TWAS hub - SSBP4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.0871	0.0344	2.0e-03	0.042	NA	-0.001	NA	0.000	3.1e-04	NA	4.3e-01	NA	3.0e-01
2	GTEx	Cells Transformed fibroblasts	0.0950	0.0320	5.2e-04	0.067	NA	0.047	NA	0.055	9.0e-06	NA	2.0e-04	NA	5.5e-05
3	GTEx	Colon Transverse	0.1820	0.0650	3.4e-03	0.010	NA	-0.001	NA	-0.004	1.0e-01	NA	3.6e-01	NA	5.6e-01
4	GTEx	Esophagus Mucosa	0.1410	0.0390	4.4e-06	0.103	NA	0.121	NA	0.140	2.3e-07	NA	1.9e-08	NA	1.3e-09
5	GTEx	Esophagus Muscularis	0.0920	0.0310	3.3e-04	0.086	NA	0.039	NA	0.069	6.9e-06	NA	2.1e-03	NA	5.3e-05
6	GTEx	Liver	0.2640	0.0890	1.8e-03	0.037	NA	0.021	NA	0.059	3.3e-02	NA	8.4e-02	NA	1.0e-02
7	GTEx	Muscle Skeletal	0.0934	0.0291	4.8e-05	0.074	NA	0.068	NA	0.072	9.9e-08	NA	3.1e-07	NA	1.3e-07
8	GTEx	Pancreas	0.1530	0.0660	8.3e-03	-0.007	NA	-0.007	NA	0.025	9.7e-01	NA	8.7e-01	NA	3.1e-02
9	GTEx	Skin Sun Exposed Lower leg	0.1230	0.0320	6.4e-07	0.119	NA	0.084	NA	0.108	5.0e-10	NA	1.9e-07	NA	2.9e-09
10	GTEx	Thyroid	0.0880	0.0280	1.1e-04	0.113	NA	0.068	NA	0.096	5.4e-09	NA	7.0e-06	NA	8.2e-08
11	TCGA	Colon Adenocarcinoma	0.0810	0.0520	3.4e-04	0.045	0.045	0.071	NA	0.038	1.3e-03	1.3e-03	6.7e-05	NA	3.0e-03
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0379	0.0215	4.2e-05	0.028	0.042	0.032	NA	0.032	3.6e-04	1.6e-05	1.4e-04	NA	1.4e-04
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0245	0.0163	1.3e-03	0.017	0.028	0.017	NA	0.016	4.2e-03	3.7e-04	4.2e-03	NA	5.2e-03
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0590	0.0310	6.2e-05	0.068	0.063	0.073	NA	0.072	1.0e-04	1.8e-04	5.6e-05	NA	6.2e-05
15	TCGA	Brain Lower Grade Glioma	0.0306	0.0205	2.3e-03	0.029	0.024	0.032	NA	0.033	2.9e-04	7.9e-04	1.4e-04	NA	9.7e-05
16	TCGA	Lung Squamous Cell Carcinoma	0.0217	0.0133	2.5e-03	0.028	0.025	0.024	NA	0.026	3.0e-04	7.5e-04	8.3e-04	NA	5.3e-04
17	TCGA	Ovarian Serous Cystadenocarcinoma	0.0630	0.0360	1.3e-03	0.021	0.046	0.029	NA	0.025	1.4e-02	4.3e-04	4.7e-03	NA	7.3e-03
18	TCGA	Prostate Adenocarcinoma	0.0427	0.0188	6.3e-08	0.077	0.073	0.081	NA	0.077	1.8e-08	4.4e-08	8.4e-09	NA	2.0e-08
19	TCGA	Stomach Adenocarcinoma	0.0550	0.0360	6.9e-03	0.001	0.022	0.017	NA	0.006	2.7e-01	8.7e-03	1.9e-02	NA	1.2e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Breast Cancer	37.9	91.3	121.0	-10.9	-11.0	-3.2	-10.6	-7.8	-9.6	-10.5	-6.5	-11.0	-10.7	-9.0	-10.7	-10.3	-10.7	-7.6	-8.9	-9.9	-10.8	-8.0
Frequency of tiredness / lethargy in last 2 weeks	9.3	15.1	24.4	4.5	4.5	1.3	4.0	2.7	2.9	4.8	2.6	4.6	4.3	4.2	4.7	3.8	3.9	4.1	2.5	4.9	4.4	2.6
Family relationship satisfaction	7.8	9.6	12.9	3.2	3.2	3.4	3.4	3.1	3.6	2.7	3.1	3.2	3.3	2.7	3.2	3.3	3.5	1.5	3.6	1.9	3.3	2.8
Supplements: Glucosamine	5.8	7.5	11.1	2.9	2.9	0.2	3.0	3.3	2.9	2.6	3.3	2.8	3.0	2.5	2.7	3.0	2.9	2.2	2.8	3.0	2.7	1.6
Ever had prostate specific antigen (PSA) test	5.8	6.6	9.5	2.6	2.6	1.3	2.9	2.6	3.0	2.1	2.9	2.6	2.7	2.2	2.6	2.9	2.9	1.9	3.1	2.2	2.6	2.6
Hayfever/allergic rhinitis (self-reported)	5.6	7.5	16.2	3.1	3.1	1.8	2.8	1.4	2.2	3.2	1.4	3.1	3.0	4.0	3.0	3.0	2.8	3.0	1.9	3.1	3.0	0.7
Number of operations (self-reported)	5.6	8.3	13.7	-3.3	-3.4	-0.4	-3.0	-2.3	-2.6	-3.4	-1.7	-3.4	-3.2	-2.8	-3.2	-3.4	-3.2	-2.8	-2.2	-3.7	-3.4	-0.8
Nervous feelings	5.5	10.3	14.5	3.6	3.4	2.2	3.4	3.1	3.3	3.3	2.5	3.5	3.4	2.7	3.8	3.1	3.4	2.8	2.8	3.7	3.6	3.0
Allergy or Eczema	5.4	14.2	23.1	4.3	4.2	-0.9	3.8	3.3	3.0	4.4	3.0	4.2	4.1	4.4	3.9	4.8	3.9	4.1	2.6	4.5	4.2	0.6
Number of live births	5.3	7.6	14.5	3.1	3.0	0.0	2.8	2.5	2.2	3.1	1.4	3.1	2.9	3.0	3.3	3.1	2.8	3.8	2.0	3.0	3.0	1.6
Hayfever, allergic rhinitis or eczema	5.1	11.0	16.1	3.8	3.7	-0.3	3.5	3.1	2.8	3.7	2.6	3.8	3.6	4.0	3.5	4.0	3.4	3.8	2.5	3.8	3.6	1.0
Pulse wave peak to peak time	5.0	5.9	13.2	2.7	2.8	0.9	2.7	2.0	2.1	3.0	1.5	2.8	2.7	2.5	2.4	2.7	2.4	2.3	1.5	3.6	2.6	0.4
Heel T-Score	4.8	38.4	62.3	-7.3	-7.3	2.4	-6.7	-3.6	-5.1	-7.5	-3.3	-7.4	-7.1	-6.1	-7.9	-5.6	-6.7	-6.5	-4.8	-5.7	-7.3	-6.1
Crohns Disease (2017)	4.6	10.1	22.3	-4.1	-4.1	-0.3	-3.3	-0.7	-2.6	-4.3	-1.2	-4.1	-3.6	-3.0	-3.0	-3.4	-3.5	-2.4	-2.3	-4.7	-3.7	-0.8
Noisy workplace	4.4	5.5	8.1	-2.7	-2.8	-0.3	-2.5	-2.1	-1.7	-2.8	-1.9	-2.7	-2.7	-1.8	-2.6	-2.7	-2.5	-2.7	-1.8	-2.5	-2.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	4.1	5.3	7.4	2.5	2.4	2.4	2.5	1.9	2.3	2.4	1.4	2.5	2.4	2.3	2.7	2.2	2.3	2.1	1.9	2.5	2.3	2.4
Fed-up feelings	4.0	7.3	12.5	3.0	3.0	0.4	2.7	1.7	2.1	3.2	1.7	3.1	2.9	3.2	3.3	2.3	2.7	3.5	1.8	3.4	2.9	2.3
Number of children fathered	4.0	4.6	6.1	-2.1	-2.2	-2.0	-2.3	-2.2	-2.2	-1.8	-2.0	-2.1	-2.2	-1.7	-2.2	-2.2	-2.4	-1.7	-2.5	-2.0	-2.2	-2.4
Friendships satisfaction	4.0	5.0	8.9	2.1	2.1	3.0	2.1	2.1	2.7	1.6	2.0	1.9	2.2	1.9	2.4	2.5	2.4	1.6	2.6	1.8	2.2	2.5
Qualifications: None of the above	3.8	8.0	12.2	-3.5	-3.5	-1.9	-3.2	-1.9	-3.4	-3.4	-1.2	-3.4	-3.4	-2.0	-2.9	-3.0	-3.3	-1.6	-2.8	-2.8	-3.1	-2.1
Suffer from ‘nerves’	3.8	6.0	10.8	2.7	2.7	1.1	2.5	2.0	1.8	2.8	1.3	2.8	2.5	2.7	3.3	2.2	2.4	2.9	1.6	3.0	2.7	2.2
Frequency of depressed mood in last 2 weeks	3.7	5.2	6.7	2.5	2.5	1.2	2.4	2.1	2.0	2.5	2.5	2.5	2.6	2.3	2.4	2.1	2.5	1.7	2.1	2.5	2.4	2.1
Frequency of tenseness / restlessness in last 2 weeks	3.7	5.8	10.3	2.9	2.7	2.0	2.4	1.5	2.5	2.8	1.8	2.8	2.8	2.3	2.6	2.1	2.6	1.1	2.1	3.2	2.8	2.1
Overall health rating	3.6	7.7	16.2	2.8	2.9	0.7	3.2	2.3	2.5	2.5	2.8	2.9	2.9	3.0	3.3	2.4	3.0	1.9	2.9	2.4	2.9	4.0
Lupus	3.5	5.3	7.6	2.8	2.6	2.2	2.6	2.7	2.1	2.7	1.4	2.7	2.5	1.4	2.3	2.6	2.3	1.8	1.5	2.5	2.4	1.6
Serious illness, injury or assault of a close relative in last 2 years	3.4	4.0	8.1	2.6	2.6	-0.7	2.3	0.6	1.4	2.8	0.5	2.8	2.4	1.5	2.2	1.7	2.1	1.4	1.1	2.7	2.4	1.1
Worry (Nagel 2018)	3.3	7.0	10.7	3.1	3.0	0.0	3.0	2.2	2.3	3.0	1.7	3.2	2.9	2.1	3.2	2.6	2.8	2.5	2.0	3.3	3.1	2.3
Medication: Omeprazole	3.3	4.0	15.2	1.4	1.4	-0.6	2.0	3.0	2.1	0.8	3.9	1.4	1.6	1.8	1.8	2.2	2.0	0.2	2.5	1.2	1.8	2.7
Medication: Atorvastatin	3.3	4.1	6.2	-1.9	-1.9	-1.0	-2.4	-2.5	-2.4	-1.5	-1.5	-1.9	-2.0	-2.1	-2.3	-2.5	-2.2	-2.4	-2.4	-1.2	-1.9	-1.8
Crohns Disease (2012)	3.2	5.2	11.9	-3.1	-3.1	-0.4	-2.3	-0.1	-1.8	-3.5	-0.4	-3.1	-2.6	-2.3	-1.7	-2.6	-2.5	0.0	-1.3	-3.4	-2.6	0.8
Pulse wave reflection index	3.2	4.0	9.2	-2.2	-2.2	-1.2	-2.0	-1.7	-1.6	-2.3	-1.7	-2.1	-2.1	-2.5	-2.0	-1.9	-2.0	-2.0	-1.3	-3.0	-2.1	-0.4
Blood Red Count	3.1	29.9	61.3	-4.2	-4.4	-3.7	-5.2	-7.2	-6.8	-3.0	-7.3	-4.2	-5.0	-5.4	-6.0	-4.8	-5.7	-4.7	-6.7	-3.6	-5.2	-7.8
Height	3.1	60.5	102.0	9.7	9.8	5.6	8.7	3.9	6.5	10.1	2.6	9.7	9.4	6.8	8.0	8.6	8.8	4.1	6.2	8.8	9.5	4.4
Happiness	3.1	3.8	6.9	2.0	2.2	2.6	2.1	1.3	2.2	1.9	1.4	2.0	2.3	0.8	2.0	1.9	2.3	0.7	2.2	1.0	2.1	2.3
Depressed Affect (Nagel 2018)	3.0	6.4	11.2	2.7	2.8	-0.2	2.5	2.3	2.0	2.9	2.3	2.8	2.7	2.7	3.0	2.3	2.5	3.4	1.8	2.8	2.7	2.0
Waist Hip Ratio (WHR)	3.0	13.6	57.2	2.7	2.8	-7.6	3.6	2.8	4.5	1.5	4.4	2.7	3.2	3.0	2.8	3.4	3.9	-1.2	5.0	2.9	3.5	3.9
Stomach or abdominal pain in last month	3.0	3.7	5.9	1.6	1.7	0.3	2.2	2.3	2.2	1.2	2.3	1.8	1.8	1.7	2.3	2.3	2.1	1.5	2.3	1.4	2.1	2.4
Health satisfaction	3.0	4.0	6.0	2.1	2.1	1.2	2.3	1.7	2.3	1.8	2.3	2.1	2.1	1.7	2.2	1.9	2.2	1.5	2.2	1.3	2.0	2.4
Neuroticism	2.9	6.9	10.0	2.7	2.7	0.7	2.9	2.7	2.4	2.5	2.4	2.8	2.7	2.8	3.2	2.5	2.7	3.1	2.3	2.7	2.8	2.6
Neuroticism (Nagel 2018)	2.8	6.5	9.2	2.9	2.8	-0.1	2.6	2.2	2.2	2.9	2.2	2.9	2.8	2.3	3.0	2.4	2.7	2.5	2.0	3.0	2.9	2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	2.8	3.8	8.7	1.7	1.6	0.9	1.8	2.4	1.7	1.4	2.2	1.6	1.7	2.0	2.5	1.6	1.8	3.0	1.8	1.6	1.9	2.5
Standing height	2.8	27.6	43.7	6.3	6.5	4.3	5.8	3.2	4.3	6.6	1.9	6.5	6.2	4.8	5.5	5.5	5.9	3.3	4.1	5.9	6.4	3.2
Exposure to tobacco smoke outside home	2.8	3.8	7.7	2.1	2.1	0.9	1.8	1.8	1.6	2.2	1.5	2.0	2.1	2.2	2.3	1.7	1.9	2.8	1.4	2.3	2.0	1.2
LDL Cholesterol	2.7	4.3	6.8	-1.9	-1.8	-2.1	-2.3	-2.1	-2.2	-1.6	-1.6	-2.0	-2.0	-2.0	-2.4	-2.5	-2.1	-2.6	-2.2	-1.8	-2.1	-1.9
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	5.5	2.2	2.1	0.7	1.9	1.1	2.2	2.1	1.1	2.1	2.0	1.2	1.9	1.6	2.0	1.2	1.5	2.3	2.0	1.6
Smoking status: Previous	2.7	4.0	5.7	-2.2	-2.2	-0.5	-2.2	-1.5	-2.2	-2.2	-1.6	-2.4	-2.1	-1.9	-2.4	-1.9	-2.1	-2.1	-1.7	-2.0	-2.3	-1.5
Alzheimer’s Disease (including proxy)	2.6	3.8	8.2	-2.5	-2.0	-0.4	-1.8	-0.7	-1.2	-2.5	-0.2	-2.5	-2.2	-2.8	-1.8	-2.1	-1.8	-2.9	-0.7	-2.6	-2.1	0.7
Average weekly spirits intake	2.6	3.3	10.4	-2.2	-2.1	-2.9	-1.3	-0.4	-1.0	-2.6	0.0	-2.0	-2.0	-1.5	-1.2	-2.1	-1.7	-1.2	-0.7	-3.2	-2.0	0.6
Pulse wave Arterial Stiffness index	2.6	3.0	8.1	-1.9	-2.0	-0.6	-1.9	-1.5	-1.4	-2.1	-1.1	-2.0	-1.9	-1.8	-1.6	-1.9	-1.6	-1.9	-0.9	-2.8	-1.8	0.1
Long-standing illness, disability or infirmity	2.6	3.9	8.1	1.9	1.8	0.2	1.9	2.3	1.8	1.6	2.9	1.8	1.9	2.1	2.4	1.9	2.0	1.5	2.0	1.9	2.0	2.6
Bipolar Disorder or Schizophrenia	2.5	6.0	9.3	2.9	3.0	0.6	2.6	1.8	1.9	3.0	1.6	2.8	2.8	2.1	3.1	2.6	2.9	0.0	2.3	2.6	2.9	2.4
Relative age of first facial hair	2.5	5.1	8.2	-2.8	-2.8	-0.3	-2.3	-1.4	-2.2	-2.9	-1.9	-2.7	-2.8	-2.3	-2.1	-2.3	-2.6	-1.3	-2.0	-2.5	-2.7	-1.4
Serious illness, injury or assault to yourself	2.5	3.0	6.8	2.1	2.3	1.3	1.7	0.6	0.7	2.6	0.7	2.2	2.1	2.0	1.8	1.7	1.8	1.3	0.7	2.5	2.1	0.4
Sitting height	2.5	17.9	33.6	5.3	5.6	2.0	4.7	2.1	3.6	5.8	0.5	5.4	5.1	4.1	4.4	4.2	4.8	3.1	3.0	4.7	5.0	2.3
Past tobacco smoking	2.5	4.6	7.0	2.3	2.4	-0.1	2.5	1.6	2.6	2.2	1.8	2.5	2.4	1.6	2.5	2.1	2.4	1.7	2.2	2.0	2.5	1.9
Medication: Omeprazole (e.g. Zanprol)	2.5	3.1	9.9	1.3	1.2	-0.7	1.7	2.4	2.0	0.7	3.1	1.3	1.4	1.3	1.7	1.8	1.8	-0.2	2.3	0.9	1.5	2.9
Multivitamins +/- minerals	2.4	3.1	7.7	2.3	2.4	1.5	1.8	0.3	0.7	2.8	0.2	2.4	2.1	1.6	2.0	1.3	1.7	1.6	0.5	2.4	1.9	0.9
Neuroticism score	2.4	4.9	9.2	2.3	2.3	1.0	2.3	1.9	1.6	2.4	1.6	2.5	2.2	2.8	2.7	1.9	2.1	3.0	1.3	2.8	2.4	1.6
Mean time to correctly identify matches	2.4	4.6	10.5	1.9	1.8	3.2	1.9	2.0	1.7	1.7	2.7	1.8	2.0	2.8	2.4	1.7	1.9	2.3	1.8	2.4	1.9	2.0
Medication: Aspirin	2.4	3.2	5.3	-2.0	-2.1	-0.4	-1.9	-1.3	-1.7	-2.1	-0.8	-2.0	-2.1	-1.8	-2.3	-1.9	-1.9	-2.0	-1.5	-2.0	-2.0	-1.1
Breast cancer (self-reported)	2.4	2.8	4.7	2.0	2.0	-0.9	2.0	1.3	1.0	2.1	1.1	2.2	1.9	1.5	2.1	1.5	1.7	2.1	1.0	1.2	1.9	1.6
Miserableness	2.4	4.1	7.5	2.4	2.4	0.3	2.2	1.3	1.2	2.7	1.1	2.5	2.3	1.8	2.3	1.8	2.0	2.6	1.1	2.7	2.3	1.5
Depression (Nagel 2018)	2.3	3.5	4.8	1.9	2.0	-0.5	1.8	1.9	1.7	1.9	2.0	2.0	2.1	1.6	2.2	1.5	2.0	2.0	1.8	1.9	2.0	2.0
Ever had hysterectomy (womb removed)	2.3	2.6	3.9	-1.7	-1.7	-1.5	-1.6	-1.7	-1.6	-1.8	-1.4	-1.7	-1.7	-1.1	-1.9	-1.7	-1.6	-1.6	-1.2	-2.0	-1.8	-1.3
Hearing difficulty/problems with background noise	2.3	3.7	7.9	1.5	1.5	1.1	2.1	2.7	2.4	0.9	2.5	1.5	1.8	1.7	1.9	2.0	2.1	0.7	2.6	1.4	1.8	2.8
Forced expiratory volume in 1-second (FEV1), predicted	2.3	4.9	8.7	2.7	2.9	1.5	2.6	1.3	1.7	2.9	0.8	2.8	2.7	1.6	2.5	2.1	2.5	1.4	1.5	2.2	2.7	1.7
Schizophrenia (2014)	2.2	4.8	7.1	2.5	2.4	0.2	2.5	1.7	2.2	2.2	1.9	2.4	2.4	1.6	2.5	2.3	2.7	0.0	2.6	2.1	2.5	2.7
Lung FEV1/FVC ratio	2.1	10.5	19.3	4.1	4.0	-2.5	3.3	1.5	2.5	4.4	1.4	4.0	3.7	3.6	3.1	3.8	3.2	2.7	2.0	4.4	3.5	0.5
Illnesses of siblings: Diabetes	2.1	2.6	4.7	1.4	1.5	1.2	1.9	1.9	1.7	1.1	2.2	1.5	1.6	1.4	1.5	2.0	1.8	1.3	1.9	0.8	1.7	1.7
Blood White Count	2.0	15.1	40.6	-4.3	-4.4	-1.1	-3.3	-2.6	-2.4	-5.1	-0.7	-4.4	-4.0	-4.9	-3.9	-4.2	-3.3	-6.4	-1.2	-6.1	-3.8	1.0
Qualifications: CSEs or equivalent	2.0	2.6	5.1	-1.6	-1.5	-0.2	-1.4	-1.8	-1.7	-1.4	-2.0	-1.5	-1.5	-1.8	-1.6	-1.9	-1.6	-1.9	-1.5	-2.2	-1.8	-0.2
Qualifications: College or University degree	2.0	6.4	28.1	2.7	2.8	5.3	2.4	1.5	2.4	2.8	0.4	2.7	2.7	1.6	2.4	2.1	2.5	1.8	2.0	2.7	2.5	1.3
Cholesterol lowering medication	2.0	3.0	4.6	-2.0	-1.9	-1.2	-1.6	-1.3	-1.6	-1.9	-0.4	-1.9	-1.9	-1.5	-2.1	-1.5	-1.8	-1.8	-1.5	-2.1	-1.9	-1.8
Schizophrenia (2018)	1.9	3.9	6.2	2.4	2.5	-0.1	2.0	1.2	1.6	2.5	0.8	2.3	2.3	1.8	2.3	2.1	2.3	0.0	1.9	2.4	2.3	1.6
Angina (self-reported)	1.9	2.5	4.2	-1.5	-1.5	-0.8	-1.8	-1.9	-1.6	-1.3	-1.6	-1.6	-1.5	-2.0	-1.9	-2.1	-1.7	-0.9	-1.6	-1.4	-1.8	-0.9
Qualifications: nursing, teaching	1.9	3.0	5.7	1.5	1.5	1.7	1.8	1.9	2.2	0.9	2.2	1.4	1.6	1.5	1.4	1.7	1.9	1.3	2.4	1.7	1.6	1.9
Commuting to job workplace: Walk	1.9	2.0	5.5	2.0	1.9	1.2	1.4	-0.6	1.0	2.3	-0.9	1.9	1.7	1.0	0.6	1.2	1.3	-0.8	0.4	2.4	1.4	-0.7
Osteoporosis (self-reported)	1.9	2.3	4.1	1.9	1.9	0.2	1.9	0.7	1.3	2.0	0.1	2.0	1.8	1.5	1.9	1.4	1.6	1.0	1.0	1.2	1.6	1.6
Chronotype (morning person)	1.8	4.1	9.2	2.4	2.3	2.1	2.2	0.3	2.2	2.4	-0.0	2.4	2.2	1.9	2.4	1.4	1.9	1.0	1.2	3.0	2.1	2.3
Maternal smoking around birth	1.8	2.6	4.6	-1.9	-2.0	0.0	-1.5	-1.7	-1.2	-2.1	-1.5	-1.9	-1.8	-1.5	-1.6	-1.6	-1.5	-1.9	-0.8	-2.1	-1.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.2	8.5	-2.1	-2.1	0.2	-1.9	-2.5	-1.6	-1.9	-2.9	-1.9	-2.2	-2.1	-2.6	-2.0	-2.2	-1.5	-2.0	-1.4	-2.4	-2.2
Comparative height size at age 10	1.8	10.1	15.5	3.7	3.8	-0.3	3.8	2.3	2.9	3.6	2.1	3.7	3.8	2.7	3.2	3.7	3.8	1.2	3.2	3.3	3.9	2.6
Mean Putamen Volume	1.7	1.9	3.9	1.1	1.3	-0.9	1.3	1.4	1.9	0.9	1.3	1.1	1.4	1.1	1.1	1.4	1.6	0.7	2.0	1.8	1.4	1.6
Smoking Status	1.7	4.2	7.8	-2.4	-2.5	-0.2	-2.2	-1.0	-2.8	-2.3	-1.0	-2.4	-2.5	-1.2	-1.7	-2.4	-2.5	-0.0	-2.3	-2.6	-2.5	-0.8
Lung FVC	1.7	8.7	29.2	-2.2	-2.3	0.8	-3.2	-3.6	-3.5	-1.4	-3.7	-2.3	-2.7	-1.5	-3.2	-3.1	-3.2	-1.5	-4.0	-0.9	-2.9	-5.4
Impedance of leg (left)	1.7	8.5	14.1	3.5	3.4	-1.5	3.2	1.5	2.7	3.4	0.9	3.4	3.5	3.1	2.9	3.4	3.5	1.2	3.0	3.8	3.7	0.5
Allergy	1.7	3.8	6.3	-2.1	-2.0	1.3	-2.0	-2.1	-1.7	-1.9	-2.1	-2.1	-2.0	-2.5	-2.1	-2.3	-2.0	-1.9	-1.5	-1.9	-2.1	-0.9
Arm fat percentage (right)	1.7	6.9	38.4	-2.6	-2.6	-6.2	-2.1	-1.4	-1.6	-3.0	-0.7	-2.6	-2.5	-3.2	-2.3	-2.0	-2.2	-2.0	-1.2	-3.1	-2.5	0.7
Irritable Bowel Disease (IBD)	1.6	3.8	13.9	-2.6	-2.5	-1.4	-1.1	1.2	-0.0	-3.5	0.9	-2.5	-2.0	-2.2	-1.4	-1.3	-1.4	-1.1	0.3	-3.7	-1.9	1.4
Reaction Time	1.6	3.1	8.7	1.6	1.4	2.8	1.6	1.2	1.2	1.5	2.0	1.5	1.5	3.0	2.1	0.9	1.4	2.1	1.2	1.8	1.5	1.6
Vitamin and mineral supplements	1.6	2.2	5.5	-2.0	-2.0	-1.8	-1.5	0.1	-0.6	-2.4	0.0	-2.1	-1.8	-1.0	-1.5	-1.0	-1.4	-0.4	-0.5	-2.2	-1.6	-0.6
Worrier / anxious feelings	1.6	3.0	6.3	2.1	2.0	0.3	1.9	0.9	1.2	2.2	0.2	2.2	1.8	1.6	2.1	1.4	1.7	2.1	0.9	2.5	1.9	1.2
Qualifications: A levels/AS levels or equivalent	1.6	3.6	16.8	2.1	2.0	4.1	1.9	1.5	2.0	1.9	0.8	2.0	2.0	1.2	1.6	1.6	1.9	0.9	1.7	1.7	1.8	1.1
Arm predicted mass (right)	1.6	8.4	11.8	3.2	3.3	1.7	3.2	2.7	2.3	3.3	2.3	3.3	3.1	3.0	3.4	3.0	2.9	3.1	2.0	2.6	3.0	3.0
Intelligence (Savage-Jansen 2018)	1.5	4.6	8.1	2.0	2.2	2.4	2.3	2.1	2.5	1.5	2.2	2.0	2.1	1.8	2.0	2.2	2.5	1.2	2.8	2.0	2.4	1.7
Type 2 Diabetes (T2D) (2018)	1.5	2.7	6.1	-1.9	-1.8	-0.6	-1.6	-1.1	-1.6	-2.0	0.2	-1.9	-1.8	-1.8	-2.2	-1.8	-1.6	-2.5	-1.0	-1.8	-1.7	-1.0
Financial difficulties in last 2 years	1.5	2.1	3.9	1.7	1.7	1.2	1.6	1.0	1.1	1.8	1.4	1.8	1.6	1.1	1.4	1.3	1.5	0.9	0.9	2.0	1.6	1.2
Arm fat-free mass (right)	1.5	7.5	10.6	3.1	3.2	1.6	3.0	2.4	2.1	3.2	2.2	3.2	2.9	2.9	3.2	2.7	2.7	2.8	1.7	2.6	2.9	2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	3.4	-1.6	-1.6	-1.3	-1.8	-0.3	-1.6	-1.4	-0.8	-1.7	-1.6	-1.0	-1.1	-1.2	-1.6	0.8	-1.4	-1.0	-1.6	-1.2
Age at last live birth	1.5	2.2	3.2	1.8	1.7	1.7	1.8	0.7	1.7	1.6	-0.2	1.8	1.7	1.1	1.4	1.6	1.7	0.8	1.5	1.6	1.7	1.0
Arm fat percentage (left)	1.5	5.9	38.2	-2.3	-2.4	-6.2	-1.9	-1.2	-1.3	-2.7	-0.5	-2.4	-2.2	-3.0	-2.1	-1.8	-2.0	-1.7	-1.0	-2.8	-2.3	0.8
Commuting to job workplace: Public transport	1.5	1.8	3.4	1.7	1.7	0.3	1.5	0.5	1.1	1.8	0.2	1.6	1.6	1.9	1.5	1.4	1.3	1.4	0.7	1.8	1.5	0.0
Medication: Paracetamol	1.5	2.3	3.9	1.6	1.6	-0.1	1.7	1.6	1.6	1.4	1.4	1.6	1.6	1.0	2.0	1.9	1.6	1.7	1.4	0.9	1.7	1.4
Bipolar Disorder (2018)	1.4	2.3	3.9	1.7	1.7	1.1	1.6	1.4	1.1	1.6	1.6	1.7	1.6	1.1	2.0	1.5	1.7	0.0	1.4	1.2	1.8	1.7
Angina	1.4	1.8	3.2	-1.2	-1.2	-0.9	-1.5	-1.7	-1.4	-0.9	-1.5	-1.2	-1.2	-1.7	-1.6	-1.8	-1.4	-0.4	-1.4	-1.0	-1.5	-0.8
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	5.6	1.9	1.9	1.8	1.2	0.3	0.6	2.4	-0.3	1.9	1.6	1.5	1.3	1.4	1.2	1.8	0.1	2.4	1.5	-0.6
Blood clot in the leg (DVT)	1.4	1.8	5.0	-1.5	-1.5	-2.2	-1.3	-0.4	-1.0	-1.7	-0.1	-1.6	-1.4	-1.3	-1.4	-1.3	-1.2	-0.8	-0.7	-1.7	-1.4	-0.6
Mood swings	1.4	2.6	5.3	1.9	1.9	0.6	1.6	0.9	0.8	2.3	1.1	2.0	1.7	1.4	1.9	1.0	1.4	2.2	0.5	2.3	1.6	1.6
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	4.8	-1.6	-1.6	-2.2	-1.3	-0.5	-1.2	-1.7	-0.2	-1.6	-1.5	-1.1	-1.4	-1.3	-1.3	-0.7	-0.9	-1.7	-1.5	-0.8
Systolic blood pressure, automated reading	1.3	3.7	7.2	2.0	2.0	-0.2	1.8	1.2	1.8	2.0	1.5	2.0	2.0	2.1	2.7	1.9	1.8	2.7	1.5	1.9	1.9	2.3
Medication: Paracetamol	1.3	2.2	3.6	1.5	1.6	-0.4	1.6	1.2	1.6	1.5	1.0	1.6	1.6	1.3	1.9	1.7	1.5	1.9	1.2	1.3	1.7	1.1
Migraine (self-reported)	1.3	1.6	4.0	-1.1	-1.1	-0.8	-1.2	-1.7	-1.9	-0.9	-1.5	-1.1	-1.3	-0.5	-1.2	-1.4	-1.3	-0.2	-1.7	-0.5	-1.1	-2.0
Chest pain or discomfort	1.3	1.9	4.8	1.3	1.3	0.2	1.6	1.4	1.1	1.1	1.0	1.4	1.3	1.3	1.8	1.3	1.3	1.7	1.2	0.8	1.3	2.2
Commuting to job workplace: Car/motor vehicle	1.3	1.5	3.6	-1.4	-1.4	-1.1	-1.4	-0.5	-0.9	-1.4	-0.1	-1.4	-1.4	-1.6	-1.4	-1.2	-1.3	-1.1	-0.9	-1.9	-1.4	-0.2
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	4.0	-1.6	-1.6	0.4	-1.4	-0.8	-0.1	-2.0	-0.9	-1.8	-1.3	-0.9	-1.4	-1.1	-1.0	-1.6	0.0	-1.7	-1.3	-0.5
Arm fat-free mass (left)	1.3	6.7	9.3	2.9	3.0	1.7	2.8	2.2	2.0	3.0	2.0	3.0	2.8	2.5	3.0	2.6	2.6	2.6	1.7	2.2	2.7	2.8
Heart disease (siblings)	1.3	1.5	2.9	-1.0	-1.1	-0.4	-1.2	-1.7	-1.4	-0.9	-1.6	-1.1	-1.3	-1.2	-1.3	-1.5	-1.2	-1.3	-1.2	-1.6	-1.3	-0.6
Primary Biliary Cirrhosis	1.2	1.6	6.5	1.1	1.1	2.5	1.4	1.2	1.9	0.7	1.0	1.1	1.2	0.9	1.0	1.4	1.3	0.5	1.5	0.7	1.1	1.4
Relative age voice broke	1.2	1.8	3.6	-1.7	-1.7	0.7	-1.4	-0.4	-1.0	-1.9	-0.7	-1.7	-1.7	-1.3	-1.2	-1.2	-1.6	-0.1	-1.0	-1.5	-1.7	-1.2
Had other major operations	1.2	1.5	6.5	-1.2	-1.3	-2.5	-0.9	-0.8	-0.5	-1.5	0.0	-1.2	-1.2	-0.9	-1.3	-1.1	-0.9	-2.1	-0.2	-1.4	-1.2	0.1
Pain all over the body in last month	1.2	1.2	2.4	1.5	1.4	-0.8	1.3	-0.1	0.7	1.5	0.3	1.4	1.4	1.1	1.1	0.9	1.3	-0.2	0.8	1.4	1.5	0.7
Eye problems/disorders: Cataract	1.2	1.3	2.7	1.1	1.2	-1.4	1.3	0.9	1.4	0.9	0.9	1.1	1.4	0.7	0.9	0.8	1.4	-0.7	1.6	0.8	1.1	1.6
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	12.6	0.1	-0.0	3.5	0.6	1.5	2.4	-0.9	2.0	-0.1	0.3	-0.2	-0.3	1.2	0.8	-1.9	2.2	0.7	0.3	0.2
Medication: Aspirin	1.2	1.5	3.6	-1.3	-1.3	-0.7	-1.1	-0.8	-1.1	-1.4	-0.2	-1.3	-1.3	-1.2	-1.8	-1.2	-1.2	-1.9	-0.9	-1.5	-1.4	-0.8
Diastolic blood pressure, automated reading	1.2	3.6	8.2	-2.4	-2.4	-2.7	-2.0	-0.5	-0.9	-2.9	0.0	-2.5	-2.3	-1.1	-1.7	-1.2	-1.9	-0.4	-0.8	-2.8	-2.3	-0.7
Hearing difficulty/problems: Yes	1.1	1.6	4.4	-1.5	-1.5	-2.1	-0.8	0.7	-0.5	-2.0	0.8	-1.5	-1.3	-0.8	-1.6	-0.5	-1.0	-1.7	-0.1	-1.8	-1.3	-0.5
Impedance of leg (right)	1.1	5.5	8.6	2.6	2.6	-2.6	2.5	1.4	2.0	2.5	0.7	2.6	2.7	2.5	2.0	2.9	2.8	0.9	2.5	2.8	2.9	-0.4
Number of full brothers	1.1	1.3	3.3	1.7	1.5	0.2	1.0	0.6	0.8	1.8	0.6	1.4	1.4	1.4	1.0	1.3	1.1	0.7	0.6	1.3	1.2	-0.2
Arm predicted mass (left)	1.1	5.7	8.0	2.7	2.7	1.9	2.6	2.1	1.7	2.8	1.9	2.8	2.5	2.4	2.8	2.4	2.3	2.4	1.4	2.0	2.5	2.5
Ulcerative Colitis (UC)	1.0	1.8	6.2	0.1	0.2	-2.2	1.3	1.9	2.0	-0.9	2.0	0.2	0.4	-0.4	0.8	1.1	1.1	0.4	2.1	-1.0	0.7	2.5
Systolic Blood Pressure	1.0	4.8	8.8	2.3	2.2	1.5	2.1	1.7	2.1	2.0	2.1	2.2	2.1	2.2	3.0	1.9	2.1	2.5	1.9	2.2	2.2	2.9
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	3.3	-1.0	-1.1	-1.8	-1.0	-1.3	-1.1	-0.9	-0.5	-1.0	-1.2	-0.2	-0.8	-1.2	-1.3	0.2	-1.2	-0.6	-1.2	-0.9
Trunk fat-free mass	1.0	5.8	9.4	2.7	2.8	3.1	2.5	2.0	1.6	2.9	1.6	2.8	2.5	2.4	2.8	2.3	2.3	2.7	1.2	2.0	2.5	2.2
Medication: Cholesterol lowering	1.0	1.5	3.5	-1.6	-1.5	-1.0	-1.1	-0.7	-0.9	-1.9	-0.2	-1.5	-1.4	-1.1	-1.5	-1.1	-1.2	-0.9	-0.4	-1.5	-1.6	-0.4
Trunk predicted mass	1.0	5.9	9.0	2.7	2.8	3.0	2.5	2.0	1.6	3.0	1.7	2.8	2.5	2.5	2.9	2.3	2.3	2.7	1.3	2.1	2.5	2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.9	1.5	1.4	1.7	1.3	0.4	0.8	1.5	0.5	1.5	1.3	0.9	1.3	0.6	1.1	0.3	0.8	1.5	1.2	1.7
Birth weight	1.0	2.1	6.5	2.2	2.1	-0.8	1.6	-0.3	0.6	2.5	-0.2	2.1	2.0	0.5	1.0	1.5	1.6	0.4	0.6	1.7	1.7	-0.3
Leg fat percentage (right)	1.0	3.8	51.7	-1.2	-1.3	-7.2	-0.7	0.4	-0.3	-1.7	0.9	-1.3	-1.0	-1.6	-1.0	-0.0	-0.8	-0.3	0.2	-1.9	-1.1	0.7
Emphysema/chronic bronchitis	1.0	1.1	3.0	0.9	1.0	-0.8	0.9	1.5	1.1	0.9	1.7	0.8	1.0	1.1	1.0	1.0	1.0	1.0	1.1	1.2	0.9	0.8
Medication: Allopurinol	1.0	1.3	5.2	-1.2	-1.3	-0.9	-0.5	0.5	0.5	-1.9	1.0	-1.2	-1.0	-0.7	-1.2	-0.5	-0.6	-2.3	0.7	-1.7	-1.0	0.8
Mineral and other dietary supplements	1.0	1.4	3.9	-1.6	-1.6	-0.5	-1.4	-0.4	-0.6	-1.9	-0.5	-1.7	-1.5	-0.8	-1.0	-0.9	-1.1	-0.6	-0.4	-2.0	-1.2	-0.1
Age started oral contraceptive pill	1.0	1.2	6.3	0.8	0.7	2.5	0.8	0.5	1.5	0.4	0.5	0.7	0.9	-0.2	0.8	0.4	1.0	-1.2	1.5	0.5	0.8	2.2
Verbal and Numeric Reasoning (VNR)	0.9	2.2	3.4	1.4	1.5	1.4	1.5	1.3	1.9	1.3	1.6	1.4	1.6	1.4	1.3	1.6	1.6	1.1	1.7	1.8	1.6	0.8
Severe depression (siblings)	0.9	1.0	8.5	-0.9	-0.9	2.9	-0.5	-0.4	-0.6	-1.0	-0.5	-0.9	-0.8	-0.5	-0.8	-0.8	-0.7	-0.8	-0.3	-1.4	-1.0	-0.2
Hair/balding pattern: Pattern 3	0.9	1.3	2.8	-1.1	-1.0	0.1	-1.3	-1.3	-1.7	-0.7	-1.3	-1.1	-1.1	-1.6	-0.9	-1.4	-1.3	-0.4	-1.4	-1.1	-1.2	-0.9
Exposure to tobacco smoke at home	0.9	1.0	3.2	0.7	0.7	1.7	0.9	1.2	0.5	0.7	1.3	0.7	0.7	0.6	1.2	0.6	0.8	1.8	0.8	0.8	0.8	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.3	1.0	0.9	0.6	0.9	1.2	1.0	0.8	1.1	1.0	1.0	1.2	1.3	0.7	1.0	0.9	1.0	1.1	1.0	1.8
Medication: Blood pressure	0.9	1.6	4.8	-1.7	-1.8	-0.9	-1.4	-0.5	-0.7	-2.2	0.5	-1.8	-1.6	-0.7	-1.2	-1.4	-1.3	-0.9	-0.3	-1.3	-1.5	0.6
Had major operations	0.9	1.1	2.3	-1.3	-1.4	0.0	-1.0	-1.0	-0.8	-1.5	-0.5	-1.3	-1.2	-0.6	-1.0	-1.2	-1.2	-0.5	-0.6	-1.4	-1.3	0.3
Ever had bowel cancer screening	0.9	1.0	2.8	1.2	1.3	-0.2	0.8	0.4	0.6	1.5	0.2	1.2	1.2	1.2	1.0	1.1	1.1	0.9	0.4	1.7	1.2	-0.3
Medication for cholesterol	0.9	1.4	4.4	1.6	1.6	1.0	1.0	-0.1	0.3	2.1	-1.0	1.7	1.3	0.8	1.2	0.6	0.9	1.3	-0.1	1.7	1.3	0.2
High cholesterol (Self-reported)	0.9	1.6	4.2	-1.6	-1.4	-2.1	-1.2	-0.5	-1.0	-1.7	0.0	-1.5	-1.3	-1.0	-1.5	-0.6	-1.2	-0.9	-0.6	-1.6	-1.5	-1.1
Alcohol drinker status: Never	0.9	1.0	2.4	1.4	1.4	0.3	1.0	-0.8	1.0	1.5	-0.4	1.4	1.2	0.4	1.0	0.4	1.1	-0.1	0.6	1.3	1.0	1.0
Risk taking	0.9	1.4	17.0	-0.5	-0.6	4.1	-0.6	-0.8	-0.8	-0.3	-1.2	-0.5	-0.6	-0.1	-0.0	-1.0	-0.8	0.6	-1.0	-0.8	-0.8	0.1
Alcohol drinker status: Previous	0.9	1.0	4.9	-0.7	-0.9	2.2	-0.5	-0.8	-0.1	-1.0	-0.4	-0.7	-0.8	-1.2	-0.8	-0.7	-0.7	-2.2	-0.4	-1.0	-0.8	0.4
Alzheimer’s Disease (in father)	0.8	0.8	2.3	1.2	1.2	-0.5	0.9	0.2	0.3	1.5	0.4	1.3	1.1	-0.2	1.0	0.4	0.8	-0.3	0.3	1.2	1.0	1.4
Diabetes (father)	0.8	1.0	4.3	0.5	0.4	-1.7	0.4	2.1	0.3	0.5	1.7	0.4	0.4	0.9	0.9	0.6	0.5	1.9	0.2	0.7	0.6	0.5
Age when periods started (menarche)	0.8	1.9	6.4	-0.9	-1.0	0.7	-1.2	-1.9	-1.8	-0.5	-2.5	-0.8	-1.1	-0.9	-1.2	-1.7	-1.3	-1.4	-1.9	-0.3	-1.0	-1.9
High blood pressure	0.8	2.3	6.9	-2.1	-2.1	-1.5	-1.6	0.2	-0.6	-2.6	1.2	-2.1	-1.9	-0.7	-1.3	-1.0	-1.4	0.0	-0.2	-2.2	-1.8	-0.4
Number of incorrect matches in round	0.8	1.3	2.6	1.3	1.3	1.6	1.1	1.0	0.7	1.4	1.1	1.3	1.2	0.4	1.4	0.9	1.2	0.7	0.8	0.8	1.2	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.7	4.5	-1.3	-1.4	-0.3	-1.1	-1.6	-0.8	-1.3	-2.1	-1.2	-1.4	-1.4	-1.8	-1.0	-1.5	-0.8	-1.2	-0.4	-1.5	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	6.3	2.0	2.0	1.4	1.2	0.4	0.6	2.5	-0.5	1.9	1.7	2.1	1.3	1.2	1.3	1.9	0.2	2.4	1.6	-1.3
Peak expiratory flow (PEF)	0.8	1.8	9.8	-0.4	-0.4	-1.4	-1.2	-1.8	-1.9	0.3	-2.3	-0.4	-0.7	-0.5	-1.2	-1.0	-1.1	0.4	-2.0	0.1	-0.7	-3.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.6	1.5	1.5	1.5	1.1	0.6	0.5	1.9	-0.3	1.5	1.3	0.7	1.2	1.1	1.0	0.8	0.1	1.1	1.4	-0.3
Glaucoma (self-reported)	0.8	1.0	3.3	-0.8	-0.8	-1.8	-1.0	-1.3	-1.5	-0.5	-0.7	-0.8	-0.9	-0.6	-0.9	-0.6	-1.0	-0.8	-1.2	-0.2	-0.7	-1.2
Forced vital capacity (FVC), Best measure	0.8	3.1	8.0	2.1	2.2	2.8	1.5	0.6	0.7	2.5	-0.4	2.1	1.8	2.1	1.7	1.3	1.6	1.8	0.5	2.3	1.9	-0.5
Body fat percentage	0.8	3.2	45.7	-0.8	-0.8	-6.8	-0.3	-0.2	-0.0	-1.3	0.3	-0.8	-0.7	-1.7	-0.7	-0.1	-0.4	-0.9	0.4	-1.4	-0.7	1.8
Worry too long after embarrassment	0.8	1.4	3.5	1.2	1.2	1.7	1.1	0.7	0.8	1.3	0.9	1.3	1.1	1.3	1.2	1.1	1.1	1.1	0.6	1.9	1.4	0.4
Hypertension (Self-reported)	0.8	2.3	7.2	-2.1	-2.1	-1.4	-1.5	0.1	-0.5	-2.7	1.2	-2.1	-1.8	-0.9	-1.3	-1.2	-1.3	-0.3	-0.1	-2.4	-1.8	-0.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	4.4	1.1	1.1	2.1	0.6	-0.5	0.1	1.5	-0.8	1.1	1.1	0.9	0.9	0.6	0.7	0.2	0.1	1.5	1.1	0.4
Vascular/heart problems diagnosed by doctor	0.8	2.1	6.7	2.0	2.0	0.9	1.5	0.0	0.5	2.6	-1.1	2.1	1.8	0.9	1.4	1.1	1.3	0.3	0.1	2.1	1.8	0.1
Body Mass Index (BMI) (2010)	0.7	1.0	3.0	-1.0	-1.0	-0.9	-0.9	-0.6	-1.2	-1.1	-0.2	-1.0	-1.1	-0.9	-1.3	-1.2	-1.0	-1.7	-0.7	-0.8	-1.0	-0.0
Triglycerides	0.7	1.1	2.3	-1.2	-1.1	0.3	-1.1	-0.4	-1.1	-1.1	0.4	-1.2	-1.2	-1.5	-1.2	-1.0	-1.1	-0.7	-1.1	-1.5	-1.1	-0.8
Blood Platelet Count	0.7	7.7	16.0	-3.8	-3.6	-0.9	-3.2	-1.4	-2.3	-4.0	-0.6	-3.8	-3.4	-1.5	-2.8	-3.1	-2.9	-2.3	-1.7	-3.2	-3.2	-1.2
Trunk fat percentage	0.7	2.7	39.2	-0.5	-0.5	-6.3	0.0	-0.3	0.2	-1.0	0.3	-0.5	-0.4	-1.6	-0.4	0.0	-0.1	-1.0	0.6	-1.1	-0.3	2.1
Body mass index (BMI)	0.7	3.2	17.7	-1.9	-1.9	-4.2	-1.4	-0.2	-0.9	-2.1	0.5	-1.8	-1.8	-2.0	-1.3	-1.2	-1.6	-0.5	-0.8	-2.5	-1.9	1.2
Waist circumference	0.7	2.6	30.1	-0.1	-0.0	-5.5	0.6	1.3	1.1	-0.7	1.9	-0.1	0.2	-0.5	0.5	0.8	0.6	-0.5	1.4	-0.6	0.2	2.8
Had menopause	0.7	0.9	2.0	0.9	1.0	-0.8	0.8	0.5	0.8	1.1	-0.0	1.0	1.1	1.3	1.1	1.1	0.9	1.4	0.7	1.4	1.0	-0.0
Medication: Ramipril	0.7	0.9	2.6	-0.8	-0.9	-0.7	-0.1	0.7	1.1	-1.6	1.2	-0.9	-0.6	-1.0	-0.4	-0.2	-0.2	-0.7	1.1	-1.6	-0.7	1.6
Fluid intelligence score	0.7	1.5	2.6	1.1	1.1	1.6	1.0	1.0	1.6	1.0	1.4	1.0	1.2	1.3	1.4	1.2	1.2	1.5	1.2	1.3	1.2	0.6
Falls in the last year	0.7	1.0	2.4	-0.8	-0.8	-1.1	-1.3	-1.2	-1.6	-0.5	-1.5	-0.9	-0.8	-0.5	-1.0	-0.8	-1.0	-0.4	-1.3	-0.3	-0.8	-1.3
Mouth/teeth dental problems: Dentures	0.7	1.1	2.7	-1.4	-1.5	0.0	-1.3	0.4	-0.8	-1.6	1.0	-1.5	-1.4	-0.8	-0.8	-0.9	-1.2	-0.2	-0.6	-1.3	-1.1	-0.4
Medication: Lansoprazole	0.7	0.8	3.3	-0.9	-1.0	-1.8	-1.1	-0.7	-1.1	-0.8	-0.3	-1.0	-1.0	-0.2	-0.4	-1.0	-1.1	-0.2	-1.0	-0.7	-0.9	-0.1
Illnesses of father: None of the above (group 1)	0.7	0.9	1.8	1.0	1.1	-0.7	1.1	0.0	1.0	1.0	-0.5	1.0	1.1	1.1	0.9	1.0	1.1	0.6	0.8	1.3	1.1	0.4
Number of self-reported non-cancer illnesses	0.7	1.2	2.4	-1.2	-1.2	-0.8	-1.1	-1.2	-0.7	-1.4	0.1	-1.3	-1.1	-0.4	-1.1	-1.2	-1.0	-1.4	-0.5	-1.5	-1.4	0.1
Mother’s age at death	0.7	0.8	3.0	-0.8	-0.7	-0.4	-0.8	-0.7	-1.4	-0.3	-1.4	-0.6	-0.8	-0.7	-0.6	-0.5	-1.1	0.3	-1.5	-0.3	-0.9	-1.7
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.2	1.2	1.3	0.7	1.3	0.5	0.4	1.4	0.1	1.5	1.2	0.5	1.0	0.6	0.9	0.6	0.4	1.3	1.0	0.5
Medication: Bendroflumethiazide	0.7	1.1	3.0	-1.4	-1.4	-0.9	-1.1	0.1	-1.0	-1.6	0.3	-1.4	-1.3	-0.7	-0.7	-0.8	-1.1	-0.1	-0.6	-1.7	-1.2	-0.5
Leg fat percentage (left)	0.7	2.7	40.4	-0.7	-0.7	-6.4	-0.2	0.7	0.1	-1.2	1.1	-0.7	-0.5	-1.2	-0.3	0.3	-0.3	0.1	0.5	-1.3	-0.6	1.3
Fractured/broken bones in last 5 years	0.7	0.9	1.6	1.0	1.1	0.6	1.0	0.6	0.9	1.0	1.3	1.0	1.1	-0.2	0.6	1.1	1.1	-0.4	1.1	0.7	1.1	0.8
Schizophrenia vs Biploar Disorder	0.6	0.8	2.6	0.9	0.8	0.0	1.2	1.1	1.6	0.4	1.6	0.8	0.9	0.0	0.0	0.0	1.1	0.0	1.5	0.0	0.9	0.0
HDL Cholesterol	0.6	1.0	4.3	-0.1	-0.2	-0.6	-0.8	-1.8	-1.2	0.5	-2.1	-0.1	-0.3	-0.9	-1.0	-0.7	-0.8	-0.5	-1.6	0.1	-0.5	-1.9
BMI	0.6	3.7	24.9	-1.8	-1.9	-5.0	-1.0	0.7	-0.4	-2.4	1.9	-1.8	-1.7	-2.0	-1.3	-0.8	-1.3	-0.6	-0.2	-2.9	-1.7	1.5
Cardiovascular Disease	0.6	1.9	5.7	-1.9	-1.9	-1.3	-1.3	-0.3	-0.6	-2.4	1.3	-1.9	-1.6	-0.8	-1.3	-0.9	-1.2	-0.5	-0.2	-2.1	-1.5	-0.4
Respiratory disease	0.6	1.4	2.4	-1.3	-1.4	-0.8	-1.5	-0.6	-1.4	-1.1	-0.4	-1.3	-1.4	-1.2	-0.8	-1.4	-1.5	-0.9	-1.5	-1.2	-1.3	-0.5
Hair Pigment	0.6	18.5	23.6	-4.3	-4.3	-4.8	-4.9	-3.5	-4.6	-3.8	-3.9	-4.5	-4.6	-3.7	-4.6	-4.3	-4.8	-2.5	-4.6	-3.9	-4.8	-4.7
Sensitivity / hurt feelings	0.6	1.0	3.8	0.5	0.5	-0.4	0.5	1.5	0.6	0.5	1.6	0.5	0.6	1.9	1.2	0.9	0.7	2.0	0.6	0.9	0.8	0.4
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	3.7	0.6	0.5	0.1	0.1	0.8	-0.1	0.7	0.5	0.5	0.3	1.2	0.8	0.7	0.2	1.9	-0.3	0.7	0.4	-1.2
Impedance of arm (right)	0.6	2.8	8.0	-1.3	-1.2	-2.2	-1.4	-2.6	-1.3	-1.2	-2.8	-1.3	-1.2	-2.0	-1.8	-1.4	-1.1	-2.6	-0.9	-0.7	-0.9	-1.8
Asthma	0.6	1.2	2.1	-1.2	-1.3	-0.8	-1.1	-0.8	-0.9	-1.3	-0.6	-1.2	-1.3	-0.9	-0.8	-1.4	-1.2	-1.4	-1.1	-1.3	-1.2	0.1
Breastfed as a baby	0.6	0.7	3.6	-0.6	-0.7	1.9	-0.9	0.2	-1.2	-0.3	-0.7	-0.7	-0.7	0.1	-0.5	-0.5	-0.9	0.7	-1.1	-0.4	-0.6	-1.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.7	-1.1	-1.0	0.2	-0.7	-1.1	-0.4	-1.1	-0.5	-0.9	-0.9	-0.8	-1.1	-0.9	-0.8	-1.3	-0.4	-0.6	-0.9	0.4
Gout (self-reported)	0.6	0.8	3.4	-0.4	-0.4	-1.8	0.3	1.1	1.2	-0.9	1.8	-0.3	-0.1	0.7	-0.3	0.2	0.3	-1.2	1.2	-0.7	-0.1	0.9
Medication: Ibuprofen	0.6	0.7	3.1	0.4	0.5	-1.7	0.3	1.4	0.0	0.4	1.0	0.3	0.4	-0.8	1.0	0.4	0.4	0.7	0.4	0.6	0.5	1.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	10.7	-0.3	-0.5	-3.3	-0.3	-0.1	0.1	-0.6	0.1	-0.4	-0.3	-0.4	-0.1	-0.2	-0.2	-0.3	0.1	-0.5	-0.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	4.3	0.2	0.3	-1.4	0.4	0.9	0.8	-0.1	1.6	0.2	0.4	0.7	0.6	0.3	0.6	0.0	1.1	0.6	0.3	2.1
Whole body fat-free mass	0.6	3.2	4.7	2.0	2.1	2.1	1.9	1.4	1.0	2.2	1.3	2.1	1.8	1.7	2.2	1.6	1.6	2.1	0.7	1.4	1.8	2.1
Average weekly red wine intake	0.6	0.9	3.9	-0.9	-0.9	-0.6	-0.5	0.5	0.5	-1.5	0.2	-1.0	-0.6	-1.4	-0.9	-0.7	-0.4	-2.0	0.8	-1.0	-0.9	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	0.8	0.7	1.3	0.6	0.5	1.0	0.7	1.0	0.7	0.9	1.1	0.6	0.8	0.8	0.2	0.9	1.3	0.8	0.3
Back pain experienced in last month	0.6	0.9	4.3	0.5	0.6	-0.0	0.8	1.2	0.4	0.6	1.5	0.7	0.6	1.4	1.4	0.7	0.5	2.1	0.4	0.5	0.6	0.6
Asthma (self-reported)	0.6	1.2	2.1	-1.2	-1.3	-0.7	-1.1	-0.6	-0.8	-1.4	-0.4	-1.2	-1.3	-0.9	-0.7	-1.4	-1.2	-1.3	-0.9	-1.4	-1.2	0.3
Whole body water mass	0.6	3.7	5.3	2.1	2.2	2.2	2.0	1.6	1.2	2.3	1.5	2.2	1.9	1.8	2.3	1.7	1.7	2.1	0.9	1.5	1.9	2.3
Ever smoked	0.6	1.0	2.8	-0.8	-0.8	1.3	-1.0	-0.9	-1.7	-0.6	-1.3	-0.9	-1.0	0.2	-0.8	-0.9	-1.1	-0.1	-1.4	-0.4	-1.0	-1.1
Neuroticism (2016)	0.5	0.7	2.2	0.7	0.7	1.2	0.6	-0.0	0.5	1.0	0.4	0.8	0.5	0.6	1.1	0.5	0.6	1.5	-0.2	1.3	0.9	1.0
Rheumatoid Arthritis	0.5	0.6	2.6	0.4	0.3	1.0	0.6	1.3	0.8	0.1	0.8	0.3	0.4	1.0	0.9	1.0	0.5	1.6	0.8	0.6	0.4	0.4
Medication for hormone replacement therapy	0.5	0.5	1.7	-0.9	-1.0	0.8	-0.6	-0.2	-0.3	-1.3	0.4	-1.0	-0.8	-0.7	-0.6	-0.4	-0.5	-1.2	0.2	-0.7	-0.6	0.3
Medication: Co-codamol	0.5	0.5	2.6	0.5	0.5	1.4	0.2	0.6	0.9	0.3	1.6	0.3	0.5	0.9	0.5	0.4	0.6	0.1	0.9	0.4	0.6	0.6
Alcohol usually taken with meals	0.5	0.8	4.0	0.4	0.4	0.0	0.9	0.9	1.6	-0.1	0.7	0.4	0.7	0.2	0.9	0.6	0.9	0.5	1.7	0.1	0.4	2.0
Medication: Simvastatin	0.5	0.7	2.3	-1.0	-1.0	-1.1	-0.4	0.3	-0.1	-1.4	0.8	-1.0	-0.8	-0.5	-0.9	-0.2	-0.6	-0.6	0.3	-1.5	-1.1	-0.1
Illnesses of siblings	0.5	0.7	2.2	-0.8	-0.7	-0.2	-0.9	-0.8	-0.8	-0.5	-1.5	-0.7	-0.7	-1.2	-0.7	-0.6	-0.8	-0.4	-0.9	-0.6	-0.6	-1.5
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	5.9	1.5	1.5	0.9	0.4	-0.5	-0.3	2.2	-1.4	1.4	1.1	1.3	0.6	0.6	0.6	1.6	-0.8	1.9	1.0	-2.4
Lung cancer (father)	0.5	0.6	2.8	0.7	0.7	0.4	0.9	-0.5	0.9	0.6	0.1	0.8	0.6	1.7	0.4	1.0	0.8	0.3	0.7	0.9	0.9	-0.6
Illnesses of mother	0.5	0.7	4.3	0.6	0.6	2.1	0.2	-0.7	-0.3	0.9	-1.3	0.7	0.4	-0.1	0.1	0.5	0.2	-0.1	-0.6	1.1	0.6	-1.2
Arm fat mass (right)	0.5	1.9	18.1	-1.0	-1.0	-4.2	-0.6	-0.3	-0.3	-1.3	0.3	-1.0	-0.9	-1.7	-0.7	-0.5	-0.8	-0.6	-0.2	-1.7	-1.0	1.6
Birth weight of first child	0.5	0.9	4.3	-0.1	-0.0	-1.8	0.5	1.2	1.1	-0.6	2.1	-0.1	0.3	-0.4	0.2	0.7	0.5	-0.2	1.4	-0.8	0.2	1.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.3	0.8	0.8	0.2	0.7	0.7	0.7	0.8	0.7	0.8	0.8	0.6	1.0	0.7	0.7	1.5	0.6	0.6	0.6	0.8
Eye problems/disorders: None of the above	0.5	0.6	5.9	0.4	0.4	2.4	0.1	-0.9	-0.1	0.7	-1.1	0.5	0.2	-0.1	-0.4	0.3	0.0	-0.3	-0.5	0.5	0.2	-1.3
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.3	-0.9	-0.8	0.2	-0.7	-1.1	-0.9	-0.7	-0.9	-0.7	-0.8	0.0	-0.5	-0.8	-0.8	0.1	-0.7	-0.8	-0.8	-0.5
Heart disease (mother)	0.5	0.6	2.6	0.7	0.7	-0.1	0.8	0.8	0.9	0.5	1.0	0.6	0.8	0.4	0.8	0.4	0.8	0.1	1.0	0.4	0.7	1.6
Leg fat mass (right)	0.5	1.9	30.3	-0.4	-0.4	-5.5	-0.0	0.5	0.0	-0.8	0.9	-0.4	-0.4	-0.9	-0.2	0.3	-0.2	0.2	0.3	-1.1	-0.4	1.4
Illnesses of father: Heart disease	0.5	0.6	3.3	0.7	0.7	1.8	0.8	0.4	0.6	0.6	0.7	0.8	0.7	0.1	0.7	0.3	0.6	0.0	0.8	0.1	0.5	1.6
Wears glasses or contact lenses	0.5	0.6	1.8	0.4	0.4	-0.8	0.7	1.1	0.8	0.1	1.3	0.4	0.5	0.6	0.7	1.0	0.6	1.1	1.0	0.5	0.5	0.5
Medication: Blood pressure	0.5	1.0	3.5	-1.2	-1.1	-1.2	-0.6	1.1	0.2	-1.7	1.6	-1.2	-0.9	-0.6	-0.7	-0.3	-0.4	-0.3	0.6	-1.9	-0.8	0.2
Myopia	0.5	0.7	8.4	0.5	0.5	2.9	0.4	-1.0	-0.2	0.7	-1.3	0.6	0.3	-0.3	-0.1	0.3	0.1	-0.5	-0.3	0.8	0.3	-0.3
Pain experienced in last month	0.5	0.9	2.1	-0.8	-0.7	-0.9	-0.8	-0.7	-0.5	-0.9	-0.7	-0.8	-0.8	-1.4	-1.4	-0.7	-0.7	-1.4	-0.3	-1.4	-0.9	-0.6
Basal cell carcinoma (self-reported)	0.5	0.6	1.7	-0.7	-0.8	1.3	-0.7	-1.2	-0.3	-0.8	-0.8	-0.8	-0.7	-0.7	-0.7	-0.8	-0.7	-1.3	-0.4	-0.7	-0.7	-0.1
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.1	-0.8	-0.8	0.7	-0.9	-0.7	-0.3	-0.8	-0.3	-0.9	-0.7	-1.4	-0.9	-0.9	-0.8	-0.5	-0.4	-1.1	-1.0	0.3
Alzheimer’s Disease (in mother)	0.4	0.4	1.4	-0.6	-0.6	1.2	-0.1	0.7	0.4	-1.1	0.6	-0.7	-0.4	-0.3	-0.0	-0.1	-0.0	-0.5	0.7	-0.9	-0.3	1.1
HbA1C	0.4	0.4	2.9	-0.3	-0.4	-0.0	0.2	1.3	0.5	-0.7	1.7	-0.2	-0.1	0.1	0.2	-0.3	0.1	-0.3	0.7	-0.6	-0.1	1.2
Ulcerative Colitis	0.4	0.5	1.7	-0.2	-0.2	-1.2	0.5	0.9	1.1	-1.0	0.7	-0.2	-0.2	-0.6	-0.1	0.4	0.4	0.0	1.2	-1.0	0.0	1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.6	-0.2	-0.2	-0.5	-0.8	-0.8	-1.0	0.2	-0.2	-0.2	-0.4	-0.3	-0.7	-0.7	-0.6	-0.4	-1.3	0.4	-0.4	-1.6
Current tobacco smoking	0.4	0.6	2.0	-0.7	-0.8	0.1	-0.7	-0.3	-1.4	-0.5	-0.2	-0.7	-0.9	0.8	-0.0	-0.7	-0.9	1.4	-1.2	-0.4	-0.7	-0.4
Medication: Atenolol	0.4	0.5	1.3	-0.8	-0.8	-0.6	-0.9	-0.6	-0.4	-0.9	-0.2	-0.9	-0.8	-0.4	-0.4	-1.1	-0.7	-0.1	-0.5	-0.9	-0.8	0.7
Trunk fat mass	0.4	1.9	26.3	0.1	0.1	-5.1	0.6	0.4	0.6	-0.3	0.8	0.1	0.2	-1.0	0.2	0.6	0.4	-0.2	0.9	-0.6	0.2	2.4
Hair/balding pattern: Pattern 2	0.4	0.6	1.5	0.6	0.6	-0.8	0.6	0.7	0.8	0.5	1.2	0.5	0.7	0.3	0.5	1.1	0.8	-0.8	1.0	0.4	0.7	0.9
Forced vital capacity (FVC)	0.4	1.7	6.1	1.5	1.6	2.5	0.7	-0.0	0.1	2.0	-1.1	1.5	1.2	1.2	0.9	0.6	0.9	1.5	-0.3	1.6	1.2	-1.4
Diabetes (self-reported)	0.4	0.7	1.4	-0.8	-0.8	-0.9	-0.8	0.2	-0.6	-0.9	1.1	-0.9	-0.8	-0.9	-1.2	-0.6	-0.6	-1.2	-0.4	-0.5	-0.7	-0.7
Hip circumference	0.4	1.9	5.6	-1.5	-1.4	-2.1	-1.1	-0.5	-1.2	-1.5	-0.7	-1.4	-1.4	-2.1	-1.1	-1.1	-1.3	-0.3	-1.0	-2.4	-1.5	0.7
Father’s age at death	0.4	0.5	3.0	-0.3	-0.1	-1.7	-0.1	-0.4	-0.3	-0.1	-0.9	-0.1	-0.1	-0.3	-0.9	0.1	-0.3	-1.2	-0.3	-0.5	-0.4	-1.5
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.4	3.4	-0.2	-0.2	-1.9	-0.1	0.9	-0.3	-0.2	0.8	-0.3	-0.2	-1.0	0.3	-0.3	-0.2	0.3	-0.0	-0.1	-0.2	1.3
Length of working week for main job	0.4	0.4	1.4	-0.8	-0.8	-0.7	-0.3	0.4	-0.1	-1.0	1.1	-0.7	-0.7	-0.1	0.0	-0.6	-0.5	0.2	0.0	-0.5	-0.6	1.2
Loud music exposure frequency	0.4	0.4	4.5	0.1	-0.0	2.1	0.2	0.2	0.6	-0.2	1.0	0.1	-0.0	0.4	-0.2	-0.2	0.1	-0.9	0.3	0.5	0.0	0.6
Headache pain in last month	0.4	0.7	2.8	0.8	0.8	1.6	0.2	-0.7	0.2	1.1	-1.2	0.7	0.6	0.8	0.6	0.6	0.4	0.9	-0.4	1.7	0.7	-0.7
Medication: Amlodipine	0.4	0.6	2.3	-0.7	-0.7	0.1	-0.3	0.7	0.7	-1.3	1.1	-0.7	-0.4	-1.0	-0.5	-0.0	-0.1	-0.8	0.9	-1.5	-0.5	0.6
Shortness of breath walking on level ground	0.4	0.4	3.0	-0.7	-0.7	-1.7	-0.5	0.4	-0.1	-0.9	0.7	-0.7	-0.6	-0.5	-0.6	-0.1	-0.4	-0.8	-0.0	0.0	-0.4	-0.0
Whole body fat mass	0.4	1.8	25.9	-0.3	-0.3	-5.1	0.2	0.2	0.3	-0.7	0.6	-0.3	-0.2	-1.1	-0.1	0.3	0.0	-0.3	0.5	-0.9	-0.2	2.1
Alcohol intake frequency.	0.4	0.9	4.6	0.9	0.9	2.1	0.8	-0.7	0.8	0.9	-0.2	1.0	0.8	-0.3	0.9	0.8	0.8	-0.6	0.7	0.6	0.8	1.7
Number of full sisters	0.4	0.5	3.9	0.2	0.1	1.1	0.3	0.9	-0.1	0.1	0.5	0.3	0.1	1.1	0.8	0.5	0.2	2.0	0.1	0.1	0.2	0.3
Leg pain on walking	0.4	0.5	3.1	0.0	-0.1	0.7	0.1	1.2	1.0	-0.4	1.8	-0.1	0.1	-0.3	0.3	0.2	0.3	-0.5	0.9	0.4	0.3	1.3
Osteoarthritis (self-reported)	0.4	0.6	3.8	-0.6	-0.5	-1.9	-0.4	0.8	0.1	-0.9	1.5	-0.7	-0.4	-0.3	-0.2	-0.2	-0.0	-1.0	0.7	-0.0	-0.3	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	5.9	0.4	0.4	0.5	-0.5	-1.6	-1.0	1.0	-1.5	0.3	0.1	0.2	-0.3	-0.3	-0.3	0.2	-1.2	1.0	-0.1	-2.4
Arm fat mass (left)	0.4	1.7	18.4	-0.9	-0.9	-4.3	-0.6	-0.2	-0.3	-1.2	0.2	-0.9	-0.9	-1.6	-0.6	-0.5	-0.7	-0.4	-0.2	-1.5	-0.9	1.6
Guilty feelings	0.4	0.6	2.8	0.5	0.5	1.7	0.6	0.6	0.7	0.5	0.9	0.6	0.6	1.1	0.5	0.5	0.6	0.4	0.6	0.8	0.8	0.8
Hearing aid user	0.4	0.4	1.7	-0.0	-0.0	-0.0	0.5	1.1	0.8	-0.4	1.3	0.0	0.2	0.5	0.2	0.4	0.5	-0.6	1.1	0.1	0.2	1.3
Medication: Lisinopril	0.4	0.5	3.0	-0.7	-0.5	0.4	-0.3	0.2	0.1	-1.0	1.2	-0.6	-0.4	-0.9	-0.5	-0.3	-0.1	-1.7	0.6	-0.6	-0.3	0.7
Basal metabolic rate	0.4	2.4	4.9	1.7	1.8	1.3	1.7	1.3	1.0	1.8	1.2	1.8	1.6	1.3	1.9	1.5	1.4	1.8	0.8	1.1	1.6	2.2
Leg fat mass (left)	0.4	1.7	25.4	-0.2	-0.1	-5.0	0.2	0.6	0.3	-0.5	1.0	-0.2	-0.1	-0.7	0.2	0.5	0.1	0.5	0.5	-0.8	-0.1	1.8
Prostate Cancer	0.3	0.4	2.2	-0.1	-0.0	-1.3	-0.2	-0.1	-0.1	0.1	-0.7	-0.1	-0.2	0.8	-0.0	0.4	-0.2	1.5	-0.4	0.1	-0.1	-1.2
Age at First Birth	0.3	0.5	2.4	-0.7	-0.7	1.5	-0.4	-0.4	-0.4	-0.8	-0.2	-0.6	-0.6	-1.0	-0.7	-0.5	-0.5	-1.0	-0.1	-0.5	-0.6	0.1
Hypothyroidism (self reported)	0.3	0.7	4.4	-0.4	-0.6	1.6	-0.2	1.4	-0.2	-0.6	1.1	-0.4	-0.6	0.4	0.4	0.1	-0.5	2.1	-0.5	-0.6	-0.4	-0.4
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	0.8	0.7	-0.1	0.6	0.2	0.2	0.9	-0.4	0.8	0.6	0.8	0.9	0.6	0.5	0.9	0.2	0.8	0.6	0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	-0.4	-0.4	0.2	-0.8	-1.1	-0.7	-0.3	-0.8	-0.5	-0.4	0.1	-0.6	-0.6	-0.5	-1.2	-0.6	0.3	-0.3	-1.0
Diabetes (mother)	0.3	0.4	3.6	-0.1	-0.1	-0.8	0.3	1.3	0.5	-0.4	1.9	-0.1	0.1	-0.3	-0.1	0.4	0.2	0.0	0.8	-0.6	-0.1	0.4
Townsend deprivation index at recruitment	0.3	0.5	3.6	-0.5	-0.5	1.0	-0.4	-0.7	-0.5	-0.5	-0.0	-0.5	-0.5	-0.6	-0.9	-0.6	-0.5	-1.9	-0.4	-0.2	-0.5	0.1
Average weekly fortified wine intake	0.3	0.4	1.6	-0.4	-0.4	-1.3	-0.5	-0.6	-0.5	-0.3	-0.8	-0.5	-0.4	-0.5	-0.3	-0.3	-0.5	0.7	-0.5	-0.9	-0.5	-0.7
Chronic bronchitis/emphysema (father)	0.3	0.4	1.6	-0.6	-0.8	-1.3	-0.4	0.3	-0.3	-0.9	0.4	-0.7	-0.7	-0.1	-0.7	-0.1	-0.6	-0.0	-0.2	-0.3	-0.7	-0.7
Mouth/teeth dental problems	0.3	0.5	4.0	0.3	0.3	-2.0	-0.1	-0.8	-0.8	0.7	-1.5	0.3	0.2	-0.7	0.0	-0.4	-0.1	0.2	-0.8	-0.4	-0.0	-0.4
Heart attack	0.3	0.4	1.4	-0.6	-0.6	0.7	-0.7	-0.6	-0.1	-0.6	-0.3	-0.6	-0.5	-1.2	-0.6	-0.7	-0.5	-0.2	-0.2	-0.9	-0.8	0.5
Weight	0.3	1.4	6.0	1.0	1.1	-2.1	1.2	1.1	0.9	0.8	1.2	1.1	1.0	0.1	1.1	1.2	1.0	0.9	1.0	0.2	1.0	2.5
Time employed in main current job	0.3	0.4	1.1	-0.8	-0.8	-0.2	-0.5	0.2	0.0	-1.0	0.4	-0.8	-0.6	-1.0	-0.2	-0.3	-0.5	0.4	0.0	-1.0	-0.6	0.1
Pulse rate	0.3	0.5	8.1	0.1	0.1	-2.9	0.0	0.4	0.1	0.1	0.8	0.0	0.1	0.4	-0.1	0.4	0.2	0.0	0.1	0.1	0.2	-1.0
Depression (self-reported)	0.3	0.4	1.8	0.2	0.1	1.3	-0.4	-1.3	-0.8	0.5	-1.3	0.0	0.0	0.1	-0.2	-0.5	-0.3	-0.6	-0.7	0.2	-0.2	-0.3
Prospective memory result	0.3	0.4	1.0	-0.6	-0.6	0.3	-0.6	-0.8	-0.6	-0.5	-0.3	-0.6	-0.6	-0.7	-0.7	-0.7	-0.5	-1.0	-0.5	-0.6	-0.5	-0.0
Impedance of arm (left)	0.3	1.2	4.7	-0.5	-0.5	-2.1	-0.6	-1.7	-0.5	-0.5	-2.2	-0.5	-0.4	-1.4	-1.2	-0.7	-0.3	-2.1	-0.2	-0.0	-0.2	-1.3
Hair/balding pattern: Pattern 4	0.3	0.8	3.3	-1.1	-1.2	0.9	-0.5	0.6	0.6	-1.8	0.9	-1.2	-1.0	-0.1	-0.6	-0.5	-0.5	-0.5	0.6	-1.3	-0.9	0.7
Comparative body size at age 10	0.3	0.8	2.3	-0.9	-0.9	-1.5	-0.9	-0.8	-0.3	-0.9	0.5	-0.9	-0.9	-1.4	-1.3	-0.6	-0.9	-0.8	-0.5	-0.4	-1.0	0.2
Age at first live birth	0.3	0.6	1.1	0.9	1.0	0.6	0.7	-0.7	0.8	1.0	-0.8	0.9	0.9	-0.1	0.1	0.6	0.9	-0.7	0.5	0.9	0.9	-0.4
Pulse rate, automated reading	0.3	0.9	5.1	0.7	0.9	-2.3	0.1	-0.3	-0.5	1.2	-0.7	0.7	0.6	0.5	0.2	0.8	0.6	-0.1	-0.3	1.1	1.0	-1.8
Loneliness, isolation	0.3	0.3	2.0	-0.1	-0.2	1.2	-0.0	0.9	-0.3	-0.2	0.8	-0.1	-0.2	1.4	0.6	-0.2	-0.1	1.1	-0.1	-0.2	-0.0	0.2
Diabetes diagnosed by doctor	0.3	0.5	1.5	-0.7	-0.6	-0.6	-0.8	-0.0	-0.8	-0.7	1.1	-0.7	-0.6	-0.4	-0.9	-0.7	-0.5	-1.2	-0.4	-0.5	-0.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.8	0.5	0.6	-0.1	0.6	0.6	0.3	0.5	-0.1	0.5	0.6	0.5	0.8	0.7	0.6	0.8	0.6	0.3	0.5	0.9
Smoking status: Current	0.3	0.5	2.2	-0.7	-0.8	0.6	-0.6	0.0	-1.2	-0.5	0.0	-0.6	-0.8	0.7	0.0	-0.6	-0.8	1.5	-1.1	-0.4	-0.6	-0.3
Ever taken oral contraceptive pill	0.3	0.4	2.2	0.6	0.6	1.5	0.5	0.3	0.6	0.5	0.1	0.5	0.6	-0.5	0.5	0.7	0.7	0.2	0.8	-0.1	0.5	0.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	2.4	-0.4	-0.4	1.3	-0.2	0.1	0.4	-0.7	0.4	-0.4	-0.2	-0.2	-0.5	-0.0	-0.1	-1.6	0.5	-0.4	-0.2	0.7
Eye problems/disorders: Glaucoma	0.3	0.4	1.3	-0.7	-0.7	-1.1	-0.6	-0.5	-0.9	-0.7	0.1	-0.7	-0.7	-0.2	-0.4	-0.3	-0.6	-0.0	-0.4	-0.5	-0.6	-0.5
Impedance of whole body	0.3	1.5	3.6	1.3	1.3	-1.9	1.1	-0.6	0.9	1.3	-1.2	1.3	1.4	0.6	0.5	1.1	1.5	-0.7	1.3	1.7	1.6	-0.6
Major Depression (MDD)	0.2	0.2	2.5	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.3	0.0	0.2	0.0	1.6	0.0
Blood Eosinophil Count	0.2	1.4	4.2	-1.0	-1.1	1.9	-1.3	0.5	-2.1	-0.8	0.6	-1.1	-1.2	0.6	0.1	-0.9	-1.2	1.8	-1.5	-0.8	-0.9	-0.9
Number of treatments/medications taken	0.2	0.4	3.2	0.0	-0.0	-0.7	0.3	0.9	0.4	-0.4	1.4	-0.1	0.2	0.3	0.5	0.1	0.3	-0.1	0.9	-0.4	-0.0	1.8
Medication: Metformin	0.2	0.3	1.3	-0.3	-0.2	-1.0	-0.4	0.0	-0.5	-0.2	1.1	-0.3	-0.2	-0.9	-0.4	-0.3	-0.2	-1.1	-0.2	-0.4	-0.1	0.2
Pack years adult smoking proportion	0.2	0.2	1.1	-0.4	-0.4	0.8	-0.3	0.1	0.3	-0.5	0.9	-0.5	-0.3	0.3	-0.4	-0.3	-0.3	-1.0	0.1	-0.6	-0.4	0.1
Taking other prescription medications	0.2	0.4	1.3	-0.5	-0.6	-1.1	-0.2	0.3	-0.1	-0.8	0.8	-0.5	-0.4	0.2	-0.1	-0.3	-0.3	-0.9	0.1	-0.6	-0.5	1.2
Medication: Levothyroxine sodium	0.2	0.4	3.1	-0.1	-0.2	1.8	-0.1	0.9	-0.1	-0.1	0.7	-0.1	-0.2	0.6	0.5	0.3	-0.2	1.5	-0.2	-0.1	-0.1	-0.3
High blood pressure (mother)	0.2	0.3	2.1	0.2	0.2	-1.5	0.1	0.7	-0.0	0.3	1.0	0.2	0.2	0.4	0.3	0.1	0.1	0.8	-0.1	0.3	-0.0	0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	0.6	0.5	0.6	0.6	0.3	0.6	0.6	-0.1	0.6	0.6	0.3	0.3	0.4	0.5	0.3	0.5	0.2	0.3	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	3.8	-0.1	-0.2	1.3	-0.1	1.1	-0.2	-0.1	0.8	-0.1	-0.3	0.8	0.5	0.2	-0.3	1.9	-0.4	-0.1	-0.2	-0.5
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.9	0.6	0.6	-0.4	0.5	-0.9	-0.2	0.8	-0.7	0.8	0.4	0.3	0.5	0.1	0.2	-0.1	-0.4	0.5	0.4	0.2
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.5	-0.6	-0.6	-0.4	-0.6	0.4	-0.3	-0.7	0.0	-0.7	-0.5	-0.3	-0.2	-0.4	-0.4	-0.4	-0.2	-0.4	-0.3	0.1
High blood pressure (siblings)	0.2	0.3	1.7	0.3	0.2	0.5	0.4	0.4	0.8	0.0	1.3	0.2	0.3	0.5	0.2	0.2	0.4	-0.2	0.7	0.4	0.2	1.3
Wheeze or whistling in the chest in last year	0.2	0.4	2.7	-0.1	-0.1	-1.6	0.1	0.6	0.1	-0.3	1.0	-0.1	-0.0	-0.2	0.4	0.3	0.2	-0.9	0.5	-0.2	0.1	1.4
Medication for pain relief, constipation, heartburn	0.2	0.4	3.3	-0.1	-0.1	1.8	-0.2	-0.8	-0.4	0.1	-1.2	-0.1	-0.1	-0.2	-0.2	-0.2	-0.2	0.0	-0.5	0.1	-0.2	-0.8
Neck or shoulder pain in last month	0.2	0.3	1.8	-0.4	-0.4	1.3	-0.3	0.3	-1.0	-0.2	-0.2	-0.3	-0.6	0.0	0.2	-0.2	-0.6	0.9	-0.9	0.6	-0.3	-0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.9	-0.0	-0.1	-0.3	-0.3	-0.7	-0.0	0.1	-0.9	-0.1	-0.1	0.4	-0.4	-0.2	-0.2	-0.9	-0.4	-0.4	-0.1	-0.9
Supplements: Vitamin C	0.2	0.3	0.9	0.5	0.4	0.9	0.5	-0.1	0.5	0.3	0.2	0.5	0.5	-0.7	0.4	0.2	0.4	-0.5	0.6	-0.0	0.3	1.0
Knee pain experienced in last month	0.2	0.3	1.6	-0.3	-0.3	-0.3	-0.0	0.8	0.4	-0.6	0.8	-0.3	-0.2	0.5	0.6	0.0	0.0	1.2	0.4	-0.3	-0.1	1.2
Average weekly champagne plus white wine intake	0.2	0.3	2.1	-0.1	-0.2	1.5	0.1	-0.0	0.3	-0.5	-0.1	-0.1	-0.1	-0.9	-0.2	-0.3	0.1	-0.8	0.5	-0.6	-0.1	0.7
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.3	-0.5	-0.6	-1.1	-0.3	0.5	0.2	-0.8	0.9	-0.6	-0.4	0.5	-0.2	-0.1	-0.2	0.1	0.3	-0.8	-0.4	0.0
Commuting to job workplace: Cycle	0.2	0.2	0.9	-0.2	-0.3	0.7	0.4	0.3	0.3	-0.6	0.8	-0.1	-0.2	-0.8	-0.2	0.1	0.0	-0.9	0.5	-0.6	0.0	0.6
Pack years of smoking	0.2	0.4	1.6	-0.7	-0.6	0.6	-0.6	-0.1	0.1	-0.7	0.7	-0.7	-0.5	-0.3	-0.6	-0.5	-0.5	-1.3	-0.1	-0.8	-0.6	-0.0
Ovarian Cancer	0.1	0.2	1.5	0.2	0.2	-0.9	0.3	0.3	-0.0	0.2	0.3	0.1	0.4	-0.7	-0.3	0.1	0.1	-1.2	0.3	-0.1	0.1	-0.0
Fasting Glucose	0.1	0.1	0.5	-0.3	-0.5	0.3	-0.3	0.1	0.1	-0.7	0.0	-0.5	-0.3	-0.2	-0.4	-0.4	-0.3	0.1	0.1	-0.7	-0.4	-0.5
Tanning	0.1	1.4	3.7	1.3	1.3	0.2	1.7	0.3	0.7	1.2	0.2	1.5	1.2	1.6	1.3	1.2	1.2	1.9	0.8	1.3	1.2	0.8
Hand grip strength (left)	0.1	0.4	2.1	0.4	0.3	1.4	0.1	-0.3	-0.6	0.7	-0.3	0.4	0.1	0.5	0.1	0.2	-0.1	1.1	-0.8	0.4	0.1	-1.2
Supplements: Zinc	0.1	0.1	0.4	0.3	0.2	-0.5	0.3	0.5	0.3	0.1	0.7	0.3	0.2	-0.0	0.1	0.5	0.2	0.1	0.3	0.3	0.3	-0.4
Leg fat-free mass (left)	0.1	0.3	2.6	0.3	0.4	0.3	0.5	0.4	0.0	0.4	0.6	0.4	0.2	-0.1	0.5	0.2	0.2	0.7	-0.1	-0.3	0.2	1.6
Hand grip strength (right)	0.1	0.4	1.1	0.7	0.6	0.9	0.4	-0.2	-0.4	1.1	-0.3	0.7	0.5	0.5	0.2	0.3	0.2	0.8	-0.6	0.8	0.4	-0.9
Leg predicted mass (left)	0.1	0.3	2.6	0.3	0.4	0.3	0.6	0.4	0.1	0.4	0.5	0.5	0.3	-0.0	0.6	0.2	0.2	0.8	-0.1	-0.3	0.2	1.6
Alcohol intake versus 10 years previously	0.1	0.2	0.7	0.4	0.5	0.3	-0.1	-0.4	-0.2	0.7	-0.4	0.3	0.3	0.1	-0.0	0.5	0.2	0.4	-0.2	0.8	0.3	-0.7
Tense / ‘highly strung’	0.1	0.2	0.5	-0.3	-0.3	0.5	-0.3	-0.5	-0.7	-0.2	-0.1	-0.2	-0.4	0.5	-0.1	-0.4	-0.4	-0.0	-0.6	0.1	-0.2	-0.7
Leg fat-free mass (right)	0.1	0.7	4.3	0.7	0.8	1.5	0.9	0.4	0.3	0.9	0.5	0.9	0.6	0.3	1.0	0.4	0.5	1.0	0.1	0.2	0.6	2.1
Medication: Gliclazide	0.1	0.2	1.4	-0.0	-0.0	0.1	-0.2	0.7	0.1	-0.1	0.8	-0.1	-0.1	-1.2	0.0	-0.1	-0.0	-0.1	0.0	0.2	-0.1	0.5
Leg predicted mass (right)	0.1	0.8	4.2	0.8	0.9	1.6	0.9	0.4	0.3	0.9	0.5	0.9	0.6	0.3	1.1	0.4	0.5	1.0	0.0	0.3	0.6	2.1
Financial situation satisfaction	0.1	0.1	0.6	0.2	0.1	0.5	0.3	0.2	0.2	0.1	0.6	0.2	0.0	0.8	0.0	0.1	-0.0	-0.2	-0.2	0.7	0.1	-0.2
Illnesses of father: High blood pressure	0.1	0.1	1.6	0.1	-0.1	0.3	0.1	0.4	0.3	0.0	1.3	0.1	-0.0	0.5	0.2	0.2	-0.0	0.2	-0.1	0.5	0.0	-0.1
Average weekly beer plus cider intake	0.1	0.2	0.9	0.2	0.1	0.6	0.1	0.4	-0.1	0.3	0.9	0.2	0.1	0.1	-0.3	0.1	-0.0	-0.8	-0.3	0.1	0.2	-0.9
Irritability	0.1	0.2	0.9	-0.5	-0.5	-0.9	-0.1	-0.0	-0.1	-0.7	0.3	-0.4	-0.4	0.0	-0.2	-0.4	-0.3	-0.6	-0.0	-0.4	-0.3	0.6
Ever depressed for a whole week	0.1	0.1	0.9	0.1	0.1	1.0	0.0	0.1	0.4	0.1	0.2	0.0	0.1	0.0	-0.2	-0.2	0.1	-0.8	0.1	-0.3	-0.0	0.1
Unable to work because of sickness or disability	0.1	0.2	1.0	0.1	0.1	0.9	0.0	-0.5	0.1	0.1	-0.2	0.0	0.1	0.4	0.4	-0.5	0.1	-0.4	0.2	0.4	0.2	1.0
Supplements: Calcium	0.1	0.1	0.8	-0.0	-0.2	-0.6	-0.1	0.1	-0.4	0.1	0.1	0.1	-0.3	0.3	0.0	-0.2	-0.4	0.5	-0.7	0.2	-0.2	-0.9
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

SSBP4

Models

Trait associations