[Hub]/) : Traits : Trunk fat-free mass : ← →

chr1:37,628,741-40,737,589

Best TWAS P=4.18e-11 · Best GWAS P=1.01e-11 conditioned to 0.000836

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	SF3A3	0.17	0.12	lasso	4	0.11	2.6e-09	5.16	5.2	2.0e-07	-0.07	0.05	0.95	FALSE
2	GTEx	Adipose Visceral Omentum	FHL3	0.10	0.02	enet	9	0.00	1.9e-01	5.44	5.7	1.1e-08	-0.07	0.05	0.82	FALSE
3	GTEx	Adipose Visceral Omentum	SF3A3	0.20	0.18	lasso	2	0.18	1.5e-09	5.56	5.4	6.5e-08	-0.07	0.03	0.97	FALSE
4	GTEx	Adrenal Gland	PABPC4	0.20	0.09	lasso	8	0.06	3.0e-03	4.70	-5.8	5.6e-09	-0.77	0.05	0.80	FALSE
5	GTEx	Adrenal Gland	FHL3	0.24	0.15	enet	17	0.34	7.4e-13	5.16	6.6	4.2e-11	-0.02	0.01	0.99	TRUE
6	GTEx	Artery Aorta	FHL3	0.35	0.22	lasso	4	0.27	3.9e-15	5.16	6.0	2.3e-09	-0.05	0.01	0.99	FALSE
7	GTEx	Artery Aorta	SF3A3	0.12	0.19	lasso	2	0.18	6.6e-10	5.16	5.2	1.9e-07	-0.08	0.06	0.94	FALSE
8	GTEx	Artery Aorta	INPP5B	0.21	0.13	lasso	3	0.21	5.5e-12	-3.90	5.3	1.1e-07	-0.03	0.11	0.88	FALSE
9	GTEx	Artery Coronary	FHL3	0.31	0.22	lasso	5	0.18	1.3e-06	5.16	5.3	1.4e-07	-0.07	0.04	0.94	FALSE
10	GTEx	Artery Coronary	INPP5B	0.27	0.28	enet	5	0.18	1.4e-06	4.97	5.3	1.4e-07	-0.07	0.05	0.95	FALSE
11	GTEx	Artery Coronary	RP11-109P14.10	0.26	0.10	enet	10	0.00	3.7e-01	5.16	5.6	2.3e-08	-0.07	0.02	0.96	FALSE
12	GTEx	Artery Tibial	FHL3	0.13	0.11	lasso	2	0.13	1.1e-10	5.56	5.8	5.2e-09	-0.06	0.02	0.98	FALSE
13	GTEx	Artery Tibial	SF3A3	0.16	0.11	enet	8	0.12	1.2e-09	5.16	5.3	8.9e-08	-0.06	0.04	0.96	FALSE
14	GTEx	Artery Tibial	UTP11L	0.09	0.14	lasso	3	0.12	1.1e-09	5.56	5.8	8.0e-09	-0.06	0.02	0.98	FALSE
15	GTEx	Breast Mammary Tissue	SF3A3	0.14	0.18	lasso	2	0.16	8.5e-09	5.16	5.3	1.2e-07	-0.08	0.06	0.94	FALSE
16	GTEx	Breast Mammary Tissue (Female)	PABPC4	0.10	0.00	enet	9	0.01	1.5e-01	6.22	-6.1	1.2e-09	-0.83	0.03	0.47	FALSE
17	GTEx	Breast Mammary Tissue (Female)	SF3A3	0.08	0.16	lasso	1	0.10	6.2e-04	5.16	5.2	2.4e-07	-0.08	0.04	0.70	FALSE
18	GTEx	Cells EBV-transformed lymphocytes	SF3A3	0.23	0.11	enet	18	0.09	5.8e-04	5.56	5.8	7.9e-09	-0.05	0.02	0.93	FALSE
19	GTEx	Cells Transformed fibroblasts	FHL3	0.24	0.17	lasso	4	0.15	1.4e-11	5.56	5.6	2.2e-08	-0.06	0.02	0.98	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	SF3A3	0.23	0.11	lasso	6	0.08	7.7e-04	5.56	5.4	6.8e-08	-0.08	0.04	0.94	FALSE
21	GTEx	Esophagus Mucosa	FHL3	0.14	0.14	lasso	5	0.12	3.4e-08	5.56	5.7	1.4e-08	-0.07	0.03	0.97	FALSE
22	GTEx	Esophagus Mucosa	SF3A3	0.08	0.06	lasso	4	0.05	1.5e-04	5.56	5.5	4.0e-08	-0.07	0.04	0.96	FALSE
23	GTEx	Esophagus Mucosa	BMP8A	0.08	0.02	lasso	2	0.01	1.4e-01	-2.48	5.3	1.4e-07	0.69	0.08	0.86	FALSE
24	GTEx	Esophagus Mucosa	PPIEL	0.11	0.02	lasso	3	0.02	9.4e-03	5.72	5.4	5.5e-08	0.76	0.13	0.58	FALSE
25	GTEx	Esophagus Muscularis	SF3A3	0.14	0.03	enet	13	0.06	2.9e-04	5.56	5.4	7.0e-08	-0.10	0.03	0.93	FALSE
26	GTEx	Esophagus Muscularis	RP11-109P14.10	0.17	0.11	lasso	6	0.13	3.6e-08	-4.27	5.2	1.8e-07	-0.03	0.23	0.76	FALSE
27	GTEx	Heart Atrial Appendage	SF3A3	0.15	0.12	lasso	4	0.08	1.4e-04	5.16	5.3	1.1e-07	-0.07	0.05	0.89	FALSE
28	GTEx	Lung	FHL3	0.14	0.07	enet	24	0.13	6.0e-10	5.09	5.3	1.1e-07	-0.01	0.02	0.98	FALSE
29	GTEx	Lung	SF3A3	0.21	0.20	lasso	2	0.21	1.1e-15	5.56	5.4	6.4e-08	-0.07	0.03	0.97	FALSE
30	GTEx	Nerve Tibial	FHL3	0.20	0.12	lasso	7	0.14	1.9e-10	4.97	5.5	3.1e-08	-0.05	0.02	0.98	FALSE
31	GTEx	Nerve Tibial	SF3A3	0.35	0.36	lasso	4	0.35	7.6e-26	5.16	5.2	1.9e-07	-0.07	0.12	0.87	FALSE
32	GTEx	Nerve Tibial	RP11-69E11.8	0.05	0.00	lasso	3	0.01	6.9e-02	4.70	-5.1	2.9e-07	-0.75	0.03	0.86	FALSE
33	GTEx	Ovary	RP11-69E11.4	0.25	0.05	enet	11	0.03	6.7e-02	4.60	5.6	2.7e-08	0.68	0.05	0.43	FALSE
34	GTEx	Pancreas	FHL3	0.17	0.05	lasso	3	0.10	6.6e-05	-5.91	6.1	1.3e-09	0.00	0.00	1.00	FALSE
35	GTEx	Skin Not Sun Exposed Suprapubic	FHL3	0.11	0.11	lasso	4	0.07	1.0e-04	5.40	5.4	5.6e-08	-0.05	0.02	0.97	FALSE
36	GTEx	Skin Not Sun Exposed Suprapubic	SF3A3	0.24	0.14	lasso	4	0.15	1.1e-08	5.16	5.3	1.4e-07	-0.07	0.06	0.94	FALSE
37	GTEx	Skin Sun Exposed Lower leg	RP11-69E11.4	0.13	0.12	lasso	6	0.15	1.3e-12	5.90	5.7	1.4e-08	0.72	0.42	0.58	FALSE
38	GTEx	Skin Sun Exposed Lower leg	FHL3	0.15	0.09	lasso	5	0.10	1.2e-08	-5.91	5.7	1.3e-08	-0.01	0.00	1.00	FALSE
39	GTEx	Spleen	RP11-69E11.4	0.25	0.12	lasso	4	0.15	9.3e-05	4.20	5.5	4.9e-08	0.70	0.19	0.59	FALSE
40	GTEx	Spleen	BMP8A	0.16	0.08	lasso	3	0.05	1.6e-02	5.90	5.2	2.2e-07	0.75	0.07	0.32	FALSE
41	GTEx	Thyroid	SF3A3	0.13	0.16	lasso	2	0.16	1.7e-12	5.16	5.4	7.0e-08	-0.07	0.03	0.97	FALSE
42	METSIM	Adipose	FHL3	0.15	0.12	lasso	5	0.14	6.3e-20	-5.91	5.5	3.2e-08	-0.01	0.00	1.00	FALSE
43	METSIM	Adipose	SF3A3	0.08	0.11	lasso	3	0.11	7.4e-16	5.56	5.6	2.7e-08	-0.07	0.03	0.96	FALSE
44	NTR	Blood	KIAA0754	0.03	0.00	bslmm	366	0.01	1.6e-03	-0.81	5.7	1.1e-08	0.62	0.08	0.78	FALSE
45	NTR	Blood	PABPC4	0.01	0.00	blup	383	0.00	2.8e-02	4.70	-6.6	4.4e-11	-0.68	0.05	0.48	TRUE
46	NTR	Blood	SF3A3	0.10	0.12	lasso	6	0.13	7.2e-39	-5.93	-5.6	2.4e-08	0.01	0.00	1.00	FALSE
47	ROSMAP	Brain Pre-frontal Cortex	FHL3	0.07	0.06	enet	8	0.06	4.9e-08	4.97	5.3	1.3e-07	-0.08	0.06	0.94	FALSE
48	YFS	Blood	SF3A3	0.50	0.29	enet	44	0.44	3.2e-162	5.56	5.5	5.1e-08	0.00	0.02	0.98	FALSE
49	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FHL3	0.08	0.02	enet	7	0.03	1.1e-03	5.16	5.3	9.1e-08	0.02	0.00	0.95	FALSE
50	The Cancer Genome Atlas	Breast Invasive Carcinoma	FHL3	0.06	0.01	enet	10	0.01	4.2e-04	-5.91	5.4	6.9e-08	0.00	0.00	0.99	FALSE
51	The Cancer Genome Atlas	Colon Adenocarcinoma	FHL3	0.10	0.05	lasso	2	0.06	2.9e-04	5.56	6.1	9.5e-10	-0.04	0.00	0.98	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BMP8A	0.04	0.03	blup	48	0.04	3.5e-05	4.20	5.5	4.4e-08	0.68	0.02	0.97	FALSE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	INPP5B	0.05	0.03	blup	68	0.05	6.7e-06	5.09	5.8	5.1e-09	-0.05	0.03	0.96	FALSE
54	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FHL3	0.08	0.08	lasso	2	0.08	1.4e-09	-5.91	5.8	6.4e-09	0.01	0.00	1.00	FALSE
55	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FHL3	0.13	0.03	enet	6	0.05	4.9e-04	-5.91	6.4	1.2e-10	-0.07	0.00	0.94	FALSE
56	The Cancer Genome Atlas	Stomach Adenocarcinoma	FHL3	0.10	0.05	lasso	2	0.03	2.2e-03	-5.91	5.8	9.1e-09	-0.01	0.00	0.96	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	FHL3	0.12	0.03	enet	8	0.03	6.4e-04	4.97	5.5	2.8e-08	-0.06	0.01	0.99	FALSE