TWAS hub - NCSTN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Whole Blood	0.1880	0.0400	2.7e-12	0.165	NA	0.184	NA	0.182	4.6e-15	NA	1.1e-16	NA	1.6e-16
2	NTR	Blood	0.0386	0.0092	2.9e-11	0.044	0.028	0.046	0.039	0.046	3.9e-14	1.5e-09	1.5e-14	1.6e-12	1.3e-14
3	YFS	Blood	0.1439	0.0192	0.0e+00	0.257	0.239	0.265	0.261	0.260	1.7e-83	3.2e-77	1.4e-86	4.5e-85	8.8e-85
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0334	0.0189	5.5e-03	0.001	0.014	0.015	NA	0.007	2.7e-01	8.7e-03	7.9e-03	NA	4.6e-02
5	TCGA	Brain Lower Grade Glioma	0.0281	0.0160	4.0e-03	-0.001	0.017	0.008	NA	0.003	4.3e-01	4.2e-03	3.9e-02	NA	1.3e-01
6	TCGA	Ovarian Serous Cystadenocarcinoma	0.0590	0.0290	1.7e-03	0.012	0.031	0.034	NA	0.018	5.0e-02	3.6e-03	2.1e-03	NA	2.1e-02
7	TCGA	Prostate Adenocarcinoma	0.0624	0.0364	2.6e-03	0.020	0.025	0.008	NA	0.012	3.2e-03	9.8e-04	4.5e-02	NA	1.7e-02
8	TCGA	Uterine Corpus Endometrial Carcinoma	0.2850	0.1200	2.1e-03	0.123	0.089	0.161	NA	0.137	2.6e-04	1.8e-03	3.0e-05	NA	1.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Neuroticism (2016)	4.7	6.8	16.2	-3.5	-4.0	-3.7	1.1	-2.5	-2.1	-0.4	-0.1
Illnesses of father: High blood pressure	4.4	5.5	12.5	3.5	3.3	3.3	-1.2	1.4	1.2	-2.2	-0.6
Schizophrenia (2018)	4.1	8.5	12.9	3.0	3.1	2.5	0.6	3.3	3.5	3.6	2.4
Bipolar Disorder or Schizophrenia	4.0	9.7	14.9	3.1	3.2	2.7	0.1	3.7	3.9	3.2	3.4
Breastfed as a baby	3.7	4.6	11.1	-3.3	-3.1	-2.9	0.3	-1.8	-2.0	0.1	-0.4
Schizophrenia (2014)	3.6	7.9	11.9	2.9	3.0	2.6	0.3	3.5	3.4	2.8	2.7
Waist Hip Ratio (WHR)	3.5	16.0	31.4	5.6	5.2	4.5	0.3	4.5	4.3	2.1	2.4
Suffer from ‘nerves’	3.4	5.3	10.2	-3.1	-3.0	-2.7	-1.9	-1.1	-3.2	-1.0	-0.6
Stomach or abdominal pain in last month	3.3	4.1	7.7	2.3	2.1	2.1	1.2	2.1	2.8	1.2	1.9
Loneliness, isolation	3.3	4.5	8.4	-2.4	-2.9	-2.5	0.1	-2.5	-2.3	-2.0	-0.4
Health satisfaction	3.1	4.1	8.1	2.8	2.3	2.4	-0.5	2.3	1.8	0.6	2.1
Alzheimer’s Disease (in father)	3.0	3.3	10.6	1.2	0.9	0.9	0.1	2.0	2.4	1.7	3.3
Hair/balding pattern: Pattern 3	2.7	4.1	14.7	-1.5	-1.2	-1.7	3.8	-1.5	1.1	2.4	1.4
Medication for cholesterol	2.7	4.1	7.6	-2.4	-2.7	-2.5	-1.0	-1.9	-2.8	-0.8	-0.7
Mean Putamen Volume	2.6	3.0	8.1	1.6	1.9	1.8	1.1	1.1	2.8	0.9	1.8
Allergy or Eczema	2.6	6.8	14.9	-3.9	-3.7	-3.6	1.3	-2.6	-1.8	0.9	-0.6
Worry too long after embarrassment	2.6	4.3	10.0	-3.1	-3.2	-3.2	-0.5	-1.2	-1.8	-0.0	0.5
Wears glasses or contact lenses	2.6	3.0	7.4	-0.9	-1.1	-0.8	-0.1	-2.7	-1.7	-2.4	-2.3
Type 2 Diabetes (T2D) (2012)	2.5	2.9	4.7	-2.2	-2.1	-2.0	1.3	-2.1	-1.2	-1.1	-1.2
Hand grip strength (right)	2.5	6.7	17.7	-2.3	-1.8	-2.8	2.7	-0.4	0.6	4.2	3.4
Hayfever, allergic rhinitis or eczema	2.5	5.4	12.8	-3.6	-3.5	-3.2	0.8	-2.0	-1.6	0.5	-0.5
Chronic bronchitis/emphysema (father)	2.4	2.8	5.7	2.0	2.4	2.2	-1.0	2.2	1.4	0.5	0.3
Fluid intelligence score	2.4	5.0	8.3	-2.7	-2.6	-2.6	1.0	-2.9	-2.5	-0.5	-1.7
Noisy workplace	2.4	2.9	5.5	1.2	1.1	0.8	0.6	2.1	2.2	2.3	2.3
Impedance of arm (right)	2.3	10.8	39.2	0.8	0.4	1.2	-3.8	-1.7	-3.0	-6.3	-4.3
Mouth/teeth dental problems: Mouth ulcers	2.3	3.7	11.9	0.5	0.5	0.4	1.4	1.6	2.5	2.5	3.5
Lupus	2.2	3.4	8.5	2.0	1.9	1.8	-0.1	2.9	1.4	1.6	1.9
Medication: Levothyroxine sodium	2.2	3.8	7.2	1.4	1.9	1.4	0.8	2.7	2.4	2.2	2.0
Hypothyroidism/myxoedema (self-reported)	2.2	4.2	7.7	2.0	2.2	1.9	0.3	2.8	2.5	2.2	1.6
Had major operations	2.2	2.5	5.3	1.6	2.0	1.7	1.6	0.9	2.3	0.8	1.2
Illnesses of father: None of the above (group 1)	2.2	2.7	5.1	-2.1	-2.3	-1.9	0.0	-1.6	-2.0	-1.0	-1.0
Intelligence (Savage-Jansen 2018)	2.1	6.3	14.2	-2.8	-3.1	-3.0	2.4	-3.8	-1.8	0.1	-0.8
Bipolar Disorder (2011)	2.1	2.0	3.8	1.3	1.3	1.0	0.7	1.6	1.9	1.9	1.2
Allergy	2.1	4.9	11.4	3.4	3.3	3.1	-1.1	2.0	0.9	-1.0	-0.6
Impedance of arm (left)	2.1	9.8	38.4	1.3	1.0	1.8	-3.5	-1.1	-2.2	-6.2	-3.9
High cholesterol (Self-reported)	2.1	3.7	8.6	2.5	2.3	2.1	-1.7	2.9	0.9	1.2	0.7
Mouth/teeth dental problems: Dentures	2.0	3.3	7.7	-2.4	-2.6	-2.8	-0.1	-1.4	-1.8	0.6	-1.1
Pulse wave reflection index	2.0	2.5	6.1	1.6	1.8	1.5	-2.5	2.3	0.6	0.5	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.5	4.8	-1.6	-2.2	-1.9	-0.2	-1.6	-1.7	-1.8	-0.1
Hypothyroidism (self reported)	1.8	4.0	7.2	1.9	2.1	1.6	1.0	2.2	2.7	2.3	1.7
Supplements: Vitamin C	1.8	2.1	4.4	-1.7	-2.0	-2.1	1.6	-1.2	-0.3	0.9	0.9
Basal cell carcinoma (self-reported)	1.8	2.2	6.2	2.5	2.2	2.0	-0.5	1.3	0.8	-0.2	0.2
Lung FVC	1.7	8.8	17.2	3.1	2.9	2.6	-0.0	3.5	3.4	2.2	4.1
Hand grip strength (left)	1.7	4.4	8.4	-2.1	-1.7	-2.3	2.5	-0.8	0.2	2.9	2.9
Commuting to job workplace: Walk	1.7	1.9	3.7	1.4	1.7	1.9	-0.9	0.1	-0.0	-1.4	-1.8
Unable to work because of sickness or disability	1.7	2.2	9.7	-0.6	-0.4	-0.7	0.7	1.0	1.0	3.1	2.1
Neuroticism (Nagel 2018)	1.6	3.7	8.0	-2.5	-2.8	-2.5	-0.8	-1.4	-2.2	-1.1	-0.9
Verbal and Numeric Reasoning (VNR)	1.6	3.8	7.2	-2.3	-2.3	-2.1	0.6	-2.7	-2.3	-0.7	-1.3
Primary Biliary Cirrhosis	1.6	2.2	6.2	1.2	1.2	1.4	-1.8	2.5	1.1	0.3	1.5
Type 2 Diabetes (T2D) (2018)	1.6	3.0	6.1	-1.7	-2.2	-2.0	-1.1	-1.4	-2.5	-1.2	-1.3
Prospective memory result	1.6	2.0	3.9	1.3	1.8	1.7	-1.9	2.0	0.6	-0.5	0.0
Mean time to correctly identify matches	1.6	3.1	6.7	-2.3	-2.2	-2.6	1.1	-1.6	0.3	1.6	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	6.9	-0.8	-0.4	-0.8	1.3	0.5	1.2	2.6	1.7
Fractured/broken bones in last 5 years	1.6	2.0	3.9	-1.5	-0.9	-1.1	1.4	-0.1	1.5	2.0	1.9
Cholesterol lowering medication	1.6	2.4	4.5	1.9	2.1	2.1	0.2	1.8	1.6	0.7	0.4
Sensitivity / hurt feelings	1.5	2.5	4.4	-1.9	-2.0	-1.6	0.7	-2.1	-1.4	-1.2	-1.2
Current tobacco smoking	1.5	2.4	5.8	2.0	2.4	2.2	0.4	0.8	2.0	0.0	0.4
Medication: Seretide 50 evohaler	1.5	1.7	3.1	-1.2	-1.0	-1.5	1.8	-1.5	0.5	1.3	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	6.7	1.7	1.3	1.5	-2.0	1.9	-1.2	-1.6	-2.6
Asthma (self-reported)	1.5	2.9	5.8	-2.1	-2.4	-2.4	1.3	-2.1	-1.0	0.3	0.1
Alcohol usually taken with meals	1.4	2.3	5.3	-1.5	-1.7	-1.4	-1.0	-0.3	-2.3	-1.2	-1.8
Nervous feelings	1.4	2.6	6.3	-2.5	-2.5	-2.5	-0.1	-0.4	-1.3	0.5	0.4
Mouth/teeth dental problems	1.4	2.2	5.0	1.5	1.4	1.7	-0.5	-0.7	-0.5	-2.1	-2.2
Asthma	1.4	2.8	6.2	-2.1	-2.5	-2.5	1.1	-1.8	-0.9	0.6	0.5
Mouth/teeth dental problems: Loose teeth	1.4	1.7	3.4	1.8	1.9	1.7	-0.8	1.3	0.9	-0.8	0.2
Osteoporosis (self-reported)	1.4	1.7	3.2	-1.7	-1.8	-1.7	-0.0	-1.6	-1.2	-0.3	-0.5
Smoking status: Current	1.4	2.2	5.0	1.8	2.2	1.9	0.3	0.8	2.0	0.4	0.6
Bipolar Disorder (2018)	1.3	2.1	5.8	1.3	1.3	1.1	-0.6	1.8	1.6	0.6	2.4
Neuroticism score	1.3	2.6	6.1	-2.1	-2.5	-2.3	1.0	-1.4	-0.4	0.1	1.5
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.5	-1.3	-1.3	-1.3	-0.4	-1.1	-1.9	-0.8	-1.2
Medication: Gliclazide	1.3	1.4	2.7	-1.4	-1.1	-1.4	1.6	-1.2	-0.7	1.3	0.3
Breast Cancer	1.2	2.9	6.8	2.1	2.6	2.3	-0.1	1.9	1.6	0.4	-0.5
Heel T-Score	1.2	9.3	20.3	-4.3	-4.5	-4.5	-0.7	-1.7	-3.5	0.0	-0.6
Neuroticism	1.2	3.0	7.3	-2.4	-2.7	-2.7	0.3	-1.2	-1.4	0.3	0.3
Had other major operations	1.2	1.5	4.6	1.1	1.3	1.5	0.1	0.9	2.1	0.1	1.2
Financial difficulties in last 2 years	1.2	1.6	3.8	1.1	0.8	1.0	-1.9	0.6	-0.8	-1.9	-1.1
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	2.8	-1.4	-1.7	-1.4	1.4	-1.6	-1.0	-0.5	-0.2
Lung cancer (father)	1.2	1.4	3.6	-1.9	-1.8	-1.8	-0.3	0.0	-1.2	-0.3	0.2
Length of working week for main job	1.2	1.3	3.4	-1.3	-1.5	-1.2	-1.1	-0.3	-1.9	-0.4	-0.7
Glaucoma (self-reported)	1.2	1.4	2.4	1.4	1.5	1.4	1.4	-0.3	1.6	0.2	0.7
Arm fat-free mass (right)	1.2	6.0	12.5	2.0	2.1	1.6	0.7	3.5	2.5	3.5	2.3
Comparative body size at age 10	1.2	3.2	6.0	-2.0	-2.0	-2.0	1.1	-2.4	-1.4	0.3	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	3.5	1.1	1.2	1.1	-0.1	1.9	1.0	1.3	1.1
Angina (self-reported)	1.2	1.5	4.2	0.8	0.9	0.8	1.0	0.9	2.0	1.4	1.5
Myopia	1.2	1.7	4.2	2.0	1.9	2.0	-0.2	0.8	0.8	-0.5	0.7
Respiratory disease	1.1	2.5	5.1	-2.1	-2.2	-2.1	0.8	-2.1	-1.0	0.0	0.2
Pack years adult smoking proportion	1.1	1.7	4.3	1.4	2.0	2.1	-0.2	-0.3	0.8	-1.5	-0.6
Maternal smoking around birth	1.1	1.6	4.8	-2.2	-1.7	-1.7	-0.8	-0.5	-1.1	-0.1	-0.6
Medication: Atenolol	1.1	1.3	2.8	1.1	1.3	1.5	-0.8	1.3	0.6	-1.7	0.4
Time employed in main current job	1.1	1.3	4.0	-0.8	-0.9	-0.5	-0.1	-2.0	-1.2	-1.4	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	4.0	-0.2	-1.2	-0.6	1.9	-2.0	0.2	-0.4	-0.5
Pulse wave Arterial Stiffness index	1.1	1.3	5.2	1.0	0.7	0.6	-2.3	1.6	-0.5	-0.1	-0.5
Peak expiratory flow (PEF)	1.1	2.7	5.2	-2.1	-2.0	-1.8	-1.0	-0.8	-2.3	-1.5	-0.1
Qualifications: College or University degree	1.1	3.6	8.0	-2.5	-2.8	-2.5	1.9	-1.8	-1.2	0.7	0.2
Arm predicted mass (right)	1.1	5.9	14.2	1.9	2.0	1.4	0.2	3.8	2.3	3.6	2.2
Supplements: Calcium	1.1	1.2	5.1	-0.5	-0.8	-0.8	1.8	-2.2	0.0	-0.4	-0.2
Heart disease (siblings)	1.1	1.4	3.4	-0.5	-0.2	-0.4	1.8	-0.5	1.8	1.8	1.0
Worry (Nagel 2018)	1.0	2.2	4.9	-2.1	-2.2	-2.0	-0.7	-0.4	-1.7	-0.3	0.1
Major Depression (MDD)	1.0	1.2	2.8	0.9	0.9	0.8	-0.1	1.7	1.3	0.9	1.5
LDL Cholesterol	1.0	1.6	6.4	-0.1	-0.2	-0.5	-0.7	1.5	0.7	1.7	2.5
Height	1.0	18.8	33.5	5.8	5.2	5.2	-5.0	5.8	1.6	-1.5	0.5
Lung FEV1/FVC ratio	1.0	5.1	10.8	-2.9	-2.4	-2.6	1.3	-3.3	-2.3	-0.4	-1.3
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.0	-1.6	-1.7	-1.5	-0.1	-0.7	-1.2	0.2	-0.7
Angina	1.0	1.3	3.3	0.9	1.0	0.9	0.7	1.0	1.8	1.4	1.2
Supplements: Glucosamine	1.0	1.3	3.0	-0.8	-1.1	-0.7	0.4	-1.7	-1.0	-1.4	-1.5
Ever highly irritable/argumentative for 2 days	1.0	1.3	3.5	-0.5	-0.7	-0.9	1.1	0.5	1.2	1.4	1.9
Age at last live birth	1.0	1.5	2.9	-1.4	-1.7	-1.5	0.4	-1.2	-1.6	0.2	-0.8
Eye problems/disorders: Cataract	1.0	1.2	2.0	1.2	1.4	1.2	0.4	1.4	1.1	1.1	0.1
Age started oral contraceptive pill	1.0	1.3	3.8	-0.6	-0.4	-0.6	-1.9	0.1	-1.9	-0.3	-1.5
Ever depressed for a whole week	1.0	1.3	4.6	-0.4	-0.6	-0.9	1.4	-0.1	0.7	2.1	1.3
Alcohol drinker status: Previous	1.0	1.1	3.3	1.0	1.1	1.1	-0.3	-0.7	-0.9	-1.8	-0.8
Pack years of smoking	1.0	1.4	3.3	1.1	1.8	1.8	-0.3	-0.5	0.8	-1.6	-0.7
Crohns Disease (2012)	0.9	1.4	5.0	-1.4	-1.0	-0.8	0.8	-2.2	-0.7	-1.3	-0.5
Chronotype (morning person)	0.9	2.1	4.8	-2.2	-2.1	-2.1	0.8	-1.4	-0.8	0.5	0.1
Average weekly spirits intake	0.9	1.1	2.2	1.5	1.3	1.2	-0.3	1.3	0.9	0.4	-0.6
Townsend deprivation index at recruitment	0.9	1.2	2.6	1.6	1.6	1.4	-0.2	0.5	1.2	0.7	0.3
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	2.2	-1.5	-1.5	-1.4	-0.7	-0.0	-1.0	0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	4.8	-1.3	-1.4	-1.7	-0.0	-0.9	-2.1	0.5	-2.2
Multivitamins +/- minerals	0.9	1.2	4.1	0.9	1.2	1.2	1.0	0.5	2.0	0.8	-0.2
Waist circumference	0.9	3.2	6.2	2.5	2.5	2.3	0.0	1.5	1.8	1.5	0.2
Exposure to tobacco smoke at home	0.9	1.0	2.3	0.6	1.1	1.1	1.4	-0.6	1.5	0.1	0.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.2	-0.9	-0.8	-0.6	-1.7	1.1	-0.5	-0.4	1.8
Number of full brothers	0.9	1.1	2.9	-0.6	-0.8	-1.1	0.9	-0.9	0.0	1.5	1.7
Pulse wave peak to peak time	0.9	1.0	4.0	-0.9	-0.7	-0.5	2.0	-1.6	0.4	-0.2	0.5
Smoking status: Previous	0.9	1.4	2.8	-1.0	-1.2	-1.1	-0.2	-1.7	-1.5	-1.5	-0.5
Back pain experienced in last month	0.9	1.3	5.0	-0.4	-0.7	-0.8	1.2	-0.4	0.9	1.2	2.2
Arm fat-free mass (left)	0.9	4.7	13.5	1.6	1.5	1.0	0.7	3.0	2.1	3.7	2.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.0	3.3	-0.4	-0.6	-0.7	0.8	0.1	0.8	1.8	1.6
Impedance of whole body	0.9	4.5	19.0	0.7	0.5	1.0	-2.7	-0.8	-1.4	-4.4	-2.3
Arm predicted mass (left)	0.9	4.5	12.0	1.6	1.7	1.1	0.5	3.0	2.0	3.5	1.9
Schizophrenia vs Biploar Disorder	0.8	1.1	2.1	1.2	1.4	1.4	0.2	1.0	1.3	0.6	0.6
Diabetes (mother)	0.8	1.0	2.4	1.2	1.2	1.3	0.8	0.0	1.6	0.5	0.2
Taking other prescription medications	0.8	1.2	2.2	1.3	1.3	1.1	0.4	1.5	1.4	0.7	0.9
Medication: Simvastatin	0.8	1.1	2.7	1.6	1.4	1.2	-0.6	1.2	0.5	0.8	-0.1
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.6	-1.3	-1.2	-1.2	1.3	-0.9	0.6	0.8	0.2
Medication: Allopurinol	0.8	1.1	2.7	0.7	1.0	1.0	1.6	-1.0	1.4	-0.7	0.4
Medication: Omeprazole	0.8	0.9	2.5	-0.2	-0.4	-0.4	1.1	0.0	1.0	1.4	1.6
Heart disease (mother)	0.8	1.0	3.8	-0.5	-0.3	-0.6	1.9	-1.4	0.2	1.1	0.7
Number of full sisters	0.8	0.9	2.2	-1.0	-0.8	-1.0	0.1	0.5	-0.5	1.5	1.4
Ever had bowel cancer screening	0.8	0.9	3.8	-0.2	-0.5	-0.5	-2.0	1.2	-0.2	0.8	1.0
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.5	-0.8	-1.3	-1.0	-0.2	-1.6	-1.1	-1.1	-0.4
Diastolic blood pressure, automated reading	0.8	2.5	4.9	1.9	2.1	2.2	-1.3	0.5	0.3	-1.5	-1.8
Vascular/heart problems diagnosed by doctor	0.8	2.1	5.8	-1.0	-1.3	-1.0	-1.8	-0.3	-2.4	-1.2	-1.6
Depressed Affect (Nagel 2018)	0.7	1.4	3.7	-1.2	-1.9	-1.6	-0.1	-1.0	-1.2	-1.0	-0.4
Depression (Nagel 2018)	0.7	1.1	2.7	-0.7	-1.2	-1.0	-0.8	-0.8	-1.3	-1.6	-0.5
Alzheimer’s Disease (including proxy)	0.7	1.0	6.9	-0.2	0.2	-0.2	-0.3	0.1	0.9	0.3	2.6
Ulcerative Colitis	0.7	1.0	1.9	-1.1	-0.9	-1.0	1.4	-1.0	0.4	1.1	0.7
Supplements: Zinc	0.7	0.8	1.7	1.3	1.1	1.2	-0.0	0.7	1.0	-0.4	-0.4
Fed-up feelings	0.7	1.3	3.1	-1.4	-1.8	-1.5	-0.3	-1.1	-0.9	-0.9	0.6
Trunk fat mass	0.7	2.9	6.3	2.5	2.5	2.5	-0.8	1.3	0.9	0.2	-1.0
Number of incorrect matches in round	0.7	1.2	4.0	0.4	0.3	0.1	-2.0	1.2	-0.7	0.9	-1.5
Hearing difficulty/problems with background noise	0.7	1.1	3.0	0.6	0.8	0.9	0.6	0.4	1.7	0.2	1.7
Hair/balding pattern: Pattern 2	0.7	0.8	1.7	1.0	1.3	1.3	0.1	-0.5	0.4	-1.2	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	3.8	-1.4	-1.7	-2.0	0.2	-0.7	-1.3	1.0	-0.9
Father’s age at death	0.7	0.9	3.6	0.1	-0.3	-0.3	1.9	-0.3	1.3	1.1	0.8
Worrier / anxious feelings	0.7	1.2	2.4	-1.6	-1.5	-1.4	0.7	-0.8	-0.3	-0.3	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.2	-0.9	-1.2	-1.0	-1.1	-0.8	-1.5	-1.0	0.2
Falls in the last year	0.7	0.9	2.2	0.7	0.6	1.0	-1.4	1.5	-0.6	-0.9	-0.5
Number of live births	0.7	1.0	3.4	0.8	0.9	1.0	-1.3	0.2	-0.3	-1.8	-0.5
Medication: Paracetamol	0.7	1.1	2.4	1.1	1.4	1.5	-1.0	0.9	0.8	-0.7	-0.5
Headache pain in last month	0.7	1.1	2.7	1.6	1.5	1.6	-0.3	0.1	0.2	-1.1	-0.5
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.8	0.3	0.7	0.4	-1.7	1.7	-0.4	0.4	0.5
Illnesses of siblings: Diabetes	0.7	0.9	2.0	-1.2	-1.4	-1.1	0.8	-0.5	-0.5	1.1	0.4
Diabetes diagnosed by doctor	0.7	1.2	2.2	-1.2	-1.2	-1.1	-0.1	-1.5	-1.4	-0.8	-0.5
Whole body water mass	0.7	3.9	9.9	2.1	2.1	1.8	-0.1	3.1	1.6	2.3	1.2
Guilty feelings	0.7	1.1	2.8	-1.5	-1.3	-1.2	0.3	-1.7	-0.8	-0.4	-0.2
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.8	-1.4	-1.1	-1.1	-0.5	-0.7	-1.2	-0.1	-0.9
Number of operations (self-reported)	0.7	1.0	2.6	1.3	1.2	1.6	-0.6	0.7	1.1	-0.6	-0.4
Risk taking	0.7	1.0	2.9	0.8	0.7	0.8	-0.4	1.5	0.8	0.6	1.7
Crohns Disease (2017)	0.6	1.4	3.3	-1.3	-0.9	-0.4	-0.2	-1.8	-1.0	-1.8	-0.8
Ulcerative Colitis (UC)	0.6	1.0	2.0	-1.4	-1.2	-1.2	0.8	-1.4	-0.4	0.0	0.7
HDL Cholesterol	0.6	1.0	1.7	1.1	1.1	1.3	0.5	0.5	1.3	1.0	0.8
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.4	-0.5	-1.1	-1.0	1.6	-1.2	0.2	-0.1	0.5
Vitamin and mineral supplements	0.6	0.7	2.8	0.3	0.5	0.4	-1.2	-0.3	-1.0	-1.7	-0.4
Medication: Co-codamol	0.6	0.7	2.3	-0.0	0.1	0.1	-1.5	0.1	-1.2	-1.2	0.1
Medication: Metformin	0.6	0.8	1.6	-1.3	-1.2	-1.1	0.6	-1.1	-0.6	-0.1	-0.2
Leg fat-free mass (left)	0.6	3.1	5.9	2.4	2.4	2.3	-0.3	2.4	1.1	0.9	-0.1
Trunk fat percentage	0.6	2.5	5.7	2.2	2.2	2.4	-0.9	0.6	0.6	-0.7	-1.6
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.7	-1.0	-1.3	-1.2	0.3	-0.3	0.0	0.8	-0.3
Leg predicted mass (left)	0.6	3.2	6.2	2.4	2.5	2.4	-0.4	2.5	1.0	0.9	-0.1
Illnesses of siblings	0.6	0.8	3.1	-0.0	-0.1	-0.1	-0.6	-0.1	-1.4	-1.1	-1.8
Trunk fat-free mass	0.6	3.6	8.6	1.8	1.8	1.3	0.3	2.9	1.7	2.6	1.4
Trunk predicted mass	0.6	3.6	8.7	1.8	1.8	1.3	0.3	3.0	1.7	2.6	1.4
Standing height	0.6	5.5	13.2	2.7	2.5	2.3	-3.2	3.6	0.1	-1.0	-0.4
Loud music exposure frequency	0.6	0.6	1.4	-1.2	-1.1	-1.1	0.0	-0.5	-0.0	0.4	0.9
Blood clot in the leg (DVT)	0.6	0.7	1.9	-1.1	-1.0	-0.9	1.0	-1.4	-0.2	-0.0	-0.1
Medication: Amlodipine	0.6	0.8	2.4	0.9	0.8	1.0	-1.0	-0.5	-0.5	-1.5	-0.4
Age at first live birth	0.6	1.1	2.6	-1.3	-1.6	-1.5	0.4	-0.5	-1.2	0.7	0.2
Eye problems/disorders: None of the above	0.6	0.7	1.3	-0.8	-1.1	-0.9	-0.7	-0.7	-1.0	-0.9	0.4
Whole body fat mass	0.6	2.3	5.1	2.2	2.3	2.2	-0.4	1.2	1.0	0.5	-0.8
Overall health rating	0.6	1.3	3.2	0.9	1.1	1.0	0.9	0.6	1.8	0.6	1.6
Chest pain or discomfort	0.6	0.8	1.4	-1.1	-1.1	-1.2	0.8	-0.9	-0.3	0.6	0.8
Family relationship satisfaction	0.6	0.8	2.3	-0.4	-0.6	-0.6	-0.3	-1.5	-1.3	-0.6	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.5	-0.6	-0.3	-0.1	-0.3	-0.0	-1.0	-1.1	-1.6
Whole body fat-free mass	0.6	3.7	9.0	2.1	2.1	1.8	-0.0	3.0	1.6	2.2	0.9
Leg fat-free mass (right)	0.6	3.3	7.1	2.4	2.4	2.4	-0.7	2.7	0.9	0.9	0.1
Mineral and other dietary supplements	0.6	0.9	1.5	1.1	1.1	1.0	0.2	1.1	0.9	0.3	1.2
Leg predicted mass (right)	0.6	3.3	7.2	2.4	2.4	2.4	-0.7	2.7	0.9	0.9	0.1
Hearing aid user	0.6	0.6	2.7	-0.2	0.1	-0.1	-1.6	0.3	-1.0	-1.1	0.1
Mother’s age at death	0.6	0.8	1.5	1.2	1.2	1.0	-0.9	1.1	-0.4	0.3	-0.4
Financial situation satisfaction	0.6	0.7	2.2	-0.6	-0.4	-0.4	0.1	-1.0	-1.1	-0.8	-1.5
Eye problems/disorders: Glaucoma	0.6	0.8	2.8	0.7	0.5	0.6	1.7	-1.2	1.0	-0.0	0.1
Basal metabolic rate	0.6	3.4	7.6	2.1	2.1	1.9	0.0	2.8	1.5	2.0	0.8
Irritability	0.6	1.1	3.2	-1.1	-1.4	-1.3	0.1	-0.0	0.2	0.4	1.8
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	2.0	-1.0	-0.9	-0.7	1.3	-1.4	0.1	-0.1	0.1
Irritable Bowel Disease (IBD)	0.5	1.2	3.1	-1.6	-1.1	-0.9	0.2	-1.8	-0.7	-1.0	0.3
Body Mass Index (BMI) (2010)	0.5	0.7	1.7	-1.0	-0.6	-0.9	1.2	-1.3	0.0	0.2	0.3
Blood Eosinophil Count	0.5	3.5	7.9	2.0	2.5	2.5	-0.9	2.8	1.8	-0.2	0.2
Ever had hysterectomy (womb removed)	0.5	0.6	2.7	-0.4	-0.6	-0.4	-1.6	0.5	-0.9	-0.3	0.2
Systolic blood pressure, automated reading	0.5	1.4	3.7	0.3	0.8	0.9	-1.8	-0.2	-0.7	-1.9	-1.5
Average weekly fortified wine intake	0.5	0.6	1.8	0.3	0.1	0.5	-1.3	0.1	-0.7	-1.2	-0.9
Qualifications: CSEs or equivalent	0.5	0.7	2.3	0.2	0.5	0.4	-1.5	1.3	-0.0	-0.8	-0.4
Serious illness, injury or assault to yourself	0.5	0.6	1.9	-0.7	-0.1	0.0	1.4	-1.1	0.3	-0.4	-0.8
High blood pressure	0.5	1.4	3.5	0.9	1.1	0.8	1.5	0.3	1.9	1.0	1.4
Forced vital capacity (FVC)	0.5	2.0	6.1	1.8	1.2	1.4	-1.4	2.5	0.7	-0.7	1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.6	-0.3	-0.5	-0.7	1.6	-0.7	0.5	1.0	0.1
Hair/balding pattern: Pattern 4	0.5	1.2	2.6	-1.4	-1.5	-1.6	0.5	-0.6	-0.5	0.9	0.9
Birth weight of first child	0.5	0.9	2.4	1.0	1.0	1.1	-1.5	0.5	0.0	-1.2	-0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	3.0	0.1	0.4	0.6	0.4	-0.6	-0.7	-1.3	-1.7
High blood pressure (siblings)	0.5	0.8	1.3	1.1	1.0	1.0	-0.9	0.8	0.7	-0.8	0.5
Medication: Ibuprofen	0.5	0.7	1.3	-1.0	-0.6	-0.6	0.0	-0.7	-1.2	-1.2	-0.5
Leg pain on walking	0.5	0.6	1.8	0.7	0.6	0.5	-1.4	1.1	-0.7	0.1	0.1
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.0	0.5	0.0	0.1	1.4	-0.5	1.1	0.6	0.4
Friendships satisfaction	0.5	0.6	0.9	-0.7	-0.9	-1.0	0.9	-0.7	0.3	0.7	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	2.6	-0.6	-0.2	-0.2	-1.6	0.5	-1.0	-0.0	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.9	0.1	0.2	0.3	0.3	-1.2	-0.1	-1.4	-0.8
Alzheimer’s Disease (in mother)	0.4	0.5	1.5	-0.5	-0.0	0.0	-0.8	-0.8	-0.3	-1.2	0.8
Prostate Cancer	0.4	0.6	2.5	-0.5	-0.3	-0.4	1.2	-1.6	0.3	0.3	-0.0
Coronary Artery Disease (CAD)	0.4	0.4	1.1	-0.4	-0.6	-0.4	1.0	-1.0	0.0	0.2	-0.8
Blood Platelet Count	0.4	4.8	12.0	-2.7	-2.1	-2.8	2.1	-0.9	-0.1	3.5	1.4
Systolic Blood Pressure	0.4	1.9	7.5	1.1	1.6	1.7	-0.8	0.0	0.3	-2.7	-0.5
Relative age of first facial hair	0.4	0.8	4.0	0.2	0.1	0.2	-0.6	-0.3	-1.0	-2.0	-1.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.0	-0.9	-1.0	-0.8	-0.0	-0.8	-0.9	-0.3	-0.6
Medication for hormone replacement therapy	0.4	0.4	1.2	-0.4	-0.3	-0.2	1.1	-0.7	-0.2	0.2	-1.1
Diabetes (father)	0.4	0.6	1.6	0.2	0.8	0.6	-0.9	0.7	0.7	0.1	1.3
Severe depression (siblings)	0.4	0.5	1.8	-0.1	0.2	-0.1	-0.0	0.9	0.5	1.3	0.9
Had menopause	0.4	0.5	1.7	-1.3	-0.8	-0.9	-0.1	-0.6	0.1	0.6	0.2
Heart attack	0.4	0.5	1.3	-0.1	-0.1	0.0	1.1	-0.6	1.0	0.6	0.9
Pulse rate	0.4	0.7	4.0	0.1	0.2	0.0	2.0	-0.7	0.7	0.4	0.7
Tense / ‘highly strung’	0.4	0.7	1.7	-0.5	-0.5	-0.4	1.3	-1.2	0.3	0.1	1.2
Exposure to tobacco smoke outside home	0.4	0.5	3.1	-0.2	-0.0	-0.3	-0.3	0.5	-0.1	1.7	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	0.8	-0.7	-0.9	-0.8	-0.7	0.7	-0.9	-0.1	0.4
Neck or shoulder pain in last month	0.4	0.5	1.9	-0.4	-0.3	-0.6	1.2	-0.4	-0.1	0.5	1.4
Arm fat percentage (left)	0.4	1.5	3.3	1.5	1.6	1.8	-0.2	-0.2	0.2	-0.5	-1.7
Average weekly red wine intake	0.4	0.6	1.6	-0.4	-0.3	-0.5	-1.0	-0.7	-1.3	-1.0	-0.5
Mood swings	0.4	0.7	1.9	-0.1	-0.4	-0.1	1.3	-0.2	1.1	0.1	1.4
Arm fat mass (left)	0.4	1.7	3.7	1.8	1.9	1.9	-0.0	0.9	0.9	0.7	-0.7
Number of self-reported non-cancer illnesses	0.4	0.7	1.4	0.7	0.8	0.6	0.2	0.9	1.2	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.9	-0.1	-0.0	-0.3	0.4	-0.4	0.6	0.6	1.7
Commuting to job workplace: Public transport	0.4	0.5	1.6	-0.0	0.1	0.3	-1.3	-0.1	-0.4	-1.2	-0.6
Medication: Blood pressure	0.4	0.8	1.5	1.0	1.0	1.0	0.5	0.6	1.2	-0.0	1.2
Medication: Bendroflumethiazide	0.4	0.6	1.9	-0.1	-0.0	-0.3	1.4	-0.9	0.7	0.3	1.2
Average weekly beer plus cider intake	0.4	0.6	1.8	0.2	0.4	0.3	0.6	0.5	1.3	0.8	1.3
Commuting to job workplace: Cycle	0.4	0.4	1.0	-0.9	-1.0	-0.8	0.4	-0.4	-0.6	0.1	-0.6
Pain experienced in last month	0.4	0.6	1.9	-1.4	-1.1	-1.0	0.4	-0.4	-0.1	0.7	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.3	-0.1	-0.0	0.0	1.1	-0.5	1.1	0.7	1.1
Rheumatoid Arthritis	0.3	0.4	0.9	0.7	0.7	0.7	-0.9	0.5	-0.6	-0.6	-0.6
Cardiovascular Disease	0.3	1.0	3.5	0.8	0.9	0.7	-0.8	1.9	1.1	0.5	0.9
Relative age voice broke	0.3	0.5	1.2	0.8	0.6	0.6	-1.1	0.7	-0.1	-1.0	-0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.8	-0.6	-0.5	-0.4	-0.3	-0.9	0.2	-0.9	0.8
Past tobacco smoking	0.3	0.6	2.4	0.6	0.4	0.4	-0.4	1.6	0.4	1.3	0.1
Qualifications: None of the above	0.3	0.5	1.6	0.3	0.0	-0.2	-0.6	0.5	1.0	1.3	1.1
Pain all over the body in last month	0.3	0.3	0.7	-0.5	-0.6	-0.6	-0.7	-0.4	-0.3	-0.5	0.8
Diabetes (self-reported)	0.3	0.5	1.0	-0.8	-1.0	-0.8	-0.2	-0.7	-0.9	-0.3	-0.5
Medication: Ramipril	0.3	0.4	0.9	-0.8	-0.6	-0.6	0.3	-0.1	0.7	0.9	0.7
Weight	0.3	1.3	2.2	1.4	1.5	1.3	-0.1	1.4	0.7	1.4	-0.3
Happiness	0.3	0.3	1.2	0.1	-0.5	-0.5	-0.8	-0.3	-1.1	-0.1	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.4	-0.5	-0.1	-0.1	0.4	-0.8	-0.7	-1.2	-0.6
Arm fat mass (right)	0.3	1.2	2.6	1.6	1.6	1.6	0.0	0.6	0.7	0.8	-0.7
Gout (self-reported)	0.3	0.4	1.7	0.4	0.4	0.5	0.5	-0.8	-0.0	-1.3	-0.1
Birth weight	0.3	0.7	3.1	-0.0	0.5	0.3	0.2	1.2	0.7	1.8	0.5
Forced vital capacity (FVC), Best measure	0.3	1.3	5.9	0.9	0.6	0.6	-1.3	2.4	0.2	0.0	1.0
Body fat percentage	0.3	1.2	2.9	1.5	1.7	1.7	-0.2	0.2	0.6	0.0	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.2	-0.6	-0.3	-0.5	1.1	-1.0	0.4	0.4	-0.2
Leg fat mass (right)	0.3	1.3	2.4	1.5	1.6	1.4	0.4	0.8	1.1	1.4	-0.4
Alcohol intake frequency.	0.3	0.7	1.2	0.7	1.0	1.0	1.0	-0.7	-0.0	0.2	-1.1
Hypertension (Self-reported)	0.3	0.9	2.5	0.8	0.9	0.7	1.0	0.4	1.6	0.7	1.2
Qualifications: nursing, teaching	0.3	0.5	1.9	-0.2	-0.4	-0.0	0.3	-1.0	-0.7	-1.4	-0.2
Osteoarthritis (self-reported)	0.3	0.4	1.1	-0.6	-0.6	-0.7	0.3	-1.1	-0.5	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	1.1	-0.9	-1.0	-1.1	-0.2	-0.3	-0.9	0.0	0.6
Ever taken oral contraceptive pill	0.3	0.3	0.9	-0.2	-0.5	-0.5	0.8	-0.6	-0.3	0.6	-1.0
Medication: Lisinopril	0.3	0.4	1.2	-0.3	-0.1	-0.2	0.9	-0.1	1.0	0.4	1.1
Medication: Atorvastatin	0.3	0.4	0.8	0.5	0.4	0.6	-0.9	0.4	-0.1	-0.4	-0.9
Leg fat mass (left)	0.3	1.3	2.2	1.4	1.5	1.3	0.2	1.0	1.0	1.5	-0.2
Reaction Time	0.2	0.5	1.0	-0.9	-0.9	-1.0	0.6	-0.8	0.3	0.3	0.1
Ovarian Cancer	0.2	0.3	0.7	-0.5	-0.5	-0.5	-0.1	-0.2	-0.8	-0.4	-0.7
Age at First Birth	0.2	0.3	0.8	0.6	0.5	0.4	0.5	0.3	0.4	0.9	0.3
HbA1C	0.2	0.3	1.1	0.1	0.3	0.3	-0.3	0.3	0.2	-1.0	0.8
BMI	0.2	1.4	4.6	-0.8	-0.6	-0.7	2.1	-0.8	0.5	2.0	-0.3
Hearing difficulty/problems: Yes	0.2	0.3	1.4	0.4	0.5	0.4	0.1	0.0	1.2	0.3	0.7
Sitting height	0.2	1.4	4.0	-0.3	-0.2	-0.2	-0.2	-0.8	-1.6	-1.9	-2.0
Body mass index (BMI)	0.2	0.8	4.1	0.2	0.3	0.3	1.4	-0.1	0.7	2.0	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.3	-0.7	-0.5	-0.4	-0.3	-0.4	-0.2	-1.1	0.1
Arm fat percentage (right)	0.2	1.0	2.7	1.1	1.2	1.4	0.0	-0.6	-0.1	-0.3	-1.6
Hip circumference	0.2	0.7	3.0	-0.1	-0.0	0.1	-0.7	-0.9	-1.1	-0.4	-1.7
Depression (self-reported)	0.2	0.2	0.8	-0.3	-0.4	-0.3	0.8	0.1	-0.1	0.9	0.2
Medication: Lansoprazole	0.2	0.3	1.1	-0.3	0.0	-0.1	-0.4	0.7	0.1	1.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.9	-0.3	-0.7	-0.5	1.0	0.2	0.1	0.3	0.4
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.9	-0.3	-0.1	-0.2	-0.6	-0.7	-0.4	-0.4	-1.0
Leg fat percentage (right)	0.2	0.7	2.0	0.6	0.7	0.5	1.1	-0.3	1.0	1.4	-0.2
Wheeze or whistling in the chest in last year	0.2	0.4	1.3	0.2	-0.2	-0.4	0.8	-0.0	0.4	1.0	1.1
Shortness of breath walking on level ground	0.2	0.3	1.1	-0.5	-0.6	-0.5	-0.2	0.2	0.0	-0.6	1.0
Emphysema/chronic bronchitis	0.2	0.2	0.8	-0.3	-0.1	-0.4	-0.9	0.5	0.2	0.2	0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	0.1	-0.3	-0.3	0.5	0.1	0.4	0.7	1.0
Migraine (self-reported)	0.2	0.3	0.9	0.1	-0.0	-0.2	0.7	-0.4	-0.5	0.6	-1.0
Pulse rate, automated reading	0.2	0.6	2.6	-0.0	0.1	-0.1	1.6	-0.5	0.8	1.1	-0.5
Comparative height size at age 10	0.2	1.4	4.8	1.1	0.5	0.4	-2.2	2.0	-0.2	0.5	-0.5
Breast cancer (self-reported)	0.2	0.2	0.8	-0.6	-0.4	-0.2	-0.9	-0.4	0.2	-0.1	0.0
Average weekly champagne plus white wine intake	0.2	0.3	1.0	-0.3	-0.7	-0.3	-0.1	-0.4	-0.6	-0.6	-1.0
Miserableness	0.2	0.3	0.7	-0.4	-0.8	-0.8	0.6	-0.2	0.0	0.3	0.7
Alcohol drinker status: Never	0.2	0.2	0.4	-0.6	-0.1	-0.4	0.4	-0.6	-0.6	0.5	-0.2
Ever smoked	0.2	0.4	0.9	-0.4	0.1	0.0	0.8	-0.9	0.6	-0.7	0.8
Leg fat percentage (left)	0.2	0.7	3.1	0.5	0.7	0.4	0.9	-0.1	1.0	1.8	0.1
Fasting Glucose	0.1	0.1	0.4	0.4	-0.2	0.1	-0.1	-0.0	0.2	-0.6	0.5
Triglycerides	0.1	0.1	0.3	-0.2	-0.4	-0.5	-0.4	0.1	-0.6	-0.0	-0.2
Blood White Count	0.1	0.6	2.2	-1.0	-0.2	-0.6	0.1	0.6	0.8	1.5	0.5
Smoking Status	0.1	0.3	0.8	0.6	0.9	0.7	0.1	-0.3	0.5	-0.5	-0.3
Hair Pigment	0.1	2.8	9.5	0.6	1.0	0.9	-1.4	-1.6	-0.9	-2.5	-3.1
Tanning	0.1	1.4	3.7	0.6	0.9	0.7	0.7	1.9	1.6	1.2	1.0
Number of treatments/medications taken	0.1	0.2	0.7	0.2	0.1	0.1	0.8	-0.5	-0.2	0.0	-0.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	-0.5	0.2	0.0	0.2	0.2	0.1	-0.2	-0.5
Impedance of leg (right)	0.1	0.7	3.1	-0.2	-0.5	-0.5	-0.9	-0.7	-0.4	-1.8	-0.7
Age when periods started (menarche)	0.1	0.3	0.6	-0.6	-0.4	-0.6	-0.7	0.6	-0.8	0.2	-0.4
High blood pressure (mother)	0.1	0.1	0.4	-0.2	0.3	0.5	-0.1	-0.0	0.6	-0.2	-0.3
Impedance of leg (left)	0.1	0.6	2.7	-0.2	-0.4	-0.4	-1.3	-0.4	-0.3	-1.6	-0.3
Alcohol intake versus 10 years previously	0.1	0.1	0.4	-0.4	-0.5	-0.3	-0.3	-0.4	-0.1	-0.1	0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	0.9	0.2	-0.2	0.0	-0.8	0.9	-0.4	-0.6	0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.8	-0.1	-0.2	-0.1	0.3	0.0	-0.9	-0.1	-0.5
Medication: Cholesterol lowering	0.1	0.1	0.2	0.4	0.2	0.1	-0.1	-0.2	-0.2	0.5	-0.4
Illnesses of mother	0.1	0.2	0.6	0.2	-0.3	-0.2	-0.2	0.3	-0.8	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.5	-0.1	-0.3	-0.2	-0.9	1.2	-0.6	-0.1	0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.2	-0.3	0.0	0.2	0.4	-0.5	-0.1	-1.1	-0.4
Number of children fathered	0.1	0.2	0.5	-0.3	0.0	-0.2	0.7	-0.7	0.2	0.0	-0.3
Medication: Blood pressure	0.1	0.3	1.2	-0.2	-0.2	-0.4	0.0	0.4	0.4	1.1	0.7
Medication: Aspirin	0.1	0.1	0.8	-0.2	-0.0	-0.1	0.4	-0.9	0.0	0.1	0.1
Knee pain experienced in last month	0.1	0.2	0.7	-0.2	-0.3	-0.3	-0.2	-0.4	-0.8	-0.6	-0.2
Long-standing illness, disability or infirmity	0.1	0.2	0.4	-0.6	-0.5	-0.6	0.1	-0.5	-0.2	0.1	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.5	0.0	-0.1	-0.1	0.7	-0.4	0.2	-0.2	0.3
Medication: Aspirin	0.1	0.1	0.5	-0.4	-0.2	-0.2	-0.0	-0.7	-0.2	-0.2	0.2
Blood Red Count	0.0	0.3	1.2	-0.3	-0.8	-0.5	0.2	-0.3	-0.5	0.4	-1.1
Illnesses of father: Heart disease	0.0	0.1	0.2	-0.1	0.2	0.1	0.0	-0.5	0.1	0.4	0.0
Medication: Paracetamol	0.0	0.1	0.3	-0.2	0.2	0.2	-0.0	-0.0	0.3	-0.2	-0.5

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