[Hub]/) : Traits : Relative age of first facial hair : ← →

chr3:49,615,624-52,435,860

Best TWAS P=1.23e-12 · Best GWAS P=1.13e-10 conditioned to 0.404

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	GTEx	Colon Transverse	HEMK1	0.11	0.00	enet	17	0.00	2.0e-01	-4.8	-7.1	1.2e-12	-0.48	0.06	0.39	TRUE
20	GTEx	Esophagus Muscularis	TEX264	0.27	0.21	enet	21	0.27	1.5e-16	6.2	6.1	1.2e-09	0.94	0.02	0.98	TRUE
42	The Cancer Genome Atlas	Glioblastoma Multiforme	RBM6	0.22	0.03	enet	32	0.04	3.1e-02	3.7	-5.2	1.5e-07	-0.14	0.01	0.19	TRUE
34	GTEx	Testis	MANF	0.10	0.07	enet	15	0.11	9.9e-06	6.3	6.5	7.3e-11	0.94	0.03	0.97	FALSE
33	GTEx	Stomach	TEX264	0.09	0.09	lasso	5	0.10	2.4e-05	6.3	6.3	3.5e-10	0.97	0.03	0.97	FALSE
28	GTEx	Nerve Tibial	RP11-804H8.6	0.03	0.03	lasso	6	0.02	2.6e-02	6.0	-6.2	5.6e-10	-0.84	0.08	0.80	FALSE
37	METSIM	Adipose	TEX264	0.07	0.12	lasso	11	0.10	4.7e-15	6.0	6.2	6.0e-10	0.95	0.05	0.95	FALSE
39	ROSMAP	Brain Pre-frontal Cortex	TEX264	0.12	0.16	lasso	12	0.16	2.2e-20	6.0	6.2	7.2e-10	0.93	0.03	0.97	FALSE
26	GTEx	Nerve Tibial	TEX264	0.24	0.31	lasso	4	0.30	8.0e-22	6.0	6.2	7.4e-10	0.96	0.05	0.95	FALSE
18	GTEx	Colon Transverse	TEX264	0.12	0.04	lasso	5	0.06	1.3e-03	6.0	6.1	1.3e-09	0.88	0.08	0.91	FALSE
6	GTEx	Artery Aorta	TEX264	0.10	0.11	lasso	1	0.10	5.8e-06	6.0	6.0	1.6e-09	0.94	0.04	0.96	FALSE
53	The Cancer Genome Atlas	Thyroid Carcinoma	TEX264	0.05	0.08	lasso	2	0.06	1.4e-06	6.0	6.0	1.6e-09	0.94	0.00	1.00	FALSE
8	GTEx	Artery Tibial	TEX264	0.10	0.20	lasso	3	0.19	1.2e-14	6.0	6.0	1.7e-09	0.94	0.08	0.92	FALSE
19	GTEx	Esophagus Mucosa	TEX264	0.10	0.04	lasso	4	0.03	4.5e-03	6.0	6.0	1.8e-09	0.93	0.04	0.93	FALSE
49	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TEX264	0.09	0.05	lasso	3	0.04	1.3e-02	6.0	6.0	1.8e-09	0.93	0.00	0.86	FALSE
9	GTEx	Brain Caudate basal ganglia	HEMK1	0.15	0.12	lasso	9	0.13	1.2e-04	5.5	-6.0	2.2e-09	-0.73	0.08	0.89	FALSE
13	GTEx	Breast Mammary Tissue (Female)	TEX264	0.10	0.17	lasso	3	0.10	6.7e-04	5.9	6.0	2.4e-09	0.94	0.04	0.84	FALSE
14	GTEx	Cells Transformed fibroblasts	HEMK1	0.07	0.06	lasso	6	0.09	5.5e-07	5.3	-5.9	2.9e-09	-0.65	0.14	0.86	FALSE
48	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RAD54L2	0.09	0.02	lasso	3	0.02	2.5e-02	-3.9	-5.9	2.9e-09	-0.63	0.00	0.45	FALSE
41	The Cancer Genome Atlas	Breast Invasive Carcinoma	TEX264	0.01	0.00	lasso	2	0.00	3.7e-02	5.9	5.9	3.4e-09	0.92	0.00	0.84	FALSE
31	GTEx	Spleen	TEX264	0.24	0.12	lasso	5	0.12	6.6e-04	6.0	5.9	3.5e-09	0.91	0.03	0.83	FALSE
5	GTEx	Adipose Visceral Omentum	TEX264	0.15	0.15	lasso	2	0.12	8.4e-07	6.0	5.9	3.9e-09	0.92	0.07	0.93	FALSE
15	GTEx	Colon Sigmoid	TEX264	0.15	0.10	lasso	3	0.09	3.1e-04	5.6	5.8	4.9e-09	0.87	0.06	0.81	FALSE
50	The Cancer Genome Atlas	Prostate Adenocarcinoma	TEX264	0.03	0.04	lasso	2	0.03	2.8e-04	6.0	5.8	6.1e-09	0.91	0.00	0.99	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C3orf18	0.02	0.02	blup	28	0.02	8.1e-04	5.4	5.8	8.1e-09	0.73	0.01	0.92	FALSE
16	GTEx	Colon Transverse	C3orf18	0.04	0.01	lasso	4	0.00	1.8e-01	5.6	5.8	8.3e-09	0.66	0.14	0.55	FALSE
12	GTEx	Breast Mammary Tissue	TEX264	0.11	0.10	lasso	5	0.08	6.2e-05	5.6	5.7	9.6e-09	0.90	0.06	0.91	FALSE
36	GTEx	Whole Blood	MAPKAPK3	0.08	0.04	lasso	3	0.01	2.4e-02	5.8	-5.7	1.0e-08	-0.78	0.12	0.84	FALSE
44	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DOCK3	0.02	0.01	blup	237	0.02	3.1e-03	4.9	5.7	1.2e-08	0.81	0.13	0.66	FALSE
38	ROSMAP	Brain Pre-frontal Cortex	HEMK1	0.07	0.13	lasso	5	0.13	7.9e-16	5.3	-5.7	1.4e-08	-0.72	0.50	0.50	FALSE
24	GTEx	Lung	TEX264	0.08	0.06	lasso	5	0.07	1.0e-05	5.9	5.7	1.6e-08	0.89	0.06	0.94	FALSE
35	GTEx	Thyroid	TEX264	0.07	0.06	enet	10	0.08	1.9e-06	5.6	5.6	1.7e-08	0.90	0.06	0.93	FALSE
23	GTEx	Lung	HEMK1	0.03	0.01	enet	17	0.00	3.0e-01	5.9	-5.6	2.1e-08	-0.52	0.08	0.66	FALSE
2	CommonMind	Brain Pre-frontal Cortex	HEMK1	0.04	0.05	lasso	3	0.05	2.6e-06	5.1	-5.6	2.2e-08	-0.75	0.15	0.85	FALSE
27	GTEx	Nerve Tibial	SEMA3B-AS1	0.25	0.04	lasso	5	0.03	3.3e-03	5.6	5.6	2.4e-08	0.60	0.13	0.85	FALSE
32	GTEx	Spleen	XXcos-LUCA11.4	0.10	0.08	lasso	5	0.02	9.0e-02	5.3	5.5	3.1e-08	0.73	0.07	0.66	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	HEMK1	0.02	0.02	lasso	2	0.02	1.0e-04	5.6	-5.5	3.2e-08	-0.74	0.03	0.95	FALSE
11	GTEx	Brain Putamen basal ganglia	SEMA3B-AS1	0.18	0.05	lasso	7	0.03	6.0e-02	5.6	5.5	3.8e-08	0.63	0.05	0.63	FALSE
22	GTEx	Heart Left Ventricle	C3orf18	0.06	0.05	lasso	4	0.04	2.6e-03	5.3	5.5	3.8e-08	0.74	0.11	0.86	FALSE
51	The Cancer Genome Atlas	Rectum Adenocarcinoma	HEMK1	0.14	0.08	blup	28	0.06	1.6e-02	5.5	-5.5	4.6e-08	-0.73	0.01	0.35	FALSE
3	GTEx	Adipose Subcutaneous	TEX264	0.22	0.17	enet	20	0.20	2.5e-16	6.0	5.5	5.1e-08	0.88	0.03	0.97	FALSE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HEMK1	0.01	0.00	blup	29	0.01	1.6e-02	5.2	-5.4	5.4e-08	-0.71	0.02	0.73	FALSE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	HEMK1	0.57	0.03	lasso	6	0.02	2.4e-02	6.0	-5.4	5.9e-08	-0.73	0.00	0.87	FALSE
25	GTEx	Nerve Tibial	HEMK1	0.09	0.13	lasso	7	0.12	8.3e-09	5.3	-5.4	6.4e-08	-0.75	0.15	0.85	FALSE
30	GTEx	Small Intestine Terminal Ileum	HYAL3	0.22	0.17	enet	12	0.10	2.6e-03	-5.3	-5.4	6.6e-08	-0.11	0.09	0.17	FALSE
4	GTEx	Adipose Visceral Omentum	HEMK1	0.07	0.05	lasso	3	0.04	3.2e-03	5.3	-5.4	7.2e-08	-0.74	0.11	0.69	FALSE
52	The Cancer Genome Atlas	Thyroid Carcinoma	HEMK1	0.06	0.08	lasso	2	0.07	1.3e-07	5.4	-5.3	8.7e-08	-0.74	0.09	0.91	FALSE
21	GTEx	Heart Atrial Appendage	HEMK1	0.15	0.10	lasso	5	0.06	1.2e-03	5.1	-5.3	9.0e-08	-0.59	0.19	0.71	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C3orf18	0.03	0.02	blup	265	0.03	2.1e-04	5.2	5.3	1.4e-07	0.72	0.13	0.84	FALSE
7	GTEx	Artery Tibial	HEMK1	0.03	0.03	enet	3	0.02	7.1e-03	5.1	-5.2	1.6e-07	-0.73	0.21	0.70	FALSE
10	GTEx	Brain Cerebellum	HEMK1	0.14	0.10	lasso	3	0.07	5.2e-03	5.3	-5.2	1.9e-07	-0.73	0.06	0.41	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	HEMK1	0.04	0.06	blup	31	0.07	4.4e-08	5.5	-5.2	1.9e-07	-0.74	0.05	0.95	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	CYB561D2	0.08	0.01	enet	7	0.02	2.3e-02	2.5	-5.2	2.6e-07	-0.41	0.10	0.61	FALSE