[Hub]/) : Traits : Arm predicted mass (right) :

chr14:20,843,889-23,996,772

Best TWAS P=1.5e-10 · Best GWAS P=3.62e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARHGEF40 0.34 0.32 enet 17 0.31 1.5e-17 -5.6 -5.4 5.6e-08 -0.07 0.27 0.73 TRUE
2 GTEx Cells Transformed fibroblasts TOX4 0.19 0.06 lasso 7 0.05 6.6e-05 -6.5 -5.7 9.7e-09 0.92 0.00 0.99 FALSE
3 GTEx Testis TOX4 0.31 0.00 enet 24 0.04 6.8e-03 -6.6 -6.2 5.7e-10 0.65 0.02 0.82 FALSE
4 YFS Blood MRPL52 0.44 0.22 enet 27 0.28 2.2e-93 -4.6 6.1 9.1e-10 -0.04 0.97 0.03 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma METTL3 0.03 0.04 lasso 1 0.04 3.1e-08 -6.2 -6.2 4.3e-10 0.95 0.02 0.98 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma METTL3 0.04 0.04 lasso 2 0.04 2.5e-05 -6.4 -6.4 1.5e-10 0.96 0.01 0.99 TRUE
7 The Cancer Genome Atlas Testicular Germ Cell Tumors METTL3 0.17 0.03 lasso 2 0.04 1.5e-02 -6.4 -6.2 4.2e-10 0.92 0.01 0.82 FALSE
8 The Cancer Genome Atlas Testicular Germ Cell Tumors RAB2B 0.12 0.04 blup 52 0.07 2.1e-03 -4.1 -5.7 1.3e-08 0.73 0.01 0.45 FALSE