[Hub]/) : Traits : Trunk fat-free mass : ← →

chr1:20,373,107-24,216,118

Best TWAS P=2.5e-14 · Best GWAS P=6.19e-14 conditioned to 0.222

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	HTR1D	0.24	0.12	lasso	4	0.12	1.2e-05	-7.0	7.6	2.5e-14	-0.76	0.04	0.94	TRUE
13	METSIM	Adipose	LUZP1	0.07	0.00	enet	30	0.01	1.1e-02	4.0	5.7	1.2e-08	-0.36	0.12	0.49	TRUE
14	ROSMAP	Brain Pre-frontal Cortex	CDC42	0.07	0.02	lasso	6	0.04	5.7e-06	3.0	5.5	3.2e-08	0.01	0.10	0.89	TRUE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	WNT4	0.03	0.01	blup	72	0.02	3.8e-05	3.5	5.3	1.2e-07	-0.04	0.25	0.50	TRUE
12	GTEx	Whole Blood	HP1BP3	0.04	0.04	lasso	4	0.02	6.3e-03	-5.1	-5.2	2.2e-07	0.03	0.69	0.09	TRUE
6	GTEx	Cells Transformed fibroblasts	LUZP1	0.09	0.09	lasso	4	0.08	2.8e-06	-7.4	7.4	1.2e-13	-1.00	0.01	0.99	FALSE
4	GTEx	Brain Cortex	LUZP1	0.23	0.14	lasso	5	0.10	7.8e-04	-7.4	7.4	1.4e-13	-1.00	0.02	0.81	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	HTR1D	0.10	0.07	enet	7	0.08	3.8e-05	-6.8	7.3	2.8e-13	-0.94	0.02	0.98	FALSE
11	GTEx	Testis	LUZP1	0.17	0.09	lasso	4	0.08	2.6e-04	-7.0	-7.0	2.4e-12	0.55	0.10	0.66	FALSE
19	The Cancer Genome Atlas	Rectum Adenocarcinoma	HTR1D	0.19	0.12	enet	11	0.13	7.3e-04	-7.5	7.0	2.4e-12	-0.94	0.01	0.91	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HTR1D	0.11	0.07	enet	21	0.09	1.1e-10	-5.7	6.5	7.5e-11	-0.78	0.44	0.56	FALSE
5	GTEx	Brain Frontal Cortex BA9	RP1-184J9.2	0.38	0.00	lasso	11	0.00	4.3e-01	-7.0	6.1	1.0e-09	-0.54	0.05	0.17	FALSE
8	GTEx	Muscle Skeletal	LUZP1	0.07	0.08	enet	14	0.08	3.5e-08	4.0	5.9	3.3e-09	-0.62	0.07	0.93	FALSE
7	GTEx	Esophagus Muscularis	RP1-184J9.2	0.07	0.08	enet	6	0.05	6.1e-04	-5.6	5.5	3.2e-08	-0.72	0.36	0.50	FALSE
10	GTEx	Skin Sun Exposed Lower leg	KDM1A	0.09	0.01	lasso	5	0.01	1.1e-01	-6.9	-5.5	4.1e-08	0.39	0.11	0.40	FALSE
9	GTEx	Pancreas	LINC00339	0.33	0.18	enet	12	0.18	3.5e-08	4.3	-5.4	6.7e-08	-0.01	0.02	0.98	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	HTR1D	0.10	0.10	lasso	4	0.12	1.3e-14	-5.7	5.3	1.4e-07	-0.67	0.88	0.12	FALSE
3	GTEx	Artery Tibial	LUZP1	0.25	0.02	enet	51	0.11	3.4e-09	-6.7	5.2	2.2e-07	-0.45	0.16	0.76	FALSE
2	GTEx	Adipose Visceral Omentum	LUZP1	0.15	0.08	lasso	7	0.09	1.8e-05	4.0	5.2	2.4e-07	-0.53	0.20	0.32	FALSE