[Hub]/) : Traits : Trunk fat-free mass :

chr1:20,373,107-24,216,118

Best TWAS P=2.5e-14 · Best GWAS P=6.19e-14 conditioned to 0.222

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HTR1D 0.11 0.07 enet 21 0.09 1.1e-10 -5.7 6.5 7.5e-11 -0.78 0.44 0.56 FALSE
2 GTEx Adipose Visceral Omentum LUZP1 0.15 0.08 lasso 7 0.09 1.8e-05 4.0 5.2 2.4e-07 -0.53 0.20 0.32 FALSE
3 GTEx Artery Tibial LUZP1 0.25 0.02 enet 51 0.11 3.4e-09 -6.7 5.2 2.2e-07 -0.45 0.16 0.76 FALSE
4 GTEx Brain Cortex LUZP1 0.23 0.14 lasso 5 0.10 7.8e-04 -7.4 7.4 1.4e-13 -1.00 0.02 0.81 FALSE
5 GTEx Brain Frontal Cortex BA9 RP1-184J9.2 0.38 0.00 lasso 11 0.00 4.3e-01 -7.0 6.1 1.0e-09 -0.54 0.05 0.17 FALSE
6 GTEx Cells Transformed fibroblasts LUZP1 0.09 0.09 lasso 4 0.08 2.8e-06 -7.4 7.4 1.2e-13 -1.00 0.01 0.99 FALSE
7 GTEx Esophagus Muscularis RP1-184J9.2 0.07 0.08 enet 6 0.05 6.1e-04 -5.6 5.5 3.2e-08 -0.72 0.36 0.50 FALSE
8 GTEx Muscle Skeletal LUZP1 0.07 0.08 enet 14 0.08 3.5e-08 4.0 5.9 3.3e-09 -0.62 0.07 0.93 FALSE
9 GTEx Pancreas LINC00339 0.33 0.18 enet 12 0.18 3.5e-08 4.3 -5.4 6.7e-08 -0.01 0.02 0.98 FALSE
10 GTEx Skin Sun Exposed Lower leg KDM1A 0.09 0.01 lasso 5 0.01 1.1e-01 -6.9 -5.5 4.1e-08 0.39 0.11 0.40 FALSE
11 GTEx Testis LUZP1 0.17 0.09 lasso 4 0.08 2.6e-04 -7.0 -7.0 2.4e-12 0.55 0.10 0.66 FALSE
12 GTEx Whole Blood HP1BP3 0.04 0.04 lasso 4 0.02 6.3e-03 -5.1 -5.2 2.2e-07 0.03 0.69 0.09 TRUE
13 METSIM Adipose LUZP1 0.07 0.00 enet 30 0.01 1.1e-02 4.0 5.7 1.2e-08 -0.36 0.12 0.49 TRUE
14 ROSMAP Brain Pre-frontal Cortex CDC42 0.07 0.02 lasso 6 0.04 5.7e-06 3.0 5.5 3.2e-08 0.01 0.10 0.89 TRUE
15 ROSMAP Brain Pre-frontal Cortex HTR1D 0.10 0.10 lasso 4 0.12 1.3e-14 -5.7 5.3 1.4e-07 -0.67 0.88 0.12 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma WNT4 0.03 0.01 blup 72 0.02 3.8e-05 3.5 5.3 1.2e-07 -0.04 0.25 0.50 TRUE
17 The Cancer Genome Atlas Colon Adenocarcinoma HTR1D 0.10 0.07 enet 7 0.08 3.8e-05 -6.8 7.3 2.8e-13 -0.94 0.02 0.98 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma HTR1D 0.24 0.12 lasso 4 0.12 1.2e-05 -7.0 7.6 2.5e-14 -0.76 0.04 0.94 TRUE
19 The Cancer Genome Atlas Rectum Adenocarcinoma HTR1D 0.19 0.12 enet 11 0.13 7.3e-04 -7.5 7.0 2.4e-12 -0.94 0.01 0.91 FALSE