[Hub]/) : Traits : Trunk predicted mass : ← →

chr16:19,022,448-21,352,507

Best TWAS P=1.58e-11 · Best GWAS P=2.99e-11 conditioned to 4.48e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GPRC5B 0.07 0.04 lasso 4 0.03 1.3e-03 -6.1 6.7 1.6e-11 0.31 0.15 0.63 TRUE
2 GTEx Brain Putamen basal ganglia AC002550.5 0.59 0.48 enet 23 0.58 1.2e-16 -3.8 -5.1 3.0e-07 -0.19 1.00 0.00 FALSE
3 GTEx Cells Transformed fibroblasts THUMPD1 0.13 0.16 enet 16 0.16 4.2e-12 -5.3 -5.5 3.5e-08 0.04 0.02 0.98 TRUE
4 GTEx Esophagus Gastroesophageal Junction KNOP1 0.51 0.44 enet 22 0.56 5.3e-24 -4.6 -5.2 1.7e-07 -0.27 0.87 0.13 FALSE
5 GTEx Esophagus Gastroesophageal Junction AC002550.5 0.62 0.54 enet 35 0.63 4.4e-29 -3.8 -5.3 9.8e-08 -0.27 1.00 0.00 FALSE
6 GTEx Testis AC004381.6 0.18 0.10 lasso 7 0.08 1.8e-04 -5.4 -5.4 5.6e-08 0.04 0.02 0.95 FALSE
7 METSIM Adipose ACSM1 0.05 0.05 lasso 5 0.06 9.5e-09 -5.3 -5.2 2.1e-07 0.05 0.03 0.97 FALSE
8 ROSMAP Brain Pre-frontal Cortex THUMPD1 0.08 0.12 enet 24 0.12 3.0e-15 -5.3 5.2 1.6e-07 -0.03 0.02 0.98 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IQCK 0.03 0.03 lasso 3 0.02 7.2e-04 -5.3 -5.6 2.1e-08 -0.25 0.04 0.91 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma THUMPD1 0.04 0.04 blup 30 0.03 2.3e-03 -5.3 -5.5 4.8e-08 0.03 0.01 0.85 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma ACSM3 0.06 0.06 lasso 13 0.05 2.8e-06 -5.3 5.3 1.2e-07 -0.04 0.01 0.98 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ACSM3 0.06 0.04 blup 43 0.03 5.9e-04 -5.4 5.5 4.0e-08 -0.05 0.01 0.96 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma GPRC5B 0.06 0.01 blup 38 0.01 2.4e-02 -3.8 -6.0 1.8e-09 -0.43 0.01 0.10 FALSE