[Hub]/) : Traits : Impedance of arm (left) :

chr15:76,398,193-78,806,023

Best TWAS P=4.97e-19 · Best GWAS P=3.28e-17 conditioned to 0.0503

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HMG20A 0.06 0.03 enet 10 0.06 9.8e-08 -2.2 -5.2 2.2e-07 -0.67 0.13 0.86 FALSE
2 GTEx Adipose Subcutaneous HMG20A 0.16 0.09 lasso 8 0.09 1.4e-07 -2.2 -5.2 1.8e-07 -0.69 0.10 0.90 FALSE
3 GTEx Adipose Subcutaneous RP11-797A18.4 0.19 0.12 lasso 8 0.16 2.1e-13 -4.5 -6.9 4.4e-12 -0.79 0.78 0.22 FALSE
4 GTEx Adipose Visceral Omentum RP11-797A18.4 0.06 0.05 lasso 3 0.06 4.1e-04 7.6 -7.1 1.5e-12 -0.78 0.06 0.83 FALSE
5 GTEx Adrenal Gland RP11-797A18.4 0.13 0.04 enet 18 0.11 1.1e-04 -4.4 -6.5 5.8e-11 -0.75 0.04 0.79 FALSE
6 GTEx Artery Aorta RP11-797A18.4 0.13 0.11 enet 17 0.12 2.3e-07 -4.5 -6.6 5.1e-11 -0.76 0.18 0.81 FALSE
7 GTEx Artery Coronary RP11-797A18.3 0.12 0.03 lasso 10 0.01 1.1e-01 -4.4 -7.5 8.5e-14 -0.80 0.04 0.50 FALSE
8 GTEx Artery Tibial TSPAN3 0.14 0.07 lasso 5 0.10 1.6e-08 8.2 -8.9 5.0e-19 -0.82 0.02 0.98 TRUE
9 GTEx Artery Tibial LINGO1 0.08 0.04 lasso 5 0.03 2.7e-03 -5.4 -5.8 8.5e-09 -0.47 0.24 0.18 FALSE
10 GTEx Artery Tibial RP11-797A18.4 0.14 0.03 enet 25 0.09 2.3e-07 7.6 -7.7 1.3e-14 -0.66 0.06 0.94 FALSE
11 GTEx Brain Caudate basal ganglia PSTPIP1 0.22 0.12 lasso 9 0.13 1.4e-04 7.9 7.0 2.3e-12 0.80 0.03 0.92 FALSE
12 GTEx Brain Caudate basal ganglia RP11-797A18.4 0.21 0.14 lasso 5 0.12 2.9e-04 7.7 -7.6 2.7e-14 -0.81 0.08 0.83 FALSE
13 GTEx Brain Cerebellar Hemisphere RP11-797A18.3 0.14 0.03 lasso 6 0.02 7.9e-02 -1.9 -5.6 2.4e-08 -0.66 0.06 0.30 FALSE
14 GTEx Brain Cerebellar Hemisphere RP11-797A18.4 0.14 0.12 enet 10 0.12 6.4e-04 4.9 -6.6 4.8e-11 -0.75 0.06 0.63 FALSE
15 GTEx Brain Cerebellum HMG20A 0.14 0.03 enet 7 0.10 6.4e-04 7.9 -6.9 4.3e-12 -0.73 0.04 0.71 FALSE
16 GTEx Brain Cerebellum RP11-797A18.4 0.29 0.20 lasso 9 0.25 4.0e-08 7.9 -6.8 1.0e-11 -0.78 0.07 0.89 FALSE
17 GTEx Brain Cortex RP11-797A18.4 0.47 0.28 enet 14 0.34 3.3e-10 7.9 -7.4 1.2e-13 -0.81 0.03 0.97 FALSE
18 GTEx Brain Frontal Cortex BA9 RP11-797A18.4 0.35 0.35 lasso 5 0.35 4.8e-10 7.6 -7.4 1.3e-13 -0.79 0.19 0.81 FALSE
19 GTEx Brain Hypothalamus RP11-797A18.4 0.21 0.18 lasso 7 0.22 7.6e-06 7.9 -8.4 5.4e-17 -0.92 0.01 0.98 FALSE
20 GTEx Brain Nucleus accumbens basal ganglia RP11-797A18.4 0.12 0.22 lasso 1 0.17 3.1e-05 7.6 -7.6 2.8e-14 -0.80 0.07 0.68 FALSE
21 GTEx Brain Putamen basal ganglia RP11-797A18.4 0.27 0.06 lasso 5 0.06 1.7e-02 7.7 -7.2 7.2e-13 -0.77 0.03 0.44 FALSE
22 GTEx Cells EBV-transformed lymphocytes PSTPIP1 0.13 0.04 enet 13 0.10 4.0e-04 6.0 -7.1 1.0e-12 -0.73 0.08 0.75 FALSE
23 GTEx Cells EBV-transformed lymphocytes TSPAN3 0.26 0.14 lasso 6 0.12 8.2e-05 -6.3 -6.4 1.6e-10 -0.53 0.14 0.26 FALSE
24 GTEx Cells EBV-transformed lymphocytes RP11-797A18.4 0.16 0.08 lasso 6 0.14 2.7e-05 -4.4 -6.7 2.7e-11 -0.77 0.09 0.80 FALSE
25 GTEx Cells Transformed fibroblasts TSPAN3 0.17 0.16 lasso 3 0.17 1.7e-12 8.2 -7.4 1.4e-13 -0.84 0.01 0.99 FALSE
26 GTEx Cells Transformed fibroblasts RP11-797A18.4 0.12 0.11 lasso 8 0.12 4.0e-09 7.7 -8.2 2.6e-16 -0.86 0.02 0.98 FALSE
27 GTEx Cells Transformed fibroblasts RP11-797A18.6 0.07 0.06 lasso 4 0.06 2.2e-05 8.2 -7.1 1.6e-12 -0.77 0.01 0.98 FALSE
28 GTEx Colon Transverse RP11-797A18.4 0.15 0.03 lasso 5 0.05 3.1e-03 -4.5 -6.9 4.7e-12 -0.77 0.04 0.89 FALSE
29 GTEx Esophagus Gastroesophageal Junction RP11-797A18.4 0.14 0.11 enet 10 0.15 6.0e-06 4.9 -7.2 8.7e-13 -0.81 0.02 0.97 FALSE
30 GTEx Esophagus Mucosa RP11-797A18.4 0.14 0.05 enet 13 0.08 7.5e-06 -4.5 -5.2 2.3e-07 -0.67 0.09 0.90 FALSE
31 GTEx Esophagus Muscularis RP11-797A18.4 0.07 0.09 lasso 3 0.09 6.3e-06 8.2 -8.2 3.3e-16 -0.87 0.02 0.98 FALSE
32 GTEx Heart Atrial Appendage RP11-797A18.4 0.16 0.06 enet 17 0.11 1.5e-05 7.6 -6.4 1.3e-10 -0.72 0.14 0.82 FALSE
33 GTEx Heart Left Ventricle RP11-797A18.4 0.16 0.09 enet 12 0.08 3.3e-05 8.2 -7.7 1.1e-14 -0.84 0.02 0.98 FALSE
34 GTEx Lung RP11-797A18.3 0.05 0.03 enet 8 0.04 3.4e-04 -4.4 -6.8 1.1e-11 -0.79 0.08 0.80 FALSE
35 GTEx Lung RP11-797A18.4 0.19 0.09 enet 21 0.17 3.5e-13 7.6 -7.4 1.2e-13 -0.68 0.13 0.87 FALSE
36 GTEx Muscle Skeletal HMG20A 0.04 0.00 lasso 4 0.01 7.2e-02 6.1 -6.2 4.1e-10 -0.55 0.03 0.76 FALSE
37 GTEx Muscle Skeletal RP11-797A18.4 0.14 0.14 lasso 6 0.18 6.6e-17 7.7 -7.2 5.7e-13 -0.81 0.05 0.95 FALSE
38 GTEx Nerve Tibial TSPAN3 0.13 0.08 lasso 2 0.07 9.0e-06 8.2 -8.1 4.1e-16 -0.85 0.01 0.99 FALSE
39 GTEx Ovary RP11-797A18.6 0.21 0.04 enet 15 0.13 3.7e-04 8.2 -6.3 2.4e-10 -0.78 0.04 0.61 FALSE
40 GTEx Skin Not Sun Exposed Suprapubic RP11-797A18.3 0.15 0.08 lasso 3 0.09 1.2e-05 -4.4 -7.2 7.2e-13 -0.78 0.16 0.79 FALSE
41 GTEx Skin Not Sun Exposed Suprapubic RP11-797A18.4 0.19 0.10 enet 31 0.15 8.0e-09 7.9 -8.2 3.7e-16 -0.72 0.13 0.87 FALSE
42 GTEx Skin Sun Exposed Lower leg TSPAN3 0.11 0.03 enet 8 0.10 2.5e-08 -6.3 -7.0 2.5e-12 -0.68 0.08 0.84 FALSE
43 GTEx Skin Sun Exposed Lower leg RP11-797A18.4 0.16 0.08 enet 23 0.09 1.3e-07 7.7 -8.2 3.0e-16 -0.84 0.04 0.96 FALSE
44 GTEx Testis PSTPIP1 0.10 0.03 lasso 3 0.02 4.1e-02 7.9 -7.8 4.3e-15 -0.81 0.05 0.80 FALSE
45 GTEx Testis TSPAN3 0.19 0.05 lasso 7 0.06 1.6e-03 7.6 -6.6 3.3e-11 -0.72 0.05 0.84 FALSE
46 GTEx Testis RP11-797A18.6 0.09 -0.01 enet 14 0.01 1.7e-01 -4.0 -5.8 8.7e-09 -0.49 0.06 0.29 FALSE
47 GTEx Uterus RP11-797A18.4 0.26 0.11 enet 12 0.16 4.0e-04 8.4 -6.5 9.7e-11 -0.84 0.01 0.90 FALSE
48 GTEx Whole Blood TSPAN3 0.05 0.04 lasso 2 0.03 1.8e-03 -6.3 -6.7 2.5e-11 -0.55 0.11 0.35 FALSE
49 GTEx Whole Blood RP11-797A18.3 0.08 0.05 lasso 7 0.05 4.4e-05 -4.4 -5.1 2.9e-07 -0.66 0.30 0.66 FALSE
50 GTEx Whole Blood RP11-797A18.4 0.21 0.18 enet 26 0.19 1.6e-17 -4.4 -5.7 1.5e-08 -0.64 1.00 0.00 FALSE
51 GTEx Whole Blood RP11-797A18.6 0.04 0.02 enet 8 0.03 4.9e-04 -4.4 -6.0 2.2e-09 -0.75 0.14 0.40 FALSE
52 METSIM Adipose PSTPIP1 0.04 0.04 lasso 3 0.04 2.3e-06 -4.2 -5.3 9.5e-08 -0.54 0.59 0.39 FALSE
53 NTR Blood TSPAN3 0.07 0.08 lasso 9 0.09 5.1e-27 7.6 -7.2 7.5e-13 -0.79 0.43 0.57 FALSE
54 YFS Blood TSPAN3 0.18 0.14 bslmm 256 0.18 5.9e-57 -4.3 -5.7 1.3e-08 -0.53 1.00 0.00 FALSE
55 The Cancer Genome Atlas Bladder Urothelial Carcinoma TSPAN3 0.05 0.00 enet 7 0.02 9.7e-03 7.6 -7.5 9.2e-14 -0.71 0.01 0.73 FALSE
56 The Cancer Genome Atlas Breast Invasive Carcinoma SCAPER 0.05 0.02 lasso 3 0.02 7.5e-05 4.9 -5.2 1.8e-07 -0.36 0.01 0.99 FALSE
57 The Cancer Genome Atlas Breast Invasive Carcinoma TSPAN3 0.03 0.01 blup 43 0.01 8.2e-03 5.3 -7.2 6.7e-13 -0.68 0.03 0.64 FALSE
58 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SCAPER 0.11 0.01 lasso 3 0.01 2.2e-02 4.9 -5.3 1.4e-07 -0.41 0.02 0.68 FALSE
59 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TSPAN3 0.05 0.01 blup 43 0.01 1.5e-02 7.7 -7.8 7.2e-15 -0.78 0.01 0.47 FALSE
60 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SCAPER 0.06 0.00 enet 5 0.00 3.4e-01 5.2 -5.1 3.1e-07 -0.32 0.01 0.38 FALSE