Hub : Genes

RSBN1L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0860 0.0230 8.8e-09 0.093 0.087 0.093 0.088 0.092 2.0e-11 9.1e-11 2.0e-11 7.0e-11 2.4e-11
2 GTEx Brain Cerebellum 0.1400 0.0540 4.0e-03 0.125 NA 0.056 NA 0.128 1.6e-04 NA 9.3e-03 NA 1.3e-04
3 GTEx Colon Sigmoid 0.1660 0.0660 4.6e-03 0.085 NA 0.026 NA 0.054 6.1e-04 NA 4.1e-02 NA 5.5e-03
4 GTEx Esophagus Muscularis 0.0650 0.0310 9.7e-03 0.025 NA 0.002 NA 0.014 1.1e-02 NA 2.2e-01 NA 4.2e-02
5 NTR Blood 0.0277 0.0109 3.7e-03 -0.001 0.008 0.001 0.008 -0.001 7.9e-01 7.4e-04 1.0e-01 1.1e-03 8.6e-01
6 ROSMAP Brain Pre-frontal Cortex 0.0899 0.0278 1.7e-07 0.066 0.072 0.082 0.075 0.076 7.1e-09 1.3e-09 9.9e-11 6.5e-10 4.9e-10
7 YFS Blood 0.0274 0.0096 1.1e-06 0.018 0.016 0.018 0.016 0.014 8.2e-07 4.5e-06 1.1e-06 3.4e-06 1.8e-05
8 TCGA Brain Lower Grade Glioma 0.0180 0.0118 4.5e-03 0.021 0.018 0.014 NA 0.014 1.7e-03 3.4e-03 9.0e-03 NA 8.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.2 1.3 0.0 0.3 -0.3 -1.1 -0.2 0.3 0.1 0.1
Bipolar Disorder or Schizophrenia 0.1 0.3 0.6 0.4 -0.6 0.7 0.1 0.8 0.7 -0.4 -0.5
Depressed Affect (Nagel 2018) 0.2 0.4 1.3 -0.3 0.8 0.1 0.3 -1.1 0.5 0.7 0.6
Depression (Nagel 2018) 0.1 0.1 0.3 -0.1 0.2 0.1 -0.3 -0.2 0.5 0.5 0.0
Intelligence (Savage-Jansen 2018) 0.5 1.5 3.8 1.3 -1.5 0.9 0.3 0.4 1.5 -1.9 -1.2
Neuroticism (Nagel 2018) 0.6 1.5 4.2 1.1 -0.7 1.4 1.4 -0.7 2.0 -0.8 -1.0
Schizophrenia (2018) 0.4 0.8 1.3 0.4 -1.0 1.1 1.1 1.1 0.5 -0.7 -0.8
Schizophrenia vs Biploar Disorder 1.6 2.1 3.4 1.8 -1.3 1.9 0.9 0.2 1.0 -1.8 -1.9
Worry (Nagel 2018) 1.3 2.7 4.8 1.7 -1.4 1.9 2.2 0.5 2.1 -1.3 -1.6
Alzheimer’s Disease (in mother) 2.1 2.5 3.9 -1.2 1.8 -1.3 -1.5 -1.8 -1.4 2.0 1.4
Alzheimer’s Disease (in father) 0.4 0.4 1.3 0.1 1.1 -0.4 -0.8 0.6 0.8 0.4 0.2
Alzheimer’s Disease (including proxy) 1.9 2.8 6.4 -1.3 2.5 -1.7 -1.4 0.1 -0.9 2.3 1.7
Crohns Disease (2017) 0.6 1.2 2.4 -0.8 1.1 -0.8 -1.3 1.6 -0.5 1.4 1.0
Irritable Bowel Disease (IBD) 0.2 0.5 2.3 0.8 -0.0 0.8 0.2 1.5 0.8 -0.0 -0.2
Ulcerative Colitis (UC) 1.5 2.8 4.7 2.1 -1.1 2.2 1.7 0.7 2.1 -1.5 -1.4
Major Depression (MDD) 1.3 1.6 4.5 0.9 -1.1 1.2 1.3 2.1 0.4 -1.5 -1.0
Reaction Time 1.0 1.9 3.1 1.4 -1.1 1.6 1.5 1.4 1.1 -1.1 -1.8
Verbal and Numeric Reasoning (VNR) 1.4 3.3 7.0 1.9 -1.9 1.5 0.9 1.3 1.7 -2.6 -2.1
Breast Cancer 0.1 0.3 0.7 0.6 0.0 0.6 -0.4 -0.7 0.6 -0.9 -0.2
Ovarian Cancer 0.4 0.5 3.2 -0.0 0.1 0.2 -0.5 -1.8 -0.2 -0.6 0.2
Prostate Cancer 0.4 0.5 2.6 -0.4 -0.8 0.2 1.6 -0.4 -0.7 -0.6 0.1
Age at First Birth 1.2 1.7 3.8 1.4 -1.5 1.5 0.7 0.3 0.8 -2.0 -1.5
Bipolar Disorder (2011) 0.1 0.1 0.4 -0.3 0.1 0.1 0.2 -0.6 -0.1 -0.3 0.3
Body Mass Index (BMI) (2010) 2.8 3.8 8.5 -1.9 1.5 -2.1 -2.9 1.2 -2.6 1.0 1.6
Coronary Artery Disease (CAD) 1.2 1.4 3.5 1.1 -1.9 0.9 0.9 -0.7 0.9 -1.4 -1.3
Crohns Disease (2012) 1.5 2.5 3.0 -1.5 1.6 -1.6 -1.7 1.7 -1.7 1.1 1.6
Mean Putamen Volume 2.0 2.3 3.5 1.2 -1.7 1.2 1.3 1.9 1.6 -1.6 -1.4
Fasting Glucose 0.8 0.9 1.9 -1.3 0.7 -1.4 -0.9 0.2 -0.9 0.7 1.1
HbA1C 0.6 0.7 3.6 -0.5 0.1 -0.8 -1.9 -0.7 -0.9 0.1 0.1
HDL Cholesterol 1.2 2.0 3.6 -1.4 1.9 -1.4 -1.5 -1.1 -0.6 1.6 1.5
LDL Cholesterol 1.3 2.0 4.3 -1.8 1.4 -1.1 -0.1 0.9 -1.8 1.2 2.1
Lupus 1.3 2.0 3.4 1.3 -1.8 1.8 1.8 1.1 0.6 -1.2 -1.0
Neuroticism (2016) 0.1 0.2 0.6 0.4 0.3 0.8 0.4 -0.3 0.4 0.0 -0.2
Primary Biliary Cirrhosis 0.3 0.4 1.4 0.0 -0.0 0.2 -1.2 -1.1 0.0 -0.5 -0.2
Rheumatoid Arthritis 1.3 1.7 4.9 -1.0 1.7 -0.8 -1.0 0.4 -2.2 1.1 1.5
Schizophrenia (2014) 0.5 1.2 1.9 1.1 -1.4 1.3 1.0 0.2 0.9 -1.0 -1.2
Triglycerides 0.2 0.4 0.9 0.4 -0.6 0.8 0.9 -0.5 -0.7 -0.5 0.1
Type 2 Diabetes (T2D) (2012) 0.5 0.6 1.8 0.6 -0.5 0.2 0.9 0.5 0.4 -1.3 -0.8
Ulcerative Colitis 0.1 0.2 0.6 0.7 0.3 0.7 0.2 -0.2 0.8 -0.3 -0.0
Blood Eosinophil Count 4.0 31.1 47.5 6.3 -5.4 6.9 6.2 1.8 6.1 -4.7 -5.6
Blood Platelet Count 0.2 2.9 10.6 1.6 -0.8 1.6 1.7 3.2 0.5 -1.6 -1.1
Blood Red Count 0.3 3.0 6.2 -1.5 1.9 -1.9 -2.1 -0.6 -2.5 0.8 1.6
Blood White Count 0.2 1.8 9.4 0.8 0.1 1.2 1.7 3.1 0.0 -0.4 -0.2
Heel T-Score 0.1 0.7 2.8 0.3 0.9 -0.6 -0.7 -1.7 -0.2 0.8 -0.3
BMI 4.1 24.1 53.3 -5.1 5.1 -4.9 -3.9 0.6 -7.3 4.1 5.5
Height 1.1 21.7 36.2 -6.0 3.7 -5.6 -4.9 -1.0 -4.1 4.0 5.9
Waist Hip Ratio (WHR) 16.9 75.8 112.4 9.7 -9.7 9.0 6.9 3.0 9.1 -9.1 -10.6
Systolic Blood Pressure 2.3 11.5 23.8 4.4 -3.5 3.4 1.7 0.3 1.8 -4.2 -4.9
Smoking Status 0.1 0.2 0.8 -0.0 0.9 0.1 -0.0 0.7 0.1 0.5 0.2
Allergy or Eczema 1.4 3.6 6.3 1.5 -2.1 1.7 2.1 2.5 1.8 -1.6 -1.7
Cardiovascular Disease 1.7 5.5 12.0 2.7 -2.6 2.4 1.4 1.2 0.5 -3.5 -3.0
Hypothyroidism (self reported) 6.2 14.3 24.4 -4.3 4.2 -3.6 -3.0 -0.4 -4.0 3.9 4.9
Respiratory disease 1.8 4.0 9.9 -2.2 2.3 -1.6 -1.3 -0.3 -3.1 1.2 2.5
Type 2 Diabetes (T2D) (2018) 0.8 1.4 2.9 1.4 -1.7 1.2 1.2 0.3 0.4 -1.3 -1.4
Lung FEV1/FVC ratio 0.0 0.2 1.1 0.1 -0.2 -0.3 1.1 0.5 0.2 -0.4 -0.2
Lung FVC 0.1 0.3 0.8 -0.5 -0.9 -0.7 -0.3 -0.7 -0.5 0.1 -0.1
Neuroticism 0.3 0.8 3.1 0.5 -0.1 0.9 1.8 -0.1 1.4 -0.2 -0.3
Chronotype (morning person) 0.7 1.6 6.0 1.0 -1.5 0.7 -0.2 1.1 0.2 -2.5 -1.4
Hair Pigment 0.1 1.6 2.6 1.6 -1.0 1.1 0.7 1.3 1.3 -1.5 -1.2
Tanning 0.7 8.0 12.2 -2.4 3.5 -2.2 -3.4 -1.8 -3.5 2.4 2.9
Hand grip strength (left) 2.6 6.8 8.6 -2.6 2.9 -2.7 -2.9 -0.9 -2.5 2.9 2.9
Number of treatments/medications taken 0.1 0.2 1.1 0.3 -0.0 0.2 0.5 1.1 -0.1 -0.4 -0.1
Average weekly spirits intake 0.5 0.6 1.2 -0.7 0.6 -1.1 -0.9 -1.0 -0.2 1.0 0.5
Sensitivity / hurt feelings 0.2 0.4 1.4 -0.2 1.2 -0.1 -0.5 -1.1 0.3 0.4 0.4
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.4 0.1 -0.3 0.5 0.6 -0.5 0.6 0.2 -0.2
Hearing difficulty/problems: Yes 0.4 0.5 1.5 -0.8 0.7 -0.8 -1.2 0.0 -0.5 0.6 0.7
Relative age of first facial hair 0.8 1.7 4.0 1.4 -0.8 2.0 1.3 -0.5 1.8 -0.8 -1.0
Other serious medical condition/disability diagnosed by doctor 1.4 1.8 2.9 1.3 -1.7 1.3 1.3 -0.1 1.7 -1.7 -1.2
Ever used hormone-replacement therapy (HRT) 0.7 0.9 2.2 -1.3 0.6 -1.1 -0.4 -0.3 -0.1 1.1 1.5
Ever had hysterectomy (womb removed) 0.5 0.5 1.1 0.9 -0.9 1.0 0.7 -0.1 0.3 -0.5 -0.8
Systolic blood pressure, automated reading 0.1 0.3 1.1 0.5 -0.1 0.1 -0.1 1.0 -0.7 -0.6 -0.5
Eye problems/disorders: Diabetes related eye disease 2.3 2.5 3.5 1.7 -1.8 1.9 1.6 0.0 1.5 -1.7 -1.8
Angina 0.3 0.3 0.7 0.4 -0.9 0.8 -0.4 -0.2 0.5 -0.7 -0.5
Medication for hormone replacement therapy 1.5 1.7 4.2 -1.4 1.7 -0.9 0.1 -0.3 -0.6 1.7 2.0
Vitamin and mineral supplements 0.5 0.6 2.1 0.7 0.5 1.1 -0.5 1.5 0.8 0.0 -0.2
Supplements: Zinc 1.5 1.7 2.5 -1.4 0.9 -1.1 -1.5 -1.1 -1.0 1.6 1.5
Medication: Co-codamol 0.3 0.4 2.0 -0.3 0.3 -0.5 -0.1 -1.4 0.5 0.4 0.3
Medication: Metformin 0.8 1.1 1.5 1.0 -1.2 1.0 0.7 1.1 1.0 -1.1 -1.0
Diabetes (father) 0.2 0.3 0.6 0.5 0.7 0.5 -0.4 0.1 0.2 -0.7 -0.5
Diabetes (mother) 0.3 0.4 2.3 -0.3 0.3 -0.7 -0.5 -0.1 -1.5 -0.2 0.2
Severe depression (siblings) 0.8 0.8 1.6 0.8 -0.8 1.0 0.7 0.8 1.0 -1.3 -0.7
Pack years adult smoking proportion 0.6 0.9 2.0 0.8 -0.9 1.2 0.8 1.4 0.9 -1.0 -0.7
Impedance of leg (right) 0.5 2.4 6.3 1.0 -1.5 1.3 2.5 -1.2 2.0 -1.2 -1.2
Leg fat-free mass (left) 4.8 25.3 38.3 -5.2 5.3 -5.3 -5.3 0.1 -6.2 4.5 5.7
Trunk fat percentage 6.4 25.7 50.2 -5.6 5.3 -5.3 -3.2 0.3 -7.1 4.5 6.1
Hand grip strength (right) 3.0 8.2 11.4 -2.8 3.4 -2.6 -3.1 -1.8 -2.7 2.9 3.3
Townsend deprivation index at recruitment 0.7 1.0 1.8 -1.3 1.0 -0.7 -0.9 0.2 -1.3 1.2 1.1
Current tobacco smoking 0.2 0.3 0.8 0.4 0.0 0.6 0.0 0.6 0.9 -0.4 -0.4
Average weekly fortified wine intake 0.4 0.5 1.1 -0.4 1.0 -0.0 0.4 -1.0 0.4 0.9 0.6
Maternal smoking around birth 0.6 0.9 1.6 -0.9 1.3 -0.7 -0.3 1.0 0.0 1.3 1.1
Fed-up feelings 0.9 1.6 3.0 -1.4 1.7 -1.3 -0.5 -0.4 -0.7 1.6 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.2 0.9 -0.2 0.3 -0.1 -0.0 -1.0 0.1 0.6 -0.0
Relative age voice broke 0.5 0.8 2.9 0.4 -0.2 0.8 1.7 -0.7 1.2 0.9 0.0
Taking other prescription medications 0.3 0.5 1.5 0.5 -0.0 0.8 0.7 1.2 -0.2 -1.0 -0.4
Age when periods started (menarche) 0.2 0.6 1.8 -0.6 1.1 -0.0 -0.4 -1.3 -0.4 0.3 1.0
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.7 -0.2 0.8 -0.3 -0.8 -0.2 -0.2 0.7 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 2.0 1.2 -0.2 1.1 0.7 -0.4 1.4 -0.4 -1.1
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 2.7 -0.4 0.6 -0.3 -1.1 -1.6 -0.9 -0.6 0.4
Qualifications: CSEs or equivalent 2.4 3.2 5.6 -2.1 1.9 -1.9 -0.9 -0.2 -2.4 2.0 1.8
Serious illness, injury or assault to yourself 1.0 1.2 2.8 1.4 -0.9 1.3 -0.1 -0.4 0.8 -1.1 -1.7
High blood pressure 3.4 9.6 16.5 3.8 -3.5 3.2 1.7 -0.1 2.0 -3.9 -4.1
Hayfever, allergic rhinitis or eczema 2.2 4.8 7.5 2.0 -2.4 2.0 2.3 2.7 2.1 -1.8 -2.2
Multivitamins +/- minerals 0.6 0.7 4.4 -0.0 -0.7 -0.3 0.8 -2.1 0.1 -0.3 -0.3
Stomach or abdominal pain in last month 0.1 0.1 0.4 -0.1 0.0 0.1 0.4 -0.3 0.1 0.6 -0.1
Supplements: Glucosamine 0.9 1.2 4.0 0.8 -1.1 0.6 1.2 -2.0 0.8 -0.9 -0.8
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.1 0.5 0.0 0.9 1.0 0.2 0.8 0.3 -0.2
Medication: Atenolol 1.3 1.7 3.3 1.3 -1.2 1.5 1.3 -0.6 1.8 -0.9 -1.3
Medication: Levothyroxine sodium 1.5 2.5 6.1 -2.0 1.6 -1.4 -1.4 -0.6 -1.2 1.3 2.5
Sitting height 3.0 21.5 29.9 -5.3 4.5 -5.5 -5.0 -2.5 -4.6 3.8 5.3
Chronic bronchitis/emphysema (father) 3.9 4.5 6.7 -2.1 2.3 -2.6 -1.6 -1.5 -2.2 2.3 2.2
High blood pressure (mother) 0.1 0.1 0.3 0.0 0.5 0.0 -0.4 0.1 -0.3 -0.5 0.0
Body mass index (BMI) 4.1 17.6 35.2 -4.3 4.5 -4.2 -3.5 1.0 -5.9 3.7 4.8
Impedance of leg (left) 0.3 1.7 5.7 0.6 -1.1 1.0 2.4 -1.1 1.5 -0.8 -0.8
Leg predicted mass (left) 4.7 25.1 37.8 -5.2 5.3 -5.2 -5.3 0.2 -6.2 4.4 5.7
Trunk fat mass 7.2 31.0 56.9 -6.1 5.9 -5.8 -4.2 -0.1 -7.5 4.9 6.6
Waist circumference 1.3 4.9 13.4 -2.2 1.9 -2.4 -2.0 0.5 -3.7 1.4 2.3
Number of incorrect matches in round 0.3 0.6 1.7 0.5 -0.2 0.3 -1.3 -1.2 -0.1 -0.8 -0.7
Past tobacco smoking 0.2 0.4 1.2 -0.3 -0.6 -0.4 -0.6 0.9 -1.1 -0.7 -0.1
Alcohol usually taken with meals 0.5 0.9 5.2 -0.5 -0.2 -0.8 -0.3 2.3 -0.7 0.1 0.2
Nervous feelings 1.2 2.2 3.6 1.5 -1.3 1.8 1.9 1.0 0.9 -1.7 -1.5
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 3.1 0.5 -0.9 1.2 0.8 -0.9 1.8 -0.5 -0.6
Hearing difficulty/problems with background noise 2.0 3.1 5.2 1.9 -1.6 1.9 1.7 0.7 2.3 -1.7 -1.9
Hair/balding pattern: Pattern 2 0.2 0.3 0.9 -0.1 0.9 0.1 0.7 -0.1 0.5 0.7 0.5
Had menopause 0.5 0.7 3.2 0.5 -0.8 0.9 1.8 0.5 0.2 0.1 -0.3
Had other major operations 2.9 3.6 5.9 1.9 -1.7 2.4 2.0 -0.7 1.8 -2.1 -2.0
Forced vital capacity (FVC) 1.0 4.0 5.4 -2.3 1.5 -2.3 -2.1 -1.7 -2.3 1.2 2.1
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 2.1 1.1 0.1 1.0 0.4 0.0 1.4 0.1 -0.8
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 3.1 0.4 0.7 0.9 0.7 0.1 1.8 0.0 0.2
Qualifications: None of the above 1.8 3.8 6.2 -2.3 1.9 -1.0 -0.8 1.6 -2.5 2.3 2.5
Financial difficulties in last 2 years 0.9 1.2 2.1 -1.3 1.4 -1.2 -0.4 -0.4 -1.1 1.1 1.3
Mouth/teeth dental problems 0.7 1.1 3.5 1.1 -1.3 0.6 -0.2 -0.1 0.6 -1.9 -1.1
Heart attack 0.1 0.2 0.8 -0.3 -0.4 -0.1 0.1 -0.9 -0.4 0.1 0.1
Allergy 0.5 1.2 5.4 -0.4 1.0 -0.8 -1.4 -2.3 -0.2 0.7 0.3
Pain all over the body in last month 0.2 0.2 0.4 -0.6 0.3 -0.5 0.2 0.4 0.1 0.1 0.6
Diabetes (self-reported) 0.8 1.3 1.9 1.2 -1.3 1.1 0.9 0.3 1.2 -1.4 -1.2
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.6 -0.7 0.0 -0.4 -0.3 0.7 -0.8 -0.2 0.5
Medication: Ramipril 1.2 1.5 3.2 1.5 -1.2 1.2 0.2 0.4 0.5 -1.7 -1.8
Medication: Simvastatin 0.2 0.3 1.8 -0.1 -0.0 -0.1 -0.4 0.5 -1.4 -0.6 0.0
Fluid intelligence score 3.3 6.8 8.7 2.8 -2.8 2.5 2.6 0.6 2.9 -2.8 -2.9
Illnesses of siblings 0.5 0.7 3.3 0.1 0.1 0.3 0.7 1.8 1.1 0.4 0.1
Neuroticism score 0.1 0.3 0.8 -0.0 0.9 0.2 0.7 -0.0 0.7 0.4 0.3
Weight 6.6 32.6 54.2 -6.2 6.0 -6.0 -5.1 -0.1 -7.4 5.0 6.7
Impedance of arm (right) 0.2 1.0 4.0 0.5 -0.9 0.8 2.0 0.2 1.0 -0.7 -0.7
Arm fat percentage (right) 4.6 18.1 39.2 -4.5 4.5 -4.2 -2.9 0.9 -6.3 3.7 4.9
Trunk fat-free mass 2.4 13.7 20.2 -3.9 3.8 -4.0 -4.5 -0.7 -4.2 3.1 4.1
Hip circumference 9.9 42.8 67.4 -7.1 7.0 -6.9 -5.3 -1.2 -8.2 6.1 7.8
Time employed in main current job 2.0 2.3 6.2 1.3 -2.5 1.2 1.6 -0.9 0.8 -1.4 -1.7
Alcohol intake versus 10 years previously 0.8 1.2 2.1 -1.5 1.3 -1.1 -0.1 -0.6 -1.4 0.8 1.3
Father’s age at death 2.2 3.0 5.3 -1.6 2.3 -1.1 -1.4 1.1 -1.5 2.0 2.2
Worrier / anxious feelings 0.5 1.0 1.7 1.1 -0.1 1.3 1.3 0.6 0.9 -0.9 -1.1
Frequency of tiredness / lethargy in last 2 weeks 1.2 1.9 3.2 -1.5 1.3 -1.4 -0.3 -1.7 -0.8 1.8 1.6
Falls in the last year 0.4 0.6 2.7 -0.4 0.6 0.0 -0.2 1.6 -0.3 0.9 0.8
Hair/balding pattern: Pattern 3 5.4 8.1 14.6 -3.2 2.6 -3.3 -3.0 -1.0 -3.8 2.1 2.8
Number of live births 0.7 0.9 2.2 -1.0 1.1 -0.4 -0.5 -1.5 -0.9 0.2 1.4
Forced expiratory volume in 1-second (FEV1) 0.6 2.0 3.6 -1.6 0.9 -1.9 -1.2 -1.3 -1.9 0.5 1.4
Pulse rate 0.3 0.5 1.0 -0.6 0.4 -1.0 0.1 -0.9 -1.0 0.7 0.5
Happiness 1.2 1.4 4.9 0.8 -1.2 1.2 0.8 -0.6 2.2 -1.1 -0.9
Noisy workplace 2.6 3.3 5.6 -1.9 1.9 -1.4 -1.1 1.6 -2.4 1.9 2.1
Qualifications: A levels/AS levels or equivalent 1.5 3.3 5.5 2.2 -1.6 1.8 1.0 -0.8 2.4 -1.9 -2.3
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.2 0.8 -0.0 -0.1 -0.4 -0.8 0.3 0.1 -0.9 -0.2
Mouth/teeth dental problems: Dentures 0.1 0.1 0.3 -0.2 0.6 -0.1 -0.1 0.4 -0.3 0.5 0.1
Asthma 1.9 3.8 7.0 -2.2 2.0 -1.9 -1.2 0.6 -2.6 1.6 2.6
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 3.0 -0.6 1.7 -0.8 -0.9 0.3 -0.7 1.0 1.3
Medication: Cholesterol lowering 0.1 0.2 0.8 0.0 -0.3 0.2 0.3 0.5 -0.9 -0.4 0.1
Depression (self-reported) 2.1 2.5 5.6 1.6 -2.0 1.7 0.9 -0.6 2.4 -0.7 -2.0
Medication: Lansoprazole 1.8 2.1 2.9 1.6 -1.3 1.6 0.9 1.6 1.5 -0.8 -1.7
Prospective memory result 1.5 1.8 4.0 -1.5 2.0 -1.3 -0.9 0.3 -0.7 1.5 1.9
Lung cancer (father) 0.2 0.2 0.5 -0.4 0.7 0.0 -0.6 0.4 -0.3 0.6 0.6
Illnesses of mother 0.6 0.7 1.2 1.0 -0.7 0.9 0.7 1.1 0.3 -0.7 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 2.2 -1.2 0.6 -1.5 -1.3 -1.4 -1.4 0.3 0.9
Pulse wave Arterial Stiffness index 1.4 1.7 4.9 1.3 -1.1 1.4 2.2 0.7 1.1 -0.7 -1.2
Impedance of arm (left) 0.2 1.0 4.4 0.3 -0.8 0.6 2.1 -0.5 1.0 -0.6 -0.6
Arm fat mass (right) 5.9 24.2 49.1 -5.2 5.2 -5.0 -3.9 0.6 -7.0 4.2 5.7
Trunk predicted mass 2.4 14.0 19.9 -3.9 3.8 -4.0 -4.5 -0.7 -4.3 3.1 4.2
Standing height 1.5 14.8 21.0 -4.5 3.7 -4.4 -4.0 -2.0 -3.6 3.3 4.6
Length of working week for main job 1.0 1.2 2.9 -1.1 1.5 -1.0 -1.0 -0.2 -0.1 1.7 1.0
Exposure to tobacco smoke at home 0.3 0.3 1.3 -0.5 -0.0 -0.5 -0.0 -1.2 0.7 0.4 0.3
Breastfed as a baby 0.2 0.2 0.4 0.4 -0.6 0.4 -0.3 -0.4 0.4 -0.6 -0.4
Tense / ‘highly strung’ 1.8 2.9 5.2 1.8 -1.6 2.3 1.8 -0.8 2.0 -1.3 -1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.6 4.8 1.0 -0.8 1.2 2.2 -0.8 1.8 -0.7 -0.9
Hair/balding pattern: Pattern 4 0.5 1.2 2.8 0.7 -1.6 0.7 1.2 1.7 0.8 -0.4 -0.8
Birth weight of first child 0.5 0.9 5.2 0.8 -0.6 0.8 2.3 0.5 0.0 -0.0 -0.3
Peak expiratory flow (PEF) 0.3 0.6 2.2 -0.3 0.0 -0.8 -0.3 -1.5 -1.0 -0.8 0.2
Pulse wave reflection index 1.7 2.1 4.4 1.6 -1.0 2.1 1.4 0.7 1.5 -1.1 -1.6
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.5 0.8 0.0 0.5 -0.6 1.2 0.8 -0.5 -0.5
Loud music exposure frequency 1.4 1.5 2.8 1.2 -0.8 0.9 1.1 1.7 1.6 -1.1 -1.2
Qualifications: O levels/GCSEs or equivalent 1.5 2.5 4.2 2.0 -1.3 1.4 1.9 0.4 1.3 -1.8 -1.8
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 0.5 0.6 -0.7 0.6 0.2 -0.0 0.2 -0.3 -0.6
Blood clot in the leg (DVT) 0.1 0.1 0.5 -0.3 -0.1 0.2 0.3 -0.4 0.0 -0.4 0.7
Medication: Paracetamol 0.4 0.7 4.6 -0.2 -0.0 -0.3 0.5 2.1 0.1 0.6 0.1
Headache pain in last month 0.2 0.3 0.8 -0.7 0.2 -0.9 -0.6 0.5 -0.5 0.7 0.5
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 1.8 -1.0 0.9 -0.8 0.0 0.7 0.5 1.3 1.1
Glaucoma (self-reported) 1.3 1.5 3.9 1.3 -0.7 1.4 1.5 -0.3 2.0 -0.4 -1.2
Gout (self-reported) 2.3 3.1 5.9 2.2 -1.9 2.4 1.5 1.2 0.5 -1.6 -1.9
Hypothyroidism/myxoedema (self-reported) 6.2 12.1 20.2 -4.0 3.8 -3.4 -3.2 0.2 -3.4 3.6 4.5
Medication: Amlodipine 6.9 9.7 16.1 3.6 -2.4 4.0 3.1 2.1 2.4 -3.4 -3.3
Medication: Ventolin 100micrograms inhaler 0.1 0.1 0.3 -0.3 -0.1 -0.4 -0.0 0.1 -0.5 -0.5 -0.0
Birth weight 0.2 0.3 1.2 0.4 0.1 1.0 1.1 0.3 0.0 -0.3 -0.3
Chronic bronchitis/emphysema (mother) 0.9 1.0 2.7 -1.1 0.8 -0.5 -0.2 0.5 -1.4 1.0 1.6
High blood pressure (siblings) 0.5 0.7 1.8 0.9 -0.5 0.8 -0.1 -1.0 -0.1 -1.3 -1.1
Forced vital capacity (FVC), Best measure 0.5 1.8 2.8 -1.4 0.8 -1.6 -1.5 -1.7 -1.6 0.8 1.2
Body fat percentage 6.1 24.1 46.2 -5.4 5.1 -5.1 -3.3 0.2 -6.8 4.4 5.9
Leg fat percentage (right) 4.9 17.8 33.5 -4.5 4.6 -4.2 -2.8 0.0 -5.8 4.0 5.1
Arm fat-free mass (right) 3.7 18.8 26.4 -4.6 4.5 -4.8 -4.8 -0.8 -5.1 3.6 4.9
Exposure to tobacco smoke outside home 0.6 0.8 1.5 -1.2 1.0 -0.8 0.1 0.6 -0.9 0.7 1.2
Comparative body size at age 10 0.5 1.4 6.9 0.7 -0.8 0.2 -0.4 2.6 0.8 -0.8 -1.3
Number of full brothers 0.4 0.5 1.1 -0.9 0.2 -1.0 0.1 -0.5 -0.9 0.6 0.8
Worry too long after embarrassment 2.6 4.4 9.2 2.4 -1.7 2.6 1.4 0.6 3.0 -1.7 -2.2
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 3.8 1.0 -1.6 1.0 2.0 -1.1 1.0 -0.6 -1.7
Wheeze or whistling in the chest in last year 0.7 1.3 2.5 -1.5 0.8 -1.0 -1.1 1.1 -1.0 0.7 1.6
Number of children fathered 1.0 1.1 1.8 -1.3 0.9 -1.4 -0.3 1.0 -0.6 1.0 1.4
Reason for reducing amount of alcohol drunk: Health precaution 2.1 2.5 6.3 1.7 -1.6 1.3 1.1 1.1 2.5 -1.0 -1.7
Age at first live birth 1.2 2.1 3.6 1.5 -1.8 0.9 0.9 1.7 0.8 -1.6 -1.9
Pulse wave peak to peak time 1.8 2.1 6.0 -1.5 1.2 -1.6 -2.5 -0.8 -1.2 0.7 1.4
Health satisfaction 0.7 0.9 1.6 -1.0 1.2 -0.6 -1.0 0.9 -1.0 0.1 1.3
Shortness of breath walking on level ground 1.3 1.5 2.5 -1.4 0.9 -1.2 -1.5 0.9 -1.6 0.7 1.5
Qualifications: College or University degree 2.4 7.5 15.4 3.0 -2.7 2.6 2.2 -0.5 3.9 -2.5 -3.3
Eye problems/disorders: None of the above 0.6 0.7 3.4 -0.4 -0.0 -0.7 -1.8 -0.8 -1.0 -0.2 0.2
Mouth/teeth dental problems: Loose teeth 0.9 1.0 2.2 0.8 -1.1 0.6 0.5 1.5 1.2 -0.7 -1.2
Emphysema/chronic bronchitis 0.7 0.8 2.9 -0.9 0.7 -0.9 -1.7 -0.1 -1.0 0.2 0.7
Medication for pain relief, constipation, heartburn 0.1 0.2 1.1 -0.3 0.4 -0.0 0.0 -1.1 0.4 0.3 0.4
Neck or shoulder pain in last month 0.6 0.9 2.7 0.8 -0.5 0.3 0.7 1.6 1.1 -0.9 -0.9
Medication: Blood pressure 0.9 1.6 3.2 1.4 -1.6 1.1 0.7 -0.1 0.1 -1.8 -1.6
Angina (self-reported) 0.2 0.2 0.6 0.2 -0.8 0.7 -0.4 -0.3 0.2 -0.5 -0.4
Migraine (self-reported) 0.8 1.0 6.1 -0.2 -0.7 -0.4 0.9 2.5 -0.2 -0.4 -0.1
Medication: Ibuprofen 0.3 0.3 1.3 -0.0 1.1 -0.2 -0.6 0.5 -0.1 0.5 0.7
Medication: Allopurinol 1.4 1.9 4.0 1.6 -1.5 2.0 1.3 0.8 -0.2 -1.2 -1.4
Medication: Omeprazole 2.2 2.6 8.6 -1.9 0.2 -1.4 -1.5 -1.4 -2.9 0.5 1.4
Medication: Seretide 50 evohaler 0.3 0.3 2.0 0.2 -0.1 -0.0 -0.2 1.4 -0.1 -0.5 -0.2
Mean time to correctly identify matches 2.4 4.6 6.4 2.2 -2.2 2.4 1.8 1.7 2.2 -2.0 -2.5
Heart disease (mother) 0.7 0.8 2.8 -0.8 -0.1 -0.9 -1.7 -1.3 -0.4 0.6 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.9 3.4 4.6 1.7 -2.1 2.0 1.8 -0.7 2.0 -2.1 -1.9
Whole body fat mass 7.0 29.3 53.1 -5.9 5.7 -5.7 -4.2 0.2 -7.3 4.8 6.4
Leg fat mass (right) 6.6 25.7 46.4 -5.4 5.4 -5.1 -4.1 0.3 -6.8 4.7 6.0
Arm predicted mass (right) 3.6 18.3 26.9 -4.5 4.5 -4.6 -4.7 -0.7 -5.2 3.5 4.9
Pulse rate, automated reading 0.1 0.5 2.0 -0.5 -0.3 -1.1 -0.4 -0.0 -1.4 0.1 -0.1
Alcohol intake frequency. 0.2 0.5 1.6 -0.7 0.7 -0.5 0.1 0.4 -1.3 0.3 0.8
Comparative height size at age 10 1.3 7.3 12.2 -3.1 2.0 -3.3 -3.5 -0.9 -2.8 2.4 2.8
Number of full sisters 0.7 0.9 2.7 -0.8 1.6 -0.2 -0.6 -1.4 -0.4 0.4 1.1
Suffer from ‘nerves’ 0.9 1.4 2.8 1.3 -1.0 1.3 1.7 -0.0 1.5 -1.1 -1.1
Overall health rating 0.2 0.5 1.7 -0.6 0.1 -0.2 0.3 1.3 -1.1 -0.5 0.5
Chest pain or discomfort 0.3 0.4 1.2 0.3 -0.5 0.4 1.1 0.8 1.0 -0.1 -0.1
Had major operations 2.9 3.4 5.5 2.1 -2.1 2.4 1.1 0.2 1.2 -2.3 -2.1
Age at last live birth 0.5 0.8 2.3 0.7 -1.1 0.5 0.4 -0.5 0.5 -1.5 -1.0
Family relationship satisfaction 1.1 1.3 4.8 0.6 -0.5 1.2 0.4 -1.6 2.2 -0.6 -0.8
Leg pain on walking 1.1 1.4 9.0 -0.6 0.9 -0.3 0.0 3.0 -0.8 -0.1 0.8
Qualifications: NVQ or HND or HNC or equivalent 1.9 2.3 4.2 -1.6 1.8 -2.0 -1.7 -0.7 -1.5 0.9 1.5
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.8 0.2 -0.3 0.5 0.8 -0.7 -0.5 -0.9 -0.3
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.8 0.5 -0.4 0.8 1.2 -1.3 0.5 -0.2 -0.2
Medication: Aspirin 0.3 0.3 1.0 0.3 -0.7 0.3 -0.5 -1.0 -0.1 -0.5 -0.7
Supplements: Vitamin C 0.3 0.4 1.6 -0.3 -0.4 -0.6 -0.3 1.3 -1.0 -0.2 0.1
Knee pain experienced in last month 0.5 0.7 1.7 1.1 -0.2 1.0 1.0 -0.2 -0.0 -1.3 -0.9
Hypertension (Self-reported) 4.0 11.2 18.4 4.1 -3.8 3.6 2.1 0.5 2.3 -4.2 -4.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.4 1.7 -0.5 0.0 -0.5 -0.4 1.3 -1.0 -0.3 0.3
Illnesses of father: Heart disease 2.4 3.4 7.3 2.0 -2.2 1.5 0.9 0.1 1.3 -2.7 -2.4
Illnesses of siblings: Diabetes 0.7 0.9 1.9 1.2 -0.9 1.0 1.4 0.5 0.3 -0.8 -1.0
Smoking status: Previous 0.3 0.5 1.1 0.9 -0.4 0.8 1.0 -0.4 1.0 -0.0 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 1.5 -1.1 1.2 -0.8 -1.1 0.1 -0.7 -0.1 1.0
Whole body fat-free mass 3.6 20.4 28.8 -4.7 4.7 -4.8 -5.1 -0.4 -5.4 3.9 5.1
Leg fat-free mass (right) 4.5 23.9 35.4 -5.1 5.2 -5.1 -5.1 0.3 -6.0 4.4 5.6
Arm fat percentage (left) 4.7 18.8 39.3 -4.6 4.6 -4.4 -2.9 0.5 -6.3 3.8 5.1
Average weekly red wine intake 0.2 0.3 0.8 -0.5 0.9 -0.2 0.3 0.7 -0.2 0.2 0.6
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.3 -0.2 -0.3 -0.4 0.6 -0.1 -0.4 0.3 0.0
Mood swings 0.2 0.4 1.3 0.4 0.5 0.7 1.1 -0.5 0.8 0.4 -0.2
Loneliness, isolation 0.7 1.0 4.1 -0.6 1.0 -0.0 0.4 -2.0 0.5 1.2 0.7
Long-standing illness, disability or infirmity 1.5 2.3 5.6 0.9 -1.9 1.0 2.4 1.7 0.8 -1.8 -1.1
Ever had bowel cancer screening 3.0 3.6 7.5 1.8 -2.7 1.8 0.9 -1.0 1.9 -2.2 -2.1
Diabetes diagnosed by doctor 1.3 2.1 3.3 1.7 -1.5 1.5 1.2 1.0 1.3 -1.8 -1.6
Ever had stillbirth, spontaneous miscarriage or termination 1.5 1.6 4.8 1.1 -0.8 1.0 -1.0 -2.2 0.3 -1.7 -1.2
Friendships satisfaction 0.2 0.2 0.9 0.1 0.1 0.6 0.1 0.1 0.9 -0.6 -0.1
Qualifications: nursing, teaching 1.4 2.2 4.7 1.4 -1.3 1.4 2.0 -1.2 0.6 -2.2 -1.4
Commuting to job workplace: Walk 0.2 0.2 0.9 0.3 -0.3 0.0 -0.9 0.4 -0.3 0.1 -0.7
Eye problems/disorders: Cataract 1.1 1.3 3.7 1.2 -0.7 1.2 1.9 0.9 1.0 -0.6 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.7 -0.8 0.3 0.0 1.0 1.3 -0.0 0.9 0.9
Medication for cholesterol 4.5 6.8 9.4 -2.9 2.6 -3.1 -3.1 -0.9 -2.8 2.0 2.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.1 2.4 5.3 2.1 -1.3 1.5 0.9 0.5 1.4 -1.6 -2.3
Back pain experienced in last month 0.3 0.4 1.5 0.3 -0.4 0.0 0.9 1.2 0.9 -0.1 -0.4
Mineral and other dietary supplements 1.4 1.8 3.5 -1.4 1.9 -1.1 -1.6 0.8 -1.2 1.0 1.6
Breast cancer (self-reported) 0.8 1.0 1.8 0.8 -1.3 0.8 1.0 -0.1 1.1 -1.0 -1.1
Asthma (self-reported) 1.5 3.1 6.4 -2.0 1.7 -1.7 -1.2 0.7 -2.5 1.1 2.3
Osteoporosis (self-reported) 4.0 5.0 11.6 2.3 -1.6 2.8 3.4 2.1 1.5 -1.6 -1.9
Osteoarthritis (self-reported) 1.0 1.3 2.4 1.3 -1.3 1.1 0.8 0.3 1.0 -1.5 -1.3
Medication: Aspirin 0.3 0.4 0.8 0.5 -0.8 0.3 -0.5 -0.7 0.1 -0.6 -0.9
Medication: Gliclazide 0.6 0.6 1.9 -0.9 0.1 -1.0 -1.4 -0.3 -0.5 0.8 0.6
Illnesses of father: None of the above (group 1) 0.7 0.9 2.1 0.5 -1.1 1.1 1.2 0.0 1.5 -0.4 -0.7
Smoking status: Current 0.1 0.1 0.6 -0.1 0.7 0.1 -0.4 -0.1 0.5 0.2 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 2.2 0.4 -1.0 0.5 1.5 0.2 0.9 -0.7 -0.4
Whole body water mass 3.5 19.9 28.0 -4.7 4.7 -4.7 -5.1 -0.3 -5.3 3.8 5.0
Leg predicted mass (right) 4.4 23.5 35.9 -5.0 5.1 -5.1 -5.1 0.3 -6.0 4.3 5.5
Arm fat mass (left) 6.1 24.9 48.7 -5.3 5.3 -5.1 -4.0 0.4 -7.0 4.2 5.8
Number of self-reported non-cancer illnesses 1.1 2.0 3.7 1.4 -1.9 1.3 1.1 1.2 0.8 -1.7 -1.5
Average weekly champagne plus white wine intake 0.8 1.0 2.0 1.0 -1.4 0.9 -0.3 1.0 -0.1 -1.3 -1.3
Miserableness 0.3 0.5 1.0 0.8 0.4 0.8 0.8 -0.2 1.0 -0.5 -0.6
Guilty feelings 0.2 0.3 0.9 -0.4 1.0 -0.5 -0.4 0.3 0.1 0.2 0.8
Wears glasses or contact lenses 0.2 0.2 0.9 0.0 -0.5 0.3 0.9 -0.0 0.7 -0.2 -0.2
Ever taken oral contraceptive pill 2.3 2.5 4.2 1.5 -2.1 1.9 1.8 -0.6 1.0 -1.7 -1.6
Hearing aid user 0.2 0.2 0.4 -0.5 0.5 -0.6 -0.4 -0.7 -0.3 -0.1 0.4
Mother’s age at death 0.2 0.3 0.6 0.3 -0.3 0.5 0.7 0.1 0.8 -0.8 -0.4
Financial situation satisfaction 0.1 0.2 0.4 -0.6 0.3 -0.4 -0.6 -0.1 0.0 -0.1 0.5
Tinnitus: Yes, now most or all of the time 0.8 0.9 1.5 -1.0 0.9 -0.9 -0.8 -1.2 -0.9 0.9 1.2
Commuting to job workplace: Public transport 0.2 0.3 1.0 0.0 -0.3 0.0 0.5 -0.5 0.8 1.0 -0.0
Eye problems/disorders: Glaucoma 0.4 0.4 1.9 0.2 0.2 0.4 0.6 -0.8 1.4 0.6 -0.2
Medication: Blood pressure 6.0 11.5 18.0 4.2 -3.3 4.0 3.0 0.8 3.6 -2.7 -4.1
Pain type(s) experienced in last month: Hip pain 0.4 0.5 3.7 -0.1 -0.6 -0.1 -0.1 1.9 0.1 0.0 0.2
Supplements: Fish oil (including cod liver oil) 1.4 1.8 3.6 1.4 -1.9 1.3 1.2 -0.5 1.1 -1.2 -1.6
High cholesterol (Self-reported) 0.2 0.4 0.5 0.4 -0.7 0.7 0.4 0.7 -0.6 -0.7 -0.5
Medication: Bendroflumethiazide 1.4 2.1 4.2 2.1 -1.4 1.3 1.1 0.2 1.0 -1.5 -2.0
Medication: Paracetamol 0.7 1.1 7.0 0.3 -0.6 0.3 1.1 2.7 -0.1 -0.3 -0.5
Medication: Lisinopril 3.2 4.1 6.7 2.2 -2.6 1.9 1.8 -1.2 2.1 -1.9 -2.3
Medication: Atorvastatin 1.3 1.6 2.4 1.4 -1.4 1.5 1.5 -1.1 1.3 -0.6 -1.0
Illnesses of father: High blood pressure 0.7 0.9 3.1 -0.3 1.3 -0.6 -1.1 0.0 -1.8 0.6 0.6
Alcohol drinker status: Never 0.9 1.0 1.8 1.3 -1.3 0.9 0.3 -0.4 0.8 -1.2 -1.3
Ever smoked 0.3 0.6 1.6 -0.3 1.3 -0.3 -0.1 -1.1 0.7 0.9 0.6
Basal metabolic rate 4.4 24.5 36.1 -5.2 5.2 -5.3 -5.3 -0.3 -6.0 4.3 5.6
Leg fat percentage (left) 5.6 20.3 37.9 -4.9 4.9 -4.5 -3.0 0.3 -6.2 4.3 5.5
Arm fat-free mass (left) 3.8 19.4 29.5 -4.6 4.5 -4.7 -4.8 -0.2 -5.4 3.7 5.0
Number of operations (self-reported) 3.7 5.5 11.0 2.6 -2.8 2.3 1.2 0.2 2.0 -3.3 -2.8
Average weekly beer plus cider intake 0.1 0.1 0.5 0.5 0.2 0.5 -0.1 0.2 0.7 -0.0 -0.2
Irritability 0.4 0.7 2.6 0.7 0.2 0.8 1.4 -0.3 1.6 -0.0 -0.4
Risk taking 0.6 0.8 3.0 -0.6 0.9 -0.6 -0.2 -1.7 -0.1 1.0 0.9
Ever had prostate specific antigen (PSA) test 0.8 1.0 2.8 0.8 -0.5 0.6 -0.2 -1.7 1.4 -1.0 -0.9
Fractured/broken bones in last 5 years 1.0 1.3 2.1 1.1 -1.3 1.2 1.4 0.9 0.4 -1.1 -1.4
Age started oral contraceptive pill 0.4 0.5 2.2 -0.3 0.2 -0.2 -0.0 1.5 -1.0 0.6 0.6
Diastolic blood pressure, automated reading 0.8 2.4 4.9 -1.5 1.6 -1.8 -0.7 1.2 -2.2 1.5 1.5
Ever depressed for a whole week 0.5 0.6 2.3 0.4 1.5 0.6 0.6 -0.2 1.1 0.6 0.3
Unable to work because of sickness or disability 0.5 0.6 1.7 0.7 -0.8 0.7 0.6 1.3 0.7 -0.6 -0.7
Commuting to job workplace: Cycle 0.5 0.7 2.3 -0.7 0.2 -0.8 -1.5 0.6 -0.2 1.0 0.7
Myopia 1.6 2.4 3.6 1.8 -1.2 1.6 1.1 1.2 1.8 -1.5 -1.9
Vascular/heart problems diagnosed by doctor 3.5 9.5 15.9 -3.8 3.5 -3.4 -2.0 -0.4 -1.8 3.8 4.0
Cholesterol lowering medication 1.1 1.6 2.6 1.5 -1.5 1.6 1.1 -0.3 0.6 -1.4 -1.6
Medication: Omeprazole (e.g. Zanprol) 1.6 1.9 6.3 -1.6 0.2 -1.4 -1.4 -1.1 -2.5 0.1 1.3
Pain experienced in last month 0.1 0.2 0.7 0.3 -0.3 0.6 0.0 -0.9 0.5 -0.3 -0.1
Supplements: Calcium 2.0 2.2 4.4 1.7 -1.6 1.6 2.1 0.5 1.0 -1.4 -1.4
Basal cell carcinoma (self-reported) 3.0 3.6 5.5 1.9 -2.4 2.1 0.7 0.1 2.3 -2.2 -2.0
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.9 -0.1 -0.7 0.2 0.3 -0.9 -0.3 -0.3 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.2 0.2 0.7 -0.4 0.0 0.2 0.3 -0.8 -0.2 -0.2 0.8
Heart disease (siblings) 0.3 0.4 1.4 0.2 -1.2 0.2 0.2 -0.7 -0.5 -0.7 -0.4
Alcohol drinker status: Previous 2.3 2.7 6.1 1.7 -1.1 1.6 2.0 2.5 1.2 -1.0 -1.6
Pack years of smoking 0.5 0.8 2.5 0.6 -0.9 1.0 0.7 1.6 0.6 -0.9 -0.5
Impedance of whole body 0.2 0.8 4.2 0.1 -0.7 0.4 2.1 -0.7 0.9 -0.5 -0.3
Leg fat mass (left) 6.9 27.1 49.6 -5.6 5.5 -5.2 -4.2 0.6 -7.0 4.7 6.2
Arm predicted mass (left) 4.0 20.1 29.5 -4.7 4.7 -4.8 -5.0 -0.7 -5.4 3.8 5.1