[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr2:197,560,575-201,571,143

Best TWAS P=5.08e-15 · Best GWAS P=5.38e-17 conditioned to 8.88e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PLCL1	0.06	0.01	blup	397	0.02	4.9e-04	-0.36	-5.7	1.5e-08	0.35	0.08	0.42	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SF3B1	0.06	0.07	enet	10	0.07	2.5e-09	-5.51	-5.6	2.8e-08	0.49	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	TYW5	0.08	0.14	lasso	8	0.13	2.2e-15	-5.18	5.3	8.6e-08	-0.05	0.01	0.99	FALSE
4	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	-7.09	-6.9	5.0e-12	0.86	0.41	0.59	FALSE
5	GTEx	Brain Caudate basal ganglia	TYW5	0.23	0.11	lasso	3	0.11	5.4e-04	-4.42	5.3	1.1e-07	-0.03	0.04	0.60	FALSE
6	GTEx	Brain Hippocampus	FTCDNL1	0.35	0.24	enet	24	0.26	9.0e-07	-3.88	-6.1	1.2e-09	-0.10	0.21	0.45	TRUE
7	GTEx	Brain Nucleus accumbens basal ganglia	C2orf47	0.25	0.01	lasso	3	0.00	2.8e-01	4.49	-5.2	1.6e-07	0.04	0.06	0.37	FALSE
8	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	-5.54	-6.6	5.4e-11	0.61	0.17	0.68	FALSE
9	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	-5.46	-6.5	7.8e-11	0.65	0.05	0.11	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	HSPD1	0.15	0.04	lasso	7	0.04	2.0e-02	-3.72	5.1	2.7e-07	-0.64	0.12	0.53	FALSE
11	GTEx	Esophagus Mucosa	SF3B1	0.04	0.02	lasso	4	0.01	5.7e-02	-5.37	-5.2	1.7e-07	0.48	0.32	0.05	FALSE
12	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	-7.70	-7.7	1.9e-14	0.86	0.16	0.84	FALSE
13	GTEx	Nerve Tibial	SF3B1	0.06	0.09	lasso	8	0.08	3.3e-06	-5.46	-5.4	5.4e-08	0.54	0.97	0.03	FALSE
14	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	-7.95	7.8	5.1e-15	-0.86	0.10	0.89	TRUE
15	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	-7.92	-7.6	3.8e-14	0.84	0.10	0.31	FALSE
16	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	-7.93	7.5	5.1e-14	-0.82	0.07	0.33	FALSE
17	GTEx	Testis	SF3B1	0.10	0.07	enet	17	0.08	2.6e-04	-5.51	-5.7	1.4e-08	0.55	0.53	0.40	FALSE
18	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	-5.20	-6.8	1.3e-11	0.72	0.12	0.78	FALSE
19	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	-7.70	-7.4	1.7e-13	0.76	0.21	0.48	FALSE
20	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	-7.90	-6.7	2.2e-11	0.80	0.09	0.73	FALSE
21	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	-7.22	-7.5	6.9e-14	0.92	0.13	0.87	FALSE
22	ROSMAP	Brain Pre-frontal Cortex	TYW5	0.11	0.12	lasso	5	0.11	5.5e-14	-5.18	5.4	5.6e-08	-0.04	0.01	0.99	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	C2orf69	0.07	0.04	enet	13	0.06	3.6e-08	-4.96	5.2	2.2e-07	-0.05	0.04	0.96	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	MARS2	0.05	0.03	enet	14	0.05	2.2e-07	4.30	5.5	5.1e-08	-0.75	0.20	0.79	FALSE
25	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	-7.25	-6.0	1.4e-09	0.83	0.89	0.11	FALSE
26	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	2.57	-6.6	5.4e-11	0.65	0.05	0.38	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf60	0.03	0.03	blup	44	0.03	1.8e-04	-5.19	5.5	4.3e-08	-0.05	0.01	0.97	TRUE
28	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf60	0.04	0.05	lasso	5	0.03	2.1e-03	-5.24	5.2	1.6e-07	-0.04	0.01	0.90	FALSE
29	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	-5.48	-7.0	1.7e-12	0.70	0.04	0.40	FALSE