[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr17:45,228,469-47,688,526

Best TWAS P=1.12e-12 · Best GWAS P=1.93e-09 conditioned to 8.19e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TTLL6 0.23 0.12 bslmm 418 0.15 1.7e-17 1.1 -6.0 2.4e-09 -0.09 0.60 0.39 FALSE
2 GTEx Brain Nucleus accumbens basal ganglia RP11-6N17.9 0.47 0.05 lasso 17 0.11 8.3e-04 5.1 -5.4 6.6e-08 -0.07 0.04 0.76 TRUE
3 GTEx Cells EBV-transformed lymphocytes HOXB3 0.28 0.00 lasso 7 0.00 5.0e-01 -3.9 -6.1 9.4e-10 0.17 0.04 0.18 FALSE
4 GTEx Liver SCRN2 0.32 0.05 enet 14 0.11 5.5e-04 -4.8 5.8 8.2e-09 -0.29 0.09 0.60 TRUE
5 GTEx Testis RP11-6N17.4 0.14 0.02 lasso 10 0.02 4.8e-02 5.5 5.3 1.2e-07 -0.06 0.04 0.92 FALSE
6 METSIM Adipose UBE2Z 0.06 0.06 enet 16 0.04 3.2e-06 5.1 5.1 2.9e-07 -0.04 0.15 0.85 FALSE
7 YFS Blood UBE2Z 0.06 0.03 enet 19 0.06 1.5e-18 2.3 6.4 1.3e-10 -0.06 0.12 0.88 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ATP5G1 0.04 0.01 enet 6 0.03 5.4e-05 5.1 6.4 1.7e-10 -0.17 0.07 0.73 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CALCOCO2 0.04 0.03 blup 50 0.02 1.6e-03 -3.9 7.1 1.1e-12 -0.04 0.02 0.21 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma CALCOCO2 0.08 0.03 blup 50 0.07 1.4e-07 -3.9 6.5 9.2e-11 -0.19 0.05 0.94 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma CBX1 0.03 0.04 lasso 4 0.04 3.7e-05 5.6 -5.5 2.8e-08 0.05 0.02 0.97 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma MRPL10 0.07 0.00 blup 59 0.02 8.7e-03 -4.8 -5.4 7.4e-08 0.27 0.00 0.48 FALSE