TWAS hub - HEMK1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0210	4.9e-06	0.051	0.045	0.027	0.044	0.046	7.9e-07	3.0e-06	2.7e-04	3.7e-06	2.6e-06
2	GTEx	Adipose Visceral Omentum	0.0650	0.0420	5.5e-03	0.054	NA	0.015	NA	0.041	8.3e-04	NA	5.6e-02	NA	3.2e-03
3	GTEx	Artery Tibial	0.0296	0.0155	2.6e-03	0.032	NA	0.022	NA	0.021	1.4e-03	NA	7.1e-03	NA	8.9e-03
4	GTEx	Brain Caudate basal ganglia	0.1530	0.0650	4.3e-05	0.118	NA	0.118	NA	0.133	2.9e-04	NA	3.0e-04	NA	1.2e-04
5	GTEx	Brain Cerebellum	0.1360	0.0780	6.7e-03	0.105	NA	0.042	NA	0.066	5.1e-04	NA	2.2e-02	NA	5.2e-03
6	GTEx	Brain Cortex	0.1630	0.0790	2.1e-03	0.015	NA	0.027	NA	0.010	1.2e-01	NA	6.1e-02	NA	1.7e-01
7	GTEx	Breast Mammary Tissue (Female)	0.0914	0.0838	1.2e-01	-0.004	NA	-0.008	NA	-0.005	4.6e-01	NA	6.9e-01	NA	4.9e-01
8	GTEx	Cells Transformed fibroblasts	0.0670	0.0310	4.6e-06	0.064	NA	0.079	NA	0.086	1.5e-05	NA	1.6e-06	NA	5.5e-07
9	GTEx	Colon Sigmoid	0.0780	0.0410	2.0e-03	0.079	NA	0.063	NA	0.065	9.7e-04	NA	2.9e-03	NA	2.6e-03
10	GTEx	Colon Transverse	0.1130	0.0700	9.2e-03	0.000	NA	0.004	NA	-0.001	3.2e-01	NA	2.0e-01	NA	3.6e-01
11	GTEx	Esophagus Gastroesophageal Junction	0.1850	0.0790	1.2e-03	-0.007	NA	-0.007	NA	-0.008	7.5e-01	NA	7.4e-01	NA	8.8e-01
12	GTEx	Heart Atrial Appendage	0.1470	0.0780	3.5e-04	0.105	NA	0.051	NA	0.059	1.9e-05	NA	2.5e-03	NA	1.2e-03
13	GTEx	Lung	0.0311	0.0192	6.8e-03	0.009	NA	0.000	NA	-0.002	6.3e-02	NA	3.0e-01	NA	4.9e-01
14	GTEx	Muscle Skeletal	0.1195	0.0625	1.2e-05	0.006	NA	0.027	NA	0.020	7.2e-02	NA	9.4e-04	NA	4.3e-03
15	GTEx	Nerve Tibial	0.0935	0.0445	2.0e-06	0.130	NA	0.091	NA	0.120	1.9e-09	NA	5.2e-07	NA	8.3e-09
16	ROSMAP	Brain Pre-frontal Cortex	0.0669	0.0273	1.5e-12	0.127	0.105	0.122	0.113	0.126	5.6e-16	2.0e-13	1.9e-15	2.7e-14	7.9e-16
17	TCGA	Breast Invasive Carcinoma	0.0203	0.0146	2.1e-04	0.019	0.015	0.004	NA	0.018	5.5e-05	3.7e-04	3.5e-02	NA	1.0e-04
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0142	0.0090	5.2e-03	0.005	0.012	0.004	NA	0.004	8.1e-02	1.6e-02	1.2e-01	NA	1.0e-01
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.5670	0.1270	4.6e-05	0.027	0.005	0.008	NA	0.020	1.1e-02	1.6e-01	1.1e-01	NA	2.4e-02
20	TCGA	Brain Lower Grade Glioma	0.0399	0.0175	6.4e-08	0.056	0.067	0.061	NA	0.062	5.1e-07	4.4e-08	1.6e-07	NA	1.3e-07
21	TCGA	Prostate Adenocarcinoma	0.0530	0.0269	3.4e-06	0.059	0.047	0.047	NA	0.049	8.4e-07	9.9e-06	1.0e-05	NA	6.6e-06
22	TCGA	Rectum Adenocarcinoma	0.1380	0.0940	8.3e-03	0.076	0.060	0.025	NA	0.058	7.6e-03	1.6e-02	8.8e-02	NA	1.8e-02
23	TCGA	Thyroid Carcinoma	0.0570	0.0300	1.6e-06	0.076	0.062	0.072	NA	0.073	6.6e-08	1.2e-06	1.5e-07	NA	1.3e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	12	13	14	15	16	17	18	19	20	21	22	23
Impedance of leg (right)	15.9	77.2	176.9	-9.6	-9.8	-9.7	-9.2	-9.8	-13.3	-0.1	-10.3	-7.4	-2.2	-9.1	-6.8	-5.3	-9.8	-9.9	-9.4	-8.8	-9.1	-9.8	-10.1	-8.6	-9.9
Impedance of leg (left)	13.9	67.5	163.8	-8.9	-9.2	-9.2	-8.6	-9.1	-12.8	-0.1	-9.7	-6.8	-1.4	-8.8	-6.0	-4.7	-9.1	-9.2	-8.8	-8.1	-8.5	-9.2	-9.4	-8.1	-9.2
Relative age of first facial hair	12.9	26.5	50.4	-5.6	-5.4	-5.2	-6.0	-5.2	-4.0	0.1	-5.9	-4.1	-7.1	-5.3	-5.6	-4.3	-5.4	-5.7	-5.5	-5.4	-5.4	-5.2	-5.1	-5.5	-5.3
Impedance of whole body	12.4	63.1	166.4	-8.6	-9.0	-8.9	-8.0	-8.9	-12.9	-0.4	-9.5	-6.6	-0.6	-8.1	-5.2	-4.3	-8.9	-8.8	-8.4	-7.6	-8.5	-8.8	-9.3	-7.6	-9.0
Age when periods started (menarche)	12.0	28.8	47.3	-6.0	-5.9	-5.9	-5.9	-5.7	-3.7	0.4	-6.9	-4.8	-6.0	-5.7	-4.6	-4.1	-5.9	-6.1	-5.8	-5.8	-5.7	-5.8	-5.8	-5.3	-5.9
Chronotype (morning person)	10.4	24.1	50.1	5.1	5.0	5.2	5.4	4.9	5.4	1.1	7.1	3.8	5.1	4.7	6.7	3.5	5.0	5.2	5.2	5.4	4.1	5.0	5.0	4.6	5.1
Time employed in main current job	9.4	10.8	15.3	3.8	3.8	3.7	3.9	3.7	2.9	-0.2	3.2	2.7	2.7	2.6	2.9	2.4	3.8	3.6	3.9	3.6	3.6	3.6	3.7	3.8	3.8
Impedance of arm (right)	9.1	42.4	125.4	-6.9	-7.5	-7.3	-6.3	-7.4	-11.2	-0.8	-8.1	-5.3	0.3	-6.2	-3.8	-3.8	-7.4	-7.0	-6.9	-6.1	-6.8	-7.1	-7.7	-6.0	-7.4
Forced expiratory volume in 1-second (FEV1), predicted	8.3	17.3	24.6	-4.4	-4.4	-4.6	-4.8	-4.3	-4.9	0.0	-5.0	-3.4	-3.5	-4.4	-3.5	-3.5	-4.5	-4.7	-4.8	-4.6	-3.2	-4.5	-4.4	-4.9	-4.5
Alcohol drinker status: Previous	8.2	9.3	19.4	3.1	3.4	3.3	3.4	3.4	4.4	0.4	3.6	2.5	1.1	3.1	2.5	2.8	3.3	3.2	3.4	3.2	2.4	3.3	3.2	3.6	3.3
Height	8.0	153.9	210.2	-13.5	-13.8	-14.2	-14.2	-13.7	-13.9	0.9	-13.5	-9.8	-9.2	-12.9	-9.1	-9.5	-13.9	-14.1	-14.5	-13.4	-11.9	-13.2	-13.6	-14.3	-13.9
Impedance of arm (left)	8.0	37.2	110.2	-6.6	-7.0	-6.9	-5.8	-6.9	-10.5	-0.7	-7.5	-5.0	0.2	-5.8	-3.5	-3.3	-6.9	-6.6	-6.4	-5.6	-6.6	-6.6	-7.3	-5.6	-7.0
Commuting to job workplace: Public transport	7.9	9.4	14.8	3.4	3.4	3.5	3.4	3.4	2.5	0.4	3.0	2.9	2.5	3.1	2.4	3.1	3.3	3.4	3.6	3.7	2.3	3.6	3.2	3.8	3.4
Relative age voice broke	7.5	11.4	18.5	-3.9	-3.7	-3.6	-3.7	-3.6	-2.7	-0.2	-4.3	-2.4	-4.3	-3.5	-3.3	-2.1	-3.7	-3.7	-3.5	-3.3	-4.0	-3.5	-3.5	-3.6	-3.6
Blood Eosinophil Count	6.9	53.4	99.8	-9.0	-7.5	-7.1	-9.1	-7.1	-4.7	-0.3	-7.1	-6.5	-10.0	-5.6	-7.7	-9.0	-7.6	-7.1	-7.8	-7.5	-8.7	-6.9	-6.8	-8.8	-7.2
Had menopause	6.9	8.7	14.7	2.9	3.5	3.4	3.0	3.6	3.7	-0.0	2.7	2.5	0.2	3.4	2.2	1.6	3.4	3.8	3.4	3.1	2.2	3.4	3.6	3.0	3.6
Standing height	6.8	67.4	91.0	-8.8	-9.2	-9.5	-9.4	-9.1	-9.1	0.3	-9.1	-6.5	-5.7	-8.4	-6.1	-5.9	-9.2	-9.3	-9.5	-8.8	-8.0	-8.8	-9.1	-9.5	-9.2
Ever highly irritable/argumentative for 2 days	6.4	7.6	19.6	-2.9	-2.8	-2.9	-3.2	-2.9	-1.7	0.2	-2.8	-2.8	-3.2	-3.0	-4.4	-2.1	-2.8	-2.9	-2.8	-3.2	-2.5	-2.9	-2.6	-2.7	-2.8
Comparative body size at age 10	5.6	15.5	40.6	3.8	4.3	4.7	4.3	4.3	6.4	0.0	3.8	3.6	0.1	4.5	3.0	2.1	4.3	4.5	4.2	4.4	3.7	4.5	4.4	3.6	4.4
Commuting to job workplace: Walk	5.3	5.8	9.6	2.5	2.6	2.8	2.5	2.8	1.6	-0.0	2.6	1.7	3.1	2.8	2.2	1.8	2.6	2.7	2.8	2.7	1.7	2.7	2.7	2.7	2.7
Lung FVC	5.1	25.8	36.2	5.6	5.6	5.6	5.6	5.7	5.4	-0.3	5.1	5.1	2.5	6.0	4.3	4.3	5.6	6.0	5.5	5.3	5.1	5.6	5.6	5.1	5.6
Taking other prescription medications	5.0	7.7	17.4	-2.8	-2.8	-2.8	-3.7	-2.6	-1.4	0.1	-2.5	-2.6	-3.3	-3.0	-4.2	-2.6	-2.7	-2.9	-2.9	-3.1	-2.7	-2.8	-2.3	-3.4	-2.6
Frequency of unenthusiasm / disinterest in last 2 weeks	4.9	6.5	17.6	-2.5	-2.5	-2.8	-2.7	-2.5	-2.9	-0.2	-2.9	-1.6	-2.6	-3.0	-4.2	-2.2	-2.5	-2.8	-2.5	-2.5	-2.2	-2.7	-2.5	-2.5	-2.5
Ever depressed for a whole week	4.8	5.9	19.2	-2.6	-2.3	-2.5	-2.7	-2.4	-1.8	0.2	-2.9	-2.1	-4.4	-2.3	-3.5	-2.0	-2.3	-2.4	-2.3	-2.7	-2.2	-2.4	-2.2	-2.0	-2.3
Length of working week for main job	4.4	4.9	8.2	2.9	2.5	2.5	2.5	2.5	1.6	0.3	2.8	1.1	2.3	1.9	1.5	1.9	2.5	2.4	2.5	2.0	2.8	2.0	2.5	2.4	2.5
Tense / ‘highly strung’	4.4	7.2	13.6	-2.2	-2.7	-2.9	-2.8	-2.8	-3.7	0.4	-3.1	-1.6	-1.6	-3.5	-3.5	-3.0	-2.6	-3.2	-2.9	-2.9	-1.3	-3.0	-2.6	-2.9	-2.8
Leg pain on walking	4.4	5.5	11.2	-2.3	-2.4	-2.3	-3.0	-2.4	-0.5	0.2	-2.3	-3.4	-2.1	-2.4	-2.0	-1.9	-2.4	-2.6	-2.6	-3.1	-2.5	-2.8	-2.1	-2.5	-2.4
BMI	4.3	24.7	98.2	5.3	5.5	5.3	4.7	5.4	9.9	-0.7	6.7	3.8	0.7	4.3	1.5	2.3	5.5	5.1	5.2	4.7	5.3	5.4	5.8	4.4	5.5
Health satisfaction	4.3	5.6	14.3	-2.2	-2.2	-2.4	-3.0	-2.2	-2.3	-0.2	-2.6	-2.3	-1.7	-2.4	-3.8	-2.6	-2.2	-2.5	-2.6	-2.7	-1.7	-2.5	-2.1	-2.9	-2.3
Overall health rating	4.3	9.2	18.6	-3.0	-3.2	-3.3	-3.5	-3.3	-2.1	-0.0	-3.0	-3.1	-2.4	-3.4	-4.3	-2.7	-3.2	-3.5	-3.3	-3.5	-2.3	-3.4	-3.1	-3.3	-3.2
Family relationship satisfaction	4.3	5.3	8.7	-2.1	-2.2	-2.4	-2.7	-2.2	-2.4	-0.3	-2.4	-2.6	-2.1	-2.6	-2.8	-3.0	-2.2	-2.5	-2.3	-2.8	-2.0	-2.5	-2.2	-2.0	-2.2
Pack years of smoking	4.3	6.4	16.3	2.5	2.6	2.6	2.5	2.6	4.0	0.1	3.8	1.6	1.9	4.0	1.6	2.4	2.5	3.0	2.3	2.1	2.1	2.3	2.6	2.1	2.5
Body mass index (BMI)	4.2	18.0	71.7	4.7	4.7	4.6	3.9	4.6	8.5	-0.0	6.1	2.8	0.9	3.7	1.2	1.7	4.7	4.2	4.4	3.8	4.7	4.5	5.0	3.7	4.7
Depression (Nagel 2018)	4.1	6.2	14.3	-2.5	-2.6	-2.6	-2.7	-2.6	-3.2	-0.2	-3.6	-1.1	-2.7	-2.9	-3.8	-1.8	-2.5	-2.7	-2.4	-2.2	-2.0	-2.4	-2.4	-2.3	-2.4
Waist Hip Ratio (WHR)	4.0	18.0	34.9	-4.8	-4.6	-4.6	-4.9	-4.5	-5.9	1.2	-4.9	-2.5	-4.0	-4.3	-4.2	-2.7	-4.5	-4.7	-4.5	-3.9	-4.4	-4.4	-4.5	-4.6	-4.5
Financial situation satisfaction	3.8	4.7	10.6	-2.1	-2.1	-2.5	-2.6	-2.0	-1.5	-0.4	-2.2	-2.1	-2.2	-2.9	-3.3	-1.7	-2.1	-2.5	-2.1	-2.3	-2.0	-2.4	-2.0	-2.4	-2.1
Alcohol intake versus 10 years previously	3.7	5.6	9.9	-2.4	-2.4	-2.5	-2.8	-2.5	-1.3	0.0	-2.7	-2.2	-2.5	-3.2	-2.9	-1.9	-2.4	-2.8	-2.5	-2.4	-2.3	-2.4	-2.4	-2.4	-2.5
Pack years adult smoking proportion	3.6	5.5	14.4	2.4	2.3	2.5	2.3	2.4	3.8	0.0	3.8	1.1	2.1	3.8	1.2	2.2	2.3	2.7	2.1	1.9	1.9	2.1	2.4	2.0	2.2
Ever unenthusiastic/disinterested for a whole week	3.6	4.4	16.9	-1.8	-1.8	-2.2	-2.1	-1.7	-1.8	-0.0	-3.0	-1.0	-3.9	-2.8	-4.1	-0.7	-1.8	-2.1	-1.6	-2.0	-1.6	-1.9	-1.7	-1.4	-1.7
Hayfever/allergic rhinitis (self-reported)	3.5	4.6	8.3	-2.2	-2.2	-2.2	-2.6	-2.2	-2.9	0.2	-2.3	-2.0	-1.3	-2.8	-1.7	-2.1	-2.2	-2.5	-2.3	-2.0	-2.1	-2.1	-2.0	-2.7	-2.1
Birth weight of first child	3.5	6.3	9.7	2.4	2.8	2.9	2.8	2.9	3.1	0.2	2.3	3.0	-0.1	2.7	1.9	2.1	2.7	2.9	2.8	3.0	2.2	3.1	2.9	2.4	2.8
Qualifications: CSEs or equivalent	3.4	4.4	8.7	-2.2	-2.2	-2.1	-2.4	-2.2	-1.0	-0.3	-1.7	-3.0	-2.7	-2.5	-1.9	-1.2	-2.3	-2.5	-2.3	-2.4	-2.1	-2.3	-2.2	-1.9	-2.3
Number of incorrect matches in round	3.4	5.7	9.7	2.8	2.7	2.8	2.2	2.8	2.7	-0.2	3.1	0.5	2.3	2.6	2.8	-0.6	2.7	2.8	2.4	1.8	2.6	2.5	2.9	2.3	2.7
Mean time to correctly identify matches	3.4	6.5	16.1	2.7	2.8	2.9	3.2	2.6	2.2	-0.3	1.9	2.2	1.5	4.0	2.1	2.3	2.7	3.1	2.8	2.9	2.5	2.7	2.6	2.8	2.7
Body Mass Index (BMI) (2010)	3.2	4.4	12.6	2.1	2.5	2.5	2.1	2.5	3.6	0.2	2.0	1.9	-0.2	1.9	1.2	1.5	2.4	2.2	2.3	2.3	1.9	2.4	2.3	2.3	2.4
Nervous feelings	3.2	5.9	16.9	-2.2	-2.2	-2.3	-2.7	-2.3	-4.1	-0.1	-3.2	-0.9	-2.4	-3.1	-3.4	-2.4	-2.1	-2.6	-2.5	-2.1	-1.0	-2.3	-2.1	-3.1	-2.2
Qualifications: College or University degree	3.2	10.1	15.1	3.5	3.3	3.3	3.7	3.4	-0.7	-0.5	2.9	3.9	3.8	3.1	3.0	3.6	3.4	3.6	3.4	3.6	3.6	3.3	3.1	3.4	3.3
Ulcerative Colitis	3.0	4.3	8.9	2.0	2.0	2.1	2.5	2.0	1.4	0.6	3.0	2.4	1.6	2.0	1.9	2.5	2.0	2.3	2.3	2.7	1.9	2.4	1.9	2.1	2.1
Wheeze or whistling in the chest in last year	3.0	5.4	11.2	-2.2	-2.2	-2.1	-3.3	-2.0	-0.8	-0.5	-1.1	-3.2	-1.5	-2.1	-3.3	-3.1	-2.3	-2.4	-2.6	-2.9	-2.0	-2.4	-1.9	-3.2	-2.2
Breast Cancer	2.9	7.1	10.1	3.0	3.0	2.9	3.0	3.0	2.1	1.3	3.2	1.9	2.0	2.1	2.9	1.7	3.0	2.7	3.0	2.7	3.1	2.9	3.1	3.0	3.0
Falls in the last year	2.9	3.9	9.7	2.1	2.3	2.3	1.8	2.5	3.1	-0.0	1.5	1.4	-0.8	2.1	1.0	1.0	2.3	2.4	2.4	2.0	1.3	2.2	2.6	2.0	2.5
Back pain experienced in last month	2.9	4.2	9.8	-2.0	-2.1	-2.0	-2.1	-2.1	-1.7	-0.7	-1.9	-3.1	-0.9	-1.8	-2.1	-2.8	-2.1	-2.1	-2.2	-2.5	-1.8	-2.5	-2.2	-1.9	-2.1
Allergy	2.8	6.5	14.8	2.6	2.2	2.2	3.7	1.8	2.3	0.5	2.2	3.0	2.9	2.3	3.7	3.8	2.2	2.2	2.6	2.8	2.5	2.1	1.7	3.5	2.0
Age started oral contraceptive pill	2.8	3.5	5.3	1.6	1.9	1.9	2.2	2.1	1.0	0.1	1.1	2.3	1.5	2.3	2.2	1.6	2.0	2.3	2.2	2.2	1.5	2.2	2.0	2.2	2.0
Commuting to job workplace: Cycle	2.8	3.3	7.7	1.9	2.1	2.0	1.8	2.1	1.4	-0.1	1.4	2.8	0.9	0.9	2.1	1.1	2.1	1.8	2.3	2.6	1.3	2.2	2.1	1.8	2.1
Lupus	2.7	4.1	8.8	-2.5	-2.0	-2.0	-2.5	-1.8	-0.6	-1.0	-3.0	-2.0	-3.0	-2.2	-1.5	-1.3	-2.1	-2.2	-2.2	-2.2	-1.9	-2.0	-2.0	-2.3	-1.9
Hayfever, allergic rhinitis or eczema	2.7	5.9	11.6	-2.5	-2.4	-2.4	-3.1	-2.1	-3.2	-0.2	-2.2	-3.1	-1.0	-2.5	-2.6	-3.4	-2.3	-2.4	-2.5	-2.7	-2.5	-2.4	-2.1	-3.0	-2.2
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.3	12.3	-1.8	-1.9	-2.1	-2.2	-1.9	-2.7	-0.3	-3.5	-2.6	-1.1	-2.2	-2.9	-1.0	-1.9	-2.1	-2.0	-2.5	-1.5	-2.4	-1.9	-1.8	-1.9
Angina (self-reported)	2.7	3.6	8.8	2.4	2.0	1.8	1.9	1.9	2.1	0.7	2.2	1.5	3.0	0.9	2.1	0.9	2.1	1.6	2.1	1.6	2.1	1.8	2.1	2.3	2.0
Commuting to job workplace: Car/motor vehicle	2.7	3.1	5.3	-1.9	-2.0	-2.1	-1.8	-2.1	-1.0	0.5	-1.3	-1.7	-2.3	-1.8	-1.5	-1.7	-1.9	-1.9	-2.1	-2.2	-0.9	-2.1	-1.9	-2.1	-2.0
Handedness (chirality/laterality): Left-handed	2.7	3.2	7.1	1.8	2.0	1.7	1.9	1.9	1.2	0.1	1.9	2.7	0.7	0.8	2.3	2.2	2.0	1.7	2.1	2.3	1.9	2.0	1.9	1.7	2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.8	11.2	2.8	2.6	2.6	2.8	2.6	1.8	0.3	2.1	3.4	0.8	2.1	2.7	1.1	2.7	2.7	2.7	2.9	2.8	2.7	2.6	2.3	2.6
Neuroticism score	2.6	5.4	20.6	-1.8	-2.1	-2.4	-2.3	-2.2	-3.0	-0.2	-2.9	-1.0	-2.7	-3.6	-4.5	-1.3	-2.0	-2.7	-2.1	-2.1	-1.0	-2.3	-2.0	-2.2	-2.1
Worry (Nagel 2018)	2.5	5.3	15.4	-1.8	-2.1	-2.3	-2.6	-2.2	-3.9	-0.1	-2.7	-1.2	-1.5	-3.1	-3.9	-1.9	-2.0	-2.5	-2.3	-2.4	-0.8	-2.3	-1.9	-2.6	-2.0
Reaction Time	2.5	4.8	10.9	2.2	2.3	2.5	2.8	2.2	1.6	-1.7	1.5	2.2	1.0	3.3	0.5	2.1	2.3	2.5	2.4	2.6	2.4	2.4	2.0	2.6	2.2
Systolic Blood Pressure	2.5	12.6	22.2	-4.1	-3.8	-3.7	-4.2	-3.7	-3.1	0.9	-3.0	-3.7	-2.8	-3.6	-2.2	-2.9	-3.8	-3.9	-4.2	-4.1	-3.6	-4.2	-3.8	-4.7	-3.8
Medication for hormone replacement therapy	2.5	2.8	6.0	-1.9	-1.9	-1.7	-1.9	-1.6	-0.7	0.1	-1.5	-2.5	-1.9	-1.4	-0.9	-1.8	-1.9	-1.7	-1.9	-2.0	-2.0	-1.9	-1.7	-1.7	-1.8
Severe depression (siblings)	2.5	2.8	7.0	-1.4	-1.2	-1.4	-2.1	-1.0	-2.4	-0.7	-2.5	-0.6	-2.6	-2.2	-2.5	-2.2	-1.2	-1.6	-1.6	-1.7	-0.3	-1.3	-1.0	-2.0	-1.2
Stomach or abdominal pain in last month	2.5	3.2	6.4	-1.7	-1.9	-2.2	-1.7	-2.0	-2.5	0.0	-2.0	-1.7	-0.0	-1.6	-2.3	-0.5	-1.9	-2.1	-1.9	-2.1	-1.4	-2.3	-2.0	-1.5	-2.0
Medication: Ventolin 100micrograms inhaler	2.5	3.2	6.8	-1.9	-1.6	-1.7	-2.5	-1.5	-0.9	-0.1	-1.1	-1.9	-2.3	-1.9	-2.6	-2.1	-1.6	-1.9	-1.8	-1.8	-2.1	-1.7	-1.3	-2.5	-1.5
Age at last live birth	2.5	3.7	9.6	2.1	1.9	1.7	2.4	1.9	-0.7	-0.3	1.4	3.1	2.7	1.9	2.1	1.0	1.9	2.0	2.0	2.6	1.8	2.2	1.7	1.8	1.8
Friendships satisfaction	2.5	3.1	10.5	-1.6	-1.7	-1.9	-1.8	-1.7	-3.2	-0.4	-2.5	-1.3	-0.3	-2.4	-2.4	-1.2	-1.6	-1.9	-1.4	-1.7	-1.7	-1.7	-1.6	-1.2	-1.6
Illnesses of father: High blood pressure	2.5	3.1	6.8	-1.8	-1.7	-1.9	-2.3	-1.6	-2.2	-0.0	-1.5	-1.2	-2.0	-2.6	-1.8	-1.2	-1.6	-2.0	-1.8	-1.9	-1.5	-1.9	-1.4	-2.4	-1.6
Illnesses of siblings: Diabetes	2.4	2.9	6.4	-2.2	-1.7	-2.0	-2.0	-1.8	-1.0	0.3	-2.0	-0.7	-2.3	-1.8	-2.5	-0.6	-1.7	-2.0	-1.6	-1.5	-2.0	-1.7	-1.8	-1.6	-1.7
Frequency of depressed mood in last 2 weeks	2.3	3.2	12.3	-1.7	-1.6	-1.8	-1.9	-1.7	-2.3	-0.4	-2.7	-0.4	-2.5	-2.0	-3.5	-0.9	-1.6	-1.7	-1.6	-1.5	-1.3	-1.6	-1.6	-1.6	-1.5
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	6.6	-1.9	-1.9	-2.0	-1.4	-1.8	-2.2	-0.5	-2.6	-1.0	-2.0	-1.6	-1.9	-0.3	-1.9	-1.9	-1.8	-1.6	-1.5	-2.0	-2.0	-1.6	-1.9
Vitamin and mineral supplements	2.2	3.0	7.0	1.9	1.7	1.5	2.0	1.5	2.7	0.2	2.6	1.6	1.2	1.4	1.9	2.0	1.6	1.6	1.9	1.7	1.5	1.6	1.5	2.1	1.7
High cholesterol (Self-reported)	2.2	3.9	11.4	2.1	2.0	2.0	2.1	1.9	2.4	0.2	3.4	1.0	2.8	1.6	2.8	0.9	2.0	1.8	2.0	1.9	2.0	1.7	2.0	1.7	2.0
Unable to work because of sickness or disability	2.2	2.9	5.6	1.5	1.8	1.8	1.9	1.8	2.0	0.4	1.6	2.4	0.3	2.0	-0.2	1.8	1.7	1.8	2.0	2.0	1.2	1.9	1.7	2.3	1.8
Schizophrenia vs Biploar Disorder	2.1	2.7	6.8	1.8	1.7	1.5	1.9	1.7	0.7	-1.9	1.7	1.4	1.8	0.7	1.0	2.6	1.7	1.4	1.9	1.9	1.4	1.7	1.5	2.0	1.7
Verbal and Numeric Reasoning (VNR)	2.0	4.8	10.5	2.3	2.2	2.2	2.9	2.0	0.2	-0.4	1.6	3.2	1.3	2.3	1.9	3.2	2.2	2.6	2.4	2.8	2.2	2.3	1.9	2.3	2.1
Diabetes (mother)	2.0	2.5	3.9	-1.8	-1.8	-1.7	-1.7	-1.8	-1.1	0.2	-1.0	-1.5	-1.4	-1.0	-1.9	-1.9	-1.7	-1.7	-1.7	-1.8	-2.0	-1.8	-1.7	-1.7	-1.7
Hand grip strength (right)	2.0	5.4	9.0	-2.3	-2.7	-3.0	-2.3	-2.8	-1.3	-0.1	-1.7	-1.9	-0.9	-2.7	-0.1	-2.4	-2.7	-2.9	-2.9	-2.9	-1.5	-2.8	-2.7	-2.9	-2.8
Number of children fathered	2.0	2.2	3.5	-1.5	-1.7	-1.6	-1.6	-1.8	-0.7	0.7	-1.2	-1.6	-1.5	-1.4	-1.0	-1.3	-1.8	-1.7	-1.9	-1.8	-0.9	-1.7	-1.8	-1.6	-1.9
Neuroticism (Nagel 2018)	1.9	4.5	19.1	-1.7	-1.9	-2.1	-2.2	-2.0	-2.9	0.0	-2.6	-1.3	-2.1	-2.8	-4.4	-1.1	-1.9	-2.3	-1.9	-2.0	-1.1	-2.2	-1.8	-2.0	-1.8
Sensitivity / hurt feelings	1.9	3.2	11.8	-1.6	-1.8	-1.9	-1.5	-1.8	-2.4	-0.2	-2.1	-0.7	-2.5	-2.1	-3.4	-0.2	-1.7	-2.0	-1.6	-1.4	-1.2	-1.8	-1.8	-1.5	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.9	4.2	9.4	-1.8	-2.1	-2.2	-2.6	-2.2	-1.7	0.0	-0.8	-2.3	0.1	-2.5	-1.4	-2.6	-2.1	-2.5	-2.5	-2.6	-1.0	-2.4	-1.9	-3.1	-2.2
Risk taking	1.9	2.8	5.1	-1.6	-1.9	-1.9	-2.1	-1.8	-0.4	-0.1	-1.6	-1.9	-1.9	-1.8	-1.0	-1.3	-1.8	-1.9	-1.8	-2.3	-1.9	-1.8	-1.7	-1.3	-1.8
Fractured/broken bones in last 5 years	1.9	2.5	4.3	1.7	1.9	2.0	1.4	2.1	1.6	0.0	1.1	0.6	0.4	1.8	0.9	1.3	1.9	2.0	2.0	1.7	0.8	1.9	2.0	1.7	2.0
Bipolar Disorder (2018)	1.8	2.8	15.3	-1.8	-1.4	-1.6	-1.6	-1.4	-1.0	0.2	-2.6	-0.2	-3.9	-1.7	-1.7	-2.0	-1.4	-1.6	-1.7	-1.4	-0.8	-1.3	-1.3	-1.9	-1.5
Blood Red Count	1.8	17.8	26.5	-4.8	-4.7	-4.6	-4.8	-4.8	-5.2	-0.6	-3.8	-3.1	-1.0	-4.5	-4.0	-2.8	-4.7	-5.0	-4.9	-4.5	-4.2	-4.7	-4.7	-4.9	-4.8
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	9.8	-1.3	-1.6	-1.7	-1.7	-1.8	-1.5	0.0	-2.0	-1.2	-1.8	-2.3	-3.1	-1.2	-1.6	-1.8	-1.5	-1.5	-1.4	-1.7	-1.6	-1.5	-1.6
Mouth/teeth dental problems	1.8	2.8	5.6	1.8	1.7	1.5	2.0	1.5	0.3	0.2	1.2	2.1	2.1	0.8	2.4	2.1	1.7	1.5	1.9	2.1	1.6	1.8	1.6	2.1	1.7
Neck or shoulder pain in last month	1.8	2.6	4.6	-1.8	-1.7	-2.0	-1.6	-1.8	-0.6	0.0	-2.1	-0.9	-2.0	-2.1	-1.9	-0.1	-1.7	-2.0	-1.4	-1.4	-1.8	-1.8	-1.6	-1.6	-1.6
Pain experienced in last month	1.8	3.0	4.5	1.7	1.9	1.8	2.0	1.9	0.4	0.4	1.5	2.1	2.1	1.7	1.9	1.1	1.9	2.0	1.8	2.0	1.6	2.1	1.7	1.9	1.8
Allergy or Eczema	1.7	4.5	11.5	-2.2	-2.0	-1.9	-2.9	-1.9	-2.3	-0.0	-1.9	-3.1	-1.3	-1.9	-1.7	-3.4	-2.0	-1.9	-2.2	-2.5	-2.3	-2.0	-1.6	-2.6	-1.8
Average weekly spirits intake	1.7	2.1	8.3	-1.3	-1.4	-1.6	-1.6	-1.3	-1.5	-0.1	-1.6	-1.8	0.4	-1.0	-1.2	-2.9	-1.4	-1.3	-1.5	-1.5	-0.9	-1.5	-1.2	-2.0	-1.4
Angina	1.7	2.2	5.9	1.9	1.5	1.4	1.5	1.5	1.7	0.6	1.7	1.5	2.4	0.5	1.6	0.6	1.6	1.2	1.7	1.3	1.6	1.4	1.7	1.8	1.6
Multivitamins +/- minerals	1.7	2.1	4.6	-1.6	-1.4	-1.1	-1.9	-1.2	-1.8	-0.2	-2.1	-1.8	-1.3	-1.0	-1.3	-2.0	-1.3	-1.1	-1.5	-1.5	-1.6	-1.3	-1.1	-1.9	-1.3
Happiness	1.7	2.0	6.9	-1.1	-1.1	-1.5	-1.4	-1.3	-2.6	-0.5	-1.8	-0.8	-1.1	-2.1	-2.5	-1.4	-1.1	-1.5	-1.2	-1.4	-0.7	-1.4	-1.1	-1.3	-1.1
Asthma	1.7	3.4	12.0	-2.0	-1.4	-1.3	-2.8	-1.0	-0.6	-0.7	-1.3	-2.1	-3.1	-0.9	-3.5	-2.7	-1.4	-1.2	-1.8	-2.1	-1.8	-1.3	-0.8	-2.6	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	4.0	-1.4	-1.4	-1.4	-1.7	-1.4	-1.2	0.2	-1.8	-1.5	-1.0	-2.0	-0.9	-1.7	-1.4	-1.8	-1.5	-1.5	-1.2	-1.6	-1.3	-1.6	-1.4
Qualifications: nursing, teaching	1.7	2.6	4.2	1.9	1.7	1.6	1.9	1.7	0.6	-0.2	1.4	1.8	2.0	1.8	1.3	2.0	1.7	1.8	1.6	1.7	1.8	1.7	1.6	1.7	1.7
Asthma (self-reported)	1.7	3.4	11.9	-2.0	-1.3	-1.3	-2.8	-1.0	-0.5	-0.7	-1.4	-2.1	-3.2	-0.9	-3.5	-2.6	-1.4	-1.1	-1.7	-2.0	-1.8	-1.3	-0.8	-2.6	-1.1
Intelligence (Savage-Jansen 2018)	1.6	4.8	16.6	2.0	2.0	2.1	3.0	1.9	-0.8	-0.6	0.8	3.7	1.1	1.9	1.3	4.1	2.0	2.4	2.4	2.9	1.8	2.3	1.7	2.9	1.9
Mean Putamen Volume	1.6	1.8	6.1	-1.1	-1.2	-1.2	-1.5	-0.9	-2.3	-0.4	-2.5	-1.4	-1.3	-1.1	-2.0	-1.9	-1.1	-1.0	-1.0	-1.1	-1.4	-1.0	-0.8	-1.5	-0.9
Triglycerides	1.6	2.6	5.7	-1.7	-1.7	-1.9	-1.9	-1.7	-1.2	0.2	-1.2	-1.5	-1.1	-1.9	-0.9	-0.8	-1.8	-1.9	-1.8	-1.7	-2.4	-1.8	-1.7	-1.8	-1.9
Respiratory disease	1.6	3.5	11.1	-2.3	-1.6	-1.5	-2.6	-1.2	-0.1	0.1	-1.3	-1.6	-3.3	-0.5	-3.3	-2.4	-1.6	-1.3	-1.8	-1.8	-2.2	-1.5	-1.2	-2.7	-1.4
Sitting height	1.6	11.3	17.8	-3.7	-3.9	-4.0	-4.1	-3.8	-2.4	0.3	-3.1	-3.4	-1.3	-3.3	-1.4	-2.4	-4.0	-3.8	-4.0	-3.7	-3.9	-3.7	-3.8	-4.2	-3.9
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	4.6	-1.8	-1.7	-1.6	-1.9	-1.5	-0.5	-0.7	-1.5	-1.6	-2.1	-1.2	-2.1	-0.8	-1.7	-1.6	-1.8	-2.0	-1.7	-1.6	-1.6	-1.5	-1.7
Cholesterol lowering medication	1.6	2.3	6.8	1.3	1.5	1.6	1.8	1.4	2.6	-0.2	2.1	1.8	-0.3	1.5	0.7	0.4	1.5	1.7	1.8	2.0	1.0	1.6	1.5	1.6	1.6
Neuroticism	1.5	3.7	18.9	-1.2	-1.6	-1.9	-1.9	-1.7	-2.3	-1.2	-2.2	-0.5	-2.4	-3.0	-4.3	0.0	-1.6	-2.2	-1.7	-1.7	-0.6	-2.0	-1.6	-1.8	-1.6
Medication: Simvastatin	1.5	2.2	6.9	1.2	1.4	1.5	1.4	1.5	2.6	0.1	2.4	0.9	1.4	1.8	1.7	1.3	1.4	1.6	1.4	1.3	0.9	1.3	1.5	1.3	1.5
Illnesses of mother	1.5	1.8	3.7	1.7	1.3	1.4	1.6	1.3	1.1	0.1	0.4	1.4	1.5	1.6	1.5	1.1	1.3	1.4	1.5	1.8	1.2	1.7	1.2	1.9	1.3
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.2	-1.4	-1.7	-1.6	-1.2	-1.7	-0.6	-0.0	-0.3	-1.2	-0.6	-0.7	-1.8	-0.2	-1.7	-1.6	-1.7	-1.5	-1.0	-1.7	-1.8	-1.5	-1.8
Chest pain or discomfort	1.5	2.2	5.5	-1.1	-1.3	-1.5	-1.8	-1.2	-1.0	-0.2	-1.0	-2.3	-0.2	-1.6	-1.9	-2.3	-1.3	-1.6	-1.6	-2.1	-0.8	-1.6	-1.1	-1.8	-1.3
Neuroticism (2016)	1.4	1.9	7.6	-0.8	-1.4	-1.4	-1.2	-1.5	-2.2	-0.9	-1.6	-0.6	-0.2	-2.4	-2.8	0.1	-1.3	-1.9	-1.0	-0.9	-1.0	-1.5	-1.3	-1.1	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	7.3	-1.5	-1.9	-2.0	-2.3	-1.9	-1.8	0.1	-1.0	-1.6	0.7	-2.5	-1.0	-2.4	-1.9	-2.4	-2.2	-2.0	-0.8	-2.1	-1.7	-2.7	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.2	8.5	-1.4	-1.4	-1.2	-1.8	-1.4	-0.9	-0.1	-1.4	-1.1	-1.9	-1.6	-2.9	-1.9	-1.4	-1.4	-1.6	-1.7	-0.8	-1.4	-1.2	-1.5	-1.4
Pulse rate, automated reading	1.4	4.4	11.6	-1.8	-2.4	-2.6	-2.3	-2.5	-2.5	0.6	-0.2	-1.6	1.6	-3.4	-1.7	-0.9	-2.4	-3.0	-2.1	-1.8	-2.0	-2.3	-2.6	-1.7	-2.4
Loneliness, isolation	1.4	1.9	6.4	-1.0	-1.0	-1.2	-1.9	-0.8	-1.2	-0.3	-1.4	-1.5	-1.4	-2.3	-2.5	-1.8	-0.9	-1.4	-1.2	-1.8	-0.8	-1.3	-0.5	-1.6	-0.8
Number of self-reported non-cancer illnesses	1.4	2.4	5.2	-1.6	-1.2	-1.3	-2.2	-1.1	-1.3	0.2	-1.6	-1.0	-2.1	-2.0	-2.3	-2.1	-1.2	-1.6	-1.5	-1.6	-1.1	-1.4	-0.9	-2.3	-1.2
Pain type(s) experienced in last month: Hip pain	1.4	1.8	6.2	-1.3	-1.2	-1.1	-1.7	-1.0	-0.3	0.2	-1.2	-2.5	-1.7	-1.4	-1.3	-1.4	-1.2	-1.3	-1.4	-2.0	-1.0	-1.4	-0.9	-1.5	-1.1
Prostate Cancer	1.3	1.8	3.5	-1.5	-1.4	-1.3	-1.7	-1.4	-1.1	0.2	-1.9	-1.6	-1.2	-1.3	-1.5	-0.4	-1.5	-1.3	-1.4	-1.6	-1.6	-1.4	-1.3	-1.0	-1.3
Number of full brothers	1.3	1.7	4.3	1.2	1.5	1.5	1.1	1.6	2.1	-0.1	0.6	1.2	-0.7	1.3	-0.4	1.1	1.5	1.5	1.6	1.2	0.9	1.5	1.7	1.4	1.7
Knee pain experienced in last month	1.3	2.0	4.9	-1.3	-1.3	-1.3	-1.8	-1.2	0.1	-0.4	-1.2	-2.2	-2.2	-1.3	-1.7	-1.4	-1.3	-1.4	-1.6	-2.0	-1.0	-1.5	-1.1	-1.5	-1.3
Diastolic blood pressure, automated reading	1.3	3.9	7.6	-1.8	-1.7	-1.7	-2.6	-1.7	-1.0	-0.0	-0.8	-2.5	-2.3	-2.5	-2.3	-2.6	-1.8	-2.2	-2.2	-2.4	-1.3	-2.3	-1.6	-2.8	-1.8
Fasting Glucose	1.2	1.4	3.1	1.8	1.4	1.2	1.2	1.2	0.6	-1.0	0.9	0.9	1.3	1.4	0.7	1.4	1.4	0.8	1.2	1.3	1.1	1.2	1.1	1.5	1.1
Maternal smoking around birth	1.2	1.7	12.0	0.9	0.9	1.0	1.3	0.9	3.5	-0.1	1.2	2.1	-1.6	1.1	0.9	1.6	1.0	0.8	0.9	1.3	1.1	1.1	0.9	0.6	0.9
Pulse wave reflection index	1.2	1.5	5.8	1.2	1.4	1.4	0.9	1.4	2.4	-0.0	1.0	0.8	-1.9	1.2	-0.1	-0.1	1.4	1.4	1.1	0.7	1.2	1.2	1.7	0.8	1.5
Age at first live birth	1.2	2.1	10.1	1.4	1.1	0.9	1.7	1.0	-1.6	-0.0	-0.1	3.2	2.5	0.9	1.8	1.0	1.2	1.1	1.2	2.0	1.5	1.6	1.0	0.8	1.0
Medication for pain relief, constipation, heartburn	1.2	2.0	4.1	-1.6	-1.8	-1.8	-1.2	-1.7	-1.8	0.1	-1.7	-1.3	-0.2	-1.5	-0.1	-0.4	-1.7	-1.6	-1.4	-1.4	-2.0	-1.6	-1.9	-0.8	-1.7
Medication: Atorvastatin	1.2	1.5	4.0	1.1	1.4	1.3	1.3	1.3	1.9	0.4	1.3	2.0	-0.2	0.8	1.0	0.8	1.4	1.1	1.3	1.5	1.3	1.4	1.4	0.9	1.4
Average weekly beer plus cider intake	1.2	1.7	9.2	-1.1	-1.1	-1.3	-1.1	-1.1	0.4	0.3	-1.5	-0.4	-3.0	-1.8	-2.1	-1.5	-1.1	-1.6	-1.0	-1.0	-0.7	-1.1	-1.2	-0.9	-1.1
Type 2 Diabetes (T2D) (2018)	1.1	2.1	5.3	-1.4	-1.6	-1.9	-1.4	-1.6	-0.3	-0.3	-1.3	-0.0	-2.3	-2.1	-1.9	-0.4	-1.5	-2.1	-1.6	-1.3	-0.7	-1.6	-1.5	-1.6	-1.6
Serious illness, injury or assault to yourself	1.1	1.4	2.7	1.5	1.5	1.5	0.8	1.5	1.2	-0.3	1.4	0.7	1.5	0.7	0.7	0.3	1.4	1.3	1.3	1.1	1.0	1.3	1.7	0.9	1.5
Financial difficulties in last 2 years	1.1	1.5	3.0	-1.4	-1.3	-1.3	-1.1	-1.6	-0.9	0.2	-0.9	-1.5	-0.6	-1.3	-1.7	0.1	-1.4	-1.4	-1.1	-1.1	-1.6	-1.4	-1.5	-0.7	-1.4
Number of full sisters	1.1	1.3	8.9	-1.2	-1.0	-0.9	-1.0	-1.1	0.0	0.2	-0.6	-0.9	-3.0	-1.1	-2.0	-0.3	-1.0	-1.1	-0.9	-1.3	-1.2	-1.2	-1.1	-0.3	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.5	-0.8	-1.1	-1.1	-1.4	-1.2	-1.2	0.2	-1.3	-1.5	-0.6	-1.1	-1.5	-1.0	-1.1	-1.0	-1.2	-1.6	-0.9	-1.3	-0.9	-1.3	-1.1
Ever had prostate specific antigen (PSA) test	1.1	1.3	3.6	-1.2	-1.2	-1.2	-1.4	-1.1	-1.5	-0.6	-1.7	-0.5	0.0	-0.7	-1.2	-1.0	-1.2	-1.0	-1.5	-1.3	-0.3	-1.2	-1.0	-1.9	-1.2
Bipolar Disorder or Schizophrenia	1.0	2.5	13.7	-1.5	-1.2	-1.3	-1.4	-1.2	-1.2	-1.6	-2.6	0.1	-3.7	-1.7	-2.3	-1.3	-1.2	-1.4	-1.4	-1.2	-0.7	-1.2	-1.1	-1.5	-1.2
Lung FEV1/FVC ratio	1.0	4.9	20.0	-2.2	-1.8	-1.7	-1.8	-1.9	-2.6	-2.6	-3.9	0.3	-4.5	-3.0	-3.3	-1.4	-1.8	-2.1	-1.5	-0.9	-1.8	-1.4	-1.8	-1.4	-1.8
Chronic bronchitis/emphysema (father)	1.0	1.2	5.7	-1.3	-1.0	-1.1	-1.0	-1.0	-0.3	0.3	-0.6	-0.5	-2.4	-1.1	-2.1	-1.1	-1.0	-1.1	-0.8	-0.7	-1.2	-1.0	-1.0	-1.0	-0.9
Medication: Paracetamol	1.0	1.6	3.4	1.4	1.5	1.5	1.4	1.3	1.5	0.4	0.5	1.5	0.6	1.4	0.7	0.8	1.5	1.3	1.3	1.6	1.8	1.6	1.5	1.0	1.4
Alcohol intake frequency.	1.0	2.4	6.1	-1.4	-1.7	-1.8	-2.0	-1.8	-0.3	0.1	-0.9	-1.1	-1.7	-2.5	-1.2	-0.4	-1.7	-2.2	-1.8	-1.6	-1.3	-1.8	-1.5	-2.1	-1.7
Ulcerative Colitis (UC)	0.9	1.6	4.0	0.9	1.2	1.4	1.6	1.2	0.3	0.3	1.6	1.9	0.1	0.8	1.4	2.0	1.2	1.3	1.4	1.6	1.0	1.5	1.1	1.7	1.2
Major Depression (MDD)	0.9	1.0	2.3	-1.0	-1.2	-1.2	-1.2	0.0	-0.6	0.0	-0.7	-1.5	-0.8	-1.4	-1.1	-0.7	-1.1	-1.2	-0.9	-1.4	-1.1	-1.4	-1.2	-0.6	-1.1
Blood Platelet Count	0.9	9.9	26.3	2.9	2.9	3.0	3.6	3.0	5.1	2.6	4.5	1.7	2.2	3.9	4.4	1.9	2.9	3.2	3.2	2.9	2.4	2.9	3.0	3.3	3.0
Heel T-Score	0.9	7.3	14.8	-2.6	-3.4	-3.5	-2.8	-3.4	-1.0	-1.0	0.2	-2.2	1.3	-3.5	-1.9	-2.2	-3.2	-3.9	-2.9	-2.6	-2.5	-3.4	-3.4	-2.6	-3.3
Qualifications: A levels/AS levels or equivalent	0.9	2.1	5.5	1.2	1.3	1.3	1.7	1.1	-1.6	-0.8	0.8	2.1	2.0	2.1	0.8	2.3	1.2	1.5	1.3	1.7	1.3	1.4	1.0	1.3	1.2
Migraine (self-reported)	0.9	1.2	2.7	-1.0	-1.2	-1.2	-1.0	-1.2	-1.1	0.1	-1.4	-0.3	-1.6	-1.5	-1.3	-0.5	-1.1	-1.4	-1.0	-0.9	-0.6	-1.1	-1.2	-0.9	-1.1
Supplements: Vitamin C	0.9	1.0	2.1	-1.1	-1.1	-1.2	-1.0	-1.1	-1.5	-0.5	-1.2	-0.9	-0.3	-1.1	-0.7	-0.5	-1.1	-1.1	-1.1	-1.1	-1.1	-1.0	-1.2	-0.8	-1.1
Mood swings	0.9	1.7	10.7	-0.9	-1.1	-1.2	-1.3	-1.2	-0.8	0.1	-1.0	-1.2	-1.6	-2.2	-3.3	0.1	-1.0	-1.4	-1.1	-1.3	-0.4	-1.3	-1.0	-1.0	-1.1
Rheumatoid Arthritis	0.8	1.1	2.4	1.2	1.1	1.0	1.3	1.0	0.7	-0.2	0.5	1.6	1.5	0.7	0.8	1.0	1.0	0.9	1.1	1.2	1.4	1.2	1.1	1.1	0.9
Fed-up feelings	0.8	1.5	4.6	-0.7	-1.2	-1.4	-1.2	-1.3	-0.8	-0.1	-1.1	-1.0	-0.4	-2.1	-2.1	-0.6	-1.2	-1.7	-1.1	-1.3	-0.6	-1.5	-1.3	-1.0	-1.3
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	4.4	-0.6	-0.7	-1.1	-1.1	-0.7	-1.1	-0.1	-1.3	-0.5	-0.0	-2.1	-0.9	-1.6	-0.6	-1.1	-0.8	-0.7	-0.4	-0.8	-0.7	-1.3	-0.7
Arm fat percentage (right)	0.8	3.2	16.6	2.0	1.9	1.8	1.5	1.8	4.1	-0.4	2.9	0.7	1.1	1.3	-0.7	0.4	1.9	1.5	1.7	1.3	2.2	1.8	2.1	1.5	1.8
Hip circumference	0.8	3.3	21.1	2.0	1.9	1.7	1.6	1.8	4.6	0.0	2.7	0.7	0.3	1.5	-0.2	0.8	1.9	1.5	1.7	1.2	2.0	1.8	2.1	1.5	1.9
Worrier / anxious feelings	0.8	1.4	7.6	-0.3	-0.8	-1.2	-1.2	-1.0	-2.8	0.1	-1.0	-0.7	0.4	-2.2	-2.1	-0.7	-0.7	-1.4	-1.1	-1.2	0.7	-1.1	-0.7	-1.2	-0.9
Pulse wave Arterial Stiffness index	0.8	0.9	3.1	-0.8	-0.8	-0.9	-1.3	-0.9	-0.3	0.6	-0.8	-0.9	-1.8	-1.3	-1.0	-0.8	-0.9	-1.1	-1.0	-1.2	-1.0	-0.9	-0.7	-1.1	-0.8
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	3.1	1.7	1.5	1.4	1.1	1.6	1.0	-0.2	1.2	0.4	0.9	1.2	0.6	0.5	1.6	1.4	1.4	0.9	1.6	1.2	1.8	1.2	1.6
Birth weight	0.8	1.6	3.5	1.2	1.3	1.5	1.4	1.4	1.7	0.1	1.3	1.0	-0.1	1.9	1.3	1.1	1.2	1.7	1.4	1.6	0.6	1.4	1.4	1.1	1.4
High blood pressure (siblings)	0.8	1.2	4.8	-1.3	-0.9	-0.9	-1.5	-0.7	-0.9	-0.1	-0.3	-0.6	-1.8	-1.2	-2.2	-0.9	-0.8	-0.8	-1.1	-1.2	-1.0	-1.1	-0.6	-1.6	-0.8
Arm fat percentage (left)	0.8	3.3	17.6	2.0	1.9	1.8	1.5	1.8	4.2	-0.3	3.0	0.7	1.2	1.2	-0.7	0.4	1.9	1.5	1.7	1.4	2.1	1.8	2.1	1.5	1.8
Medication for cholesterol	0.8	1.3	4.4	1.5	1.1	0.9	1.3	1.1	0.2	-0.1	0.6	1.1	1.4	0.8	0.5	2.1	1.2	1.1	1.2	1.0	1.5	1.2	0.9	1.5	1.1
Miserableness	0.8	1.4	12.3	-0.4	-0.6	-0.7	-0.9	-0.6	-0.2	-0.3	-1.3	-0.5	-2.5	-2.0	-3.5	-0.4	-0.6	-1.1	-0.5	-0.6	-0.2	-0.9	-0.5	-0.6	-0.6
Depressed Affect (Nagel 2018)	0.7	1.4	7.2	-0.9	-1.0	-1.0	-1.3	-0.9	-0.5	0.1	-1.5	-1.0	-1.8	-2.2	-2.7	-0.5	-0.9	-1.4	-0.9	-1.2	-0.5	-1.2	-0.8	-1.0	-0.8
Ovarian Cancer	0.7	0.9	2.3	1.1	1.1	1.0	0.9	1.1	0.7	0.4	1.2	0.2	1.5	1.3	1.3	0.1	1.1	1.1	0.9	0.7	0.9	0.9	1.1	1.0	1.0
HDL Cholesterol	0.7	1.2	5.0	0.9	1.0	1.3	1.3	1.1	-0.2	-0.0	1.1	0.4	2.2	1.3	2.0	0.4	1.0	1.1	1.0	0.7	1.4	0.9	0.9	1.1	1.1
Blood White Count	0.7	4.9	10.1	-2.4	-2.6	-2.2	-2.7	-2.8	0.2	0.4	-0.8	-3.2	-0.9	-1.8	-1.6	-1.7	-2.6	-2.8	-2.6	-2.8	-2.5	-2.6	-2.6	-1.9	-2.6
Smoking Status	0.7	1.7	10.4	0.5	1.1	1.5	0.9	1.2	3.2	1.7	0.8	-0.3	-2.2	1.6	0.5	-0.1	1.1	1.2	1.1	0.9	0.1	1.2	1.2	1.2	1.1
Supplements: Glucosamine	0.7	0.9	5.6	-0.6	-0.7	-0.9	-1.1	-0.6	-1.3	-0.1	-0.9	-1.1	0.0	-1.4	0.0	-2.4	-0.7	-1.0	-0.9	-1.0	-0.8	-0.9	-0.5	-1.2	-0.7
Qualifications: None of the above	0.7	1.4	7.8	-1.3	-0.9	-0.8	-1.2	-1.0	1.4	1.1	-0.6	-1.1	-2.8	-0.9	-1.1	-2.1	-1.0	-1.0	-0.8	-1.0	-1.4	-0.9	-0.8	-1.0	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.7	1.0	1.0	1.0	0.8	1.0	1.5	0.2	0.9	-0.5	-0.6	0.7	1.7	-0.2	0.9	0.9	0.7	0.1	1.0	0.8	1.0	1.1	0.9
Arm fat mass (right)	0.7	2.8	21.5	1.9	1.7	1.5	1.0	1.6	4.6	-0.1	2.8	0.5	0.2	0.9	-0.7	-0.1	1.7	1.1	1.3	0.9	2.1	1.5	1.9	1.0	1.6
Exposure to tobacco smoke outside home	0.7	0.9	4.9	1.0	1.1	0.9	0.9	1.0	2.2	0.2	1.0	0.6	-1.1	0.5	-0.4	0.5	1.0	0.8	0.8	0.5	1.2	0.8	1.1	0.6	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	3.4	-0.8	-0.8	-0.9	-1.1	-0.7	-0.1	-0.8	-0.1	-1.2	-0.1	-1.2	-1.8	-1.8	-0.7	-1.2	-0.9	-1.2	-0.6	-0.9	-0.6	-0.8	-0.8
Arm fat mass (left)	0.7	3.0	22.6	1.9	1.7	1.5	1.1	1.6	4.8	-0.1	2.9	0.6	0.1	0.9	-0.8	0.1	1.7	1.2	1.4	1.0	2.1	1.6	2.0	1.0	1.7
Ever taken oral contraceptive pill	0.7	0.8	5.2	-0.9	-0.8	-0.7	-1.0	-0.6	0.2	-0.1	-0.2	-2.3	-1.2	-0.4	-0.6	-0.3	-0.8	-0.6	-0.8	-1.3	-1.2	-1.1	-0.8	-0.7	-0.8
Coronary Artery Disease (CAD)	0.6	0.7	3.3	0.3	0.7	0.3	0.5	0.9	1.6	0.0	1.8	-0.6	0.8	0.2	1.1	-0.9	0.8	0.8	0.8	0.1	0.5	0.5	0.8	0.8	0.9
HbA1C	0.6	0.6	2.6	0.9	0.6	0.7	0.7	0.3	0.2	-0.3	0.7	1.6	-0.0	0.3	1.6	0.6	0.5	0.5	0.7	1.1	1.1	1.2	0.9	0.2	0.8
Hand grip strength (left)	0.6	1.6	2.9	-1.3	-1.5	-1.7	-1.1	-1.6	-0.4	-0.1	-0.5	-0.8	0.3	-1.7	0.6	-0.5	-1.5	-1.7	-1.6	-1.4	-0.9	-1.6	-1.7	-1.6	-1.6
Ever had hysterectomy (womb removed)	0.6	0.7	3.9	-0.9	-0.7	-0.5	-0.7	-0.5	0.3	-0.4	-1.0	-1.2	-2.0	-0.8	-1.6	-0.9	-0.7	-0.7	-0.6	-0.8	-1.0	-0.5	-0.6	-0.1	-0.6
Medication: Co-codamol	0.6	0.7	3.3	0.8	0.9	1.0	0.9	1.0	1.8	0.0	0.8	-0.3	-0.6	0.4	-0.3	-0.7	0.9	1.0	1.0	0.6	0.8	0.8	1.0	1.2	1.0
Hair/balding pattern: Pattern 2	0.6	0.8	7.6	-0.6	-0.4	-0.3	-0.8	-0.2	-0.1	0.1	-0.7	-0.7	-2.8	-0.1	-2.4	-0.8	-0.3	-0.3	-0.3	-0.6	-0.7	-0.3	-0.2	-0.4	-0.3
Breastfed as a baby	0.6	0.8	3.9	0.6	0.7	0.9	0.9	0.8	1.2	0.5	0.3	0.9	0.3	1.5	2.0	-0.7	0.7	0.9	0.8	0.9	0.2	1.1	0.8	0.8	0.7
Shortness of breath walking on level ground	0.6	0.7	2.4	-0.8	-0.6	-0.6	-1.2	-0.4	0.2	0.2	-0.6	-1.6	-1.1	-0.8	-1.4	-1.3	-0.6	-0.6	-0.6	-1.0	-1.2	-0.7	-0.5	-0.6	-0.5
Comparative height size at age 10	0.6	3.6	8.6	-1.6	-1.9	-2.2	-2.3	-2.0	-2.9	0.3	-2.0	-1.5	-0.4	-1.9	-0.6	-2.6	-2.0	-2.0	-2.2	-2.0	-1.8	-1.8	-1.9	-2.3	-2.0
Medication: Aspirin	0.6	0.8	3.2	0.9	1.0	0.9	0.7	1.1	1.3	0.2	1.8	0.7	0.5	0.9	1.1	-0.1	1.1	1.0	0.8	0.5	0.9	0.9	1.2	0.6	1.0
Leg fat-free mass (right)	0.6	3.1	22.9	2.0	1.8	1.4	1.1	1.8	4.8	0.2	2.7	0.9	-1.0	1.2	0.4	-0.1	1.7	1.4	1.3	1.0	2.2	1.7	2.1	0.7	1.8
Average weekly red wine intake	0.6	1.0	3.3	0.9	0.9	1.1	1.1	1.0	0.3	-0.4	0.9	0.7	1.8	1.4	1.5	0.4	0.9	1.1	0.8	1.0	0.9	1.0	1.0	0.5	0.9
Mineral and other dietary supplements	0.6	0.8	1.5	0.5	0.8	0.9	0.8	0.8	1.1	-0.0	0.9	1.2	-0.6	1.2	-0.2	1.2	0.8	1.1	1.0	1.2	0.5	0.9	0.8	0.8	0.9
Illnesses of father: None of the above (group 1)	0.6	0.8	2.3	1.0	0.8	0.7	1.3	0.8	0.5	0.1	-0.2	1.1	0.7	0.7	0.7	1.0	0.8	0.9	1.1	1.1	0.9	0.9	0.7	1.5	0.8
Leg predicted mass (right)	0.6	3.4	24.1	2.1	1.9	1.6	1.2	1.9	4.9	0.2	2.9	1.0	-0.9	1.3	0.5	-0.1	1.9	1.5	1.4	1.1	2.3	1.9	2.2	0.8	1.9
Medication: Paracetamol	0.6	1.0	2.0	1.1	1.1	1.2	1.0	1.0	1.4	0.4	0.4	0.8	0.5	1.4	0.2	0.8	1.1	1.2	1.0	1.1	1.3	1.1	1.1	0.7	1.1
Number of operations (self-reported)	0.6	0.9	9.3	-0.5	-0.1	0.1	-0.9	-0.1	0.6	0.3	-1.1	-1.0	-3.1	-0.5	-1.7	-1.6	-0.2	-0.3	-0.2	-0.6	-0.4	-0.2	0.1	-0.4	-0.1
Heart attack/myocardial infarction (self-reported)	0.6	0.8	2.4	1.2	1.0	0.7	0.9	0.9	1.6	0.6	1.4	0.2	1.1	0.2	1.4	0.4	1.0	0.5	0.7	0.5	1.3	0.5	0.8	0.7	0.8
Age at First Birth	0.5	0.7	7.4	-0.2	-0.3	-0.5	-0.1	-0.3	-2.7	-0.7	-1.5	1.1	1.7	-0.0	0.8	0.4	-0.2	-0.5	-0.4	-0.0	-0.1	-0.2	-0.5	-0.4	-0.5
Crohns Disease (2012)	0.5	0.8	2.6	0.8	0.7	0.8	1.4	0.8	0.3	0.0	0.8	1.5	-0.2	1.2	1.2	1.6	0.8	0.8	0.5	0.8	1.4	0.7	0.4	0.9	0.4
Number of treatments/medications taken	0.5	0.9	3.7	-0.7	-0.5	-0.6	-1.3	-0.5	0.4	0.2	-0.3	-1.0	-1.2	-0.7	-1.9	-1.8	-0.5	-0.8	-0.9	-1.1	-0.3	-0.8	-0.2	-1.6	-0.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	3.5	0.4	0.4	0.4	0.6	0.2	0.3	0.6	0.3	1.8	0.1	0.7	-0.7	1.9	0.4	0.4	0.4	0.8	0.7	0.8	0.3	0.7	0.3
Trunk fat percentage	0.5	1.8	8.0	-1.0	-1.3	-1.4	-1.6	-1.3	0.4	-0.3	-0.1	-2.0	0.5	-1.7	-2.8	-1.1	-1.3	-1.6	-1.4	-1.6	-0.9	-1.4	-1.1	-1.5	-1.3
Medication: Atenolol	0.5	0.6	6.2	-0.5	-0.3	-0.4	-1.1	-0.2	0.0	0.1	-0.5	-1.0	-0.9	-0.6	-0.2	-2.5	-0.2	-0.5	-0.5	-0.9	-0.2	-0.5	0.1	-1.0	-0.2
Alcohol usually taken with meals	0.5	0.8	5.0	-0.7	-0.7	-0.9	-1.0	-0.6	-2.2	-0.4	-1.2	-0.5	-0.3	-1.2	-0.6	-1.4	-0.7	-0.8	-0.9	-0.8	-0.3	-0.7	-0.7	-1.2	-0.7
Had other major operations	0.5	0.6	5.4	0.0	0.3	0.4	-0.4	0.6	0.5	-0.5	-0.1	-0.7	-2.3	-0.5	-1.7	-1.7	0.3	0.2	0.1	-0.3	0.0	0.2	0.5	0.1	0.4
Heart attack	0.5	0.7	2.3	1.1	0.9	0.6	0.8	0.8	1.5	0.5	1.3	0.2	0.9	0.0	1.4	0.3	0.9	0.3	0.6	0.4	1.3	0.4	0.7	0.6	0.7
Pain all over the body in last month	0.5	0.5	2.9	0.6	0.6	0.6	0.7	0.4	1.7	-0.1	0.4	1.5	-0.2	0.5	-0.0	1.1	0.5	0.5	0.8	1.0	0.2	0.6	0.5	1.0	0.5
Medication: Ramipril	0.5	0.7	2.5	0.7	0.9	0.8	0.7	0.9	1.6	0.3	1.2	1.0	0.0	1.1	0.3	0.3	0.9	0.8	0.6	0.6	1.1	0.7	0.9	0.2	0.8
Pulse rate	0.5	0.9	2.8	-0.7	-1.0	-1.2	-0.8	-1.1	-1.6	0.7	-0.4	0.2	1.3	-1.7	-0.1	0.7	-1.0	-1.3	-0.7	-0.4	-0.8	-0.8	-1.2	-0.3	-1.0
Medication: Cholesterol lowering	0.5	0.8	3.4	0.8	0.7	0.6	0.6	0.7	1.9	0.7	1.7	0.1	1.4	0.3	1.4	0.8	0.8	0.4	0.5	0.1	1.0	0.5	0.8	0.5	0.6
Medication: Amlodipine	0.5	0.7	3.1	0.1	0.7	0.7	0.5	0.9	1.6	0.1	1.8	-0.3	0.6	1.2	0.9	-0.3	0.8	1.0	0.8	0.5	0.2	0.6	0.9	0.5	0.9
Chronic bronchitis/emphysema (mother)	0.5	0.6	5.6	-0.7	-0.3	-0.3	-1.0	-0.2	0.9	-0.5	-0.6	-1.1	-2.4	-0.6	-1.1	-0.4	-0.4	-0.4	-0.6	-0.8	-0.6	-0.6	-0.3	-0.9	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	6.4	-0.3	-0.4	-0.4	-0.7	-0.3	-0.8	-0.6	-0.9	-0.3	-0.9	-0.9	-2.5	-1.3	-0.4	-0.5	-0.4	-0.6	-0.1	-0.4	-0.3	-0.4	-0.4
Suffer from ‘nerves’	0.5	0.7	2.7	1.1	1.0	1.0	0.3	0.9	-0.5	-0.2	0.3	0.8	0.4	0.5	-1.2	-1.0	1.0	0.8	0.7	0.7	1.6	0.9	1.2	0.2	1.0
Eye problems/disorders: Cataract	0.5	0.5	2.4	0.8	0.7	0.9	0.7	0.7	0.0	0.1	-0.4	1.5	-0.2	0.3	0.1	1.4	0.7	0.5	0.7	1.2	0.4	0.8	0.6	0.6	0.7
Medication: Gliclazide	0.5	0.6	2.9	-1.0	-0.7	-0.6	-0.6	-0.7	-0.6	-0.3	-0.3	-0.4	-1.1	-1.2	-1.7	-0.6	-0.7	-0.9	-0.6	-0.7	-0.5	-0.7	-0.8	-0.2	-0.8
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.4	-0.5	-0.7	-0.7	-0.7	-0.8	-0.7	-0.1	-0.1	-1.2	1.6	-1.1	0.9	-1.0	-0.7	-0.9	-0.9	-1.2	-0.5	-0.9	-0.7	-0.8	-0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	4.8	-1.0	-0.6	-0.7	-0.4	-0.6	0.5	0.2	-0.6	0.7	-2.2	-0.8	-0.4	-0.2	-0.7	-0.8	-0.6	-0.0	-0.2	-0.3	-0.8	-0.9	-0.7
Irritable Bowel Disease (IBD)	0.4	0.9	3.5	0.5	0.5	0.7	1.4	0.5	0.1	-0.1	1.6	1.7	-1.2	0.2	0.5	1.9	0.6	0.6	0.8	1.1	0.9	1.0	0.4	1.5	0.4
Hearing difficulty/problems: Yes	0.4	0.6	1.3	0.5	0.8	0.9	0.8	0.7	1.1	0.5	0.8	1.0	0.2	0.7	-0.2	0.6	0.7	1.0	0.8	1.0	0.6	0.9	0.8	0.6	0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	3.4	0.7	0.6	0.4	0.6	0.7	0.0	0.1	-0.3	1.5	0.5	0.6	0.3	1.8	0.7	0.7	0.5	0.5	1.0	0.5	0.7	0.2	0.6
Ever used hormone-replacement therapy (HRT)	0.4	0.5	4.6	-0.7	-0.3	-0.0	-0.4	-0.1	1.4	0.5	-0.3	-0.7	-2.1	0.3	0.3	-1.3	-0.3	0.0	-0.2	-0.2	-1.3	-0.1	-0.1	-0.3	-0.1
Supplements: Zinc	0.4	0.5	0.9	0.4	0.8	0.8	0.5	1.0	0.4	-0.1	0.9	0.6	0.6	0.9	0.8	-0.8	0.8	0.8	0.6	0.5	0.9	0.7	0.9	0.3	0.7
Diabetes (father)	0.4	0.5	2.5	-0.6	-0.6	-0.6	-0.6	-0.5	-0.2	0.1	-0.9	0.7	-1.6	-0.6	-1.5	0.9	-0.5	-0.7	-0.3	-0.1	-1.0	-0.4	-0.5	-0.2	-0.5
Leg fat-free mass (left)	0.4	2.2	20.4	1.6	1.4	1.0	0.7	1.3	4.5	0.2	2.4	0.5	-1.3	0.9	-0.2	-0.5	1.3	1.0	0.8	0.6	1.8	1.3	1.7	0.4	1.3
Current tobacco smoking	0.4	0.7	4.0	0.6	0.8	1.1	0.7	0.8	2.0	0.5	0.6	-0.2	-0.5	1.5	-0.0	0.4	0.8	1.0	0.9	0.8	0.3	0.9	0.8	1.0	0.9
Leg predicted mass (left)	0.4	2.1	20.1	1.5	1.3	1.0	0.6	1.3	4.5	0.2	2.4	0.4	-1.4	0.9	-0.2	-0.6	1.2	0.9	0.8	0.5	1.8	1.3	1.6	0.3	1.3
Trunk fat mass	0.4	1.7	8.0	-0.8	-1.0	-1.2	-1.6	-1.1	1.4	-0.2	0.2	-1.8	-0.5	-1.6	-2.8	-1.4	-1.0	-1.5	-1.3	-1.5	-0.6	-1.1	-0.7	-1.6	-1.1
Past tobacco smoking	0.4	0.8	8.5	0.9	0.1	-0.2	0.4	0.0	-1.7	-0.0	0.7	0.4	2.9	-0.7	0.9	0.8	0.2	-0.2	0.1	0.1	1.4	-0.1	0.0	0.3	0.1
Illnesses of siblings	0.4	0.6	4.1	0.8	0.5	0.6	1.2	0.4	0.9	0.3	0.1	0.7	0.0	0.7	2.0	0.1	0.5	0.6	0.8	1.1	0.3	1.0	0.4	1.2	0.5
Number of live births	0.4	0.5	6.1	-0.0	0.1	0.2	0.1	0.2	1.9	-0.2	0.6	0.4	-2.5	-0.2	-1.0	-0.5	0.1	0.2	0.1	0.2	-0.1	0.1	0.1	-0.2	0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	5.8	-1.0	-1.0	-1.3	-1.2	-0.9	-2.3	-0.0	-2.4	0.6	-2.1	-1.3	-0.6	-0.5	-1.0	-1.1	-1.1	-0.8	-0.7	-1.0	-1.1	-1.5	-1.0
Gout (self-reported)	0.4	0.6	2.0	-0.6	-0.7	-0.9	-0.8	-0.9	-0.6	-0.2	0.1	-0.5	-0.5	-1.4	-1.2	0.4	-0.8	-1.1	-0.8	-0.9	-0.6	-1.0	-0.8	-0.6	-0.8
Eye problems/disorders: None of the above	0.4	0.5	3.3	0.4	0.4	0.3	0.8	0.4	1.0	-0.1	0.8	-0.5	1.2	0.9	1.8	-0.9	0.4	0.6	0.5	0.1	0.5	0.4	0.4	0.7	0.4
Had major operations	0.4	0.5	5.1	-0.5	-0.3	-0.2	-0.6	-0.4	-0.4	0.6	-1.4	0.6	-2.3	-0.4	-1.1	-0.1	-0.3	-0.4	-0.3	0.0	-0.2	-0.1	-0.2	-0.8	-0.3
Smoking status: Previous	0.4	0.7	6.3	-1.1	-0.3	0.0	-0.5	-0.2	1.7	0.0	-0.5	-0.5	-2.5	0.4	-0.4	-0.5	-0.4	-0.1	-0.4	-0.3	-1.4	-0.2	-0.2	-0.7	-0.3
Ever had bowel cancer screening	0.4	0.4	5.1	-0.2	-0.3	-0.3	-0.5	-0.2	-1.1	-0.2	0.0	-0.7	2.2	-0.4	0.8	-0.7	-0.3	-0.3	-0.5	-0.7	-0.2	-0.5	-0.2	-0.6	-0.3
Osteoporosis (self-reported)	0.4	0.5	1.9	0.6	0.6	0.5	0.8	0.7	1.0	-0.1	0.4	0.4	0.8	1.3	0.9	1.4	0.6	0.7	0.5	0.6	0.6	0.5	0.4	0.6	0.5
Medication: Aspirin	0.4	0.6	2.4	0.7	0.8	0.7	0.5	0.8	1.0	0.1	1.6	0.8	0.4	0.7	1.0	-0.5	0.8	0.7	0.6	0.4	0.8	0.6	1.0	0.3	0.8
Smoking status: Current	0.4	0.6	2.8	0.5	0.7	1.0	0.6	0.8	1.7	0.3	0.4	-0.1	-0.7	1.2	-0.3	-0.0	0.7	0.9	0.9	0.8	0.3	0.8	0.7	1.0	0.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.5	0.8	0.7	0.8	0.1	0.9	0.8	-0.2	0.5	0.7	1.2	0.8	0.9	0.6	0.7	0.8	0.6	0.4	0.4	0.7	1.0	0.4	0.9
Medication: Bendroflumethiazide	0.4	0.5	3.3	0.5	0.6	0.6	0.4	0.5	1.2	0.2	1.7	-0.3	1.8	0.5	0.9	0.2	0.6	0.6	0.6	0.3	0.2	0.4	0.8	0.3	0.6
Ever smoked	0.4	0.7	5.8	-0.9	-0.2	0.1	-0.6	-0.1	1.0	-0.1	-0.9	-1.0	-2.4	0.5	-1.3	-1.3	-0.3	0.1	-0.2	-0.4	-1.4	-0.2	-0.1	-0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	4.0	0.7	0.6	0.4	0.7	0.4	1.1	0.1	-0.2	2.0	-0.5	0.7	0.2	1.3	0.6	0.6	0.7	1.0	0.6	0.8	0.5	0.6	0.6
Heart disease (siblings)	0.4	0.5	2.0	0.8	0.7	0.9	0.7	0.6	0.5	0.3	1.0	-0.2	1.4	0.7	0.6	0.4	0.7	0.7	0.9	0.6	0.4	0.6	0.7	1.1	0.7
Schizophrenia (2018)	0.3	0.6	3.5	-0.5	-0.4	-0.4	-0.5	-0.4	-0.7	-1.9	-1.3	0.3	-1.5	-0.8	-1.4	0.2	-0.4	-0.5	-0.4	-0.4	-0.3	-0.4	-0.4	-0.4	-0.3
Alzheimer’s Disease (in mother)	0.3	0.3	4.3	-0.6	-0.2	-0.2	-0.3	-0.1	0.3	0.0	-0.3	0.5	-2.1	-0.2	-0.7	-0.6	-0.2	-0.3	-0.3	-0.1	-0.0	-0.0	-0.2	-0.5	-0.2
LDL Cholesterol	0.3	0.4	1.1	-0.4	-0.7	-0.7	-0.5	-0.9	0.2	-0.1	-0.1	-1.0	0.2	-0.6	0.1	-0.9	-0.8	-0.6	-0.9	-0.8	-0.7	-0.9	-1.0	-0.7	-0.8
Schizophrenia (2014)	0.3	0.7	6.6	-0.6	-0.3	-0.4	-0.5	-0.4	-0.8	-1.3	-1.5	0.2	-2.6	-0.9	-1.6	-0.3	-0.4	-0.6	-0.4	-0.4	-0.1	-0.4	-0.5	-0.2	-0.4
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	-0.3	-0.6	-0.3	-1.0	-0.8	-0.3	0.0	-0.3	-0.0	0.2	-1.0	0.7	-0.4	-0.8	-0.7	-0.4	-0.2	-0.4	-0.5	-0.5	-1.0	-0.5
Average weekly fortified wine intake	0.3	0.3	2.1	-0.5	-0.3	-0.3	-0.8	-0.2	0.0	0.2	0.3	-1.5	0.1	0.2	0.1	-1.3	-0.4	-0.1	-0.7	-1.1	-0.2	-0.7	-0.2	-0.8	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	5.2	-0.4	-0.1	-0.2	-0.3	-0.1	1.1	-0.2	0.0	-0.2	-2.3	-0.1	-1.4	0.3	-0.2	-0.2	-0.2	-0.2	-0.4	-0.2	-0.1	-0.3	-0.1
Waist circumference	0.3	1.2	11.3	0.9	0.9	0.7	0.3	0.9	3.4	0.3	1.9	0.4	-1.3	0.3	-1.4	-0.4	0.9	0.5	0.7	0.4	0.9	0.9	1.2	0.5	0.9
Hearing difficulty/problems with background noise	0.3	0.6	2.0	0.7	0.7	0.6	1.0	0.6	1.4	0.4	0.7	0.9	0.2	0.7	0.4	0.6	0.6	0.6	0.9	0.9	0.2	0.8	0.6	1.3	0.7
Fluid intelligence score	0.3	0.7	3.8	0.5	0.1	0.1	1.1	-0.1	-1.5	0.0	-0.6	1.7	1.1	0.5	1.2	2.0	0.2	0.4	0.3	0.8	0.8	0.2	-0.1	0.3	0.0
Hair/balding pattern: Pattern 3	0.3	0.5	4.9	-0.2	-0.2	-0.3	0.0	-0.3	-0.8	0.4	-0.3	-0.2	2.2	0.2	2.2	0.5	-0.2	-0.1	-0.1	-0.1	0.1	-0.2	-0.3	-0.1	-0.2
Noisy workplace	0.3	0.4	3.2	0.4	0.6	0.6	0.2	0.6	1.0	-0.1	0.1	0.1	-1.0	-0.0	-1.8	0.5	0.6	0.6	0.7	0.6	0.2	0.4	0.8	0.3	0.7
Mouth/teeth dental problems: Dentures	0.3	0.6	4.9	0.2	0.4	0.4	-0.2	0.4	2.2	0.5	1.1	-0.9	-0.8	0.8	-0.4	-1.5	0.4	0.6	0.1	-0.3	0.1	0.4	0.6	-0.3	0.4
Lung cancer (father)	0.3	0.4	1.5	0.2	0.2	0.3	0.5	0.1	0.9	0.2	-0.3	0.6	-1.2	-0.6	-0.8	1.2	0.2	0.1	0.7	0.7	-0.4	0.5	0.2	1.1	0.4
Exposure to tobacco smoke at home	0.3	0.4	3.3	0.1	0.4	0.3	0.2	0.4	1.8	0.2	0.1	0.1	-1.5	0.3	-0.8	-0.8	0.4	0.4	0.4	0.3	0.1	0.4	0.4	0.3	0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	3.4	-0.5	-0.5	-0.4	-0.3	-0.5	-1.8	-0.6	-1.4	0.1	-0.9	-0.3	-0.8	-0.1	-0.5	-0.2	-0.2	0.1	-0.9	-0.2	-0.5	-0.0	-0.4
Arm fat-free mass (right)	0.3	1.3	15.3	0.6	0.5	0.2	-0.5	0.5	3.9	0.6	1.7	-0.3	-2.4	-0.3	-1.0	-1.0	0.4	-0.0	-0.2	-0.5	0.9	0.3	0.8	-0.6	0.4
Worry too long after embarrassment	0.3	0.6	3.9	0.6	0.4	0.2	0.8	0.2	-1.0	-0.1	-0.2	2.0	-0.9	-0.4	-1.2	0.6	0.5	0.2	0.7	1.0	0.7	0.5	0.3	0.8	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	2.6	0.6	0.3	0.3	0.1	0.4	-0.7	-0.6	0.3	0.1	0.7	-0.1	-0.8	-1.6	0.4	0.1	0.2	0.1	0.9	0.4	0.4	-0.0	0.4
Pulse wave peak to peak time	0.3	0.3	2.7	0.3	0.3	0.3	0.8	0.3	-0.3	-0.5	0.3	0.5	1.7	0.7	0.7	0.5	0.3	0.5	0.4	0.6	0.6	0.4	0.1	0.5	0.2
Emphysema/chronic bronchitis	0.3	0.4	1.0	0.5	0.7	0.5	0.4	0.9	0.9	0.2	1.0	0.8	-0.3	0.6	0.1	-0.1	0.7	0.7	0.6	0.5	0.6	0.4	0.9	-0.3	0.8
Long-standing illness, disability or infirmity	0.3	0.4	3.3	0.1	0.3	0.2	-0.0	0.4	1.2	-0.1	0.5	0.7	-1.8	0.1	-1.5	0.9	0.3	0.4	0.2	0.1	0.4	0.3	0.5	-0.1	0.3
Breast cancer (self-reported)	0.3	0.4	4.0	-0.1	0.3	0.4	0.4	0.2	2.0	0.2	0.6	-0.0	-1.1	0.8	0.7	-0.1	0.2	0.5	0.5	0.5	-0.7	0.4	0.2	0.8	0.4
Guilty feelings	0.3	0.5	3.3	-0.3	-0.4	-0.4	-0.6	-0.4	-0.2	-0.2	-0.6	-0.5	-1.8	-0.5	-1.5	-1.0	-0.3	-0.3	-0.4	-0.6	-0.1	-0.6	-0.2	-0.9	-0.2
Wears glasses or contact lenses	0.3	0.4	1.3	-0.7	-0.7	-0.7	-0.6	-0.7	-0.2	0.2	-0.8	-0.3	-1.1	-0.5	-0.8	-0.3	-0.7	-0.6	-0.5	-0.5	-0.9	-0.6	-0.5	-0.5	-0.6
Medication: Blood pressure	0.3	0.5	5.0	-0.7	-0.3	-0.2	-0.9	-0.2	-0.2	-0.1	0.3	-0.7	-0.7	-0.3	-0.4	-2.2	-0.3	-0.3	-0.6	-0.8	-0.4	-0.5	0.1	-1.3	-0.2
Leg fat percentage (left)	0.3	0.9	9.1	0.7	0.6	0.6	-0.0	0.6	3.0	0.0	2.0	-0.6	0.5	-0.2	-1.9	-0.2	0.6	0.1	0.4	0.0	0.7	0.4	0.9	0.1	0.6
Leg fat mass (left)	0.3	1.2	14.4	0.8	0.7	0.5	-0.1	0.6	3.8	0.1	2.1	-0.4	-0.5	-0.3	-1.7	-0.6	0.7	0.1	0.3	-0.1	1.1	0.5	1.0	-0.1	0.7
Arm predicted mass (left)	0.3	1.3	15.2	0.6	0.6	0.2	-0.5	0.5	3.9	0.6	1.6	-0.1	-2.3	-0.3	-1.2	-0.8	0.4	-0.0	-0.1	-0.5	1.0	0.4	0.9	-0.6	0.5
Crohns Disease (2017)	0.2	0.4	2.0	0.3	0.1	0.1	1.1	0.1	0.3	-0.5	1.4	0.9	-1.4	0.4	0.0	0.9	0.1	0.2	0.2	0.3	0.9	0.3	-0.2	1.0	-0.1
Primary Biliary Cirrhosis	0.2	0.2	1.4	-0.0	-0.0	-0.3	0.5	-0.2	-1.0	-0.2	-1.0	0.7	0.5	0.1	1.2	0.9	-0.0	-0.1	0.1	0.3	0.0	0.1	-0.3	0.2	-0.2
Cardiovascular Disease	0.2	0.5	2.5	-0.5	-0.5	-0.5	-0.7	-0.6	-0.3	0.2	0.3	-1.1	0.1	-1.6	-0.4	-1.4	-0.4	-1.0	-0.6	-0.7	-0.4	-0.9	-0.5	-1.0	-0.5
Systolic blood pressure, automated reading	0.2	0.5	2.0	-0.6	-0.4	-0.3	-0.9	-0.4	0.8	0.2	0.4	-1.4	-0.9	-0.6	-0.0	-0.9	-0.4	-0.5	-0.7	-0.9	-0.6	-0.8	-0.3	-1.1	-0.4
Townsend deprivation index at recruitment	0.2	0.3	2.7	0.3	0.2	0.3	0.2	0.2	1.1	-0.0	0.8	-0.8	0.5	0.6	0.3	1.7	0.2	0.4	0.4	-0.0	-0.6	-0.1	0.3	0.5	0.3
Diabetes (self-reported)	0.2	0.3	1.1	-0.4	-0.4	-0.5	-0.4	-0.5	0.9	0.2	0.3	0.8	-0.9	-0.4	-1.0	0.6	-0.3	-0.6	-0.5	-0.3	0.3	-0.4	-0.4	-0.5	-0.5
Weight	0.2	1.2	14.4	0.4	0.3	-0.0	-0.6	0.2	3.8	0.1	1.6	-0.4	-1.7	-0.4	-1.7	-1.1	0.2	-0.3	-0.2	-0.5	0.7	0.2	0.6	-0.8	0.2
Trunk fat-free mass	0.2	1.3	10.1	-0.1	-0.1	-0.5	-1.1	-0.2	2.8	0.6	0.6	-0.4	-3.2	-0.6	-1.2	-1.7	-0.3	-0.6	-0.9	-1.1	0.4	-0.2	0.1	-1.2	-0.3
Medication: Lansoprazole	0.2	0.2	1.6	0.0	0.1	-0.2	-0.2	0.0	-0.2	0.2	0.1	-0.6	0.3	-0.8	-0.4	-1.3	0.1	-0.5	0.0	-0.4	0.6	-0.3	0.1	-0.1	0.1
Prospective memory result	0.2	0.2	1.5	0.2	0.0	-0.2	-0.5	0.1	0.6	0.3	0.6	-0.8	0.6	-0.1	-0.8	-1.2	0.1	-0.1	-0.1	-0.2	0.0	-0.1	0.2	-0.5	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	4.5	-0.7	-0.7	-0.8	-0.8	-0.6	-1.5	0.2	-1.8	0.8	-2.1	-0.6	-0.0	-0.4	-0.7	-0.6	-0.8	-0.4	-0.4	-0.6	-0.7	-1.1	-0.7
Trunk predicted mass	0.2	1.2	9.2	-0.0	-0.1	-0.4	-1.0	-0.3	2.8	0.6	0.7	-0.4	-3.0	-0.5	-1.1	-1.6	-0.3	-0.6	-0.9	-1.1	0.5	-0.2	0.1	-1.2	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	3.8	-0.0	-0.3	-0.3	-0.0	-0.4	-2.0	-0.8	-1.3	0.6	0.3	-0.2	-0.7	0.7	-0.3	-0.4	-0.2	0.0	0.2	-0.2	-0.3	-0.1	-0.3
Blood clot in the leg (DVT)	0.2	0.3	2.8	0.4	0.2	0.0	0.4	0.0	0.7	0.2	-0.7	1.7	-0.9	0.2	0.0	0.9	0.2	0.2	0.3	0.6	0.3	0.4	0.1	0.3	0.2
Body fat percentage	0.2	0.9	6.8	-0.4	-0.6	-0.6	-1.0	-0.6	1.5	-0.3	0.7	-1.5	0.5	-1.1	-2.6	-0.8	-0.6	-1.0	-0.7	-1.0	-0.3	-0.7	-0.4	-0.9	-0.6
Leg fat percentage (right)	0.2	0.8	6.7	-0.1	-0.1	-0.2	-0.7	-0.2	2.2	0.0	1.2	-1.2	-0.1	-0.8	-2.6	-0.8	-0.1	-0.7	-0.3	-0.7	0.0	-0.4	0.1	-0.5	-0.2
Medication: Ibuprofen	0.2	0.3	1.8	-0.3	-0.2	-0.3	-0.5	-0.2	0.2	-0.1	-0.0	-1.3	-0.8	-0.4	-0.6	-0.7	-0.3	-0.4	-0.5	-0.7	-0.1	-0.6	-0.2	-0.7	-0.3
Medication: Allopurinol	0.2	0.2	1.2	0.5	0.4	0.2	0.0	0.4	-0.0	-0.4	1.1	0.4	-0.4	-0.5	-0.9	0.8	0.4	0.0	0.3	0.2	0.5	0.2	0.5	0.2	0.4
Medication: Omeprazole	0.2	0.2	1.6	-0.1	0.0	0.1	-0.5	0.2	0.5	0.2	-0.4	-0.6	-1.3	-0.4	-1.2	-0.3	0.0	0.0	0.0	-0.2	-0.1	0.0	0.3	-0.2	0.2
Medication: Seretide 50 evohaler	0.2	0.2	1.6	-0.4	0.0	0.2	-0.6	0.1	0.6	0.3	0.5	-0.4	-0.8	0.7	-1.3	-0.5	-0.0	0.1	-0.2	-0.1	-0.3	0.1	0.1	-0.6	-0.0
Whole body fat mass	0.2	0.9	6.8	-0.0	-0.2	-0.4	-0.9	-0.3	2.6	-0.1	1.0	-1.2	-0.4	-0.9	-2.3	-1.1	-0.2	-0.7	-0.5	-0.9	0.2	-0.4	0.1	-0.9	-0.3
Leg fat mass (right)	0.2	1.0	11.1	0.4	0.3	0.2	-0.5	0.2	3.3	0.1	1.7	-0.8	-0.7	-0.5	-2.0	-1.0	0.3	-0.3	-0.1	-0.5	0.7	0.1	0.6	-0.4	0.2
Arm predicted mass (right)	0.2	1.2	13.2	0.6	0.5	0.1	-0.6	0.4	3.6	0.6	1.5	-0.2	-2.4	-0.5	-1.2	-1.2	0.4	-0.2	-0.2	-0.5	1.0	0.3	0.7	-0.7	0.4
Whole body fat-free mass	0.2	1.2	13.5	0.7	0.5	0.2	-0.4	0.4	3.7	0.4	1.5	-0.0	-2.4	-0.0	-0.8	-1.2	0.4	0.0	-0.2	-0.5	1.1	0.4	0.8	-0.6	0.4
Diabetes diagnosed by doctor	0.2	0.4	1.4	-0.5	-0.5	-0.7	-0.5	-0.6	0.8	-0.1	0.3	0.6	-1.0	-0.5	-1.2	0.7	-0.5	-0.7	-0.6	-0.4	0.2	-0.5	-0.5	-0.7	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.3	0.2	0.1	0.2	0.3	-0.0	0.8	-0.2	1.1	0.8	-0.6	-0.4	-0.7	1.2	0.1	-0.0	0.2	0.4	0.1	0.2	-0.1	0.5	0.0
Whole body water mass	0.2	1.4	15.1	0.8	0.7	0.4	-0.2	0.6	3.9	0.4	1.7	0.1	-2.4	0.2	-0.8	-1.1	0.6	0.3	-0.0	-0.3	1.3	0.6	1.0	-0.4	0.6
Average weekly champagne plus white wine intake	0.2	0.2	0.4	0.1	0.4	0.5	0.3	0.6	-0.5	-0.4	0.3	-0.5	0.5	0.6	-0.5	-0.0	0.4	0.6	0.6	0.4	-0.3	0.4	0.4	0.7	0.5
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	-0.0	-0.3	-0.3	-0.4	-0.4	-0.7	0.2	0.6	-0.9	0.5	-0.6	-0.9	-0.5	-0.3	-0.3	-0.3	-0.7	0.2	-0.4	-0.2	-0.0	-0.3
Medication: Lisinopril	0.2	0.3	1.5	-0.5	-0.4	-0.3	-0.9	-0.3	-0.3	0.8	-0.3	-0.6	-0.2	-0.2	0.8	-0.4	-0.4	-0.4	-0.6	-0.6	-0.6	-0.6	-0.2	-1.2	-0.3
Alcohol drinker status: Never	0.2	0.2	1.0	0.7	0.4	0.5	0.3	0.3	-0.0	-0.1	0.3	1.0	0.1	0.2	0.3	-0.3	0.4	0.2	0.5	0.7	0.7	0.4	0.5	0.0	0.5
Basal metabolic rate	0.2	1.2	13.0	0.5	0.4	0.0	-0.5	0.3	3.6	0.3	1.4	-0.2	-2.3	-0.3	-1.2	-1.2	0.3	-0.1	-0.3	-0.6	1.0	0.3	0.7	-0.8	0.3
Arm fat-free mass (left)	0.2	1.2	14.4	0.7	0.5	0.2	-0.6	0.4	3.8	0.5	1.6	-0.1	-2.2	-0.3	-1.2	-0.9	0.4	-0.1	-0.2	-0.6	1.0	0.3	0.8	-0.7	0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.0	0.5	0.5	0.5	0.1	0.5	0.7	0.1	0.2	-0.0	-0.5	-0.0	-1.0	0.2	0.5	0.4	0.5	0.2	0.4	0.4	0.6	0.5	0.6
Supplements: Calcium	0.2	0.2	1.4	0.1	-0.3	-0.4	-0.6	-0.2	-0.6	0.4	-0.4	-1.2	0.7	-0.0	0.6	-0.6	-0.3	-0.2	-0.3	-0.6	-0.5	-0.5	-0.2	-0.4	-0.2
Alzheimer’s Disease (in father)	0.1	0.2	0.8	-0.3	-0.4	-0.4	0.1	-0.4	0.1	0.1	-0.3	0.9	-0.4	-0.7	-0.1	0.3	-0.3	-0.5	-0.3	0.3	0.2	-0.1	-0.5	-0.5	-0.5
Hypothyroidism (self reported)	0.1	0.2	0.7	0.7	0.6	0.4	0.0	0.8	-0.1	-0.2	0.5	-0.8	0.3	-0.1	-0.3	-0.3	0.7	0.4	0.5	-0.2	0.6	0.1	0.8	0.4	0.7
Medication: Metformin	0.1	0.2	0.9	-0.3	-0.2	-0.4	-0.3	-0.3	0.8	0.2	0.6	0.7	-0.9	-0.7	-0.5	0.5	-0.2	-0.6	-0.3	-0.0	-0.0	-0.1	-0.2	-0.5	-0.3
High blood pressure	0.1	0.3	1.9	-0.4	0.1	0.1	-0.8	0.1	0.5	0.3	0.7	-0.7	-0.4	-0.4	0.3	-1.4	0.1	-0.2	-0.4	-0.6	-0.1	-0.2	0.4	-1.0	0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.3	0.2	0.0	-0.1	0.0	-0.1	-0.6	0.5	-0.6	0.1	1.1	-0.4	0.4	0.6	-0.0	-0.1	0.2	0.2	-0.4	0.1	-0.1	0.5	0.0
Medication: Levothyroxine sodium	0.1	0.2	0.8	0.5	0.6	0.6	0.3	0.6	0.2	-0.2	-0.5	0.6	-0.3	0.2	0.0	-0.2	0.6	0.4	0.5	0.3	0.9	0.5	0.7	0.5	0.6
High blood pressure (mother)	0.1	0.1	0.6	-0.0	0.2	0.2	-0.2	0.2	-0.3	0.2	0.8	-0.7	0.0	0.2	0.0	-0.4	0.2	0.3	-0.1	-0.6	0.4	-0.3	0.3	-0.5	0.2
Forced vital capacity (FVC)	0.1	0.5	2.1	-0.3	-0.5	-0.9	-0.8	-0.4	-1.5	0.2	-1.3	0.6	-0.8	-0.5	0.3	-0.1	-0.5	-0.6	-0.8	-0.6	-0.1	-0.6	-0.5	-1.2	-0.5
Father’s age at death	0.1	0.2	1.0	0.1	0.2	0.2	0.8	0.2	0.0	-0.3	-0.1	1.0	-0.5	0.7	0.5	0.8	0.2	0.4	0.3	0.5	0.1	0.3	0.0	0.5	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	1.2	-0.0	0.1	0.1	-0.4	0.1	0.3	-0.0	0.1	-1.1	-0.7	-0.2	-0.2	-0.7	0.0	-0.2	-0.2	-0.4	0.1	-0.2	0.2	-0.6	0.1
Depression (self-reported)	0.1	0.2	1.5	0.0	0.1	0.1	-0.3	0.1	-0.4	-0.5	-0.6	-0.5	-0.2	0.2	-1.2	-0.2	0.1	0.2	-0.2	-0.3	0.7	-0.1	0.2	-0.4	0.1
Hair/balding pattern: Pattern 4	0.1	0.2	0.7	-0.2	-0.3	-0.4	-0.4	-0.2	0.6	-0.4	0.7	-0.8	0.7	-0.8	0.6	-0.4	-0.3	-0.3	-0.3	-0.4	-0.4	-0.5	-0.2	-0.8	-0.2
Peak expiratory flow (PEF)	0.1	0.1	1.4	-0.2	-0.1	-0.1	-0.1	0.1	0.0	-0.2	-0.3	0.5	-1.2	-0.2	0.6	0.3	-0.1	0.0	0.1	0.3	-0.6	-0.1	0.0	-0.4	0.1
Loud music exposure frequency	0.1	0.2	1.0	0.2	0.3	0.1	0.2	0.1	-0.6	0.4	-0.2	1.0	-0.3	-0.1	-0.6	0.8	0.3	0.2	0.4	0.4	0.0	0.1	0.3	0.2	0.3
Glaucoma (self-reported)	0.1	0.2	0.5	-0.1	-0.4	-0.5	-0.2	-0.5	-0.5	0.1	0.5	-0.6	0.7	-0.6	-0.4	0.4	-0.4	-0.3	-0.3	-0.5	-0.3	-0.5	-0.3	0.1	-0.4
Forced vital capacity (FVC), Best measure	0.1	0.5	1.7	-0.5	-0.6	-0.8	-0.7	-0.6	-1.3	0.4	-1.3	0.6	-1.0	-0.1	0.5	-0.3	-0.7	-0.5	-0.9	-0.6	-0.2	-0.5	-0.6	-1.3	-0.7
Medication: Blood pressure	0.1	0.3	1.6	0.3	0.4	0.2	-0.0	0.5	1.3	0.6	0.8	-0.1	0.5	0.2	0.7	-0.4	0.5	0.1	0.0	-0.3	0.9	0.1	0.5	-0.5	0.4
Heart disease (mother)	0.1	0.1	0.4	0.1	0.1	0.2	0.1	0.1	0.2	-0.1	0.6	-0.2	0.4	0.6	0.4	0.6	0.1	0.5	0.1	-0.1	0.4	-0.0	0.3	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	1.1	-0.5	-0.1	0.1	-0.0	0.0	-0.0	-0.1	0.2	-0.2	-1.1	0.1	-0.2	-0.4	-0.1	0.1	0.0	0.0	-0.7	-0.2	-0.1	-0.1	-0.0
Hypertension (Self-reported)	0.1	0.3	1.3	0.2	0.7	0.7	-0.2	0.7	0.8	0.3	1.1	-0.1	-0.0	0.2	0.4	-0.8	0.7	0.4	0.2	0.0	0.5	0.4	1.0	-0.6	0.7
Illnesses of father: Heart disease	0.1	0.1	0.3	-0.2	0.0	0.1	-0.3	0.0	0.3	0.0	0.5	-0.4	-0.2	-0.0	0.6	-0.5	0.0	-0.2	-0.3	-0.4	0.4	-0.2	-0.1	-0.3	-0.1
Osteoarthritis (self-reported)	0.1	0.2	0.6	0.5	0.5	0.3	-0.2	0.5	0.5	0.3	0.1	-0.2	-0.5	-0.8	-0.2	-0.6	0.5	0.2	0.2	-0.1	0.8	0.2	0.7	-0.2	0.4
Hearing aid user	0.1	0.1	0.4	-0.1	0.0	-0.0	-0.1	-0.1	0.2	0.3	0.0	-0.1	-0.6	0.1	-0.5	-0.6	-0.0	0.0	-0.1	-0.4	0.0	-0.1	-0.0	0.2	-0.0
Mother’s age at death	0.1	0.2	1.3	0.1	0.2	0.3	0.1	0.1	-1.0	-0.1	-0.4	1.1	0.4	0.3	-0.1	-0.7	0.2	0.2	0.1	0.5	0.2	0.3	0.3	-0.5	0.2
Irritability	0.1	0.2	2.5	-0.1	-0.1	-0.1	-0.0	-0.2	-0.1	0.5	-0.2	0.2	-0.9	-0.3	-1.6	1.1	-0.1	-0.0	-0.0	-0.2	-0.3	-0.3	-0.1	0.1	-0.1
Myopia	0.1	0.2	1.4	-0.2	-0.0	-0.2	0.0	0.1	-0.4	-0.6	-0.8	-0.0	-0.9	-0.0	-0.6	-1.2	0.0	-0.0	-0.1	-0.2	0.1	0.0	-0.1	0.1	-0.0
Vascular/heart problems diagnosed by doctor	0.1	0.2	1.0	-0.1	-0.4	-0.4	0.4	-0.4	-0.8	-0.3	-1.0	0.2	0.1	0.4	-0.5	0.9	-0.5	0.1	0.0	0.3	-0.4	-0.0	-0.6	0.7	-0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.8	0.2	0.2	0.3	0.2	0.2	0.1	0.1	0.4	0.4	0.6	0.1	0.9	0.6	0.2	0.2	0.2	0.3	-0.1	0.3	0.3	0.0	0.2
Bipolar Disorder (2011)	0.0	0.0	0.3	-0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.5	0.0	0.0	0.0	0.0	0.0	0.0	0.2
Hair Pigment	0.0	0.2	1.8	0.1	0.1	0.4	-0.3	0.3	0.9	-0.2	0.1	-0.2	-1.3	0.3	-0.1	0.2	0.1	0.1	-0.3	-0.2	1.4	0.3	0.2	-0.3	0.0
Tanning	0.0	0.4	2.4	-0.3	-0.6	-0.3	-0.5	-0.6	0.8	-0.5	-0.1	-1.5	1.0	-0.1	-0.1	-1.1	-0.6	-0.4	-0.5	-0.6	-0.8	-0.8	-0.5	-0.6	-0.6
Headache pain in last month	0.0	0.1	0.3	-0.1	-0.2	-0.1	-0.2	-0.2	-0.5	-0.0	-0.3	-0.3	-0.6	-0.3	-0.3	-0.1	-0.1	-0.4	-0.1	-0.2	0.4	-0.2	-0.1	-0.1	-0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.3	-0.1	-0.1	0.0	0.1	-0.0	0.1	-0.2	-0.3	0.5	-0.2	0.5	-0.4	-0.2	-0.1	0.1	0.1	0.3	-0.1	0.0	-0.0	-0.0	-0.0

Hub : Genes

HEMK1

Models

Trait associations