[Hub]/) : Traits : Trunk predicted mass :

chr20:46,838,455-48,603,940

Best TWAS P=6.54e-14 · Best GWAS P=2.12e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 6.9 -7.1 1.5e-12 -0.82 0.04 0.96 FALSE
2 GTEx Cells Transformed fibroblasts STAU1 0.08 0.03 lasso 6 0.02 2.3e-02 5.9 6.6 5.5e-11 0.85 0.07 0.80 FALSE
3 GTEx Colon Sigmoid ARFGEF2 0.15 0.12 lasso 1 0.07 2.3e-03 5.3 -5.3 9.1e-08 -0.60 0.07 0.52 FALSE
4 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 6.2 -6.3 2.5e-10 -0.80 0.09 0.87 FALSE
5 GTEx Esophagus Mucosa CSE1L 0.09 0.06 lasso 4 0.06 6.9e-05 6.7 -6.2 4.7e-10 -0.80 0.14 0.83 FALSE
6 GTEx Esophagus Mucosa ZFAS1 0.15 0.01 enet 16 0.01 8.9e-02 7.3 5.4 8.2e-08 0.69 0.01 0.95 FALSE
7 GTEx Lung CSE1L 0.10 0.09 lasso 5 0.08 6.6e-07 6.0 -5.9 4.6e-09 -0.73 0.67 0.32 FALSE
8 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 6.8 -6.5 8.2e-11 -0.81 0.35 0.37 FALSE
9 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 5.9 -6.8 8.4e-12 -0.91 0.08 0.92 FALSE
10 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 7.3 -7.5 9.4e-14 -0.98 0.02 0.98 FALSE
11 NTR Blood NCRNA00275 0.07 0.06 lasso 4 0.08 9.7e-25 -4.6 -6.5 9.9e-11 -0.53 1.00 0.00 FALSE
12 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 7.3 -7.5 6.5e-14 -0.96 0.01 0.99 TRUE
13 ROSMAP Brain Pre-frontal Cortex CSE1L 0.04 0.02 enet 16 0.02 2.8e-03 5.3 -5.6 2.8e-08 -0.72 0.08 0.91 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSE1L 0.03 0.05 lasso 1 0.03 9.3e-05 5.9 -5.9 3.1e-09 -0.75 0.08 0.90 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CSE1L 0.05 0.07 blup 50 0.07 3.2e-08 6.2 -6.2 5.0e-10 -0.80 0.05 0.95 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 6.9 -7.4 1.9e-13 -0.94 0.00 1.00 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C20orf199 0.04 0.00 enet 8 0.02 6.4e-03 2.8 5.3 1.4e-07 0.62 0.01 0.50 FALSE
18 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 7.3 7.3 2.9e-13 0.92 0.00 0.96 FALSE
19 The Cancer Genome Atlas Testicular Germ Cell Tumors CSE1L 0.13 0.03 blup 50 0.07 1.4e-03 5.9 -5.7 9.6e-09 -0.60 0.02 0.44 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma DDX27 0.08 0.05 lasso 3 0.05 1.9e-05 7.3 6.4 1.9e-10 0.85 0.01 0.98 FALSE