[Hub]/) : Traits : Arm fat percentage (left) :

chr11:63,295,034-67,070,766

Best TWAS P=9.44e-12 · Best GWAS P=2.63e-09 conditioned to 0.0929

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FIBP 0.08 0.11 enet 20 0.12 8.1e-14 5.0 5.7 1.1e-08 -0.34 0.24 0.76 FALSE
2 GTEx Adipose Subcutaneous CTSW 0.30 0.18 lasso 6 0.16 3.9e-13 5.0 -5.3 1.1e-07 0.13 0.32 0.67 FALSE
3 GTEx Adipose Visceral Omentum TRPT1 0.16 0.05 lasso 5 0.04 3.0e-03 -4.8 -5.7 9.3e-09 0.04 0.09 0.38 FALSE
4 GTEx Adrenal Gland CTSW 0.13 0.08 lasso 12 0.06 3.0e-03 5.6 -6.0 2.3e-09 0.22 0.12 0.68 FALSE
5 GTEx Breast Mammary Tissue CTSW 0.25 0.19 lasso 8 0.16 1.3e-08 5.1 -5.2 2.2e-07 0.13 0.32 0.68 FALSE
6 GTEx Breast Mammary Tissue (Male) NEAT1 0.27 0.01 enet 29 0.03 6.3e-02 4.6 5.2 2.6e-07 -0.16 0.03 0.34 FALSE
7 GTEx Cells EBV-transformed lymphocytes CCS 0.21 0.24 enet 11 0.21 2.0e-07 -5.2 5.2 2.0e-07 0.04 0.18 0.81 FALSE
8 GTEx Cells Transformed fibroblasts EFEMP2 0.06 0.06 lasso 3 0.07 7.8e-06 4.6 5.2 1.8e-07 -0.23 0.10 0.88 FALSE
9 GTEx Colon Transverse CTSW 0.37 0.27 lasso 8 0.26 1.5e-12 5.0 -5.3 9.8e-08 0.17 0.28 0.72 FALSE
10 GTEx Esophagus Mucosa PLCB3 0.28 0.24 lasso 6 0.23 1.1e-15 -5.9 5.4 7.9e-08 -0.03 0.00 1.00 FALSE
11 GTEx Esophagus Muscularis TRPT1 0.20 0.12 enet 18 0.15 2.3e-09 -4.8 -5.4 5.4e-08 0.04 0.19 0.81 FALSE
12 GTEx Esophagus Muscularis CTD-3074O7.5 0.22 0.02 enet 17 0.09 3.7e-06 -4.2 6.8 9.4e-12 -0.50 0.29 0.47 TRUE
13 GTEx Heart Atrial Appendage KLC2 0.10 0.04 lasso 8 0.09 1.1e-04 3.9 -5.2 1.7e-07 0.56 0.30 0.36 FALSE
14 GTEx Heart Left Ventricle FIBP 0.12 0.09 lasso 3 0.07 9.8e-05 5.0 5.4 8.3e-08 -0.17 0.27 0.69 FALSE
15 GTEx Liver CTSW 0.27 0.03 lasso 13 0.02 1.0e-01 5.0 -5.2 1.5e-07 0.23 0.06 0.18 FALSE
16 GTEx Nerve Tibial TRPT1 0.14 0.03 lasso 6 0.07 1.8e-05 -5.0 -5.3 1.4e-07 0.03 0.08 0.88 FALSE
17 GTEx Nerve Tibial CTSW 0.22 0.19 lasso 7 0.18 1.3e-12 5.0 -5.2 2.2e-07 0.13 0.33 0.67 FALSE
18 GTEx Skin Not Sun Exposed Suprapubic CTSW 0.27 0.22 lasso 12 0.22 1.9e-12 5.1 -5.5 3.4e-08 0.17 0.27 0.73 FALSE
19 GTEx Skin Sun Exposed Lower leg CTSW 0.19 0.19 lasso 6 0.18 1.1e-14 5.0 -5.2 2.2e-07 0.13 0.33 0.67 FALSE
20 GTEx Thyroid CTSW 0.18 0.22 lasso 2 0.21 4.6e-16 5.0 -5.2 1.5e-07 0.14 0.33 0.67 FALSE
21 NTR Blood CCS 0.03 0.04 lasso 2 0.04 1.2e-11 -5.2 5.2 1.9e-07 0.03 0.19 0.81 FALSE
22 ROSMAP Brain Pre-frontal Cortex CTSW 0.06 0.03 bslmm 328 0.03 3.6e-05 5.3 -5.6 1.8e-08 0.12 0.24 0.61 FALSE
23 ROSMAP Brain Pre-frontal Cortex CCS 0.08 0.04 lasso 9 0.06 8.9e-08 -5.2 5.6 2.5e-08 -0.05 0.21 0.79 FALSE
24 ROSMAP Brain Pre-frontal Cortex CTSF 0.07 0.08 blup 244 0.07 1.6e-09 -4.2 -5.3 1.5e-07 0.22 0.96 0.04 FALSE
25 ROSMAP Brain Pre-frontal Cortex KCNK4 0.14 0.12 bslmm 334 0.11 3.0e-14 -5.5 -5.7 1.1e-08 0.06 0.00 1.00 FALSE
26 ROSMAP Brain Pre-frontal Cortex TEX40 0.25 0.23 lasso 3 0.23 2.5e-29 -5.9 5.8 6.0e-09 -0.05 0.00 1.00 FALSE
27 ROSMAP Brain Pre-frontal Cortex RP11-783K16.10 0.07 0.05 lasso 6 0.06 9.6e-08 -5.9 5.7 1.3e-08 -0.05 0.00 1.00 FALSE
28 YFS Blood PRDX5 0.51 0.40 lasso 9 0.43 4.0e-157 -5.5 -5.4 5.6e-08 0.04 0.02 0.98 FALSE
29 The Cancer Genome Atlas Breast Invasive Carcinoma CTSW 0.25 0.39 blup 44 0.41 7.3e-91 5.1 -5.5 4.5e-08 0.17 0.05 0.95 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma SNX32 0.15 0.17 blup 60 0.17 2.9e-34 5.3 5.3 9.4e-08 -0.16 0.02 0.98 FALSE
31 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma CTSW 0.21 0.16 blup 44 0.17 7.5e-09 5.3 -5.2 1.8e-07 0.10 0.04 0.96 FALSE
32 The Cancer Genome Atlas Colon Adenocarcinoma CTSW 0.40 0.34 enet 14 0.36 4.3e-22 5.0 -5.1 2.9e-07 0.09 0.04 0.96 FALSE
33 The Cancer Genome Atlas Glioblastoma Multiforme CTSW 0.16 0.18 enet 16 0.19 2.3e-06 5.6 -6.0 2.6e-09 0.23 0.01 0.98 FALSE
34 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C11orf20 0.06 0.03 lasso 3 0.02 7.2e-04 -5.7 5.8 7.3e-09 -0.04 0.00 0.98 FALSE
35 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CTSW 0.31 0.32 lasso 4 0.34 1.8e-39 5.1 -5.2 1.9e-07 0.13 0.05 0.95 FALSE
36 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C11orf20 0.07 0.07 lasso 4 0.07 6.4e-08 -5.9 5.9 4.7e-09 -0.05 0.00 1.00 FALSE
37 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC87 0.03 0.02 blup 34 0.02 2.0e-03 -4.9 -5.6 1.7e-08 0.18 0.02 0.50 FALSE
38 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CTSW 0.32 0.26 lasso 1 0.26 4.3e-15 5.3 -5.3 1.2e-07 0.12 0.04 0.96 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma CTSF 0.05 0.04 blup 35 0.04 1.2e-05 -4.2 -5.5 4.5e-08 0.13 0.18 0.72 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma CTSW 0.13 0.14 blup 44 0.14 7.0e-16 5.1 -5.3 1.2e-07 0.11 0.05 0.95 FALSE
41 The Cancer Genome Atlas Brain Lower Grade Glioma FIBP 0.04 0.04 lasso 3 0.04 1.2e-05 5.3 5.2 1.9e-07 -0.13 0.04 0.96 FALSE
42 The Cancer Genome Atlas Liver Hepatocellular Carcinoma CTSW 0.63 0.41 lasso 8 0.42 1.2e-21 5.3 -5.2 1.5e-07 0.12 0.04 0.96 FALSE
43 The Cancer Genome Atlas Lung Adenocarcinoma CTSW 0.23 0.29 lasso 7 0.29 1.0e-33 5.1 -5.1 2.8e-07 0.13 0.04 0.95 FALSE
44 The Cancer Genome Atlas Lung Adenocarcinoma SNX32 0.14 0.09 blup 60 0.13 8.8e-15 5.3 5.3 1.5e-07 -0.16 0.04 0.96 FALSE
45 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C11orf20 0.04 0.03 lasso 2 0.03 4.2e-04 -5.5 5.5 3.7e-08 -0.05 0.00 0.99 FALSE
46 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CTSW 0.25 0.34 enet 14 0.34 4.1e-40 5.1 -5.3 1.4e-07 0.14 0.05 0.95 FALSE
47 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CTSW 0.20 0.23 lasso 9 0.23 1.5e-15 5.1 -5.2 2.5e-07 0.13 0.05 0.95 FALSE
48 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma VEGFB 0.04 0.04 blup 47 0.02 8.9e-03 -4.9 6.0 2.0e-09 -0.03 0.03 0.48 TRUE
49 The Cancer Genome Atlas Pancreatic Adenocarcinoma CTSW 0.30 0.23 lasso 11 0.24 1.7e-10 5.1 -5.1 2.9e-07 0.14 0.05 0.95 FALSE
50 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SNX32 0.30 0.19 lasso 1 0.14 3.9e-06 5.3 5.3 1.4e-07 -0.12 0.03 0.96 FALSE
51 The Cancer Genome Atlas Prostate Adenocarcinoma C11orf20 0.07 0.03 enet 10 0.05 3.8e-06 -5.9 5.3 1.4e-07 0.00 0.00 0.99 FALSE
52 The Cancer Genome Atlas Soft Tissue Sarcoma SNX32 0.08 0.08 lasso 2 0.10 1.5e-06 4.6 5.4 5.5e-08 -0.21 0.04 0.95 FALSE
53 The Cancer Genome Atlas Stomach Adenocarcinoma SNX32 0.12 0.13 blup 60 0.13 1.2e-09 5.1 6.3 3.8e-10 -0.16 0.05 0.95 TRUE
54 The Cancer Genome Atlas Testicular Germ Cell Tumors CTSW 0.26 0.29 lasso 9 0.27 4.7e-10 5.1 -5.4 8.3e-08 0.14 0.05 0.95 FALSE
55 The Cancer Genome Atlas Thyroid Carcinoma PRDX5 0.05 0.04 lasso 3 0.02 1.6e-03 -5.9 5.9 4.3e-09 -0.05 0.00 0.95 FALSE
56 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma CTSW 0.24 0.21 enet 21 0.24 2.9e-07 5.1 -5.3 1.1e-07 0.17 0.05 0.95 FALSE