[Hub]/) : Traits : Leg predicted mass (left) :

chr19:18,740,208-20,451,172

Best TWAS P=4.54e-10 · Best GWAS P=2.37e-10 conditioned to 0.0115

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts ATP13A1 0.14 0.06 lasso 5 0.05 2.2e-04 -5.3 -5.5 3.0e-08 0.89 0.04 0.91 FALSE
2 GTEx Cells Transformed fibroblasts GATAD2A 0.07 0.00 lasso 4 0.00 8.1e-01 -4.6 -6.2 4.5e-10 0.75 0.03 0.72 TRUE
3 GTEx Muscle Skeletal MAU2 0.09 0.04 lasso 4 0.05 5.1e-06 -4.9 5.4 6.7e-08 -0.52 0.86 0.14 FALSE
4 GTEx Whole Blood GATAD2A 0.06 0.02 lasso 9 0.03 1.7e-03 -4.8 -5.5 3.4e-08 0.56 0.49 0.36 FALSE
5 ROSMAP Brain Pre-frontal Cortex ATP13A1 0.10 0.07 lasso 5 0.06 1.3e-08 -5.7 5.7 1.2e-08 -0.82 0.05 0.95 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma HAPLN4 0.05 0.07 lasso 2 0.06 1.1e-07 -4.9 -5.2 1.5e-07 0.41 0.20 0.80 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TM6SF2 0.04 0.03 blup 35 0.03 2.5e-04 -4.9 -5.5 4.5e-08 0.66 0.13 0.67 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma GATAD2A 0.04 0.03 lasso 2 0.03 2.9e-04 -4.6 -5.2 1.5e-07 0.45 0.08 0.78 FALSE