Best TWAS P=1.1e-12 · Best GWAS P=8.85e-12 conditioned to 3.22e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | CCDC57 | 0.29 | 0.16 | enet | 26 | 0.13 | 3.0e-07 | 3.7 | 5.2 | 2.3e-07 | -0.02 | 0.44 | 0.34 | FALSE |
| 2 | GTEx | Artery Tibial | CCDC57 | 0.08 | 0.03 | enet | 7 | 0.05 | 5.8e-05 | -4.1 | 5.2 | 1.9e-07 | -0.02 | 0.05 | 0.91 | FALSE |
| 3 | GTEx | Brain Cerebellar Hemisphere | BAIAP2 | 0.36 | 0.01 | enet | 22 | 0.02 | 8.5e-02 | -4.1 | 7.1 | 1.1e-12 | 0.00 | 0.04 | 0.14 | TRUE |
| 4 | GTEx | Brain Cortex | WDR45B | 0.21 | -0.01 | enet | 27 | -0.01 | 4.8e-01 | -2.4 | 5.3 | 1.1e-07 | -0.04 | 0.03 | 0.28 | TRUE |
| 5 | GTEx | Cells Transformed fibroblasts | CBX8 | 0.21 | 0.10 | lasso | 3 | 0.08 | 1.4e-06 | 6.3 | -6.3 | 2.9e-10 | -0.58 | 0.01 | 0.99 | FALSE |
| 6 | GTEx | Lung | CBX8 | 0.28 | 0.19 | enet | 24 | 0.18 | 1.4e-13 | 6.6 | -6.5 | 8.3e-11 | -0.55 | 0.00 | 1.00 | TRUE |
| 7 | GTEx | Nerve Tibial | CBX8 | 0.16 | 0.14 | lasso | 4 | 0.14 | 5.3e-10 | 6.2 | -6.4 | 1.5e-10 | -0.59 | 0.01 | 0.99 | FALSE |