[Hub]/) : Traits : Arm predicted mass (right) :

chr10:101,548,177-103,428,898

Best TWAS P=1.06e-23 · Best GWAS P=3.04e-22 conditioned to 0.808

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SEC31B 0.13 0.21 lasso 3 0.20 4.1e-24 -5.3 5.3 1.1e-07 0.05 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous SEC31B 0.32 0.39 lasso 5 0.38 5.1e-33 -5.3 5.2 1.7e-07 0.06 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous RP11-179B2.2 0.15 0.08 lasso 6 0.08 3.2e-07 8.3 8.7 3.1e-18 0.92 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum RP11-179B2.2 0.13 0.02 lasso 3 0.03 6.5e-03 9.6 9.3 1.4e-20 0.98 0.01 0.99 FALSE
5 GTEx Artery Aorta RP11-179B2.2 0.16 0.11 lasso 2 0.09 7.6e-06 9.6 9.5 2.0e-21 0.97 0.00 0.99 FALSE
6 GTEx Artery Tibial RP11-179B2.2 0.11 0.09 lasso 4 0.08 8.8e-07 9.6 9.6 6.4e-22 0.95 0.00 0.99 FALSE
7 GTEx Brain Cerebellum RP11-179B2.2 0.37 0.21 lasso 4 0.20 1.4e-06 9.7 10.0 1.1e-23 0.94 0.00 0.99 TRUE
8 GTEx Brain Frontal Cortex BA9 RP11-179B2.2 0.22 0.15 lasso 2 0.11 7.2e-04 9.7 9.2 4.8e-20 0.97 0.01 0.96 FALSE
9 GTEx Breast Mammary Tissue RP11-179B2.2 0.11 0.09 lasso 2 0.07 1.8e-04 9.6 9.2 2.5e-20 0.97 0.01 0.99 FALSE
10 GTEx Breast Mammary Tissue (Male) SEC31B 0.13 0.08 lasso 4 0.10 3.0e-03 -5.3 5.3 1.4e-07 0.05 0.27 0.04 FALSE
11 GTEx Breast Mammary Tissue (Male) RP11-179B2.2 0.16 -0.01 enet 4 -0.01 7.1e-01 -9.0 9.1 7.2e-20 0.78 0.03 0.49 FALSE
12 GTEx Breast Mammary Tissue (Female) RP11-179B2.2 0.19 0.00 lasso 3 -0.01 5.1e-01 8.3 5.8 4.9e-09 0.66 0.03 0.42 FALSE
13 GTEx Colon Transverse SEC31B 0.28 0.12 lasso 3 0.09 3.3e-05 -5.3 5.3 8.7e-08 0.07 0.98 0.00 FALSE
14 GTEx Esophagus Gastroesophageal Junction SEC31B 0.15 0.21 lasso 4 0.20 8.0e-08 -5.3 5.3 1.4e-07 0.05 0.96 0.00 FALSE
15 GTEx Esophagus Mucosa SEC31B 0.14 0.18 lasso 4 0.17 2.0e-11 -5.3 5.3 1.4e-07 0.05 1.00 0.00 FALSE
16 GTEx Esophagus Mucosa HIF1AN 0.14 0.08 lasso 7 0.09 2.2e-06 -5.4 5.3 8.7e-08 0.09 0.98 0.00 FALSE
17 GTEx Esophagus Muscularis SEC31B 0.18 0.19 lasso 4 0.20 4.5e-12 -5.3 5.2 1.5e-07 0.05 1.00 0.00 FALSE
18 GTEx Esophagus Muscularis RP11-179B2.2 0.15 0.16 lasso 3 0.16 8.1e-10 9.7 9.7 3.0e-22 1.00 0.00 1.00 FALSE
19 GTEx Heart Left Ventricle RP11-179B2.2 0.15 0.18 enet 2 0.14 4.8e-08 9.7 9.7 5.0e-22 0.98 0.00 1.00 FALSE
20 GTEx Lung RP11-179B2.2 0.18 0.12 lasso 3 0.12 1.7e-09 9.7 9.3 1.1e-20 0.98 0.00 1.00 FALSE
21 GTEx Muscle Skeletal HIF1AN 0.05 0.06 lasso 1 0.05 1.6e-05 -5.3 -5.3 1.1e-07 -0.06 0.94 0.00 FALSE
22 GTEx Nerve Tibial RP11-179B2.2 0.15 0.08 lasso 2 0.12 6.4e-09 9.7 7.9 3.7e-15 0.91 0.00 1.00 FALSE
23 GTEx Pancreas SEC31B 0.24 0.19 lasso 5 0.17 9.9e-08 -5.3 5.2 2.4e-07 0.06 0.97 0.00 FALSE
24 GTEx Prostate SEC31B 0.18 0.14 lasso 2 0.12 6.7e-04 -5.2 5.2 1.5e-07 0.05 0.38 0.05 FALSE
25 GTEx Skin Not Sun Exposed Suprapubic SEC31B 0.15 0.16 lasso 4 0.15 8.3e-09 -5.3 5.3 1.4e-07 0.05 0.99 0.00 FALSE
26 GTEx Skin Not Sun Exposed Suprapubic HIF1AN 0.13 0.03 lasso 5 0.02 3.4e-02 -5.3 5.5 3.1e-08 0.04 0.26 0.03 TRUE
27 GTEx Skin Not Sun Exposed Suprapubic RP11-179B2.2 0.27 0.15 enet 36 0.15 2.0e-08 9.7 8.8 1.9e-18 0.74 0.00 1.00 FALSE
28 GTEx Skin Sun Exposed Lower leg HIF1AN 0.07 0.05 lasso 8 0.03 2.2e-03 -5.5 5.2 1.8e-07 0.06 0.93 0.00 FALSE
29 GTEx Skin Sun Exposed Lower leg RP11-179B2.2 0.12 0.09 lasso 2 0.08 1.7e-07 8.2 7.8 4.2e-15 0.89 0.04 0.96 FALSE
30 GTEx Spleen SEC31B 0.21 0.12 lasso 3 0.05 2.3e-02 -5.3 5.4 7.5e-08 0.06 0.28 0.09 FALSE
31 GTEx Testis SEC31B 0.11 0.11 lasso 5 0.08 2.5e-04 -5.3 5.3 1.1e-07 0.05 0.84 0.01 FALSE
32 GTEx Testis HIF1AN 0.12 0.08 lasso 3 0.06 1.6e-03 -5.4 5.5 3.1e-08 0.08 0.34 0.04 FALSE
33 GTEx Thyroid RP11-179B2.2 0.18 0.12 lasso 7 0.11 8.3e-09 8.3 8.8 1.1e-18 0.93 0.03 0.97 FALSE
34 GTEx Whole Blood HIF1AN 0.15 0.12 enet 7 0.12 8.7e-11 -5.4 5.4 6.8e-08 0.06 1.00 0.00 FALSE
35 METSIM Adipose MRPL43 0.05 0.04 bslmm 422 0.04 1.9e-06 -4.0 6.6 5.5e-11 0.48 0.94 0.02 FALSE
36 NTR Blood HIF1AN 0.02 0.03 lasso 2 0.02 1.4e-07 -5.3 5.3 9.0e-08 0.06 1.00 0.00 FALSE
37 NTR Blood SEC31B 0.03 0.03 lasso 4 0.03 1.1e-10 -5.3 5.3 1.4e-07 0.06 1.00 0.00 FALSE
38 ROSMAP Brain Pre-frontal Cortex MRPL43 0.10 0.08 bslmm 411 0.09 1.2e-11 -4.0 -5.3 9.0e-08 -0.58 1.00 0.00 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma HIF1AN 0.07 0.03 blup 40 0.05 4.9e-04 -5.3 5.4 7.8e-08 0.05 0.03 0.84 FALSE
40 The Cancer Genome Atlas Colon Adenocarcinoma MRPL43 0.07 0.02 blup 52 0.00 1.7e-01 9.5 -8.6 6.4e-18 -0.83 0.01 0.84 FALSE
41 The Cancer Genome Atlas Colon Adenocarcinoma SEC31B 0.06 0.07 blup 51 0.08 2.9e-05 -4.6 5.2 2.6e-07 0.06 0.04 0.95 FALSE
42 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MRPL43 0.03 0.02 blup 52 0.03 3.0e-04 -4.2 -6.2 6.4e-10 -0.71 0.09 0.55 FALSE
43 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SEC31B 0.05 0.05 blup 51 0.05 1.3e-06 -5.3 5.3 1.4e-07 0.05 0.03 0.97 FALSE
44 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SEC31B 0.05 0.05 blup 51 0.05 8.9e-07 -5.3 5.2 2.2e-07 0.06 0.03 0.97 FALSE
45 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SEMA4G 0.04 0.01 blup 52 0.02 1.2e-03 8.2 8.4 5.3e-17 0.86 0.01 0.81 FALSE
46 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SEC31B 0.14 0.10 lasso 7 0.10 1.6e-06 -5.4 5.3 9.1e-08 0.05 0.03 0.97 FALSE
47 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFB8 0.02 0.01 blup 38 0.01 1.6e-02 -4.6 -5.3 1.2e-07 -0.06 0.03 0.60 FALSE
48 The Cancer Genome Atlas Brain Lower Grade Glioma SEC31B 0.06 0.06 blup 51 0.06 1.1e-07 -5.2 5.4 5.5e-08 0.05 0.03 0.97 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma SEMA4G 0.03 0.01 blup 52 0.01 4.2e-02 9.7 7.5 5.2e-14 0.85 0.00 0.90 FALSE
50 The Cancer Genome Atlas Pancreatic Adenocarcinoma SEC31B 0.15 0.14 lasso 12 0.15 8.5e-07 -5.2 5.2 1.6e-07 0.06 0.03 0.96 FALSE
51 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma FAM178A 0.14 0.08 lasso 2 0.08 5.9e-04 -7.2 -6.5 7.1e-11 -0.53 0.07 0.13 FALSE
52 The Cancer Genome Atlas Thyroid Carcinoma SEMA4G 0.07 0.08 blup 52 0.08 5.1e-08 -4.2 6.6 4.7e-11 0.77 0.04 0.96 FALSE