[Hub]/) : Traits : Arm predicted mass (left) :

chr22:38,787,166-41,004,384

Best TWAS P=4.16e-11 · Best GWAS P=1.3e-11 conditioned to 0.00669

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MGAT3 0.08 0.04 lasso 4 0.04 4.3e-04 -5.4 5.3 9.4e-08 0.04 0.02 0.98 FALSE
2 GTEx Artery Aorta APOBEC3G 0.40 0.40 lasso 3 0.39 6.3e-23 5.0 5.3 1.2e-07 0.04 0.13 0.87 FALSE
3 GTEx Cells Transformed fibroblasts APOBEC3G 0.24 0.20 enet 11 0.24 9.4e-18 4.9 5.2 2.0e-07 0.05 0.15 0.84 FALSE
4 GTEx Heart Atrial Appendage MGAT3 0.14 0.14 lasso 2 0.12 3.5e-06 -5.6 5.6 2.6e-08 0.02 0.01 0.99 TRUE
5 GTEx Lung COX5BP7 0.13 0.12 lasso 3 0.12 1.7e-09 5.1 -5.3 1.2e-07 -0.04 0.11 0.89 FALSE
6 GTEx Nerve Tibial SYNGR1 0.26 0.18 enet 27 0.21 3.6e-15 -4.9 -5.5 3.9e-08 -0.04 0.07 0.93 FALSE
7 GTEx Nerve Tibial COX5BP7 0.44 0.25 enet 33 0.25 1.7e-17 3.7 -5.2 2.4e-07 -0.08 0.82 0.16 FALSE
8 GTEx Pituitary APOBEC3G 0.34 0.04 enet 11 0.11 1.2e-03 5.1 5.7 9.3e-09 0.04 0.09 0.44 TRUE
9 GTEx Skin Sun Exposed Lower leg MGAT3 0.13 0.05 lasso 3 0.02 4.7e-03 -5.6 5.6 2.7e-08 0.01 0.01 0.98 FALSE
10 GTEx Skin Sun Exposed Lower leg APOBEC3G 0.10 0.09 lasso 3 0.06 7.5e-06 5.0 5.3 1.4e-07 0.05 0.13 0.86 FALSE
11 GTEx Vagina APOBEC3G 0.23 0.07 lasso 5 0.06 1.8e-02 5.0 5.5 3.7e-08 0.05 0.09 0.26 FALSE
12 NTR Blood SYNGR1 0.03 0.03 enet 6 0.03 1.0e-10 4.9 5.3 1.4e-07 0.01 0.20 0.79 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma TNRC6B 0.02 0.01 blup 92 0.01 2.7e-03 -5.5 -6.0 1.5e-09 0.82 0.02 0.78 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 1.6e-04 -6.7 -5.8 8.5e-09 0.86 0.00 0.94 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADSL 0.07 0.02 blup 33 0.05 5.2e-04 -3.1 -5.2 1.7e-07 0.67 0.07 0.49 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 8.9e-03 -6.5 -6.0 2.2e-09 0.82 0.01 0.60 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 6.6e-03 -6.6 -6.5 7.0e-11 0.97 0.00 0.80 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 7.7e-02 -6.7 -6.6 4.2e-11 0.91 0.00 0.76 TRUE