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chr11:64,501,991-66,919,278

Best TWAS P=1.02e-10 · Best GWAS P=9.99e-14 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Esophagus Muscularis	CTD-3074O7.5	0.22	0.02	enet	17	0.09	3.7e-06	-3.2	6.5	1.0e-10	-0.50	0.29	0.47	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	4.7	6.1	1.1e-09	-0.34	1.00	0.00	TRUE
12	GTEx	Thyroid	PACS1	0.09	0.04	enet	16	0.09	2.8e-07	-7.2	-5.8	6.3e-09	0.79	0.02	0.98	TRUE
4	GTEx	Breast Mammary Tissue (Male)	LTBP3	0.11	-0.01	enet	26	-0.01	5.8e-01	4.1	5.3	1.1e-07	-0.08	0.03	0.25	TRUE
9	GTEx	Heart Atrial Appendage	KLC2	0.10	0.04	lasso	8	0.09	1.1e-04	4.0	-5.3	1.3e-07	0.56	0.28	0.40	TRUE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNX32	0.15	0.17	blup	60	0.17	2.9e-34	5.6	5.3	1.4e-07	-0.16	0.00	1.00	TRUE
7	GTEx	Esophagus Muscularis	CNIH2	0.06	0.02	lasso	8	0.02	2.8e-02	4.0	5.2	2.6e-07	-0.53	0.09	0.56	TRUE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	SNX32	0.11	0.08	enet	5	0.07	9.7e-05	4.9	5.1	2.7e-07	-0.14	0.00	1.00	TRUE
10	GTEx	Heart Atrial Appendage	RP11-867G23.1	0.19	0.13	lasso	5	0.11	1.6e-05	-5.6	-5.7	1.3e-08	0.66	0.12	0.80	FALSE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SNX32	0.30	0.19	lasso	1	0.14	3.9e-06	5.6	5.6	1.9e-08	-0.12	0.00	1.00	FALSE
5	GTEx	Breast Mammary Tissue (Male)	NEAT1	0.27	0.01	enet	29	0.03	6.3e-02	3.9	5.6	2.1e-08	-0.16	0.04	0.26	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNX32	0.46	0.36	lasso	8	0.39	1.9e-50	5.6	5.6	2.6e-08	-0.16	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	FIBP	0.04	0.04	lasso	3	0.04	1.2e-05	5.6	5.5	3.1e-08	-0.13	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Stomach Adenocarcinoma	SNX32	0.12	0.13	blup	60	0.13	1.2e-09	4.7	5.5	3.3e-08	-0.16	0.04	0.96	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RP11-867G23.1	0.06	0.06	enet	7	0.02	1.3e-02	5.3	-5.4	5.9e-08	0.69	0.27	0.46	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	SNX32	0.23	0.26	lasso	7	0.25	6.4e-24	5.6	5.4	7.4e-08	-0.14	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	SNX32	0.14	0.09	blup	60	0.13	8.8e-15	5.6	5.4	7.9e-08	-0.16	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CNIH2	0.03	0.00	enet	4	0.02	6.4e-03	-4.8	5.3	1.2e-07	-0.58	0.06	0.13	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	SNX32	0.50	0.53	lasso	13	0.54	1.1e-81	5.6	5.3	1.4e-07	-0.13	1.00	0.00	FALSE
3	GTEx	Adrenal Gland	CTSW	0.13	0.08	lasso	12	0.06	3.0e-03	4.3	-5.2	1.9e-07	0.22	0.31	0.18	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	FIBP	0.40	0.21	enet	26	0.29	4.3e-10	4.7	5.1	2.7e-07	-0.17	0.99	0.00	FALSE