Best TWAS P=6.3e-09 · Best GWAS P=1.25e-06 conditioned to 0.24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Liver | SYPL2 | 0.34 | 0.27 | lasso | 5 | 0.30 | 4.6e-09 | 4.2 | 5.3 | 1.4e-07 | 0.39 | 0.05 | 0.91 | FALSE |
| 2 | GTEx | Liver | ATXN7L2 | 0.39 | 0.04 | lasso | 12 | 0.21 | 1.3e-06 | 4.8 | 5.8 | 6.3e-09 | 0.69 | 0.04 | 0.82 | TRUE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | MYBPHL | 0.09 | 0.07 | blup | 46 | 0.06 | 5.7e-04 | 3.1 | 5.6 | 2.3e-08 | 0.57 | 0.01 | 0.51 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SORT1 | 0.04 | 0.01 | blup | 60 | 0.03 | 4.4e-03 | 4.6 | 5.5 | 5.1e-08 | 0.65 | 0.01 | 0.38 | FALSE |