[Hub]/) : Traits : Trunk fat-free mass : ← →

chr9:97,520,168-100,366,953

Best TWAS P=1.24e-27 · Best GWAS P=7.32e-33 conditioned to 4.18e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	RP11-435O5.5	0.09	0.04	lasso	2	0.02	7.3e-03	11.20	-10.9	1.2e-27	0.18	0.07	0.74	TRUE
19	The Cancer Genome Atlas	Glioblastoma Multiforme	HABP4	0.08	0.06	blup	44	0.05	1.6e-02	8.76	-9.6	1.2e-21	0.02	0.03	0.52	TRUE
6	GTEx	Cells Transformed fibroblasts	RP11-435O5.5	0.14	0.04	lasso	4	0.02	7.9e-03	6.24	-6.4	1.4e-10	0.14	0.36	0.02	TRUE
14	NTR	Blood	PTCH1	0.04	0.02	blup	433	0.02	4.1e-08	7.54	6.0	2.2e-09	-0.08	0.98	0.00	TRUE
7	GTEx	Heart Atrial Appendage	RP11-435O5.4	0.18	0.00	lasso	5	0.00	6.2e-01	3.12	-5.9	3.2e-09	0.24	0.07	0.16	TRUE
11	GTEx	Spleen	PTCH1	0.33	0.08	lasso	8	0.18	1.9e-05	0.22	5.3	1.0e-07	0.01	0.18	0.06	TRUE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	PTCH1	0.02	0.01	blup	54	0.02	1.1e-03	9.81	-9.8	9.1e-23	0.27	0.04	0.34	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	CDC14B	0.08	0.02	blup	41	0.04	1.0e-03	6.35	-9.5	2.8e-21	0.03	0.02	0.66	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC14B	0.02	0.01	lasso	1	0.01	3.0e-03	9.44	-9.4	3.6e-21	0.02	0.02	0.73	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HABP4	0.02	0.02	blup	44	0.02	7.1e-03	9.26	9.4	3.6e-21	-0.03	0.02	0.76	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC14B	0.03	0.02	blup	42	0.02	2.1e-03	9.26	-9.3	1.0e-20	0.02	0.02	0.79	FALSE
12	GTEx	Testis	HABP4	0.19	0.22	lasso	9	0.21	1.1e-09	9.30	9.3	1.2e-20	-0.02	0.04	0.96	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	CDC14B	0.05	0.07	blup	42	0.08	4.8e-08	9.31	-9.2	5.2e-20	0.03	0.02	0.98	FALSE
15	YFS	Blood	HABP4	0.08	0.09	enet	24	0.11	5.9e-34	9.12	-9.1	6.5e-20	0.03	0.18	0.82	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	HABP4	0.05	0.08	lasso	5	0.08	6.9e-09	8.80	-9.0	2.0e-19	0.01	0.05	0.95	FALSE
13	GTEx	Thyroid	CDC14B	0.15	0.10	lasso	5	0.08	5.3e-07	8.87	-8.9	6.6e-19	-0.03	0.17	0.82	FALSE
10	GTEx	Nerve Tibial	ZNF367	0.10	0.05	lasso	3	0.02	7.9e-03	9.54	8.8	1.6e-18	-0.01	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDC14B	0.05	0.06	lasso	5	0.06	6.5e-07	9.28	-8.7	2.9e-18	0.01	0.03	0.97	FALSE
18	The Cancer Genome Atlas	Glioblastoma Multiforme	CDC14B	0.16	0.17	blup	41	0.19	2.6e-06	9.26	-8.4	3.5e-17	0.02	0.02	0.96	FALSE
16	YFS	Blood	PTCH1	0.09	0.05	lasso	8	0.05	1.2e-15	7.51	8.3	1.1e-16	-0.10	1.00	0.00	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	AAED1	0.17	0.02	lasso	3	0.04	2.4e-02	9.26	8.2	1.9e-16	0.00	0.04	0.62	FALSE
4	GTEx	Breast Mammary Tissue	CDC14B	0.16	0.02	enet	21	0.02	3.7e-02	9.27	-7.9	2.9e-15	-0.01	0.04	0.92	FALSE
1	CommonMind	Brain Pre-frontal Cortex	LOC441454	0.05	0.01	lasso	3	0.02	1.5e-03	6.35	7.3	2.2e-13	0.05	0.03	0.66	FALSE
9	GTEx	Nerve Tibial	HSD17B3	0.14	0.00	enet	20	0.00	2.4e-01	8.96	6.9	5.4e-12	0.01	0.06	0.56	FALSE
8	GTEx	Liver	PTCH1	0.25	0.06	enet	11	0.03	4.9e-02	10.04	6.4	1.5e-10	-0.11	0.16	0.05	FALSE
2	GTEx	Adipose Subcutaneous	HSD17B3	0.21	0.01	enet	31	0.04	1.9e-04	6.63	5.4	7.8e-08	-0.02	0.30	0.25	FALSE