[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr17:75,977,988-79,637,565

Best TWAS P=1.33e-11 · Best GWAS P=9.82e-17 conditioned to 1.63e-17

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Brain Nucleus accumbens basal ganglia	USP36	0.36	0.23	lasso	5	0.20	4.8e-06	6.7	-6.8	1.3e-11	0.02	0.01	0.98	TRUE
7	GTEx	Lung	CBX8	0.28	0.19	enet	24	0.18	1.4e-13	-5.7	5.7	1.5e-08	0.04	0.00	1.00	TRUE
9	GTEx	Muscle Skeletal	RPTOR	0.14	0.05	enet	27	0.09	8.4e-09	-4.4	-5.6	1.8e-08	-0.02	0.98	0.00	TRUE
2	GTEx	Brain Cerebellar Hemisphere	USP36	0.50	0.16	enet	20	0.07	5.7e-03	5.9	-6.3	3.4e-10	-0.03	0.05	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	USP36	0.14	0.13	lasso	3	0.13	1.7e-15	5.9	-6.0	2.2e-09	0.02	0.05	0.95	FALSE
11	GTEx	Testis	USP36	0.32	0.24	lasso	6	0.26	6.2e-12	5.2	-6.0	2.3e-09	0.03	0.12	0.88	FALSE
8	GTEx	Muscle Skeletal	CYTH1	0.13	0.12	lasso	3	0.13	2.5e-12	6.1	5.9	3.8e-09	-0.02	0.14	0.86	FALSE
5	GTEx	Esophagus Mucosa	USP36	0.11	0.04	enet	13	0.06	1.1e-04	6.1	-5.8	8.0e-09	0.04	0.03	0.96	FALSE
12	GTEx	Thyroid	USP36	0.21	0.15	enet	45	0.16	1.6e-12	5.7	-5.7	1.4e-08	0.05	0.38	0.62	FALSE
10	GTEx	Nerve Tibial	CBX8	0.16	0.14	lasso	4	0.14	5.3e-10	-5.5	5.7	1.5e-08	0.05	0.00	1.00	FALSE
4	GTEx	Cells Transformed fibroblasts	CBX8	0.21	0.10	lasso	3	0.08	1.4e-06	-5.5	5.5	3.6e-08	0.05	0.00	1.00	FALSE
6	GTEx	Esophagus Muscularis	USP36	0.18	0.16	lasso	3	0.08	2.5e-05	5.9	5.5	3.8e-08	0.00	0.09	0.91	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	USP36	0.10	0.02	lasso	4	0.05	6.6e-03	6.5	-5.4	8.5e-08	0.06	0.02	0.85	FALSE
13	GTEx	Thyroid	CYTH1	0.24	0.07	lasso	11	0.06	3.4e-05	6.0	5.2	1.8e-07	-0.04	0.05	0.94	FALSE