[Hub]/) : Traits : Impedance of arm (left) :

chr1:153,493,615-155,910,830

Best TWAS P=2.02e-22 · Best GWAS P=2.87e-24 conditioned to 0.129

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere DCST2 0.45 0.10 lasso 6 0.16 6.6e-05 3.83 -7.8 9.5e-15 0.14 0.23 0.10 FALSE
2 GTEx Brain Nucleus accumbens basal ganglia DCST2 0.28 0.04 lasso 5 0.13 2.0e-04 -9.32 -7.9 3.2e-15 0.19 0.13 0.21 FALSE
3 GTEx Esophagus Mucosa MUC1 0.17 0.20 lasso 4 0.18 5.6e-12 6.06 5.4 5.8e-08 -0.28 1.00 0.00 FALSE
4 GTEx Skin Sun Exposed Lower leg ADAM15 0.14 0.09 lasso 4 0.08 6.1e-07 -9.32 9.2 2.2e-20 -0.08 0.72 0.25 FALSE
5 GTEx Thyroid DCST2 0.16 0.12 lasso 2 0.11 6.4e-09 3.83 -5.2 1.5e-07 0.14 0.99 0.00 FALSE
6 GTEx Whole Blood C1orf43 0.10 0.00 enet 37 0.00 2.8e-01 3.51 5.1 2.9e-07 -0.05 0.01 0.73 FALSE
7 YFS Blood GBA 0.04 0.01 bslmm 321 0.02 3.9e-08 -3.96 -5.2 1.9e-07 0.38 0.98 0.00 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma ADAM15 0.15 0.02 blup 49 0.08 1.4e-05 -10.14 7.2 4.2e-13 -0.29 0.00 0.91 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MUC1 0.04 0.01 enet 4 0.02 1.3e-03 6.06 5.5 3.6e-08 -0.18 0.04 0.03 TRUE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma THBS3 0.04 0.01 blup 25 0.03 3.1e-04 -1.83 -5.2 1.5e-07 0.64 0.05 0.53 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADAM15 0.09 0.00 blup 49 0.02 3.6e-02 3.63 7.5 4.3e-14 -0.24 0.01 0.12 FALSE
12 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma THBS3 0.04 0.02 enet 8 0.01 4.5e-02 -1.83 -5.7 1.5e-08 0.51 0.02 0.32 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma ADAM15 0.07 0.00 enet 12 0.04 6.1e-05 -10.14 5.2 2.3e-07 -0.19 0.00 0.90 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ZBTB7B 0.05 0.06 lasso 2 0.05 1.8e-06 -9.32 9.3 8.7e-21 -0.07 0.00 1.00 TRUE
15 The Cancer Genome Atlas Pancreatic Adenocarcinoma AQP10 0.12 0.01 blup 37 0.04 7.1e-03 3.13 -5.3 1.0e-07 -0.02 0.00 0.41 TRUE
16 The Cancer Genome Atlas Prostate Adenocarcinoma GBA 0.05 0.01 lasso 2 0.01 2.3e-02 -10.16 9.7 2.0e-22 -0.93 0.00 0.87 TRUE
17 The Cancer Genome Atlas Thyroid Carcinoma THBS3 0.14 0.03 enet 16 0.08 3.8e-08 0.28 -5.4 8.0e-08 0.69 0.00 0.99 FALSE