TWAS hub - PMS2L11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0461	0.0213	6.5e-13	0.069	0.066	0.068	NA	0.067	5.3e-14	1.8e-13	8.4e-14	NA	1.3e-13
2	TCGA	Esophageal Carcinoma	0.1330	0.0730	7.7e-04	0.026	0.062	0.058	NA	0.038	5.1e-02	4.9e-03	6.4e-03	NA	2.3e-02
3	TCGA	Head and Neck Squamous Cell Carcinoma	0.0486	0.0251	6.1e-07	0.021	0.059	0.060	NA	0.055	1.7e-03	3.6e-07	2.5e-07	NA	8.6e-07
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0628	0.0307	1.2e-08	0.069	0.078	0.069	NA	0.076	3.0e-08	4.3e-09	3.2e-08	NA	6.6e-09
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0450	0.0300	4.6e-03	0.006	0.027	0.020	NA	0.022	1.4e-01	1.0e-02	2.3e-02	NA	1.9e-02
6	TCGA	Brain Lower Grade Glioma	0.0235	0.0141	7.8e-04	0.006	0.023	0.020	NA	0.015	5.8e-02	9.7e-04	2.1e-03	NA	7.2e-03
7	TCGA	Lung Adenocarcinoma	0.0487	0.0310	2.2e-05	0.043	0.041	0.042	NA	0.046	8.6e-06	1.4e-05	9.8e-06	NA	4.5e-06
8	TCGA	Prostate Adenocarcinoma	0.1123	0.0550	1.0e-08	0.085	0.089	0.085	NA	0.091	3.1e-09	1.5e-09	3.2e-09	NA	8.5e-10
9	TCGA	Soft Tissue Sarcoma	0.0750	0.0450	6.4e-04	0.074	0.048	0.048	NA	0.061	3.4e-05	8.1e-04	8.2e-04	NA	1.6e-04
10	TCGA	Thyroid Carcinoma	0.0950	0.0460	2.0e-08	0.093	0.087	0.088	NA	0.081	2.6e-09	7.4e-09	7.3e-09	NA	2.6e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Body Mass Index (BMI) (2010)	7.2	9.8	22.8	1.7	2.5	4.8	3.9	4.1	4.1	2.5	0.5	2.7	2.0
Ever had hysterectomy (womb removed)	5.1	5.7	8.8	-2.1	-2.3	-2.4	-3.0	-2.7	-2.9	-2.4	-1.7	-1.7	-2.4
BMI	4.7	27.5	57.8	2.5	3.6	7.2	7.1	7.6	7.5	4.2	1.1	2.0	4.1
Bilateral oophorectomy (both ovaries removed)	4.7	5.5	8.3	-1.9	-2.3	-2.9	-2.7	-2.7	-2.8	-2.4	-1.4	-1.5	-2.1
Exposure to tobacco smoke outside home	4.7	6.2	8.9	2.8	2.6	1.6	2.5	2.3	2.4	3.0	2.9	1.4	3.0
Comparative body size at age 10	4.6	12.6	23.4	2.1	2.9	4.8	4.6	4.8	4.8	3.1	1.1	2.1	2.8
Waist circumference	3.8	14.1	25.1	2.3	3.3	5.0	4.8	4.9	5.0	3.4	1.5	1.7	3.2
Number of children fathered	3.8	4.3	5.3	-2.3	-2.1	-2.0	-1.9	-1.9	-1.9	-2.3	-2.0	-2.1	-2.1
Medication: Gliclazide	3.8	4.3	6.3	2.2	2.5	1.7	2.1	1.7	1.9	2.2	2.2	1.4	2.4
Mother’s age at death	3.8	4.8	7.5	-2.6	-2.6	-1.5	-1.9	-1.5	-1.8	-2.5	-2.7	-1.7	-2.6
Body mass index (BMI)	3.1	13.0	29.1	1.3	2.3	5.1	5.0	5.4	5.3	2.8	0.3	1.0	2.6
Neck or shoulder pain in last month	3.1	4.3	6.1	-1.9	-2.0	-2.5	-2.3	-2.3	-2.3	-2.0	-1.4	-2.0	-1.9
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	5.0	2.2	1.9	1.3	1.5	1.3	1.4	1.9	2.1	2.1	1.9
Number of full brothers	3.0	3.8	5.2	-1.9	-1.7	-1.8	-2.3	-2.1	-2.2	-1.8	-1.8	-1.4	-2.2
Leg fat mass (right)	3.0	11.5	25.2	1.4	2.2	4.9	4.6	5.0	4.9	2.6	0.4	1.3	2.4
Leg fat mass (left)	3.0	11.8	24.5	1.5	2.4	4.8	4.7	4.9	4.9	2.7	0.6	1.2	2.6
Leg fat-free mass (left)	2.9	15.4	33.5	1.4	2.8	5.8	5.3	5.6	5.6	2.9	0.3	1.4	2.8
Arm fat mass (right)	2.9	11.8	24.6	1.5	2.4	4.9	4.7	5.0	4.9	2.7	0.5	1.2	2.6
Arm fat mass (left)	2.9	11.7	23.7	1.6	2.5	4.8	4.6	4.9	4.9	2.7	0.7	1.2	2.7
Leg predicted mass (left)	2.8	14.6	32.6	1.3	2.7	5.7	5.2	5.5	5.5	2.7	0.2	1.3	2.7
Suffer from ‘nerves’	2.8	4.4	7.0	-1.6	-2.1	-2.6	-2.6	-2.4	-2.6	-1.9	-1.2	-1.5	-1.9
Worry (Nagel 2018)	2.7	5.8	9.8	-2.0	-2.2	-3.1	-2.7	-2.8	-2.8	-2.3	-1.3	-2.4	-2.0
Diabetes (father)	2.7	3.3	10.5	1.5	0.7	2.5	1.6	2.1	1.8	1.3	0.6	3.2	0.8
Medication: Metformin	2.6	3.7	6.1	1.5	1.9	1.9	2.5	2.3	2.4	1.9	1.4	0.8	2.0
Falls in the last year	2.6	3.6	5.3	2.0	2.0	1.3	2.1	1.8	1.9	2.1	2.1	0.9	2.3
Nervous feelings	2.5	4.8	10.0	-1.7	-1.4	-3.2	-2.3	-2.7	-2.5	-1.8	-0.8	-2.8	-1.4
Weight	2.5	12.5	25.9	1.4	2.6	5.0	4.9	5.1	5.1	2.7	0.5	1.1	2.7
Impedance of leg (left)	2.4	11.6	28.0	-0.6	-1.8	-5.2	-4.7	-5.3	-5.1	-2.3	0.5	-0.5	-2.0
Had menopause	2.4	3.0	4.6	-1.8	-1.9	-1.0	-2.1	-1.5	-1.8	-1.8	-1.9	-1.0	-2.1
Medication: Ramipril	2.4	3.1	5.3	1.3	1.7	1.8	2.3	2.1	2.3	1.8	1.1	0.5	1.8
Had major operations	2.4	2.8	4.5	1.4	1.6	2.1	1.8	1.8	1.9	1.5	1.0	1.8	1.4
Leg fat-free mass (right)	2.4	12.9	28.2	1.3	2.8	5.3	4.9	5.1	5.2	2.6	0.3	1.1	2.6
Basal metabolic rate	2.4	13.3	28.9	1.2	2.6	5.4	5.0	5.3	5.3	2.6	0.2	1.0	2.6
Medication for hormone replacement therapy	2.3	2.6	3.6	-1.6	-1.9	-1.2	-1.7	-1.5	-1.6	-1.8	-1.7	-0.7	-1.9
Impedance of leg (right)	2.3	11.1	24.9	-0.8	-2.2	-4.9	-4.6	-5.0	-4.9	-2.4	0.2	-0.4	-2.2
Whole body fat mass	2.3	9.5	19.4	1.4	2.2	4.3	4.2	4.4	4.4	2.4	0.5	1.1	2.4
Ever had bowel cancer screening	2.3	2.7	4.8	-1.2	-1.7	-1.5	-2.2	-1.9	-2.1	-1.6	-1.2	-0.2	-1.9
Leg predicted mass (right)	2.3	12.4	27.5	1.2	2.7	5.2	4.8	5.0	5.1	2.5	0.2	1.0	2.5
Whole body water mass	2.2	12.5	28.5	1.0	2.5	5.3	4.8	5.1	5.1	2.4	0.0	1.0	2.4
Relative age voice broke	2.1	3.2	5.7	1.6	2.1	2.4	1.7	1.7	1.9	2.0	1.1	1.7	1.4
Arm fat percentage (right)	2.1	8.1	16.6	1.4	2.0	3.9	3.8	4.1	4.0	2.4	0.6	1.2	2.2
Medication: Seretide 50 evohaler	2.1	2.4	5.3	1.9	1.3	1.4	1.3	1.3	1.3	1.5	1.5	2.3	1.4
Illnesses of father: Heart disease	2.1	2.9	4.5	1.6	1.4	2.1	1.7	2.0	1.9	1.9	1.2	1.5	1.5
Whole body fat-free mass	2.1	11.9	26.9	0.9	2.4	5.2	4.8	5.0	5.0	2.3	-0.1	0.7	2.4
Diabetes diagnosed by doctor	2.1	3.5	6.1	1.5	1.4	2.1	2.3	2.5	2.4	1.9	1.2	1.2	1.8
Impedance of whole body	2.1	10.8	26.3	-0.5	-1.7	-5.1	-4.5	-5.1	-4.9	-2.1	0.7	-0.3	-1.9
Arm predicted mass (left)	2.1	10.7	25.6	0.8	2.2	5.1	4.5	4.8	4.8	2.2	-0.2	0.8	2.1
Medication: Co-codamol	2.0	2.3	4.1	-1.1	-1.4	-1.7	-2.0	-1.8	-1.9	-1.3	-0.8	-1.0	-1.4
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	3.5	-1.4	-1.8	-1.4	-1.9	-1.5	-1.7	-1.5	-1.4	-1.0	-1.7
Trunk fat mass	2.0	8.8	17.1	1.5	2.4	4.1	3.9	4.1	4.1	2.5	0.7	1.2	2.4
Medication: Paracetamol	2.0	3.3	5.8	-1.5	-1.9	-2.4	-2.0	-1.9	-2.1	-1.7	-1.1	-1.7	-1.6
Leg fat percentage (right)	2.0	7.1	14.5	1.5	1.8	3.6	3.5	3.8	3.7	2.3	0.8	1.3	2.1
Arm fat percentage (left)	2.0	8.0	16.6	1.4	2.0	3.8	3.8	4.1	4.0	2.4	0.6	1.0	2.2
Leg fat percentage (left)	2.0	7.4	13.7	1.7	2.2	3.6	3.5	3.7	3.7	2.5	1.0	1.2	2.3
Arm fat-free mass (left)	2.0	10.2	24.9	0.7	2.1	5.0	4.4	4.7	4.7	2.0	-0.3	0.6	2.0
Ever used hormone-replacement therapy (HRT)	1.9	2.5	4.4	-1.3	-1.6	-1.0	-2.1	-1.7	-1.9	-1.6	-1.4	-0.0	-2.0
Tense / ‘highly strung’	1.9	3.1	6.9	-1.0	-1.4	-2.6	-2.2	-2.3	-2.3	-1.3	-0.4	-1.7	-1.2
Hearing difficulty/problems: Yes	1.8	2.7	4.1	-1.6	-1.4	-1.4	-2.0	-1.8	-1.9	-1.5	-1.5	-1.0	-1.9
Arm predicted mass (right)	1.8	9.1	22.3	0.5	2.0	4.7	4.2	4.5	4.5	1.9	-0.4	0.4	1.9
Type 2 Diabetes (T2D) (2018)	1.7	3.2	5.2	1.5	1.5	1.8	2.3	2.2	2.2	1.7	1.4	0.9	2.0
Hand grip strength (left)	1.7	4.5	6.8	2.4	2.6	1.7	2.1	1.5	1.9	2.1	2.3	2.2	2.3
Impedance of arm (left)	1.7	7.9	20.6	-0.4	-1.6	-4.5	-3.7	-4.3	-4.1	-1.8	0.6	-0.5	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.7	2.6	4.4	-1.4	-1.5	-2.1	-1.8	-1.9	-1.9	-1.6	-0.9	-1.5	-1.4
Mouth/teeth dental problems: Loose teeth	1.7	2.0	3.0	-1.3	-1.5	-1.7	-1.5	-1.6	-1.6	-1.5	-0.9	-1.1	-1.3
Medication: Allopurinol	1.7	2.3	4.5	0.8	1.4	2.0	2.1	2.0	2.1	1.3	0.4	0.5	1.3
Tinnitus: Yes, now most or all of the time	1.7	2.0	4.6	-0.5	-0.9	-1.6	-2.0	-2.1	-2.1	-1.1	-0.4	0.4	-1.3
Smoking Status	1.6	3.9	5.1	1.9	1.7	2.0	2.2	2.2	2.2	2.1	1.5	1.8	1.8
Average weekly fortified wine intake	1.6	1.9	3.1	-1.2	-1.8	-1.5	-1.5	-1.4	-1.6	-1.6	-1.0	-0.4	-1.4
Trunk fat-free mass	1.6	9.4	21.4	0.7	2.0	4.6	4.3	4.5	4.5	1.9	-0.2	0.5	2.1
Hip circumference	1.6	7.0	15.8	0.6	1.7	3.7	3.8	4.0	4.0	1.7	0.0	0.1	2.0
Number of live births	1.6	2.2	4.8	-1.0	-1.4	-1.3	-2.2	-1.8	-2.0	-1.2	-1.0	-0.5	-1.7
Trunk predicted mass	1.6	9.3	21.1	0.6	2.0	4.6	4.3	4.5	4.5	1.9	-0.2	0.4	2.0
Loud music exposure frequency	1.6	1.8	4.2	-0.8	-0.7	-1.6	-1.8	-2.0	-1.9	-1.2	-0.4	-0.5	-1.1
Arm fat-free mass (right)	1.6	8.3	20.9	0.3	1.7	4.6	4.0	4.3	4.3	1.6	-0.6	0.3	1.7
Family relationship satisfaction	1.6	1.9	4.2	1.5	2.1	0.7	1.3	0.7	1.1	1.6	1.7	0.6	1.7
Medication: Paracetamol	1.6	2.5	4.7	-1.3	-1.5	-2.2	-1.7	-1.8	-1.8	-1.5	-0.8	-1.6	-1.2
Chronotype (morning person)	1.5	3.6	7.3	1.2	1.4	1.9	2.7	2.6	2.6	1.6	1.1	0.5	2.0
Multivitamins +/- minerals	1.5	2.0	3.0	1.2	1.5	1.7	1.5	1.5	1.6	1.5	0.9	1.1	1.2
Osteoporosis (self-reported)	1.5	1.8	2.6	-1.4	-1.0	-1.3	-1.5	-1.6	-1.5	-1.5	-1.2	-1.1	-1.4
Medication: Bendroflumethiazide	1.5	2.3	5.1	-2.0	-2.1	-0.3	-1.0	-0.5	-0.8	-1.8	-2.3	-1.0	-1.9
Heart disease (siblings)	1.5	1.9	3.9	-0.8	-1.3	-1.6	-2.0	-1.7	-1.9	-1.0	-0.5	-0.7	-1.2
Severe depression (siblings)	1.4	1.5	2.3	-1.2	-1.3	-0.8	-1.5	-1.2	-1.4	-1.4	-1.3	-0.4	-1.5
Father’s age at death	1.4	1.9	3.9	-0.9	-1.2	-2.0	-1.6	-1.7	-1.7	-1.2	-0.4	-1.2	-0.9
Commuting to job workplace: Cycle	1.4	1.7	2.6	1.5	1.2	1.0	1.3	1.2	1.2	1.3	1.5	1.0	1.6
Alcohol intake versus 10 years previously	1.3	1.9	3.2	1.3	0.8	1.4	1.6	1.8	1.6	1.5	0.9	1.3	1.1
Body fat percentage	1.3	5.3	10.4	1.2	1.8	3.1	3.0	3.2	3.2	2.0	0.7	0.9	1.9
Medication: Aspirin	1.3	1.6	3.0	1.1	1.4	0.5	1.6	1.2	1.4	1.4	1.4	-0.3	1.7
Ever had prostate specific antigen (PSA) test	1.3	1.5	4.0	-1.7	-1.3	-0.8	-0.6	-0.4	-0.5	-1.3	-1.6	-2.0	-1.1
Trunk fat percentage	1.2	4.7	8.6	1.3	1.8	2.9	2.8	2.9	2.9	1.9	0.7	1.0	1.8
Current tobacco smoking	1.2	1.9	3.0	1.7	1.3	0.9	1.2	1.2	1.2	1.7	1.7	1.2	1.6
Maternal smoking around birth	1.2	1.8	3.1	-1.2	-0.7	-1.2	-1.8	-1.7	-1.6	-1.0	-1.0	-1.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	7.0	0.7	0.9	1.9	2.6	2.4	2.5	0.9	0.4	0.9	1.4
Mouth/teeth dental problems	1.2	1.8	4.8	1.0	1.0	2.2	1.2	1.5	1.4	1.0	0.3	2.0	0.7
Impedance of arm (right)	1.2	5.4	13.4	0.1	-1.1	-3.6	-3.2	-3.7	-3.5	-1.3	0.8	0.4	-1.2
Prospective memory result	1.2	1.5	3.5	1.5	1.6	0.1	1.0	0.5	0.8	1.3	1.9	0.5	1.6
Pulse wave Arterial Stiffness index	1.2	1.4	4.1	1.3	0.8	1.5	0.8	1.1	0.9	1.1	0.8	2.0	0.8
Pulse wave reflection index	1.2	1.5	2.6	1.1	0.8	1.5	1.3	1.4	1.3	1.1	0.7	1.6	0.9
Medication for pain relief, constipation, heartburn	1.2	2.1	3.7	1.3	1.4	1.9	1.5	1.6	1.6	1.4	0.9	1.6	1.2
Medication: Ibuprofen	1.2	1.4	2.8	-1.0	-0.8	-1.2	-1.5	-1.7	-1.6	-1.4	-0.6	-0.5	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	4.3	-0.9	-0.7	-2.1	-1.6	-1.9	-1.8	-1.1	-0.2	-1.6	-0.7
Financial situation satisfaction	1.2	1.4	1.9	1.2	1.4	1.2	1.3	1.2	1.2	1.3	1.1	0.8	1.3
Heart attack/myocardial infarction (self-reported)	1.2	1.6	4.0	-0.5	-0.6	-2.0	-1.6	-1.8	-1.7	-0.6	0.0	-1.3	-0.7
Fasting Glucose	1.1	1.3	2.1	-1.0	-0.7	-1.4	-1.3	-1.4	-1.3	-1.0	-0.7	-1.4	-0.9
Stomach or abdominal pain in last month	1.1	1.4	3.0	-1.4	-1.7	-0.4	-1.0	-0.5	-0.8	-1.3	-1.6	-0.4	-1.6
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	2.5	-1.4	-1.0	-1.4	-1.3	-1.4	-1.3	-1.3	-1.1	-1.6	-1.3
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	3.3	-1.1	-1.4	-0.4	-1.6	-1.3	-1.4	-1.4	-1.5	0.5	-1.8
Long-standing illness, disability or infirmity	1.1	1.6	5.1	-1.6	-1.2	-1.2	-0.9	-0.8	-0.8	-1.2	-1.2	-2.2	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	4.1	0.5	0.6	2.0	1.0	1.4	1.2	0.7	-0.1	1.6	0.3
Ever taken oral contraceptive pill	1.1	1.2	2.5	-1.2	-1.6	-0.1	-1.0	-0.5	-0.8	-1.3	-1.5	0.1	-1.4
Relative age of first facial hair	1.0	2.1	5.2	1.1	1.6	2.3	1.4	1.4	1.5	1.3	0.5	1.7	0.9
Hair/balding pattern: Pattern 2	1.0	1.3	3.0	-0.4	-1.1	-1.0	-1.7	-1.5	-1.6	-0.8	-0.4	0.5	-1.2
Heart attack	1.0	1.3	3.3	-0.5	-0.7	-1.8	-1.5	-1.5	-1.5	-0.5	-0.1	-1.3	-0.7
Breastfed as a baby	1.0	1.2	2.0	1.3	0.6	1.2	0.8	1.3	1.1	1.4	0.8	1.4	0.7
Blood clot in the leg (DVT)	1.0	1.3	3.1	-0.5	-0.4	-1.7	-1.4	-1.8	-1.6	-0.8	0.0	-0.8	-0.6
Smoking status: Current	1.0	1.6	2.5	1.6	1.0	0.8	1.2	1.2	1.2	1.6	1.5	1.0	1.5
Verbal and Numeric Reasoning (VNR)	0.9	2.1	3.4	1.5	0.8	1.6	1.5	1.8	1.6	1.5	1.0	1.6	1.2
HDL Cholesterol	0.9	1.5	3.1	-1.6	-1.8	-0.7	-0.6	-0.2	-0.5	-1.3	-1.7	-1.5	-1.3
Neuroticism (2016)	0.9	1.2	2.5	-0.8	-1.2	-1.6	-1.3	-1.1	-1.3	-0.9	-0.5	-1.2	-0.9
Length of working week for main job	0.9	1.0	1.4	1.0	0.9	1.0	1.1	1.0	1.1	0.9	0.8	1.2	1.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.6	4.1	-0.5	-0.6	-1.5	-1.6	-2.0	-1.8	-1.2	-0.2	0.1	-0.9
Pulse wave peak to peak time	0.9	1.0	3.3	-1.1	-0.5	-1.3	-0.7	-1.0	-0.8	-0.9	-0.6	-1.8	-0.6
Shortness of breath walking on level ground	0.9	1.0	2.2	1.3	1.1	0.3	0.9	0.6	0.8	1.1	1.5	0.7	1.3
Alcohol drinker status: Never	0.9	1.0	1.4	-1.1	-1.1	-0.9	-1.0	-0.9	-1.0	-1.2	-1.1	-0.8	-1.1
Ever depressed for a whole week	0.9	1.1	2.1	-0.7	-1.4	-1.1	-1.4	-1.1	-1.3	-1.0	-0.7	-0.2	-1.1
Lung FVC	0.8	4.2	8.2	-1.7	-1.6	-2.9	-2.2	-2.5	-2.4	-2.0	-0.8	-2.2	-1.4
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	1.6	1.0	1.2	1.0	1.1	1.0	1.1	1.0	1.0	0.6	1.2
Supplements: Zinc	0.8	0.9	2.1	0.6	0.4	1.3	1.1	1.5	1.3	1.0	0.2	0.5	0.6
Age when periods started (menarche)	0.8	1.9	2.5	1.3	1.3	1.4	1.6	1.3	1.5	1.2	1.1	1.5	1.4
Diabetes (self-reported)	0.8	1.2	2.3	0.8	0.6	1.5	1.2	1.5	1.4	1.0	0.4	0.9	0.8
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.7	-1.3	-1.1	-0.8	-0.7	-0.7	-0.8	-1.3	-1.1	-1.1	-0.9
Hair/balding pattern: Pattern 3	0.8	1.2	3.8	0.3	0.8	-1.7	0.5	-0.5	-0.0	0.2	1.4	-1.9	1.4
Age at first live birth	0.8	1.4	3.2	0.9	0.3	1.6	1.3	1.8	1.5	1.1	0.4	1.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.2	1.2	1.6	-0.4	0.1	-0.6	-0.2	0.8	1.8	0.3	1.3
Depression (Nagel 2018)	0.7	1.0	1.3	-1.2	-0.6	-0.7	-1.0	-1.1	-1.0	-1.1	-1.0	-1.0	-1.0
Crohns Disease (2017)	0.7	1.5	2.9	0.9	0.7	1.4	1.6	1.7	1.6	1.1	0.6	0.8	1.0
Breast Cancer	0.7	1.6	5.4	0.8	0.2	2.0	1.1	1.5	1.3	0.7	-0.0	2.3	0.3
Ovarian Cancer	0.7	0.9	2.3	1.3	1.4	0.0	0.3	-0.1	0.1	1.0	1.5	0.8	1.1
Blood Eosinophil Count	0.7	5.2	8.4	-2.5	-2.7	-1.4	-2.5	-1.7	-2.1	-2.2	-2.7	-1.6	-2.9
Respiratory disease	0.7	1.5	3.3	1.2	0.7	1.0	1.5	1.3	1.3	0.8	1.0	1.8	1.1
Hand grip strength (right)	0.7	1.9	2.6	1.5	1.6	1.1	1.4	1.0	1.2	1.3	1.5	1.5	1.5
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.6	-0.7	-0.8	-1.0	-1.2	-1.3	-1.3	-1.1	-0.5	-0.1	-0.9
Medication: Lansoprazole	0.7	0.8	2.1	-1.3	-0.6	-0.2	-0.3	-0.3	-0.2	-0.9	-1.3	-1.4	-0.8
Hair/balding pattern: Pattern 4	0.7	1.7	3.2	1.6	1.7	1.4	0.6	0.8	0.9	1.8	1.3	1.2	1.1
Medication: Omeprazole	0.7	0.8	1.6	-0.9	-1.2	-0.1	-1.0	-0.5	-0.8	-0.9	-1.2	-0.0	-1.3
Commuting to job workplace: Public transport	0.7	0.8	1.4	-1.1	-1.1	-1.1	-0.5	-0.5	-0.6	-1.0	-0.9	-1.2	-0.8
Risk taking	0.7	1.1	2.3	1.4	1.0	0.6	0.5	0.6	0.5	1.2	1.5	1.1	1.2
Deep venous thrombosis (DVT) (self-reported)	0.7	0.8	2.3	-0.2	-0.2	-1.4	-1.2	-1.5	-1.3	-0.6	0.2	-0.4	-0.4
Intelligence (Savage-Jansen 2018)	0.6	1.8	3.2	1.2	0.7	1.3	1.6	1.8	1.6	1.3	1.0	1.1	1.3
Alzheimer’s Disease (including proxy)	0.6	0.8	1.8	1.1	0.8	0.2	0.9	0.7	0.8	0.9	1.3	0.6	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.1	-0.1	0.1	1.4	2.0	1.8	1.9	0.1	-0.4	0.2	0.7
Medication: Atenolol	0.6	0.7	1.5	-1.0	-1.1	-0.1	-0.8	-0.4	-0.6	-0.9	-1.2	-0.3	-1.1
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.4	-0.6	-1.2	-0.5	-1.1	-0.7	-0.9	-0.8	-0.9	0.3	-1.2
Pain all over the body in last month	0.6	0.6	1.7	-1.0	-1.0	-0.5	-0.3	-0.1	-0.3	-0.8	-0.9	-1.3	-0.6
Worry too long after embarrassment	0.6	1.1	2.0	1.4	1.4	0.5	0.5	0.3	0.4	1.2	1.4	1.2	1.1
Number of full sisters	0.6	0.8	1.6	1.0	1.3	0.4	0.9	0.5	0.7	1.0	1.1	0.3	1.1
Commuting to job workplace: Walk	0.6	0.7	1.3	-0.5	-1.1	-0.6	-1.0	-0.8	-1.0	-0.9	-0.5	0.5	-0.9
Eye problems/disorders: Cataract	0.6	0.7	1.8	-0.8	-1.0	0.6	-0.6	-0.0	-0.3	-0.8	-1.3	0.6	-1.2
Myopia	0.6	0.9	2.6	1.2	1.6	0.1	0.5	-0.1	0.3	1.0	1.4	0.8	1.0
Irritable Bowel Disease (IBD)	0.5	1.1	2.7	0.3	0.2	1.6	1.5	1.7	1.5	0.4	-0.1	0.9	0.5
Allergy or Eczema	0.5	1.4	3.0	-0.4	-1.4	-0.7	-1.7	-1.2	-1.5	-0.9	-0.7	1.2	-1.5
Number of treatments/medications taken	0.5	0.9	1.7	-1.1	-1.3	-0.6	-0.8	-0.4	-0.6	-0.9	-1.2	-0.9	-1.1
Qualifications: CSEs or equivalent	0.5	0.6	1.3	-0.7	-1.2	-0.3	-0.7	-0.5	-0.7	-1.0	-0.9	0.6	-1.1
Financial difficulties in last 2 years	0.5	0.6	1.9	-1.1	-1.1	0.6	0.3	0.7	0.4	-0.7	-1.4	-0.5	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	1.7	-0.6	-0.4	-1.3	-0.9	-1.2	-1.0	-0.7	-0.3	-0.8	-0.6
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.2	-1.0	-1.5	-0.4	-0.7	-0.6	-0.8	-1.4	-1.2	0.5	-1.3
Peak expiratory flow (PEF)	0.5	1.2	3.6	1.4	1.7	-0.1	0.5	-0.3	0.2	0.9	1.9	0.9	1.4
Gout (self-reported)	0.5	0.7	1.0	0.6	1.0	0.9	1.0	0.9	1.0	0.8	0.6	0.2	0.9
Qualifications: College or University degree	0.5	1.5	2.6	1.0	0.8	1.6	1.4	1.5	1.4	1.0	0.6	1.5	0.9
Medication: Blood pressure	0.5	0.8	2.5	0.3	0.1	1.4	1.1	1.6	1.3	0.8	-0.2	0.3	0.4
Average weekly red wine intake	0.5	0.7	1.3	0.8	0.9	0.5	1.0	0.7	0.8	0.8	1.0	0.2	1.2
Breast cancer (self-reported)	0.5	0.6	1.2	-0.9	-0.7	0.1	-0.7	-0.6	-0.6	-1.0	-1.1	0.2	-1.1
Average weekly champagne plus white wine intake	0.5	0.7	1.7	-1.2	-0.6	-0.7	-0.4	-0.6	-0.5	-1.0	-1.0	-1.3	-0.7
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.2	-0.8	-1.0	-0.5	-1.0	-0.6	-0.8	-0.7	-1.0	-0.6	-1.1
Illnesses of father: High blood pressure	0.5	0.6	2.0	-0.7	-1.4	-0.6	-0.6	-0.2	-0.5	-0.7	-0.9	-0.4	-0.9
Cholesterol lowering medication	0.5	0.7	2.2	0.2	0.3	-1.1	-1.1	-1.5	-1.3	-0.2	0.7	-0.1	-0.1
Basal cell carcinoma (self-reported)	0.5	0.6	1.3	-1.1	-0.8	-0.6	-0.5	-0.5	-0.5	-0.9	-0.9	-1.1	-0.7
Ulcerative Colitis (UC)	0.4	0.7	1.9	-0.4	-0.6	1.4	0.8	1.1	0.9	-0.4	-1.0	0.9	-0.3
Age at First Birth	0.4	0.6	0.8	-0.8	-0.7	-0.8	-0.9	-0.9	-0.9	-0.8	-0.7	-0.7	-0.8
Neuroticism	0.4	1.0	1.8	-0.6	-0.8	-1.0	-1.4	-1.3	-1.4	-0.9	-0.5	-0.1	-1.0
Taking other prescription medications	0.4	0.6	1.8	-0.9	-0.7	-0.9	-0.7	-0.6	-0.6	-0.6	-0.7	-1.3	-0.6
Alcohol usually taken with meals	0.4	0.6	0.9	0.8	0.6	0.6	0.9	0.9	0.9	0.9	0.8	0.1	0.9
Mouth/teeth dental problems: Dentures	0.4	0.6	2.8	-0.9	-0.5	-1.0	-0.3	-0.5	-0.4	-0.6	-0.6	-1.7	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.4	0.0	-0.5	0.8	0.9	1.2	0.9	0.1	-0.3	0.4	0.2
Medication: Amlodipine	0.4	0.5	1.4	-0.6	-0.2	1.2	0.8	1.0	0.9	-0.2	-1.0	0.1	-0.3
High blood pressure (siblings)	0.4	0.6	2.0	-0.1	-0.7	1.1	0.8	1.4	1.1	0.2	-0.7	0.5	-0.1
Wheeze or whistling in the chest in last year	0.4	0.6	1.3	-0.9	-1.1	-0.8	-0.5	-0.3	-0.5	-0.8	-0.9	-1.0	-0.8
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	0.7	1.2	0.1	0.2	-0.2	0.1	0.6	1.0	0.2	0.8
Medication: Aspirin	0.4	0.6	1.1	0.4	0.6	-0.1	1.0	0.7	0.8	0.7	0.7	-1.0	1.1
Back pain experienced in last month	0.4	0.6	1.2	-1.0	-1.1	-0.6	-0.4	-0.2	-0.3	-0.7	-1.1	-0.9	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.2	-0.8	-1.5	-1.0	-1.0	-0.8	-1.0	-1.1	-0.7	-0.3	-1.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.7	-1.0	-0.5	0.4	0.0	0.3	0.2	-0.4	-1.3	-0.8	-0.8
Medication: Lisinopril	0.4	0.5	0.8	-0.8	-0.7	-0.7	-0.7	-0.6	-0.7	-0.8	-0.6	-0.9	-0.6
Ever smoked	0.4	0.7	1.4	1.1	0.9	0.6	0.6	0.7	0.7	1.2	1.0	0.6	0.9
Diastolic blood pressure, automated reading	0.4	1.1	3.6	0.5	0.7	1.9	1.0	1.4	1.3	0.9	-0.0	1.1	0.4
Neuroticism (Nagel 2018)	0.3	0.7	1.5	-0.4	-0.7	-1.2	-1.1	-1.1	-1.1	-0.6	-0.1	-0.6	-0.6
Alzheimer’s Disease (in mother)	0.3	0.3	0.9	0.5	0.5	-0.2	0.8	0.4	0.5	0.3	0.9	-0.0	1.0
Blood White Count	0.3	2.0	3.5	1.7	1.2	1.2	1.3	1.5	1.4	1.9	1.4	1.1	1.4
Waist Hip Ratio (WHR)	0.3	1.1	2.9	1.5	1.4	0.5	-0.1	-0.1	-0.0	1.2	1.4	1.7	0.8
Angina	0.3	0.3	0.5	-0.7	-0.7	-0.4	-0.5	-0.4	-0.5	-0.7	-0.6	-0.6	-0.6
Vitamin and mineral supplements	0.3	0.4	0.5	-0.5	-0.6	-0.5	-0.7	-0.7	-0.7	-0.7	-0.5	0.1	-0.7
High blood pressure	0.3	0.9	2.7	-0.2	-0.2	1.6	1.0	1.5	1.2	0.3	-0.9	0.7	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	-0.5	0.2	-0.7	-0.5	-0.9	-0.6	-0.5	-0.0	-1.0	-0.1
Qualifications: None of the above	0.3	0.7	1.8	0.6	0.5	-1.4	-0.7	-0.9	-0.8	0.5	1.2	-0.7	0.5
Allergy	0.3	0.7	2.6	-1.2	-0.5	-0.1	-0.2	-0.2	-0.1	-0.8	-1.1	-1.6	-0.6
Time employed in main current job	0.3	0.4	1.6	-0.7	-0.3	-0.3	0.6	0.3	0.4	-0.5	-0.4	-1.3	0.2
Pulse rate	0.3	0.5	0.6	0.7	0.5	0.6	0.7	0.7	0.7	0.8	0.5	0.7	0.6
Noisy workplace	0.3	0.3	1.2	0.5	0.2	-1.1	-0.1	-0.4	-0.3	0.3	1.0	-0.6	0.6
Depression (self-reported)	0.3	0.4	0.9	0.3	0.7	-0.5	0.5	-0.0	0.2	0.3	0.9	-1.0	1.0
Glaucoma (self-reported)	0.3	0.3	0.8	0.6	0.2	0.3	0.5	0.8	0.6	0.9	0.4	0.2	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.4	0.3	-0.2	0.8	0.1	0.4	0.2	-0.0	-0.1	1.5	-0.2
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.1	-0.3	0.5	-0.8	-0.2	-0.8	-0.5	-0.3	0.2	-1.1	0.1
Chest pain or discomfort	0.3	0.4	0.9	-0.2	-0.4	-0.9	-0.9	-0.8	-0.9	-0.2	-0.1	-0.4	-0.5
Hypertension (Self-reported)	0.3	0.9	2.8	0.0	-0.2	1.7	0.9	1.5	1.2	0.5	-0.7	0.8	-0.1
Mood swings	0.3	0.6	1.4	1.0	1.1	0.1	0.5	0.2	0.4	0.8	1.2	0.4	1.0
Friendships satisfaction	0.3	0.4	1.3	0.8	0.9	-0.3	0.1	-0.3	-0.0	0.6	1.1	0.3	0.8
Qualifications: nursing, teaching	0.3	0.5	1.3	0.8	1.1	-0.0	-0.3	-0.6	-0.4	0.5	1.1	0.5	0.6
Medication for cholesterol	0.3	0.5	1.0	0.4	0.7	0.0	0.9	0.7	0.8	0.7	0.7	-0.8	1.0
Wears glasses or contact lenses	0.3	0.4	1.2	0.3	-0.4	-0.3	-1.1	-0.7	-0.9	0.1	0.1	0.9	-0.6
Medication: Atorvastatin	0.3	0.4	1.0	-0.0	-0.2	-0.9	-1.0	-0.9	-1.0	-0.2	0.2	-0.2	-0.4
Irritability	0.3	0.5	1.6	0.8	0.9	-0.5	-0.4	-0.8	-0.6	0.3	1.3	0.5	0.6
Unable to work because of sickness or disability	0.3	0.3	1.1	0.5	1.1	-0.2	0.2	-0.1	0.2	0.7	0.8	-0.5	0.7
Pain experienced in last month	0.3	0.4	1.3	0.7	1.1	0.2	-0.1	-0.6	-0.3	0.3	0.8	1.2	0.4
Alzheimer’s Disease (in father)	0.2	0.2	1.1	0.4	0.2	0.5	-0.0	0.1	0.0	0.2	0.2	1.1	0.0
Blood Red Count	0.2	1.8	3.8	1.0	0.1	1.7	1.4	1.9	1.6	0.9	0.3	2.0	0.7
Cardiovascular Disease	0.2	0.6	2.0	0.1	0.0	1.4	0.8	1.3	1.1	0.5	-0.4	0.4	0.1
Lung FEV1/FVC ratio	0.2	0.9	1.7	1.2	1.3	0.7	0.2	0.3	0.3	1.3	1.2	0.8	0.9
Sensitivity / hurt feelings	0.2	0.4	1.3	-0.2	-0.1	-1.1	-0.7	-0.9	-0.8	-0.2	0.2	-0.9	-0.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.0	-0.4	0.3	-0.6	-0.4	-0.8	-0.5	-0.3	-0.1	-1.0	-0.1
Systolic blood pressure, automated reading	0.2	0.6	1.9	0.1	0.7	1.4	0.8	1.0	1.0	0.5	-0.0	0.0	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.9	0.4	1.0	-0.1	0.4	-0.1	0.2	0.4	0.6	-0.2	0.6
Serious illness, injury or assault to yourself	0.2	0.2	0.8	0.3	0.7	0.6	0.2	0.0	0.2	0.2	0.2	0.9	0.2
Sitting height	0.2	1.3	2.6	-1.2	-0.8	-1.3	-1.0	-1.4	-1.2	-1.6	-0.7	-0.9	-0.8
High blood pressure (mother)	0.2	0.3	1.2	-0.2	0.0	0.6	1.1	0.9	1.0	-0.0	-0.3	-0.2	0.3
Hearing difficulty/problems with background noise	0.2	0.3	0.7	-0.6	-0.5	0.2	-0.7	-0.4	-0.5	-0.5	-0.9	-0.0	-0.9
Had other major operations	0.2	0.3	0.8	-0.4	-0.5	0.5	-0.4	-0.0	-0.2	-0.4	-0.9	0.6	-0.8
Forced vital capacity (FVC)	0.2	0.6	1.5	0.6	1.0	-1.0	-0.3	-1.1	-0.7	0.1	1.2	0.0	0.7
Illnesses of siblings	0.2	0.2	0.7	0.4	0.8	-0.2	0.4	-0.1	0.2	0.3	0.8	-0.1	0.7
Worrier / anxious feelings	0.2	0.4	1.0	0.6	0.7	-0.7	-0.1	-0.4	-0.2	0.6	1.0	-0.6	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.6	0.7	1.2	-0.7	-0.1	-0.9	-0.5	0.2	1.3	0.2	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	0.6	0.6	0.0	-0.0	-0.1	-0.0	0.5	0.7	0.4	0.4
Medication: Cholesterol lowering	0.2	0.3	0.7	0.1	0.2	0.5	0.6	0.8	0.8	0.6	-0.0	-0.6	0.4
Exposure to tobacco smoke at home	0.2	0.2	0.7	0.1	-0.1	0.6	0.5	0.9	0.7	0.4	-0.1	-0.1	0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	-0.5	-0.5	-0.5	-0.5	-0.4	-0.5	-0.5	-0.4	-0.8	-0.4
Birth weight	0.2	0.5	0.8	0.8	0.8	0.4	0.7	0.6	0.6	0.7	0.8	0.4	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.8	-0.5	-0.7	-0.7	-0.5	-0.4	-0.5	-0.4	-0.4	-0.9	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.3	0.4	0.3	0.3	0.5	0.5	0.5	0.4	0.4	0.3	0.5
Migraine (self-reported)	0.2	0.2	0.5	0.2	-0.1	-0.5	-0.7	-0.6	-0.7	-0.0	0.3	0.3	-0.2
Mean time to correctly identify matches	0.2	0.4	1.4	0.1	-0.5	-1.2	-0.8	-0.7	-0.8	-0.0	0.4	-0.5	-0.1
Heart disease (mother)	0.2	0.3	0.8	0.6	0.9	-0.1	0.0	-0.1	0.1	0.8	0.8	-0.5	0.6
Age at last live birth	0.2	0.3	0.8	0.5	0.0	0.7	0.6	0.9	0.7	0.6	0.2	0.6	0.4
Knee pain experienced in last month	0.2	0.4	1.0	-0.6	-0.0	1.0	0.6	0.7	0.7	-0.2	-0.9	-0.4	-0.2
Mineral and other dietary supplements	0.2	0.2	0.8	0.4	0.9	0.0	0.4	-0.1	0.2	0.2	0.7	0.2	0.7
Osteoarthritis (self-reported)	0.2	0.2	0.6	-0.6	-0.6	0.1	-0.2	0.2	0.0	-0.1	-0.8	-0.7	-0.6
Illnesses of father: None of the above (group 1)	0.2	0.3	1.1	0.2	0.4	-1.0	-0.1	-0.8	-0.4	-0.1	0.7	-0.5	0.4
Miserableness	0.2	0.3	1.0	0.7	0.7	-0.5	0.2	-0.2	0.0	0.6	1.0	-0.1	0.7
Guilty feelings	0.2	0.3	0.7	-0.4	-0.6	0.5	-0.3	0.1	-0.1	-0.4	-0.8	0.8	-0.8
Medication: Blood pressure	0.2	0.3	1.1	-0.2	-0.1	1.1	0.4	0.6	0.5	-0.1	-0.7	0.9	-0.3
Age started oral contraceptive pill	0.2	0.2	1.0	0.2	-0.1	0.7	0.3	0.4	0.3	0.1	-0.1	1.0	-0.0
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.3	0.1	0.2	-1.1	-0.7	-1.1	-0.9	-0.2	0.6	-0.3	0.1
Alcohol drinker status: Previous	0.2	0.2	0.5	0.6	0.1	0.6	0.1	0.6	0.3	0.7	0.4	0.6	0.3
HbA1C	0.1	0.2	0.4	-0.1	0.6	0.4	0.4	0.3	0.4	0.3	-0.1	-0.6	0.2
Heel T-Score	0.1	1.0	2.6	-0.8	0.0	0.6	1.6	1.2	1.4	-0.4	-0.5	-1.4	0.7
Systolic Blood Pressure	0.1	0.3	0.5	-0.7	-0.2	-0.1	-0.6	-0.6	-0.6	-0.7	-0.6	-0.5	-0.5
Hypothyroidism (self reported)	0.1	0.2	0.4	-0.4	-0.6	0.3	0.4	0.4	0.3	-0.5	-0.6	0.4	-0.3
Average weekly spirits intake	0.1	0.1	0.5	-0.1	0.1	0.5	0.2	0.1	0.1	-0.2	-0.3	0.7	-0.2
Diabetes (mother)	0.1	0.1	0.2	0.1	0.3	0.3	0.3	0.4	0.4	0.3	0.0	-0.2	0.2
Pack years adult smoking proportion	0.1	0.2	1.1	0.2	1.0	-0.2	0.0	-0.5	-0.1	0.2	0.5	-0.5	0.4
Townsend deprivation index at recruitment	0.1	0.2	0.5	0.3	0.7	0.2	0.5	0.1	0.4	0.2	0.5	-0.1	0.6
Fed-up feelings	0.1	0.1	0.3	0.4	0.1	0.3	0.4	0.5	0.4	0.3	0.3	0.5	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	0.0	0.4	0.3	0.4	0.4	0.4	0.3	0.1	-0.5	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.7	0.4	-0.5	-0.1	-0.7	-0.3	-0.5	0.0	0.1	1.3	-0.4
Supplements: Glucosamine	0.1	0.1	0.7	-0.2	-0.1	-0.1	0.2	0.3	0.2	0.1	-0.1	-0.8	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.3	-0.2	-0.4	-0.2	0.5	0.5	0.4	-0.1	-0.1	-0.5	0.2
Number of incorrect matches in round	0.1	0.2	0.5	0.7	0.5	-0.0	0.2	0.1	0.1	0.6	0.7	0.6	0.4
Past tobacco smoking	0.1	0.3	0.6	-0.5	-0.5	-0.5	-0.5	-0.6	-0.6	-0.8	-0.3	0.0	-0.5
Medication: Simvastatin	0.1	0.1	0.5	-0.0	0.2	0.0	0.3	0.3	0.3	0.2	0.1	-0.7	0.3
Fluid intelligence score	0.1	0.1	0.7	0.1	-0.1	0.6	0.2	0.4	0.3	-0.0	-0.1	0.8	-0.0
Neuroticism score	0.1	0.3	0.6	0.5	0.4	-0.7	-0.6	-0.8	-0.7	0.3	0.7	-0.0	0.2
Happiness	0.1	0.1	0.3	-0.1	-0.0	0.1	-0.6	-0.5	-0.5	-0.2	-0.2	0.5	-0.5
Asthma	0.1	0.2	0.7	0.6	0.3	-0.2	0.2	-0.1	0.0	0.2	0.7	0.8	0.4
Lung cancer (father)	0.1	0.2	1.0	-0.4	0.4	-0.3	-0.0	-0.4	-0.1	-0.3	-0.1	-1.0	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.7	0.5	0.7	-0.2	0.3	-0.2	0.0	0.2	0.8	0.2	0.7
Birth weight of first child	0.1	0.2	1.4	0.2	0.3	0.7	-0.2	-0.1	-0.1	0.1	-0.2	1.2	-0.4
Headache pain in last month	0.1	0.2	0.4	0.4	-0.3	-0.7	-0.6	-0.3	-0.5	0.3	0.5	0.2	-0.0
Forced vital capacity (FVC), Best measure	0.1	0.2	0.6	0.3	0.5	-0.7	-0.0	-0.6	-0.3	-0.1	0.8	-0.0	0.5
Health satisfaction	0.1	0.2	0.6	-0.4	-0.8	0.0	-0.1	0.2	0.0	-0.4	-0.6	0.1	-0.5
Eye problems/disorders: None of the above	0.1	0.1	0.2	0.2	0.4	-0.3	0.3	-0.0	0.1	0.2	0.4	-0.4	0.4
Angina (self-reported)	0.1	0.1	0.2	-0.4	-0.5	-0.2	-0.3	-0.2	-0.3	-0.5	-0.3	-0.3	-0.3
Alcohol intake frequency.	0.1	0.2	0.3	-0.3	-0.4	-0.4	-0.5	-0.4	-0.5	-0.2	-0.2	-0.6	-0.4
Overall health rating	0.1	0.1	0.3	-0.3	-0.1	-0.3	-0.4	-0.4	-0.4	-0.2	-0.3	-0.6	-0.4
Leg pain on walking	0.1	0.2	0.8	-0.6	-0.2	-0.1	0.3	0.2	0.3	-0.2	-0.6	-0.9	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	-0.6	-0.3	0.0	0.1	0.0	0.1	-0.5	-0.5	-0.6	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.1	0.2	-0.4	-0.2	-0.0	0.2	0.2	0.1	-0.2	-0.3	-0.4	-0.1
Supplements: Vitamin C	0.1	0.1	0.3	-0.3	-0.4	0.3	0.4	0.6	0.4	-0.1	-0.4	-0.2	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	1.3	-0.3	0.4	-0.1	-0.1	-0.2	-0.1	0.1	-0.1	-1.1	0.0
Illnesses of siblings: Diabetes	0.1	0.1	0.7	0.2	0.8	0.2	-0.1	-0.3	-0.1	0.4	0.2	0.0	0.1
Smoking status: Previous	0.1	0.1	0.3	-0.1	0.1	0.4	0.3	0.5	0.5	0.3	-0.3	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.6	0.4	0.8	0.6	0.7	0.4	0.6	0.4	0.4	0.3	0.6
Loneliness, isolation	0.1	0.2	1.0	-0.5	-0.0	-0.1	0.2	0.1	0.2	-0.2	-0.4	-1.0	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.6	0.3	0.8	0.2	0.4	0.1	0.3	0.4	0.5	-0.1	0.5
Asthma (self-reported)	0.1	0.3	1.0	0.8	0.5	-0.1	0.3	-0.1	0.1	0.4	0.8	1.0	0.5
Hearing aid user	0.1	0.1	0.3	0.4	-0.2	0.1	-0.1	0.2	0.0	0.4	0.3	0.5	0.0
Eye problems/disorders: Glaucoma	0.1	0.1	0.4	0.6	0.1	-0.1	0.1	0.2	0.1	0.5	0.6	0.5	0.3
High cholesterol (Self-reported)	0.1	0.2	0.3	-0.3	-0.2	-0.5	-0.5	-0.5	-0.5	-0.2	-0.2	-0.5	-0.4
Number of operations (self-reported)	0.1	0.2	0.5	-0.4	-0.5	0.2	-0.5	-0.3	-0.4	-0.4	-0.7	0.5	-0.7
Average weekly beer plus cider intake	0.1	0.1	0.3	-0.1	0.0	-0.1	-0.4	-0.6	-0.4	-0.3	-0.3	0.5	-0.5
Fractured/broken bones in last 5 years	0.1	0.2	0.9	-0.1	0.7	0.1	0.4	0.2	0.4	0.3	0.1	-0.9	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.3	-0.2	-0.6	0.2	-0.5	-0.1	-0.3	-0.3	-0.4	0.5	-0.5
Supplements: Calcium	0.1	0.1	0.3	-0.2	-0.2	0.5	0.3	0.4	0.3	-0.2	-0.4	0.3	-0.1
Pack years of smoking	0.1	0.1	0.6	0.1	0.8	0.1	0.1	-0.2	0.1	0.2	0.2	-0.3	0.3
Bipolar Disorder (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder or Schizophrenia	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Depressed Affect (Nagel 2018)	0.0	0.0	0.0	0.0	-0.0	0.1	0.0	0.1	0.0	0.0	0.1	-0.0	0.1
Schizophrenia (2018)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.0	0.1	0.2	0.3	-0.2	-0.3	0.1	0.1	0.0	0.2	0.4	0.2	0.2
Prostate Cancer	0.0	0.0	0.2	-0.1	-0.5	0.0	-0.2	0.1	-0.0	-0.1	-0.3	0.0	-0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lupus	0.0	0.1	0.5	0.1	0.0	0.7	0.0	0.0	0.0	0.2	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Rheumatoid Arthritis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.3	0.6	0.8	0.8	0.2	0.3	0.2	0.3	0.8	0.8	0.5	0.5
Height	0.0	0.2	0.7	-0.1	0.8	0.3	0.5	0.0	0.3	0.0	0.3	-0.5	0.6
Hair Pigment	0.0	0.2	0.8	0.3	0.9	-0.3	-0.3	-0.6	-0.3	0.4	0.5	-0.2	0.2
Tanning	0.0	0.6	0.9	0.8	0.5	0.5	0.9	0.9	0.8	0.8	0.9	0.5	1.0
Illnesses of mother	0.0	0.0	0.2	-0.0	-0.4	0.2	0.0	0.2	0.1	-0.1	-0.2	0.4	-0.2
Standing height	0.0	0.2	0.9	0.3	1.0	0.5	0.4	-0.0	0.3	0.1	0.4	0.4	0.5
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.2	-0.0	-0.3	-0.4	0.3	0.2	0.2	-0.1	0.1	-0.4	0.2
Emphysema/chronic bronchitis	0.0	0.0	0.1	-0.1	0.2	-0.3	0.1	-0.2	-0.1	-0.2	0.2	-0.4	0.3
Pulse rate, automated reading	0.0	0.1	0.6	0.1	-0.2	-0.8	-0.4	-0.4	-0.4	0.0	0.3	-0.4	0.0
Comparative height size at age 10	0.0	0.1	0.4	0.1	0.3	0.2	0.6	0.4	0.5	0.0	0.2	-0.1	0.5
Handedness (chirality/laterality): Left-handed	0.0	0.1	0.2	0.0	0.1	-0.5	-0.1	-0.4	-0.3	-0.2	0.2	0.0	-0.0
Number of self-reported non-cancer illnesses	0.0	0.0	0.1	-0.1	-0.3	-0.2	-0.3	-0.0	-0.1	0.1	-0.2	-0.3	-0.3

Hub : Genes

PMS2L11

Models

Trait associations