TWAS hub - RSBN1L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0860	0.0230	8.8e-09	0.093	0.087	0.093	0.088	0.092	2.0e-11	9.1e-11	2.0e-11	7.0e-11	2.4e-11
2	GTEx	Brain Cerebellum	0.1400	0.0540	4.0e-03	0.125	NA	0.056	NA	0.128	1.6e-04	NA	9.3e-03	NA	1.3e-04
3	GTEx	Colon Sigmoid	0.1660	0.0660	4.6e-03	0.085	NA	0.026	NA	0.054	6.1e-04	NA	4.1e-02	NA	5.5e-03
4	GTEx	Esophagus Muscularis	0.0650	0.0310	9.7e-03	0.025	NA	0.002	NA	0.014	1.1e-02	NA	2.2e-01	NA	4.2e-02
5	NTR	Blood	0.0277	0.0109	3.7e-03	-0.001	0.008	0.001	0.008	-0.001	7.9e-01	7.4e-04	1.0e-01	1.1e-03	8.6e-01
6	ROSMAP	Brain Pre-frontal Cortex	0.0899	0.0278	1.7e-07	0.066	0.072	0.082	0.075	0.076	7.1e-09	1.3e-09	9.9e-11	6.5e-10	4.9e-10
7	YFS	Blood	0.0274	0.0096	1.1e-06	0.018	0.016	0.018	0.016	0.014	8.2e-07	4.5e-06	1.1e-06	3.4e-06	1.8e-05
8	TCGA	Brain Lower Grade Glioma	0.0180	0.0118	4.5e-03	0.021	0.018	0.014	NA	0.014	1.7e-03	3.4e-03	9.0e-03	NA	8.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Waist Hip Ratio (WHR)	16.9	75.8	112.4	9.7	-9.7	9.0	6.9	3.0	9.1	-9.1	-10.6
Hip circumference	9.9	42.8	67.4	-7.1	7.0	-6.9	-5.3	-1.2	-8.2	6.1	7.8
Trunk fat mass	7.2	31.0	56.9	-6.1	5.9	-5.8	-4.2	-0.1	-7.5	4.9	6.6
Whole body fat mass	7.0	29.3	53.1	-5.9	5.7	-5.7	-4.2	0.2	-7.3	4.8	6.4
Medication: Amlodipine	6.9	9.7	16.1	3.6	-2.4	4.0	3.1	2.1	2.4	-3.4	-3.3
Leg fat mass (left)	6.9	27.1	49.6	-5.6	5.5	-5.2	-4.2	0.6	-7.0	4.7	6.2
Weight	6.6	32.6	54.2	-6.2	6.0	-6.0	-5.1	-0.1	-7.4	5.0	6.7
Leg fat mass (right)	6.6	25.7	46.4	-5.4	5.4	-5.1	-4.1	0.3	-6.8	4.7	6.0
Trunk fat percentage	6.4	25.7	50.2	-5.6	5.3	-5.3	-3.2	0.3	-7.1	4.5	6.1
Hypothyroidism (self reported)	6.2	14.3	24.4	-4.3	4.2	-3.6	-3.0	-0.4	-4.0	3.9	4.9
Hypothyroidism/myxoedema (self-reported)	6.2	12.1	20.2	-4.0	3.8	-3.4	-3.2	0.2	-3.4	3.6	4.5
Body fat percentage	6.1	24.1	46.2	-5.4	5.1	-5.1	-3.3	0.2	-6.8	4.4	5.9
Arm fat mass (left)	6.1	24.9	48.7	-5.3	5.3	-5.1	-4.0	0.4	-7.0	4.2	5.8
Medication: Blood pressure	6.0	11.5	18.0	4.2	-3.3	4.0	3.0	0.8	3.6	-2.7	-4.1
Arm fat mass (right)	5.9	24.2	49.1	-5.2	5.2	-5.0	-3.9	0.6	-7.0	4.2	5.7
Leg fat percentage (left)	5.6	20.3	37.9	-4.9	4.9	-4.5	-3.0	0.3	-6.2	4.3	5.5
Hair/balding pattern: Pattern 3	5.4	8.1	14.6	-3.2	2.6	-3.3	-3.0	-1.0	-3.8	2.1	2.8
Leg fat percentage (right)	4.9	17.8	33.5	-4.5	4.6	-4.2	-2.8	0.0	-5.8	4.0	5.1
Leg fat-free mass (left)	4.8	25.3	38.3	-5.2	5.3	-5.3	-5.3	0.1	-6.2	4.5	5.7
Leg predicted mass (left)	4.7	25.1	37.8	-5.2	5.3	-5.2	-5.3	0.2	-6.2	4.4	5.7
Arm fat percentage (left)	4.7	18.8	39.3	-4.6	4.6	-4.4	-2.9	0.5	-6.3	3.8	5.1
Arm fat percentage (right)	4.6	18.1	39.2	-4.5	4.5	-4.2	-2.9	0.9	-6.3	3.7	4.9
Leg fat-free mass (right)	4.5	23.9	35.4	-5.1	5.2	-5.1	-5.1	0.3	-6.0	4.4	5.6
Medication for cholesterol	4.5	6.8	9.4	-2.9	2.6	-3.1	-3.1	-0.9	-2.8	2.0	2.7
Leg predicted mass (right)	4.4	23.5	35.9	-5.0	5.1	-5.1	-5.1	0.3	-6.0	4.3	5.5
Basal metabolic rate	4.4	24.5	36.1	-5.2	5.2	-5.3	-5.3	-0.3	-6.0	4.3	5.6
BMI	4.1	24.1	53.3	-5.1	5.1	-4.9	-3.9	0.6	-7.3	4.1	5.5
Body mass index (BMI)	4.1	17.6	35.2	-4.3	4.5	-4.2	-3.5	1.0	-5.9	3.7	4.8
Blood Eosinophil Count	4.0	31.1	47.5	6.3	-5.4	6.9	6.2	1.8	6.1	-4.7	-5.6
Hypertension (Self-reported)	4.0	11.2	18.4	4.1	-3.8	3.6	2.1	0.5	2.3	-4.2	-4.3
Osteoporosis (self-reported)	4.0	5.0	11.6	2.3	-1.6	2.8	3.4	2.1	1.5	-1.6	-1.9
Arm predicted mass (left)	4.0	20.1	29.5	-4.7	4.7	-4.8	-5.0	-0.7	-5.4	3.8	5.1
Chronic bronchitis/emphysema (father)	3.9	4.5	6.7	-2.1	2.3	-2.6	-1.6	-1.5	-2.2	2.3	2.2
Arm fat-free mass (left)	3.8	19.4	29.5	-4.6	4.5	-4.7	-4.8	-0.2	-5.4	3.7	5.0
Arm fat-free mass (right)	3.7	18.8	26.4	-4.6	4.5	-4.8	-4.8	-0.8	-5.1	3.6	4.9
Number of operations (self-reported)	3.7	5.5	11.0	2.6	-2.8	2.3	1.2	0.2	2.0	-3.3	-2.8
Arm predicted mass (right)	3.6	18.3	26.9	-4.5	4.5	-4.6	-4.7	-0.7	-5.2	3.5	4.9
Whole body fat-free mass	3.6	20.4	28.8	-4.7	4.7	-4.8	-5.1	-0.4	-5.4	3.9	5.1
Whole body water mass	3.5	19.9	28.0	-4.7	4.7	-4.7	-5.1	-0.3	-5.3	3.8	5.0
Vascular/heart problems diagnosed by doctor	3.5	9.5	15.9	-3.8	3.5	-3.4	-2.0	-0.4	-1.8	3.8	4.0
High blood pressure	3.4	9.6	16.5	3.8	-3.5	3.2	1.7	-0.1	2.0	-3.9	-4.1
Fluid intelligence score	3.3	6.8	8.7	2.8	-2.8	2.5	2.6	0.6	2.9	-2.8	-2.9
Medication: Lisinopril	3.2	4.1	6.7	2.2	-2.6	1.9	1.8	-1.2	2.1	-1.9	-2.3
Hand grip strength (right)	3.0	8.2	11.4	-2.8	3.4	-2.6	-3.1	-1.8	-2.7	2.9	3.3
Sitting height	3.0	21.5	29.9	-5.3	4.5	-5.5	-5.0	-2.5	-4.6	3.8	5.3
Ever had bowel cancer screening	3.0	3.6	7.5	1.8	-2.7	1.8	0.9	-1.0	1.9	-2.2	-2.1
Basal cell carcinoma (self-reported)	3.0	3.6	5.5	1.9	-2.4	2.1	0.7	0.1	2.3	-2.2	-2.0
Had other major operations	2.9	3.6	5.9	1.9	-1.7	2.4	2.0	-0.7	1.8	-2.1	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.9	3.4	4.6	1.7	-2.1	2.0	1.8	-0.7	2.0	-2.1	-1.9
Had major operations	2.9	3.4	5.5	2.1	-2.1	2.4	1.1	0.2	1.2	-2.3	-2.1
Body Mass Index (BMI) (2010)	2.8	3.8	8.5	-1.9	1.5	-2.1	-2.9	1.2	-2.6	1.0	1.6
Hand grip strength (left)	2.6	6.8	8.6	-2.6	2.9	-2.7	-2.9	-0.9	-2.5	2.9	2.9
Noisy workplace	2.6	3.3	5.6	-1.9	1.9	-1.4	-1.1	1.6	-2.4	1.9	2.1
Worry too long after embarrassment	2.6	4.4	9.2	2.4	-1.7	2.6	1.4	0.6	3.0	-1.7	-2.2
Qualifications: CSEs or equivalent	2.4	3.2	5.6	-2.1	1.9	-1.9	-0.9	-0.2	-2.4	2.0	1.8
Trunk fat-free mass	2.4	13.7	20.2	-3.9	3.8	-4.0	-4.5	-0.7	-4.2	3.1	4.1
Trunk predicted mass	2.4	14.0	19.9	-3.9	3.8	-4.0	-4.5	-0.7	-4.3	3.1	4.2
Qualifications: College or University degree	2.4	7.5	15.4	3.0	-2.7	2.6	2.2	-0.5	3.9	-2.5	-3.3
Mean time to correctly identify matches	2.4	4.6	6.4	2.2	-2.2	2.4	1.8	1.7	2.2	-2.0	-2.5
Illnesses of father: Heart disease	2.4	3.4	7.3	2.0	-2.2	1.5	0.9	0.1	1.3	-2.7	-2.4
Systolic Blood Pressure	2.3	11.5	23.8	4.4	-3.5	3.4	1.7	0.3	1.8	-4.2	-4.9
Eye problems/disorders: Diabetes related eye disease	2.3	2.5	3.5	1.7	-1.8	1.9	1.6	0.0	1.5	-1.7	-1.8
Gout (self-reported)	2.3	3.1	5.9	2.2	-1.9	2.4	1.5	1.2	0.5	-1.6	-1.9
Ever taken oral contraceptive pill	2.3	2.5	4.2	1.5	-2.1	1.9	1.8	-0.6	1.0	-1.7	-1.6
Alcohol drinker status: Previous	2.3	2.7	6.1	1.7	-1.1	1.6	2.0	2.5	1.2	-1.0	-1.6
Hayfever, allergic rhinitis or eczema	2.2	4.8	7.5	2.0	-2.4	2.0	2.3	2.7	2.1	-1.8	-2.2
Father’s age at death	2.2	3.0	5.3	-1.6	2.3	-1.1	-1.4	1.1	-1.5	2.0	2.2
Medication: Omeprazole	2.2	2.6	8.6	-1.9	0.2	-1.4	-1.5	-1.4	-2.9	0.5	1.4
Alzheimer’s Disease (in mother)	2.1	2.5	3.9	-1.2	1.8	-1.3	-1.5	-1.8	-1.4	2.0	1.4
Depression (self-reported)	2.1	2.5	5.6	1.6	-2.0	1.7	0.9	-0.6	2.4	-0.7	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	6.3	1.7	-1.6	1.3	1.1	1.1	2.5	-1.0	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.4	5.3	2.1	-1.3	1.5	0.9	0.5	1.4	-1.6	-2.3
Mean Putamen Volume	2.0	2.3	3.5	1.2	-1.7	1.2	1.3	1.9	1.6	-1.6	-1.4
Hearing difficulty/problems with background noise	2.0	3.1	5.2	1.9	-1.6	1.9	1.7	0.7	2.3	-1.7	-1.9
Time employed in main current job	2.0	2.3	6.2	1.3	-2.5	1.2	1.6	-0.9	0.8	-1.4	-1.7
Supplements: Calcium	2.0	2.2	4.4	1.7	-1.6	1.6	2.1	0.5	1.0	-1.4	-1.4
Alzheimer’s Disease (including proxy)	1.9	2.8	6.4	-1.3	2.5	-1.7	-1.4	0.1	-0.9	2.3	1.7
Asthma	1.9	3.8	7.0	-2.2	2.0	-1.9	-1.2	0.6	-2.6	1.6	2.6
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	4.2	-1.6	1.8	-2.0	-1.7	-0.7	-1.5	0.9	1.5
Respiratory disease	1.8	4.0	9.9	-2.2	2.3	-1.6	-1.3	-0.3	-3.1	1.2	2.5
Qualifications: None of the above	1.8	3.8	6.2	-2.3	1.9	-1.0	-0.8	1.6	-2.5	2.3	2.5
Medication: Lansoprazole	1.8	2.1	2.9	1.6	-1.3	1.6	0.9	1.6	1.5	-0.8	-1.7
Tense / ‘highly strung’	1.8	2.9	5.2	1.8	-1.6	2.3	1.8	-0.8	2.0	-1.3	-1.6
Pulse wave peak to peak time	1.8	2.1	6.0	-1.5	1.2	-1.6	-2.5	-0.8	-1.2	0.7	1.4
Cardiovascular Disease	1.7	5.5	12.0	2.7	-2.6	2.4	1.4	1.2	0.5	-3.5	-3.0
Pulse wave reflection index	1.7	2.1	4.4	1.6	-1.0	2.1	1.4	0.7	1.5	-1.1	-1.6
Schizophrenia vs Biploar Disorder	1.6	2.1	3.4	1.8	-1.3	1.9	0.9	0.2	1.0	-1.8	-1.9
Myopia	1.6	2.4	3.6	1.8	-1.2	1.6	1.1	1.2	1.8	-1.5	-1.9
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	6.3	-1.6	0.2	-1.4	-1.4	-1.1	-2.5	0.1	1.3
Ulcerative Colitis (UC)	1.5	2.8	4.7	2.1	-1.1	2.2	1.7	0.7	2.1	-1.5	-1.4
Crohns Disease (2012)	1.5	2.5	3.0	-1.5	1.6	-1.6	-1.7	1.7	-1.7	1.1	1.6
Medication for hormone replacement therapy	1.5	1.7	4.2	-1.4	1.7	-0.9	0.1	-0.3	-0.6	1.7	2.0
Supplements: Zinc	1.5	1.7	2.5	-1.4	0.9	-1.1	-1.5	-1.1	-1.0	1.6	1.5
Medication: Levothyroxine sodium	1.5	2.5	6.1	-2.0	1.6	-1.4	-1.4	-0.6	-1.2	1.3	2.5
Qualifications: A levels/AS levels or equivalent	1.5	3.3	5.5	2.2	-1.6	1.8	1.0	-0.8	2.4	-1.9	-2.3
Prospective memory result	1.5	1.8	4.0	-1.5	2.0	-1.3	-0.9	0.3	-0.7	1.5	1.9
Standing height	1.5	14.8	21.0	-4.5	3.7	-4.4	-4.0	-2.0	-3.6	3.3	4.6
Qualifications: O levels/GCSEs or equivalent	1.5	2.5	4.2	2.0	-1.3	1.4	1.9	0.4	1.3	-1.8	-1.8
Long-standing illness, disability or infirmity	1.5	2.3	5.6	0.9	-1.9	1.0	2.4	1.7	0.8	-1.8	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	4.8	1.1	-0.8	1.0	-1.0	-2.2	0.3	-1.7	-1.2
Asthma (self-reported)	1.5	3.1	6.4	-2.0	1.7	-1.7	-1.2	0.7	-2.5	1.1	2.3
Verbal and Numeric Reasoning (VNR)	1.4	3.3	7.0	1.9	-1.9	1.5	0.9	1.3	1.7	-2.6	-2.1
Allergy or Eczema	1.4	3.6	6.3	1.5	-2.1	1.7	2.1	2.5	1.8	-1.6	-1.7
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	2.9	1.3	-1.7	1.3	1.3	-0.1	1.7	-1.7	-1.2
Pulse wave Arterial Stiffness index	1.4	1.7	4.9	1.3	-1.1	1.4	2.2	0.7	1.1	-0.7	-1.2
Loud music exposure frequency	1.4	1.5	2.8	1.2	-0.8	0.9	1.1	1.7	1.6	-1.1	-1.2
Medication: Allopurinol	1.4	1.9	4.0	1.6	-1.5	2.0	1.3	0.8	-0.2	-1.2	-1.4
Qualifications: nursing, teaching	1.4	2.2	4.7	1.4	-1.3	1.4	2.0	-1.2	0.6	-2.2	-1.4
Mineral and other dietary supplements	1.4	1.8	3.5	-1.4	1.9	-1.1	-1.6	0.8	-1.2	1.0	1.6
Supplements: Fish oil (including cod liver oil)	1.4	1.8	3.6	1.4	-1.9	1.3	1.2	-0.5	1.1	-1.2	-1.6
Medication: Bendroflumethiazide	1.4	2.1	4.2	2.1	-1.4	1.3	1.1	0.2	1.0	-1.5	-2.0
Worry (Nagel 2018)	1.3	2.7	4.8	1.7	-1.4	1.9	2.2	0.5	2.1	-1.3	-1.6
Major Depression (MDD)	1.3	1.6	4.5	0.9	-1.1	1.2	1.3	2.1	0.4	-1.5	-1.0
LDL Cholesterol	1.3	2.0	4.3	-1.8	1.4	-1.1	-0.1	0.9	-1.8	1.2	2.1
Lupus	1.3	2.0	3.4	1.3	-1.8	1.8	1.8	1.1	0.6	-1.2	-1.0
Rheumatoid Arthritis	1.3	1.7	4.9	-1.0	1.7	-0.8	-1.0	0.4	-2.2	1.1	1.5
Medication: Atenolol	1.3	1.7	3.3	1.3	-1.2	1.5	1.3	-0.6	1.8	-0.9	-1.3
Waist circumference	1.3	4.9	13.4	-2.2	1.9	-2.4	-2.0	0.5	-3.7	1.4	2.3
Glaucoma (self-reported)	1.3	1.5	3.9	1.3	-0.7	1.4	1.5	-0.3	2.0	-0.4	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	3.8	1.0	-1.6	1.0	2.0	-1.1	1.0	-0.6	-1.7
Shortness of breath walking on level ground	1.3	1.5	2.5	-1.4	0.9	-1.2	-1.5	0.9	-1.6	0.7	1.5
Comparative height size at age 10	1.3	7.3	12.2	-3.1	2.0	-3.3	-3.5	-0.9	-2.8	2.4	2.8
Diabetes diagnosed by doctor	1.3	2.1	3.3	1.7	-1.5	1.5	1.2	1.0	1.3	-1.8	-1.6
Medication: Atorvastatin	1.3	1.6	2.4	1.4	-1.4	1.5	1.5	-1.1	1.3	-0.6	-1.0
Age at First Birth	1.2	1.7	3.8	1.4	-1.5	1.5	0.7	0.3	0.8	-2.0	-1.5
Coronary Artery Disease (CAD)	1.2	1.4	3.5	1.1	-1.9	0.9	0.9	-0.7	0.9	-1.4	-1.3
HDL Cholesterol	1.2	2.0	3.6	-1.4	1.9	-1.4	-1.5	-1.1	-0.6	1.6	1.5
Nervous feelings	1.2	2.2	3.6	1.5	-1.3	1.8	1.9	1.0	0.9	-1.7	-1.5
Medication: Ramipril	1.2	1.5	3.2	1.5	-1.2	1.2	0.2	0.4	0.5	-1.7	-1.8
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.2	-1.5	1.3	-1.4	-0.3	-1.7	-0.8	1.8	1.6
Happiness	1.2	1.4	4.9	0.8	-1.2	1.2	0.8	-0.6	2.2	-1.1	-0.9
Age at first live birth	1.2	2.1	3.6	1.5	-1.8	0.9	0.9	1.7	0.8	-1.6	-1.9
Height	1.1	21.7	36.2	-6.0	3.7	-5.6	-4.9	-1.0	-4.1	4.0	5.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.6	4.8	1.0	-0.8	1.2	2.2	-0.8	1.8	-0.7	-0.9
Family relationship satisfaction	1.1	1.3	4.8	0.6	-0.5	1.2	0.4	-1.6	2.2	-0.6	-0.8
Leg pain on walking	1.1	1.4	9.0	-0.6	0.9	-0.3	0.0	3.0	-0.8	-0.1	0.8
Eye problems/disorders: Cataract	1.1	1.3	3.7	1.2	-0.7	1.2	1.9	0.9	1.0	-0.6	-0.9
Number of self-reported non-cancer illnesses	1.1	2.0	3.7	1.4	-1.9	1.3	1.1	1.2	0.8	-1.7	-1.5
Cholesterol lowering medication	1.1	1.6	2.6	1.5	-1.5	1.6	1.1	-0.3	0.6	-1.4	-1.6
Reaction Time	1.0	1.9	3.1	1.4	-1.1	1.6	1.5	1.4	1.1	-1.1	-1.8
Serious illness, injury or assault to yourself	1.0	1.2	2.8	1.4	-0.9	1.3	-0.1	-0.4	0.8	-1.1	-1.7
Forced vital capacity (FVC)	1.0	4.0	5.4	-2.3	1.5	-2.3	-2.1	-1.7	-2.3	1.2	2.1
Length of working week for main job	1.0	1.2	2.9	-1.1	1.5	-1.0	-1.0	-0.2	-0.1	1.7	1.0
Number of children fathered	1.0	1.1	1.8	-1.3	0.9	-1.4	-0.3	1.0	-0.6	1.0	1.4
Osteoarthritis (self-reported)	1.0	1.3	2.4	1.3	-1.3	1.1	0.8	0.3	1.0	-1.5	-1.3
Fractured/broken bones in last 5 years	1.0	1.3	2.1	1.1	-1.3	1.2	1.4	0.9	0.4	-1.1	-1.4
Fed-up feelings	0.9	1.6	3.0	-1.4	1.7	-1.3	-0.5	-0.4	-0.7	1.6	1.7
Supplements: Glucosamine	0.9	1.2	4.0	0.8	-1.1	0.6	1.2	-2.0	0.8	-0.9	-0.8
Financial difficulties in last 2 years	0.9	1.2	2.1	-1.3	1.4	-1.2	-0.4	-0.4	-1.1	1.1	1.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.7	-1.1	0.8	-0.5	-0.2	0.5	-1.4	1.0	1.6
Mouth/teeth dental problems: Loose teeth	0.9	1.0	2.2	0.8	-1.1	0.6	0.5	1.5	1.2	-0.7	-1.2
Medication: Blood pressure	0.9	1.6	3.2	1.4	-1.6	1.1	0.7	-0.1	0.1	-1.8	-1.6
Suffer from ‘nerves’	0.9	1.4	2.8	1.3	-1.0	1.3	1.7	-0.0	1.5	-1.1	-1.1
Alcohol drinker status: Never	0.9	1.0	1.8	1.3	-1.3	0.9	0.3	-0.4	0.8	-1.2	-1.3
Fasting Glucose	0.8	0.9	1.9	-1.3	0.7	-1.4	-0.9	0.2	-0.9	0.7	1.1
Type 2 Diabetes (T2D) (2018)	0.8	1.4	2.9	1.4	-1.7	1.2	1.2	0.3	0.4	-1.3	-1.4
Relative age of first facial hair	0.8	1.7	4.0	1.4	-0.8	2.0	1.3	-0.5	1.8	-0.8	-1.0
Medication: Metformin	0.8	1.1	1.5	1.0	-1.2	1.0	0.7	1.1	1.0	-1.1	-1.0
Severe depression (siblings)	0.8	0.8	1.6	0.8	-0.8	1.0	0.7	0.8	1.0	-1.3	-0.7
Diabetes (self-reported)	0.8	1.3	1.9	1.2	-1.3	1.1	0.9	0.3	1.2	-1.4	-1.2
Alcohol intake versus 10 years previously	0.8	1.2	2.1	-1.5	1.3	-1.1	-0.1	-0.6	-1.4	0.8	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	3.0	-0.6	1.7	-0.8	-0.9	0.3	-0.7	1.0	1.3
Migraine (self-reported)	0.8	1.0	6.1	-0.2	-0.7	-0.4	0.9	2.5	-0.2	-0.4	-0.1
Breast cancer (self-reported)	0.8	1.0	1.8	0.8	-1.3	0.8	1.0	-0.1	1.1	-1.0	-1.1
Average weekly champagne plus white wine intake	0.8	1.0	2.0	1.0	-1.4	0.9	-0.3	1.0	-0.1	-1.3	-1.3
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.5	-1.0	0.9	-0.9	-0.8	-1.2	-0.9	0.9	1.2
Ever had prostate specific antigen (PSA) test	0.8	1.0	2.8	0.8	-0.5	0.6	-0.2	-1.7	1.4	-1.0	-0.9
Diastolic blood pressure, automated reading	0.8	2.4	4.9	-1.5	1.6	-1.8	-0.7	1.2	-2.2	1.5	1.5
Chronotype (morning person)	0.7	1.6	6.0	1.0	-1.5	0.7	-0.2	1.1	0.2	-2.5	-1.4
Tanning	0.7	8.0	12.2	-2.4	3.5	-2.2	-3.4	-1.8	-3.5	2.4	2.9
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.2	-1.3	0.6	-1.1	-0.4	-0.3	-0.1	1.1	1.5
Townsend deprivation index at recruitment	0.7	1.0	1.8	-1.3	1.0	-0.7	-0.9	0.2	-1.3	1.2	1.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.7	-0.4	0.6	-0.3	-1.1	-1.6	-0.9	-0.6	0.4
Mouth/teeth dental problems	0.7	1.1	3.5	1.1	-1.3	0.6	-0.2	-0.1	0.6	-1.9	-1.1
Number of live births	0.7	0.9	2.2	-1.0	1.1	-0.4	-0.5	-1.5	-0.9	0.2	1.4
Wheeze or whistling in the chest in last year	0.7	1.3	2.5	-1.5	0.8	-1.0	-1.1	1.1	-1.0	0.7	1.6
Health satisfaction	0.7	0.9	1.6	-1.0	1.2	-0.6	-1.0	0.9	-1.0	0.1	1.3
Emphysema/chronic bronchitis	0.7	0.8	2.9	-0.9	0.7	-0.9	-1.7	-0.1	-1.0	0.2	0.7
Heart disease (mother)	0.7	0.8	2.8	-0.8	-0.1	-0.9	-1.7	-1.3	-0.4	0.6	0.5
Number of full sisters	0.7	0.9	2.7	-0.8	1.6	-0.2	-0.6	-1.4	-0.4	0.4	1.1
Illnesses of siblings: Diabetes	0.7	0.9	1.9	1.2	-0.9	1.0	1.4	0.5	0.3	-0.8	-1.0
Loneliness, isolation	0.7	1.0	4.1	-0.6	1.0	-0.0	0.4	-2.0	0.5	1.2	0.7
Illnesses of father: None of the above (group 1)	0.7	0.9	2.1	0.5	-1.1	1.1	1.2	0.0	1.5	-0.4	-0.7
Medication: Paracetamol	0.7	1.1	7.0	0.3	-0.6	0.3	1.1	2.7	-0.1	-0.3	-0.5
Illnesses of father: High blood pressure	0.7	0.9	3.1	-0.3	1.3	-0.6	-1.1	0.0	-1.8	0.6	0.6
Neuroticism (Nagel 2018)	0.6	1.5	4.2	1.1	-0.7	1.4	1.4	-0.7	2.0	-0.8	-1.0
Crohns Disease (2017)	0.6	1.2	2.4	-0.8	1.1	-0.8	-1.3	1.6	-0.5	1.4	1.0
HbA1C	0.6	0.7	3.6	-0.5	0.1	-0.8	-1.9	-0.7	-0.9	0.1	0.1
Pack years adult smoking proportion	0.6	0.9	2.0	0.8	-0.9	1.2	0.8	1.4	0.9	-1.0	-0.7
Maternal smoking around birth	0.6	0.9	1.6	-0.9	1.3	-0.7	-0.3	1.0	0.0	1.3	1.1
Multivitamins +/- minerals	0.6	0.7	4.4	-0.0	-0.7	-0.3	0.8	-2.1	0.1	-0.3	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.1	0.5	-0.9	1.2	0.8	-0.9	1.8	-0.5	-0.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	3.6	-1.6	0.9	-1.9	-1.2	-1.3	-1.9	0.5	1.4
Illnesses of mother	0.6	0.7	1.2	1.0	-0.7	0.9	0.7	1.1	0.3	-0.7	-1.0
Exposure to tobacco smoke outside home	0.6	0.8	1.5	-1.2	1.0	-0.8	0.1	0.6	-0.9	0.7	1.2
Eye problems/disorders: None of the above	0.6	0.7	3.4	-0.4	-0.0	-0.7	-1.8	-0.8	-1.0	-0.2	0.2
Neck or shoulder pain in last month	0.6	0.9	2.7	0.8	-0.5	0.3	0.7	1.6	1.1	-0.9	-0.9
Medication: Gliclazide	0.6	0.6	1.9	-0.9	0.1	-1.0	-1.4	-0.3	-0.5	0.8	0.6
Risk taking	0.6	0.8	3.0	-0.6	0.9	-0.6	-0.2	-1.7	-0.1	1.0	0.9
Intelligence (Savage-Jansen 2018)	0.5	1.5	3.8	1.3	-1.5	0.9	0.3	0.4	1.5	-1.9	-1.2
Schizophrenia (2014)	0.5	1.2	1.9	1.1	-1.4	1.3	1.0	0.2	0.9	-1.0	-1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.8	0.6	-0.5	0.2	0.9	0.5	0.4	-1.3	-0.8
Average weekly spirits intake	0.5	0.6	1.2	-0.7	0.6	-1.1	-0.9	-1.0	-0.2	1.0	0.5
Ever had hysterectomy (womb removed)	0.5	0.5	1.1	0.9	-0.9	1.0	0.7	-0.1	0.3	-0.5	-0.8
Vitamin and mineral supplements	0.5	0.6	2.1	0.7	0.5	1.1	-0.5	1.5	0.8	0.0	-0.2
Impedance of leg (right)	0.5	2.4	6.3	1.0	-1.5	1.3	2.5	-1.2	2.0	-1.2	-1.2
Relative age voice broke	0.5	0.8	2.9	0.4	-0.2	0.8	1.7	-0.7	1.2	0.9	0.0
Alcohol usually taken with meals	0.5	0.9	5.2	-0.5	-0.2	-0.8	-0.3	2.3	-0.7	0.1	0.2
Had menopause	0.5	0.7	3.2	0.5	-0.8	0.9	1.8	0.5	0.2	0.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.1	0.4	0.7	0.9	0.7	0.1	1.8	0.0	0.2
Allergy	0.5	1.2	5.4	-0.4	1.0	-0.8	-1.4	-2.3	-0.2	0.7	0.3
Illnesses of siblings	0.5	0.7	3.3	0.1	0.1	0.3	0.7	1.8	1.1	0.4	0.1
Worrier / anxious feelings	0.5	1.0	1.7	1.1	-0.1	1.3	1.3	0.6	0.9	-0.9	-1.1
Hair/balding pattern: Pattern 4	0.5	1.2	2.8	0.7	-1.6	0.7	1.2	1.7	0.8	-0.4	-0.8
Birth weight of first child	0.5	0.9	5.2	0.8	-0.6	0.8	2.3	0.5	0.0	-0.0	-0.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.8	-1.0	0.9	-0.8	0.0	0.7	0.5	1.3	1.1
High blood pressure (siblings)	0.5	0.7	1.8	0.9	-0.5	0.8	-0.1	-1.0	-0.1	-1.3	-1.1
Forced vital capacity (FVC), Best measure	0.5	1.8	2.8	-1.4	0.8	-1.6	-1.5	-1.7	-1.6	0.8	1.2
Comparative body size at age 10	0.5	1.4	6.9	0.7	-0.8	0.2	-0.4	2.6	0.8	-0.8	-1.3
Age at last live birth	0.5	0.8	2.3	0.7	-1.1	0.5	0.4	-0.5	0.5	-1.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.8	0.5	-0.4	0.8	1.2	-1.3	0.5	-0.2	-0.2
Knee pain experienced in last month	0.5	0.7	1.7	1.1	-0.2	1.0	1.0	-0.2	-0.0	-1.3	-0.9
Ever depressed for a whole week	0.5	0.6	2.3	0.4	1.5	0.6	0.6	-0.2	1.1	0.6	0.3
Unable to work because of sickness or disability	0.5	0.6	1.7	0.7	-0.8	0.7	0.6	1.3	0.7	-0.6	-0.7
Commuting to job workplace: Cycle	0.5	0.7	2.3	-0.7	0.2	-0.8	-1.5	0.6	-0.2	1.0	0.7
Pack years of smoking	0.5	0.8	2.5	0.6	-0.9	1.0	0.7	1.6	0.6	-0.9	-0.5
Schizophrenia (2018)	0.4	0.8	1.3	0.4	-1.0	1.1	1.1	1.1	0.5	-0.7	-0.8
Alzheimer’s Disease (in father)	0.4	0.4	1.3	0.1	1.1	-0.4	-0.8	0.6	0.8	0.4	0.2
Ovarian Cancer	0.4	0.5	3.2	-0.0	0.1	0.2	-0.5	-1.8	-0.2	-0.6	0.2
Prostate Cancer	0.4	0.5	2.6	-0.4	-0.8	0.2	1.6	-0.4	-0.7	-0.6	0.1
Hearing difficulty/problems: Yes	0.4	0.5	1.5	-0.8	0.7	-0.8	-1.2	0.0	-0.5	0.6	0.7
Average weekly fortified wine intake	0.4	0.5	1.1	-0.4	1.0	-0.0	0.4	-1.0	0.4	0.9	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.0	1.2	-0.2	1.1	0.7	-0.4	1.4	-0.4	-1.1
Falls in the last year	0.4	0.6	2.7	-0.4	0.6	0.0	-0.2	1.6	-0.3	0.9	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	2.2	-1.2	0.6	-1.5	-1.3	-1.4	-1.4	0.3	0.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.5	0.8	0.0	0.5	-0.6	1.2	0.8	-0.5	-0.5
Medication: Paracetamol	0.4	0.7	4.6	-0.2	-0.0	-0.3	0.5	2.1	0.1	0.6	0.1
Number of full brothers	0.4	0.5	1.1	-0.9	0.2	-1.0	0.1	-0.5	-0.9	0.6	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.7	-0.5	0.0	-0.5	-0.4	1.3	-1.0	-0.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.8	1.5	-1.1	1.2	-0.8	-1.1	0.1	-0.7	-0.1	1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.7	-0.8	0.3	0.0	1.0	1.3	-0.0	0.9	0.9
Eye problems/disorders: Glaucoma	0.4	0.4	1.9	0.2	0.2	0.4	0.6	-0.8	1.4	0.6	-0.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	3.7	-0.1	-0.6	-0.1	-0.1	1.9	0.1	0.0	0.2
Irritability	0.4	0.7	2.6	0.7	0.2	0.8	1.4	-0.3	1.6	-0.0	-0.4
Age started oral contraceptive pill	0.4	0.5	2.2	-0.3	0.2	-0.2	-0.0	1.5	-1.0	0.6	0.6
Primary Biliary Cirrhosis	0.3	0.4	1.4	0.0	-0.0	0.2	-1.2	-1.1	0.0	-0.5	-0.2
Blood Red Count	0.3	3.0	6.2	-1.5	1.9	-1.9	-2.1	-0.6	-2.5	0.8	1.6
Neuroticism	0.3	0.8	3.1	0.5	-0.1	0.9	1.8	-0.1	1.4	-0.2	-0.3
Angina	0.3	0.3	0.7	0.4	-0.9	0.8	-0.4	-0.2	0.5	-0.7	-0.5
Medication: Co-codamol	0.3	0.4	2.0	-0.3	0.3	-0.5	-0.1	-1.4	0.5	0.4	0.3
Diabetes (mother)	0.3	0.4	2.3	-0.3	0.3	-0.7	-0.5	-0.1	-1.5	-0.2	0.2
Taking other prescription medications	0.3	0.5	1.5	0.5	-0.0	0.8	0.7	1.2	-0.2	-1.0	-0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.1	0.5	0.0	0.9	1.0	0.2	0.8	0.3	-0.2
Impedance of leg (left)	0.3	1.7	5.7	0.6	-1.1	1.0	2.4	-1.1	1.5	-0.8	-0.8
Number of incorrect matches in round	0.3	0.6	1.7	0.5	-0.2	0.3	-1.3	-1.2	-0.1	-0.8	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.1	1.1	0.1	1.0	0.4	0.0	1.4	0.1	-0.8
Pulse rate	0.3	0.5	1.0	-0.6	0.4	-1.0	0.1	-0.9	-1.0	0.7	0.5
Exposure to tobacco smoke at home	0.3	0.3	1.3	-0.5	-0.0	-0.5	-0.0	-1.2	0.7	0.4	0.3
Peak expiratory flow (PEF)	0.3	0.6	2.2	-0.3	0.0	-0.8	-0.3	-1.5	-1.0	-0.8	0.2
Medication: Ibuprofen	0.3	0.3	1.3	-0.0	1.1	-0.2	-0.6	0.5	-0.1	0.5	0.7
Medication: Seretide 50 evohaler	0.3	0.3	2.0	0.2	-0.1	-0.0	-0.2	1.4	-0.1	-0.5	-0.2
Chest pain or discomfort	0.3	0.4	1.2	0.3	-0.5	0.4	1.1	0.8	1.0	-0.1	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.8	0.2	-0.3	0.5	0.8	-0.7	-0.5	-0.9	-0.3
Medication: Aspirin	0.3	0.3	1.0	0.3	-0.7	0.3	-0.5	-1.0	-0.1	-0.5	-0.7
Supplements: Vitamin C	0.3	0.4	1.6	-0.3	-0.4	-0.6	-0.3	1.3	-1.0	-0.2	0.1
Smoking status: Previous	0.3	0.5	1.1	0.9	-0.4	0.8	1.0	-0.4	1.0	-0.0	-0.6
Back pain experienced in last month	0.3	0.4	1.5	0.3	-0.4	0.0	0.9	1.2	0.9	-0.1	-0.4
Medication: Aspirin	0.3	0.4	0.8	0.5	-0.8	0.3	-0.5	-0.7	0.1	-0.6	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.2	0.4	-1.0	0.5	1.5	0.2	0.9	-0.7	-0.4
Miserableness	0.3	0.5	1.0	0.8	0.4	0.8	0.8	-0.2	1.0	-0.5	-0.6
Ever smoked	0.3	0.6	1.6	-0.3	1.3	-0.3	-0.1	-1.1	0.7	0.9	0.6
Heart disease (siblings)	0.3	0.4	1.4	0.2	-1.2	0.2	0.2	-0.7	-0.5	-0.7	-0.4
Depressed Affect (Nagel 2018)	0.2	0.4	1.3	-0.3	0.8	0.1	0.3	-1.1	0.5	0.7	0.6
Irritable Bowel Disease (IBD)	0.2	0.5	2.3	0.8	-0.0	0.8	0.2	1.5	0.8	-0.0	-0.2
Triglycerides	0.2	0.4	0.9	0.4	-0.6	0.8	0.9	-0.5	-0.7	-0.5	0.1
Blood Platelet Count	0.2	2.9	10.6	1.6	-0.8	1.6	1.7	3.2	0.5	-1.6	-1.1
Blood White Count	0.2	1.8	9.4	0.8	0.1	1.2	1.7	3.1	0.0	-0.4	-0.2
Sensitivity / hurt feelings	0.2	0.4	1.4	-0.2	1.2	-0.1	-0.5	-1.1	0.3	0.4	0.4
Diabetes (father)	0.2	0.3	0.6	0.5	0.7	0.5	-0.4	0.1	0.2	-0.7	-0.5
Current tobacco smoking	0.2	0.3	0.8	0.4	0.0	0.6	0.0	0.6	0.9	-0.4	-0.4
Age when periods started (menarche)	0.2	0.6	1.8	-0.6	1.1	-0.0	-0.4	-1.3	-0.4	0.3	1.0
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.7	-0.2	0.8	-0.3	-0.8	-0.2	-0.2	0.7	0.4
Past tobacco smoking	0.2	0.4	1.2	-0.3	-0.6	-0.4	-0.6	0.9	-1.1	-0.7	-0.1
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	-0.1	0.9	0.1	0.7	-0.1	0.5	0.7	0.5
Pain all over the body in last month	0.2	0.2	0.4	-0.6	0.3	-0.5	0.2	0.4	0.1	0.1	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.6	-0.7	0.0	-0.4	-0.3	0.7	-0.8	-0.2	0.5
Medication: Simvastatin	0.2	0.3	1.8	-0.1	-0.0	-0.1	-0.4	0.5	-1.4	-0.6	0.0
Impedance of arm (right)	0.2	1.0	4.0	0.5	-0.9	0.8	2.0	0.2	1.0	-0.7	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.8	-0.0	-0.1	-0.4	-0.8	0.3	0.1	-0.9	-0.2
Lung cancer (father)	0.2	0.2	0.5	-0.4	0.7	0.0	-0.6	0.4	-0.3	0.6	0.6
Impedance of arm (left)	0.2	1.0	4.4	0.3	-0.8	0.6	2.1	-0.5	1.0	-0.6	-0.6
Breastfed as a baby	0.2	0.2	0.4	0.4	-0.6	0.4	-0.3	-0.4	0.4	-0.6	-0.4
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.5	0.6	-0.7	0.6	0.2	-0.0	0.2	-0.3	-0.6
Headache pain in last month	0.2	0.3	0.8	-0.7	0.2	-0.9	-0.6	0.5	-0.5	0.7	0.5
Birth weight	0.2	0.3	1.2	0.4	0.1	1.0	1.1	0.3	0.0	-0.3	-0.3
Angina (self-reported)	0.2	0.2	0.6	0.2	-0.8	0.7	-0.4	-0.3	0.2	-0.5	-0.4
Alcohol intake frequency.	0.2	0.5	1.6	-0.7	0.7	-0.5	0.1	0.4	-1.3	0.3	0.8
Overall health rating	0.2	0.5	1.7	-0.6	0.1	-0.2	0.3	1.3	-1.1	-0.5	0.5
Average weekly red wine intake	0.2	0.3	0.8	-0.5	0.9	-0.2	0.3	0.7	-0.2	0.2	0.6
Mood swings	0.2	0.4	1.3	0.4	0.5	0.7	1.1	-0.5	0.8	0.4	-0.2
Friendships satisfaction	0.2	0.2	0.9	0.1	0.1	0.6	0.1	0.1	0.9	-0.6	-0.1
Commuting to job workplace: Walk	0.2	0.2	0.9	0.3	-0.3	0.0	-0.9	0.4	-0.3	0.1	-0.7
Guilty feelings	0.2	0.3	0.9	-0.4	1.0	-0.5	-0.4	0.3	0.1	0.2	0.8
Wears glasses or contact lenses	0.2	0.2	0.9	0.0	-0.5	0.3	0.9	-0.0	0.7	-0.2	-0.2
Hearing aid user	0.2	0.2	0.4	-0.5	0.5	-0.6	-0.4	-0.7	-0.3	-0.1	0.4
Mother’s age at death	0.2	0.3	0.6	0.3	-0.3	0.5	0.7	0.1	0.8	-0.8	-0.4
Commuting to job workplace: Public transport	0.2	0.3	1.0	0.0	-0.3	0.0	0.5	-0.5	0.8	1.0	-0.0
High cholesterol (Self-reported)	0.2	0.4	0.5	0.4	-0.7	0.7	0.4	0.7	-0.6	-0.7	-0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	-0.1	-0.7	0.2	0.3	-0.9	-0.3	-0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.4	0.0	0.2	0.3	-0.8	-0.2	-0.2	0.8
Impedance of whole body	0.2	0.8	4.2	0.1	-0.7	0.4	2.1	-0.7	0.9	-0.5	-0.3
Bipolar Disorder (2018)	0.1	0.2	1.3	0.0	0.3	-0.3	-1.1	-0.2	0.3	0.1	0.1
Bipolar Disorder or Schizophrenia	0.1	0.3	0.6	0.4	-0.6	0.7	0.1	0.8	0.7	-0.4	-0.5
Depression (Nagel 2018)	0.1	0.1	0.3	-0.1	0.2	0.1	-0.3	-0.2	0.5	0.5	0.0
Breast Cancer	0.1	0.3	0.7	0.6	0.0	0.6	-0.4	-0.7	0.6	-0.9	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.4	-0.3	0.1	0.1	0.2	-0.6	-0.1	-0.3	0.3
Neuroticism (2016)	0.1	0.2	0.6	0.4	0.3	0.8	0.4	-0.3	0.4	0.0	-0.2
Ulcerative Colitis	0.1	0.2	0.6	0.7	0.3	0.7	0.2	-0.2	0.8	-0.3	-0.0
Heel T-Score	0.1	0.7	2.8	0.3	0.9	-0.6	-0.7	-1.7	-0.2	0.8	-0.3
Smoking Status	0.1	0.2	0.8	-0.0	0.9	0.1	-0.0	0.7	0.1	0.5	0.2
Lung FVC	0.1	0.3	0.8	-0.5	-0.9	-0.7	-0.3	-0.7	-0.5	0.1	-0.1
Hair Pigment	0.1	1.6	2.6	1.6	-1.0	1.1	0.7	1.3	1.3	-1.5	-1.2
Number of treatments/medications taken	0.1	0.2	1.1	0.3	-0.0	0.2	0.5	1.1	-0.1	-0.4	-0.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.4	0.1	-0.3	0.5	0.6	-0.5	0.6	0.2	-0.2
Systolic blood pressure, automated reading	0.1	0.3	1.1	0.5	-0.1	0.1	-0.1	1.0	-0.7	-0.6	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.9	-0.2	0.3	-0.1	-0.0	-1.0	0.1	0.6	-0.0
Stomach or abdominal pain in last month	0.1	0.1	0.4	-0.1	0.0	0.1	0.4	-0.3	0.1	0.6	-0.1
High blood pressure (mother)	0.1	0.1	0.3	0.0	0.5	0.0	-0.4	0.1	-0.3	-0.5	0.0
Heart attack	0.1	0.2	0.8	-0.3	-0.4	-0.1	0.1	-0.9	-0.4	0.1	0.1
Neuroticism score	0.1	0.3	0.8	-0.0	0.9	0.2	0.7	-0.0	0.7	0.4	0.3
Mouth/teeth dental problems: Dentures	0.1	0.1	0.3	-0.2	0.6	-0.1	-0.1	0.4	-0.3	0.5	0.1
Medication: Cholesterol lowering	0.1	0.2	0.8	0.0	-0.3	0.2	0.3	0.5	-0.9	-0.4	0.1
Blood clot in the leg (DVT)	0.1	0.1	0.5	-0.3	-0.1	0.2	0.3	-0.4	0.0	-0.4	0.7
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.3	-0.3	-0.1	-0.4	-0.0	0.1	-0.5	-0.5	-0.0
Medication for pain relief, constipation, heartburn	0.1	0.2	1.1	-0.3	0.4	-0.0	0.0	-1.1	0.4	0.3	0.4
Pulse rate, automated reading	0.1	0.5	2.0	-0.5	-0.3	-1.1	-0.4	-0.0	-1.4	0.1	-0.1
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.3	-0.2	-0.3	-0.4	0.6	-0.1	-0.4	0.3	0.0
Smoking status: Current	0.1	0.1	0.6	-0.1	0.7	0.1	-0.4	-0.1	0.5	0.2	0.2
Financial situation satisfaction	0.1	0.2	0.4	-0.6	0.3	-0.4	-0.6	-0.1	0.0	-0.1	0.5
Average weekly beer plus cider intake	0.1	0.1	0.5	0.5	0.2	0.5	-0.1	0.2	0.7	-0.0	-0.2
Pain experienced in last month	0.1	0.2	0.7	0.3	-0.3	0.6	0.0	-0.9	0.5	-0.3	-0.1
Lung FEV1/FVC ratio	0.0	0.2	1.1	0.1	-0.2	-0.3	1.1	0.5	0.2	-0.4	-0.2

Hub : Genes

RSBN1L

Models

Trait associations