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Traits
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Traits
:
Leg fat-free mass (right)
:
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chr1:109,316,076-110,733,794
Best TWAS P=4.46e-09 · Best GWAS P=6.98e-07 conditioned to 0.386
109.4M
109.6M
109.8M
110M
110.2M
110.4M
110.6M
110.8M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Liver
ATXN7L2
0.39
0.04
lasso
12
0.21
1.3e-06
4.9
5.9
4.5e-09
0.75
0.04
0.87
TRUE
1
GTEx
Liver
SYPL2
0.34
0.27
lasso
5
0.30
4.6e-09
4.6
5.5
4.8e-08
0.88
0.04
0.95
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
SYPL2
0.07
0.04
blup
45
0.03
4.9e-04
4.6
-5.3
1.5e-07
-0.89
0.02
0.95
FALSE
3
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
MYBPHL
0.09
0.07
blup
46
0.06
5.7e-04
2.6
5.2
1.6e-07
0.81
0.01
0.68
FALSE
4
The Cancer Genome Atlas
Stomach Adenocarcinoma
SORT1
0.04
0.01
blup
60
0.03
4.4e-03
3.8
5.1
2.8e-07
0.75
0.02
0.26
FALSE