Best TWAS P=2.17e-09 · Best GWAS P=2.57e-10 conditioned to 0.0674
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SLC25A37 | 0.13 | 0.05 | lasso | 5 | 0.04 | 3.0e-04 | -5.8 | 5.6 | 2.6e-08 | -0.12 | 0.10 | 0.86 | TRUE |
| 2 | YFS | Blood | R3HCC1 | 0.03 | 0.01 | lasso | 6 | 0.01 | 5.3e-04 | -5.6 | 5.4 | 5.5e-08 | -0.73 | 0.02 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LOXL2 | 0.16 | 0.03 | lasso | 4 | 0.05 | 1.2e-03 | -4.6 | 5.3 | 1.4e-07 | -0.15 | 0.12 | 0.04 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CHMP7 | 0.03 | 0.03 | blup | 89 | 0.01 | 3.8e-02 | 3.2 | -5.2 | 2.0e-07 | 0.51 | 0.06 | 0.15 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | CHMP7 | 0.10 | 0.02 | lasso | 6 | 0.04 | 5.4e-05 | 3.2 | -6.0 | 2.2e-09 | 0.74 | 0.00 | 0.98 | TRUE |