[Hub]/) : Traits : Trunk fat-free mass :

chr5:41,211,789-44,208,409

Best TWAS P=9.85e-25 · Best GWAS P=8.02e-27 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GHR 0.25 0.07 bslmm 382 0.13 2.6e-15 -7.3 7.3 3.6e-13 0.20 0.97 0.03 FALSE
2 CommonMind Brain Pre-frontal Cortex SEPP1 0.06 0.00 blup 330 0.04 1.9e-05 -2.0 -5.3 1.2e-07 -0.35 0.39 0.03 TRUE
3 GTEx Adipose Subcutaneous CCDC152 0.09 0.04 lasso 4 0.02 6.4e-03 10.0 10.0 1.2e-23 0.46 0.74 0.17 FALSE
4 GTEx Adipose Visceral Omentum CCDC152 0.09 0.06 lasso 9 0.05 1.9e-03 9.9 9.4 7.2e-21 0.45 0.17 0.06 FALSE
5 GTEx Artery Aorta CCDC152 0.31 0.24 lasso 8 0.24 2.5e-13 9.9 9.1 1.2e-19 0.45 0.85 0.15 FALSE
6 GTEx Artery Coronary CCDC152 0.20 0.13 lasso 2 0.12 7.7e-05 9.9 9.9 4.2e-23 0.46 0.59 0.17 FALSE
7 GTEx Artery Tibial CCDC152 0.22 0.17 enet 35 0.18 1.8e-14 9.9 8.0 1.1e-15 0.43 0.85 0.15 FALSE
8 GTEx Brain Caudate basal ganglia C5orf34 0.14 -0.01 enet 14 0.00 3.3e-01 3.5 5.4 5.5e-08 0.07 0.02 0.11 TRUE
9 GTEx Brain Frontal Cortex BA9 GHR 0.14 0.02 lasso 9 0.06 9.9e-03 7.7 -5.7 1.4e-08 -0.31 0.13 0.05 TRUE
10 GTEx Breast Mammary Tissue (Female) SEPP1 0.15 0.00 enet 29 0.02 1.0e-01 -2.3 -5.2 1.5e-07 -0.23 0.07 0.07 TRUE
11 GTEx Esophagus Muscularis CCDC152 0.13 0.09 lasso 8 0.10 7.9e-07 8.8 8.6 7.4e-18 0.48 0.80 0.17 TRUE
12 GTEx Nerve Tibial CCDC152 0.16 0.06 enet 25 0.06 2.9e-05 9.9 6.3 2.3e-10 0.19 0.84 0.10 TRUE
13 GTEx Stomach SERBP1P6 0.12 0.03 enet 16 0.01 6.7e-02 -4.6 7.8 4.4e-15 0.24 0.09 0.09 FALSE
14 GTEx Thyroid CCDC152 0.10 0.07 lasso 4 0.04 4.2e-04 9.9 9.9 3.3e-23 0.45 0.72 0.14 FALSE
15 ROSMAP Brain Pre-frontal Cortex CCDC152 0.20 0.09 lasso 10 0.09 5.2e-12 3.0 6.1 1.1e-09 0.17 1.00 0.00 FALSE
16 ROSMAP Brain Pre-frontal Cortex C5orf51 0.03 0.01 bslmm 298 0.02 1.9e-03 -3.6 5.5 3.1e-08 0.12 0.20 0.37 TRUE
17 ROSMAP Brain Pre-frontal Cortex SEPP1 0.18 0.19 lasso 11 0.21 1.3e-26 9.3 -9.9 4.0e-23 -0.48 0.82 0.18 FALSE
18 YFS Blood CCDC152 0.07 0.06 enet 16 0.06 2.0e-19 10.0 10.3 9.8e-25 0.47 0.80 0.20 TRUE
19 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC152 0.14 0.02 blup 40 0.03 2.5e-06 9.3 -5.5 4.7e-08 -0.38 0.13 0.70 TRUE
20 The Cancer Genome Atlas Breast Invasive Carcinoma SEPP1 0.01 0.00 enet 7 0.01 1.5e-03 9.6 -7.9 4.1e-15 -0.39 0.02 0.56 TRUE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC152 0.06 0.06 blup 40 0.07 1.6e-08 9.2 -10.0 1.5e-23 -0.43 0.03 0.97 FALSE
22 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC152 0.15 0.12 lasso 6 0.12 1.0e-12 9.6 -9.7 4.4e-22 -0.46 0.15 0.85 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma GHR 0.12 0.11 enet 6 0.13 2.5e-13 -7.8 -8.7 2.2e-18 -0.26 1.00 0.00 TRUE
24 The Cancer Genome Atlas Prostate Adenocarcinoma SEPP1 0.06 0.02 blup 38 0.04 5.2e-05 8.8 -9.3 1.2e-20 -0.40 0.13 0.83 FALSE
25 The Cancer Genome Atlas Thyroid Carcinoma MGC42105 0.04 0.01 blup 63 0.01 4.3e-02 -4.1 -5.3 9.7e-08 -0.10 0.00 0.08 TRUE