Best TWAS P=5.54e-10 · Best GWAS P=7.18e-10 conditioned to 0.0521
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | COPA | 0.09 | 0.08 | lasso | 2 | 0.08 | 6.1e-10 | 6.1 | -6.2 | 7.8e-10 | -0.83 | 0.00 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | COPA | 0.05 | 0.03 | lasso | 3 | 0.03 | 8.3e-04 | 6.2 | -6.2 | 7.8e-10 | -1.00 | 0.00 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NCSTN | 0.06 | 0.02 | blup | 46 | 0.03 | 9.8e-04 | 4.9 | -6.2 | 5.5e-10 | -0.81 | 0.01 | 0.90 | TRUE |