[Hub]/) : Traits : Leg fat mass (left) : ← →

chr1:31,494,475-34,592,020

Best TWAS P=1.05e-10 · Best GWAS P=1.73e-12 conditioned to 0.0125

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Thyroid	BAI2	0.31	0.23	lasso	6	0.22	1.4e-16	6.4	6.5	1.0e-10	0.81	0.20	0.80	TRUE
3	CommonMind	Brain Pre-frontal Cortex	TMEM54	0.05	0.00	blup	281	0.02	4.5e-03	0.8	-6.5	1.1e-10	-0.03	0.10	0.30	TRUE
1	CommonMind	Brain Pre-frontal Cortex	HPCA	0.11	0.09	bslmm	279	0.10	1.0e-11	-5.2	5.2	2.5e-07	0.03	0.46	0.54	TRUE
12	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	S100PBP	0.06	0.03	blup	48	0.06	6.8e-04	-6.1	6.4	1.4e-10	0.00	0.01	0.81	FALSE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	S100PBP	0.06	0.06	blup	47	0.05	5.2e-06	-6.2	6.2	4.6e-10	0.02	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	S100PBP	0.04	0.04	lasso	4	0.04	2.3e-05	-6.2	6.2	5.1e-10	-0.01	0.01	0.99	FALSE
6	GTEx	Muscle Skeletal	FNDC5	0.15	0.16	enet	5	0.16	1.9e-15	-6.0	-6.0	2.4e-09	0.01	0.03	0.97	FALSE
13	The Cancer Genome Atlas	Glioblastoma Multiforme	S100PBP	0.21	0.15	lasso	5	0.15	2.9e-05	-6.0	6.0	2.6e-09	-0.01	0.01	0.92	FALSE
11	The Cancer Genome Atlas	Breast Invasive Carcinoma	S100PBP	0.03	0.02	blup	46	0.02	6.6e-06	-6.2	5.9	4.8e-09	-0.02	0.01	0.99	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	PHC2	0.58	0.34	lasso	7	0.28	7.3e-10	-5.6	5.6	1.7e-08	0.04	0.11	0.89	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FNDC5	0.03	0.04	enet	6	0.03	2.9e-04	-6.1	-5.6	2.1e-08	0.03	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Lung Adenocarcinoma	COL16A1	0.04	0.03	lasso	4	0.03	5.2e-04	6.5	-5.5	3.2e-08	-0.82	0.03	0.79	FALSE
4	CommonMind	Brain Pre-frontal Cortex	ZNF362	0.05	0.06	lasso	1	0.06	2.2e-07	-5.5	-5.5	4.2e-08	-0.04	0.36	0.64	FALSE
2	CommonMind	Brain Pre-frontal Cortex	S100PBP	0.05	0.04	enet	10	0.02	1.2e-03	-6.3	5.4	5.1e-08	-0.01	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	FNDC5	0.02	0.01	blup	33	0.01	9.2e-03	-4.3	-5.2	1.6e-07	-0.01	0.01	0.53	FALSE
8	GTEx	Thyroid	TMEM54	0.10	0.09	lasso	7	0.07	3.3e-06	-5.2	5.2	1.7e-07	-0.01	0.42	0.58	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	PHC2	0.11	0.07	lasso	3	0.05	2.2e-07	-5.6	-5.2	1.7e-07	-0.03	0.13	0.87	FALSE