[Hub]/) : Traits : Impedance of arm (left) :

chr14:34,696,729-36,483,802

Best TWAS P=2.98e-11 · Best GWAS P=8.61e-12 conditioned to 0.000331

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM177A1 0.07 0.05 bslmm 383 0.04 7.3e-06 5.0 -5.9 4.0e-09 0.40 0.50 0.44 FALSE
2 GTEx Adipose Subcutaneous PPP2R3C 0.21 0.12 lasso 10 0.14 2.6e-11 5.5 -5.2 1.8e-07 0.34 0.94 0.06 FALSE
3 GTEx Artery Tibial RP11-85K15.2 0.06 0.01 lasso 6 0.02 2.1e-02 5.0 6.3 4.1e-10 -0.69 0.10 0.47 FALSE
4 GTEx Brain Cerebellum FAM177A1 0.13 0.04 lasso 3 0.04 1.9e-02 6.5 -6.6 3.0e-11 0.59 0.03 0.72 TRUE
5 GTEx Esophagus Mucosa SRP54 0.13 0.05 lasso 5 0.05 1.6e-04 5.5 -5.8 7.2e-09 0.40 0.08 0.84 FALSE
6 GTEx Lung RP11-85K15.2 0.12 0.08 lasso 6 0.06 4.4e-05 -6.1 5.4 6.2e-08 -0.81 0.18 0.80 FALSE
7 GTEx Nerve Tibial SRP54 0.16 0.02 enet 14 0.08 1.3e-06 1.4 5.4 7.4e-08 -0.73 0.03 0.96 FALSE
8 GTEx Nerve Tibial FAM177A1 0.23 0.07 enet 37 0.10 1.1e-07 6.5 -5.3 1.2e-07 0.50 0.03 0.97 FALSE
9 GTEx Testis FAM177A1 0.30 0.16 lasso 5 0.23 1.2e-10 3.6 5.5 3.6e-08 -0.50 0.18 0.82 FALSE
10 NTR Blood KIAA0391 0.05 0.05 lasso 10 0.05 2.4e-15 5.5 5.5 3.9e-08 -0.29 0.92 0.08 FALSE
11 YFS Blood KIAA0391 0.29 0.36 lasso 7 0.38 5.8e-132 5.5 5.4 5.2e-08 -0.35 0.92 0.08 FALSE