[Hub]/) : Traits : Leg fat-free mass (left) : ← →

chr2:231,913,056-234,123,010

Best TWAS P=1.74e-12 · Best GWAS P=6.53e-10 conditioned to 0.00267

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Liver PDE6D 0.21 0.10 lasso 4 0.09 1.8e-03 -5.4 -5.8 5.0e-09 -0.06 0.02 0.81 TRUE
2 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C2orf52 0.28 0.12 lasso 6 0.12 2.0e-06 -5.4 5.4 6.2e-08 0.04 0.00 0.99 FALSE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EFHD1 0.11 0.01 blup 70 0.03 1.0e-02 5.6 7.0 1.7e-12 -0.61 0.01 0.85 TRUE
4 The Cancer Genome Atlas Brain Lower Grade Glioma GIGYF2 0.02 0.01 lasso 3 0.01 5.3e-02 -5.7 -5.7 9.7e-09 0.91 0.04 0.83 FALSE
5 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C2orf52 0.28 0.18 lasso 4 0.20 3.7e-22 -5.4 5.2 2.3e-07 0.04 0.00 1.00 FALSE
6 The Cancer Genome Atlas Pancreatic Adenocarcinoma KCNJ13 0.07 0.07 blup 36 0.06 2.4e-03 -5.8 5.2 1.6e-07 -0.86 0.01 0.84 FALSE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C2orf52 0.27 0.27 lasso 5 0.28 1.7e-11 -5.2 5.1 2.7e-07 0.02 0.01 0.99 FALSE
8 The Cancer Genome Atlas Skin Cutaneous Melanoma C2orf52 0.21 0.20 lasso 1 0.18 1.4e-05 -5.4 5.4 8.4e-08 0.03 0.00 0.95 TRUE
9 The Cancer Genome Atlas Testicular Germ Cell Tumors C2orf52 0.29 0.17 enet 10 0.19 3.2e-07 -5.2 5.2 1.9e-07 0.03 0.01 0.99 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma KCNJ13 0.03 0.00 blup 35 0.01 4.3e-02 5.7 -6.7 1.8e-11 0.86 0.01 0.55 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma NGEF 0.04 0.03 enet 7 0.03 5.6e-04 5.7 -6.5 7.1e-11 0.76 0.01 0.98 FALSE