[Hub]/) : Traits : Impedance of arm (left) :

chr11:16,343,081-18,106,069

Best TWAS P=7.25e-11 · Best GWAS P=1.87e-09 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KCNJ11 0.04 0.03 lasso 3 0.03 2.6e-04 5.6 5.9 3.9e-09 0.93 0.02 0.97 TRUE
2 GTEx Cells Transformed fibroblasts PIK3C2A 0.10 0.08 lasso 4 0.08 1.3e-06 5.6 -5.4 5.5e-08 -0.60 0.14 0.84 FALSE
3 GTEx Esophagus Mucosa KCNJ11 0.27 0.16 lasso 8 0.22 1.6e-14 -4.5 -5.8 5.3e-09 -0.77 0.35 0.65 FALSE
4 GTEx Esophagus Mucosa NCR3LG1 0.38 0.38 enet 39 0.42 3.7e-30 -4.5 -5.6 1.9e-08 -0.72 0.89 0.11 FALSE
5 GTEx Esophagus Mucosa RP1-239B22.5 0.28 0.28 enet 47 0.32 2.9e-22 -4.6 -5.8 7.2e-09 -0.74 0.88 0.12 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic KCNJ11 0.18 0.07 lasso 6 0.12 7.0e-07 5.6 -6.0 1.6e-09 -0.85 0.01 0.99 FALSE
7 GTEx Skin Sun Exposed Lower leg OR7E14P 0.11 0.05 lasso 6 0.08 4.3e-07 4.8 -5.6 2.0e-08 -0.48 0.31 0.66 FALSE
8 GTEx Skin Sun Exposed Lower leg KCNJ11 0.23 0.09 lasso 10 0.12 1.7e-10 5.9 -6.1 8.1e-10 -0.89 0.01 0.99 FALSE
9 GTEx Skin Sun Exposed Lower leg NCR3LG1 0.12 0.12 lasso 5 0.13 5.0e-11 -4.9 -5.2 1.8e-07 -0.53 0.77 0.22 FALSE
10 GTEx Skin Sun Exposed Lower leg RP1-239B22.5 0.06 0.06 lasso 2 0.07 8.6e-07 -4.9 -6.0 2.1e-09 -0.83 0.02 0.97 FALSE
11 GTEx Small Intestine Terminal Ileum OR7E14P 0.29 0.10 enet 19 0.22 1.3e-05 -3.2 -5.3 1.0e-07 -0.49 0.18 0.28 TRUE
12 GTEx Thyroid RP1-239B22.5 0.08 0.07 enet 16 0.08 1.8e-06 6.0 -5.2 2.1e-07 -0.84 0.00 0.99 TRUE
13 ROSMAP Brain Pre-frontal Cortex KCNJ11 0.05 0.06 enet 6 0.05 3.0e-07 4.8 5.1 2.9e-07 0.73 0.19 0.79 TRUE
14 The Cancer Genome Atlas Breast Invasive Carcinoma ABCC8 0.05 0.05 lasso 3 0.04 1.7e-09 5.6 -5.6 1.7e-08 -0.09 0.03 0.97 TRUE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DKFZp686O24166 0.05 0.03 blup 71 0.04 1.2e-05 -4.9 -6.5 7.2e-11 -0.81 0.02 0.98 TRUE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DKFZp686O24166 0.03 0.01 blup 72 0.03 2.4e-04 5.9 -5.9 2.9e-09 -0.83 0.01 0.95 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DKFZp686O24166 0.08 0.07 lasso 4 0.05 1.2e-03 -4.6 -5.6 2.7e-08 -0.72 0.04 0.92 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma ABCC8 0.10 0.06 enet 10 0.05 8.5e-06 5.6 -5.1 2.7e-07 -0.08 0.03 0.96 TRUE