[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr10:101,548,177-103,428,898

Best TWAS P=1.06e-23 · Best GWAS P=3.04e-22 conditioned to 0.808

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SEC31B	0.13	0.21	lasso	3	0.20	4.1e-24	-5.3	5.3	1.1e-07	0.05	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	SEC31B	0.32	0.39	lasso	5	0.38	5.1e-33	-5.3	5.2	1.7e-07	0.06	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	RP11-179B2.2	0.15	0.08	lasso	6	0.08	3.2e-07	8.3	8.7	3.1e-18	0.92	0.01	0.99	FALSE
4	GTEx	Adipose Visceral Omentum	RP11-179B2.2	0.13	0.02	lasso	3	0.03	6.5e-03	9.6	9.3	1.4e-20	0.98	0.01	0.99	FALSE
5	GTEx	Artery Aorta	RP11-179B2.2	0.16	0.11	lasso	2	0.09	7.6e-06	9.6	9.5	2.0e-21	0.97	0.00	0.99	FALSE
6	GTEx	Artery Tibial	RP11-179B2.2	0.11	0.09	lasso	4	0.08	8.8e-07	9.6	9.6	6.4e-22	0.95	0.00	0.99	FALSE
7	GTEx	Brain Cerebellum	RP11-179B2.2	0.37	0.21	lasso	4	0.20	1.4e-06	9.7	10.0	1.1e-23	0.94	0.00	0.99	TRUE
8	GTEx	Brain Frontal Cortex BA9	RP11-179B2.2	0.22	0.15	lasso	2	0.11	7.2e-04	9.7	9.2	4.8e-20	0.97	0.01	0.96	FALSE
9	GTEx	Breast Mammary Tissue	RP11-179B2.2	0.11	0.09	lasso	2	0.07	1.8e-04	9.6	9.2	2.5e-20	0.97	0.01	0.99	FALSE
10	GTEx	Breast Mammary Tissue (Male)	SEC31B	0.13	0.08	lasso	4	0.10	3.0e-03	-5.3	5.3	1.4e-07	0.05	0.27	0.04	FALSE
11	GTEx	Breast Mammary Tissue (Male)	RP11-179B2.2	0.16	-0.01	enet	4	-0.01	7.1e-01	-9.0	9.1	7.2e-20	0.78	0.03	0.49	FALSE
12	GTEx	Breast Mammary Tissue (Female)	RP11-179B2.2	0.19	0.00	lasso	3	-0.01	5.1e-01	8.3	5.8	4.9e-09	0.66	0.03	0.42	FALSE
13	GTEx	Colon Transverse	SEC31B	0.28	0.12	lasso	3	0.09	3.3e-05	-5.3	5.3	8.7e-08	0.07	0.98	0.00	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	SEC31B	0.15	0.21	lasso	4	0.20	8.0e-08	-5.3	5.3	1.4e-07	0.05	0.96	0.00	FALSE
15	GTEx	Esophagus Mucosa	SEC31B	0.14	0.18	lasso	4	0.17	2.0e-11	-5.3	5.3	1.4e-07	0.05	1.00	0.00	FALSE
16	GTEx	Esophagus Mucosa	HIF1AN	0.14	0.08	lasso	7	0.09	2.2e-06	-5.4	5.3	8.7e-08	0.09	0.98	0.00	FALSE
17	GTEx	Esophagus Muscularis	SEC31B	0.18	0.19	lasso	4	0.20	4.5e-12	-5.3	5.2	1.5e-07	0.05	1.00	0.00	FALSE
18	GTEx	Esophagus Muscularis	RP11-179B2.2	0.15	0.16	lasso	3	0.16	8.1e-10	9.7	9.7	3.0e-22	1.00	0.00	1.00	FALSE
19	GTEx	Heart Left Ventricle	RP11-179B2.2	0.15	0.18	enet	2	0.14	4.8e-08	9.7	9.7	5.0e-22	0.98	0.00	1.00	FALSE
20	GTEx	Lung	RP11-179B2.2	0.18	0.12	lasso	3	0.12	1.7e-09	9.7	9.3	1.1e-20	0.98	0.00	1.00	FALSE
21	GTEx	Muscle Skeletal	HIF1AN	0.05	0.06	lasso	1	0.05	1.6e-05	-5.3	-5.3	1.1e-07	-0.06	0.94	0.00	FALSE
22	GTEx	Nerve Tibial	RP11-179B2.2	0.15	0.08	lasso	2	0.12	6.4e-09	9.7	7.9	3.7e-15	0.91	0.00	1.00	FALSE
23	GTEx	Pancreas	SEC31B	0.24	0.19	lasso	5	0.17	9.9e-08	-5.3	5.2	2.4e-07	0.06	0.97	0.00	FALSE
24	GTEx	Prostate	SEC31B	0.18	0.14	lasso	2	0.12	6.7e-04	-5.2	5.2	1.5e-07	0.05	0.38	0.05	FALSE
25	GTEx	Skin Not Sun Exposed Suprapubic	SEC31B	0.15	0.16	lasso	4	0.15	8.3e-09	-5.3	5.3	1.4e-07	0.05	0.99	0.00	FALSE
26	GTEx	Skin Not Sun Exposed Suprapubic	HIF1AN	0.13	0.03	lasso	5	0.02	3.4e-02	-5.3	5.5	3.1e-08	0.04	0.26	0.03	TRUE
27	GTEx	Skin Not Sun Exposed Suprapubic	RP11-179B2.2	0.27	0.15	enet	36	0.15	2.0e-08	9.7	8.8	1.9e-18	0.74	0.00	1.00	FALSE
28	GTEx	Skin Sun Exposed Lower leg	HIF1AN	0.07	0.05	lasso	8	0.03	2.2e-03	-5.5	5.2	1.8e-07	0.06	0.93	0.00	FALSE
29	GTEx	Skin Sun Exposed Lower leg	RP11-179B2.2	0.12	0.09	lasso	2	0.08	1.7e-07	8.2	7.8	4.2e-15	0.89	0.04	0.96	FALSE
30	GTEx	Spleen	SEC31B	0.21	0.12	lasso	3	0.05	2.3e-02	-5.3	5.4	7.5e-08	0.06	0.28	0.09	FALSE
31	GTEx	Testis	SEC31B	0.11	0.11	lasso	5	0.08	2.5e-04	-5.3	5.3	1.1e-07	0.05	0.84	0.01	FALSE
32	GTEx	Testis	HIF1AN	0.12	0.08	lasso	3	0.06	1.6e-03	-5.4	5.5	3.1e-08	0.08	0.34	0.04	FALSE
33	GTEx	Thyroid	RP11-179B2.2	0.18	0.12	lasso	7	0.11	8.3e-09	8.3	8.8	1.1e-18	0.93	0.03	0.97	FALSE
34	GTEx	Whole Blood	HIF1AN	0.15	0.12	enet	7	0.12	8.7e-11	-5.4	5.4	6.8e-08	0.06	1.00	0.00	FALSE
35	METSIM	Adipose	MRPL43	0.05	0.04	bslmm	422	0.04	1.9e-06	-4.0	6.6	5.5e-11	0.48	0.94	0.02	FALSE
36	NTR	Blood	HIF1AN	0.02	0.03	lasso	2	0.02	1.4e-07	-5.3	5.3	9.0e-08	0.06	1.00	0.00	FALSE
37	NTR	Blood	SEC31B	0.03	0.03	lasso	4	0.03	1.1e-10	-5.3	5.3	1.4e-07	0.06	1.00	0.00	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	MRPL43	0.10	0.08	bslmm	411	0.09	1.2e-11	-4.0	-5.3	9.0e-08	-0.58	1.00	0.00	FALSE
39	The Cancer Genome Atlas	Colon Adenocarcinoma	HIF1AN	0.07	0.03	blup	40	0.05	4.9e-04	-5.3	5.4	7.8e-08	0.05	0.03	0.84	FALSE
40	The Cancer Genome Atlas	Colon Adenocarcinoma	MRPL43	0.07	0.02	blup	52	0.00	1.7e-01	9.5	-8.6	6.4e-18	-0.83	0.01	0.84	FALSE
41	The Cancer Genome Atlas	Colon Adenocarcinoma	SEC31B	0.06	0.07	blup	51	0.08	2.9e-05	-4.6	5.2	2.6e-07	0.06	0.04	0.95	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MRPL43	0.03	0.02	blup	52	0.03	3.0e-04	-4.2	-6.2	6.4e-10	-0.71	0.09	0.55	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SEC31B	0.05	0.05	blup	51	0.05	1.3e-06	-5.3	5.3	1.4e-07	0.05	0.03	0.97	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEC31B	0.05	0.05	blup	51	0.05	8.9e-07	-5.3	5.2	2.2e-07	0.06	0.03	0.97	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEMA4G	0.04	0.01	blup	52	0.02	1.2e-03	8.2	8.4	5.3e-17	0.86	0.01	0.81	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SEC31B	0.14	0.10	lasso	7	0.10	1.6e-06	-5.4	5.3	9.1e-08	0.05	0.03	0.97	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	NDUFB8	0.02	0.01	blup	38	0.01	1.6e-02	-4.6	-5.3	1.2e-07	-0.06	0.03	0.60	FALSE
48	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEC31B	0.06	0.06	blup	51	0.06	1.1e-07	-5.2	5.4	5.5e-08	0.05	0.03	0.97	FALSE
49	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEMA4G	0.03	0.01	blup	52	0.01	4.2e-02	9.7	7.5	5.2e-14	0.85	0.00	0.90	FALSE
50	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SEC31B	0.15	0.14	lasso	12	0.15	8.5e-07	-5.2	5.2	1.6e-07	0.06	0.03	0.96	FALSE
51	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	FAM178A	0.14	0.08	lasso	2	0.08	5.9e-04	-7.2	-6.5	7.1e-11	-0.53	0.07	0.13	FALSE
52	The Cancer Genome Atlas	Thyroid Carcinoma	SEMA4G	0.07	0.08	blup	52	0.08	5.1e-08	-4.2	6.6	4.7e-11	0.77	0.04	0.96	FALSE