[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr16:88,013,385-90,172,696

Best TWAS P=1.28e-13 · Best GWAS P=3.31e-12 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Colon Transverse	RPL13	0.23	0.17	lasso	4	0.16	3.7e-08	6.7	-7.4	1.3e-13	-0.06	0.01	0.99	TRUE
22	GTEx	Whole Blood	CTD-2555A7.3	0.10	0.00	lasso	5	0.01	1.0e-01	4.2	7.0	2.0e-12	-0.39	0.04	0.73	TRUE
7	GTEx	Cells Transformed fibroblasts	RPL13	0.10	0.08	enet	8	0.09	3.7e-07	5.8	-6.9	5.9e-12	-0.01	0.03	0.97	TRUE
38	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPL13	0.04	0.03	blup	41	0.03	2.2e-03	6.1	-6.8	1.2e-11	-0.03	0.02	0.87	TRUE
18	GTEx	Testis	RPL13	0.25	0.22	lasso	5	0.21	1.6e-09	6.1	-6.4	1.8e-10	-0.04	0.03	0.97	TRUE
6	GTEx	Cells EBV-transformed lymphocytes	CTD-2555A7.3	0.20	0.16	lasso	5	0.15	1.2e-05	4.2	5.6	1.9e-08	-0.01	0.64	0.12	TRUE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	SPG7	0.03	0.03	lasso	4	0.02	8.0e-06	4.6	-5.3	9.8e-08	0.00	0.06	0.94	TRUE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SNAI3	0.05	0.02	lasso	5	0.01	1.0e-02	-3.3	-5.2	2.0e-07	0.47	0.04	0.48	TRUE
19	GTEx	Thyroid	RPL13	0.13	0.05	enet	10	0.06	1.4e-05	6.6	-6.8	9.3e-12	-0.08	0.02	0.98	FALSE
10	GTEx	Esophagus Muscularis	RPL13	0.17	0.12	lasso	3	0.11	2.4e-07	6.7	-6.8	1.1e-11	-0.04	0.01	0.99	FALSE
21	GTEx	Whole Blood	SPG7	0.06	0.05	lasso	3	0.05	3.9e-05	6.5	-6.7	1.9e-11	-0.08	0.03	0.95	FALSE
2	GTEx	Artery Aorta	RPL13	0.19	0.20	lasso	5	0.17	1.7e-09	6.1	-6.6	3.8e-11	-0.05	0.02	0.98	FALSE
17	GTEx	Skin Sun Exposed Lower leg	SPG7	0.09	0.05	lasso	2	0.03	1.5e-03	6.7	-6.6	5.3e-11	-0.03	0.02	0.98	FALSE
15	GTEx	Skin Not Sun Exposed Suprapubic	RPL13	0.16	0.15	lasso	4	0.15	2.0e-08	6.5	-6.6	5.6e-11	-0.02	0.02	0.98	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPG7	0.03	0.02	blup	58	0.03	4.1e-04	5.8	-6.5	6.0e-11	-0.08	0.02	0.74	FALSE
29	The Cancer Genome Atlas	Esophageal Carcinoma	RPL13	0.14	0.07	lasso	3	0.04	2.6e-02	6.4	-6.5	8.1e-11	-0.04	0.01	0.84	FALSE
37	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPG7	0.11	0.09	lasso	2	0.08	2.5e-04	6.5	-6.5	8.1e-11	-0.03	0.02	0.95	FALSE
36	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPL13	0.03	0.01	blup	41	0.02	8.5e-03	6.1	-6.5	8.2e-11	-0.06	0.01	0.76	FALSE
23	METSIM	Adipose	RPL13	0.05	0.05	enet	5	0.05	1.0e-07	6.6	-6.4	1.3e-10	-0.04	0.02	0.98	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SPG7	0.05	0.05	lasso	5	0.05	1.9e-06	6.4	-6.4	1.3e-10	-0.03	0.02	0.98	FALSE
30	The Cancer Genome Atlas	Glioblastoma Multiforme	SNAI3	0.19	0.06	enet	7	0.12	1.6e-04	3.2	-6.4	1.8e-10	0.70	0.00	0.86	FALSE
12	GTEx	Muscle Skeletal	RPL13	0.10	0.09	lasso	5	0.10	3.3e-10	6.1	-6.4	1.9e-10	-0.03	0.03	0.97	FALSE
26	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SPG7	0.05	0.03	lasso	3	0.03	1.8e-03	6.4	-6.4	2.0e-10	-0.03	0.01	0.91	FALSE
4	GTEx	Breast Mammary Tissue	RPL13	0.09	0.05	enet	7	0.04	5.3e-03	6.9	-6.2	5.3e-10	-0.07	0.02	0.94	FALSE
14	GTEx	Nerve Tibial	RPL13	0.10	0.07	lasso	3	0.07	2.0e-05	6.5	-6.2	7.2e-10	-0.02	0.02	0.98	FALSE
8	GTEx	Colon Sigmoid	RPL13	0.17	0.18	lasso	1	0.16	3.1e-06	6.1	-6.1	1.0e-09	-0.04	0.02	0.98	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	MGC23284	0.09	0.04	enet	19	0.03	1.7e-04	-4.9	-6.0	1.7e-09	0.62	0.09	0.86	FALSE
24	NTR	Blood	RPL13	0.02	0.01	bslmm	365	0.01	5.9e-05	6.7	6.0	2.2e-09	-0.01	0.02	0.98	FALSE
39	The Cancer Genome Atlas	Thyroid Carcinoma	SPG7	0.10	0.09	lasso	4	0.11	1.9e-10	6.5	-5.9	3.6e-09	0.05	0.01	0.99	FALSE
13	GTEx	Muscle Skeletal	SPG7	0.24	0.22	lasso	5	0.23	8.9e-23	-4.1	-5.7	1.6e-08	-0.16	1.00	0.00	FALSE
16	GTEx	Skin Sun Exposed Lower leg	RPL13	0.11	0.13	enet	7	0.12	1.7e-10	5.6	-5.6	1.7e-08	-0.03	0.07	0.93	FALSE
1	GTEx	Adipose Visceral Omentum	RPL13	0.19	0.03	lasso	2	0.06	3.0e-04	5.6	-5.6	2.1e-08	0.00	0.04	0.86	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAI3	0.05	0.06	lasso	3	0.04	7.0e-06	-4.9	-5.6	2.7e-08	0.58	0.22	0.74	FALSE
20	GTEx	Whole Blood	ACSF3	0.14	0.04	lasso	3	0.03	3.8e-04	4.5	5.5	4.7e-08	-0.15	0.63	0.23	FALSE
3	GTEx	Brain Putamen basal ganglia	CYBA	0.53	0.01	enet	54	0.08	5.9e-03	-1.4	5.4	6.1e-08	-0.16	0.04	0.12	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	ACSF3	0.32	0.33	enet	11	0.37	5.7e-13	4.3	5.4	7.0e-08	-0.03	1.00	0.00	FALSE
25	NTR	Blood	SNAI3	0.05	0.04	bslmm	374	0.04	5.0e-13	-4.9	-5.3	8.6e-08	0.53	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	SPG7	0.13	0.01	blup	59	0.03	5.8e-03	-2.7	-5.3	1.0e-07	0.05	0.01	0.35	FALSE
11	GTEx	Lung	RP5-1142A6.5	0.15	0.08	lasso	3	0.09	4.0e-07	-6.0	-5.2	2.5e-07	0.42	0.59	0.38	FALSE