[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr7:75,913,086-78,122,616

Best TWAS P=1.76e-15 · Best GWAS P=2.32e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DTX2P1-UPK3BP1-PMS2P11	0.18	0.09	enet	21	0.12	6.1e-15	6.48	8.0	1.8e-15	0.82	0.00	1.00	TRUE
2	GTEx	Adipose Subcutaneous	RP11-467H10.2	0.12	0.00	lasso	6	0.01	2.1e-02	2.81	5.3	1.3e-07	0.05	0.13	0.04	FALSE
3	GTEx	Adipose Visceral Omentum	TMEM60	0.20	0.13	lasso	8	0.11	2.3e-06	-5.45	-5.5	2.9e-08	-0.01	0.06	0.94	FALSE
4	GTEx	Artery Aorta	GSAP	0.19	0.07	lasso	2	0.04	2.8e-03	4.83	-5.4	8.5e-08	-0.03	0.26	0.03	TRUE
5	GTEx	Artery Tibial	TMEM60	0.07	0.05	enet	12	0.02	6.6e-03	-5.29	-5.5	4.0e-08	0.00	0.03	0.94	FALSE
6	GTEx	Brain Frontal Cortex BA9	GSAP	0.38	0.22	lasso	6	0.21	3.0e-06	4.95	-6.0	1.6e-09	-0.13	0.14	0.20	TRUE
7	GTEx	Cells Transformed fibroblasts	TMEM60	0.25	0.20	lasso	4	0.20	1.5e-14	-5.29	-5.2	1.6e-07	-0.02	0.03	0.97	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	RSBN1L-AS1	0.38	0.41	lasso	12	0.44	1.2e-17	-5.45	-5.2	2.6e-07	-0.03	0.06	0.94	FALSE
9	GTEx	Esophagus Mucosa	TMEM60	0.06	0.04	lasso	2	0.04	1.0e-03	-5.29	-5.2	2.2e-07	-0.02	0.03	0.96	FALSE
10	GTEx	Muscle Skeletal	TMEM60	0.11	0.12	lasso	4	0.12	4.6e-12	-5.29	5.5	4.5e-08	0.02	0.02	0.98	FALSE
11	GTEx	Nerve Tibial	TMEM60	0.14	0.14	lasso	8	0.12	1.1e-08	-5.29	-5.3	1.3e-07	-0.02	0.05	0.95	FALSE
12	GTEx	Ovary	TMEM60	0.23	0.19	enet	7	0.13	5.2e-04	-5.04	-5.2	1.9e-07	0.01	0.07	0.66	FALSE
13	GTEx	Skin Sun Exposed Lower leg	TMEM60	0.10	0.10	lasso	3	0.09	1.4e-07	-5.29	-5.3	1.2e-07	-0.01	0.02	0.98	FALSE
14	GTEx	Skin Sun Exposed Lower leg	DTX2P1	0.16	0.03	enet	22	0.05	4.8e-05	7.01	5.3	1.3e-07	0.70	0.00	0.99	FALSE
15	GTEx	Testis	RSBN1L-AS1	0.16	0.12	lasso	8	0.16	1.5e-07	-4.89	-5.3	1.1e-07	0.00	0.10	0.89	FALSE
16	GTEx	Thyroid	AC007000.12	0.13	0.08	enet	24	0.07	2.6e-06	-4.82	-5.6	2.6e-08	-0.18	0.66	0.02	FALSE
17	GTEx	Whole Blood	TMEM60	0.05	0.04	enet	7	0.03	5.4e-04	-5.12	-5.4	5.8e-08	-0.02	0.04	0.96	FALSE
18	METSIM	Adipose	TMEM60	0.10	0.07	enet	9	0.08	2.1e-12	5.32	-5.3	1.1e-07	-0.02	0.02	0.98	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	RSBN1L	0.09	0.07	enet	42	0.08	9.9e-11	-4.31	-6.0	2.1e-09	-0.03	0.08	0.91	TRUE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	TMEM60	0.02	0.02	lasso	1	0.02	2.3e-05	5.65	-5.7	1.6e-08	0.00	0.00	1.00	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PMS2L11	0.05	0.02	enet	3	0.06	2.5e-07	-0.31	5.2	1.6e-07	0.71	0.01	0.97	TRUE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	RSBN1L	0.02	0.02	blup	58	0.02	3.4e-03	-5.29	5.5	3.7e-08	0.01	0.02	0.82	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM60	0.02	0.03	blup	29	0.02	6.8e-03	5.65	-5.5	3.6e-08	-0.01	0.00	0.92	FALSE
24	The Cancer Genome Atlas	Soft Tissue Sarcoma	PHTF2	0.06	0.04	blup	72	0.04	2.0e-03	5.07	-5.2	1.9e-07	-0.01	0.04	0.72	FALSE