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chr16:88,934,149-90,172,696

Best TWAS P=1.67e-11 · Best GWAS P=4.38e-08 conditioned to 0.552

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C16orf3	0.19	0.10	enet	17	0.10	2.7e-12	-5.1	-5.4	5.4e-08	0.71	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	RPL13	0.19	0.03	lasso	2	0.06	3.0e-04	4.0	-5.2	2.2e-07	0.09	0.22	0.15	TRUE
3	GTEx	Adrenal Gland	DBNDD1	0.45	0.24	lasso	9	0.28	1.2e-10	-5.1	-5.4	6.3e-08	0.66	0.01	0.99	FALSE
4	GTEx	Artery Coronary	DBNDD1	0.28	0.19	lasso	2	0.13	3.2e-05	-5.1	-5.3	1.1e-07	0.73	0.01	0.98	FALSE
5	GTEx	Artery Tibial	DBNDD1	0.31	0.20	enet	20	0.27	2.0e-21	-5.1	-5.9	4.4e-09	0.65	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	GAS8	0.60	0.41	lasso	10	0.37	8.0e-12	-5.1	-5.1	2.8e-07	0.71	0.01	0.99	FALSE
7	GTEx	Brain Cortex	GAS8	0.28	0.16	lasso	6	0.14	1.3e-04	-5.1	-5.9	3.9e-09	0.88	0.00	0.99	FALSE
8	GTEx	Brain Cortex	URAHP	0.34	0.19	enet	15	0.17	2.4e-05	-5.1	-5.5	4.9e-08	0.75	0.00	0.98	FALSE
9	GTEx	Breast Mammary Tissue (Male)	SNORD68	0.12	0.00	enet	28	0.03	8.2e-02	-4.4	-6.5	1.1e-10	0.40	0.03	0.19	FALSE
10	GTEx	Cells Transformed fibroblasts	DBNDD1	0.32	0.20	enet	36	0.20	1.2e-14	-5.1	-6.7	1.7e-11	0.68	0.01	0.99	TRUE
11	GTEx	Colon Sigmoid	DBNDD1	0.42	0.13	lasso	5	0.18	7.6e-07	-5.1	-5.6	2.7e-08	0.66	0.01	0.98	FALSE
12	GTEx	Colon Transverse	DBNDD1	0.62	0.40	enet	40	0.44	1.2e-22	-5.1	-6.3	3.6e-10	0.65	0.01	0.99	FALSE
13	GTEx	Esophagus Muscularis	DBNDD1	0.32	0.13	enet	23	0.14	1.2e-08	-5.1	-5.5	3.0e-08	0.55	0.01	0.99	FALSE
14	GTEx	Heart Atrial Appendage	DBNDD1	0.52	0.29	enet	27	0.27	9.8e-13	-5.1	-6.6	3.8e-11	0.67	0.01	0.99	FALSE
15	GTEx	Heart Left Ventricle	DBNDD1	0.24	0.18	lasso	4	0.20	7.6e-11	-5.1	-5.4	8.0e-08	0.66	0.01	0.99	FALSE
16	GTEx	Lung	DBNDD1	0.24	0.14	lasso	6	0.16	1.7e-12	-5.1	-5.6	2.3e-08	0.73	0.01	0.99	FALSE
17	GTEx	Nerve Tibial	DBNDD1	0.25	0.15	lasso	4	0.11	3.3e-08	-5.1	-5.2	2.4e-07	0.71	0.01	0.99	FALSE
18	GTEx	Pancreas	DBNDD1	0.26	0.16	enet	15	0.18	5.6e-08	-5.1	-6.3	2.4e-10	0.58	0.01	0.98	FALSE
19	GTEx	Pancreas	GAS8	0.19	0.08	lasso	4	0.06	1.9e-03	2.8	-5.2	2.2e-07	0.37	0.10	0.62	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	DBNDD1	0.40	0.19	lasso	5	0.19	8.2e-11	-5.1	-6.1	1.1e-09	0.72	0.01	0.99	FALSE
21	GTEx	Skin Not Sun Exposed Suprapubic	URAHP	0.14	0.00	enet	13	0.08	3.1e-05	-1.0	-5.1	2.8e-07	0.27	0.05	0.08	FALSE
22	GTEx	Thyroid	DBNDD1	0.26	0.21	lasso	4	0.20	1.2e-15	-5.1	-5.1	3.1e-07	0.70	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	SPG7	0.13	0.01	blup	59	0.03	5.8e-03	-3.4	-5.2	1.7e-07	0.31	0.00	0.04	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	DPEP1	0.08	0.03	enet	3	0.04	3.2e-05	-4.7	-5.5	4.0e-08	0.91	0.00	0.99	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	FANCA	0.06	0.00	blup	77	0.03	3.7e-03	-4.9	5.3	1.3e-07	-0.36	0.01	0.93	FALSE