-2.2	0.3	-1.0	-1.6	-1.3	-0.8	-0.5	-0.7	-2.3	-1.7	-1.7	-1.0	-1.7	-1.3
Age at First Birth	0.8	1.1	4.5	0.7	0.6	1.4	0.1	1.3	1.0	1.1	0.3	0.5	-0.0	2.1	0.1	0.9	0.7	1.1	1.9	1.5	0.8
Hypothyroidism (self reported)	0.8	1.7	5.4	-0.5	-1.0	-1.9	-0.8	-1.0	-1.7	-0.9	-1.1	0.5	-0.8	-1.6	0.1	-2.3	-0.7	-1.3	-2.2	-1.7	-1.1
Relative age of first facial hair	0.8	1.6	6.2	1.4	0.4	1.3	0.7	0.7	1.4	1.4	0.9	0.0	0.7	1.9	0.1	1.7	0.9	1.3	2.5	1.7	1.0
Ever had hysterectomy (womb removed)	0.8	0.9	3.4	0.8	-0.3	-0.1	-0.2	1.1	-1.2	0.4	-0.0	-0.1	0.3	1.4	-0.8	1.3	1.6	1.8	0.9	0.7	0.3
Severe depression (siblings)	0.8	0.9	3.4	0.4	1.6	1.8	1.1	0.5	0.6	0.6	1.2	-0.2	1.4	-0.7	1.1	0.9	0.7	-0.2	1.0	-0.1	0.7
Pack years adult smoking proportion	0.8	1.1	3.8	1.5	1.0	1.7	1.0	-0.5	1.3	1.3	1.2	0.4	1.0	0.5	0.8	-0.1	0.2	-0.3	1.9	1.4	0.8
Average weekly fortified wine intake	0.8	0.9	7.8	-0.6	-0.4	-0.9	-0.4	-0.4	1.6	-0.1	-0.5	-0.3	-0.8	-0.0	-2.8	0.2	-1.6	-0.5	-0.9	0.0	-0.1
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.1	-0.4	-1.2	-0.8	-1.3	-0.8	0.5	-1.5	-1.3	-0.7	-0.4	-0.2	0.1	-1.2	-0.8	-1.1	-0.5	-1.4	-1.2
Number of incorrect matches in round	0.8	1.3	5.1	0.6	1.3	-0.4	1.5	-1.0	0.4	-0.3	1.2	2.2	1.5	-1.9	-0.2	0.4	-0.1	-0.9	-1.6	0.7	0.8
Qualifications: A levels/AS levels or equivalent	0.8	1.9	5.4	-1.3	-2.1	-1.9	-1.0	-0.4	0.6	-1.8	-1.4	0.9	-1.0	-0.3	-1.0	-1.1	-0.9	-1.6	-1.9	-2.3	-1.1
Peak expiratory flow (PEF)	0.8	1.8	6.4	-0.5	-1.4	-0.5	-0.9	0.6	-0.9	0.4	-1.1	-1.0	-1.6	2.5	-1.5	1.8	1.1	2.5	1.2	1.2	0.1
Glaucoma (self-reported)	0.8	0.9	2.3	1.1	1.1	0.9	1.5	1.0	0.8	0.8	1.2	0.7	0.9	0.5	0.5	0.6	0.7	0.3	0.6	1.2	1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	6.2	-0.9	-0.2	-1.4	-0.9	-0.7	-0.5	-0.9	-0.8	0.6	-1.0	-1.4	-0.7	-1.9	-1.2	-1.2	-2.5	-1.8	-1.0
Eye problems/disorders: None of the above	0.8	0.9	3.0	-0.9	-0.5	-0.4	-1.3	-1.1	-1.7	0.2	-1.2	-1.7	-0.8	-0.5	0.2	-0.7	-0.1	0.0	-0.2	-1.1	-1.4
Medication: Allopurinol	0.8	1.0	4.6	-0.8	-1.1	-0.3	-0.3	-1.2	-0.9	-0.8	-0.8	1.2	-0.9	-0.4	1.6	-2.1	-0.2	-1.4	0.0	-0.8	-0.8
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.6	1.0	1.7	0.8	1.3	0.5	-0.2	1.4	1.3	1.2	0.9	-1.9	0.4	0.1	-0.1	-0.5	-0.2	0.1	0.3
Medication: Aspirin	0.8	1.1	3.0	0.9	1.2	1.7	0.5	0.7	0.4	1.5	0.7	0.8	0.6	1.5	0.8	0.3	1.0	1.2	1.6	0.9	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	4.0	0.8	0.4	0.6	0.7	0.1	0.8	0.7	0.8	1.4	1.1	1.0	-0.7	2.0	0.7	0.7	1.2	1.6	0.7
Commuting to job workplace: Walk	0.8	0.8	3.6	-0.3	-0.7	-0.0	-0.8	-0.4	1.9	-0.1	-0.8	-1.6	0.1	0.5	-1.6	1.3	-1.0	-0.5	0.7	-0.6	-0.6
Medication: Aspirin	0.8	1.0	3.1	0.7	1.0	1.8	0.4	0.3	-0.2	1.3	0.5	0.7	0.5	1.4	1.7	-0.2	1.0	1.2	1.6	0.6	0.9
Wears glasses or contact lenses	0.8	0.9	2.1	0.6	1.0	1.0	0.6	0.6	1.0	0.9	0.8	1.1	0.9	1.1	-0.7	1.5	0.7	1.2	1.0	1.2	1.1
High cholesterol (Self-reported)	0.8	1.4	3.8	1.7	0.7	0.6	1.2	1.0	0.7	1.5	1.2	1.9	1.1	0.2	-0.8	1.8	0.4	0.6	1.1	1.6	1.0
Medication: Paracetamol	0.8	1.2	5.5	1.2	0.4	1.1	0.8	0.5	2.3	0.6	0.9	1.8	0.5	1.1	-0.5	-0.3	-0.3	-0.5	1.8	1.5	0.8
Alcohol drinker status: Never	0.8	1.0	3.4	0.3	0.7	1.3	0.2	0.1	0.5	0.1	0.7	0.8	0.4	1.8	0.1	0.6	1.0	1.2	1.9	1.8	1.1
Leg fat percentage (left)	0.8	2.9	6.7	-1.8	-0.7	-1.4	-1.0	-1.5	0.3	-1.6	-1.1	1.3	-1.9	-2.3	-0.8	-2.5	-2.6	-2.1	-2.5	-1.1	-1.5
Neuroticism (Nagel 2018)	0.7	1.5	3.4	0.6	0.9	1.4	1.2	0.6	1.0	-0.2	1.4	1.7	1.0	1.2	0.8	1.7	1.1	1.2	1.6	1.9	1.5
Sensitivity / hurt feelings	0.7	1.1	3.0	-0.2	0.8	1.5	0.5	1.7	1.6	-0.2	0.9	0.9	0.4	1.3	0.0	1.7	0.3	1.0	1.5	1.1	0.8
Medication: Co-codamol	0.7	0.8	2.6	0.2	1.1	1.6	0.6	0.4	0.4	0.1	0.8	-1.3	0.7	0.9	0.7	1.1	0.8	1.0	1.4	0.9	0.6
Trunk fat mass	0.7	2.8	9.4	-2.0	-0.6	-1.3	-0.9	-2.1	0.0	-2.1	-1.3	0.7	-1.9	-1.8	-0.1	-3.1	-2.0	-1.8	-2.7	-1.2	-0.9
Fluid intelligence score	0.7	1.5	5.2	-1.1	-1.7	-0.0	-1.5	-0.1	-1.3	-1.0	-1.4	-1.6	-1.3	2.3	1.4	-0.6	1.0	1.5	0.9	0.4	-0.1
Pulse rate	0.7	1.2	4.2	1.0	0.4	0.7	0.8	-0.1	0.8	0.8	0.7	1.0	-0.3	1.7	-1.1	0.9	0.6	1.4	1.7	2.1	1.1
Medication: Paracetamol	0.7	1.2	3.4	0.8	0.7	1.1	1.1	1.2	1.9	0.3	1.3	1.9	0.3	1.6	-0.3	-0.4	0.2	0.2	1.2	1.6	1.2
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	3.3	-0.9	-1.2	-1.3	-1.0	-0.5	-1.4	-0.9	-0.9	-1.2	-1.0	-1.4	-0.0	-0.7	-0.8	-0.7	-1.2	-1.2	-1.8
Number of children fathered	0.7	0.7	4.5	-0.3	0.7	0.4	0.2	0.6	2.1	0.1	0.4	1.8	0.4	-0.6	-1.2	0.2	-1.1	-0.8	-0.1	-0.1	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.3	0.3	-0.1	-0.9	0.1	-0.1	0.8	0.4	-0.0	-1.4	-0.1	-1.5	-1.8	0.1	-1.1	-1.3	-1.2	-0.8	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.9	-0.0	0.2	0.1	0.6	0.4	-1.7	-0.6	0.6	-0.9	0.1	1.0	1.6	-0.6	1.6	1.4	-0.3	0.7	1.0
Mood swings	0.7	1.2	4.6	0.0	1.1	1.6	0.9	0.1	1.1	0.0	1.3	0.7	0.6	1.4	0.6	0.7	0.6	1.1	1.5	2.1	1.2
Loneliness, isolation	0.7	1.0	2.9	-1.3	-0.4	-0.3	-0.2	-0.9	0.2	-1.4	-0.4	-0.6	-1.1	-1.7	0.4	-1.1	-1.5	-1.4	-0.6	-0.9	-1.0
Friendships satisfaction	0.7	0.9	2.3	-1.2	-0.7	-0.6	-0.4	-0.0	0.8	-1.4	-0.6	0.9	-0.0	-1.1	0.2	-0.5	-1.4	-1.5	-0.9	-1.5	-1.0
Eye problems/disorders: Cataract	0.7	0.8	2.7	-1.1	-1.6	-1.4	-1.1	-0.2	-0.8	-1.3	-1.1	-0.1	-1.1	0.5	-0.6	-0.1	-0.4	0.4	-0.6	0.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.7	-1.6	-1.6	-1.4	-0.7	-0.9	-2.2	-1.6	-1.1	-0.8	-1.3	1.2	-0.6	0.8	0.4	1.7	-0.5	0.4	-0.3
Mean Putamen Volume	0.6	0.7	4.2	0.3	0.4	0.2	0.5	-1.3	-0.3	0.2	0.3	2.1	0.3	-1.6	0.9	-0.3	-0.3	-1.1	-0.2	-0.8	-0.6
Hearing difficulty/problems: Yes	0.6	0.9	3.8	-1.2	-0.2	-0.3	-0.7	-0.7	1.2	-0.9	-0.6	-0.7	-0.9	-0.4	-1.4	-0.3	-1.9	-0.7	-0.7	-0.9	-1.0
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.9	0.9	0.8	1.0	0.4	1.2	1.4	1.0	0.8	-0.1	0.3	0.8	-0.8	0.1	-0.3	0.1	1.5	1.7	0.4
Angina	0.6	0.8	2.8	-0.1	0.9	1.4	0.3	0.8	-0.0	0.3	0.6	-0.2	0.4	1.7	1.2	-0.0	1.0	1.3	1.1	0.9	1.0
Medication: Metformin	0.6	0.8	5.3	0.2	0.6	0.5	0.6	0.6	2.3	-0.3	0.6	0.7	0.4	-0.6	0.5	-1.3	-0.7	-1.8	-0.8	-0.7	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.6	1.7	1.0	0.8	1.3	0.9	1.5	1.9	1.3	1.8	1.7	-0.7	0.2	0.9	0.1	-0.3	0.8	0.7	1.2
Allergy	0.6	1.5	6.9	1.0	0.4	1.3	0.9	0.3	1.6	0.7	1.1	2.6	0.6	0.7	-0.0	1.3	0.1	0.1	2.2	1.9	0.7
Time employed in main current job	0.6	0.6	2.6	-1.4	0.1	0.8	-0.7	0.4	-0.5	-0.8	-0.4	-1.6	-0.9	1.3	0.9	-0.9	-0.0	0.7	0.2	0.3	0.1
Illnesses of mother	0.6	0.8	3.5	0.4	0.6	-0.0	-0.2	0.1	1.0	1.4	0.3	1.1	0.3	0.7	-1.9	1.9	-0.3	1.0	-0.0	0.4	0.3
Breastfed as a baby	0.6	0.7	6.4	-0.8	-0.4	-0.9	-0.3	-0.1	-1.2	-0.1	-0.6	-2.5	-0.7	-0.2	-0.7	-0.1	-0.4	0.5	-1.0	-0.6	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.0	1.0	0.7	1.2	1.0	0.6	1.4	0.5	1.1	1.3	0.9	0.1	0.8	0.7	0.2	-0.1	1.3	1.3	0.8
High blood pressure (siblings)	0.6	0.8	2.6	-1.3	-0.5	-0.3	-0.8	-0.3	0.1	-1.6	-0.6	1.0	-0.4	-0.8	0.6	-1.3	-1.1	-1.2	-0.5	-0.1	-1.2
Body fat percentage	0.6	2.4	8.1	-1.9	-0.6	-1.2	-0.9	-1.9	-0.1	-2.0	-1.1	0.8	-1.7	-1.5	-0.0	-2.9	-1.8	-1.6	-2.5	-1.0	-0.9
Angina (self-reported)	0.6	0.8	2.4	0.2	0.9	1.5	0.5	0.8	0.3	0.3	0.8	0.0	0.5	1.6	1.2	-0.1	1.0	1.0	1.1	0.9	1.1
Illnesses of siblings: Diabetes	0.6	0.7	1.8	0.8	0.6	0.8	1.1	0.3	0.7	0.2	0.9	1.4	1.0	0.8	0.8	0.6	0.9	0.0	0.6	1.0	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.2	0.9	1.2	1.0	1.4	1.5	-1.5	0.4	1.3	0.9	0.5	-0.3	1.6	0.2	1.8	0.9	0.5	1.0	1.2
Number of self-reported non-cancer illnesses	0.6	1.1	2.2	1.1	1.2	1.5	1.5	-0.3	0.7	0.3	1.2	1.2	1.3	0.7	1.4	0.3	1.2	0.3	1.1	0.6	1.2
Medication: Blood pressure	0.6	1.1	4.4	-0.9	-0.7	-0.5	-0.7	-1.7	-2.1	-1.7	-0.8	0.3	-0.7	-0.2	1.7	-1.8	0.2	-0.0	-0.6	-0.5	-0.8
Illnesses of father: High blood pressure	0.6	0.8	2.0	-0.7	-0.4	-0.8	-0.9	-0.3	-0.8	-0.6	-0.8	0.6	-0.4	-1.4	0.2	-1.4	-1.3	-0.9	-1.3	-0.8	-1.3
Ever smoked	0.6	1.0	3.0	1.2	0.5	0.7	0.6	0.6	0.0	1.7	0.4	-0.6	0.4	1.5	-0.0	1.0	1.4	1.7	1.0	0.4	1.3
Ever had prostate specific antigen (PSA) test	0.6	0.7	4.7	-0.1	0.3	0.4	0.4	0.8	2.2	0.4	0.4	1.5	0.1	-0.0	-1.1	-0.1	-1.3	-0.9	-0.1	0.1	0.5
Fractured/broken bones in last 5 years	0.6	0.8	2.2	1.2	0.8	0.7	0.8	1.5	1.4	1.0	1.0	0.8	1.0	0.0	-0.6	1.0	-0.1	-0.4	1.0	0.6	0.3
Ever depressed for a whole week	0.6	0.7	3.4	-0.1	1.4	0.6	0.7	1.0	0.4	0.0	0.9	-1.5	1.1	-0.3	-0.6	1.9	0.2	0.9	-0.2	0.3	0.5
Pack years of smoking	0.6	0.9	3.8	1.2	0.8	1.6	0.9	-0.5	0.9	1.1	0.9	0.4	0.8	0.5	1.1	-0.2	0.3	-0.2	2.0	1.4	0.7
Depression (Nagel 2018)	0.5	0.7	2.1	0.7	1.1	0.9	1.2	0.7	0.4	0.4	1.2	1.0	1.5	-1.0	1.3	0.6	0.4	-0.5	0.5	0.5	0.6
Irritable Bowel Disease (IBD)	0.5	1.1	4.0	1.5	1.0	0.6	1.4	1.4	1.0	0.5	1.3	2.0	1.4	-0.7	0.1	1.0	0.4	-0.5	0.4	0.3	0.8
Reaction Time	0.5	1.0	3.1	-0.6	0.3	0.7	0.4	0.8	-1.2	-0.9	0.4	-1.3	-0.5	1.8	1.1	-0.3	1.7	1.7	0.4	0.6	1.2
Neuroticism (2016)	0.5	0.7	1.9	-0.4	0.8	1.3	0.7	1.4	0.1	-0.2	0.5	-0.4	-0.1	1.1	0.4	0.8	0.4	1.4	1.0	1.1	0.8
Triglycerides	0.5	0.8	3.7	0.8	1.0	-0.2	0.7	0.2	0.4	0.8	0.8	0.8	1.4	-1.9	-0.6	1.1	-0.3	-1.0	-0.9	-0.4	-0.3
Heel T-Score	0.5	4.1	18.7	1.5	0.7	-0.1	1.2	-1.0	2.0	1.1	0.4	4.3	2.2	-4.3	0.7	0.1	-1.6	-3.9	-0.7	-1.6	-0.6
Smoking Status	0.5	1.1	3.5	0.6	1.0	1.5	0.1	-0.3	-1.4	1.1	0.3	0.3	0.7	1.1	1.9	0.4	1.7	1.4	1.4	0.8	0.7
Allergy or Eczema	0.5	1.4	5.9	-0.7	-0.7	-1.8	-0.8	-0.5	-0.4	-0.7	-1.0	-1.2	-0.5	-1.0	-1.4	-1.3	-0.9	-0.8	-2.4	-2.1	-0.8
Lung FEV1/FVC ratio	0.5	2.4	17.0	-1.0	-1.1	0.2	-1.3	0.2	-0.7	-1.0	-0.8	-0.3	-1.4	4.1	-0.9	1.0	1.8	3.0	1.2	1.7	0.6
Neuroticism	0.5	1.3	3.7	0.6	0.8	1.3	0.7	0.5	0.6	0.3	1.2	1.3	0.8	1.1	0.5	1.7	1.1	1.3	1.9	1.8	0.9
Diabetes (mother)	0.5	0.6	3.7	0.9	0.1	0.0	0.7	-0.8	0.3	0.4	0.2	0.4	0.3	-1.9	0.7	-0.6	-0.4	-1.7	-0.3	-0.5	-0.4
Hand grip strength (right)	0.5	1.4	5.4	-0.1	-1.3	-1.3	-0.4	-0.4	0.7	-0.0	-1.1	0.7	-1.2	-1.9	-1.0	-0.5	-1.4	-2.3	-1.0	-1.6	-1.2
Hayfever, allergic rhinitis or eczema	0.5	1.1	5.7	-0.7	-0.4	-1.2	-0.7	0.3	-0.9	-0.5	-0.9	-2.4	-0.4	-0.9	-0.6	-0.8	-0.4	-0.5	-1.9	-2.0	-0.7
Stomach or abdominal pain in last month	0.5	0.6	4.5	-0.2	-0.1	-0.2	-0.6	-1.1	1.5	0.1	-0.5	0.3	-0.3	0.0	-2.1	0.5	-1.3	-0.3	0.1	-0.4	-0.7
High blood pressure (mother)	0.5	0.7	3.2	-0.1	0.1	0.5	0.3	-0.1	-0.1	-1.3	-0.2	-1.0	0.4	-1.1	1.8	-1.3	0.0	-1.5	-0.0	-0.9	-0.4
Father’s age at death	0.5	0.6	2.3	0.4	-0.3	0.3	-0.2	0.0	1.1	0.3	-0.5	1.3	0.4	-0.7	0.5	-0.6	-0.9	-1.5	0.6	-1.5	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	4.0	-0.2	0.1	-0.0	-0.4	0.7	0.5	-0.0	0.4	0.1	0.2	1.4	-2.0	1.5	0.7	1.1	0.6	0.6	0.2
Gout (self-reported)	0.5	0.7	3.0	-0.8	-1.2	-0.3	-0.6	-0.9	-0.2	-0.9	-0.9	-0.1	-0.9	0.4	0.9	-1.7	-0.3	-1.1	-0.0	-1.0	-0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.5	2.4	0.4	1.0	0.7	0.8	0.1	0.2	0.3	0.9	1.6	0.4	-1.1	0.5	-1.0	-0.5	-0.7	0.1	0.9	-0.0
Heart disease (mother)	0.5	0.6	3.2	0.3	-0.3	0.2	-0.5	-0.4	-0.9	0.4	-0.2	-0.3	0.1	1.8	0.4	0.1	1.2	1.6	0.8	1.2	0.5
Family relationship satisfaction	0.5	0.7	2.7	0.0	0.1	-0.2	0.1	-0.3	1.2	-0.5	0.2	0.3	0.8	-1.6	0.2	-0.3	-1.3	-1.6	-0.7	-1.1	-0.6
Average weekly red wine intake	0.5	0.8	2.5	-1.4	-1.1	-0.5	-0.9	-1.3	-1.5	-1.2	-1.6	-0.3	-0.8	-0.0	0.4	-0.0	-0.2	0.2	0.0	-0.1	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	3.3	1.5	0.2	-0.2	0.7	0.4	-0.4	1.8	0.3	0.5	0.4	-1.4	0.2	0.1	0.1	-0.4	-0.2	-0.3	0.2
Medication for cholesterol	0.5	0.7	2.4	0.3	0.3	-0.2	0.8	1.2	-0.3	1.0	0.5	-1.2	-0.2	0.1	-1.3	1.6	0.4	1.3	-0.1	0.8	0.9
Osteoarthritis (self-reported)	0.5	0.7	3.5	-0.0	0.2	-0.2	0.2	-1.6	-0.6	-0.4	0.2	1.9	0.7	-1.0	1.4	-0.8	0.1	-0.6	-1.0	-0.8	-0.1
Eye problems/disorders: Glaucoma	0.5	0.6	1.6	1.1	0.5	0.7	1.1	0.4	0.8	0.7	0.6	1.2	0.2	0.9	0.3	0.4	0.3	0.6	0.8	1.1	1.3
Medication: Atorvastatin	0.5	0.6	2.6	0.5	1.4	0.6	1.3	1.6	0.3	0.4	1.2	0.9	0.7	-0.3	0.4	-0.3	0.3	0.0	-0.5	0.4	0.7
Average weekly beer plus cider intake	0.5	0.7	1.8	0.4	1.1	1.4	0.9	1.3	0.2	0.4	1.1	0.4	0.5	0.8	0.8	0.5	0.9	0.7	1.0	0.5	1.0
Commuting to job workplace: Cycle	0.5	0.6	2.5	0.9	-0.0	-0.2	0.5	-0.7	-1.1	0.3	0.3	-0.9	0.9	0.7	0.3	1.1	1.6	1.2	0.4	0.6	0.8
Rheumatoid Arthritis	0.4	0.5	2.5	0.6	0.3	0.1	0.5	0.0	1.2	0.5	0.8	-1.0	0.3	0.5	-1.6	0.8	0.1	0.3	0.4	1.2	0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.8	7.9	0.4	0.6	0.4	0.5	0.7	2.8	0.1	0.7	1.2	0.8	-0.1	-0.4	-0.1	-0.4	-1.4	-0.3	-0.6	0.4
Lung FVC	0.4	2.1	9.6	-1.4	-1.1	-1.8	-1.1	-1.6	-1.4	-0.6	-1.8	-3.1	-1.1	-0.8	-1.8	0.5	-1.3	0.1	-1.6	-0.8	-1.4
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.2	1.1	0.7	0.9	0.9	-0.5	0.8	1.5	0.5	0.1	0.8	0.4	0.1	0.9	0.5	0.4	0.9	0.7	0.5
Supplements: Zinc	0.4	0.4	2.6	-0.4	-0.4	-0.5	-0.5	0.2	1.5	-0.3	-0.1	-0.4	0.0	0.3	-1.6	0.5	-0.8	-0.7	-0.3	-0.5	-0.5
Qualifications: CSEs or equivalent	0.4	0.5	2.3	0.7	0.4	0.2	0.2	1.5	0.6	0.5	0.4	-0.5	1.3	0.2	-0.1	1.2	0.8	0.1	0.4	-0.5	0.3
Alcohol usually taken with meals	0.4	0.6	2.1	-0.6	-1.4	-0.4	-0.5	-0.7	-1.2	-1.1	-1.2	-0.8	-0.8	0.5	1.0	-0.5	0.4	0.2	0.5	-0.3	-0.5
Worrier / anxious feelings	0.4	0.8	3.0	-0.4	0.4	0.9	0.2	0.4	-0.5	-0.3	0.4	0.9	0.1	1.6	1.0	0.9	1.3	1.7	1.1	1.0	0.8
Falls in the last year	0.4	0.5	2.5	0.1	0.1	-0.2	0.2	-0.4	1.6	-0.3	-0.0	0.7	-0.1	-0.6	-1.4	0.4	-1.3	-1.2	-0.5	-0.4	-0.3
Number of live births	0.4	0.5	2.0	-0.8	0.5	-0.1	0.2	-0.5	0.8	-0.8	0.6	1.4	0.3	-1.1	-0.2	-0.4	-0.4	-0.9	-1.4	-0.6	-0.3
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	3.7	-1.1	-1.3	-1.0	-0.8	0.0	-1.2	-0.3	-1.2	-1.9	-1.4	1.4	-1.4	1.3	0.5	1.6	-0.2	0.3	-0.1
Mouth/teeth dental problems: Dentures	0.4	0.8	2.7	-0.4	-0.6	-0.2	-0.8	-1.2	-1.5	-0.3	-0.8	1.6	-0.7	-0.4	1.4	-1.3	0.0	0.0	-0.3	-0.7	-0.6
Depression (self-reported)	0.4	0.5	1.4	0.3	0.9	1.2	0.7	0.5	0.3	-0.1	0.8	0.3	0.2	0.8	0.8	-0.1	0.7	0.8	0.7	1.0	0.7
Length of working week for main job	0.4	0.4	2.0	-0.6	-0.1	-0.3	0.1	-0.9	-0.8	-0.9	-0.1	-0.5	-0.6	-0.3	1.0	-1.4	-0.0	0.2	-1.0	-0.6	0.1
Exposure to tobacco smoke at home	0.4	0.5	3.1	0.8	0.2	-0.6	0.2	-0.2	1.2	0.7	-0.1	0.9	0.5	-0.5	-1.8	0.7	-0.7	-0.4	-0.4	0.1	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.3	-0.5	0.5	0.7	-0.1	0.9	1.4	-0.6	-0.1	-1.5	-0.2	-0.1	-0.3	-0.5	-1.0	-0.7	0.4	0.4	-0.1
Wheeze or whistling in the chest in last year	0.4	0.6	2.2	0.9	1.3	1.5	0.8	0.6	0.8	0.8	0.6	-0.6	0.7	0.6	0.7	-0.6	0.1	0.6	1.1	0.2	0.8
Health satisfaction	0.4	0.5	1.6	-0.4	-0.3	-0.6	-0.0	-1.1	-0.2	-0.8	-0.2	1.1	-0.0	-1.2	-0.6	0.3	-1.0	-0.9	-0.6	-0.9	-0.8
Medication: Ibuprofen	0.4	0.5	2.3	-0.4	-0.5	-0.2	-1.0	0.2	0.1	-0.4	-0.2	0.6	-0.2	1.5	-1.5	0.9	0.6	1.0	0.7	0.0	-0.3
Knee pain experienced in last month	0.4	0.6	1.8	-0.5	-0.9	-0.8	-0.3	-1.2	-0.2	-1.0	-0.6	1.3	-0.5	-0.9	0.3	-0.6	-0.7	-0.9	-0.9	-0.7	-1.0
Diabetes diagnosed by doctor	0.4	0.6	7.0	-0.2	0.4	0.5	0.1	0.3	2.6	-0.1	0.4	0.2	0.1	0.8	-0.9	-0.2	-0.6	-0.7	-0.3	0.4	0.4
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.5	-0.2	-0.3	0.3	-0.6	0.0	0.6	0.6	-0.6	-1.1	-1.2	1.2	-0.6	-1.0	-0.3	0.2	0.6	0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.3	-0.1	-0.4	-0.4	-0.2	-1.0	-0.1	-0.4	-0.2	1.5	0.6	-1.3	0.8	0.1	-0.2	-1.0	-0.4	-0.9	-0.7
Pain experienced in last month	0.4	0.7	2.6	-0.7	-0.8	-1.0	-0.5	0.4	-1.4	-0.5	-0.7	-1.6	-0.6	-0.9	-0.1	-0.4	-0.2	-0.5	-1.0	-0.8	-0.7
Heart disease (siblings)	0.4	0.5	1.6	-1.3	1.1	1.1	-0.5	0.9	-0.0	0.2	-0.1	-1.1	-0.1	-0.1	-0.6	0.8	-0.5	0.5	0.3	0.2	-0.4
Depressed Affect (Nagel 2018)	0.3	0.7	2.5	0.2	0.7	0.9	0.8	-0.2	0.6	-0.2	1.1	1.6	0.4	0.4	0.5	0.9	0.5	0.7	0.9	1.6	0.7
LDL Cholesterol	0.3	0.4	1.5	-0.9	-0.5	-0.4	-0.8	-1.1	-0.3	-0.4	-0.8	-1.2	-0.4	-0.5	0.1	-0.0	-0.5	-0.3	-0.5	-0.5	-0.9
Lupus	0.3	0.4	2.2	-0.5	0.7	0.4	0.4	0.9	-0.2	-1.0	0.5	1.5	0.2	-0.8	0.2	0.6	-0.1	0.0	-0.1	0.7	-0.2
Primary Biliary Cirrhosis	0.3	0.4	1.5	0.3	0.6	-0.1	0.7	1.2	0.7	-0.1	0.5	0.1	0.6	-1.1	-0.1	-0.5	-0.5	-1.0	-1.0	-0.4	0.3
Height	0.3	5.2	19.4	0.5	1.4	1.8	1.0	2.5	1.1	1.6	1.3	-0.8	-0.1	4.4	-1.7	1.8	2.1	3.6	2.6	4.0	3.1
Chronotype (morning person)	0.3	0.7	2.0	0.0	1.0	1.1	0.7	-0.0	1.2	0.5	0.9	0.2	0.9	1.4	-0.3	0.6	1.0	0.7	0.6	1.1	1.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.4	-0.5	0.2	0.7	-0.1	-0.5	1.0	-0.5	-0.0	-0.6	0.0	-0.5	1.1	-1.0	-0.8	-1.2	0.3	0.3	-0.3
Trunk fat percentage	0.3	1.2	6.2	-1.2	-0.3	-0.8	-0.5	-1.6	-0.1	-1.5	-0.7	0.6	-1.2	-0.7	0.3	-2.5	-1.0	-0.8	-1.8	-0.3	-0.1
Current tobacco smoking	0.3	0.5	2.4	-0.5	-0.0	-0.1	-0.5	-1.4	-0.4	-0.1	-0.8	0.4	-0.5	-0.7	0.1	-1.5	-0.6	-0.8	-0.5	-0.6	-0.7
Maternal smoking around birth	0.3	0.4	1.1	0.1	0.9	1.0	0.3	-0.5	0.4	0.6	0.4	0.8	0.4	0.5	0.2	0.9	0.1	0.7	0.7	0.8	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	0.8	1.0	0.4	0.9	0.8	0.3	0.6	1.1	0.4	0.4	-1.1	0.1	-0.4	-0.2	-0.6	-0.0	0.5	0.2
High blood pressure	0.3	0.7	2.4	-0.7	-0.5	-0.3	-0.4	-1.1	-1.4	-1.5	-0.8	0.5	-0.3	-1.0	1.5	-1.0	-0.0	-0.6	-0.4	-0.5	-0.7
Had menopause	0.3	0.3	1.3	-0.1	-0.3	0.1	-0.4	-0.0	-0.8	0.5	-0.3	-0.5	-0.9	0.9	0.2	-0.5	0.1	1.0	0.8	1.2	-0.1
Had other major operations	0.3	0.3	0.9	0.6	0.2	0.6	0.4	-0.8	0.7	0.6	0.6	0.8	0.7	-0.5	0.1	0.6	-0.1	-0.5	0.9	0.2	-0.1
Forced vital capacity (FVC)	0.3	1.0	7.3	-0.9	-0.8	-0.8	-0.4	0.1	-1.1	-0.0	-1.1	-2.7	-1.2	0.9	-1.2	0.7	0.3	1.2	-0.4	0.2	0.0
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	2.1	-0.9	0.0	0.0	-0.5	0.2	0.5	-0.5	-0.2	-1.4	0.1	0.1	-0.8	1.0	-0.4	0.5	0.1	0.2	-0.2
Financial difficulties in last 2 years	0.3	0.4	1.8	-0.3	-0.7	-0.6	-0.8	-1.3	-0.2	-0.3	-0.9	-1.2	-0.8	0.0	-0.5	-0.5	-0.2	-0.2	0.2	-0.3	-0.5
Diabetes (self-reported)	0.3	0.5	2.9	-0.6	-0.1	-0.2	-0.3	0.3	1.7	-0.5	0.1	0.0	-0.1	-0.4	-0.7	-0.5	-0.8	-1.2	-1.1	-0.5	-0.3
Neuroticism score	0.3	0.7	2.7	-0.4	0.6	1.2	0.2	0.3	0.5	-0.4	0.6	0.5	0.0	1.3	0.3	1.0	0.5	1.3	1.4	1.7	0.5
Alcohol intake versus 10 years previously	0.3	0.4	1.8	0.8	0.7	0.2	0.1	-0.7	1.4	1.1	0.4	1.3	0.3	0.0	-0.8	0.4	-0.5	-0.2	0.0	-0.3	0.1
Medication: Cholesterol lowering	0.3	0.4	1.7	0.6	0.1	0.3	0.4	0.3	1.2	0.5	0.2	1.3	0.1	1.0	-0.5	-0.1	0.1	-0.1	0.4	0.6	1.1
Standing height	0.3	2.6	6.9	0.9	1.5	1.6	1.5	2.1	0.7	1.4	1.2	-0.2	0.1	2.2	-0.5	1.2	1.8	2.3	1.7	2.3	2.6
Birth weight of first child	0.3	0.6	2.9	1.1	-0.1	-0.1	0.1	0.1	1.7	0.6	-0.1	0.1	0.7	1.0	-1.4	1.4	0.2	-0.1	0.5	0.2	0.3
Headache pain in last month	0.3	0.5	3.2	0.2	0.1	0.6	0.0	0.6	1.3	-0.9	0.3	-0.2	-0.2	1.8	0.2	-0.7	0.5	0.3	0.5	0.4	0.7
Exposure to tobacco smoke outside home	0.3	0.4	2.0	1.2	0.6	0.6	-0.0	0.4	0.7	1.4	0.1	-0.4	0.8	0.2	0.2	0.1	0.2	-0.2	0.8	-0.3	0.1
Worry too long after embarrassment	0.3	0.5	2.2	-1.3	-0.2	0.6	-0.2	0.6	0.3	-1.5	-0.2	1.0	-0.8	0.1	1.0	-0.7	-0.2	-0.3	0.3	-0.7	-0.3
Medication: Omeprazole	0.3	0.3	1.8	-0.6	0.3	0.2	-0.3	-1.4	-0.1	0.1	-0.6	0.5	-0.4	-0.6	-0.1	-0.8	-0.7	-0.7	-0.1	-0.5	-0.3
Pulse rate, automated reading	0.3	1.0	5.2	0.3	-0.7	-0.3	-0.2	-1.3	-0.2	0.3	-0.3	0.7	-1.3	1.6	-1.6	0.3	0.0	1.2	1.4	2.3	0.1
Hypertension (Self-reported)	0.3	0.8	3.2	-0.7	-0.4	-0.3	-0.4	-1.3	-1.4	-1.7	-0.6	0.5	-0.2	-0.9	1.8	-1.3	0.2	-0.6	-0.6	-0.5	-0.5
Illnesses of father: Heart disease	0.3	0.4	1.7	0.8	0.4	0.3	0.0	0.3	-0.0	1.3	0.4	-0.1	0.4	1.1	-0.4	0.5	0.3	1.2	0.6	0.9	0.4
Medication: Gliclazide	0.3	0.3	2.2	-0.9	-0.4	0.7	-0.4	-0.3	0.5	-0.5	-0.3	-0.3	-0.7	1.5	0.6	-0.3	0.2	0.3	0.6	0.3	0.1
Illnesses of father: None of the above (group 1)	0.3	0.3	1.7	0.0	-0.4	-0.1	0.0	0.3	-1.3	-0.3	-0.0	0.1	-0.1	0.4	0.4	1.0	1.3	0.8	0.7	0.3	0.0
Financial situation satisfaction	0.3	0.4	1.6	-0.4	0.0	-0.2	-0.1	-1.2	-0.5	-0.4	-0.3	-0.8	-0.1	-1.2	0.5	-0.8	-0.7	-0.9	-0.4	-0.7	-0.7
Unable to work because of sickness or disability	0.3	0.4	1.6	-0.6	0.4	0.3	-0.4	-0.1	1.1	-0.2	0.1	1.3	-0.3	0.3	-1.2	0.2	-0.9	0.1	0.2	0.3	-0.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.5	-0.5	-0.9	-0.4	-0.8	1.1	-0.8	-0.2	-0.6	-1.1	-1.2	1.5	-0.8	0.4	0.5	1.6	-0.0	0.8	-0.2
Alzheimer’s Disease (including proxy)	0.2	0.4	1.6	0.5	0.4	0.3	0.7	-0.5	0.8	0.6	0.5	0.2	0.8	-1.2	0.4	-0.4	-0.4	-0.8	0.1	-0.6	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.9	0.5	-0.4	0.4	-0.1	0.6	0.0	1.0	0.2	0.3	-0.2	1.4	0.6	-0.1	0.5	1.1	1.2	0.9	0.6
Bipolar Disorder (2011)	0.2	0.2	1.0	0.2	0.1	0.2	0.3	0.4	0.4	0.3	0.2	0.0	-0.1	0.6	-1.0	0.4	0.1	0.4	0.2	0.5	0.4
Crohns Disease (2012)	0.2	0.3	1.1	0.5	0.7	1.0	0.6	0.1	0.5	0.6	0.4	-0.7	0.2	-0.0	-0.1	0.8	0.1	0.3	1.0	0.3	0.4
Blood Red Count	0.2	1.7	4.2	-1.3	-1.2	-1.6	-1.2	-1.5	-0.5	-1.3	-1.4	0.1	-1.0	-2.1	-0.8	-0.9	-1.8	-1.3	-1.3	-1.2	-1.8
Systolic Blood Pressure	0.2	0.8	2.9	-0.6	-1.3	-0.7	-0.9	0.2	-1.5	-1.5	-0.9	1.7	-0.4	0.9	1.2	-0.1	0.6	0.7	0.2	0.2	-0.4
Respiratory disease	0.2	0.4	1.7	0.2	-0.6	-0.6	-0.2	-0.7	-1.3	0.2	-0.7	-1.2	-0.5	0.2	0.5	-0.8	0.5	0.4	-0.3	-0.7	-0.2
Taking other prescription medications	0.2	0.3	1.2	-0.6	0.3	0.3	-0.3	-0.5	0.9	-0.0	-0.3	-0.3	-0.4	0.1	-0.3	-0.9	-1.1	-0.6	-0.2	-0.2	-0.2
Medication: Levothyroxine sodium	0.2	0.3	1.2	-0.6	-0.0	-0.3	-0.5	-0.2	-0.8	-0.8	-0.3	0.4	-0.6	0.4	0.2	-1.0	0.3	0.3	-1.1	-0.4	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	-0.2	0.6	1.0	-0.2	-0.2	0.7	-0.2	0.3	-0.7	0.3	0.4	1.0	-0.8	-0.2	-0.2	0.7	0.4	0.0
Hearing difficulty/problems with background noise	0.2	0.4	1.9	-0.7	0.9	0.8	0.1	0.2	1.4	-0.6	0.2	-0.4	-0.5	-0.3	-0.5	-0.6	-1.1	-0.3	0.2	-0.1	-0.1
Qualifications: None of the above	0.2	0.4	1.5	-0.1	1.0	0.6	-0.2	-0.5	1.1	0.6	0.1	0.6	0.4	-0.6	-1.1	0.3	-1.2	-0.5	0.2	0.6	-0.5
Illnesses of siblings	0.2	0.3	1.7	1.3	-0.7	-0.5	0.1	-0.4	-0.1	1.2	-0.1	-0.5	0.1	0.4	-0.3	0.5	0.5	0.3	0.5	0.0	0.3
Noisy workplace	0.2	0.2	0.9	-0.2	0.5	0.5	0.2	0.5	0.4	0.5	-0.1	-1.0	-0.4	-0.5	-0.6	-0.0	-1.0	-0.2	0.2	0.3	-0.3
Asthma	0.2	0.4	2.6	-0.0	-0.7	-0.1	-0.6	0.5	-0.2	0.2	-1.0	-1.6	-0.8	1.0	0.1	-0.7	-0.0	0.5	0.5	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.0	-0.8	-0.5	-0.2	-0.1	0.5	-0.6	0.0	-0.5	-0.7	-0.8	1.4	-1.0	1.6	0.6	1.7	0.4	0.5	0.4
Pulse wave reflection index	0.2	0.2	0.6	0.3	0.4	0.6	0.4	0.6	-0.1	0.1	0.6	-0.4	0.5	0.6	0.8	0.4	0.7	0.7	0.2	0.3	0.5
Loud music exposure frequency	0.2	0.2	0.7	-0.0	-0.0	0.2	-0.1	-0.8	-0.0	0.3	0.1	-0.3	-0.3	-0.7	0.7	-0.8	-0.8	-0.6	0.2	-0.1	-0.7
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.8	0.2	0.3	0.4	-0.2	0.5	0.2	0.0	-0.1	-1.3	0.4	0.8	0.6	-0.5	0.6	0.3	0.2	0.0	0.7
Forced vital capacity (FVC), Best measure	0.2	0.7	2.6	-0.3	0.1	0.3	0.4	0.9	-0.5	0.6	-0.2	-1.3	-0.4	1.1	-0.7	1.6	0.6	1.6	0.6	0.6	0.6
Shortness of breath walking on level ground	0.2	0.2	1.0	0.1	0.7	0.6	0.3	0.8	1.0	0.3	0.4	-0.1	-0.4	-0.1	-0.3	-0.3	-0.7	0.1	0.4	0.3	0.5
Qualifications: College or University degree	0.2	0.6	2.4	-0.4	-0.5	-0.6	0.3	0.1	0.6	-1.4	0.1	1.2	0.2	-1.1	0.0	-0.6	-0.1	-1.5	-0.9	-1.5	-0.3
Migraine (self-reported)	0.2	0.3	1.1	-0.0	-0.9	-0.4	0.0	-0.7	0.2	-0.9	-0.4	0.9	-0.6	1.1	0.2	-0.1	-0.1	0.5	0.3	0.4	0.1
Medication: Seretide 50 evohaler	0.2	0.3	1.6	0.3	0.2	0.1	-0.2	0.7	-0.5	0.9	-0.0	-0.5	-0.5	0.7	0.0	-0.4	0.3	1.2	0.3	0.0	0.4
Mean time to correctly identify matches	0.2	0.5	1.7	-0.7	0.1	0.1	0.0	0.2	-0.9	-0.7	0.1	-1.3	-0.8	1.0	0.5	-0.9	0.8	1.1	-0.2	0.2	0.7
Comparative height size at age 10	0.2	0.9	3.6	-0.9	0.1	-0.8	0.2	-0.7	0.4	-0.7	-0.3	-0.5	-1.0	-1.9	-1.1	-0.8	-1.1	-1.2	-1.9	-0.9	-0.2
Overall health rating	0.2	0.4	2.5	0.0	1.6	0.9	0.7	0.2	-0.2	0.5	0.8	0.9	0.6	-0.9	0.8	-0.2	-0.4	0.3	-0.3	0.0	0.1
Age at last live birth	0.2	0.4	1.6	-0.0	0.6	0.4	0.5	1.2	1.3	-0.1	0.6	0.5	-0.1	-0.6	-0.4	-0.2	-0.8	-0.9	-0.2	0.0	0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.0	-1.0	-0.3	-0.3	-0.1	0.5	-0.3	-0.9	-0.1	0.3	-0.1	-0.5	0.1	-0.3	-0.2	-0.4	-0.4	-1.0	-0.3
Back pain experienced in last month	0.2	0.2	1.1	0.5	0.1	0.6	-0.3	-1.1	0.5	0.5	-0.1	0.6	-0.2	0.2	0.1	0.3	-0.1	0.2	1.0	0.1	-0.3
Asthma (self-reported)	0.2	0.3	1.9	0.3	-0.6	0.1	-0.4	0.5	-0.0	0.3	-0.8	-1.4	-0.6	1.0	0.4	-0.7	0.2	0.4	0.7	-0.2	-0.0
Smoking status: Current	0.2	0.3	1.4	-0.1	0.0	-0.1	-0.5	-1.2	-0.5	0.4	-0.8	0.2	-0.4	-0.7	-0.1	-1.0	-0.5	-0.5	-0.3	-0.6	-0.7
Average weekly champagne plus white wine intake	0.2	0.3	1.0	0.9	-0.9	-0.4	0.6	-0.3	-0.7	0.3	-0.2	0.4	0.1	-0.0	0.9	0.6	1.0	0.0	0.4	0.8	0.4
Miserableness	0.2	0.3	1.6	-1.3	-0.2	-0.3	-0.7	-0.1	-0.2	-0.8	-0.4	-0.4	-0.8	0.4	-0.5	0.1	-0.6	0.4	-0.6	0.5	-0.8
Guilty feelings	0.2	0.3	1.5	-0.5	0.1	0.5	0.0	0.6	1.2	-0.7	0.0	0.8	-0.5	0.5	0.1	-0.5	-0.9	-0.1	0.4	0.7	0.2
Myopia	0.2	0.3	1.7	0.2	0.3	-0.0	-0.5	1.1	0.6	0.4	-0.0	0.4	-0.0	0.7	-1.3	0.2	-0.4	0.3	0.1	0.3	-0.0
Vascular/heart problems diagnosed by doctor	0.2	0.6	5.5	0.1	-0.5	-0.9	-0.3	0.3	1.0	0.8	-0.1	-0.7	-0.5	0.2	-2.3	0.6	-0.7	-0.1	-0.4	-0.1	-0.2
Cholesterol lowering medication	0.2	0.2	1.1	0.6	0.4	0.6	0.2	0.2	-0.1	0.7	0.1	0.0	1.0	-0.5	0.7	0.3	-0.2	-0.1	0.8	0.0	-0.3
Alzheimer’s Disease (in mother)	0.1	0.1	0.6	-0.4	-0.4	-0.4	-0.4	-0.6	-0.6	-0.2	-0.1	0.2	0.0	-0.0	-0.3	-0.8	-0.0	0.1	0.2	0.4	-0.1
Crohns Disease (2017)	0.1	0.3	0.8	0.9	0.8	0.6	0.6	0.3	0.1	0.7	0.5	0.6	0.8	-0.7	0.1	0.4	0.2	-0.1	0.4	-0.4	0.2
Prostate Cancer	0.1	0.1	1.3	-0.2	-0.1	-0.0	0.0	-0.2	-1.1	0.5	-0.2	0.0	-0.4	0.1	0.3	-0.1	0.1	0.7	0.4	0.2	0.1
Blood Eosinophil Count	0.1	0.8	3.1	-0.1	1.0	0.8	0.9	0.1	0.7	-0.5	0.6	0.2	0.9	-1.6	1.4	-0.3	-0.0	-1.1	-0.8	-1.8	-0.1
Blood White Count	0.1	1.1	3.6	-0.7	0.8	1.9	-0.2	-0.3	0.2	-0.6	0.2	0.6	-0.2	1.9	1.3	-0.2	0.9	1.2	1.8	1.4	0.9
Waist Hip Ratio (WHR)	0.1	0.5	3.1	0.5	0.1	-0.4	0.1	0.7	0.3	0.0	0.4	1.4	-0.1	-0.2	-1.4	0.9	-0.5	0.3	-0.1	1.8	0.0
Cardiovascular Disease	0.1	0.4	2.6	0.6	-0.6	-0.3	0.0	-0.6	-1.1	-0.5	-0.1	1.6	0.5	-0.6	1.0	0.3	0.5	-0.2	0.2	-0.1	-0.3
Tanning	0.1	1.1	3.6	-0.8	-1.2	-0.7	-0.2	-1.0	-1.2	-1.7	-0.7	1.5	-1.1	0.6	1.4	-1.9	-0.1	-0.3	-0.6	-0.8	-0.2
Systolic blood pressure, automated reading	0.1	0.4	4.1	-0.2	-0.4	-0.3	-0.2	0.0	-0.6	-1.0	-0.2	2.0	-0.4	0.1	0.4	-0.2	-0.1	0.1	-0.1	0.3	-0.3
Fed-up feelings	0.1	0.2	1.0	-0.5	0.3	0.2	-0.1	-0.6	0.3	-0.3	0.1	-0.1	-1.0	0.2	-0.5	0.0	-0.6	0.6	-0.0	0.9	-0.1
Sitting height	0.1	0.4	1.1	-0.6	-0.2	0.0	-0.0	1.0	-0.6	-0.3	-0.3	-0.8	-1.0	1.0	0.3	-0.5	0.7	0.9	-0.1	0.3	0.8
Medication: Simvastatin	0.1	0.2	0.6	0.1	-0.5	-0.0	-0.6	-0.2	0.3	0.2	-0.6	-0.2	0.4	0.2	0.0	0.8	-0.4	-0.3	0.6	0.2	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.3	0.2	0.6	-0.1	-0.0	0.3	0.3	0.0	-0.5	0.1	0.3	0.7	-0.2	0.1	-0.1	0.6	0.5	0.1
Prospective memory result	0.1	0.2	0.4	0.6	0.2	-0.2	0.6	0.7	0.2	0.3	0.6	0.4	0.5	0.1	-0.4	0.5	0.3	0.1	-0.4	0.2	0.5
Hair/balding pattern: Pattern 4	0.1	0.3	2.2	0.0	0.1	0.3	-0.2	0.4	0.0	0.5	0.1	0.3	-0.2	1.5	-0.0	-0.1	0.2	0.7	0.6	0.8	0.4
Age at first live birth	0.1	0.2	1.6	-0.3	-0.4	-0.3	-0.1	1.3	0.0	-0.8	-0.1	0.5	-0.0	-0.5	-0.1	0.5	-0.5	-0.5	-0.1	-0.2	-0.4
Long-standing illness, disability or infirmity	0.1	0.1	0.6	-0.3	-0.2	0.0	-0.3	-0.6	0.8	-0.1	-0.2	0.6	-0.3	0.1	-0.6	-0.1	-0.4	-0.3	0.0	-0.4	-0.1
Ever had bowel cancer screening	0.1	0.1	0.7	-0.2	0.0	-0.1	0.1	0.0	-0.0	-0.1	0.1	-0.4	-0.5	-0.6	0.0	-0.8	-0.7	-0.1	-0.5	-0.0	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	1.1	-0.3	0.5	0.4	-0.1	-1.1	-0.3	0.7	-0.4	0.2	-0.1	-0.3	-0.5	0.1	-0.3	-0.2	0.3	-0.0	-0.1
Hair Pigment	0.0	0.9	3.0	1.1	0.4	0.8	0.3	-0.1	0.4	1.2	0.7	-1.2	1.4	0.6	0.3	1.6	0.8	0.8	1.7	0.9	0.5

Hub : Genes

C16orf62

Models

Trait associations