[Hub]/) : Traits : Trunk fat percentage :

chr19:17,473,015-19,478,051

Best TWAS P=4.68e-22 · Best GWAS P=4.87e-22 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1683 0.09 0.06 enet 14 0.10 6.6e-12 -4.55 7.3 2.0e-13 0.78 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous KIAA1683 0.14 0.09 enet 6 0.16 2.5e-13 -2.76 6.5 9.1e-11 0.80 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous AC005253.4 0.11 0.06 enet 23 0.04 1.6e-04 0.17 5.9 4.4e-09 0.38 0.18 0.54 FALSE
4 GTEx Artery Tibial KIAA1683 0.16 0.08 enet 11 0.15 8.2e-12 -2.76 5.3 1.4e-07 0.60 0.49 0.51 FALSE
5 GTEx Colon Transverse SSBP4 0.18 0.01 enet 21 0.00 3.6e-01 6.05 -6.3 3.9e-10 -0.38 0.06 0.23 TRUE
6 GTEx Colon Transverse KIAA1683 0.15 0.02 lasso 3 0.02 3.3e-02 -4.65 7.9 3.0e-15 0.88 0.00 0.98 FALSE
7 GTEx Esophagus Muscularis KIAA1683 0.10 0.04 lasso 3 0.06 1.1e-04 -2.76 6.4 2.0e-10 0.80 0.01 0.99 FALSE
8 GTEx Muscle Skeletal PDE4C 0.11 0.05 lasso 6 0.06 7.7e-07 -3.21 -5.2 2.4e-07 -0.54 0.97 0.02 FALSE
9 GTEx Nerve Tibial KIAA1683 0.25 0.22 lasso 9 0.28 5.2e-20 9.65 7.6 3.3e-14 0.87 0.00 1.00 FALSE
10 GTEx Pancreas AC007192.6 0.19 0.00 enet 28 0.01 1.3e-01 9.18 -6.5 6.1e-11 -0.47 0.06 0.26 FALSE
11 GTEx Pituitary KIAA1683 0.43 0.25 lasso 3 0.17 3.9e-05 6.86 6.8 7.8e-12 0.80 0.02 0.92 FALSE
12 GTEx Testis PDE4C 0.39 0.44 lasso 2 0.43 5.8e-21 -5.40 -5.4 6.8e-08 -0.07 1.00 0.00 FALSE
13 GTEx Testis AC068499.10 0.38 0.41 lasso 3 0.40 6.8e-19 -5.40 -5.5 3.4e-08 -0.08 1.00 0.00 FALSE
14 GTEx Thyroid KIAA1683 0.11 0.07 enet 14 0.12 2.1e-09 6.86 8.8 2.1e-18 0.75 0.03 0.97 FALSE
15 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 9.65 -9.7 4.7e-22 -1.00 0.01 0.72 TRUE
16 METSIM Adipose IL12RB1 0.05 0.05 lasso 3 0.04 2.8e-07 5.70 -5.4 5.1e-08 -0.29 0.98 0.02 FALSE
17 NTR Blood IFI30 0.03 0.02 lasso 6 0.02 8.8e-08 8.72 7.3 3.2e-13 0.47 0.82 0.16 FALSE
18 ROSMAP Brain Pre-frontal Cortex PDE4C 0.18 0.12 enet 17 0.19 3.3e-24 -3.42 -6.4 1.4e-10 -0.57 0.99 0.01 FALSE
19 ROSMAP Brain Pre-frontal Cortex KIAA1683 0.23 0.14 bslmm 409 0.24 1.4e-30 -2.76 6.9 5.9e-12 0.84 0.00 1.00 FALSE
20 ROSMAP Brain Pre-frontal Cortex JUND 0.17 0.17 lasso 5 0.20 2.7e-25 9.65 8.4 5.8e-17 0.92 0.00 1.00 FALSE
21 ROSMAP Brain Pre-frontal Cortex KLHL26 0.22 0.13 bslmm 382 0.18 2.6e-22 -5.09 5.9 3.9e-09 0.05 1.00 0.00 TRUE
22 YFS Blood IFI30 0.08 0.04 bslmm 405 0.08 1.1e-23 -1.72 6.2 6.8e-10 0.42 1.00 0.00 FALSE
23 YFS Blood KIAA1683 0.51 0.40 enet 65 0.46 9.9e-171 9.64 7.5 6.4e-14 0.91 0.00 1.00 FALSE
24 YFS Blood MAST3 0.06 0.04 lasso 5 0.04 4.2e-12 9.18 -8.6 5.4e-18 -0.39 0.18 0.82 FALSE
25 The Cancer Genome Atlas Bladder Urothelial Carcinoma IL12RB1 0.07 0.02 lasso 3 0.01 6.4e-02 5.70 -5.8 7.7e-09 -0.32 0.13 0.16 FALSE
26 The Cancer Genome Atlas Bladder Urothelial Carcinoma KIAA1683 0.05 0.04 enet 6 0.05 4.9e-05 -2.76 5.5 4.2e-08 0.73 0.05 0.88 FALSE
27 The Cancer Genome Atlas Colon Adenocarcinoma IL12RB1 0.11 0.03 blup 58 0.03 7.3e-03 5.05 -5.1 2.7e-07 -0.19 0.19 0.10 FALSE
28 The Cancer Genome Atlas Glioblastoma Multiforme JUND 0.17 0.00 blup 57 0.03 5.4e-02 9.65 8.7 4.2e-18 0.71 0.00 0.70 FALSE
29 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1683 0.05 0.03 lasso 4 0.04 9.1e-06 -4.55 5.6 1.8e-08 0.68 0.16 0.84 FALSE
30 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IL12RB1 0.10 0.08 blup 58 0.09 6.9e-10 6.05 -5.3 1.2e-07 -0.30 1.00 0.00 FALSE
31 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 9.65 9.7 4.9e-22 1.00 0.00 0.99 FALSE
32 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma KIAA1683 0.09 0.07 lasso 8 0.12 2.1e-13 -2.77 6.2 6.5e-10 0.75 0.24 0.76 FALSE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAST3 0.04 0.02 blup 65 0.01 7.3e-02 9.18 -6.9 5.4e-12 -0.32 0.00 0.75 FALSE
34 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JUND 0.11 0.03 blup 58 0.04 1.4e-03 -3.73 8.3 1.3e-16 0.57 0.03 0.43 TRUE
35 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma KIAA1683 0.13 0.02 blup 65 0.05 1.0e-03 6.79 5.6 1.9e-08 0.79 0.00 0.98 FALSE
36 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 9.65 9.6 1.1e-21 1.00 0.00 0.99 FALSE
37 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1683 0.16 0.11 lasso 6 0.11 2.9e-12 -2.76 5.4 6.2e-08 0.70 0.88 0.12 FALSE
38 The Cancer Genome Atlas Brain Lower Grade Glioma MAST3 0.02 0.02 lasso 3 0.01 1.5e-02 8.97 -8.9 3.6e-19 -0.23 0.02 0.88 TRUE
39 The Cancer Genome Atlas Lung Adenocarcinoma IL12RB1 0.10 0.08 enet 13 0.07 3.9e-08 6.05 -5.3 1.1e-07 -0.29 1.00 0.00 FALSE
40 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IL12RB1 0.07 0.04 blup 58 0.06 4.9e-07 5.05 -6.8 1.3e-11 -0.26 0.86 0.12 FALSE
41 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA1683 0.09 0.05 lasso 4 0.06 1.3e-07 9.65 7.3 2.8e-13 0.86 0.00 1.00 FALSE
42 The Cancer Genome Atlas Soft Tissue Sarcoma KIAA1683 0.07 0.00 blup 64 0.01 4.5e-02 -4.65 5.8 6.9e-09 0.60 0.01 0.68 FALSE
43 The Cancer Genome Atlas Testicular Germ Cell Tumors CRTC1 0.33 0.08 lasso 5 0.12 3.6e-05 -5.09 -5.7 1.1e-08 0.02 0.04 0.52 FALSE
44 The Cancer Genome Atlas Testicular Germ Cell Tumors IL12RB1 0.10 0.01 enet 10 0.06 2.6e-03 1.76 -6.8 9.0e-12 -0.21 0.01 0.68 FALSE
45 The Cancer Genome Atlas Testicular Germ Cell Tumors KIAA1683 0.17 0.06 blup 65 0.06 3.0e-03 -4.09 5.9 3.6e-09 0.69 0.01 0.93 FALSE
46 The Cancer Genome Atlas Thyroid Carcinoma IL12RB1 0.08 0.04 lasso 3 0.05 8.9e-06 4.10 -5.8 5.8e-09 -0.25 0.31 0.51 FALSE
47 The Cancer Genome Atlas Thyroid Carcinoma KIAA1683 0.15 0.09 lasso 6 0.16 5.4e-15 6.79 6.2 6.9e-10 0.75 0.64 0.36 FALSE
48 The Cancer Genome Atlas Thyroid Carcinoma MAST3 0.04 0.02 lasso 2 0.00 3.4e-01 8.97 -8.9 6.5e-19 -0.24 0.02 0.78 FALSE