TWAS hub - C2orf52

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.145	0.0550	1.0e-10	0.141	0.125	0.131	NA	0.119	5.3e-12	9.7e-11	3.7e-11	NA	3.2e-10
2	TCGA	Breast Invasive Carcinoma	0.188	0.0506	0.0e+00	0.217	0.247	0.245	NA	0.239	2.1e-43	4.1e-50	1.3e-49	NA	3.3e-48
3	TCGA	Cervical Squamous Cell Carcinoma	0.276	0.1000	5.3e-08	0.117	0.108	0.111	NA	0.118	2.3e-06	5.5e-06	4.4e-06	NA	2.0e-06
4	TCGA	Colon Adenocarcinoma	0.209	0.0670	5.2e-14	0.165	0.237	0.236	NA	0.218	7.8e-10	7.1e-14	8.0e-14	NA	8.6e-13
5	TCGA	Esophageal Carcinoma	0.156	0.0720	3.5e-04	0.026	0.086	0.105	NA	0.083	5.0e-02	1.1e-03	3.3e-04	NA	1.3e-03
6	TCGA	Glioblastoma Multiforme	0.283	0.0970	3.5e-06	0.125	0.168	0.176	NA	0.149	1.3e-04	8.2e-06	5.0e-06	NA	2.8e-05
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.184	0.0590	0.0e+00	0.160	0.170	0.167	NA	0.159	1.4e-17	9.8e-19	2.5e-18	NA	1.7e-17
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.229	0.0567	0.0e+00	0.248	0.280	0.285	NA	0.279	1.2e-27	1.4e-31	2.9e-32	NA	1.6e-31
9	TCGA	Kidney Renal Papillary Cell Carcinoma	0.180	0.0660	1.6e-08	0.200	0.156	0.171	NA	0.192	1.2e-11	2.8e-09	4.9e-10	NA	3.4e-11
10	TCGA	Brain Lower Grade Glioma	0.316	0.0743	0.0e+00	0.254	0.308	0.299	NA	0.291	1.2e-28	1.5e-35	2.4e-34	NA	3.0e-33
11	TCGA	Liver Hepatocellular Carcinoma	0.131	0.0740	6.0e-03	0.065	0.045	0.026	NA	0.050	5.6e-04	3.4e-03	2.2e-02	NA	2.1e-03
12	TCGA	Lung Adenocarcinoma	0.182	0.0508	0.0e+00	0.164	0.176	0.186	NA	0.177	1.1e-18	4.6e-20	3.0e-21	NA	3.2e-20
13	TCGA	Lung Squamous Cell Carcinoma	0.275	0.0724	0.0e+00	0.185	0.191	0.189	NA	0.199	1.5e-20	3.4e-21	5.6e-21	NA	3.7e-22
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.236	0.0810	7.1e-12	0.197	0.187	0.190	NA	0.200	2.2e-13	1.0e-12	6.1e-13	NA	1.4e-13
15	TCGA	Pancreatic Adenocarcinoma	0.324	0.1030	1.5e-09	0.209	0.190	0.196	NA	0.209	3.6e-09	2.1e-08	1.2e-08	NA	3.6e-09
16	TCGA	Pheochromocytoma and Paraganglioma	0.267	0.0930	1.7e-09	0.266	0.267	0.268	NA	0.277	5.1e-11	4.6e-11	3.9e-11	NA	1.7e-11
17	TCGA	Prostate Adenocarcinoma	0.321	0.0700	0.0e+00	0.338	0.394	0.393	NA	0.392	2.4e-36	9.3e-44	1.2e-43	NA	1.7e-43
18	TCGA	Soft Tissue Sarcoma	0.334	0.0830	3.9e-11	0.165	0.207	0.199	NA	0.170	4.7e-10	2.0e-12	5.9e-12	NA	2.5e-10
19	TCGA	Skin Cutaneous Melanoma	0.205	0.1130	3.0e-03	0.201	0.076	0.131	NA	0.181	4.5e-06	4.5e-03	2.3e-04	NA	1.4e-05
20	TCGA	Stomach Adenocarcinoma	0.119	0.0470	6.1e-08	0.097	0.111	0.120	NA	0.115	1.6e-07	2.2e-08	5.6e-09	NA	1.1e-08
21	TCGA	Testicular Germ Cell Tumors	0.288	0.1070	9.0e-06	0.171	0.181	0.188	NA	0.181	1.2e-06	5.5e-07	3.2e-07	NA	5.8e-07
22	TCGA	Thyroid Carcinoma	0.450	0.1010	0.0e+00	0.307	0.323	0.348	NA	0.337	2.5e-30	3.8e-32	4.9e-35	NA	9.7e-34

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Forced vital capacity (FVC)	8.5	32.8	39.9	5.9	5.8	5.5	6.3	5.6	6.2	6.0	6.2	5.3	6.0	5.4	6.3	5.4	5.3	5.4	5.8	6.0	5.5	5.2	5.7	5.2	5.9
Stomach or abdominal pain in last month	7.9	9.8	14.8	-3.2	-3.2	-2.6	-2.9	-2.7	-2.5	-3.3	-3.3	-3.2	-3.6	-3.3	-3.9	-3.1	-3.2	-3.2	-3.1	-3.1	-3.2	-3.0	-2.8	-3.1	-3.2
Height	7.4	142.6	207.4	12.5	10.4	14.4	13.5	10.3	13.5	11.2	12.2	12.6	9.1	12.4	10.4	12.5	12.5	11.8	12.9	11.7	8.0	13.0	13.3	11.7	10.8
Sitting height	7.2	50.9	67.4	7.7	6.8	7.7	8.2	7.0	7.9	6.7	7.4	7.1	6.8	7.1	6.7	6.8	7.0	6.8	7.8	7.5	5.4	7.0	7.6	6.3	6.7
Forced vital capacity (FVC), Best measure	7.1	25.9	34.5	5.4	5.1	5.5	5.9	4.9	5.9	5.2	5.5	4.7	5.1	4.8	5.3	4.8	4.6	4.9	5.3	5.5	4.3	4.5	5.2	4.4	5.0
Trunk fat-free mass	6.6	37.6	49.3	6.5	5.5	7.0	6.6	5.4	6.8	5.4	6.1	6.4	5.3	6.4	5.7	6.5	6.3	6.1	6.6	5.9	5.0	6.8	6.2	6.3	5.6
Trunk predicted mass	6.6	37.5	49.6	6.5	5.5	7.0	6.6	5.4	6.8	5.4	6.1	6.3	5.2	6.4	5.7	6.5	6.3	6.1	6.6	5.9	5.0	6.8	6.2	6.3	5.5
Standing height	6.6	65.4	93.9	8.5	7.2	9.7	9.1	6.9	9.4	7.5	8.3	8.4	6.4	8.4	7.4	8.5	8.3	8.0	8.6	7.9	5.6	8.7	8.7	7.8	7.3
Ever highly irritable/argumentative for 2 days	6.4	7.7	10.4	-2.8	-3.1	-2.4	-3.0	-2.6	-3.0	-3.2	-3.1	-2.4	-3.0	-2.4	-2.8	-2.7	-2.3	-2.8	-2.6	-3.1	-2.6	-2.3	-3.0	-2.4	-2.9
Whole body fat-free mass	5.7	32.4	42.1	6.0	5.1	6.5	6.1	5.0	6.2	5.0	5.7	5.9	4.9	6.0	5.4	6.1	5.8	5.8	6.1	5.4	4.7	6.4	5.7	5.9	5.1
Whole body water mass	5.7	32.4	42.0	6.0	5.2	6.5	6.0	5.0	6.1	5.0	5.7	5.9	5.0	6.0	5.4	6.1	5.8	5.8	6.1	5.4	4.8	6.4	5.6	6.0	5.2
Arm predicted mass (right)	5.3	27.1	36.2	5.4	4.7	6.0	5.4	4.6	5.7	4.8	5.2	5.2	4.6	5.3	5.0	5.6	5.2	5.3	5.4	5.0	4.6	5.8	5.1	5.6	4.7
Forced expiratory volume in 1-second (FEV1)	5.2	17.7	23.0	4.3	4.2	3.9	4.8	4.0	4.6	4.3	4.5	4.0	4.5	4.1	4.8	3.9	4.0	4.0	4.3	4.3	3.8	3.9	4.0	3.7	4.3
Arm fat-free mass (right)	4.9	25.2	34.2	5.2	4.6	5.8	5.3	4.5	5.6	4.5	5.1	5.0	4.4	5.1	4.6	5.4	5.0	5.1	5.2	4.8	4.3	5.6	5.0	5.3	4.6
Leg pain on walking	4.9	6.1	8.2	-2.6	-2.4	-1.9	-2.4	-2.4	-1.7	-2.5	-2.6	-2.9	-2.3	-2.8	-2.7	-2.3	-2.8	-2.1	-2.8	-2.4	-2.3	-2.4	-2.6	-2.2	-2.9
Forced expiratory volume in 1-second (FEV1), Best measure	4.7	15.1	19.8	4.1	3.9	4.0	4.5	3.5	4.3	3.9	4.1	3.8	4.0	3.9	4.2	3.6	3.8	3.8	4.1	4.0	3.2	3.6	3.8	3.3	3.9
Leg fat-free mass (right)	4.6	24.3	31.4	5.3	4.5	5.6	5.2	4.2	5.3	4.4	4.9	5.1	4.2	5.2	4.8	5.3	5.0	5.1	5.3	4.6	4.0	5.5	4.8	5.2	4.5
Leg predicted mass (right)	4.6	24.5	31.6	5.3	4.5	5.6	5.2	4.2	5.3	4.4	4.9	5.1	4.2	5.3	4.8	5.3	5.1	5.1	5.4	4.6	4.0	5.5	4.8	5.2	4.5
Basal metabolic rate	4.6	25.4	33.2	5.3	4.6	5.8	5.3	4.4	5.4	4.4	5.0	5.2	4.4	5.3	4.8	5.5	5.1	5.1	5.4	4.8	4.3	5.7	4.9	5.3	4.6
Leg predicted mass (left)	4.5	23.9	30.5	5.2	4.4	5.5	5.1	4.2	5.2	4.3	4.9	5.0	4.2	5.2	4.9	5.3	5.0	5.0	5.2	4.6	4.2	5.5	4.7	5.3	4.4
Fractured/broken bones in last 5 years	4.5	5.8	11.1	2.5	2.0	2.7	3.2	2.5	3.3	2.5	2.4	2.2	1.2	2.2	1.8	2.2	2.1	1.9	2.8	2.5	1.4	2.1	3.3	2.6	2.1
Leg fat-free mass (left)	4.3	22.8	29.3	5.0	4.3	5.4	5.0	4.1	5.1	4.2	4.8	4.9	4.1	5.0	4.8	5.2	4.9	4.9	5.1	4.5	4.1	5.4	4.6	5.2	4.3
Arm fat-free mass (left)	4.2	21.5	29.8	4.8	4.2	5.5	4.7	4.1	4.8	4.0	4.6	4.8	4.0	4.8	4.3	5.1	4.7	4.7	4.9	4.3	4.1	5.4	4.5	4.9	4.2
Number of full brothers	4.1	5.2	11.7	2.3	2.1	3.4	3.0	2.8	3.1	2.4	2.5	1.7	1.4	1.6	1.6	2.1	1.6	2.1	2.3	2.6	1.4	1.6	2.9	2.0	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.1	4.8	6.2	-2.3	-2.1	-1.6	-1.9	-1.7	-1.8	-2.4	-2.3	-2.4	-2.5	-2.5	-2.4	-2.1	-2.4	-2.3	-2.3	-1.9	-2.4	-2.0	-2.0	-2.3	-2.2
Arm predicted mass (left)	4.0	20.1	29.6	4.7	3.9	5.4	4.6	3.9	4.8	3.8	4.4	4.6	3.8	4.7	4.0	5.0	4.6	4.6	4.8	4.2	3.8	5.3	4.4	4.8	4.0
Gout (self-reported)	3.7	5.1	6.7	-2.3	-2.6	-1.9	-2.2	-2.1	-1.9	-2.3	-2.3	-2.3	-2.5	-2.3	-2.5	-2.5	-2.3	-2.4	-2.1	-2.2	-2.2	-2.6	-2.0	-1.6	-2.4
Eye problems/disorders: None of the above	3.7	4.2	5.4	2.2	2.0	2.2	2.2	1.7	2.2	2.3	2.0	2.1	2.1	2.1	1.8	2.0	2.1	2.1	2.2	2.1	1.7	2.0	2.0	1.9	1.9
Forced expiratory volume in 1-second (FEV1), predicted	3.7	7.7	12.7	2.8	2.7	3.6	3.1	3.2	3.3	2.5	2.9	2.4	2.9	2.3	2.5	2.9	2.3	2.7	2.8	2.9	2.2	2.6	2.9	2.2	2.6
Commuting to job workplace: Walk	3.7	4.0	8.1	1.9	2.1	2.1	2.5	2.1	2.8	2.1	2.2	1.8	1.7	1.6	1.8	1.9	1.7	1.8	1.9	2.3	1.6	1.7	2.4	1.8	2.0
Medication: Allopurinol	3.6	4.8	7.7	-2.2	-2.4	-1.4	-1.9	-1.8	-1.4	-2.3	-2.2	-2.3	-2.6	-2.4	-2.8	-2.4	-2.3	-2.2	-2.0	-2.1	-2.5	-2.6	-1.9	-1.4	-2.3
Supplements: Zinc	3.5	3.8	6.7	-2.1	-2.1	-1.8	-2.5	-2.5	-2.6	-1.7	-1.9	-1.8	-2.2	-1.6	-1.7	-1.6	-1.8	-1.6	-2.0	-2.3	-1.5	-1.8	-2.2	-0.9	-1.9
Primary Biliary Cirrhosis	3.4	4.9	6.7	-2.3	-2.4	-1.5	-2.4	-2.1	-2.4	-2.6	-2.3	-2.0	-2.3	-2.1	-2.5	-1.9	-2.0	-2.1	-2.2	-2.4	-2.4	-1.8	-2.3	-1.8	-2.3
Tinnitus: Yes, now most or all of the time	3.3	3.9	5.1	2.0	2.1	1.5	2.2	2.3	1.9	2.3	2.0	1.9	1.9	1.8	2.1	1.7	1.8	1.8	2.0	2.1	2.2	1.9	2.0	1.6	1.9
Unable to work because of sickness or disability	3.3	4.3	6.8	-2.3	-1.9	-0.9	-2.1	-1.8	-1.0	-2.0	-2.0	-2.6	-2.4	-2.6	-2.5	-1.7	-2.6	-1.7	-2.4	-2.0	-1.8	-2.3	-2.0	-1.6	-2.2
Ovarian Cancer	3.1	4.1	7.4	2.2	1.8	1.9	2.3	2.3	1.7	2.3	2.0	2.1	1.0	2.1	1.8	1.8	2.0	1.6	2.4	2.3	1.7	1.8	2.7	1.9	2.3
Loneliness, isolation	3.1	4.3	7.6	-2.1	-2.2	-1.1	-1.8	-1.4	-1.5	-2.5	-1.9	-2.2	-2.2	-2.3	-2.8	-1.8	-2.3	-2.2	-1.9	-2.1	-2.5	-2.1	-1.6	-2.2	-2.1
Ever smoked	3.1	5.5	7.3	2.7	2.5	2.1	2.7	1.8	2.4	2.5	2.2	2.7	1.8	2.6	2.3	2.0	2.7	2.5	2.6	2.5	1.8	2.3	2.4	1.8	2.4
Verbal and Numeric Reasoning (VNR)	3.0	7.3	12.8	3.2	2.3	1.9	2.9	2.4	2.1	2.9	2.3	3.5	2.4	3.4	2.4	2.2	3.4	2.3	3.6	2.5	1.6	3.1	3.0	2.3	2.4
Leg fat percentage (left)	2.7	9.9	17.9	-3.5	-2.9	-3.3	-4.2	-3.0	-4.2	-3.2	-3.1	-3.2	-2.4	-3.1	-2.7	-2.5	-3.2	-2.7	-3.7	-3.4	-1.7	-2.8	-3.8	-2.5	-2.8
Hearing difficulty/problems: Yes	2.6	3.9	5.8	-2.0	-1.9	-2.0	-2.3	-1.3	-2.4	-2.2	-1.9	-2.2	-1.2	-2.2	-2.1	-2.1	-2.2	-2.0	-1.9	-1.8	-1.4	-2.4	-1.9	-1.9	-1.9
Time employed in main current job	2.6	3.1	5.4	-2.0	-1.9	-1.5	-2.0	-2.0	-1.7	-1.5	-1.8	-1.8	-2.3	-1.7	-1.7	-1.5	-1.8	-1.5	-2.0	-1.9	-0.9	-1.6	-1.8	-1.0	-1.7
Schizophrenia (2014)	2.5	5.5	8.5	-2.5	-2.7	-2.0	-2.6	-2.7	-2.1	-2.4	-2.3	-2.3	-2.9	-2.2	-2.4	-2.0	-2.3	-2.4	-2.3	-2.6	-2.1	-2.2	-2.2	-1.0	-2.6
Type 2 Diabetes (T2D) (2012)	2.5	2.9	5.1	-1.7	-1.4	-1.9	-1.6	-1.7	-1.6	-1.8	-1.8	-1.6	-1.7	-1.5	-1.6	-1.7	-1.6	-1.5	-1.7	-1.7	-1.6	-1.6	-1.8	-2.2	-1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.5	5.3	8.5	2.3	2.6	1.9	2.5	2.5	2.4	2.9	2.5	1.7	2.7	1.8	2.6	1.9	1.7	2.3	2.1	2.6	2.5	1.5	2.3	2.0	2.6
Hair/balding pattern: Pattern 4	2.4	5.8	8.4	2.6	2.3	2.7	2.9	2.6	2.6	2.6	2.3	2.4	1.9	2.2	1.9	2.1	2.4	2.1	2.6	2.8	1.7	2.4	2.9	2.0	2.1
Peak expiratory flow (PEF)	2.4	5.5	9.0	2.5	2.2	1.9	3.0	2.4	2.9	2.3	2.4	2.2	2.4	2.3	2.6	1.8	2.2	1.9	2.7	2.5	1.8	2.1	2.5	1.9	2.2
Leg fat percentage (right)	2.4	8.7	16.2	-3.3	-2.8	-3.1	-4.0	-2.7	-3.9	-3.0	-2.9	-3.1	-2.2	-3.0	-2.5	-2.4	-3.0	-2.6	-3.5	-3.2	-1.4	-2.6	-3.5	-2.1	-2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	4.5	1.9	1.6	0.8	1.9	1.3	1.6	1.7	1.5	2.1	1.6	2.1	2.1	1.3	2.1	1.4	2.1	1.8	1.3	1.8	1.8	1.5	1.4
Commuting to job workplace: Cycle	2.4	2.9	6.4	1.7	2.2	1.8	2.1	2.1	2.5	2.0	1.9	1.2	1.6	1.1	1.4	1.4	1.1	1.8	1.5	2.1	1.1	0.9	1.7	1.4	2.0
Fluid intelligence score	2.3	4.8	9.5	2.6	1.6	1.4	2.2	1.4	1.4	2.3	1.9	3.1	1.9	3.1	2.1	1.9	3.1	1.9	3.0	1.7	1.1	2.6	2.5	2.0	1.9
Birth weight of first child	2.3	4.1	13.2	1.9	2.0	2.3	2.7	1.5	3.6	2.3	2.2	1.6	1.2	1.6	1.9	1.7	1.5	2.2	1.8	2.0	1.6	1.3	2.2	2.3	1.8
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.6	3.8	-1.8	-1.7	-1.9	-1.8	-1.2	-1.9	-1.1	-1.4	-1.8	-1.3	-1.9	-1.3	-1.7	-1.8	-1.9	-1.9	-1.4	-0.4	-2.0	-1.3	-1.1	-1.4
Medication for cholesterol, blood pressure or diabetes	2.2	3.7	6.0	1.9	1.9	1.7	2.1	1.6	2.4	1.7	2.0	1.9	1.5	1.9	1.9	1.8	1.9	1.8	2.0	2.0	1.9	1.7	2.1	2.1	1.9
Supplements: Fish oil (including cod liver oil)	2.2	2.8	3.7	1.6	1.5	1.4	1.7	1.3	1.8	1.8	1.8	1.6	1.5	1.7	1.8	1.9	1.6	1.8	1.4	1.5	1.9	1.9	1.7	1.9	1.6
Pain experienced in last month	2.2	3.7	6.2	1.9	1.9	1.2	1.2	0.7	1.4	2.1	1.9	2.3	2.2	2.4	2.5	2.0	2.3	2.1	2.0	1.3	2.1	2.0	1.0	2.4	2.0
Qualifications: CSEs or equivalent	2.1	2.7	4.1	1.7	1.4	2.0	1.8	1.3	1.7	1.1	1.7	1.9	1.2	1.8	1.5	1.9	1.9	1.8	1.7	1.4	1.4	2.0	1.7	1.7	1.4
Had menopause	2.1	2.6	4.3	-1.7	-1.8	-1.6	-1.8	-1.5	-2.1	-1.6	-1.6	-1.4	-1.7	-1.4	-1.8	-1.2	-1.4	-1.5	-1.7	-1.8	-2.0	-1.1	-1.3	-1.5	-1.6
Pulse wave reflection index	2.1	2.6	3.8	-1.7	-1.2	-1.8	-1.4	-1.0	-1.7	-0.8	-1.6	-1.9	-1.5	-1.8	-1.4	-1.8	-1.9	-1.8	-1.7	-1.3	-1.8	-1.8	-1.6	-1.9	-1.2
Qualifications: College or University degree	2.1	6.5	10.7	2.8	2.3	2.4	2.9	2.4	3.1	2.6	2.4	2.6	2.0	2.7	2.1	2.3	2.5	2.0	3.3	2.7	2.1	2.6	2.9	2.9	2.3
Age at last live birth	2.1	3.1	5.3	2.1	1.7	1.6	1.8	1.4	1.7	1.4	1.7	2.1	1.6	2.1	1.7	1.7	2.1	1.7	2.3	1.6	1.2	1.9	1.5	1.8	1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.5	3.8	1.5	1.7	1.4	1.6	1.3	1.9	1.5	1.7	1.4	1.5	1.3	1.8	1.8	1.4	1.7	1.3	1.5	1.8	1.5	1.3	1.6	1.6
Number of self-reported non-cancer illnesses	2.1	3.6	5.1	-2.0	-1.9	-1.8	-1.9	-1.3	-1.5	-1.9	-2.1	-2.2	-1.9	-2.2	-2.2	-2.0	-2.3	-2.0	-1.9	-1.6	-1.6	-1.9	-1.7	-1.4	-2.1
Bipolar Disorder or Schizophrenia	2.0	4.9	8.7	-2.4	-2.6	-2.0	-2.6	-3.0	-2.1	-2.2	-2.2	-1.9	-2.6	-1.9	-2.1	-1.9	-1.9	-2.2	-2.2	-2.7	-2.0	-1.9	-2.2	-0.9	-2.5
Overall health rating	2.0	4.2	6.1	-2.3	-2.4	-2.0	-2.4	-1.9	-2.5	-2.1	-2.2	-1.9	-2.4	-1.9	-2.3	-1.7	-1.8	-1.9	-2.2	-2.3	-1.6	-1.4	-1.8	-1.3	-2.1
Breastfed as a baby	1.9	2.3	4.8	1.5	1.7	1.1	1.3	2.0	1.1	1.4	1.5	1.4	1.8	1.3	1.6	1.4	1.4	1.4	1.4	1.8	2.2	1.3	1.4	1.2	1.9
Comparative height size at age 10	1.9	10.6	17.7	3.3	2.5	4.2	3.6	2.2	4.1	2.8	3.4	3.5	2.3	3.5	2.8	3.7	3.5	3.5	3.3	2.9	1.8	3.8	3.6	3.2	2.7
Asthma (self-reported)	1.9	3.7	5.4	-2.0	-1.8	-1.6	-1.7	-1.2	-1.2	-2.0	-2.0	-2.3	-2.0	-2.3	-2.3	-2.2	-2.3	-2.1	-1.9	-1.5	-1.4	-2.3	-1.7	-1.7	-1.9
Waist Hip Ratio (WHR)	1.8	8.1	13.0	3.1	2.7	2.9	2.9	1.8	2.8	2.8	2.7	3.4	2.6	3.4	2.5	3.2	3.4	3.1	3.1	2.5	1.7	3.6	2.7	2.5	2.5
Respiratory disease	1.8	4.1	6.1	-2.1	-1.9	-1.6	-1.9	-1.3	-1.5	-2.2	-2.2	-2.4	-2.1	-2.4	-2.3	-2.3	-2.5	-2.3	-2.0	-1.6	-1.3	-2.4	-1.8	-1.7	-2.1
Illnesses of father: None of the above (group 1)	1.8	2.2	3.1	1.6	1.3	1.6	1.2	1.0	1.2	1.4	1.6	1.7	1.5	1.7	1.6	1.6	1.7	1.5	1.6	1.2	1.3	1.6	1.2	1.8	1.6
Ever taken oral contraceptive pill	1.8	2.0	2.9	1.6	1.6	1.6	1.5	1.4	1.7	1.4	1.4	1.4	1.2	1.4	1.2	1.3	1.4	1.4	1.6	1.6	1.0	1.2	1.4	1.1	1.4
Alcohol drinker status: Previous	1.8	2.1	4.8	-1.7	-1.5	-0.3	-1.4	-0.6	-0.8	-1.3	-1.1	-2.0	-1.5	-2.2	-1.9	-0.9	-2.1	-1.6	-1.7	-1.3	-1.3	-1.7	-0.9	-0.8	-1.4
Medication: Co-codamol	1.7	1.9	2.6	-1.4	-1.5	-1.6	-1.4	-0.9	-1.4	-1.1	-1.4	-1.5	-1.3	-1.5	-1.5	-1.6	-1.5	-1.6	-1.4	-1.2	-1.3	-1.6	-1.0	-1.2	-1.3
Tense / ‘highly strung’	1.7	2.8	4.5	-1.6	-1.8	-1.3	-1.8	-2.1	-1.7	-2.0	-1.8	-1.5	-2.1	-1.3	-1.9	-1.4	-1.4	-1.3	-1.6	-1.9	-1.7	-1.3	-1.5	-1.5	-1.8
Number of children fathered	1.7	1.9	3.1	1.2	1.4	1.5	1.5	1.8	1.3	1.5	1.5	1.2	1.2	1.0	1.4	1.5	1.2	1.1	1.1	1.6	1.0	1.5	1.4	1.1	1.4
Age when periods started (menarche)	1.6	3.7	6.1	-2.0	-2.3	-2.2	-2.2	-2.0	-2.5	-2.2	-2.2	-1.4	-1.5	-1.5	-1.7	-1.8	-1.3	-1.9	-1.9	-2.4	-1.6	-1.1	-2.2	-1.6	-2.1
Impedance of leg (left)	1.6	7.7	9.5	-3.0	-2.8	-2.5	-3.1	-2.8	-3.1	-2.7	-2.7	-2.6	-2.5	-2.8	-2.9	-2.5	-2.6	-2.6	-3.1	-2.9	-2.7	-2.6	-2.8	-3.0	-2.7
Noisy workplace	1.6	2.0	4.2	-1.6	-1.2	-0.9	-1.4	-0.7	-0.7	-1.1	-1.1	-2.0	-1.5	-2.0	-1.8	-1.4	-2.0	-1.7	-1.6	-1.1	-0.8	-2.0	-1.1	-0.8	-1.0
Medication: Ventolin 100micrograms inhaler	1.6	2.1	5.1	-1.2	-1.2	-1.2	-0.9	-0.5	-0.9	-1.8	-1.6	-1.5	-1.1	-1.7	-2.3	-1.8	-1.6	-1.6	-1.1	-0.9	-1.7	-1.4	-1.1	-2.1	-1.5
Shortness of breath walking on level ground	1.6	1.9	4.0	1.3	1.2	1.7	1.1	0.6	1.2	1.2	1.4	1.5	1.2	1.6	1.2	2.0	1.6	1.8	1.1	0.8	1.0	2.0	0.8	1.5	1.2
Smoking status: Previous	1.6	2.4	4.2	1.5	1.8	2.0	1.8	1.3	2.1	1.8	1.8	1.2	0.9	1.1	1.4	1.5	1.2	1.7	1.2	1.8	1.6	1.0	1.6	1.5	1.7
Intelligence (Savage-Jansen 2018)	1.5	4.6	7.1	2.5	2.2	1.3	2.4	1.9	2.1	2.6	1.8	2.5	2.3	2.6	2.4	1.5	2.4	1.9	2.7	2.2	1.8	2.1	1.9	1.5	2.1
Hand grip strength (left)	1.5	4.0	5.5	2.2	1.9	1.8	2.3	1.6	2.2	1.8	1.9	2.3	1.4	2.3	1.9	1.8	2.3	1.7	2.3	2.0	1.8	2.3	1.9	2.1	1.9
Hand grip strength (right)	1.5	4.0	6.5	2.1	1.9	2.0	2.5	1.8	2.4	1.9	2.1	2.1	1.4	2.0	1.7	1.8	2.1	1.8	2.1	2.1	1.5	2.2	2.1	1.7	2.0
Neck or shoulder pain in last month	1.5	2.2	4.8	-1.6	-1.9	-0.5	-1.2	-1.0	-1.2	-1.7	-1.5	-1.5	-2.0	-1.6	-2.2	-0.9	-1.5	-1.5	-1.5	-1.4	-1.7	-0.9	-0.6	-1.5	-1.8
Schizophrenia (2018)	1.4	2.9	4.5	-1.8	-2.1	-1.5	-2.0	-2.1	-1.6	-1.7	-1.5	-1.6	-2.0	-1.5	-1.7	-1.4	-1.6	-1.9	-1.6	-2.0	-1.5	-1.5	-1.6	-0.5	-1.9
Chronic bronchitis/emphysema (mother)	1.4	1.6	3.2	-1.4	-1.4	-0.9	-1.0	-0.5	-1.2	-1.1	-0.9	-1.8	-1.4	-1.8	-1.0	-1.2	-1.8	-1.8	-1.2	-1.1	-0.8	-1.7	-0.7	-0.9	-1.1
Age at first live birth	1.4	2.4	5.2	2.0	1.6	0.8	1.6	1.0	1.2	1.3	1.1	2.1	1.7	2.3	1.7	1.1	2.1	1.5	2.3	1.4	1.0	1.9	1.0	1.1	1.3
Smoking status: Current	1.4	2.2	4.4	-1.3	-1.2	-2.1	-1.3	-0.8	-1.9	-1.5	-1.8	-1.3	-1.2	-1.3	-1.6	-1.9	-1.3	-1.6	-1.2	-1.3	-1.5	-1.4	-1.4	-2.1	-1.2
Average weekly beer plus cider intake	1.4	2.1	2.8	1.6	1.4	1.5	1.7	1.5	1.5	1.4	1.4	1.5	1.2	1.4	1.1	1.3	1.5	1.3	1.5	1.7	1.2	1.5	1.6	1.0	1.5
Bipolar Disorder (2018)	1.3	2.1	4.2	-1.5	-1.6	-1.4	-1.6	-2.1	-1.4	-1.4	-1.6	-1.1	-1.7	-1.1	-1.2	-1.2	-1.0	-1.2	-1.5	-1.8	-1.4	-1.1	-1.6	-0.9	-1.6
Relative age of first facial hair	1.3	2.6	4.7	-1.7	-1.4	-1.4	-1.0	-0.8	-0.6	-1.4	-1.7	-1.9	-1.8	-1.9	-2.2	-2.0	-2.0	-1.9	-1.5	-1.1	-1.5	-1.7	-1.2	-2.0	-1.7
Diabetes (father)	1.3	1.6	3.5	-1.3	-1.0	-1.9	-1.3	-1.2	-0.9	-1.3	-1.4	-1.3	-0.5	-1.3	-1.0	-1.4	-1.3	-1.2	-1.4	-1.2	-0.5	-1.2	-1.5	-1.5	-1.4
Severe depression (siblings)	1.3	1.5	3.3	1.1	1.2	1.1	1.1	0.7	1.0	1.2	1.4	1.3	1.8	1.3	1.7	1.6	1.3	1.3	1.0	0.8	0.8	1.5	1.0	0.9	1.1
Impedance of leg (right)	1.3	6.3	7.9	-2.8	-2.6	-2.2	-2.8	-2.4	-2.7	-2.5	-2.4	-2.5	-2.3	-2.6	-2.6	-2.3	-2.4	-2.6	-2.8	-2.5	-2.3	-2.5	-2.4	-2.6	-2.5
Current tobacco smoking	1.3	2.2	3.9	-1.3	-1.3	-2.0	-1.4	-0.9	-1.9	-1.4	-1.8	-1.2	-1.3	-1.3	-1.6	-1.8	-1.3	-1.5	-1.2	-1.4	-1.4	-1.3	-1.5	-1.9	-1.3
Nervous feelings	1.3	2.4	6.3	-1.3	-2.1	-1.1	-1.9	-2.3	-2.5	-1.7	-1.7	-0.6	-2.5	-0.4	-1.4	-0.7	-0.5	-1.1	-1.0	-2.0	-1.7	-0.3	-1.0	-0.6	-1.8
Weight	1.3	6.4	9.2	2.5	2.3	3.0	2.3	2.3	2.4	2.1	2.6	2.4	2.4	2.5	2.6	3.0	2.4	2.7	2.4	2.3	2.7	2.9	2.3	3.0	2.4
Hair/balding pattern: Pattern 3	1.3	1.9	3.2	1.5	1.2	1.4	1.6	0.7	1.3	1.4	1.3	1.7	0.3	1.8	1.4	1.4	1.7	1.4	1.6	1.1	0.6	1.7	1.5	1.0	1.3
Asthma	1.3	2.6	4.1	-1.7	-1.6	-1.4	-1.4	-1.0	-1.0	-1.7	-1.7	-1.9	-1.7	-2.0	-2.0	-1.9	-2.0	-1.8	-1.6	-1.2	-1.1	-1.9	-1.4	-1.4	-1.6
Suffer from ‘nerves’	1.3	2.1	4.9	-1.2	-2.0	-1.1	-1.6	-2.2	-2.0	-1.6	-1.6	-0.7	-1.9	-0.5	-1.3	-0.9	-0.6	-1.3	-1.0	-1.9	-1.9	-0.5	-1.2	-1.1	-1.8
Commuting to job workplace: Car/motor vehicle	1.3	1.5	2.5	-1.2	-1.2	-1.3	-1.5	-1.3	-1.4	-1.4	-1.6	-1.0	-1.5	-0.9	-1.4	-1.3	-0.9	-1.0	-1.1	-1.2	-0.5	-0.8	-1.4	-0.9	-1.1
Eye problems/disorders: Cataract	1.3	1.5	3.3	-1.2	-0.7	-1.8	-1.3	-0.3	-1.4	-0.8	-1.1	-1.4	-0.6	-1.5	-0.8	-1.6	-1.4	-1.2	-1.4	-0.8	-0.3	-1.8	-1.3	-1.3	-0.7
HbA1C	1.2	1.3	5.7	-0.9	-0.6	-1.3	-1.0	-1.4	-0.1	-0.9	-0.7	-2.4	-0.8	-0.2	-1.0	-1.0	-2.4	-1.3	-0.8	-1.0	-0.7	-0.8	-1.4	-0.7	-0.4
Past tobacco smoking	1.2	2.1	3.3	-1.6	-1.7	-1.5	-1.8	-1.2	-1.7	-1.6	-1.5	-1.4	-0.9	-1.4	-1.3	-1.2	-1.4	-1.6	-1.4	-1.7	-1.2	-1.1	-1.6	-1.0	-1.7
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.1	-1.3	-1.2	-1.1	-1.4	-0.8	-1.2	-1.2	-1.4	-1.4	-1.2	-1.2	-1.3	-1.2	-1.4	-1.4	-1.2	-1.1	-0.5	-1.1	-1.1	-1.0	-1.2
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.5	1.9	1.7	1.0	1.8	1.4	1.9	1.7	1.5	1.7	1.7	1.9	1.8	1.1	1.7	1.2	2.1	1.7	1.5	1.4	1.5	1.6	1.7
Health satisfaction	1.2	1.5	2.5	-1.3	-0.9	-1.5	-1.3	-1.2	-0.8	-1.0	-1.4	-1.3	-1.1	-1.3	-1.4	-1.3	-1.3	-1.1	-1.4	-1.2	-0.6	-1.2	-1.6	-1.3	-1.1
Osteoarthritis (self-reported)	1.2	1.6	3.5	-1.6	-1.3	-0.8	-1.6	-1.4	-0.8	-0.9	-1.0	-1.7	-1.3	-1.6	-0.9	-0.9	-1.6	-0.8	-1.9	-1.2	-0.2	-1.5	-1.1	0.3	-1.3
Diastolic blood pressure, automated reading	1.2	3.8	5.5	1.9	2.0	1.7	2.2	1.9	1.9	2.4	2.2	1.9	1.8	1.8	1.9	1.8	1.9	2.0	1.8	2.1	1.5	1.8	2.1	1.8	2.2
Heart attack/myocardial infarction (self-reported)	1.2	1.5	2.7	-1.3	-1.0	-1.4	-1.2	-0.4	-1.0	-1.0	-1.3	-1.5	-0.9	-1.6	-1.6	-1.2	-1.6	-1.5	-1.1	-1.0	-0.8	-1.2	-1.0	-1.2	-1.2
Hypothyroidism (self reported)	1.1	2.5	4.5	-1.7	-1.8	-0.8	-1.7	-1.7	-1.0	-2.1	-1.6	-1.6	-1.7	-1.7	-2.1	-1.3	-1.6	-1.3	-1.7	-1.7	-1.2	-1.5	-1.4	-0.9	-1.9
Alcohol usually taken with meals	1.1	1.8	4.4	1.2	1.0	1.0	0.3	0.3	0.3	1.2	1.4	1.5	1.5	1.7	1.8	1.8	1.6	1.5	1.2	0.6	2.0	1.6	0.7	2.1	1.4
Heart attack	1.1	1.4	2.6	-1.3	-1.0	-1.4	-1.1	-0.3	-0.9	-0.9	-1.3	-1.5	-0.9	-1.6	-1.6	-1.2	-1.6	-1.4	-1.2	-1.0	-0.8	-1.2	-0.9	-1.2	-1.2
Medication: Cholesterol lowering	1.1	1.7	2.9	-1.2	-1.2	-1.1	-1.3	-0.9	-1.7	-1.2	-1.4	-1.3	-0.5	-1.3	-1.3	-1.3	-1.4	-1.2	-1.1	-1.3	-1.6	-1.2	-1.5	-1.7	-1.4
Body fat percentage	1.1	4.5	9.3	-2.4	-1.9	-2.2	-3.0	-1.9	-3.0	-2.1	-2.0	-2.3	-1.4	-2.3	-1.6	-1.6	-2.3	-1.7	-2.6	-2.3	-0.8	-1.9	-2.7	-1.5	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.6	1.0	0.7	0.7	0.7	0.5	0.4	1.1	1.1	1.5	0.8	1.5	0.9	1.4	1.5	1.0	1.2	0.8	1.4	1.5	1.4	1.6	1.1
Medication: Gliclazide	1.1	1.2	3.0	-1.2	-1.0	-1.0	-1.2	-1.7	-0.8	-1.2	-1.1	-1.0	-0.8	-1.0	-0.8	-0.9	-0.9	-0.5	-1.4	-1.4	-1.1	-0.9	-1.6	-1.0	-1.2
Prostate Cancer	1.0	1.5	3.1	1.4	1.1	1.0	1.3	1.4	1.1	1.5	1.0	1.3	0.9	1.3	0.9	1.0	1.2	0.6	1.8	1.3	0.8	1.2	1.6	1.2	1.2
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.4	1.1	1.4	0.8	0.6	0.7	0.9	1.3	1.1	1.1	1.5	1.1	1.3	1.2	1.1	1.5	0.9	1.0	1.6	0.8	0.7	1.3	1.4
Illnesses of father: High blood pressure	1.0	1.2	2.0	-1.1	-1.1	-1.1	-0.9	-0.9	-0.9	-1.0	-1.1	-1.1	-1.3	-1.2	-1.2	-1.3	-1.1	-1.2	-0.9	-0.9	-0.9	-1.4	-0.8	-1.1	-1.2
Mean Putamen Volume	0.9	1.0	3.6	0.9	0.7	1.6	1.0	0.7	1.4	0.9	1.1	0.8	0.4	0.8	0.7	1.2	0.8	0.9	1.0	0.9	0.8	0.9	1.0	1.9	0.6
Lung FVC	0.9	4.4	10.6	2.1	2.9	1.1	2.4	3.2	1.8	2.3	2.2	1.3	3.3	1.2	2.2	1.1	1.2	1.9	1.8	2.8	2.4	0.8	1.9	0.5	2.7
Sensitivity / hurt feelings	0.9	1.6	3.2	-1.4	-1.4	-1.0	-1.6	-1.3	-1.8	-1.3	-1.3	-1.2	-1.6	-1.2	-1.0	-1.0	-1.2	-1.3	-1.4	-1.4	-0.5	-1.2	-1.4	-0.8	-1.2
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.2	1.1	1.5	0.9	1.2	1.3	1.1	1.1	1.0	0.7	1.3	0.7	1.0	1.0	0.7	1.3	0.8	1.3	0.9	1.0	1.0	0.3	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.1	-1.1	-0.8	-1.0	-0.9	-0.5	-0.9	-1.1	-1.1	-1.4	-0.7	-1.3	-1.4	-1.2	-1.4	-1.1	-1.2	-0.8	-1.0	-1.3	-0.9	-1.7	-0.9
Neuroticism score	0.9	1.8	4.1	-1.2	-1.7	-0.8	-1.6	-1.9	-1.9	-1.6	-1.5	-0.7	-2.0	-0.7	-1.5	-0.7	-0.6	-1.0	-1.1	-1.6	-1.5	-0.4	-1.1	-0.9	-1.5
Worrier / anxious feelings	0.9	1.8	3.9	-1.5	-1.5	-1.7	-2.0	-1.6	-1.9	-1.2	-1.5	-0.9	-1.3	-0.9	-1.0	-0.8	-0.9	-1.2	-1.5	-1.7	-0.5	-0.4	-1.6	-0.4	-1.3
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	4.0	-1.4	-1.6	-0.9	-1.4	-1.3	-1.0	-1.8	-1.5	-1.1	-1.4	-1.3	-2.0	-1.2	-1.1	-1.3	-1.3	-1.5	-1.4	-1.0	-1.1	-1.0	-1.7
Migraine (self-reported)	0.9	1.1	4.1	-0.7	-1.5	0.2	-0.7	-0.5	-0.8	-1.2	-1.1	-0.7	-1.5	-0.7	-2.0	-0.8	-0.8	-1.6	-0.0	-0.8	-1.7	-0.4	-0.2	-0.5	-1.3
Supplements: Vitamin C	0.9	1.0	2.2	1.0	1.1	0.8	1.5	1.4	1.0	1.1	1.2	0.8	0.9	0.6	0.8	0.7	0.7	1.0	0.9	1.4	0.5	0.6	1.5	0.4	1.3
Average weekly red wine intake	0.9	1.3	2.6	1.3	0.8	1.2	1.0	0.2	0.9	0.8	1.1	1.5	0.9	1.6	1.1	1.3	1.5	1.3	1.5	0.8	0.7	1.4	1.0	1.4	0.9
Medication for cholesterol	0.9	1.3	2.6	-1.0	-1.2	-1.5	-0.7	-1.1	-0.7	-1.2	-1.2	-0.9	-1.0	-0.9	-1.2	-1.6	-0.9	-1.4	-0.6	-1.0	-1.4	-1.3	-0.8	-1.1	-1.4
Medication: Atorvastatin	0.9	1.1	2.0	-1.0	-0.9	-0.9	-1.0	-1.4	-0.5	-0.8	-1.3	-1.0	-1.3	-0.9	-0.9	-0.9	-1.0	-0.7	-1.1	-1.2	-1.2	-0.8	-1.3	-0.7	-1.3
Impedance of whole body	0.9	4.5	6.2	-2.3	-2.0	-1.9	-2.1	-2.0	-2.2	-1.9	-1.9	-2.2	-1.9	-2.3	-2.0	-2.0	-2.2	-2.1	-2.4	-2.1	-2.5	-2.3	-2.0	-2.5	-2.0
Bipolar Disorder (2011)	0.8	0.7	2.0	0.0	-1.1	-0.8	-1.1	-1.4	-0.8	-1.0	-1.1	-0.8	-1.4	0.0	0.0	0.0	0.0	0.0	-1.1	-1.2	-0.7	0.0	-1.1	0.0	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.5	-1.3	-1.0	-1.0	-1.1	-0.5	-1.1	-1.2	-0.9	-1.5	-1.1	-1.6	-1.3	-1.2	-1.6	-1.2	-1.2	-0.9	-0.6	-1.5	-1.0	-0.8	-0.9
Qualifications: None of the above	0.8	1.7	3.1	-1.4	-1.4	-0.8	-1.0	-0.7	-1.5	-1.2	-1.1	-1.4	-1.8	-1.6	-1.8	-1.0	-1.4	-1.3	-1.5	-1.1	-1.7	-1.3	-0.7	-1.7	-1.0
Arm fat percentage (right)	0.8	3.0	6.0	-1.9	-1.4	-1.9	-2.4	-1.4	-2.3	-1.9	-1.7	-2.0	-1.1	-1.9	-1.2	-1.3	-1.9	-1.3	-2.2	-1.9	-0.6	-1.6	-2.3	-1.2	-1.4
Prospective memory result	0.8	0.9	2.2	-0.9	-0.9	-0.3	-0.2	-0.4	-0.1	-1.1	-0.7	-1.3	-0.9	-1.4	-1.2	-1.1	-1.3	-0.8	-1.0	-0.7	-1.2	-1.5	-0.5	-1.3	-1.0
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.3	1.1	1.0	1.5	0.8	0.7	0.8	1.0	1.1	0.9	0.7	0.9	0.9	1.2	0.9	1.2	1.2	0.8	0.7	0.7	0.9	1.4	0.9
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.3	0.6	1.1	0.7	0.7	1.6	0.9	1.2	1.0	0.2	0.9	0.2	0.8	0.9	0.2	0.6	0.5	1.2	1.8	0.4	1.0	1.5	1.1
Medication: Omeprazole	0.8	1.0	2.0	1.1	0.8	1.0	0.8	0.0	1.0	0.6	0.8	1.3	0.5	1.4	1.0	1.2	1.4	1.3	1.1	0.6	0.8	1.2	0.8	0.9	0.8
Medication: Seretide 50 evohaler	0.8	0.9	3.0	-0.8	-1.2	-0.5	-1.1	-1.7	-1.1	-1.2	-0.8	-0.4	-1.4	-0.4	-1.0	-0.5	-0.3	-0.7	-0.6	-1.1	-1.2	-0.5	-0.8	-0.3	-1.1
Alcohol intake frequency.	0.8	2.0	4.5	-1.8	-1.6	-0.6	-1.6	-0.1	-1.3	-1.2	-1.0	-1.9	-1.5	-2.1	-1.7	-0.8	-2.0	-1.9	-1.8	-1.1	-0.6	-1.5	-0.6	-0.7	-1.0
Arm fat percentage (left)	0.8	3.3	6.4	-2.0	-1.4	-2.1	-2.5	-1.5	-2.5	-1.8	-1.7	-2.1	-1.1	-2.0	-1.1	-1.4	-2.0	-1.4	-2.3	-1.9	-0.6	-1.8	-2.4	-1.2	-1.4
Pain type(s) experienced in last month: Hip pain	0.8	1.1	2.2	-0.9	-1.3	-1.0	-1.2	-1.1	-1.1	-1.5	-1.3	-0.7	-0.9	-0.7	-1.2	-1.0	-0.7	-0.8	-0.9	-1.1	-0.7	-0.6	-1.0	-0.7	-1.5
Crohns Disease (2012)	0.7	1.1	1.9	-1.2	-0.9	-0.9	-1.2	-0.7	-0.8	-1.2	-1.0	-1.4	-0.8	-1.2	-1.2	-1.1	-1.4	-1.3	-1.0	-0.7	-0.1	-1.3	-0.8	-0.7	-0.9
Blood Platelet Count	0.7	8.2	12.5	-3.0	-2.6	-2.7	-2.6	-2.4	-2.0	-2.8	-3.0	-3.2	-3.5	-3.2	-3.3	-3.2	-3.2	-2.9	-3.2	-2.4	-2.0	-3.3	-2.4	-2.8	-2.7
Angina	0.7	0.9	1.8	-0.9	-0.8	-1.3	-0.8	-0.4	-0.5	-0.8	-1.0	-1.1	-0.7	-1.1	-1.0	-1.3	-1.1	-1.1	-0.9	-0.8	-0.6	-1.4	-0.6	-1.0	-0.8
Trunk fat percentage	0.7	2.7	6.2	-1.9	-1.4	-1.7	-2.5	-1.5	-2.5	-1.6	-1.5	-1.8	-0.9	-1.7	-1.1	-0.9	-1.7	-1.2	-2.1	-1.9	-0.5	-1.3	-2.1	-1.0	-1.3
Chronic bronchitis/emphysema (father)	0.7	0.8	2.1	0.8	0.7	1.3	1.0	1.4	1.1	1.1	0.9	0.5	0.7	0.4	0.4	0.8	0.4	0.5	1.0	1.1	0.7	0.7	1.2	1.2	0.6
Allergy	0.7	1.5	3.2	1.0	0.8	1.4	0.5	0.8	-0.0	1.5	1.3	1.4	1.1	1.4	1.3	1.8	1.4	1.0	1.2	0.6	1.0	1.7	1.0	1.7	1.3
Impedance of arm (right)	0.7	3.3	5.2	-1.9	-1.8	-1.8	-1.8	-1.8	-1.9	-1.8	-1.7	-1.7	-1.7	-1.8	-1.6	-1.7	-1.7	-1.8	-1.9	-1.9	-2.3	-1.9	-1.7	-2.1	-1.8
Number of live births	0.7	1.0	3.5	-1.0	-1.0	-0.1	-0.3	-0.5	-0.1	-0.5	-0.7	-1.2	-1.9	-1.3	-1.5	-1.0	-1.2	-1.0	-1.1	-0.6	-1.5	-1.3	-0.3	-0.8	-0.7
Pulse wave peak to peak time	0.7	0.8	1.8	1.0	0.7	1.1	0.8	0.2	1.1	0.3	0.8	1.3	0.7	1.2	0.7	1.0	1.3	1.2	1.1	0.4	0.6	1.1	0.6	0.7	0.5
Medication: Aspirin	0.7	0.9	1.4	-1.1	-1.1	-0.8	-1.0	-0.6	-1.0	-0.9	-1.2	-0.8	-0.9	-1.0	-1.1	-0.9	-0.8	-1.0	-1.0	-1.1	-0.9	-0.5	-1.1	-0.8	-1.1
Knee pain experienced in last month	0.7	1.0	2.9	-1.3	-0.8	-0.3	-1.0	-0.7	-0.6	-1.0	-0.8	-1.4	-1.2	-1.6	-0.9	-0.6	-1.4	-0.7	-1.7	-0.7	-0.5	-1.2	-0.9	-0.8	-0.9
Average weekly champagne plus white wine intake	0.7	1.0	1.9	-1.0	-1.2	-0.9	-1.3	-0.9	-1.3	-1.3	-0.9	-1.1	-0.7	-0.9	-0.7	-0.8	-1.1	-1.0	-0.7	-1.4	-0.7	-1.1	-1.1	-0.2	-1.1
Medication: Bendroflumethiazide	0.7	1.0	1.8	1.1	0.8	1.3	0.7	1.0	0.1	1.0	1.0	1.2	1.1	1.1	0.8	1.3	1.2	1.1	1.0	0.9	0.5	1.4	1.0	0.7	1.0
Number of operations (self-reported)	0.7	1.1	2.8	-0.7	-0.7	-0.9	0.1	0.6	0.1	-0.7	-1.0	-1.3	-1.0	-1.2	-1.6	-1.5	-1.4	-1.3	-0.4	-0.1	-1.7	-1.2	0.1	-1.6	-0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	2.1	-0.8	-1.1	-1.1	-0.7	0.0	-1.1	-0.8	-0.8	-0.8	-0.8	-0.9	-1.0	-1.3	-0.9	-1.5	-0.5	-0.6	-0.6	-1.0	-0.4	-0.3	-0.7
Worry (Nagel 2018)	0.6	1.3	4.7	-0.9	-1.5	-0.9	-1.7	-2.2	-1.9	-1.2	-1.2	-0.1	-1.5	-0.0	-0.6	-0.1	0.0	-0.5	-0.9	-1.6	-0.7	0.3	-1.2	-0.0	-1.3
Average weekly fortified wine intake	0.6	0.7	2.1	-0.8	-0.8	-0.7	-0.6	-0.6	-0.8	-0.8	-1.0	-0.7	-1.5	-0.8	-0.8	-1.0	-0.7	-1.0	-0.8	-0.6	-1.0	-0.9	-0.7	-1.1	-0.5
Medication: Lansoprazole	0.6	0.7	1.2	0.9	0.9	0.9	0.9	1.0	1.1	0.8	0.9	0.6	0.9	0.7	0.7	0.9	0.6	0.9	0.9	0.8	0.6	0.7	0.8	1.0	0.8
Length of working week for main job	0.6	0.6	1.3	-0.9	-0.9	-0.7	-1.2	-0.6	-1.1	-0.8	-0.7	-0.9	-0.9	-0.9	-0.6	-0.7	-0.9	-1.0	-0.8	-0.6	0.3	-1.0	-0.8	-0.1	-0.6
Wheeze or whistling in the chest in last year	0.6	1.1	2.2	-1.1	-1.0	-0.6	-1.1	-0.3	-1.0	-1.3	-1.0	-1.2	-0.9	-1.4	-1.5	-1.1	-1.3	-1.3	-0.9	-0.6	-0.5	-1.3	-0.8	-0.8	-1.0
Illnesses of father: Heart disease	0.6	0.9	2.2	-1.1	-0.4	-0.7	-1.1	-0.8	-0.4	-0.9	-0.7	-1.3	-0.7	-1.4	-0.7	-0.8	-1.3	-0.6	-1.4	-0.7	-0.3	-1.5	-1.0	-0.9	-0.8
Mineral and other dietary supplements	0.6	0.8	2.1	-0.6	-0.5	-0.7	-0.5	-0.4	-0.5	-1.0	-1.0	-0.9	-0.7	-0.9	-0.9	-1.4	-0.9	-1.0	-0.5	-0.4	-1.0	-1.4	-0.8	-1.3	-0.8
Alcohol drinker status: Never	0.6	0.7	2.8	0.6	0.7	0.3	0.1	1.0	0.1	0.8	0.8	0.6	1.1	0.6	0.9	0.9	0.6	0.5	0.6	0.9	1.7	0.8	0.5	1.3	1.1
Risk taking	0.6	0.9	1.7	-0.8	-0.8	-0.9	-0.9	-0.4	-1.3	-1.1	-1.1	-0.9	-0.7	-0.9	-1.3	-1.1	-0.9	-1.0	-0.8	-0.8	-0.7	-0.8	-1.1	-1.3	-0.8
Alzheimer’s Disease (including proxy)	0.5	0.7	1.7	-0.7	-0.7	-0.8	-0.8	-0.8	-0.7	-1.3	-0.9	-0.7	-0.4	-0.6	-1.1	-0.8	-0.7	-0.5	-0.7	-0.7	-0.9	-0.6	-0.7	-1.1	-1.0
Age at First Birth	0.5	0.7	1.5	0.8	0.8	0.5	0.4	0.4	0.5	1.1	0.7	1.0	0.8	1.1	1.0	0.9	1.1	0.8	0.8	0.6	1.2	1.1	0.5	1.1	0.8
HDL Cholesterol	0.5	0.9	1.5	1.0	0.8	1.2	1.2	0.8	1.2	0.6	0.9	1.0	0.7	0.9	0.6	0.9	1.0	0.8	1.2	0.9	0.7	1.0	1.2	0.8	0.7
LDL Cholesterol	0.5	0.8	2.4	-0.8	-0.4	-1.4	-0.5	-0.4	-0.4	-0.5	-1.0	-1.1	-0.4	-1.0	-0.6	-1.4	-1.1	-0.9	-0.9	-0.6	-0.5	-1.2	-1.0	-1.5	-0.6
Triglycerides	0.5	0.7	1.4	-1.0	-0.8	-1.1	-0.8	-0.5	-0.8	-0.4	-0.7	-1.1	-0.6	-1.1	-0.5	-1.0	-1.1	-1.1	-1.1	-0.6	-0.4	-1.2	-0.7	-0.7	-0.6
BMI	0.5	2.6	5.4	-1.8	-1.2	-2.1	-2.3	-1.5	-2.2	-1.4	-1.5	-2.0	-0.7	-1.8	-1.0	-1.3	-2.0	-1.2	-2.0	-1.6	-0.2	-1.8	-2.0	-0.8	-1.4
Neuroticism	0.5	1.3	4.1	-1.0	-1.6	-0.3	-1.3	-2.0	-1.3	-1.5	-1.2	-0.4	-1.9	-0.3	-1.2	-0.3	-0.3	-0.7	-0.9	-1.5	-1.4	-0.2	-0.8	-0.5	-1.5
Vitamin and mineral supplements	0.5	0.6	2.2	0.8	1.1	0.6	1.0	1.1	1.5	0.5	0.6	0.6	1.1	0.5	0.5	0.4	0.6	0.6	0.8	1.1	1.0	0.5	0.7	0.2	0.6
Medication: Ramipril	0.5	0.6	1.7	0.5	0.8	0.6	0.6	1.2	0.5	1.2	0.9	0.3	1.0	0.2	1.1	0.6	0.3	0.5	0.2	0.9	1.3	0.2	0.7	0.6	1.1
Illnesses of siblings	0.5	0.7	1.7	-0.7	-1.2	-0.7	-0.9	-1.2	-0.9	-1.1	-1.0	-0.5	-1.3	-0.3	-0.6	-0.8	-0.5	-0.9	-0.4	-1.0	-0.6	-0.6	-0.8	0.2	-1.1
Impedance of arm (left)	0.5	2.2	3.4	-1.6	-1.3	-1.6	-1.4	-1.4	-1.4	-1.2	-1.3	-1.6	-1.2	-1.6	-1.1	-1.5	-1.6	-1.4	-1.7	-1.4	-1.8	-1.9	-1.4	-1.8	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.9	-0.9	-1.1	-0.2	-0.8	-1.1	-1.0	-0.9	-0.9	-0.6	-1.4	-0.6	-0.9	-0.3	-0.6	-0.7	-0.9	-0.9	-0.8	-0.2	-0.4	-0.7	-1.2
Birth weight	0.5	1.0	4.5	1.0	0.8	1.4	1.5	0.4	2.1	0.5	0.6	1.1	-0.0	1.1	0.5	0.8	1.1	1.2	1.0	0.8	0.5	1.2	1.0	0.6	0.5
Exposure to tobacco smoke outside home	0.5	0.7	3.0	-0.5	-1.1	-0.8	-0.9	-0.4	-1.7	-1.3	-1.0	-0.4	-1.2	-0.3	-1.2	-0.6	-0.4	-1.0	-0.0	-0.8	-0.5	-0.2	-0.2	-0.2	-0.9
Pulse rate, automated reading	0.5	1.5	3.0	-1.4	-1.6	-1.6	-1.5	-1.7	-1.4	-0.8	-1.3	-0.8	-1.1	-0.9	-1.0	-1.2	-0.8	-1.2	-1.2	-1.6	-0.6	-0.8	-1.3	-0.2	-1.4
Mood swings	0.5	1.0	2.0	-1.0	-1.0	-0.0	-0.9	-1.4	-0.5	-1.1	-0.9	-0.9	-1.4	-1.0	-1.2	-0.5	-0.9	-0.4	-1.2	-1.2	-1.1	-0.7	-1.1	-0.6	-1.2
Friendships satisfaction	0.5	0.6	2.0	-0.5	-1.0	-0.2	-0.3	-0.5	-0.5	-0.9	-0.7	-0.4	-1.2	-0.5	-1.3	-0.7	-0.5	-0.9	-0.1	-0.8	-1.4	-0.4	-0.1	-0.5	-0.9
Mother’s age at death	0.5	0.7	1.6	0.9	0.9	0.9	0.6	0.6	1.0	0.7	0.6	0.9	1.2	0.8	0.7	0.6	0.8	0.9	1.0	0.8	0.8	0.5	0.4	1.1	0.6
Age started oral contraceptive pill	0.5	0.6	1.3	0.7	0.8	-0.2	0.1	0.3	-0.1	0.7	0.6	0.9	1.1	1.1	1.1	0.6	0.9	0.7	0.7	0.5	1.1	0.7	0.2	1.0	0.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.6	0.7	0.8	0.8	1.2	1.1	1.6	0.9	0.6	0.3	-0.0	0.4	0.6	0.4	0.3	0.3	0.7	1.1	0.7	0.6	1.0	0.7	0.6
Neuroticism (Nagel 2018)	0.4	0.9	3.6	-1.0	-1.2	-0.6	-1.4	-1.9	-1.3	-1.2	-0.9	-0.3	-1.4	-0.3	-0.6	-0.1	-0.3	-0.4	-1.1	-1.4	-0.8	-0.2	-1.0	-0.2	-1.0
Fasting Glucose	0.4	0.5	2.9	-0.4	-0.9	0.2	-0.5	-1.1	-0.6	-1.1	-0.7	0.4	-1.7	-0.1	-1.0	-0.2	0.4	-0.2	-0.6	-0.6	-1.1	0.2	-0.5	-0.5	-0.7
Neuroticism (2016)	0.4	0.6	2.3	-0.9	-0.9	-0.6	-0.8	-1.5	-0.5	-0.7	-0.7	-0.5	-0.9	-0.4	-0.6	-0.4	-0.4	-0.5	-0.8	-1.0	-0.7	-0.4	-0.4	-0.2	-1.0
Blood White Count	0.4	3.1	5.3	-1.9	-1.1	-2.3	-1.7	-1.1	-1.8	-1.6	-1.6	-2.1	-1.0	-2.2	-1.3	-2.0	-2.0	-1.7	-2.2	-1.2	-0.6	-2.3	-1.7	-2.3	-1.3
Allergy or Eczema	0.4	1.1	2.8	-0.8	-0.9	-0.6	-0.4	-0.8	-0.0	-1.7	-1.0	-1.1	-0.9	-1.2	-1.2	-1.2	-1.1	-0.8	-0.9	-0.7	-1.5	-1.3	-0.6	-1.3	-1.4
Serious illness, injury or assault to yourself	0.4	0.4	1.0	-0.6	-0.6	-0.9	-0.6	0.1	-0.8	-0.8	-0.8	-0.7	-0.4	-0.7	-0.9	-0.8	-0.7	-0.9	-0.4	-0.4	-0.1	-0.6	-0.5	-1.0	-0.6
Body mass index (BMI)	0.4	1.7	3.8	-1.4	-1.0	-1.6	-2.0	-0.9	-1.9	-1.4	-1.3	-1.5	-0.6	-1.4	-0.9	-1.0	-1.5	-1.0	-1.6	-1.4	0.0	-1.2	-1.8	-0.7	-1.0
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.0	0.7	0.7	0.1	0.8	0.3	0.9	0.6	0.7	0.7	1.0	0.8	0.9	0.5	0.7	0.8	0.7	0.7	0.8	0.6	0.5	0.8	0.4
Alcohol intake versus 10 years previously	0.4	0.6	2.0	-0.8	-0.9	-0.6	-0.9	-1.2	-0.6	-1.4	-0.9	-0.3	-1.0	-0.4	-1.1	-0.3	-0.2	-0.3	-0.9	-1.0	-0.4	-0.0	-0.7	-0.9	-0.9
Medication: Amlodipine	0.4	0.5	1.7	-0.6	-0.9	-0.6	-0.9	-0.7	-1.3	-0.7	-0.9	-0.5	-0.8	-0.4	-0.5	-0.9	-0.5	-0.9	-0.4	-0.8	-0.5	-0.7	-0.8	-0.5	-0.7
Had major operations	0.4	0.5	1.6	-0.6	-0.4	-1.0	-0.2	-0.0	-0.1	-0.4	-0.7	-0.8	-0.4	-0.9	-0.9	-1.2	-0.9	-0.9	-0.6	-0.1	-0.8	-1.1	-0.3	-1.0	-0.6
Illnesses of siblings: Diabetes	0.4	0.5	1.3	0.6	0.8	0.6	0.3	0.2	0.1	0.7	0.6	1.1	0.8	0.9	0.8	0.9	1.1	1.0	0.3	0.4	0.8	1.1	0.0	0.5	0.9
Medication: Aspirin	0.4	0.6	1.1	-0.8	-0.9	-0.7	-1.0	-0.5	-1.1	-0.6	-1.0	-0.5	-0.4	-0.7	-0.7	-0.6	-0.5	-0.8	-0.8	-1.0	-0.5	-0.2	-1.0	-0.5	-0.9
Wears glasses or contact lenses	0.4	0.5	2.0	-0.5	-1.0	-0.6	-0.7	-1.0	-0.9	-0.5	-0.6	-0.1	-1.1	-0.0	-1.0	-0.4	-0.0	-0.7	-0.2	-0.7	-1.4	-0.3	-0.1	-0.2	-0.5
Commuting to job workplace: Public transport	0.4	0.5	1.3	0.7	0.7	0.7	0.6	0.7	0.8	0.7	0.8	0.4	1.1	0.5	0.8	0.6	0.4	0.5	0.8	0.8	0.7	0.1	0.9	0.6	0.6
Medication: Lisinopril	0.4	0.5	1.0	-0.7	-0.7	-1.0	-0.8	-0.2	-0.9	-0.7	-0.7	-0.6	-0.2	-0.7	-0.6	-0.7	-0.6	-1.0	-0.6	-0.7	-0.3	-0.5	-0.8	-0.6	-0.6
Myopia	0.4	0.6	1.6	0.8	0.6	0.2	0.4	0.1	-0.1	0.4	0.6	1.2	0.5	1.2	0.7	0.9	1.2	1.0	0.8	0.5	0.4	1.1	0.6	0.5	0.9
Lupus	0.3	0.5	3.2	0.1	0.2	0.8	-0.3	-0.4	0.2	0.8	0.6	0.4	-0.2	0.5	0.8	1.0	0.4	0.6	0.0	0.1	1.4	0.4	0.1	1.8	0.7
Smoking Status	0.3	0.8	1.8	-0.8	-0.6	-1.0	-0.8	-0.5	-1.0	-0.8	-1.0	-0.8	-0.8	-0.9	-1.0	-1.2	-0.8	-0.8	-0.8	-0.7	-0.6	-1.1	-1.0	-1.3	-0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.1	-0.5	-0.4	-0.1	-0.4	-0.5	-0.1	-0.8	-0.7	-0.6	-0.7	-0.7	-1.1	-0.5	-0.7	-0.4	-0.6	-0.5	-0.8	-0.6	-0.5	-0.9	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.9	-0.6	-0.6	-0.3	-0.5	-0.7	-0.3	-0.8	-0.6	-0.6	-0.7	-0.7	-0.3	-0.5	-0.6	-0.5	-0.7	-0.8	-0.5	-0.5	-1.0	-0.5	-0.7
Medication for hormone replacement therapy	0.3	0.4	1.8	0.5	0.7	1.3	0.3	0.6	0.5	0.4	0.6	0.4	0.2	0.3	0.4	1.0	0.4	0.8	0.2	0.7	0.9	0.6	0.4	0.5	0.7
Diabetes (mother)	0.3	0.3	1.5	0.7	0.5	0.2	0.5	0.9	-0.2	-0.0	0.5	0.6	1.2	0.5	0.4	0.4	0.5	0.3	0.8	0.6	0.3	0.5	0.7	-0.3	0.5
Townsend deprivation index at recruitment	0.3	0.4	0.8	-0.6	-0.6	-0.3	-0.6	-0.2	-0.7	-0.7	-0.7	-0.8	-0.7	-0.8	-0.8	-0.7	-0.8	-0.7	-0.6	-0.4	-0.6	-0.9	-0.4	-0.8	-0.5
Relative age voice broke	0.3	0.4	1.3	-0.4	-0.1	0.3	0.6	0.4	0.9	0.0	-0.2	-0.7	-1.1	-0.9	-1.0	-0.7	-0.8	-0.5	-0.4	0.3	-0.7	-1.0	0.5	-0.8	-0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.0	0.6	0.9	0.2	0.6	0.9	0.5	0.4	0.5	0.3	0.7	0.3	0.3	0.1	0.2	0.3	0.7	1.0	0.8	-0.1	0.6	-0.0	0.7
Number of incorrect matches in round	0.3	0.5	1.6	0.6	0.2	1.3	0.7	0.3	0.5	0.5	0.7	0.8	-0.1	0.6	0.1	1.0	0.8	0.7	0.6	0.6	-0.1	0.9	1.1	0.7	0.3
Had other major operations	0.3	0.4	1.4	0.5	0.4	0.3	1.2	0.9	1.1	0.6	0.5	0.4	0.4	0.3	0.4	0.1	0.4	0.3	0.5	0.7	-0.4	0.1	1.2	-0.4	0.4
Pain all over the body in last month	0.3	0.3	1.4	0.5	0.5	0.7	0.9	1.2	0.7	0.6	0.3	-0.0	-0.1	-0.1	-0.3	-0.1	-0.1	0.1	0.6	0.8	-0.4	-0.1	0.8	-0.2	0.3
Diabetes (self-reported)	0.3	0.4	2.2	-0.4	-0.7	-0.8	-0.9	-0.8	-1.5	-0.6	-0.6	-0.2	-0.1	-0.2	-0.4	-0.3	-0.1	-0.1	-0.5	-1.0	-0.9	-0.2	-0.8	-0.5	-0.5
Mouth/teeth dental problems: Dentures	0.3	0.5	1.5	-0.8	-0.9	0.2	-1.0	-1.1	-0.7	-0.5	-0.6	-0.5	-1.2	-0.5	-0.7	0.1	-0.4	-0.2	-0.9	-1.1	-0.7	-0.2	-0.7	0.3	-0.8
Exposure to tobacco smoke at home	0.3	0.3	0.8	-0.4	-0.6	-0.5	-0.5	0.1	-0.6	-0.7	-0.7	-0.6	-0.5	-0.6	-0.9	-0.5	-0.6	-0.7	-0.3	-0.5	-0.6	-0.4	-0.4	-0.8	-0.5
High blood pressure (siblings)	0.3	0.5	1.4	0.5	1.1	0.2	0.8	0.8	0.9	0.8	0.8	0.5	1.2	0.3	0.5	0.6	0.5	0.9	0.2	0.8	0.3	0.5	0.6	-0.4	0.9
Emphysema/chronic bronchitis	0.3	0.3	0.9	-0.7	-0.1	-0.7	-1.0	-0.1	-1.0	-0.1	-0.5	-0.8	-0.1	-0.8	-0.5	-0.3	-0.8	-0.4	-0.9	-0.3	-0.0	-0.5	-0.7	-0.3	-0.2
Angina (self-reported)	0.3	0.4	1.2	-0.6	-0.5	-1.0	-0.5	-0.2	-0.2	-0.5	-0.6	-0.8	-0.3	-0.8	-0.6	-0.9	-0.8	-0.8	-0.6	-0.5	-0.2	-1.1	-0.3	-0.6	-0.4
Diabetes diagnosed by doctor	0.3	0.4	1.8	-0.6	-0.8	-0.4	-1.0	-0.9	-1.3	-0.7	-0.5	-0.3	-0.3	-0.4	-0.4	-0.1	-0.3	-0.2	-0.7	-1.0	-0.8	-0.2	-0.9	-0.2	-0.5
Breast cancer (self-reported)	0.3	0.4	1.2	0.7	0.6	0.1	1.1	1.1	0.5	0.3	0.5	0.5	0.8	0.5	0.6	0.1	0.5	0.4	0.7	0.7	-0.2	0.5	0.9	-0.5	0.5
Eye problems/disorders: Glaucoma	0.3	0.4	1.1	-0.7	-0.9	-0.6	-0.5	-0.9	-0.4	-0.7	-0.5	-0.5	-1.1	-0.4	-0.5	-0.4	-0.4	-0.6	-0.5	-0.8	-0.8	-0.4	-0.3	-0.2	-0.7
Irritability	0.3	0.4	1.0	-0.7	-0.5	-0.9	-0.5	-0.5	-0.8	-0.4	-0.5	-0.8	-0.8	-0.9	-0.4	-0.8	-0.8	-0.3	-0.9	-0.6	-0.3	-1.0	-0.6	-0.4	-0.4
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.6	0.5	0.8	0.2	0.7	0.7	1.0	1.3	0.5	0.2	0.7	0.2	0.5	0.2	0.2	0.6	0.3	0.9	0.8	0.2	0.6	0.6	0.5
Heart disease (siblings)	0.3	0.3	1.1	-0.6	0.0	-0.5	-0.2	0.6	-0.2	0.4	-0.2	-1.0	-0.4	-1.0	-0.5	-0.6	-1.0	-0.7	-0.6	0.1	0.1	-1.0	-0.1	-0.6	0.0
Depressed Affect (Nagel 2018)	0.2	0.4	1.8	-0.6	-0.8	0.0	-0.7	-1.4	-0.3	-0.9	-0.5	-0.2	-1.0	-0.3	-0.8	-0.0	-0.2	-0.0	-0.8	-0.9	-1.0	-0.2	-0.5	-0.4	-0.7
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	-0.3	-0.2	-0.6	-0.9	-0.8	-0.8	-0.9	-0.5	-0.1	-0.0	0.0	-0.3	-0.1	-0.0	0.1	-0.3	-0.6	-0.1	0.1	-0.8	-0.3	-0.5
Major Depression (MDD)	0.2	0.2	1.0	0.5	0.4	1.0	0.5	0.4	0.7	0.5	0.5	0.3	0.4	0.4	0.2	0.5	0.3	0.8	0.4	0.4	0.1	0.4	0.5	0.3	0.2
Coronary Artery Disease (CAD)	0.2	0.2	1.1	-0.1	0.4	-0.2	0.0	0.4	0.3	0.7	0.4	-0.5	1.1	-0.5	0.4	-0.1	0.0	-0.0	-0.4	0.3	0.9	-0.6	0.3	0.3	0.4
Ulcerative Colitis	0.2	0.3	1.1	0.5	0.4	0.5	0.4	-0.1	0.5	-0.1	0.2	0.7	0.3	0.7	0.3	0.7	0.8	1.1	0.2	-0.1	-0.4	1.0	0.0	-0.3	0.2
Cardiovascular Disease	0.2	0.6	1.3	-0.9	-0.8	-0.3	-0.7	-0.5	-0.4	-0.5	-0.6	-1.1	-1.0	-1.1	-1.1	-0.6	-1.1	-0.7	-1.0	-0.8	-0.8	-0.9	-0.5	-0.4	-0.6
Systolic blood pressure, automated reading	0.2	0.6	1.5	0.6	0.9	0.7	0.7	0.8	0.5	1.2	1.2	0.5	0.8	0.5	0.9	0.7	0.5	0.9	0.4	0.9	0.7	0.3	0.8	0.9	1.2
Medication: Metformin	0.2	0.3	1.3	-0.4	-0.6	-0.6	-0.7	-0.6	-1.1	-0.6	-0.4	-0.3	-0.2	-0.3	-0.2	-0.3	-0.3	-0.2	-0.4	-0.8	-0.4	-0.4	-0.6	-0.1	-0.3
Maternal smoking around birth	0.2	0.3	1.0	-0.6	-0.8	0.7	-0.7	-1.0	-0.6	-0.5	-0.2	-0.2	-0.8	-0.2	-0.3	0.6	-0.2	-0.0	-0.6	-0.9	-0.6	0.3	-0.5	0.3	-0.6
Fed-up feelings	0.2	0.4	1.1	-0.5	-0.8	0.1	-0.6	-1.0	-0.6	-0.7	-0.6	-0.0	-0.9	-0.1	-0.8	-0.1	0.0	-0.2	-0.5	-0.8	-1.0	0.3	-0.5	-0.4	-0.8
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.7	-0.2	-0.4	-0.7	0.1	-0.6	0.4	-1.3	-0.7	-0.5	-0.3	-0.6	-0.7	-1.1	-0.6	-0.3	-0.3	-0.2	-0.8	-1.1	-0.4	-1.0	-0.9
Multivitamins +/- minerals	0.2	0.3	2.2	-0.4	-0.7	-0.6	-0.9	-0.8	-1.5	0.1	-0.3	-0.2	-0.6	-0.0	0.1	0.0	-0.1	-0.2	-0.5	-0.9	-0.2	0.0	-0.6	0.3	-0.1
Hearing difficulty/problems with background noise	0.2	0.4	1.5	-0.4	-0.4	-0.7	-0.4	0.7	-0.7	-0.5	-0.4	-0.9	-0.1	-0.9	-0.6	-0.9	-0.9	-0.9	-0.1	0.1	0.0	-1.2	0.1	-0.2	-0.3
Hair/balding pattern: Pattern 2	0.2	0.2	1.3	0.4	0.6	-0.3	0.2	0.5	0.4	0.1	0.4	0.4	1.1	0.3	0.6	0.2	0.4	0.5	0.1	0.3	0.6	0.1	0.0	0.2	0.6
Financial difficulties in last 2 years	0.2	0.2	1.5	-0.1	0.1	-0.2	0.4	1.2	0.2	-0.1	-0.3	-0.6	-0.2	-0.6	-0.8	-0.5	-0.6	-0.7	0.1	0.4	0.1	-0.4	0.4	-0.7	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.8	-0.6	-0.5	-0.0	-0.4	-0.4	-0.1	-0.3	-0.6	-0.7	-0.9	-0.8	-0.9	-0.6	-0.7	-0.4	-0.7	-0.5	-0.5	-0.8	-0.6	-0.5	-0.5
Illnesses of mother	0.2	0.3	0.7	-0.3	-0.7	0.0	-0.5	-0.6	-0.6	-0.9	-0.6	-0.0	-0.4	0.0	-0.7	-0.1	-0.0	-0.4	-0.2	-0.6	-0.8	0.3	-0.4	-0.5	-0.7
Blood clot in the leg (DVT)	0.2	0.3	1.8	0.4	0.4	0.6	1.0	0.8	1.3	0.5	0.3	0.2	-0.3	0.2	0.3	0.2	0.1	0.1	0.5	0.8	0.4	0.4	0.7	0.5	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.2	-0.7	0.5	-0.5	-0.7	-0.6	-0.7	-0.3	0.2	-0.5	0.2	-0.4	0.3	0.2	-0.1	0.0	-0.7	-0.5	0.6	-0.3	0.5	-0.7
Medication: Blood pressure	0.2	0.4	1.0	-0.6	-0.5	-0.6	-0.8	-0.2	-1.0	-0.3	-0.7	-0.7	-0.3	-0.7	-0.7	-0.7	-0.7	-0.8	-0.7	-0.5	-0.5	-0.6	-0.7	-0.7	-0.4
Leg fat mass (right)	0.2	0.7	2.4	-1.0	-0.8	-0.7	-1.6	-0.9	-1.4	-1.0	-0.8	-0.8	-0.4	-0.7	-0.6	-0.2	-0.8	-0.4	-1.1	-1.1	0.2	-0.3	-1.2	-0.1	-0.7
Family relationship satisfaction	0.2	0.2	1.0	0.1	-0.4	0.6	0.3	0.3	0.1	-0.5	-0.2	0.1	-0.6	-0.2	-1.0	-0.4	0.0	-0.4	0.3	-0.0	-1.0	-0.2	0.4	-0.7	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.0	0.2	0.6	1.0	0.4	0.6	0.8	-0.1	0.5	-0.2	0.5	-0.2	0.1	0.5	-0.2	0.3	0.0	0.6	0.1	-0.1	0.3	-0.3	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.3	-0.3	-0.2	-0.6	-0.6	-0.9	-0.6	-0.1	-0.5	-0.2	-0.0	-0.1	0.0	-0.4	-0.2	0.1	-0.4	-0.8	-0.9	-0.2	-1.2	-0.2	-0.4
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.5	-0.4	-0.6	-0.2	-0.7	-0.7	-0.6	-0.4	-0.4	-0.4	-0.4	-0.3	-0.6	-0.2	-0.4	-0.5	-0.3	-0.5	-0.0	-0.5	-0.3	0.1	-0.5
Qualifications: nursing, teaching	0.2	0.3	0.7	0.6	0.8	-0.8	0.4	0.6	0.1	0.2	-0.1	0.5	0.8	0.5	0.4	-0.5	0.4	0.3	0.7	0.5	0.4	0.0	-0.1	-0.3	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.6	-0.1	-0.8	-0.8	-0.7	-0.3	-1.3	-1.2	-0.6	-0.1	-0.2	-0.1	-0.7	-0.5	-0.1	-0.5	0.2	-0.6	-0.4	-0.3	-0.2	-0.2	-0.6
Back pain experienced in last month	0.2	0.3	1.4	-0.3	-0.2	-0.2	0.2	0.2	-0.1	-0.7	-0.3	-0.7	0.0	-0.8	-0.5	-0.7	-0.8	-0.4	-0.4	0.0	-0.8	-0.8	-0.2	-1.2	-0.5
Hearing aid user	0.2	0.2	0.9	-0.4	-0.4	-0.0	-0.7	-0.3	-0.5	-0.3	-0.3	-0.8	-0.1	-0.6	-0.5	-0.5	-0.9	-0.5	-0.3	-0.3	0.2	-0.9	-0.4	-0.0	-0.5
Financial situation satisfaction	0.2	0.2	1.2	-0.3	-0.3	-0.3	-0.1	0.1	-0.4	-0.4	-0.4	-0.4	-0.4	-0.6	-0.7	-0.4	-0.4	-0.2	-0.6	-0.3	-0.5	-0.3	-0.2	-1.1	-0.2
Medication: Blood pressure	0.2	0.4	1.1	0.5	0.5	0.4	0.1	0.6	0.0	0.9	0.7	0.5	0.7	0.5	0.8	0.9	0.5	0.7	0.4	0.3	1.0	0.7	0.4	1.1	0.7
Cholesterol lowering medication	0.2	0.2	0.9	0.4	0.8	0.3	0.7	0.5	1.0	0.1	0.5	0.2	0.5	0.1	0.4	0.4	0.2	0.8	0.1	0.5	0.5	0.3	0.3	-0.1	0.6
Pack years of smoking	0.2	0.2	0.9	-0.4	-0.3	-0.8	-0.5	-0.3	-0.7	-0.8	-0.4	-0.2	0.2	-0.3	-0.2	-0.4	-0.2	-0.4	-0.5	-0.4	-0.1	-0.2	-0.4	-0.9	-0.5
Leg fat mass (left)	0.2	0.9	2.6	-1.1	-0.8	-0.8	-1.6	-1.0	-1.5	-1.1	-0.9	-0.9	-0.5	-0.8	-0.7	-0.3	-0.9	-0.4	-1.2	-1.1	0.1	-0.4	-1.4	-0.3	-0.7
Alzheimer’s Disease (in father)	0.1	0.1	0.3	0.3	0.1	-0.1	0.2	0.3	-0.3	-0.4	-0.1	0.3	0.5	0.3	-0.1	-0.2	0.3	0.1	0.4	0.1	-0.2	0.2	0.2	-0.5	-0.1
Crohns Disease (2017)	0.1	0.2	0.6	-0.6	-0.1	-0.4	-0.1	-0.0	0.1	-0.4	-0.2	-0.8	-0.1	-0.8	-0.4	-0.6	-0.8	-0.5	-0.7	0.1	-0.1	-0.7	-0.2	-0.5	-0.2
Ulcerative Colitis (UC)	0.1	0.2	1.4	0.4	0.3	0.1	0.4	0.0	0.1	-0.1	-0.1	0.7	0.1	0.6	0.1	0.5	0.8	0.8	0.2	-0.1	-0.6	1.2	-0.0	-0.6	0.1
Breast Cancer	0.1	0.2	0.8	-0.2	-0.5	-0.9	-0.3	-0.9	-0.3	-0.2	-0.7	0.5	-0.6	0.5	-0.4	-0.3	0.5	-0.2	-0.0	-0.5	-0.2	0.6	-0.1	-0.1	-0.6
Body Mass Index (BMI) (2010)	0.1	0.1	0.4	-0.3	-0.2	-0.5	-0.6	-0.3	-0.6	-0.1	-0.3	-0.3	-0.2	-0.2	0.1	-0.2	-0.3	-0.3	-0.4	-0.3	0.5	-0.3	-0.6	0.2	-0.0
Rheumatoid Arthritis	0.1	0.1	1.0	0.1	0.5	-0.7	-0.4	0.1	-0.3	0.1	-0.1	-0.1	0.4	0.0	0.3	-0.1	-0.1	0.1	0.1	-0.0	1.0	-0.2	-0.5	0.2	0.3
Blood Eosinophil Count	0.1	1.0	2.8	-0.7	-1.2	0.1	-0.4	-0.1	-0.3	-1.4	-1.0	-1.0	-1.1	-1.1	-1.7	-1.1	-1.1	-1.3	-0.4	-0.5	-1.4	-0.9	-0.3	-0.8	-1.4
Heel T-Score	0.1	0.4	1.5	0.7	0.8	-0.5	0.3	0.4	0.3	0.4	0.2	0.9	1.0	0.9	0.7	0.3	0.9	0.7	0.6	0.5	1.2	0.9	-0.1	0.3	0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	0.1	0.2	-0.1	-0.5	-0.5	-0.7	0.3	0.2	0.3	0.5	0.3	0.8	0.6	0.3	0.7	-0.2	-0.3	0.4	0.3	-0.6	0.7	0.3
Lung FEV1/FVC ratio	0.1	0.4	1.3	0.2	-0.1	0.1	-0.2	-1.0	-0.1	0.1	0.2	1.0	0.2	1.0	0.6	0.7	1.1	0.7	0.2	-0.5	0.2	1.1	-0.4	1.1	0.1
Chronotype (morning person)	0.1	0.2	0.9	-0.3	0.1	-0.1	-0.0	0.6	0.0	0.1	0.0	-0.8	-0.3	-0.9	-0.5	-0.3	-0.9	-0.2	-0.4	0.3	-0.2	-1.0	0.0	0.1	0.2
Tanning	0.1	1.3	3.4	1.3	1.1	1.4	1.3	1.9	1.3	0.9	1.2	0.9	1.6	0.8	0.5	0.8	0.8	0.8	1.5	1.3	1.1	0.8	1.2	1.2	1.1
Number of treatments/medications taken	0.1	0.2	0.8	-0.4	-0.7	-0.4	-0.5	-0.4	-0.9	-0.4	-0.6	-0.2	-0.5	-0.3	-0.6	-0.2	-0.2	-0.3	-0.4	-0.5	-0.8	0.2	-0.2	-0.1	-0.7
Average weekly spirits intake	0.1	0.1	0.7	-0.5	0.0	-0.5	-0.4	-0.6	-0.1	0.1	-0.2	-0.4	-0.4	-0.3	-0.0	-0.2	-0.3	0.0	-0.8	-0.3	-0.0	-0.2	-0.7	-0.4	-0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.6	-0.3	-0.0	0.1	0.2	0.0	0.6	0.2	-0.1	-0.4	-0.8	-0.5	-0.7	-0.1	-0.4	-0.3	-0.3	0.3	-0.2	-0.1	0.4	-0.2	-0.2
Pack years adult smoking proportion	0.1	0.2	1.0	-0.4	-0.2	-0.8	-0.3	-0.2	-0.5	-0.8	-0.4	-0.3	0.1	-0.3	-0.2	-0.4	-0.2	-0.3	-0.5	-0.3	-0.2	-0.2	-0.4	-1.0	-0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.7	-0.4	-0.1	0.4	-0.2	0.0	0.0	-0.1	-0.1	-0.4	-0.8	-0.4	-0.5	0.2	-0.4	-0.1	-0.5	0.0	0.4	0.1	-0.0	0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.9	-0.1	-0.0	-1.0	-0.7	0.0	-1.4	-0.2	-0.2	0.1	0.5	0.1	0.0	-0.3	0.1	-0.1	-0.1	-0.3	0.5	-0.1	-0.5	-0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.5	-0.3	-0.6	-0.4	-0.6	-0.1	-0.7	-0.3	-0.2	-0.2	-0.4	-0.2	-0.2	-0.3	-0.2	-0.7	-0.1	-0.3	0.5	-0.4	-0.2	0.5	-0.1
High blood pressure	0.1	0.2	0.5	-0.5	-0.3	-0.4	-0.5	-0.1	-0.7	0.3	-0.2	-0.5	-0.3	-0.6	-0.4	-0.3	-0.5	-0.3	-0.7	-0.4	-0.5	-0.5	-0.3	-0.1	-0.0
Supplements: Glucosamine	0.1	0.2	0.8	0.1	0.4	-0.4	0.2	0.7	0.3	0.8	0.3	-0.1	0.2	-0.0	0.3	0.1	-0.1	0.2	-0.1	0.4	0.9	0.1	0.4	0.4	0.5
Medication: Atenolol	0.1	0.2	1.3	-0.2	0.1	-1.1	-0.4	-0.3	-0.6	0.1	-0.2	0.1	0.9	0.1	0.5	-0.2	0.2	0.0	-0.5	-0.3	0.2	0.2	-0.5	-0.5	0.0
Medication: Levothyroxine sodium	0.1	0.2	0.5	-0.1	-0.5	0.1	-0.4	-0.7	-0.4	-0.7	-0.3	0.4	-0.3	0.2	-0.6	0.2	0.4	0.1	-0.1	-0.6	-0.6	0.5	-0.1	0.2	-0.5
High blood pressure (mother)	0.1	0.1	0.4	0.2	0.3	-0.5	0.4	-0.3	0.2	0.6	0.2	0.3	0.2	0.3	0.5	-0.1	0.3	0.4	-0.1	0.1	-0.1	-0.1	0.1	-0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.9	-0.0	-0.2	-0.3	-0.7	0.2	-0.9	-0.1	-0.1	0.1	0.4	0.2	0.1	0.1	0.1	-0.0	0.1	-0.4	0.8	0.1	-0.2	0.7	0.2
Mouth/teeth dental problems	0.1	0.2	0.6	0.2	0.4	-0.3	0.7	0.2	0.8	0.6	0.3	0.3	0.6	0.3	0.7	-0.1	0.3	0.1	0.1	0.5	0.1	0.3	0.2	-0.6	0.3
Medication: Simvastatin	0.1	0.1	0.6	0.2	0.4	0.1	0.1	0.6	-0.3	0.0	0.1	-0.1	0.8	-0.1	0.1	-0.0	-0.1	0.2	0.1	0.3	-0.2	-0.1	-0.1	-0.5	0.2
Hip circumference	0.1	0.5	1.5	-0.8	-0.6	-0.6	-1.1	-0.2	-1.2	-0.9	-0.6	-0.9	-0.2	-0.8	-0.3	-0.3	-0.9	-0.6	-0.8	-0.7	-0.0	-0.4	-1.0	-0.4	-0.4
Father’s age at death	0.1	0.1	0.7	0.0	0.3	-0.8	0.1	0.2	-0.1	0.0	-0.2	0.1	0.3	0.1	0.4	-0.5	0.1	-0.2	0.1	0.1	0.4	-0.0	-0.3	-0.1	0.0
Falls in the last year	0.1	0.1	0.3	-0.1	0.1	0.3	0.2	0.3	0.5	0.0	0.3	-0.3	-0.3	-0.4	-0.3	0.1	-0.3	0.0	-0.2	0.4	0.1	-0.5	0.4	0.4	0.3
Pulse rate	0.1	0.1	1.1	0.1	0.1	-0.4	-0.3	-0.1	-0.2	0.2	-0.1	0.3	0.4	0.3	0.3	0.1	0.3	0.3	0.1	0.1	1.0	0.2	-0.2	0.6	0.1
Happiness	0.1	0.1	0.8	0.2	0.5	0.7	0.5	0.5	0.9	0.3	0.3	-0.0	0.1	-0.1	-0.0	0.3	-0.0	0.4	-0.1	0.3	0.0	0.0	0.1	-0.5	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.7	0.4	0.2	0.2	0.5	-0.3	0.3	-0.0	0.3	0.6	0.3	0.6	0.4	0.3	0.6	0.8	0.3	0.1	-0.2	0.5	0.4	-0.1	0.2
Depression (self-reported)	0.1	0.1	0.5	0.0	-0.2	0.5	-0.3	0.3	-0.1	-0.6	-0.1	-0.2	0.4	-0.2	-0.1	0.1	-0.2	-0.2	0.2	-0.1	0.2	-0.0	-0.1	0.7	-0.4
Lung cancer (father)	0.1	0.1	0.9	-0.2	-0.5	-0.1	-0.6	-0.2	-1.0	-0.0	-0.1	0.1	-0.0	0.0	-0.2	0.1	0.1	-0.5	-0.1	-0.4	-0.3	0.1	-0.1	-0.1	-0.0
Pulse wave Arterial Stiffness index	0.1	0.1	0.5	-0.4	-0.2	-0.3	-0.1	0.4	-0.4	0.4	-0.1	-0.7	-0.3	-0.6	-0.1	-0.3	-0.7	-0.6	-0.4	0.2	-0.1	-0.4	0.2	0.0	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.6	0.2	-0.2	-0.7	-0.5	-0.5	-0.6	0.0	-0.2	0.5	0.3	0.7	0.4	-0.3	0.5	-0.1	0.5	-0.2	0.7	0.2	-0.3	0.6	0.1
Medication: Paracetamol	0.1	0.2	0.8	0.6	0.1	0.8	0.9	0.3	0.7	-0.0	0.1	0.4	-0.2	0.4	-0.1	0.3	0.4	0.5	0.6	0.4	-0.6	0.5	0.8	-0.1	-0.2
Headache pain in last month	0.1	0.2	0.5	-0.2	-0.3	0.0	0.4	0.5	0.5	-0.3	-0.4	-0.4	-0.5	-0.5	-0.7	-0.5	-0.5	-0.6	-0.1	0.2	-0.1	-0.1	0.2	-0.6	-0.4
Glaucoma (self-reported)	0.1	0.1	0.5	0.0	-0.3	0.5	0.1	-0.7	0.3	0.0	0.2	0.2	-0.6	0.3	0.1	0.5	0.2	0.2	0.1	-0.2	-0.6	0.3	0.3	0.4	-0.3
Comparative body size at age 10	0.1	0.3	1.7	-0.4	-0.4	-0.9	-1.1	-0.8	-1.3	-0.3	-0.3	-0.1	0.4	-0.0	0.1	-0.0	-0.0	-0.1	-0.5	-0.8	0.4	-0.1	-0.7	-0.0	-0.3
Worry too long after embarrassment	0.1	0.2	1.0	0.3	0.2	-0.1	-0.2	-0.4	-0.5	-0.0	-0.0	0.9	0.1	1.0	0.5	0.6	0.9	0.5	0.3	0.1	0.2	1.0	0.2	0.3	0.3
Medication for pain relief, constipation, heartburn	0.1	0.2	1.7	0.1	0.4	-0.3	-0.2	0.5	-0.0	0.7	0.5	-0.1	0.6	0.1	0.6	0.1	-0.1	-0.3	0.1	0.3	1.3	-0.4	0.0	0.4	0.9
Medication: Ibuprofen	0.1	0.1	0.5	0.0	-0.2	-0.3	0.1	-0.7	-0.2	-0.3	-0.1	0.3	0.1	0.3	0.3	-0.0	0.4	0.5	-0.1	-0.3	-0.4	0.2	-0.0	-0.2	-0.2
Heart disease (mother)	0.1	0.1	0.4	-0.3	-0.3	0.2	-0.2	0.1	-0.1	-0.2	-0.1	-0.4	-0.4	-0.6	-0.7	-0.0	-0.5	-0.2	-0.3	-0.3	-0.3	-0.4	0.0	0.2	-0.2
Number of full sisters	0.1	0.1	0.4	-0.2	0.2	0.6	-0.3	0.6	-0.1	0.2	0.2	-0.4	0.2	-0.6	0.0	0.3	-0.5	-0.2	-0.3	0.2	0.7	-0.2	-0.1	0.1	0.2
Chest pain or discomfort	0.1	0.1	0.3	0.4	0.2	0.1	0.2	0.3	0.1	-0.0	0.1	0.3	0.1	0.3	0.1	0.2	0.3	0.2	0.5	0.2	0.5	0.3	0.4	0.3	0.3
Long-standing illness, disability or infirmity	0.1	0.2	0.7	-0.3	-0.5	-0.5	-0.7	-0.0	-0.8	-0.6	-0.5	-0.4	0.2	-0.4	-0.5	-0.3	-0.4	-0.3	-0.3	-0.4	-0.1	-0.4	-0.3	-0.3	-0.4
Ever had bowel cancer screening	0.1	0.1	0.6	-0.2	0.2	-0.6	-0.3	0.0	-0.3	0.2	-0.0	-0.1	0.8	-0.1	0.1	-0.0	-0.0	0.1	-0.3	0.1	0.3	0.0	-0.1	-0.2	0.1
Osteoporosis (self-reported)	0.1	0.1	0.4	-0.3	-0.1	-0.2	-0.2	-0.5	0.0	0.2	-0.1	-0.4	-0.6	-0.2	0.0	-0.1	-0.4	0.0	-0.4	-0.0	0.1	-0.5	-0.0	0.2	-0.2
Medication: Paracetamol	0.1	0.1	0.8	0.1	-0.3	0.6	0.5	-0.0	0.4	-0.2	-0.1	0.0	-0.5	-0.1	-0.4	-0.0	-0.0	0.0	0.2	0.0	-0.9	-0.0	0.6	-0.1	-0.6
Ever depressed for a whole week	0.1	0.1	0.3	0.0	-0.1	-0.1	-0.2	-0.3	-0.4	-0.3	-0.4	-0.0	-0.4	0.1	-0.2	-0.2	-0.0	-0.2	0.1	-0.2	-0.2	0.0	-0.4	-0.5	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.7	0.7	0.4	0.6	0.6	0.1	0.8	-0.1	0.3	0.7	0.2	0.8	0.4	0.4	0.7	0.5	0.8	0.6	0.6	0.7	0.5	0.4	0.2
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.4	0.4	0.0	0.4	0.4	-0.2	0.6	0.1	0.1	0.6	-0.3	0.6	0.2	0.5	0.6	0.4	0.4	0.1	-0.2	0.6	0.5	0.2	0.1
Supplements: Calcium	0.1	0.1	0.6	0.2	0.0	-0.1	0.1	-0.2	-0.8	0.4	0.2	0.6	-0.2	0.4	0.2	0.5	0.6	0.3	0.1	-0.1	-0.5	0.7	0.2	-0.1	0.3
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.1	-0.1	-0.1	-0.0	0.1	0.2	0.4	0.2	0.0	0.2	0.1	0.4	0.3	0.1	-0.1	-0.1	0.0	0.7	0.2	0.2	0.3	0.2
Depression (Nagel 2018)	0.0	0.0	0.1	-0.0	-0.1	0.1	-0.1	-0.2	-0.1	-0.2	-0.0	0.2	-0.0	0.1	-0.3	0.2	0.2	0.1	-0.1	-0.2	-0.3	0.2	-0.0	-0.2	0.0
Irritable Bowel Disease (IBD)	0.0	0.0	0.3	-0.2	-0.0	-0.1	0.0	-0.1	0.0	-0.4	-0.3	-0.0	-0.2	-0.1	-0.2	-0.0	-0.0	0.1	-0.3	-0.1	-0.4	0.3	-0.2	-0.5	-0.1
Reaction Time	0.0	0.1	0.2	-0.2	-0.4	0.3	-0.3	-0.3	-0.2	-0.1	-0.2	-0.1	-0.5	-0.0	-0.4	0.2	-0.1	-0.0	-0.1	-0.5	-0.3	0.2	-0.1	0.1	-0.1
Blood Red Count	0.0	0.4	1.2	-0.9	-0.2	-0.9	-0.6	-0.2	-0.3	-0.1	-0.5	-0.9	-0.3	-1.0	-0.1	-0.6	-0.9	-0.8	-1.1	-0.3	-0.0	-0.6	-0.7	-0.6	-0.3
Systolic Blood Pressure	0.0	0.2	0.6	-0.4	-0.2	-0.4	-0.1	-0.1	-0.3	0.0	-0.1	-0.6	-0.1	-0.6	-0.3	-0.6	-0.6	-0.3	-0.6	-0.2	-0.6	-0.8	-0.3	-0.3	-0.1
Hair Pigment	0.0	0.7	1.8	-0.9	-1.1	-0.1	-0.8	-0.2	-0.8	-1.2	-0.6	-1.1	-0.6	-1.1	-1.4	-0.5	-1.1	-1.1	-0.7	-0.6	-0.7	-0.8	-0.1	-0.2	-1.0
Taking other prescription medications	0.0	0.1	0.4	-0.1	0.1	0.2	0.0	0.6	0.1	0.2	0.1	-0.2	0.2	-0.3	-0.2	0.1	-0.2	-0.1	-0.1	0.4	0.2	0.1	0.5	0.2	0.0
Trunk fat mass	0.0	0.2	0.8	0.0	0.2	0.3	-0.4	0.1	-0.4	0.1	0.3	0.1	0.6	0.2	0.6	0.8	0.1	0.6	-0.1	-0.1	0.9	0.5	-0.2	0.7	0.4
Waist circumference	0.0	0.1	0.4	-0.1	0.2	0.1	-0.4	0.2	-0.4	-0.1	0.1	-0.1	0.5	-0.0	0.2	0.5	-0.0	0.3	-0.2	-0.1	0.6	0.5	-0.3	0.3	0.2
Arm fat mass (right)	0.0	0.1	0.7	-0.1	0.2	0.2	-0.5	0.2	-0.4	-0.3	0.1	-0.2	0.4	-0.2	0.3	0.5	-0.2	0.4	-0.3	-0.1	0.8	0.3	-0.4	0.6	0.2
Loud music exposure frequency	0.0	0.0	0.3	0.0	-0.1	-0.2	-0.2	-0.2	0.1	-0.5	-0.1	0.1	-0.1	0.2	-0.1	-0.1	0.1	0.1	0.2	-0.0	0.4	-0.0	0.0	0.5	-0.2
Mean time to correctly identify matches	0.0	0.1	0.4	-0.0	0.0	0.6	-0.2	0.3	0.0	0.1	0.1	-0.1	-0.1	-0.0	-0.2	0.5	-0.1	0.2	-0.1	-0.0	0.2	0.2	0.2	0.4	0.3
Whole body fat mass	0.0	0.2	0.8	-0.4	-0.2	-0.2	-0.9	-0.2	-0.8	-0.5	-0.2	-0.4	0.1	-0.3	0.0	0.2	-0.4	0.0	-0.6	-0.5	0.6	0.0	-0.7	0.3	-0.1
Hypertension (Self-reported)	0.0	0.1	0.5	-0.1	0.2	0.1	-0.0	0.6	-0.0	0.7	0.2	-0.2	0.0	-0.4	-0.1	0.1	-0.3	-0.1	-0.3	0.2	0.2	-0.2	0.2	0.4	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.2	0.1	-0.2	0.3	0.2	0.0	0.4	0.1	0.1	0.2	-0.3	0.1	-0.1	0.1	0.1	-0.1	0.1	0.0	-0.2	0.1	0.2	0.3	-0.1
Arm fat mass (left)	0.0	0.1	0.5	-0.2	0.1	-0.1	-0.6	0.1	-0.4	-0.3	-0.0	-0.3	0.3	-0.2	0.3	0.4	-0.3	0.3	-0.4	-0.2	0.7	0.1	-0.5	0.5	0.1
Miserableness	0.0	0.1	0.2	-0.2	-0.0	0.2	-0.1	-0.1	-0.0	-0.5	-0.1	-0.3	-0.3	-0.4	-0.4	0.1	-0.3	0.1	-0.4	-0.0	-0.3	-0.2	-0.2	-0.5	-0.1
Guilty feelings	0.0	0.1	0.3	0.1	-0.1	-0.1	-0.1	-0.3	-0.1	-0.2	-0.3	0.4	-0.3	0.4	-0.3	0.1	0.5	0.1	0.2	-0.3	-0.4	0.6	-0.0	0.1	-0.1
High cholesterol (Self-reported)	0.0	0.0	0.2	0.1	0.1	0.0	0.1	-0.2	0.1	-0.1	-0.1	0.1	0.3	0.0	-0.1	0.0	0.0	0.3	-0.0	-0.1	-0.4	0.1	-0.2	-0.2	-0.1

Hub : Genes

C2orf52

Models

Trait associations