[Hub]/) : Traits : Arm fat percentage (left) :

chr11:46,064,974-48,783,497

Best TWAS P=7.68e-44 · Best GWAS P=1.3e-42 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM180B 0.07 0.08 lasso 3 0.08 9.1e-10 13.53 13.0 2.2e-38 0.95 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex MADD 0.32 0.17 bslmm 315 0.18 1.4e-21 -6.56 6.9 5.0e-12 0.19 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex MTCH2 0.03 0.00 bslmm 299 0.00 1.1e-01 0.79 9.5 2.7e-21 0.68 0.07 0.54 FALSE
4 GTEx Adipose Subcutaneous ACP2 0.08 0.03 enet 18 0.03 3.5e-03 -4.55 9.3 1.2e-20 0.73 0.08 0.78 FALSE
5 GTEx Adipose Subcutaneous C1QTNF4 0.16 0.22 lasso 4 0.22 2.5e-18 13.68 -13.3 1.8e-40 -0.98 0.00 1.00 FALSE
6 GTEx Adipose Visceral Omentum ACP2 0.08 0.05 lasso 5 0.05 1.4e-03 -5.08 5.2 2.3e-07 0.31 0.41 0.03 FALSE
7 GTEx Artery Aorta MADD 0.09 0.03 enet 22 0.04 1.9e-03 -8.99 5.6 2.0e-08 0.12 0.14 0.04 FALSE
8 GTEx Artery Aorta C1QTNF4 0.09 0.10 lasso 1 0.08 3.2e-05 13.53 -13.5 1.0e-41 -1.00 0.00 0.99 FALSE
9 GTEx Brain Cerebellar Hemisphere MADD 0.44 0.14 lasso 7 0.21 4.0e-06 -4.55 8.1 3.9e-16 0.50 0.33 0.19 FALSE
10 GTEx Brain Cerebellar Hemisphere ACP2 0.29 0.05 enet 16 0.12 5.9e-04 -4.10 5.8 9.0e-09 0.44 0.09 0.10 FALSE
11 GTEx Brain Cerebellar Hemisphere RP11-750H9.5 0.17 0.25 lasso 6 0.21 3.5e-06 -6.71 6.7 1.9e-11 0.29 0.43 0.06 FALSE
12 GTEx Brain Cerebellum MADD 0.21 0.00 enet 13 0.11 3.3e-04 -5.08 10.4 1.5e-25 0.63 0.07 0.68 FALSE
13 GTEx Brain Cortex MTCH2 0.21 0.19 lasso 6 0.16 4.0e-05 11.89 10.6 2.8e-26 0.79 0.35 0.18 FALSE
14 GTEx Brain Cortex C1QTNF4 0.26 0.04 lasso 8 0.02 1.2e-01 -11.64 -12.1 1.4e-33 -0.80 0.02 0.58 FALSE
15 GTEx Brain Putamen basal ganglia CKAP5 0.25 0.07 lasso 3 0.14 4.4e-04 -4.87 -5.5 4.8e-08 -0.44 0.05 0.27 FALSE
16 GTEx Breast Mammary Tissue C1QTNF4 0.10 0.06 lasso 2 0.03 8.5e-03 11.09 -10.8 3.0e-27 -0.82 0.11 0.67 FALSE
17 GTEx Breast Mammary Tissue (Female) MADD 0.13 0.04 lasso 3 0.05 1.3e-02 11.05 11.5 7.5e-31 0.81 0.05 0.32 TRUE
18 GTEx Cells Transformed fibroblasts FNBP4 0.11 0.05 lasso 8 0.08 1.6e-06 -11.71 12.9 3.3e-38 0.88 0.04 0.96 FALSE
19 GTEx Cells Transformed fibroblasts MADD 0.19 0.00 enet 17 0.09 3.3e-07 -5.31 7.8 5.8e-15 0.30 0.53 0.04 FALSE
20 GTEx Cells Transformed fibroblasts PSMC3 0.07 0.00 enet 13 0.02 2.3e-02 -4.18 10.2 1.2e-24 0.83 0.03 0.77 FALSE
21 GTEx Cells Transformed fibroblasts C1QTNF4 0.13 0.11 enet 19 0.12 5.2e-09 12.18 -11.4 6.9e-30 -0.84 0.03 0.97 FALSE
22 GTEx Cells Transformed fibroblasts NDUFS3 0.08 0.01 lasso 2 0.01 3.3e-02 13.68 -13.3 2.5e-40 -0.98 0.00 0.98 FALSE
23 GTEx Colon Transverse C1QTNF4 0.07 0.02 lasso 6 0.03 2.0e-02 13.68 -13.2 7.3e-40 -0.96 0.01 0.96 FALSE
24 GTEx Esophagus Gastroesophageal Junction NUP160 0.18 0.02 enet 18 0.11 7.1e-05 -1.44 5.2 2.4e-07 0.29 0.27 0.05 FALSE
25 GTEx Esophagus Mucosa MADD 0.27 0.04 enet 18 0.12 4.1e-08 -5.05 8.6 5.6e-18 0.40 0.26 0.08 FALSE
26 GTEx Esophagus Mucosa ACP2 0.07 0.04 enet 11 0.04 6.2e-04 -4.97 5.1 2.9e-07 0.33 0.78 0.05 FALSE
27 GTEx Esophagus Mucosa C11orf49 0.19 0.05 enet 21 0.12 3.2e-08 -4.92 -5.7 9.3e-09 -0.29 0.79 0.01 FALSE
28 GTEx Esophagus Mucosa C1QTNF4 0.10 0.11 lasso 1 0.10 5.0e-07 13.53 -13.5 1.0e-41 -1.00 0.00 1.00 FALSE
29 GTEx Esophagus Muscularis MTCH2 0.09 0.04 lasso 6 0.02 1.8e-02 12.18 11.9 1.6e-32 0.78 0.26 0.53 FALSE
30 GTEx Esophagus Muscularis MADD 0.13 0.07 enet 8 0.11 2.0e-07 -6.56 6.1 8.6e-10 0.17 0.73 0.01 FALSE
31 GTEx Esophagus Muscularis C1QTNF4 0.10 0.05 enet 23 0.06 1.4e-04 13.68 -12.8 1.9e-37 -0.93 0.01 0.99 FALSE
32 GTEx Heart Atrial Appendage ACP2 0.10 0.12 enet 7 0.10 2.7e-05 -5.52 7.2 8.7e-13 0.49 0.32 0.07 FALSE
33 GTEx Heart Atrial Appendage C1QTNF4 0.26 0.14 lasso 9 0.17 3.9e-08 13.53 -13.2 4.5e-40 -0.95 0.02 0.98 FALSE
34 GTEx Heart Left Ventricle MADD 0.14 0.01 enet 17 0.05 7.0e-04 -4.85 10.2 1.7e-24 0.70 0.02 0.95 TRUE
35 GTEx Heart Left Ventricle C1QTNF4 0.10 0.11 lasso 1 0.09 1.1e-05 13.53 -13.5 1.0e-41 -1.00 0.00 0.99 FALSE
36 GTEx Liver PSMC3 0.15 0.09 lasso 4 0.07 5.9e-03 7.23 8.0 1.0e-15 0.59 0.09 0.10 FALSE
37 GTEx Liver C1QTNF4 0.25 0.14 enet 16 0.20 2.3e-06 13.53 -12.8 1.1e-37 -0.84 0.02 0.97 TRUE
38 GTEx Lung ACP2 0.04 0.03 lasso 2 0.04 4.3e-04 -4.67 5.2 1.7e-07 0.39 0.55 0.02 FALSE
39 GTEx Lung C1QTNF4 0.18 0.15 lasso 6 0.13 3.2e-10 11.03 -12.3 8.7e-35 -0.91 0.09 0.91 FALSE
40 GTEx Muscle Skeletal MTCH2 0.05 0.03 enet 15 0.04 1.5e-04 11.38 12.1 1.2e-33 0.84 0.05 0.94 FALSE
41 GTEx Muscle Skeletal C1QTNF4 0.09 0.14 lasso 3 0.13 9.9e-13 13.53 -13.5 2.4e-41 -0.98 0.00 1.00 FALSE
42 GTEx Nerve Tibial NR1H3 0.10 0.00 enet 24 0.08 4.7e-06 -1.51 -9.0 3.0e-19 -0.52 0.01 0.82 FALSE
43 GTEx Nerve Tibial PTPRJ 0.05 0.03 enet 13 0.03 2.7e-03 -3.89 -6.5 8.0e-11 -0.50 0.19 0.08 FALSE
44 GTEx Nerve Tibial CELF1 0.08 0.02 enet 15 0.06 4.3e-05 -10.53 7.0 3.1e-12 0.40 0.21 0.04 FALSE
45 GTEx Nerve Tibial SLC39A13 0.07 0.01 enet 14 0.02 7.6e-03 11.08 7.6 2.8e-14 0.70 0.13 0.34 FALSE
46 GTEx Nerve Tibial C1QTNF4 0.20 0.23 enet 12 0.23 1.7e-16 13.53 -12.7 4.1e-37 -0.96 0.00 1.00 FALSE
47 GTEx Pituitary MADD 0.42 0.32 lasso 6 0.39 8.9e-11 -5.93 10.4 2.1e-25 0.60 0.25 0.63 FALSE
48 GTEx Skin Not Sun Exposed Suprapubic LRP4 0.13 0.00 lasso 7 0.02 3.5e-02 -0.79 -6.1 1.2e-09 -0.60 0.04 0.74 FALSE
49 GTEx Skin Not Sun Exposed Suprapubic C1QTNF4 0.32 0.18 enet 33 0.20 5.2e-11 13.53 -12.1 1.9e-33 -0.90 0.00 1.00 FALSE
50 GTEx Skin Sun Exposed Lower leg PSMC3 0.20 0.05 lasso 7 0.10 1.2e-08 -4.18 7.1 1.3e-12 0.68 0.69 0.29 FALSE
51 GTEx Skin Sun Exposed Lower leg C1QTNF4 0.25 0.22 lasso 12 0.23 4.2e-19 13.53 -13.4 3.6e-41 -0.95 0.00 1.00 FALSE
52 GTEx Spleen C1QTNF4 0.31 0.28 enet 29 0.34 1.8e-09 11.89 -13.2 8.8e-40 -0.89 0.08 0.92 FALSE
53 GTEx Testis MTCH2 0.17 0.16 lasso 3 0.16 1.0e-07 11.09 11.1 1.1e-28 0.83 0.52 0.48 FALSE
54 GTEx Testis C1QTNF4 0.14 0.12 lasso 4 0.11 1.6e-05 -11.75 -11.8 5.8e-32 -0.73 0.28 0.67 FALSE
55 GTEx Thyroid MADD 0.11 0.00 enet 13 0.01 6.1e-02 -3.91 6.6 3.3e-11 0.25 0.06 0.04 FALSE
56 GTEx Thyroid ACP2 0.19 0.14 lasso 4 0.12 3.0e-09 -5.08 5.6 1.9e-08 0.34 1.00 0.00 FALSE
57 GTEx Whole Blood C1QTNF4 0.09 0.05 lasso 3 0.03 1.4e-03 11.91 -12.0 3.7e-33 -0.86 0.18 0.72 FALSE
58 METSIM Adipose ACP2 0.05 0.04 blup 302 0.06 1.7e-09 11.09 8.0 1.9e-15 0.67 0.36 0.64 FALSE
59 METSIM Adipose C1QTNF4 0.24 0.31 lasso 7 0.31 1.2e-46 12.03 -11.8 4.3e-32 -0.86 1.00 0.00 FALSE
60 METSIM Adipose MYBPC3 0.11 0.10 enet 26 0.11 1.0e-15 11.09 -10.2 2.2e-24 -0.81 0.32 0.68 TRUE
61 METSIM Adipose PSMC3 0.06 0.03 enet 28 0.04 2.3e-06 5.27 8.7 3.1e-18 0.79 0.03 0.96 FALSE
62 NTR Blood ACP2 0.01 0.00 enet 7 0.01 2.5e-03 -4.97 6.9 4.5e-12 0.44 0.43 0.11 FALSE
63 NTR Blood MTCH2 0.02 0.04 lasso 1 0.04 1.3e-11 12.18 -12.2 3.8e-34 -0.88 0.89 0.11 FALSE
64 ROSMAP Brain Pre-frontal Cortex MTCH2 0.35 0.40 enet 9 0.40 4.7e-56 12.03 12.5 7.7e-36 0.91 1.00 0.00 FALSE
65 ROSMAP Brain Pre-frontal Cortex FNBP4 0.04 0.04 lasso 3 0.04 8.2e-06 -11.74 12.2 2.4e-34 0.69 0.95 0.05 FALSE
66 ROSMAP Brain Pre-frontal Cortex MADD 0.33 0.16 enet 23 0.23 1.9e-29 -6.56 5.2 2.0e-07 0.08 1.00 0.00 FALSE
67 ROSMAP Brain Pre-frontal Cortex ACP2 0.03 0.00 blup 295 0.02 1.5e-03 11.03 9.2 4.8e-20 0.72 0.06 0.87 FALSE
68 ROSMAP Brain Pre-frontal Cortex PSMC3 0.15 0.08 bslmm 285 0.10 5.1e-13 -2.98 7.2 7.0e-13 0.68 0.40 0.60 FALSE
69 ROSMAP Brain Pre-frontal Cortex C1QTNF4 0.05 0.06 blup 281 0.06 1.7e-08 11.07 -10.9 1.5e-27 -0.86 0.11 0.89 FALSE
70 YFS Blood DDB2 0.02 0.00 bslmm 306 0.01 1.9e-04 -4.86 5.3 1.2e-07 0.20 0.24 0.05 FALSE
71 YFS Blood FNBP4 0.02 0.01 bslmm 301 0.01 8.9e-05 -9.68 11.2 3.3e-29 0.78 0.03 0.95 FALSE
72 YFS Blood NR1H3 0.34 0.15 enet 66 0.24 3.1e-76 -4.65 7.5 4.7e-14 0.56 1.00 0.00 FALSE
73 YFS Blood NUP160 0.02 0.01 blup 290 0.01 1.7e-04 11.93 7.0 2.6e-12 0.65 0.24 0.60 FALSE
74 YFS Blood PSMC3 0.02 0.01 blup 289 0.01 2.8e-05 13.68 10.4 3.1e-25 0.84 0.00 0.99 FALSE
75 YFS Blood PTPMT1 0.03 0.01 lasso 5 0.01 3.2e-04 -11.82 -10.2 1.5e-24 -0.67 0.27 0.61 FALSE
76 YFS Blood SPI1 0.65 0.18 enet 75 0.27 1.6e-87 11.00 -8.2 3.4e-16 -0.62 1.00 0.00 FALSE
77 The Cancer Genome Atlas Bladder Urothelial Carcinoma C1QTNF4 0.06 0.07 lasso 2 0.06 4.9e-06 12.11 -12.8 1.0e-37 -0.93 0.01 0.99 FALSE
78 The Cancer Genome Atlas Breast Invasive Carcinoma ACP2 0.02 0.01 blup 44 0.02 2.7e-04 -5.08 7.8 5.5e-15 0.50 0.04 0.21 FALSE
79 The Cancer Genome Atlas Breast Invasive Carcinoma C1QTNF4 0.02 0.01 lasso 5 0.02 2.1e-04 -2.46 -8.4 6.5e-17 -0.74 0.01 0.83 FALSE
80 The Cancer Genome Atlas Breast Invasive Carcinoma MADD 0.11 0.03 enet 14 0.06 1.4e-11 -6.56 11.1 2.2e-28 0.56 0.04 0.96 FALSE
81 The Cancer Genome Atlas Breast Invasive Carcinoma MYBPC3 0.02 0.01 blup 43 0.01 3.4e-03 11.03 -10.1 4.1e-24 -0.74 0.01 0.97 FALSE
82 The Cancer Genome Atlas Breast Invasive Carcinoma NUP160 0.03 0.01 blup 44 0.01 1.9e-03 11.36 7.2 7.3e-13 0.58 0.01 0.51 FALSE
83 The Cancer Genome Atlas Colon Adenocarcinoma C1QTNF4 0.12 0.12 lasso 1 0.12 1.6e-07 13.53 -13.5 1.0e-41 -1.00 0.00 1.00 FALSE
84 The Cancer Genome Atlas Colon Adenocarcinoma KBTBD4 0.14 0.01 blup 13 0.02 1.6e-02 -11.85 11.0 5.9e-28 0.90 0.00 0.53 FALSE
85 The Cancer Genome Atlas Colon Adenocarcinoma NUP160 0.05 0.05 blup 44 0.05 7.7e-04 -11.75 12.7 3.6e-37 0.82 0.04 0.60 FALSE
86 The Cancer Genome Atlas Colon Adenocarcinoma PSMC3 0.09 0.05 blup 39 0.05 1.0e-03 -6.71 9.2 5.6e-20 0.55 0.02 0.82 FALSE
87 The Cancer Genome Atlas Esophageal Carcinoma C1QTNF4 0.39 0.33 blup 15 0.35 6.1e-12 13.53 -13.3 1.6e-40 -0.98 0.00 1.00 FALSE
88 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C1QTNF4 0.06 0.08 lasso 3 0.08 7.5e-09 12.03 -12.1 1.2e-33 -0.88 0.04 0.96 FALSE
89 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FNBP4 0.10 0.03 blup 45 0.05 7.7e-06 11.93 7.1 1.4e-12 0.51 0.01 0.98 FALSE
90 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MYBPC3 0.05 0.03 blup 43 0.04 6.0e-05 8.54 -9.5 2.9e-21 -0.71 0.01 0.98 FALSE
91 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NUP160 0.08 0.03 blup 42 0.04 6.7e-05 11.94 9.7 2.5e-22 0.71 0.01 0.96 FALSE
92 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C1QTNF4 0.12 0.14 enet 4 0.16 6.5e-18 12.03 -13.0 1.1e-38 -0.95 0.03 0.97 FALSE
93 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MADD 0.20 0.07 enet 9 0.08 2.4e-09 -6.56 8.6 1.3e-17 0.32 0.92 0.01 FALSE
94 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMC3 0.05 0.04 lasso 3 0.05 3.8e-06 5.27 8.3 9.8e-17 0.73 0.01 0.98 FALSE
95 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1QTNF4 0.13 0.16 lasso 1 0.16 3.1e-09 12.17 -12.2 4.7e-34 -0.88 0.15 0.85 FALSE
96 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMC3 0.07 0.07 enet 7 0.06 1.4e-04 11.08 11.1 7.4e-29 0.82 0.01 0.98 FALSE
97 The Cancer Genome Atlas Brain Lower Grade Glioma ACP2 0.09 0.04 enet 12 0.06 5.0e-07 -4.55 6.5 5.9e-11 0.56 0.60 0.38 FALSE
98 The Cancer Genome Atlas Brain Lower Grade Glioma MADD 0.08 0.01 lasso 5 0.05 3.1e-06 11.03 11.5 7.9e-31 0.62 0.01 0.95 FALSE
99 The Cancer Genome Atlas Brain Lower Grade Glioma MTCH2 0.11 0.11 lasso 2 0.10 6.4e-12 12.03 12.0 1.9e-33 0.87 0.09 0.91 FALSE
100 The Cancer Genome Atlas Brain Lower Grade Glioma MYBPC3 0.03 0.01 blup 43 0.02 3.2e-03 11.05 -8.6 6.8e-18 -0.72 0.00 0.90 FALSE
101 The Cancer Genome Atlas Brain Lower Grade Glioma PSMC3 0.10 0.05 blup 39 0.08 3.7e-09 11.09 9.7 4.9e-22 0.79 0.02 0.98 FALSE
102 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C1QTNF4 0.19 0.19 lasso 3 0.19 3.2e-09 12.03 -12.0 1.9e-33 -0.87 0.09 0.91 FALSE
103 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PSMC3 0.09 0.07 blup 39 0.06 8.7e-04 11.05 11.2 3.9e-29 0.85 0.01 0.98 FALSE
104 The Cancer Genome Atlas Lung Adenocarcinoma C1QTNF4 0.03 0.02 blup 15 0.02 1.3e-03 13.53 -13.9 7.7e-44 -0.97 0.00 0.97 TRUE
105 The Cancer Genome Atlas Lung Adenocarcinoma MYBPC3 0.04 0.02 enet 10 0.04 2.9e-05 11.03 -8.7 4.2e-18 -0.68 0.01 0.98 FALSE
106 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MADD 0.16 0.05 blup 64 0.08 2.2e-09 -1.27 6.0 2.0e-09 0.10 0.98 0.00 TRUE
107 The Cancer Genome Atlas Prostate Adenocarcinoma AGBL2 0.04 0.03 blup 49 0.03 7.8e-04 -9.98 7.5 8.9e-14 0.41 0.18 0.07 FALSE
108 The Cancer Genome Atlas Prostate Adenocarcinoma MADD 0.15 0.04 enet 10 0.06 4.5e-07 -6.56 8.6 1.2e-17 0.30 0.20 0.03 FALSE
109 The Cancer Genome Atlas Prostate Adenocarcinoma NUP160 0.03 0.02 enet 7 0.02 6.3e-03 11.38 12.4 1.7e-35 0.83 0.01 0.87 FALSE
110 The Cancer Genome Atlas Prostate Adenocarcinoma PSMC3 0.02 0.02 blup 39 0.02 5.7e-03 11.09 9.1 1.3e-19 0.78 0.01 0.72 FALSE
111 The Cancer Genome Atlas Stomach Adenocarcinoma C1QTNF4 0.06 0.04 lasso 4 0.03 4.3e-03 12.05 -12.7 1.1e-36 -0.92 0.00 0.92 FALSE
112 The Cancer Genome Atlas Testicular Germ Cell Tumors MADD 0.21 0.04 blup 64 0.07 1.3e-03 -4.77 7.3 3.2e-13 0.28 0.07 0.05 FALSE
113 The Cancer Genome Atlas Thyroid Carcinoma C1QTNF4 0.04 0.01 blup 15 0.03 7.9e-04 13.53 -12.5 6.9e-36 -0.89 0.00 0.95 FALSE
114 The Cancer Genome Atlas Thyroid Carcinoma MADD 0.07 0.00 enet 11 0.03 6.7e-04 -4.97 8.6 1.1e-17 0.36 0.05 0.13 FALSE