[Hub]/) : Traits : Impedance of arm (right) : ← →

chr22:37,781,874-39,355,109

Best TWAS P=8.96e-18 · Best GWAS P=1.48e-17 conditioned to 0.0194

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous BAIAP2L2 0.11 0.03 lasso 5 0.04 1.8e-04 5.7 -7.7 1.3e-14 -0.75 0.09 0.60 FALSE
2 GTEx Artery Aorta TMEM184B 0.17 0.07 enet 34 0.03 1.2e-02 7.2 -7.0 2.1e-12 -0.67 0.05 0.75 FALSE
3 GTEx Artery Aorta AL021977.1 0.13 0.00 enet 17 0.01 8.7e-02 8.2 -7.1 1.2e-12 -0.73 0.02 0.82 FALSE
4 GTEx Brain Cortex TMEM184B 0.29 0.12 lasso 7 0.09 1.6e-03 7.2 -6.9 5.3e-12 -0.90 0.01 0.89 FALSE
5 GTEx Cells EBV-transformed lymphocytes PLA2G6 0.28 0.17 enet 13 0.18 1.3e-06 -5.4 6.6 5.0e-11 0.70 0.13 0.79 FALSE
6 GTEx Cells Transformed fibroblasts PLA2G6 0.23 0.09 lasso 9 0.10 9.9e-08 6.2 6.8 1.0e-11 0.83 0.19 0.81 FALSE
7 GTEx Esophagus Gastroesophageal Junction PLA2G6 0.28 0.24 lasso 5 0.23 1.1e-08 -5.4 5.9 3.4e-09 0.65 0.43 0.50 FALSE
8 GTEx Esophagus Mucosa PLA2G6 0.22 0.02 lasso 6 0.04 1.9e-03 6.2 6.5 9.0e-11 0.80 0.04 0.95 FALSE
9 GTEx Nerve Tibial PLA2G6 0.34 0.08 lasso 8 0.11 2.9e-08 -5.4 6.5 5.6e-11 0.74 0.12 0.88 FALSE
10 GTEx Nerve Tibial MAFF 0.14 0.06 lasso 3 0.05 1.2e-04 8.5 -8.2 1.9e-16 -0.99 0.00 1.00 FALSE
11 GTEx Skin Sun Exposed Lower leg BAIAP2L2 0.09 0.09 lasso 4 0.09 5.5e-08 5.5 -5.6 1.6e-08 -0.77 0.21 0.79 FALSE
12 GTEx Thyroid PLA2G6 0.34 0.20 lasso 5 0.18 4.5e-14 -5.4 6.2 6.9e-10 0.68 0.88 0.12 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PLA2G6 0.05 0.01 blup 76 0.01 7.7e-02 7.5 8.6 9.0e-18 0.85 0.01 0.79 TRUE
14 The Cancer Genome Atlas Thyroid Carcinoma PLA2G6 0.03 0.02 lasso 2 0.03 6.5e-04 7.0 6.9 6.5e-12 0.82 0.07 0.32 FALSE